STEM CELL EXHAUSTION

/ DISEASE & DISORDERS, HALLMARKS OF AGING, SCIENCE / By
  1. Hematopoietic Stem cell exhaustion impacted by p18INK4C and p21Cip1/Waf1 in opposite manners
  2. mTOR mediates Wnt-induced epidermal Stem cell exhaustion and aging
  3. Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
  4. The Polycomb group gene Ezh2 prevents hematopoietic Stem cell exhaustion
  5. Relationships between Stem cell exhaustion , tumour suppression and ageing
  6. Stem cell exhaustion and leukemogenesis
  7. Progeria of Stem cells: Stem cell exhaustion in Hutchinson-Gilford progeria syndrome
  8. Short telomeres and Stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice
  9. Genetic regulation of hematopoietic Stem cell exhaustion during development and growth
  10. Could metabolic syndrome, lipodystrophy, and aging be mesenchymal Stem cell exhaustion syndromes?
  11. … ‐up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic Stem cell exhaustion
  12. Pre-CFU-S quiescence and Stem cell exhaustion after cytostatic drug treatment: protective effects of the inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK)
  13. … be the intracellular determinants of longevity implicated in the progeric influence of obesity: Insulin, IGF-1, and leptin may all conspire to promote Stem cell exhaustion
  14. Stem cell exhaustion and atherosclerosis
  15. Hematopoietic Stem cell Quiescence Maintained by p21cip1/waf1
  16. Stem cell aging: what bleach can teach
  17. Growth signaling at the nexus of Stem cell life and death
  18. p21 loss compromises the relative quiescence of forebrain Stem cell proliferation leading to exhaustion of their proliferation capacity
  19. Stem cells and the rate of living
  20. DNA repair is limiting for haematopoietic Stem cells during ageing
  21. A Limited Role for p21Cip1/Waf1 in Maintaining Normal Hematopoietic Stem cell Functioning
  22. Deconstructing Stem cell self-renewal: genetic insights into cell -cycle regulation
  23. Does Stem cell exhaustion result from combining hematopoietic
  24. Signaling circuitries controlling Stem cell fate: to be or not to be
  25. Epigenetic control of hematopoietic Stem cell aging the case of Ezh2
  26. Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
  27. The p53 tumor suppressor protein is a critical regulator of hematopoietic Stem cell behavior
  28. Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem cell exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.
  29. Understanding the Impact of Inflammation on Hematopoietic Stem Cells.
  30. Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and Stem cell loss
  31. Accumulation of DNA damage in hematopoietic Stem and progenitor cells during human aging
  32. Cellular aging leads to functional heterogeneity of hematopoietic Stem cells: a modeling perspective
  33. Balancing dormant and self-renewing hematopoietic Stem cells
  34. Telomere length dynamics in normal hematopoiesis and in disease states characterized by increased Stem cell turnover
  35. Controlling Stem cell proliferation: CKIs at work
  36. Cellular memory and hematopoietic Stem cell aging
  37. Enrichment of hematopoietic Stem cells with SLAM and LSK markers for the detection of hematopoietic Stem cell function in normal and Trp53 null mice
  38. Impaired hematopoietic Stem cell functioning after serial transplantation and during normal aging
  39. A dual role of p21 in Stem cell aging
  40. Mechanisms of Stem cell ageing
  41. Intrinsic and extrinsic control of haematopoietic Stem–cell self-renewal
  42. Runx family genes, niche, and Stem cell quiescence
  43. The haematopoietic Stem cell niche: new insights into the mechanisms regulating haematopoietic Stem cell behaviour
  44. Advances in hematopoietic Stem cell research through mouse genetics
  45. DNA repair is crucial for maintaining hematopoietic Stem cell function
  46. Regulation of hematopoietic Stem cell aging in vivo by a distinct genetic element
  47. Impaired Stem cell collection by consecutive courses of high-dose mobilizing chemotherapy using cyclophosphamide, etoposide, and G-CSF
  48. Peripheral Stem cell mobilization and engraftment in patients over age 60
  49. The chiaroscuro Stem cell : a unified Stem cell theory
  50. Quiescence regulators for hematopoietic Stem cell
  51. Hematopoietic Stem cell aging and self-renewal
  52. Etiology of limbal Stem cell transplantation failure
  53. DNA repair in Stem cell maintenance and conversion to cancer Stem cells
  54. Repopulating defect of mismatch repair–deficient hematopoietic Stem cells
  55. Genetic Uncoupling of the Regulation of Hematopoietic Stem cell Quiescence and Self-Renewal.
  56. MicroRNA miR-125a controls hematopoietic Stem cell number
  57. The nuclear receptor tailless induces long-term neural Stem cell expansion and brain tumor initiation
  58. Marrow aplasia developing 3 years after treatment with busulphan for chronic myeloid leukaemia
  59. Loss of proliferative capacity in immunohemopoietic Stem cells caused by serial transplantation rather than aging.
  60. Breaking the cell cycle of HSCs by p57 and friends
  61. G-CSF in the long-term treatment of cyclic neutropenia and chronic idiopathic neutropenia in adult patients.
  62. Mechanisms of hematopoietic Stem cell aging
  63. Failure of ocular surface reconstruction with amniotic membrane transplantation and living-related conjunctival limbal allograft
  64. Mechanisms that mediate Stem cell self‐renewal and differentiation
  65. Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells VI, University of Tübingen, Germany, September 14–16, 2006
  66. Live and let die: in vivo selection of gene-modified hematopoietic Stem cells via MGMT-mediated chemoprotection
  67. Clonal escape in Fanconi anemia: new hurdle for gene therapy?
  68. Aging of Hematopoietic Stem Cells LM Kamminga, R. van Os, A. Ausema, B. Dontje, G. DE HAAN
  69. Stem cell GENETICS AND GENOMICS: CONCISE REVIEW
  70. Identification of additional genetic alterations in RUNX1 related leukemias
  71. Simultaneous Maintenance of Human Cord Blood SCID‐Repopulating Cells and Expansion of Committed Progenitors at Low O2 Concentration (3%)
  72. How Stem cells age and why this makes us grow old
  73. Minimal residual disease and discontinuation of therapy in chronic myeloid leukemia: can we aim at a cure?
  74. Delayed mammary gland development in the p53+/m mouse, a model of accelerated aging
  75. Long-term interleukin-3 and intensive immunosuppression in the treatment of aplastic anemia.
  76. cell cycle entry of hematopoietic Stem and progenitor cells controlled by distinct cyclin-dependent kinase inhibitors
  77. The elements of Stem cell self-renewal: a genetic perspective
  78. Adult Stem cell maintenance and tissue regeneration in the ageing context: the role for A‐type lamins as intrinsic modulators of ageing in adult Stem cells and their …
  79. Iron overload and haematopoiesis in MDS: does blood transfusion promote progression to AML?
  80. Metabolic rate determines haematopoietic Stem cell self-renewal
  81. Vascular aging: insights from studies on cellular senescence, Stem cell aging, and progeroid syndromes
  82. Pivotal role for glycogen synthase kinase–3 in hematopoietic Stem cell homeostasis in mice
  83. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic Stem cells
  84. Hematopoietic Support by Endothelium
  85. Maintenance of quiescent hematopoietic Stem cells in the osteoblastic niche
  86. Germline Stem Cells: The First Guards of Heredity
  87. Cancer Stem cells and “Stemness” genes in neuro-oncology
  88. Granulocyte colony stimulating factor for bone marrow transplantation
  89. Deciphering the signaling pathways of cancer Stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways.
  90. Aplastic anaemia: considerations on the pathogenesis
  91. A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal Stem cell defects
  92. Age-Adjusted Telomere Length Is Not Associated with Variation in Hematological Parameters in Ageing Women
  93. Ewing sarcoma gene Ews regulates hematopoietic Stem cell senescence
  94. Notch signaling is required to maintain all neural Stem cell populations–irrespective of spatial or temporal niche
  95. A conundrum in mammalian hematopoietic Stem cell polarity
  96. CAMT: new findings and new questions
  97. cell cycle regulators in Stem cells
  98. Musashi1: a Stem cell marker no longer in search of a function
  99. The CDK inhibitors: potential targets for therapeutic Stem cell manipulations?
  100. Therapeutic targeting of a Stem cell niche
  101. Lessons learned from the study of JunB: new insights for normal and leukemia Stem cell biology
  102. The MicroRNA pathway plays a regulatory role in Stem cell division
  103. Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic Stem cell development
  104. HOXB4 overexpression mediates very rapid Stem cell regeneration and competitive hematopoietic repopulation
  105. p53 regulates hematopoietic Stem cell quiescence
  106. Regulation of hematopoietic Stem cells by the steel factor/KIT signaling pathway
  107. Hematopoietic Stem cells and the genetics of aging
  108. Stem cells and aging in the hematopoietic syStem
  109. Wnt signaling in the niche enforces hematopoietic Stem cell quiescence and is necessary to preserve self-renewal in vivo
  110. The role of the chromatin remodeler Mi-2β in hematopoietic Stem cell self-renewal and multilineage differentiation
  111. Adult Stem cell therapy beyond haemopoietic Stem cell transplantation? An update
  112. Calmodulin-dependent Protein Kinase IV Regulates Hematopoietic Stem cell Maintenance*♦
  113. mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to Stem cell renewal and …
  114. Cdc42: a signal coordinator in hematopoietic Stem cell maintenance
  115. Thioredoxin-interacting protein regulates hematopoietic Stem cell quiescence and mobilization under stress conditions
  116. Epigenetic regulation of Stem cells in cancer and aging
  117. IL‐3 and peripheral blood Stem cell harvesting
  118. Stem cell ageing: does it happen and can we intervene?
  119. Stem cell factor enhances dendritic cell development
  120. Effect of Stem cell factor (c-kit ligand), granulocyte-macrophage colony stimulating factor and interleukin 3 on hematopoietic progenitors in human long-term bone …
  121. Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic Stem cell property
  122. Stem–cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
  123. Stem cell injury and premature senescence
  124. Haemopoietic Stem cell inhibition: Potential for dose intensification
  125. JunB protects against myeloid malignancies by limiting hematopoietic Stem cell proliferation and differentiation without affecting self-renewal
  126. Genistein induces radioprotection by hematopoietic Stem cell quiescence
  127. Peripheral Stem cell mobilization and engraftment in patients over age 60
  128. PTEN negatively regulates neural Stem cell self-renewal by modulating G0-G1 cell cycle entry
  129. Ionizing radiation and aging: rejuvenating an old idea
  130. The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other Stem/progenitor cell populations
  131. Effects of prior therapy on the in vitro proliferative potential of Stem cell factor plus filgrastim-mobilized CD34-positive progenitor cells.
  132. DNA repair defects in Stem cell function and aging
  133. DNA damage response in adult Stem cells: pathways and consequences
  134. Telomere dysfunction induces environmental alterations limiting hematopoietic Stem cell function and engraftment
  135. Survival analysis of conjunctival limbal grafts and amniotic membrane transplantation in eyes with total limbal Stem cell deficiency
  136. Fanconi anemia Stem cells: going round and round
  137. Hematopoietic Stem cell self-renewal
  138. Polycomb group genes: keeping Stem cell activity in balance
  139. Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes Stem cell reserve for …
  140. Dedifferentiation rescues senescence of progeria cells but only while pluripotent
  141. Notch signaling in the regulation of Stem cell self-renewal and differentiation
  142. Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition
  143. Decline in self-renewal factors contributes to aging of the Stem cell niche in the Drosophila testis
  144. YY1 PcG function as a potential cancer therapeutic target
  145. Stem cell proliferation and quiescence—two sides of the same coin
  146. Awakening dormant haematopoietic Stem cells
  147. c-Myc controls the balance between hematopoietic Stem cell self-renewal and differentiation
  148. Multi-genetic events collaboratively contribute to Pten-null leukaemia Stem–cell formation
  149. Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenance
  150. Latent hematopoietic Stem cell toxicity associated with protracted drug administration
  151. Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic Stem cells
  152. Hematopoietic Stem cell development, aging and functional failure
  153. Bone marrow-derived cells: the influence of aging and cellular senescence
  154. Effects of dietary restriction on hematopoietic Stem–cell aging are genetically regulated
  155. p16INK4a and Stem cell Ageing: A Telomere-Independent Process?
  156. FILAMENTARY KERATITIS-A REVIEW OF ETIOP A REVIEW OF ETIOPATHOGENESIS AND MANAGEMENT THOGENESIS AND MANAGEMENT
  157. Limiting factors in murine hematopoietic Stem cell assays
  158. Pbx1 regulates self-renewal of long-term hematopoietic Stem cells by maintaining their quiescence
  159. Telomere dysfunction and Stem cell ageing
  160. The daunting task of modeling response to imatinib therapy in patients with chronic myelogenous leukemia
  161. Telomeres and telomerase in cancer Stem cells
  162. Pten deletion in adult neural Stem/progenitor cells enhances constitutive neurogenesis
  163. Endothelial progenitor cell mobilization after percutaneous coronary intervention
  164. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic Stem cells
  165. Tissue engineering of the cornea
  166. Intrinsic control of Stem cell fate
  167. Effects of Prior Therapy on the in Vitro Proliferative Potential of Stem cell Factor Plus Filgrastim-mobilized CD34-positive Progenitor Cells1
  168. Hematopoiesis: an evolving paradigm for Stem cell biology
  169. The pessimist’s and optimist’s views of adult neurogenesis
  170. Mechanisms controlling hematopoietic Stem cell functions during normal hematopoiesis and hematological malignancies
  171. Mouse Model: Telomeres and Telomerase in Stem cell and Cancer
  172. Stem cell model of hematopoiesis
  173. Goralatide (AcSDKP), a negative growth regulator, protects the Stem cell compartment during chemotherapy, enhancing the myelopoietic response to GM‐CSF
  174. A risk-benefit assessment of epoetin in the management of anaemia associated with cancer
  175. Compartmentalized organization: a common and required feature of Stem cell niches?
  176. Tuning mTORC1 activity for balanced self-renewal and differentiation
  177. Gene therapy approaches for Stem cell protection
  178. Loss of the Rho GTPase activating protein p190-B enhances hematopoietic Stem cell engraftment potential
  179. Hematopoietic Stem cells and aging
  180. HEMATOPOIETIC Stem cell TRANSFER: LBNT1 VIRUS VECTORS
  181. The stromal cells’ guide to the Stem cell universe
  182. Regulation of murine hematopoietic Stem cell quiescence by Dmtf1
  183. Signaling through BMPR-IA regulates quiescence and long-term activity of neural Stem cells in the adult hippocampus
  184. Tumor suppressor dosage regulates Stem cell dynamics during aging
  185. Mesenchymal Stem cell transplantation for tissue repair
  186. EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
  187. Telomeres in hematopoietic Stem cells
  188. Regulation of Stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with …
  189. The roles of EZH2 in cell lineage commitment
  190. Hematopoietic Stem cell aging: wrinkles in Stem cell potential
  191. Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition
  192. Genomic instability in induced Stem cells
  193. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
  194. Human skin Stem cells and the ageing process
  195. Polycomb repressive complex 2 is dispensable for maintenance of embryonic Stem cell pluripotency
  196. Ontogenic growth of the haemopoietic Stem cell pool in humans
  197. Inside Blood: a roadmap to the best and brightest
  198. A low level of reactive oxygen species selects for primitive hematopoietic Stem cells that may reside in the low-oxygenic niche
  199. Stem cells, DNA damage, ageing and cancer
  200. Hematopoietic Stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
  201. Polycomb repressive complex 2 (PRC2) restricts hematopoietic Stem cell activity
  202. Maintenance of adult Stem cells: Role of the Stem cell niche
  203. The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic Stem cells
  204. Metabolic regulation of hematopoietic Stem cells in the hypoxic niche
  205. Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell -cycle arrest
  206. Ci er chun he duan li yu qing jiang yu Oryzias melastigma shou ming de xiang guan xing yan jiu
  207. Clonal diversity of the Stem cell compartment
  208. Rac1 is required for epithelial Stem cell function during dermal and oral mucosal wound healing but not for tissue homeostasis in mice
  209. Manifestations and mechanisms of Stem cell aging
  210. 6 2 6 Editorials The Journal of Pediatrics November 1996
  211. Age-specific bone tumour incidence rates are governed
  212. Autologous limbal transplantation in unilateral chemical burns
  213. Tracking down the Stem cells of the intestine: strategies to identify adult Stem cells
  214. Gfi-1: another piece in the HSC puzzle
  215. Polycomb group proteins: multi-faceted regulators of somatic Stem cells and cancer
  216. Toward ‘SMART’Stem cells
  217. Expression of Stem cell markers on mononuclear cells derived from heparinized cadaveric organ donors before and after disconnection from the respirator
  218. Handbook on Immunosenescence: Basic Understanding and Clinical Applications
  219. Understanding cellular networks to improve hematopoietic Stem cell expansion cultures
  220. Regulation of Self-Renewing Divisions in Normal and Leukaemia Stem Cells
  221. Using naturally occurring tumours in dogs and cats to study telomerase and cancer Stem cell biology
  222. Impaired PBPC collection in patients with myeloma after high-dose melphalan
  223. Human Stem cell engraftment in sheep
  224. Transplantation of hematopoietic Stem cells from the peripheral blood
  225. The molecular specificity of action of the tetrapeptide acetyl‐n‐ser‐asp‐lys‐pro (AcSDKP) in the control of hematopoietic Stem cell proliferation
  226. Altered mammary gland development in the p53+/m mouse, a model of accelerated aging
  227. Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates
  228. Plzf regulates germline progenitor self-renewal by opposing mTORC1
  229. Telomere attrition occurs during ex vivo expansion of human dental pulp Stem cells
  230. Rapamycin and quasi-programmed aging: Four years later
  231. At the Stem of youth and health
  232. Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic Stem cell function
  233. Hematopoietic Stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
  234. cell cycle regulators in adult Stem cells
  235. Estimating dormant and active hematopoietic Stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics
  236. The p53–p66shc–manganese superoxide dismutase (MnSOD) network: a mitochondrial intrigue to generate reactive oxygen species
  237. Hemopoietic function after use of IL-1 with chemotherapy or irradiation
  238. A Stem cell fusion model of carcinogenesis.
  239. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
  240. Regulation of murine hematopoietic Stem cell quiescence by cyclin D binding myb-like transcription factor-1, Dmtf1
  241. Signaling pathways in self-renewing hematopoietic and leukemic Stem cells: do all Stem cells need a niche?
  242. Bone marrow Stem cell protection from chemotherapy by low–molecular-weight compounds
  243. Unraveling the complex regulation of Stem cells: implications for aging and cancer
  244. CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration
  245. 2010 International Forum on Stem Cells (November 11–13; Tianjin, China)
  246. The autophagy protein Atg7 is essential for hematopoietic Stem cell maintenance
  247. p53-mediated hematopoietic Stem and progenitor cell competition
  248. Pharmacological inhibition of EGFR signaling enhances G-CSF–induced hematopoietic Stem cell mobilization
  249. Sustained activation of mTOR pathway in embryonic neural Stem cells leads to development of tuberous sclerosis complex-associated lesions
  250. Runx1 loss minimally impacts long-term hematopoietic Stem cells
  251. Sirolimus and tacrolimus binding proteins: double-edged swords for GVHD prophylaxis
  252. In vivo selection using a cell -growth switch
  253. Mesenchymal Stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth
  254. Telomeres and Telomerase
  255. Tracking adult Stem cells
  256. The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal Stem cell niche
  257. Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
  258. Telomere biology in hematopoiesis and Stem cell transplantation
  259. Evaluation and eligibility of HLA‐identical sibling donors for Stem cell /bone marrow donation
  260. Ontogeny-related changes in proliferative potential of human hematopoietic cells.
  261. Establishment of an aging model of Sca-1+ hematopoietic Stem cell and studies on its relative biological mechanisms
  262. Modern genome-wide genetic approaches to reveal intrinsic properties of Stem cells
  263. Hematopoietic Stem cell Aging and Fate Decision
  264. Epithelial Stem cells: An epigenetic and wnt‐centric perspective
  265. Marked telomere fluctuation of leukocytes during graft-versus-host disease in allogeneic Stem cell transplantation
  266. Macrophage Inflammatory Protein-1α and Stem cell Inhibition
  267. Hematopoietic Stem cell Aging and Fate Decision
  268. Cytokine-mediated expansion does not deplete cord blood cells with Stem cell characteristics
  269. Ways of minimising hematopoietic damage induced by radiation and cytostatic drugs—the possible role of inhibitors
  270. Hematopoietic Stem cell emergence in embryonic life: developmental hematology revisited
  271. Cancer therapy-induced residual bone marrow injury: mechanisms of induction and implication for therapy
  272. Hayflick’s hypothesis: an approach to in vivo testing
  273. Expansion of LTC-ICs and Maintenance of p21 and BCL-2 Expression in Cord Blood CD34+/CD38− Early Progenitors Cultured over Human MSCs as a Feeder …
  274. Haemoprotection against cytostatic drugs by Stem cell inhibition
  275. All-trans retinoic acid induces proliferation of an irradiated Stem cell supporting stromal cell line AFT024
  276. Progress in the development of syStems for in vitro expansion of human hematopoietic Stem cells
  277. Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood Stem cell transplantation
  278. From tissue turnover to the cell of origin for pancreatic cancer
  279. Hematopoietic Stem cells: generation and self-renewal
  280. Improved outcome following allogeneic Stem cell transplantation in chronic myeloid leukemia is associated with higher expression of BMI-1 and immune …
  281. Hematopoietic progenitor/Stem cells immortalized byLhx2 generate functional hematopoietic cells in vivo
  282. Hematopoiesis from human embryonic Stem cells
  283. Current concepts in the pathophysiology and treatment of aplastic anemia
  284. Do we have to kill the last CML cell ?
  285. High‐dose therapy with peripheral blood Stem cell transplantation results in a significant reduction of the haemopoietic progenitor cell compartment
  286. cell death by sugar: Bittersweet TOR
  287. Fanconi anaemia: new strategies
  288. Aplastic anemia: pathogenesis and treatment
  289. Epigenetic modifications of Stem cells: a paradigm for the control of cardiac progenitor cells
  290. Splenic primitive hematopoietic Stem cell (PHSC) activity is enhanced by steel factor because of PHSC proliferation
  291. Stem cell factor augments tumor necrosis factor-granulocyte-macrophage colony-stimulating factor-mediated dendritic cell hematopoiesis
  292. Rapamycin and other longevity‐promoting compounds enhance the generation of mouse induced pluripotent Stem cells
  293. The microRNA cluster miR-106b~ 25 regulates adult neural Stem/progenitor cell proliferation and neuronal differentiation
  294. Stems cells and the pathways to aging and cancer
  295. The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic Stem cells
  296. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective …
  297. Polycomb silencers control cell fate, development and cancer
  298. In vivo radioprotective effect of AcSDKP on canine myelopoiesis
  299. Hypoxia-inducible factors and marrow stromal function
  300. Management of Acute Leukemia
  301. Polycomb group proteins in hematopoietic Stem cell aging and malignancies
  302. Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations
  303. Posttransplant hematopoiesis in patients undergoing sibling allogeneic Stem cell transplantation reflects that of their respective donors although with a lower functional …
  304. Hematopoietic Stem cells are not the direct target of spontaneous leukemic transformation in p18INK4C-null reconstituted mice
  305. Stonewalling Drosophila Stem cell differentiation by epigenetic controls
  306. Hematopoietic Stem cell expansion
  307. The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic Stem cells
  308. The critical role of agrin in the hematopoietic Stem cell niche
  309. Fancd2 −/− mice have hematopoietic defects that can be partially corrected by resveratrol
  310. cell cycle and developmental control of hematopoiesis by Runx1
  311. Genotoxic stress abrogates renewal of melanocyte Stem cells by triggering their differentiation
  312. Gone with the Wnt/Notch: Stem cells in laminopathies, progeria, and aging
  313. Differentiation of neural Stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2
  314. Melanocyte Stem cells
  315. Hematopoietic Stem cells and the aging hematopoietic syStem
  316. In vivo T-cell dynamics during immune reconstitution after hematopoietic Stem cell gene therapy in adenosine deaminase severe combined immune deficiency
  317. Hemopoietic Function After Use of IL-1 with
  318. Genetic Regulation of Hematopoietic Stem cell Aging
  319. Wnt Signaling in the Niche Enforces Hematopoietic Stem cell Quiescence and Is Necessary to Preserve Self-Renewal…
  320. Pathophysiologic mechanisms in acquired aplastic anemia
  321. EWS-FLI-1 expression triggers a Ewing’s sarcoma initiation program in primary human mesenchymal Stem cells
  322. Shifting senescence into quiescence by turning up p53
  323. The Wnt receptor, Lrp5, is expressed by mouse mammary Stem cells and is required to maintain the basal lineage
  324. Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic Stem cells
  325. Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible …
  326. Cellular and Molecular Crossroads of Cancer and Aging
  327. Chaotic dynamic stabilities and instabilities of hematopoietic Stem cell growth plasticity
  328. Have We Reached the Point for In Vivo Rejuvenation?
  329. Developmental plasticity of Stem cells and diseases
  330. Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways
  331. Impact papers on aging in 2009
  332. Principles of hematopoietic Stem cell biology
  333. The t (6; 9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic Stem cells for leukemogenic transformation
  334. GATA2 finds its macrophage niche
  335. Donor age and cell passage affects differentiation potential of murine bone marrow-derived Stem cells
  336. Hematopoietic Stem cells
  337. Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient in Hoxb3 and Hoxb4
  338. Roles of PPAR and p21WAF1/CIP1 in monocyte/macrophage differentiation: are circulating monocytes able to proliferate?
  339. The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blood diseases
  340. Bigger is better: maternal and neonatal predictors of hematopoietic potential of umbilical cord blood units
  341. Transcription factor Gfi1 regulates self‐renewal and engraftment of hematopoietic Stem cells
  342. Wnt/β-catenin signaling induces the aging of mesenchymal Stem cells through the DNA damage response and the p53/p21 pathway
  343. cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity
  344. Preservation of Hemopoietic Stem Cells
  345. Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression
  346. 10 Epigenetics in Cancer Stem cell Development
  347. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
  348. Blood disorders in the elderly
  349. Normal Stem cells and cancer Stem cells: similar and different
  350. Attributes of adult Stem cells
  351. Risk-adapted procedures for HSCT from alternative donor in children with severe aplastic anaemia
  352. Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults
  353. E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors
  354. Haploinsufficiency of SNEV causes defects of hematopoietic Stem cells functions
  355. The Future of Hematopoietic Growth Factors
  356. Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size
  357. Genetic marking as an approach to studying in vivo hematopoiesis: progress in the non-human primate model
  358. Standardization of hematopoietic Stem cell assays: a summary of a workshop and working group meeting sponsored by the National Heart, Lung, and Blood Institute …
  359. Identification of Stem cell transcriptional programs normally expressed in embryonic and neural Stem cells in alloreactive CD8+ T cells mediating graft-versus …
  360. Inhibitors of haemopoiesis and their potential clinical relevance
  361. Aging Stem cells, latexin and longevity
  362. Sequential sectoral conjunctival epitheliectomy (SSCE)
  363. Activation of developmental signaling pathways in hematopoietic Stem cell regeneration
  364. Somatic and germline genetics at the JAK2 locus
  365. Kinetics of normal hematopoietic Stem and progenitor cells in a Notch1-induced leukemia model
  366. Rac1 Is Required for Epithelial Stem cell Function during Dermal and Oral
  367. MicroRNA profiling reveals age-dependent differential expression of nuclear factor κB and mitogen-activated protein kinase in adipose and bone marrow …
  368. Epigenetic regulation of satellite cell activation during muscle regeneration
  369. Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome
  370. Essential biology of Stem cell transplantation
  371. Regulatory circuitries coordinated by transcription factors and microRNAs at the cornerstone of hematopoietic Stem cell self-renewal and differentiation
  372. Repopulating Activity of Ex Vivo‐Expanded Murine Hematopoietic Stem Cells Resides in the CD48−c‐Kit+Sca‐1+Lineage Marker− cell Population
  373. Retroviral expression of arginine decarboxylase attenuates oxidative burden in mouse cortical neural Stem cells
  374. A reappraisal by quantitative flow cytometry analysis of PTEN expression in acute leukemia
  375. Searching for adult Stem cells in the intestine
  376. Aging, exercise, and endothelial progenitor cell clonogenic and migratory capacity in men
  377. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary Stem cells
  378. Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic Stem cells in glioblastoma
  379. Growth factors and the molecular control of haematopoiesis
  380. BMI1 confers radioresistance to normal and cancerous neural Stem cells through recruitment of the DNA damage response machinery
  381. MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic Stem cells
  382. Chromatin modulation by oncogenic transcription factors: new complexity, new therapeutic targets
  383. Hemopoietic alterations of cancer
  384. Clinical challenges and cord blood transplantation: are we asking the right questions?
  385. Life and death in hematopoietic Stem cells
  386. The hemoregulatory peptide pEEDCK may inhibit Stem cell proliferation via hydropathic binding to antisense sequence motifs in interleukin-11 and other growth …
  387. Elucidating the role of metabolic factors in hematopoietic Stem cell maintenance
  388. Dysfunctional endothelial progenitor cells in chronic kidney disease
  389. Cancer Stem cells and aneuploid populations within developing tumors are the major determinants of tumor dormancy
  390. Telomere length and proliferation potential of hematopoietic Stem cells
  391. Age, caste, and behavior determine the replicative activity of intestinal Stem cells in honeybees (Apis mellifera L.)
  392. Replicative potential and telomere length in human skeletal muscle: implications for satellite cell -mediated gene therapy
  393. Aging and disease as modifiers of efficacy of cell therapy
  394. Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms
  395. A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells
  396. PROSPECT
  397. Differentiated cells are more efficient than adult Stem cells for cloning by somatic cell nuclear transfer
  398. Leukemia Stem Cells
  399. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
  400. Growth Factors Promote High-Dose Chemotherapy
  401. cell kinetics of CD34‐positive hematopoietic cells following chemotherapy plus colony‐stimulating factors in advanced breast cancer
  402. Aplastic Anemia & MDS International Foundation (AA&MDSIF): Bone marrow failure disease scientific symposium 2010
  403. The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications for benzene-induced hematopoietic toxicity
  404. Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation …
  405. Intratibial injection of an anti-doxorubicin monoclonal antibody prevents drug-induced myelotoxicity in mice
  406. Investigating The Role Of Runx1 In Hair Follicle Stem cell Development And Homeostasis
  407. cell cycle, CDKs and cancer: a changing paradigm
  408. Protective effects of BB-10010 treatment on chemotherapy-induced neutropenia in mice
  409. The Paton Lecture: Ocular Surface Transplantation 10 Years’ Experience
  410. Idiopathic Aplastic Anemia
  411. Mast cell growth factor enhances multilineage hematopoietic recovery in vivo following radiation-induced aplasia
  412. Growth factors and hematopoietic recovery
  413. 7 Growth inhibitors in haemopoiesis and leukaemogenesis
  414. Simultaneous knockdown of p18INK4C, p27Kip1 and MAD1 via RNA interference results in the expansion of long-term culture-initiating cells of murine bone marrow …
  415. Granulocyte colony–stimulating factor administration: adverse events
  416. Stem cells and cancer: evidence for bone marrow Stem cells in epithelial cancers
  417. Shp-2 heterozygous hematopoietic Stem cells have deficient repopulating ability due to diminished self-renewal
  418. Leukemia Stem Cells, A Pioneering Paradigmatic Model
  419. Regulation of reactive oxygen species and genomic stability in hematopoietic Stem cells
  420. mTOR: from growth signal integration to cancer, diabetes and ageing
  421. Bone marrow failure syndromes
  422. Dyskerin, telomerase and the DNA damage response
  423. The road to commitment: lineage restriction events in hematopoiesis
  424. Skeletal muscle Stem cells: effects of aging and metabolism on muscle regenerative function
  425. 22 THE NORMAL BONE MARROW AND MANAGEMENT OF TOXIN-INDUCED Stem cell FAILURE
  426. Targeting leukemia Stem cells: The new goal of therapy in adult acute myeloid leukemia
  427. Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1B β and TSLC1 in neuroblastoma
  428. cell cycle regulation in hematopoietic Stem cells
  429. HLA-matched living-related conjunctival limbal allograft for bilateral ocular surface disorders: long-term results
  430. EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
  431. Phenotypic and Functional Changes in Cord Blood Stem cell Progeny after Cytokine Activation
  432. Lentiviral gene transfer regenerates hematopoietic Stem cells in a mouse model for Mpl-deficient aplastic anemia
  433. In vitro expansion of CD34+ cells mobilized with chemotherapy and G-CSF
  434. Conditional induction of the telomerase reverse transcriptase protein and effects on Stem cell division in vivo
  435. Replicative senescence and cell immortality: the role of telomeres and telomerase
  436. Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases
  437. Same‐day determination of chimaeric status in the immediate period following allogeneic bone marrow transplantation
  438. Deletion of Puma protects hematopoietic Stem cells and confers long-term survival in response to high-dose γ-irradiation
  439. Epigenetic therapy
  440. The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
  441. Stem cells and cancer in the aerodigestive tract
  442. Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells
  443. Leukemia Stem cells and new strategies to overcome resistance to therapy
  444. PUMA kills Stem cells to stall cancer?
  445. Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features
  446. Growth factor changes in ex vivo expansion of human limbal epithelial cells on human amniotic membrane
  447. cell cycle control and check points in hematopoietic Stem cells
  448. Ovarian cancer plasticity and epigenomics in the acquisition of a Stem-like phenotype
  449. Practical Use of Hematopoietic Growth Factors in HIV Infection
  450. Novel Treatment Options
  451. Replicative senescence of mesenchymal Stem cells causes DNA-methylation changes which correlate with repressive histone marks
  452. Genetic Regulation of Hematopoietic Stem cell Numbers in Mice
  453. The biology of cancer Stem cells
  454. Self-renewal of primitive hematopoietic cells: a focus on asymmetric cell division
  455. The Tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (Goralatide) Protects From
  456. 2006 Kent Award Lecture: Is cell death and replacement a factor in aging?
  457. Transcriptional and epigenetic regulation of B cell development
  458. Cigarette Smoke Triggers Code Red: p21CIP1/WAF1/SDI1 Switches on Danger Responses in the Lung
  459. cell Cycle-Related Changes in Repopulating Capacity of Human Mobilized Peripheral Blood CD34+ Cells in Non-Obese Diabetic/Severe Combined Immune …
  460. degree of Doctor of Philosophy (Ph. D.)
  461. Research on Hutchinson-Gilford progeria syndrome
  462. TOR-driven aging: speeding car without brakes
  463. Prolonged cell Cycle Transit Is a Defining
  464. The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial …
  465. Mobilization of Peripheral Blood Stem Cells from Normal Donors
  466. Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1high leukemia cells
  467. Mobilization and transplantation of peripheral blood Stem cells
  468. The role of telomere biology in bone marrow failure and other disorders
  469. Telomere biology of human hematopoietic Stem cells
  470. Haemopoietic defect and decreased expansion potential of bone marrow autografts from patients with acute myeloid leukaemia in first remission
  471. Wnt signaling regulates hepatic metabolism
  472. Epigenetic dysregulation in cancer
  473. The DNA-damage response in human biology and disease
  474. Pharmacologic Induction of CD8+ T cell Memory: Better Living Through Chemistry
  475. Mice severely deficient in growth hormone have normal hematopoiesis
  476. Erythropoiesis in murine long‐term bone‐marrow cell cultures: Dependence on erythropoietin and endogenous production of an erythropoietic stimulating activity
  477. Mobilization of Pheripheral Blood Stem Cells from Normal Donors
  478. Empowering adult Stem cells for myocardial regeneration
  479. Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival
  480. Overview of hemopoiesis and hemopoietic reconstruction
  481. Factors that may impact on immunosenescence: an appraisal
  482. Dietary Restriction: A Model SyStem Probing the cell Fate Decision Between Cancer and Senescence
  483. Lineage-specific hematopoietic growth factors
  484. Protection from arabinofuranosylcytosine and n-mustard-induced myelotoxicity using hemoregulatory peptide pGlu-Glu-Asp-Cys-Lys monomer and dimer
  485. Modeling notch signaling in normal and neoplastic hematopoiesis: global gene expression profiling in response to activated notch expression
  486. Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic Stem cells
  487. Functional analysis of the homeobox gene HOXB4 in primitive hematopoietic cells
  488. Changing concepts in the management of severe ocular surface disease over twenty-five years
  489. TGFβ signaling in male germ cells regulates gonocyte quiescence and fertility in mice
  490. Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies
  491. Recurrence of aplastic anemia following cyclophosphamide and syngeneic bone marrow transplantation: evidence for two mechanisms of graft failure
  492. In Vitro Modifications Induced by Granulocyte-Macrophage Colony-Stimulating Factor in Human Long-Term Bone Marrow Cultures
  493. Mechanisms of Wnt-and Notch-mediated Stem cell self-renewal
  494. Cancer Stem cells: the emerging challenge of drug targeting
  495. An RbAp48-like gene regulates adult Stem cells in planarians
  496. GM-CSF multiple course priming and long-term administration in newly diagnosed acute myeloid leukemia: Comparison of three different GM-CSF routes and …
  497. Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
  498. Premeiotic germ cell defect in seminiferous tubules of Atm-null testis
  499. cell cycle regulators and hematopoiesis
  500. Quantitative analysis of mixed chimerism following allogeneic bone marrow transplantation using telomere flow-FISH
  501. Senescence and apoptosis in yeast mother cell -specific aging and in higher cells: a short review
  502. Bid is a positive regulator for donor-derived lymphoid cell regeneration in γ-irradiated recipients
  503. Peripheral blood progenitor cells versus bone marrow
  504. Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
  505. Transplante alogênico inter vivo de limbo conjuntival com pareamento HLA em doenças bilaterais da superfície ocular: resultados em longo prazo
  506. Activation of adenosine A3 receptors supports hematopoiesis-stimulating effects of granulocyte colony-stimulating factor in sublethally irradiated mice
  507. The biology and clinical uses of blood Stem cells
  508. The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic Stem cells and mature lineage progenitors by protecting from genotoxic stress
  509. Autologous and allogeneic transplantation with peripheral blood CD34+ cells: a pediatric experience
  510. Craniofacial Reconstruction and Aging of Human Mesenchymal Stem Cells
  511. Principles of hematotoxicology: laboratory assessment and interpretation of data
  512. Telomere dynamics in hematopoietic Stem cells
  513. Characterisation of the leukemic Stem cell in a murine model of CALM/AF10 positive myeloid leukemia
  514. cell aging in relation to stress arousal and cardiovascular disease risk factors
  515. Cytokine receptors, growth factors and cell cycle in human bone marrow and peripheral blood hematopoietic progenitors
  516. A low level of reactive oxygen species selects for primitive hematopoietic
  517. RUNX1 regulates the CD34 gene in haematopoietic Stem cells by mediating interactions with a distal regulatory element
  518. Norc sIGNALLING Is REQUIRED FOR
  519. Additive effect of TAp63 deficiency on the adrenocortical dysplasia (acd) phenotype
  520. Protection and selection for gene therapy in the hematopoietic syStem
  521. Genetic variation in healthy oldest-old
  522. Haemopoietic Stem cells: their heterogeneity and regulation
  523. Age-related decline in immunity: implications for vaccine responsiveness
  524. Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis
  525. Bone marrow CD34+ cells expanded on human brain endothelial cells reconstitute lethally irradiated baboons in a variable manner
  526. A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis
  527. Myelodysplastic syndrome and aplastic anemia: distinct entities or diseases linked by a common pathophysiology?
  528. Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects
  529. Mutations of mitochondrial DNA–cause or consequence of the ageing process?
  530. Efficacy of up-front 5-fluorouracil–epidoxorubicin–cyclophosphamide (FEC) chemotherapy with an increased dose of epidoxorubicin in high-risk breast cancer …
  531. Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation
  532. Adult-onset, short-term dietary restriction reduces cell senescence in mice
  533. The emerging roles of forkhead box (Fox) proteins in cancer
  534. Overexpression of Enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic …
  535. The molecular mechanisms that control thrombopoiesis
  536. Hematopoietic Effect of Fractions from the Enzyme-Digested colla corii asini on Mice with 5-Fluorouracil Induced Anemia
  537. The Wnt Receptor
  538. Stem cells for skeletal muscle repair
  539. Three-month therapeutic effect of bone marrow mesenchymal Stem cells transplantation on the treatment of X-linked muscular distrophy mice
  540. The evolution and classification of ocular surface transplantation
  541. Hematopoietic Stem Cells and Somatic Stem Cells
  542. Prospective isolation and molecular characterization of hematopoietic Stem cells with durable self-renewal potential
  543. Pseudo-DNA damage response in senescent cells
  544. Interferon-γ and tumor necrosis factor-α differentially affect cytokine expression and migration properties of mesenchymal Stem cells
  545. CDKs and CKIs: molecular targets for tissue remodelling
  546. Clonality analysis of childhood ALL in remission: no evidence of clonal hematopoiesis
  547. Aryl hydrocarbon receptor-null allele mice have hematopoietic Stem/progenitor cells with abnormal characteristics and functions
  548. Biology of bone marrow-derived endothelial cell precursors
  549. Telomere dysfunction triggers developmentally regulated germ cell apoptosis
  550. Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents
  551. Issues in the clinical development of recombinant methionyl human granulocyte colony-stimulating factor: A review
  552. Telomeres and telomerase regulation
  553. Increased longevity of hematopoiesis in continuous bone marrow cultures derived from NOS1 (nNOS, mtNOS) homozygous recombinant negative mice correlates with …
  554. Macrophage Inflammatory Protein 1α Attenuates the Toxic Effects of Temozolomide in Human Bone Marrow Granulocyte-Macrophage Colony-forming Cells
  555. Chemoprotection and selection by chemotherapy of multidrug resistance-associated protein-1 (MRP1) transduced cells
  556. Radio-and chemoprotection of bone marrow cells by opposite cell cycle-acting cytokines
  557. Lineage-specific differences in telomere length after bone marrow transplantation
  558. Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia …
  559. DNA damage and cellular differentiation: more questions than responses
  560. Granulocyte-stimulating factor and severe aplastic anemia: a survey by the European Group for Blood and Marrow Transplantation (EBMT)
  561. DNMT3b’s Role in Hematopoietic Stem Cells
  562. Opposing roles of polycomb repressive complexes in hematopoietic Stem and progenitor cells
  563. Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal
  564. Macrophage Inflammatory Protein 1 Attenuates the Toxic Effects of Temozolomide in Human Bone Marrow Granulocyte-Macrophage Colony-forming Cells1
  565. Your use of the JSTOR archive indicates your acceptance of JSTOR’s Terms and Conditions of Use, available at
  566. Accelerated wound healing by mTOR activation in genetically defined mouse models
  567. Unexpected Proatherogenic Properties of p21
  568. Autophagy and aging
  569. Cotransplantation of third-party mesenchymal stromal cells can alleviate single-donor predominance and increase engraftment from double cord transplantation
  570. The ageing epigenome: damaged beyond repair?
  571. Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling
  572. WNT signaling in adult cardiac hypertrophy and remodeling: lessons learned from cardiac development
  573. cell death in the nervous syStem
  574. In vivo haemoprotective activity of tetrapeptide AcSDKP combined with granulocyte‐colony stimulating factor following sublethal irradiation
  575. Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus
  576. A continuum model for tumour suppression
  577. Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic Stem cells
  578. Myelopoietic response in tumour-bearing mice by an aggregated polymer isolated from Aspergillus oryzae
  579. Overexpression of the MnSOD transgene product protects cryopreserved bone marrow hematopoietic progenitor cells from ionizing radiation
  580. Stimulatory effects of polar glycopeptidolipids of Mycobacterium chelonae on murine haematopoietic Stem cells and megakaryocyte progenitors
  581. EWS-FLI-1 Expression Triggers a Ewing’s Sarcoma Initiation Program in Primary Human Mesenchymal Stem Cells
  582. Microsatellite instability is not an uncommon finding in adult de novo acute myeloid leukemia
  583. Macrophages in injured skeletal muscle: a perpetuum mobile causing and limiting fibrosis, prompting or restricting resolution and regeneration
  584. Aging of the Hematopoietic SyStem
  585. Specific roles of Target of rapamycin in the control of Stem cells and their progeny in the Drosophila ovary
  586. cell senescence: the future of ageing?
  587. Circadian‐based effects of AcSDKP, with or without rhG–CSF on hematologic toxicity of chemotherapy in mice
  588. Aging-associated decline in innate immunity and therapeutic strategies to counteract it
  589. Characterization of CD62L as a marker of hematopoietic differentiation in adult mice
  590. Canonical and non-canonical Wnt signaling in hematopoiesis and lymphocyte
  591. The Role of the DNA Mismatch Repair Pathway in Adult Stem Cells In Vivo
  592. Retroviral gene therapy in hematopoietic diseases
  593. Hematopoietic Stem cells: molecular diversification and developmental interrelationships
  594. Abnormalities of axon growth in human olfactory mucosa
  595. SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells
  596. Unexpected proatherogenic properties of p21: beyond cell cycle control?
  597. Genetic modification of ex-vivo expanded Stem cells for clinical application
  598. Wnt/β-catenin signaling in normal and cancer Stem cells
  599. How transcription factors program chromatin—lessons from studies of the regulation of myeloid-specific genes
  600. Intra-articular injections in capsulitis
  601. Targeting malignant B cell self-renewal and differentiation
  602. Graft failure following allogeneic blood and marrow transplant: evidence-based nursing case study review
  603. Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model
  604. Molecular damage in cancer: an argument for mTOR-driven aging
  605. Intercellular feedback in hematopoiesis
  606. Acute myeloblastic leukemia and recombinant granulocyte colony stimulating factor.
  607. Retrospective Review of Odontogenic Infections at a Tertiary Medical Center: Clinical Correlations Based on Culture and Sensitivity Data
  608. As a matter of fat: new perspectives on the understanding of age-related bone loss
  609. Suppression of tumor suppressors in prostate cancer: the emergence of a novel oncogenic pathway
  610. Management of the hematologic manifestations of HIV disease
  611. Expression of CDK4 or CDK2 in mouse oral cavity is retained in adult pituitary with distinct effects on tumorigenesis
  612. ANALYSIS/PROSPECTS
  613. Stromal pleiotrophin regulates repopulation behavior of hematopoietic Stem cells
  614. Physiological relevance of cell cycle kinases
  615. The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs
  616. Sequential administration of interleukin-3 and granulocyte-macrophage colony-stimulating factor following intensified, accelerated CEE (cyclophosphamide …
  617. Enrichment of functionally distinct mouse hematopoietic progenitor cell populations using CD62L
  618. Beta 2 agonists and asthma.
  619. Blood progenitor cell (BPC) mobilization studied in multiple myeloma, solid tumor and non-Hodgkin’s lymphoma patients after combination chemotherapy and G-CSF
  620. Sparing of extraocular muscle in aging and muscular dystrophies: a myogenic precursor cell hypothesis
  621. Towards cure of CML: why we need to know more about CML Stem cells?
  622. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
  623. The Role of Hox Transcription Factors in the Regulation of Hematopoiesis
  624. Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science
  625. KRASG12V enhances proliferation and initiates myelomonocytic differentiation in human Stem/progenitor cells via intrinsic and extrinsic pathways
  626. The molecular basis of cutaneous aging
  627. MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β
  628. Hyaluronic acid facilitates the recovery of hematopoiesis following 5‐fluorouracil administration
  629. Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage
  630. Diabetes induced changes in rat mesenchymal Stem cells
  631. Epigenetic corruption of VDR signalling in malignancy
  632. Intra-articular injections in capsulitis
  633. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against …
  634. B-lymphocyte commitment: identifying the point of no return
  635. Effects of recombinant human granulocyte colony‐stimulating factor on leucopenia in zidovudine‐treated patients with AIDS and AIDS related complex, a phase I/II …
  636. Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA)
  637. Ex vivo culture of Fancc-/- Stem/progenitor cells predisposes cells to undergo apoptosis, and surviving Stem/progenitor cells display cytogenetic abnormalities and an …
  638. Telomere length dynamics in normal and malignant hematopoiesis
  639. Hematopoietic growth factors in transplantation: Biology and applications
  640. Reduction in the duration of myelotoxicity associated with radioimmunotherapy with infusions of the hemoregulatory peptide, HP5b in mice
  641. Recombinant human granulocyte colony-stimulating factor in the management of cancer patients: five years on
  642. Hematopoietic Stem cells
  643. Intrinsic and Microenvironmental Defects Are Involved in the Age-Related Changes of Lin−c-kit+ Hematopoietic Progenitor Cells
  644. Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles
  645. Apoptotic regulation in primitive hematopoietic precursors
  646. Theories and mechanisms of aging
  647. 11 Blood compared to marrow as a source of allogeneic hematopoietic Stem cells for
  648. RUNX1 Mutations in Clonal Myeloid Disorders: From Conventional Cytogenetics to Next Generation Sequencing, A Story 40 Years in the Making
  649. Without Hemopoietic cell Support
  650. Human somatic mutation rate estimated from SNP chips
  651. The use of hematopoietic growth factors to support cytotoxic chemotherapy for patients with breast cancer
  652. Telomere dynamics in childhood leukemia and solid tumors: a follow-up study
  653. EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence
  654. Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus
  655. The role of DNA damage and repair in aging: new approaches to an old problem
  656. Proliferation Society Meeting
  657. The polycomb gene BMI1 in normal hematopoiesis and leukemia
  658. The high functionalization of temperature-responsive culture dishes for establishing advanced cell sheet engineering
  659. Haemopoietic growth factors and dose intensity in high-grade and intermediate-grade lymphoma
  660. Eosinophils, but not neutrophils, exibit an efficient DNA repair machinary and high nucleolar activity
  661. PTEN loss in the continuum of common cancers, rare syndromes and mouse models
  662. Insulin signaling and life span
  663. Polycomb proteins in mammalian cell differentiation and plasticity
  664. The genetics of dyskeratosis congenita
  665. Stimulation of myelopoiesis in Lister a monocytogenes-infected mice by an aggregated polymer isolated from Asp ergillus oryzae
  666. High-efficiency retroviral gene transfer into murine high-proliferative-potential cells cycle-activated by cytosine arabinoside
  667. Perturbation in the ability of bone marrow stroma from patients with acute myeloid leukemia but not chronic myeloid leukemia to support normal early hematopoietic …
  668. Emerin and the nuclear lamina in muscle and cardiac disease
  669. Radiation-induced Hemopoietic and Immune Dysfunction
  670. Telomere length in Hutchinson-Gilford progeria syndrome
  671. A Randomized Phase-II Study of BB-10010 (Macrophage Inflammatory Protein-1) in Patients With Advanced Breast Cancer Receiving 5-Fluorouracil, Adriamycin …
  672. Anemia, Paroxysmal Nocturnal Hemoglobinuria, Pure Red Blood cell
  673. Cancer Initiating Cells in Head and Neck Squamous cell Carcinoma
  674. Therapy with recombinant human erythropoietin in patients with myelodysplastic syndromes
  675. XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in …
  676. An examination of ethical issues raised in the pretreatment of normal volunteer granulocyte donors with granulocyte colony-stimulating factor
  677. Telomere binding proteins including TRF1 and TRF2 (indicated by light and
  678. Granulocyte colony-stimulating factor (G-CSF) prevents dose-limiting neutropenia in lymphoma patients receiving standard dose chemotherapy
  679. Reduction in carboplatin hematopoietic toxicity in tumor bearing mice: comparative mechanisms and effects of interleukin-1β and corticosteroids
  680. Functions of Pleiotrophin in the Regulation of Hematopoiesis
  681. Therapy for Fanconi Anemia
  682. HGPS and related premature aging disorders: from genomic identification to the first therapeutic approaches
  683. Hematopoietic growth factors in cancer treatment
  684. Ku, Artemis, and ataxia-telangiectasia-mutated: signalling networks in DNA damage
  685. Defective Notch activation in microenvironment leads to myeloproliferative disease
  686. Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice
  687. The role of haemopoietic growth factors in bone marrow transplantation
  688. The role of hematopoietic growth factors in small cell lung cancer: a review
  689. Pathophysiology and treatment of acquired
  690. Recombinant human interleukin-1 receptor antagonist protects early myeloid progenitors in a murine model of cyclophosphamide-induced myelotoxicity
  691. NCI’s provocative questions on cancer: some answers to ignite discussion
  692. Regulation of senescence in cancer and aging
  693. Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress–implications for tissue and organismal aging
  694. Diffuse plasmacytosis in a child with brainStem glioma following multiagent chemotherapy and intensive growth factor support
  695. The design of differentiation therapies
  696. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone …
  697. The p38 mitogen-activated protein kinase pathway in interferon signal transduction
  698. Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration, and vasculogenesis
  699. The role of apoptosis, proliferation, and the Bcl-2–related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
  700. Telomeres and telomerase in adrenocortical tissue maintenance, carcinogenesis, and aging
  701. Identification and Characterization of Tumour Initiating Cells From Gynaecological Malignancies
  702. Pretreatment with granulocyte colony-stimulating factor reduces myelopoiesis in irradiated mice
  703. Effects of adenosine A3 receptor agonist on bone marrow granulocytic syStem in 5-fluorouracil-treated mice
  704. Biology of the Mi-2/NuRD complex in SLAC (Stemness, longevity/ageing, and cancer)
  705. Frequency Analysis of Multidrug Resistance-1 Gene Transfer into Human Primitive Hematopoietic Progenitor Cells Using the Cobblestone Area-Forming cell Assay …
  706. Epigenetic factors in cancer development: polycomb group proteins
  707. Genomic instability in incuded Stem cells and regulation of P14ARF expression
  708. Final checkup of neoplastic DNA replication: Evidence for failure in decision-making at the mitotic cell cycle checkpoint G1/S
  709. Transient monoparesis following blade plate removal in a Hutchinson-Gilford progeria syndrome patient. A case report
  710. Aging and cancer: can mTOR inhibitors kill two birds with one drug?
  711. Theoretical Paper: Exploring Overlooked Natural Mitochondria-Rejuvenative Intervention: The Puzzle of Bowhead Whales and Naked Mole Rats
  712. General introduction: Epigenetic programming by Polycomb group (PcG) proteins throughout development
  713. Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia
  714. Basic Science of Breast Cancer in Older Patients
  715. Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts
  716. TOR signaling never gets old: aging, longevity and TORC1 activity
  717. Akt signaling maintains survival and proliferation in immature T cells and hematopoietic Stem cells
  718. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
  719. CXCR4 and mobilization of hematopoietic precursors
  720. The regulation of mammary prolactin receptor metabolism by a retroviral envelope protein
  721. PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic
  722. The role of the homeobox gene Hhex in definitive hematopoietic progenitor proliferation and differentiation
  723. The importance of the telomere and telomerase syStem in hematological malignancies
  724. Anatomy and physiology of hematopoiesis
  725. Analysis of developmentally programmed changes in hematopoietic Stem cells
  726. The Role of BMP Signaling and Endoglin in Regulation of Hematopoiesis
  727. Large scale gene expression profiles of regenerating inner ear sensory epithelia
  728. Genetically determined syndromes associated with premature aging
  729. The regulation of self-renewal in hematopoietic regeneration and malignancy
  730. Dose adjustment and supportive care before and during treatment
  731. A phase I/II trial of recombinant granulocyte-macrophage colony-stimulating factor for children with aplastic anemia
  732. Gene expression profiling for adult human olfactory neuroepithelial-derived progenitors
  733. Growth-inhibiting N-substituted endogenous peptides
  734. Alpha sarcoglycan is required for FGF-dependent myogenic progenitor cell proliferation in vitro and in vivo
  735. Current status of retroviral vector mediated gene transfer into human hematopoietic Stem cells
  736. The DNA damage response: making it safe to play with knives
  737. Requirement of the transcription factor and onco-protein Gfil for the development and function of hematopoietic Stem cells and progenitor cells
  738. EZH2 is over-expressed in SCLC as a result of genomic deregulation of the Rb/E2F pathway.
  739. EZH2 depletion blocks the proliferation of colon cancer cells
  740. Identification and characterisation of novel haemopoietic gene products derived from murine embryonal Stem cells
  741. Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies
  742. Laminopathies and A-type lamin-associated signalling pathways
  743. Control of mRNA Translation in Erythropoiesis
  744. Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals
  745. The role of the transcription factor 3 gene product E47 in multipotent hematopoietic Stem cells and progenitors
  746. Therapeutic Modulation of DNA Damage and Repair Mechanisms in Blood Cells
  747. Stromal cell –immune cell interactions
  748. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis
  749. Therapy Approach of Neurodegenerative Disorders by Bone Marrow Stem Cells
  750. Aging and TOR: interwoven in the fabric of life
  751. DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies
  752. Mouse models in aging research
  753. Disposable end tidal carbon dioxide detectors.
  754. Transcription factors, chromatin and cancer
  755. T cell function in the aged: Lessons learned from animal models
  756. FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis
  757. A phase I/II trial of recombinant human interleukin‐6 in patients with aplastic anaemia
  758. Hyphal Development in Candida albicans Requires Two Temporally Linked Changes in Promoter Chromatin for Initiation and Maintenance
  759. Stress responses of human dermal fibroblasts exposed to zinc pyrithione
  760. Walking in old age and development of metabolic syndrome: the health, aging, and body composition study
  761. The latest waves in calcium signaling
  762. Leukemias: principles and practice of therapy
  763. Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy
  764. Accelerated features of age-related bone loss in zmpste24 metalloproteinase-deficient mice
  765. Embryonic senescence and laminopathies in a progeroid zebrafish model
  766. Mitochondrial ROS Generation and Its Regulation: Mechanisms Involved in H2O2 Signaling
  767. The investigation of macrophage inflammatory protein-1α as a myeloprotective agent
  768. A panel of monoclonal antibodies against human polycomb group proteins
  769. Effects of caloric restriction on cell proliferation in several tissues in mice: role of intermittent feeding
  770. The Hematopoietic Microenvironment
  771. 752Tissue Regeneration and Wound Healing
  772. Duchenne muscular dystrophy gene therapy: Lost in translation?
  773. Regulation of immune responses and hematopoiesis by the Rap1 signal
  774. Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection
  775. Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors
  776. Genetic and pharmacologic regulation of cyclin dependent kinase 4 and 6 activity in mammalian hematopoiesis
  777. Physical activity and telomere biology: exploring the link with aging-related disease prevention
  778. Hypertension, obesity, and inflammation: the complex designs of a deadly trio
  779. 13 Aging and Intrinsic Aging: Pathogenesis and Manifestations
  780. Postgraduate haematology
  781. Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo…
  782. Bridging the gap between clinical trials of antiplatelet therapies and applications among elderly patients
  783. The effect of vascular aging on cancer progression and metastasis
  784. PI3K/mTOR signaling regulates prostatic branching morphogenesis
  785. Pancytopenia and the hypocellular bone marrow
  786. Workshop on immunizations in older adults: identifying future research agendas
  787. Early Blood cell Formation
  788. The role of the histone methyltransferase egg/dSETDB1 in Drosophilia development and oogenesis
  789. Hematologic Disorders in the Elderly
  790. Fragments of functional proteins: role in endocrine regulation
  791. Cytokine regulation of hematopoietic Stem cells and lymphopoiesis
  792. Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location
  793. Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
  794. Biodegradabable [sic] endovascular stents: fulfilling the mission and then stepping away
  795. Analysis of murine mammary epithelial cellular hierarchy
  796. Chemoprotection by transfer of resistance genes
  797. Statin’s excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling
  798. Distinct Roles of Cellular Copper and Erythropoietin Receptor on Hematopoietic Engraftment
  799. Lehrstuhl für Entwicklungsgenetik
  800. The role of the TSC-mTOR pathway on the regulation of the hematopoietic Stem cells
  801. Characterization of perforin and Fas ligand effector and regulatory T cell functions in allogeneic bone marrow transplantation
  802. G1 phase control and cell differentiation
  803. The effects of physiological adaptations to calorie restriction on global cell proliferation rates
  804. Programmed cell Death and Its Role in Neurological Disease
  805. PI3K𝛅 Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic
  806. Handbook of Experimental Pharmacology
  807. Telomeres: hallmarks of radiosensitivity
  808. The role of telomerase in age-related degenerative disease and cancer
  809. Animal models of human genetic diseases: do they need to be faithful to be useful?
  810. The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity
  811. DNA Damage
  812. The Influence of MIP-1α and Its Receptors in Haemopoiesis
  813. Chromatin structure regulation in transforming growth factor-β-directed epithelial-mesenchymal transition
  814. Regulation of Stem cells and neurogenesis in the adult olfactory epithelium
  815. Identification, isolation and ex vivo expansion of haemopoietic progenitor and Stem cells
  816. Polycomb group protein Ezh2 regulates pancreas regeneration and neoplasia
  817. Mouse models for understanding the molecular mechanism of bone disease in Hutchinson-Gilford progeria syndrome
  818. Double Strand Break Signaling in Health and Diseases
  819. Bibliography Current World Literature Vol 14 No 4 July 2007
  820. CLINICAL RESEARCH PROJECT
  821. Telomere length and dynamics in Hutchinson-Gilford progeria syndrome
  822. Effects of Physiologic, Metabolic and Molecular Adaptations to Calorie Restriction on Biomarkers of Longevity
  823. Roles for E2F in mouse hematopoiesis and pancreas homeostasis
  824. 1 3 Hematopoietic Growth Factors
  825. The role of the RhoA/rho-kinase pathway in pulmonary hypertension
  826. Osteogenesis imperfecta
  827. Genomic approaches for pathway identification in regenerating sensory epithelia of the inner ear
  828. Les syndromes lipodystrophiques: des adipopathies congénitales ou acquises
  829. Nuclear lamins: major factors in the structural organization and
  830. International Workshop” From Homo sapiens to Homo sapiens liberatus
  831. cell cycle and cancer: the G1 restriction point and the G1/S transition
  832. TO ALLOMETRY AND SURVIVORSHIP
  833. The Role of CDKs in Normal and Neoplastic Proliferation
  834. Mechanisms of Gfi-1 mediated transcriptional repression
  835. Non-integrating integrase and long terminal repeat attachment site mutant HIV-1-derived lentiviral vectors
  836. Cancer Genome and DNA Repair
  837. Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
  838. hGTSE-1 Protein Unveils a New Pathway that Regulates p21CIP1/WAF1 Stability and Subcellular Localization
  839. Role of the Transcription Factor Zfx in T cell Homeostasis
  840. Phospho-regulation of the DNA Damage Response Kinase ATR
  841. Spatial, temporal and reversible regulation of endogenous genes in vivo using RNA interference
  842. Genetic studies of familial myeloproliferative disorders
  843. Accelerated aging in COPD: the relationship of telomere length and mortality in COPD
  844. Investigations of Polyamine Function Using Transgenic Mouse Models with Spermidine Synthase and S-adenosylmethionine Decarboxylase Overexpression
  845. hGTSE1 protein unveils new pathways that regulate apoptosis and cell motility
  846. DNA sequence and chromatin directed compartmentalization of chromosomal domains to the nuclear lamina
  847. Role of the MUTYH protein in the response to oxidative damage to DNA
  848. Characterisation of the role of the transcription factor Gfi-1B in haematopoiesis
  849. JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 33 (4): 474-482, 2006 UMCG Disciplinegroep: NUC Annovazzi, A., Bonanno, E., Arca, M., D’ …
  850. The effect of maternal malaria during pregnancy on birth size, early childhood growth and blood pressure in Nigerian children
  851. Macrophage Inflammatory Protein-1&alpha: An Inhibitor of Clonogenic Epidermal Keratinocyte Proliferation?
  852. CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and Stem cell exhaustion
  853. Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult Stem cell exhaustion
  854. Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic Stem cell exhaustion and development of a myeloproliferative …
  855. C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic Stem cell exhaustion
  856. Age-specific bone tumour incidence rates are governed by Stem cell exhaustion influencing the supply and demand of progenitor cells
  857. Control of the epithelial Stem cell epigenome: the shaping of epithelial Stem cell identity
  858. aPKCλ controls epidermal homeostasis and Stem cell fate through regulation of division orientation
  859. Reactive oxygen species regulate hematopoietic Stem cell self-renewal, migration and development, as well as their bone marrow microenvironment
  860. Hematopoietic Stem cell expansion: challenges and opportunities
  861. Megakaryocytes in the hematopoietic Stem cell niche
  862. Disseminated Mycobacterium Avium Infection Accelerates Hematopoietic Stem cell exhaustion
  863. C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic Stem cell exhaustion
  864. Genetic control of quiescence in hematopoietic Stem cells
  865. Akt signaling leads to Stem cell activation and promotes tumor development in epidermis
  866. Functional intestinal Stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
  867. Smurf2 regulates hematopoietic Stem cell self‐renewal and aging
  868. The intestinal crypt, a prototype Stem cell compartment
  869. Increasing Stem cell dose promotes the longevity of the graft in mice transplanted with human cord blood Stem cells
  870. Hematopoietic Stem cell Expansion, without exhaustion or Transformation, by Stable Microrna Antagonism in Vivo
  871. Cyclin E1 regulates hematopoietic Stem cell quiescence
  872. The control of hematopoietic Stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation
  873. Rapamycin increases oxidative stress response gene expression in adult Stem cells
  874. Polycomb Cbx family members mediate the balance between haematopoietic Stem cell self-renewal and differentiation
  875. PTEN expression and function in adult cancer Stem cells and prospects for therapeutic targeting
  876. 2 Age-specific bone tumour incidence rates are governed by Stem cell 3 exhaustion influencing the supply and demand of progenitor cells
  877. Relief with rapamycin: mTOR inhibition protects against radiation-induced mucositis
  878. Aging and epigenetic drift: a vicious cycle
  879. Adult Stem cells for chronic lung diseases
  880. Mechanistic links between aging and lung fibrosis
  881. miR-146a regulates hematopoietic Stem cell maintenance and cell cycle entry
  882. p57 controls adult neural Stem cell quiescence and modulates the pace of lifelong neurogenesis
  883. Hematopoietic Stem cell niche maintenance during homeostasis and regeneration
  884. The hallmarks of aging
  885. Oxymetholone Therapy of Fanconi Anemia Induces Hematopoietic Stem cell Cycling By Suppressing Osteopontin Transcription
  886. Developing a syStems-based understanding of hematopoietic Stem cell cycle control
  887. Long-term hematopoietic Stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome
  888. Epigenetics of hematopoietic Stem cell aging and disease
  889. Adult Stem cells and diseases of aging
  890. Deletion of Nono, a Novel Double-Strand Break Repair Factor, Leads to Hematopoietic Stem cell Defects
  891. Molecular regulation of Stem cell quiescence
  892. mEst1A (mouse Ever Shorter Telomeres 1A) regulates telomere length and RNA quality control in murine Stem cells
  893. DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells
  894. The Role of Innate Immune Dysfunction in Inherited Bone Marrow Failure
  895. Regulation of hematopoietic Stem cell fate by the ubiquitin proteasome syStem
  896. Concise review: Stem cell therapy for muscular dystrophies
  897. Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis
  898. Hematopoietic Stem cell expansion
  899. The transcriptional corepressorTle4 is a novel regulator of murine hematopoietic Stem and progenitor cells and their niche
  900. The hematopoietic Stem cell niche
  901. PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis
  902. MicroRNAs as mediators of the ageing process
  903. Stem cell aging: mechanisms, regulators and therapeutic opportunities
  904. Fate through fat: lipid metabolism determines Stem cell division outcome
  905. Energy metabolism and metabolic sensors in Stem cells: the metaboStem crossroads of aging and cancer
  906. Myelodysplastic syndrome-associated cytogenetic abnormalities: case report
  907. Arteriolar niches maintain haematopoietic Stem cell quiescence
  908. Regulation of Axial Stem Cells Deriving Neural and Mesodermal Tissues During Posterior Axial Elongation
  909. MicroRNA-141-3p plays a role in human mesenchymal Stem cell aging by directly targeting ZMPSTE24
  910. Metabolic plasticity and hematopoietic Stem cell biology
  911. Mouse hematopoietic Stem cell transplantation
  912. Polycomb repressive complex 2 regulates normal hematopoietic Stem cell function in a developmental-stage-specific manner
  913. Metabolic requirements for the maintenance of self-renewing Stem cells
  914. Neurogenesis in the embryonic and adult brain: same regulators, different roles
  915. Stem cell metabolism in tissue development and aging
  916. mTOR inhibition prevents epithelial Stem cell senescence and protects from radiation-induced mucositis
  917. Chronic kidney disease: a clinical model of premature aging
  918. Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
  919. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic Stem cell aging
  920. Regulation of plant Stem cell quiescence by a brassinosteroid signaling module
  921. Regulators of the proliferation of hematopoietic Stem and progenitor cells during hematopoietic regeneration
  922. Mutant U2AF1 expression alters hematopoiesis and Pre-mRNA splicing in transgenic mice
  923. Dystrophin and utrophin “double knockout” dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities
  924. Fibroblast growth factor signaling promotes physiological bone remodeling and Stem cell self-renewal
  925. The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic Stem cell self-renewal and transformation
  926. Myeloid translocation gene 16 is required for maintenance of haematopoietic Stem cell quiescence
  927. Increased Incidence of Lymphosarcoma in Long-Term Murine Survivors of Lethal Radiation: A Classification of Subtypes
  928. Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging
  929. Stem cell dynamics in Macrostomum lignano (Platyhelminthes) during homeostasis and regeneration
  930. Stem cell senescence and regenerative paradigms
  931. Induced pluripotent Stem cell model of chronic myeloid leukemia revealed olfactomedin 4 as a novel therapeutic target in leukemia Stem cells
  932. Molecular Mechanisms of Muscle Stem cell Aging
  933. Akt modes of Stem cell regulation: more than meets the eye?
  934. Chronic myeloid leukemia: the possibility of a cure
  935. Continuous clonal labeling reveals small numbers of functional Stem cells in intestinal crypts and adenomas
  936. Chromosome instability underlies hematopoietic Stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation
  937. cell cycle regulators in Stem cells
  938. Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic Stem cell function
  939. Accumulation of DNA damage-induced chromatin alterations in tissue-specific Stem cells: the driving force of aging?
  940. Serial transplantation of bone marrow to test self-renewal capacity of hematopoietic Stem cells in vivo
  941. Mimicking the functional hematopoietic Stem cell niche in vitro: recapitulation of marrow physiology by hydrogel-based three-dimensional cultures of …
  942. Transcriptional repression of Bmp2 by p21Waf1/Cip1 links quiescence to neural Stem cell maintenance
  943. A unifying hypothesis on mammalian neural Stem cell properties in the adult hippocampus
  944. Adult Hematopoietic Stem Cells: Niche Cross-Talks to Affect the cell Fate
  945. Dietary and metabolic control of Stem cell function in physiology and cancer
  946. Stem cell therapies for muscle disorders
  947. Hematopoietic Stem cell Aging and Cancer
  948. Energy metabolism and energy-sensing pathways in mammalian embryonic and adult Stem cell fate
  949. The retinoblastoma tumor suppressor and Stem cell biology
  950. Aging alters tissue resident mesenchymal Stem cell properties
  951. Hematopoietic Stem cell development: an epigenetic journey
  952. From Stem cells to cancer Stem cells: HIF takes the stage
  953. Proteostasis and aging of Stem cells
  954. Age-related cognitive decline: can neural Stem cells help us?
  955. Regulation of Hematopoietic Stem cell Fate: Self-Renewal, Quiescence and Survival
  956. Effect of Evaporative Stress on Meibomian Gland Proliferative Status and Lipid-Protein Composition
  957. Prox1 promotes expansion of the colorectal cancer Stem cell population to fuel tumor growth and ischemia resistance
  958. Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal Stem cell
  959. Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic Stem cell expansion
  960. Extracellular matrix: a dynamic microenvironment for Stem cell niche
  961. NrasG12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic Stem cell functions
  962. Adult neural Stem cells bridge their niche
  963. The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic Stem cell function
  964. Slow-cycling Stem cells in hydra contribute to head regeneration
  965. Kinase-inhibitor–insensitive cancer Stem cells in chronic myeloid leukemia
  966. Tissue-specific Stem cells: lessons from the skeletal muscle satellite cell
  967. Maintenance of leukemia-initiating cells is regulated by the CDK inhibitor Inca1
  968. Hes1 mediates the different responses of hematopoietic Stem and progenitor cells to T cell leukemic environment
  969. Age-associated alterations of pleiotropic Stem cell and the therapeutic implication of Stem cell therapy in aging
  970. Dormancy, Quiescence, and Cellular Senescence
  971. The polycomb protein Ezh2 impacts on induced pluripotent Stem cell generation
  972. Induced cancer Stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer Stem cell
  973. Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow
  974. Adult Stem cell and mesenchymal progenitor theories of aging
  975. Aged Human Cells Rejuvenated by Cytokine-Enhancement of Biomaterials for Surgical Ventricular Restoration
  976. Polycomb repressive complex 2 regulates hematopoietic Stem cell maintenance and differentiation in a developmental stage-specific manner
  977. Regenerating the skin: a task for the heterogeneous Stem cell pool and surrounding niche
  978. Fibrosis and renal aging
  979. Cdc42 and aging of hematopoietic Stem cells
  980. Deconstructing mTOR complexes in regulation of Glioblastoma Multiforme and its Stem cells
  981. Transcriptional analysis of histone deacetylase family members reveal similarities between differentiating and aging spermatogonial Stem cells
  982. Lamina-associated polypeptide (LAP) 2α and nucleoplasmic lamins in adult Stem cell regulation and disease
  983. EZH2 and KDM6A Act as an Epigenetic Switch to Regulate Mesenchymal Stem cell Lineage Specification
  984. Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia Stem cells in CML
  985. TBK1 regulates prostate cancer dormancy through mTOR inhibition
  986. Hematopoietic Stem cell Aging and Fate Decision
  987. Human ES-and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice
  988. DNA damage checkpoints in Stem cells, ageing and cancer
  989. Progerin expression disrupts critical adult Stem cell functions involved in tissue repair
  990. Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural Stem cell self-renewal and differentiation towards oligodendrocytes
  991. Absence of ductal hyper-keratinization in mouse age-related meibomian gland dysfunction (ARMGD)
  992. Defects in Glycosylation Impair Satellite Stem cell Function and Niche Composition in the Muscles of the Dystrophic Largemyd Mouse
  993. Regulation of Plant Stem cell Quiescence by a Brassinosteroid Signaling Module
  994. A stress-induced cellular aging model with postnatal neural Stem cells
  995. New Advanced Technologies in Stem cell Therapy
  996. Clonal evolution of leukemic Stem cells in a Cbx7-induced leukemia mouse model
  997. Genome-wide analysis of transcriptional regulators in human hscs reveals a densely interconnected network of coding and non-coding genes
  998. EZH2 in normal and malignant hematopoiesis
  999. Hutchinson–Gilford progeria syndrome through the lens of transcription
  1000. The impact of JAK-STAT signaling on muscle regeneration
  1001. Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation
  1002. 578 Human Blood and Cardiac Stem Cells Synergize to Enhance Cardiac Repair When Co-Transplanted Into Ischemic Myocardium
  1003. Role of the PTEN signaling pathway in autism spectrum disorder
  1004. Combined usage of Stem cells in end‐stage heart failure therapies
  1005. Bioreactor engineering of Stem cell environments
  1006. Small molecules affect human dental pulp Stem cell properties via multiple signaling pathways
  1007. Telomere biology in Stem cells and reprogramming
  1008. The analysis, roles and regulation of quiescence in hematopoietic Stem cells
  1009. Burn to cycle: energetics of cell -cycle control and Stem cell maintenance
  1010. Dual role for Insulin/TOR signaling in the control of hematopoietic progenitor maintenance in Drosophila
  1011. The PI3K/AKT signaling pathway controls the quiescence of the low‐Rhodamine123‐retention cell compartment enriched for melanoma Stem cell activity
  1012. Role of Fbxw7 in the maintenance of normal Stem cells and cancer-initiating cells
  1013. Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here
  1014. Pten deletion in adult hippocampal neural Stem/progenitor cells causes cellular abnormalities and alters neurogenesis
  1015. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
  1016. Chronic kidney disease and aging: The theme of world kidney day in 2014; nephrologist will become the professional geriatrist
  1017. Genetic rejuvenation of old muscle
  1018. Adipose-derived Stem cells: methods for isolation and applications for clinical use
  1019. The promising potential of menstrual Stem cells for antenatal diagnosis and cell therapy
  1020. An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic Stem cells
  1021. Networks Establishing Hematopoietic Stem cell Multipotency and Self-Renewal
  1022. cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
  1023. Hematopoietic Stem cells: transcriptional regulation, ex vivo expansion and clinical application
  1024. When Stemness Meets Engineering: Towards “Niche” Control of Stem cell Functions for Enhanced Cardiovascular Regeneration
  1025. Regulation of Stem cell plasticity: mechanisms and relevance to tissue biology and cancer
  1026. Lung epithelial Stem cells and their niches: Fgf10 takes center stage
  1027. Requirement for ssbp2 in hematopoietic Stem cell maintenance and stress response
  1028. Maintenance of hematopoietic Stem cells through regulation of Wnt and mTOR pathways
  1029. The Runx-PU. 1 pathway preserves normal and AML/ETO9a leukemic Stem cells
  1030. Stem cell therapy for idiopathic pulmonary fibrosis: How far are we from the bench to the bedside?
  1031. GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell , monocyte, B-and NK-cell (DCML) deficiency, and myelodysplasia
  1032. Plant and animal Stem cells: similar yet different
  1033. Drosophila follicle Stem cells are regulated by proliferation and niche adhesion as well as mitochondria and ROS
  1034. Inhibition of T cell Protein Tyrosine Phosphatase Enhances Interleukin‐18‐Dependent Hematopoietic Stem cell Expansion
  1035. Division of Rheumatology, Allergy, and Immunology
  1036. A role for RUNX1 in hematopoiesis and myeloid leukemia
  1037. The telomere syndromes
  1038. Congenital amegakaryocytic thrombocytopenia (CAMT) presenting as severe pancytopenia in the first month of life
  1039. Polycomb repressive complex 2 is required for MLL-AF9 leukemia
  1040. Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of Stem cell leukemia
  1041. Heterogeneous distribution of mechanical stress in human lung: a mathematical approach to evaluate abnormal remodeling in IPF
  1042. The regulation of signaling in hematopoietic Stem cell maintenance
  1043. Marking the tempo for myogenesis: Pax7 and the regulation of muscle Stem cell fate decisions
  1044. Umbilical cord mesenchymal Stem cell transplantation for the treatment of diabetes mellitus in rats
  1045. RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis
  1046. Satellite cells: the architects of skeletal muscle
  1047. Brief report: Blockade of Notch signaling in muscle Stem cells causes muscular dystrophic phenotype and impaired muscle regeneration
  1048. Regenerative medicine for the cornea
  1049. Methylene blue promotes quiescence of rat neural progenitor cells
  1050. Stem cells marked by the R-spondin receptor LGR5
  1051. Runx3 deficiency results in myeloproliferative disorder in aged mice
  1052. Cyclin dependent kinase inhibitors differentially modulate synergistic cytokine responsiveness of hematopoietic progenitor cells
  1053. Concurrent transient activation of Wnt/β-catenin pathway prevents radiation damage to salivary glands
  1054. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors
  1055. Caloric restriction and aging Stem cells: the stick and the carrot?
  1056. Pharmacologic Inhibition of Cardiac Stem cell Senescence
  1057. Stem cells behind the barrier
  1058. Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects
  1059. Mesenchymal Stem cell heterogeneity and ageing in vitro: A model approach
  1060. Molecular and endocrine mechanisms underlying the Stem cell theory of aging
  1061. Characterization of TLX expression in neural Stem cells and progenitor cells in adult brains
  1062. Mitochondria as signaling organelles
  1063. Injection of Vessel-Derived Stem Cells Prevents Dilated Cardiomyopathy and Promotes Angiogenesis and Endogenous Cardiac Stem cell Proliferation in mdx/utrn−/− but Not …
  1064. Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling
  1065. Muscle-derived Stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration
  1066. Stimulation of the follicular bulge LGR5+ and LGR6+ Stem cells with the gut-derived human alpha defensin 5 results in decreased bacterial presence, enhanced …
  1067. Progeroid syndromes: models for Stem cell aging?
  1068. Role of casein kinase 1A1 in the biology and targeted therapy of del (5q) MDS
  1069. A dialog on the first 20 years of PML research and the next 20 ahead
  1070. Mesenchymal Stem cells: a promising therapy for the acute respiratory distress syndrome
  1071. Human embryonic Stem cell -derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/trithorax group complexes distinctly from …
  1072. Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5
  1073. The impact of obstetric parameters on haematopoietic Stem cells extracted from the umbilical cord blood in the Chinese population
  1074. Genetic and epigenetic alterations that drive leukemic Stem cell self-renewal
  1075. Genotoxic exposure during juvenile growth of mammary gland depletes Stem cell activity and inhibits Wnt signaling
  1076. Ex vivo expanded hematopoietic Stem cells for ischemia
  1077. The role of DNA repair in the pluripotency and differentiation of human Stem cells
  1078. Telomerase exerts physiological and tumor promoting functions by stimulating ribosomal biogenesis
  1079. Changes in the frequencies of human hematopoietic Stem and progenitor cells with age and site
  1080. Aging and reprogramming: a two-way street
  1081. Geriatric muscle Stem cells switch reversible quiescence into senescence
  1082. Dystrophin-compromised sarcoglycan-δ-knockout diaphragm requires full wild-type embryonic Stem cell reconstitution for correction
  1083. Tumorigenesis in Down’s syndrome: big lessons from a small chromosome
  1084. Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis
  1085. Inhibition of Akt/mTOR attenuates age‐related changes in mesenchymal Stem cells
  1086. Neuroblastoma: Role of MYCN/Bmi1 Pathway in Neuroblastoma
  1087. Epigenetic regulation of hematopoiesis
  1088. Promises and challenges of exhausting pediatric neural cancer Stem cells
  1089. Transcriptional Quiescence of Hematopoietic Stem Cells
  1090. Longevity Pathways in Mammalian Stem Cells
  1091. Sustained Engraftment of Cryopreserved Human Bone Marrow CD34+ Cells in Young Adult NSG Mice
  1092. The diagnosis and treatment of dyskeratosis congenita: a review
  1093. MicroRNA-125 family members exert a similar role in the regulation of murine hematopoiesis
  1094. Predictive factors for successful imatinib cessation in chronic myeloid leukemia patients treated with imatinib
  1095. Suppression of replicative senescence by rapamycin in rodent embryonic cells
  1096. Geroconversion: irreversible step to cellular senescence
  1097. BM Hematopoietic Niche Occupancy Defect of HSC in Scid Mice
  1098. Embryonic Diapause as a Model for Pluripotent Stem cell Quiescence
  1099. Identification and Characterization of Cells with Stem cell Properties in Normal and Malignant Muscle Cultures
  1100. Trithorax and polycomb cooperation in MLL fusion acute leukemia
  1101. Genetic alterations of the mixed lineage leukemia
  1102. Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage
  1103. Understanding telomere diseases through analysis of patient-derived iPS cells
  1104. Bone cell senescence: mechanisms and perspectives
  1105. Cytokine combinations on the potential for ex vivo expansion of murine hematopoietic Stem cells
  1106. Spatial analysis of brassinosteroid signaling in the Stem cell niche of Arabidopsis primary root= Caracterització molecular de la funció de BRI1 en les cèl· lules mare …
  1107. Nutrient-sensing pathways and metabolic regulation in Stem cells
  1108. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration
  1109. Helen Blau: She Thinks Like a cell
  1110. Understanding The Molecular Mechanisms Of Hair Follicle Stem cell Quiescence And Genome Plasticity
  1111. Control of adult Stem cells in vivo by a dynamic physiological environment: diet‐dependent syStemic factors in Drosophila and beyond
  1112. Engineering skeletal muscle repair
  1113. Regulation of Stem cell Metabolism by the Lin28/let-7 Axis
  1114. Current concerns of undertreatment and overtreatment in chronic myeloid leukemia based on European LeukemiaNet 2013 recommendations
  1115. The Multifaceted Role of Exonuclease 1 in DNA Repair and Adult Stem cell Populations
  1116. EZH2 suppresses hepatocellular differentiation of mouse bone marrow mesenchymal Stem cells
  1117. Efficient tumorigenesis by mutation-induced failure to terminate microRNA-mediated adaptive hyperplasia
  1118. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation
  1119. Exonuclease 1 is a critical mediator of survival during DNA double strand break repair in nonquiescent hematopoietic Stem and progenitor cells
  1120. The pathogenesis of COPD and IPF: distinct horns of the same devil?
  1121. Stem cell membrane engineering: an approach for modulating cell -biomaterial interactions
  1122. Skin mirrors human aging
  1123. The cytosolic protein G0S2 maintains quiescence in hematopoietic Stem cells
  1124. ROS function in redox signaling and oxidative stress
  1125. Concise review: preleukemic Stem cells: molecular biology and clinical implications of the precursors to leukemia Stem cells
  1126. Altering Fate Determination of Human Bone Marrow-Derived Mesenchymal Stem Cells through Environmental and Transcriptional Cues
  1127. Klotho acts as a tumor suppressor in cancers
  1128. Nrf2, a regulator of the proteasome, controls self‐renewal and pluripotency in human embryonic Stem cells
  1129. Role of the p63-FoxN1 regulatory axis in thymic epithelial cell homeostasis during aging
  1130. Early forming label-retaining muscle Stem cells require p27kip1 for maintenance of the primitive state
  1131. Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer
  1132. Satellite cells, the engines of muscle repair
  1133. Transcriptional mechanisms of cell fate decisions revealed by single cell expression profiling
  1134. Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
  1135. The effect of chemotherapy on telomere dynamics: clinical results and possible mechanisms
  1136. Transcriptional control of spermatogonial maintenance and differentiation
  1137. Multifaceted aging and rapamycin
  1138. Developmental exposure to 2, 3, 7, 8 tetrachlorodibenzo-p-dioxin attenuates capacity of hematopoietic Stem cells to undergo lymphocyte differentiation
  1139. Binding to WGR domain by salidroside activates PARP1 and protects hematopoietic Stem cells from oxidative stress
  1140. From” magic bullets” to specific cancer immunotherapy
  1141. Interstitial lung disease
  1142. Evaluation of human MRC-5 cells as a feeder layer in a xenobiotic-free culture syStem for conjunctival epithelial progenitor cells
  1143. Potential of telomerase activation in extending health span and longevity
  1144. microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
  1145. Kindler syndrome in mice and men
  1146. Telomeres and age-related disease: how telomere biology informs clinical paradigms
  1147. Wnt signalling in an in vitro niche model for conjunctival progenitor cells
  1148. Adaptive inflammatory microenvironment for cell -based regeneration in ischemic cardiovascular disease
  1149. Donor satellite cell engraftment is significantlyaugmented when the host niche is preserved and endogenous satellite cells are incapacitated
  1150. MicroRNAs and epigenetics in adult neurogenesis
  1151. The Role of Polycomb Group Proteins in Hematopoietic Stem cell (HSC) Self-Renewal and Leukemogenesis
  1152. The Role of the In Vivo Microenvironment in Human Stem cell Fate Decisions
  1153. Signaling involved in hair follicle morphogenesis and development
  1154. Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo
  1155. Tissue engineered strategies for skeletal muscle injury
  1156. Genomic analysis of invasive human bone marrow derived mesenchymal Stem cells
  1157. Strange bedfellows: mitotically active chronic myeloid leukemia in molecular complete remission, detected in focal lesion of myeloma
  1158. Engraftment and lineage potential of adult hematopoietic Stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon …
  1159. Amniotic Fluid Stem Cells Restore the Muscle cell Niche in a HSA‐Cre, SmnF7/F7 Mouse Model
  1160. CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and MTOR activity determine geroconversion
  1161. www. impactaging. com AGING, July 2013, Vol. 5 No 7
  1162. Ras-proximate-1 GTPase-activating protein and Rac2 may play pivotal roles in the initial development of myelodysplastic syndrome
  1163. Mutual Reinforcement Between Telomere Capping and Canonical Wnt Pathway Activity in the Intestinal Stem cell Niche
  1164. Mouse hematopoietic cell –targeted STAT3 deletion: Stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype
  1165. Detection of paroxysmal nocturnal hemoglobinuria clones to exclude inherited bone marrow failure syndromes
  1166. Mitophagy in hematopoietic Stem cells: the case for exploration
  1167. Cdks, cyclins and CKIs: roles beyond cell cycle regulation
  1168. mTOR signaling from cellular senescence to organismal aging
  1169. mTOR signaling in growth control and disease
  1170. Stimulation of Wnt/ß-Catenin Pathway in Human CD8+ T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype
  1171. THE ROLE OF NUMB IN Stem cell HOMEOSTASIS AND BREAST TUMORIGENESIS
  1172. Possible role of autophagy activation in stimulation of regeneration
  1173. Mesenchymal Stem/stromal cells: a new”cells as drugs”paradigm. Efficacy and critical aspects in cell therapy
  1174. Skeletal muscle contractile function and neuromuscular performance in Zmpste24−/− mice, a murine model of human progeria
  1175. Mechanisms of premature cell senescence
  1176. A Wnt-TGFβ2 axis induces a fibrogenic program in muscle Stem cells from dystrophic mice
  1177. Renal Stem cells: fact or science fiction?
  1178. Intervening in ageing to prevent the diseases of ageing
  1179. The humerus of Eusthenopteron: a puzzling organization presaging the establishment of tetrapod limb bone marrow
  1180. Hematopoietic Stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress
  1181. Aufbau und Charakterisierung eines Knochenmark-Stammzellnischen-Modells Development and characterization of a bone marrow Stem cell niche model
  1182. Inducible progenitor‐derived Wingless regulates adult midgut regeneration in Drosophila
  1183. Progeria: a paradigm for translational medicine
  1184. Wnt signaling in skin development, homeostasis, and disease
  1185. Increased expression of PcG protein YY1 negatively regulates B cell development while allowing accumulation of myeloid cells and LT-HSC cells
  1186. Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin−/− mice
  1187. Adult thymic epithelium contains nonsenescent label-retaining cells
  1188. Cellular differences in protein synthesis regulate tissue homeostasis
  1189. Rescue of murine silica-induced lung injury and fibrosis by human embryonic Stem cells
  1190. Telomeres in lung diseases
  1191. The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis
  1192. Effects of microRNA-31 on skeletal muscle Stem cell self-renewal ex vivo and in vivo
  1193. Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in Stemcellness and increased …
  1194. Human TEN1 maintains telomere integrity and functions in genome-wide replication restart
  1195. The role of the aryl hydrocarbon receptor in normal and malignant B cell development
  1196. Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent Stem cells derived from FPD/AML patients
  1197. Studying aging in Drosophila
  1198. Regulation of the cyto-architecture in epithelial morphogenesis and homeostasis
  1199. What a difference a hydroxyl makes: mutant IDH,(R)-2-hydroxyglutarate, and cancer
  1200. Oncogenic Nras has bimodal effects on Stem cells that sustainably increase competitiveness
  1201. Current issues in chronic myeloid leukemia: monitoring, resistance, and functional cure
  1202. Balancing Stem cell Self-Renewal and Differentiation in the Skin
  1203. Toll-like receptor alterations in myelodysplastic syndrome
  1204. Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic Stem cells of wild type but not Id1 deficient mice
  1205. Stem Cells Propagate Their DNA by Random Segregation in the Flatworm Macrostomum lignano
  1206. Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy
  1207. Ageing Stem and progenitor cells: implications for rejuvenation of the central nervous syStem
  1208. From innate to adaptive immune response in muscular dystrophies and skeletal muscle regeneration: the role of lymphocytes
  1209. Investigation of Notch Signalling in Drosophila Germline Stem cell Niche
  1210. Graft-versus-host disease causes broad suppression of hematopoietic primitive cells and blocks megakaryocyte differentiation in a murine model
  1211. Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice
  1212. Skeletal muscle tissue engineering: which cell to use?
  1213. WISP1: Clinical insights for a proliferative and restorative member of the CCN family
  1214. Epigenetic Reprogramming in Stem Cells
  1215. Loss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscle
  1216. Metformin: do we finally have an anti-aging drug?
  1217. Brain response to calorie restriction
  1218. Modelling mammalian cellular quiescence
  1219. Current evidence that exercise can increase the number of adult Stem cells
  1220. Differential effects of epigenetic modifiers on the expansion and maintenance of human cord blood Stem/progenitor cells
  1221. www. PRSJournal. com 1159
  1222. Gerosuppression in confluent cells
  1223. The epigenetic landscape of acute myeloid leukemia
  1224. Isolation, characterization, and molecular regulation of muscle Stem cells
  1225. The Orphan Nuclear Receptor EAR-2 (NR2F6) is a Leukemia Oncogene and Novel Regulator of Hematopoietic Stem cell Homeostasis and Differentiation
  1226. Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression
  1227. Selective targeting of human colon cancer Stem-like cells by the mTOR inhibitor Torin-1
  1228. Polycomb complexes in Stem cells and embryonic development
  1229. Cardiac Stem cells: biology and clinical applications
  1230. Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow
  1231. RETRACTED: Bmi1 is critical to prevent Ikaros-mediated lymphoid priming in hematopoietic Stem cells
  1232. Cancer Stem cells and glioblastoma multiforme: Pathophysiological and clinical aspects
  1233. Gene therapy for chronic granulomatous disease: current status and future perspectives
  1234. Muscle satellite cells and duchenne muscular dystrophy
  1235. In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application
  1236. A Src family kinase–Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation
  1237. Bmi1 confers resistance to oxidative stress on hematopoietic Stem cells
  1238. The mechanistic links between proteasome activity, aging and agerelated diseases
  1239. The role of histone methyltransferase EZH2 in myelodysplastic syndromes
  1240. Skewed X-inactivation patterns in ageing healthy and myelodysplastic haematopoiesis determined by a pyrosequencing based transcriptional clonality assay
  1241. Genetic and signaling pathway regulations of tumor-initiating cells of the prostate
  1242. Triptolide inhibits histone methyltransferase EZH2 and modulates the expression of its target genes in prostate cancer cells
  1243. Pin1: a molecular orchestrator in the heart
  1244. Cdkn1b overexpression in adult mice alters the balance between genome and tissue ageing
  1245. Dept. of Laboratory Medicine and Pathology Yale University School of Medicine 330 Cedar St., New Haven, CT 06520
  1246. DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance
  1247. Host–microbiota interaction and intestinal Stem cells in chronic inflammation and colorectal cancer
  1248. Is going for cure in chronic myeloid leukemia possible and justifiable?
  1249. Transcriptional regulation of haematopoietic Stem cells
  1250. Mutations in the telomere capping complex in bone marrow failure and related syndromes
  1251. Aging Kit mutant mice develop cardiomyopathy
  1252. Advances in meniscal tissue engineering
  1253. Aging and impaired hematopoiesis
  1254. Stem Cells Propagate Their DNA by Random Segregation in the Flatworm
  1255. Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy …
  1256. Alteration of cardiac progenitor cell potency in GRMD dogs
  1257. Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model
  1258. Hutchinson-Gilford Progeria Syndrome: Pathophysiology and Possible Treatments
  1259. M (o) TOR of pseudo-hypoxic state in aging: rapamycin to the rescue
  1260. Identification and Characterization of Signaling Pathways Underlying the Tumorigenic Activity of ΔNp63α in Breast Cancer Stem Cells
  1261. The Role of STRA13 in Hematopoiesis
  1262. Answering the ultimate question “what is the proximal cause of aging?”
  1263. Journal of Aging Science
  1264. Ex vivo expansion of cord blood progenitors impairs their short‐term and long‐term repopulating activity associated with transcriptional dysregulation of signalling …
  1265. Role of mesenchymal Stem cells (MSC) in HIV-1 associated bone and lipid toxicities
  1266. Highlights of the mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology
  1267. p16INK4a protects against dysfunctional telomere–induced ATR-dependent DNA damage responses
  1268. TPP1 as a versatile player at the ends of chromosomes
  1269. High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche
  1270. Cord Blood Ex Vivo Expansion
  1271. Myelofibrosis 2012: it’s complicated
  1272. Fetal myocardium in the kidney capsule: An in vivo model of repopulation of myocytes by bone marrow cells
  1273. Mesenchymal Stem cells for therapy in lung diseases
  1274. Targeting the mTOR signaling network for Alzheimer’s disease therapy
  1275. MOZ‐Mediated Repression of p16INK4a Is Critical for the Self‐Renewal of Neural and Hematopoietic Stem Cells
  1276. MERIStem DISORGANIZATION1 Encodes TEN1, an Essential Telomere Protein That Modulates Telomerase Processivity in Arabidopsis
  1277. Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a-and Arf-independent manner
  1278. Understanding the process of fibrosis in Duchenne muscular dystrophy
  1279. Depletion of Jak2V617F myeloproliferative neoplasm-propagating Stem cells by interferon-α in a murine model of polycythemia vera
  1280. Development of approaches to improve the regenerative potential of muscle Stem cells
  1281. cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase
  1282. The role of protein clearance mechanisms in organismal ageing and age-related diseases
  1283. Muscular dystrophies share pathogenetic mechanisms with muscle sarcomas
  1284. An Opposite Effect of the CDK Inhibitor, p18INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells
  1285. Stress biology and aging mechanisms: toward understanding the deep connection between adaptation to stress and longevity
  1286. B-lineage transcription factors and cooperating gene lesions required for leukemia development
  1287. Functional Characterization of TPO‐Expanded CD34+ Cord Blood Cells Identifies CD34−CD61− Cells as Platelet‐Producing Cells Early After Transplantation in NOD/SCID …
  1288. BAF60 A, B, and Cs of muscle determination and renewal
  1289. TAP-deficient human iPS cell -derived myeloid cell lines as unlimited cell source for dendritic cell -like antigen-presenting cells
  1290. Hypoxic macrophages impair autophagy in epithelial cells through Wnt1: relevance in IBD
  1291. Murine Adipose Tissue-Derived Stromal cell Apoptosis and Susceptibility to Oxidative Stress In Vitro Are Regulated by Genetic Background
  1292. P53-participated cellular and molecular responses to irradiation are cell differentiation-determined in murine intestinal epithelium
  1293. Targeting myelogenous leukemia Stem cells: role of the circulation
  1294. Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome …
  1295. The ageing process and healthy ageing
  1296. Organelle Stress and mTOR in Aging-Associated Inflammation
  1297. The Role of UPF Proteins in Nonsense-Mediated Decay and in Neurogenesis
  1298. Aged human cells rejuvenated by cytokine enhancement of biomaterials for surgical ventricular restoration
  1299. Cheating death: does the new biology of aging show us the way?
  1300. Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic Stem cells and induces progression to myelodysplastic syndrome
  1301. The hallmarks of fibroblast ageing
  1302. Age dependence of lung mesenchymal stromal cell dynamics following pneumonectomy
  1303. The role of the Rho/Rock signaling pathway in the pathogenesis of acute ischemic myocardial fibrosis in rat models
  1304. Vascular-targeted therapies for Duchenne muscular dystrophy
  1305. Blunt-ended telomeres: an alternative ending to the replication and end protection stories
  1306. Idiopathic pulmonary fibrosis: diagnosis and prognostic evaluation
  1307. Staying alive: metabolic adaptations to quiescence
  1308. Lamins at a glance
  1309. Cord blood transplantation: can we make it better?
  1310. Accelerated aging among cancer survivors: from pediatrics to geriatrics
  1311. The chromodomain helicase Chd4 is required for Polycomb‐mediated inhibition of astroglial differentiation
  1312. The Evi5 family in cellular physiology and pathology
  1313. MicroRNA expression altered by diet: can food be medicinal?
  1314. Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia
  1315. Human umbilical cord mesenchymal Stem cells are induced in vitro to differentiate into fibroblasts
  1316. The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes
  1317. Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR)
  1318. Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin
  1319. Nestin expression in end-stage disease in dystrophin-deficient heart: implications for regeneration from endogenous cardiac Stem cells
  1320. Chromatin remodeling, DNA damage repair and aging
  1321. A nutrient-sensitive restriction point is active during retinal progenitor cell differentiation
  1322. Telomerase is required for zebrafish lifespan
  1323. Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells
  1324. Monitoring the response to tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML)
  1325. Cellular immunotherapy strategies for Ewing sarcoma
  1326. mTOR pathway in colorectal cancer: an update
  1327. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
  1328. Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita
  1329. A three-state model of telomere control over human proliferative boundaries
  1330. Life in the fast lane: mammalian disease models in the genomics era
  1331. Telomere loss in Philadelphia-negative hematopoiesis after successful treatment of chronic myeloid leukemia: evidence for premature aging of the myeloid …
  1332. Dysregulated hematopoiesis caused by mammary cancer is associated with epigenetic changes and hox gene expression in hematopoietic cells
  1333. Senescence regulation by mTOR
  1334. Self-renewal and differentiation of muscle satellite cells are regulated by the Fas-associated death domain
  1335. Stem Cells in Dystrophic Animal Models: From Preclinical to Clinical Studies
  1336. Recent progress toward epigenetic therapies: the example of mixed lineage leukemia
  1337. Physiologic hypoxia promotes maintenance of CML Stem cells despite effective BCR-ABL1 inhibition
  1338. MicroRNA 146 (Mir146) Modulates Spermatogonial Differentiation by Retinoic Acid in Mice
  1339. Epigenetic role of miRNAs in normal and leukemic hematopoiesis
  1340. Simultaneous shoulder and hip dislocation in a 12-year-old girl with Hutchinson-Gilford progeria syndrome
  1341. FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors
  1342. Epigenomics of idiopathic pulmonary fibrosis
  1343. Asymmetric Division of Damaged Proteins in Proliferating Cells
  1344. Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution
  1345. Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
  1346. Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy
  1347. Iron chelation therapy in myelodysplastic syndromes: where do we stand?
  1348. JAK of all trades: JAK2-STAT5 as novel therapeutic targets in BCR-ABL1+ chronic myeloid leukemia
  1349. The Identification and Characterization of Stem/Progenitor Cells in the Ovarian Surface Epithelium
  1350. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic Stem cells
  1351. Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI’s provocative questions
  1352. Pharmacological treatment of idiopathic pulmonary fibrosis: from the past to the future
  1353. Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
  1354. Histone methylation and aging: lessons learned from model syStems
  1355. The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells
  1356. Cellular and molecular longevity pathways: the old and the new
  1357. The Wnt/β-catenin signaling circuitry in head and neck cancer
  1358. MTG16, a target of the t (16; 21), contributes to murine lymphoid development
  1359. Ex vivo molecular rejuvenation improves the therapeutic activity of senescent human cardiac Stem cells in a mouse model of myocardial infarction
  1360. Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy
  1361. The role of chromatin modifiers in normal and malignant hematopoiesis
  1362. Gene replacement therapies for duchenne muscular dystrophy using adeno-associated viral vectors
  1363. Histone deacetylase inhibitors: a potential epigenetic treatment for Duchenne muscular dystrophy
  1364. Genetic and epigenetic control of early lymphocyte development
  1365. Cockayne syndrome b maintains neural precursor function
  1366. Epigenetic and genetic mechanisms in red cell biology
  1367. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells
  1368. Target gene regulation by PLZF in mouse undifferentiated spermatogonia
  1369. Directing Skeletal Muscle Progenitor cell Fate from Human Pluripotent Stem Cells
  1370. CST for the grand finale of telomere replication
  1371. Role of microRNAs in the age-related changes in skeletal muscle and diet or exercise interventions to promote healthy aging in humans
  1372. PKC theta ablation improves healing in a mouse model of muscular dystrophy
  1373. Maintenance and expansion of hematopoietic Stem cells in vitro using genetic methods
  1374. mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases
  1375. The effect of the Ras homolog gene family (Rho), member A/Rho associated coiled‑coil forming protein kinase pathway in atrial fibrosis of type 2 diabetes in …
  1376. Myofiber branching rather than myofiber hyperplasia contributes to muscle hypertrophy in mdx mice
  1377. An Expanding Role for Nuclear Factor κB in Muscle Stem Cells: Implications for the Treatment of Duchenne Muscular Dystrophy
  1378. Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling
  1379. Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat
  1380. Delineating molecular mechanisms of squamous tissue homeostasis and neoplasia: focus on p63
  1381. Recent developments in the treatment of Duchenne muscular dystrophy and spinal muscular atrophy
  1382. Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B
  1383. Hip pathology in Hutchinson–Gilford progeria syndrome: a report of two children
  1384. Infantile Alopecia, Characteristic Facies and Sclerosed Atrophic Limbs
  1385. Noninvasive in vivo assessment of muscle impairment in the mdx mouse model–a comparison of two common wire hanging methods with two different results
  1386. Dystrophic Changes in Extraocular Muscles after Gamma Irradiation in mdx:utrophin+/− Mice
  1387. Current management of chronic myeloid leukemia with tyrosine kinase inhibitors
  1388. Telomeres: their structure and maintenance
  1389. Hyaluronan in the healthy and malignant hematopoietic microenvironment
  1390. Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization
  1391. Single cell analyses of regulatory network perturbations using enhancer targeting TAL Effectors suggest novel roles for PU. 1 during haematopoietic specification
  1392. Microglial dysfunction in brain aging and Alzheimer’s disease
  1393. Wnt/β-catenin pathway in bone cancers
  1394. RUNX1 meets MLL: epigenetic regulation of hematopoiesis by two leukemia genes
  1395. Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer
  1396. Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
  1397. Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling …
  1398. Ageing and the border between health and disease
  1399. Cellular polarity in aging: role of redox regulation and nutrition
  1400. Exploiting tumor cell senescence in anticancer therapy
  1401. NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas
  1402. Bone tissue and muscle dystrophin deficiency in mdx mice
  1403. Plasticity of salamander skeletal muscle cells
  1404. Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H
  1405. Grafting of a single donor myofibre promotes hypertrophy in dystrophic mouse muscle
  1406. Telomeropathies: An emerging spectrum disorder
  1407. Defining the mechanism of prostaglandin E2- Enhanced hematopoietic Stem and progenitor cell homing
  1408. Selected clinical highlights from the 2012 ERS congress in Vienna
  1409. Epigenomic programing: a future way to health?
  1410. Reduced IGF signaling prevents muscle cell death in a Caenorhabditis elegans model of muscular dystrophy
  1411. The role of epigenetic modifiers in hematopoiesis
  1412. Human CST abundance determines recovery from diverse forms of DNA damage and replication stress
  1413. Aplastic anaemia: pathophysiology, care and management
  1414. The lilliputians and the giant: an emerging oncogenic microRNA network that suppresses the PTEN tumor suppressor in vivo
  1415. Graft-versus-host disease causes broad suppression of hematopoietic 2 primitive cells and block in megakaryocyte differentiation in a murine 3 model 4
  1416. The emerging roles of AhR in physiology and immunity
  1417. The c-Jun N-terminal Kinases (JNK)/Mitogen-activated Protein Kinase (MAPK) is Responsible for the Protection of Tanshinol (Danshensu) upon H 2 O 2 …
  1418. Ubiquitination and the Ubiquitin–Proteasome SyStem as regulators of transcription and transcription factorsin epithelial mesenchymal transition of cancer
  1419. A review of current and novel therapies for idiopathic pulmonary fibrosis
  1420. Understanding nucleotide excision repair and its roles in cancer and ageing
  1421. Ontology of Aging
  1422. Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy
  1423. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
  1424. Regulation of neural precursor self-renewal via E2F3-dependent transcriptional control of EZH2
  1425. Conversations with pioneers in the bone field: Stavros C Manolagas
  1426. Premature aging syndrome
  1427. Geriatric population and relevant contemplation
  1428. Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis
  1429. High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of
  1430. CT-0507 Accepted 10/21/2011 for publication in “cell Transplantation” Alteration of cardiac progenitor cell potency in GRMD dogs
  1431. Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions
  1432. Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL
  1433. Insights into skeletal muscle development and applications in regenerative medicine
  1434. Idiopathische pulmonale Fibrose: Diagnostik und prognostische Beurteilung
  1435. Mammalian target of rapamycin signaling in cardiac physiology and disease
  1436. Enhancer of zeste homolog 2 is a negative regulator of mitochondria-mediated innate immune responses
  1437. Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification
  1438. Pharmacologic Profiling of Phosphoinositide 3-Kinase Inhibitors as Mitigators of Ionizing Radiation–Induced cell Death
  1439. Pirfenidone for the treatment of idiopathic pulmonary fibrosis
  1440. l-Leucine Alters Pancreatic β-cell Differentiation and Function via the mTor Signaling Pathway
  1441. The human CST complex is a terminator of telomerase activity
  1442. Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication
  1443. The biology of telomeres in multipotential stromal cells
  1444. Current status of idiopathic nonspecific interstitial pneumonia
  1445. Calorie restriction and NAD+/sirtuin counteract the hallmarks of aging
  1446. Aging of the brain, dementias, role of infectious proteins: facts and theories
  1447. The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease
  1448. Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma
  1449. Inflammation in Muscle Repair, Aging, and Myopathies
  1450. Genetically engineered mouse models of human B-cell precursor leukemias
  1451. Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle
  1452. Role of oxidative stress and telomerase on haematopoietic Stem and progenitor cell ageing
  1453. Loss of telomere protection: consequences and opportunities
  1454. Molecular basis of telomere syndrome caused by CTC1 mutations
  1455. Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications
  1456. Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects
  1457. Intermittent Hypoxia and Health: From Evolutionary Aspects to Mitochondria Rejuvenation
  1458. Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in
  1459. Hyperactivated Wnt signaling induces synthetic lethal interaction with Rb inactivation by elevating TORC1 activities
  1460. The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability
  1461. RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells
  1462. Alive and well? Exploring disease by studying lifespan
  1463. Anti-aging effects of Ketanserin; Ketanserin extends lifespan in female drosophila, inhibits cellular senescence and promotes wound healing in-vitro
  1464. A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis
  1465. Identifying and validating a combined mRNA and microRNA signature in response to imatinib treatment in a chronic myeloid leukemia cell line
  1466. Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs
  1467. Regenerative strategies for craniofacial disorders
  1468. Analysis of Poly(ADP-Ribose) Polymerases in Arabidopsis Telomere Biology
  1469. Transcriptional and Epigenetic Regulation in the Development of Myeloid Cells: Normal and Diseased Myelopoiesis
  1470. Murine models of dysfunctional telomeres and telomerase
  1471. Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders
  1472. Mammalian target of rapamycin and the kidney. I. The signaling pathway
  1473. Emerging drugs for polycythemia vera
  1474. The Role of the E47-p21 Pathway in Long-Term Hematopoietic Stem Cells During Homeostasis and Under Repopulation Stress
  1475. Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein
  1476. Distinct transforming activity of ABL family tyrosine kinase oncogenes is induced by their C-terminal domain
  1477. Cdc13 at a crossroads of telomerase action
  1478. MURINE DYSFUNCTIONAL MODELS OF TELOMERES AND TELOMERASE
  1479. NCI’s provocative questions on cancer: some answers to ignite
  1480. In vivo behaviour of human precursors into a dystrophic context
  1481. POT1a and Components of CST Engage Telomerase and Regulate Its Activity in Arabidopsis
  1482. Detection and quantification of extracellular microRNAs in murine biofluids
  1483. Animal models of duchenne muscular dystrophy, with special reference to the mdx mouse
  1484. Cutting through the complexities of mTOR for the treatment of stroke
  1485. CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis
  1486. Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases
  1487. Targeting the cell Cycle for Cancer Treatment and Neuroprotection
  1488. Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging
  1489. WNT7B promotes bone formation in part through mTORC1
  1490. BioMed Research International
  1491. Smoking accelerates aging of the small airway epithelium
  1492. SOX2 is critical for the maintenance of quiescence and homeostasis in nascent Müller glial cells
  1493. Network medicine, multimorbidity and the lung in the elderly
  1494. 20 CHAPTER Childhood Muscular Dystrophies
  1495. THE ROLE OF WNTS IN ADULT MURINE HEMATOPOIESIS AND INTESTINAL HOMEOSTASIS
  1496. The CDK network: linking cycles of cell division and gene expression
  1497. New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses
  1498. TUMOR BURDEN INDUCES A SELF-AMPLIFYING LOOP OF MYELOPOIESIS
  1499. RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement
  1500. Cellular Senescence and Premature Aging in Lung Diseases
  1501. Linking cytoarchitecture to metabolism: sarcolemma-associated plectin affects glucose uptake by destabilizing microtubule networks in mdx myofibers
  1502. Intermittent Hypoxia and Health: From Evolutionary Aspects
  1503. Organization and evolution of Drosophila terminin: similarities and differences between Drosophila and human telomeres
  1504. Runx Family Genes in a Cartilaginous Fish, the Elephant Shark (Callorhinchus milii)
  1505. DNA repair at telomeres: keeping the ends intact
  1506. Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targeting
  1507. Replication of telomeres and the regulation of telomerase
  1508. The aryl hydrocarbon receptor nuclear translocator (ARNT) modulates the antioxidant response in AML cells
  1509. The Detection of Progerin Expression in Mammals
  1510. Identification of Novel HIF1A Target Genes That Regulate Tumor Progression and Metastasis
  1511. Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: what can be learned from hematologic malignancies?
  1512. Congenital vulnerability of cutaneous segments arising from skin mosaicism: A genetic basis for locus minoris resistentiae
  1513. Comparative genomics of X-linked muscular dystrophies: the golden retriever model
  1514. Current Issues in Chronic Myeloid Leukemia: Monitoring, Resistance, and Functional Cure
  1515. Regulation of the hematopoietic self-renewal and lineage choice: role of Pbx1 and micro-RNAs
  1516. Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer
  1517. Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression
  1518. A Surrogate mRNA-Based Single cell Assay for Rapidly Enumerating Rare Long-Term Hematopoietic Stem Cells
  1519. Sexual dimorphism in the early embryogenesis in zebra finches
  1520. T cells development in vitro: a minimalist approach
  1521. Growth phase-dependent roles of Sir2 in oxidative stress resistance and chronological lifespan in yeast
  1522. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and …
  1523. Immunopathogenesis of Primary Cicatricial Alopecia
  1524. The THO complex component Thp2 counteracts telomeric R‐loops and telomere shortening
  1525. HOT1 is a mammalian direct telomere repeat‐binding protein contributing to telomerase recruitment
  1526. Anti-aging effects of the Transcendental Meditation Program: Analysis of ojas level and global gene expression
  1527. A Highlights from MBoC Selection: Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle
  1528. Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging
  1529. Characterization of RUNX1 function in hematopoiesis
  1530. Human CST has independent functions during telomere duplex replication and C-strand fill-in
  1531. TGF-β signaling in Duchenne muscular dystrophy
  1532. The GH/IGF-1 axis in ageing and longevity
  1533. A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression
  1534. A Novel Response to Cellular Hypoxia Increases Lifespan in C. elegans
  1535. Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres
  1536. Beyond telomerase: Telomere instability as a novel target for cancer therapy
  1537. Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis
  1538. DNA Damage Response and Replication Stress in Mouse Embryonic Stem Cells
  1539. NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
  1540. Myc-mediated transcription control of SAE1 and PUMA loci in cancer and reprogramming
  1541. Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts
  1542. Mammalian DNA2 helicase/nuclease cleaves G‐quadruplex DNA and is required for telomere integrity
  1543. Hematopoietic syStem
  1544. EXPLOITING VASOPRESSIN SIGNALLING IN MUSCULAR ATROPHY AND DYSTROPHIES
  1545. Hutchison-Gilford Progeria Syndrome–A new treatment strategy and the role of prelamin A in oncogenesis
  1546. Regulation of DNA damage responses by ubiquitin and SUMO
  1547. mTOR signaling in cardiac physiology and disease: Sciarretta et al. mTOR signaling in the cardiovascular syStem
  1548. Non-coding RNAs in cardiovascular ageing
  1549. The size–life span trade-off decomposed: why large dogs die young
  1550. Idiopathic Pulmonary Fibrosis: Treatment Strategies
  1551. MMP-7 and fcDNA serum levels in early NSCLC and idiopathic interstitial pneumonia: preliminary study
  1552. Structure of the human telomeric Stn1-Ten1 capping complex
  1553. Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity
  1554. The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch
  1555. Role of Setbp1 in Myeloid Leukemia Development
  1556. Telomere-end processing: mechanisms and regulation
  1557. CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase
  1558. General Transcription Factors and Embryonic Genome Activation
  1559. Persistent GATA2 expression promotes self-renewal of myeloid progenitors and blocks lymphoid differentiation
  1560. Functional Analysis of ACD Mutations in Dyskeratosis Congenita.
  1561. Characterization of the Runx Gene Family in a Jawless Vertebrate, the Japanese Lamprey (Lethenteron japonicum)
  1562. DNA Damage Response and Replication Stress in Mouse Embryonic Stem Cells
  1563. Role of the neurotrophic factor receptor RET in haematopoiesis
  1564. From signal transduction to targeted therapy: interference with TGF-β and myostatin signaling for Duchenne muscular dystrophy Date: 2012-10-16
  1565. Double bromodomain proteins as regulators of lymphopoiesis and inflammation
  1566. From signal transduction to targeted therapy: interference with TGF-_ and myostatin signaling for Duchenne muscular dystrophy
  1567. Clinical highlights from the 2011 ERS Congress in Amsterdam
  1568. Structural and functional association of androgen receptor with telomeres in prostate cancer cells
  1569. Impact of Gestational Exposure to 2, 3, 7, 8-Tetrachlorodibenzo-P-Dioxin on T Lymphocyte Development
  1570. Comparação do potencial terapêutico de células mesenquimais e pericitos em modelo murino de distrofia muscular
  1571. Effects of Heregulin on Muscle: A Biochemical and Histological Analysis
  1572. A paper in print at the Journal of the Federation of American Societies for Experimental Biology3
  1573. Pathways Disturbed in Duchenne Muscular Dystrophy
  1574. Contribution of the GATA2 transcription factor to the development and progression of myeloid disorders
  1575. Idiopathic pulmonary fibrosis may be a disease of recurrent, tractional injury to the periphery of the aging lung: a unifying hypothesis regarding etiology and …
  1576. Isolation of primary canine satellite cells
  1577. Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and …
  1578. A chromatin-modifying protein is a context-dependent modulator of cell survival in hematopoietic malignancies
  1579. ESGCT and NVGCT Collaborative Congress: The Hague-23 to 26 October Abstracts
  1580. Artemis C-terminal region facilitates V (D) J recombination through its interactions with DNA Ligase IV and DNA-PKcs
  1581. The dynamic behavior and cellular evolution of multilineage leukemias induced by the Polycomb group protein Cbx7
  1582. MicroRNAs expression profiles in cardiovascular diseases
  1583. Lipid replacement therapy: a natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function
  1584. A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog …
  1585. The effects of mammary tumours on hematopoiesis and dendritic cell development
  1586. The impact of MAO-A in cellular senescence
  1587. The genetic pleiotropy of musculoskeletal aging
  1588. If the cap fits, wear it: an overview of telomeric structures over evolution
  1589. The Role of microRNA miR-101 in Prostate Cancer Progression
  1590. Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and …
  1591. Characterization of the putative CALM/AF10 collaborator Meis1 in leukemia development
  1592. A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16
  1593. Regulation of early B cell development by Flt3 signaling
  1594. Dissecting the epigenetic landscapes of hematopoiesis and fission yeast.
  1595. Pbx1-directed transcriptional regulation of mural cell differentiation and vascular patterning in the developing kidney and spleen
  1596. Why Do Vaccines Fail the Elderly?
  1597. Consequences of endogenous mitochondrial oxidative stress in the heart
  1598. Genome-Wide Loss-of-Function Genetic Screens Identify Novel Senescence Genes and Putative Tumor Suppressors
  1599. Chemical genetic analyses of quantitative changes in Cdk1 activity during the human cell cycle
  1600. A mechanistic examination of the inhibitory role of cyclic AMP signaling on megakaryocytic differentiation
  1601. Regulation of the Ran GTPase SyStem and Nucleocytoplasmic Transport
  1602. Mediators and markers of mammalian lifespan extension: Proteomic, proliferative and hormonal adaptations in mouse models of extended lifespan
  1603. A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and
  1604. Dissection of the telomere complex CST in Arabidopsis thaliana
  1605. Evaluating the PGC-1 alpha pathway and a new preclinical model to advance treatment options for dystrophinopathies
  1606. The Rho-GAP GRAF1 Regulates Skeletal Muscle Maturation and Repair
  1607. Defining the Sequence Elements and Candidate Genes for the Coloboma Mutation
  1608. NEUROTROPHIN RECEPTOR P75NTR AND ITS LIGAND BDNF IN HUMAN SKELETAL MUSCLE: INVOLVEMENT IN MYOGENESIS AND MUSCLE REPAIR
  1609. Dose-thresholds for alpha-radiation induced cancer risk: absence of risk following small alpha-emitting radionuclide intakes
  1610. THE INTERPLAY BETWEEN RUNX3 AND TEAD-YAP COMPLEX IN GASTRIC CANCER
  1611. CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point
  1612. Endothelial progenitor cells as biomarkers for cardiovascular risk
  1613. REACTIVE OXYGEN SPECIES AND TELOMERE DYSFUNCTION: INVESTIGATING THE UNDERLYING MECHANISMS OF AGING AND RELATED DISEASES
  1614. Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE progeroid syndrome
  1615. Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner
  1616. Discussion of “Biomedical Infor-matics: We Are What We Publish”
  1617. Novel mechanisms of transcriptional regulation by leukemia fusion proteins
  1618. The metabolic syndrome and HIV infection
  1619. On the Phenotype of White-tailed Deer Antlerogenic Progenitor Cells.
  1620. Isolation and characterization of human endothelial colony forming cells (ECFCs) and effect of oxidative stress on their differentiation
  1621. Telomere and proximal sequence analysis using high-throughput sequencing reads
  1622. Relationship of individual pilot factors to simulated flight performance
  1623. Alternative splicing by hnRNP L as a new regulator of hematopoietic cell development, survival and migration
  1624. NLRC3 is a negative regulator of DNA-induced immune response
  1625. Discussion of “Biomedical informatics: We are what we publish”
  1626. Structural and Functional Analysis of mTORB
  1627. Measurement of Bone Translations and Sarcomere Lengths in Humans Using Novel Optical SyStems
  1628. TYPE IInterferons IN SYStemIC LUPUS ERYTHEMATOSUS
  1629. Differential functions of mammalian Cdk7 and CCRK kinases in regulating transcription and ciliogenesis
  1630. Structural, functional and genomic changes associated to aging in the liver of rats fed life-long on virgin olive, sunflower or fish oils, as dietary fats
  1631. Regulation of eukaryotic transcription by bHLH/PAS transcription factors AhR and Arnt.
  1632. Circadian regulation of mTOR signaling via BMAL1 dependent mechanism
  1633. Theories and mechanisms of aging
  1634. Cyclin D: Cdk4/6 Complexes Activate Rb by Mono-Phosphorylation
  1635. Small Molecule Modulators of Dauer Formation and Longevity in Caenorhabditis Elegans
  1636. Direct Assessment of Respiratory and Cardiac Function and Reserve Capacity in a Large Animal Model of Duchenne Muscular Dystrophy.
  1637. Age-related effects on the mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in breast cancer and the characterization of novel MEK5 …
  1638. Control of the G1/S Transition of the cell Cycle by the CDK Activating Kinase, Cdk7
  1639. A co-translational ubiquitination pathway for quality control of newly synthesized proteins
  1640. The role of the polyadenylation site of the melanocortin 1 receptor in generating MC1R-TUBB3 chimeras, And, Attenuation of TORC1 delays the onset of …
  1641. Sepsis induces hematopoietic Stem cell exhaustion and myelosuppression through distinct contributions of TRIF and MYD88
  1642. CXCR4/CXCL12 axis counteracts hematopoietic Stem cell exhaustion through selective protection against oxidative stress
  1643. Metabolism and the control of cell fate decisions and Stem cell renewal
  1644. Hematopoietic Stem cell exhaustion and advanced glycation end-products in the unexplained anemia of the elderly
  1645. Stem cells and aging
  1646. … of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem cell exhaustion and Accelerates JAK2V617F …
  1647. Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic Stem cell cycling
  1648. Rejuvenating muscle Stem cell function: restoring quiescence and overcoming senescence
  1649. Stem cell depletion by global disorganization of the H3K9me3 epigenetic marker in aging
  1650. Chronic Infection Drives Hematopoietic Stem cell exhaustion through Differentiation and a Lowered Threshold for Apoptosis
  1651. … : Mesenchymal Stem Cells From Idiopathic Pulmonary Fibrosis Patients Display Signs Of Senescence Leading To Stem cell exhaustion That May Result In Lower …
  1652. Inactivation of a Gαs–PKA tumour suppressor pathway in skin Stem cells initiates basal-cell carcinogenesis
  1653. Chemotherapy and Stem cell transplantation increase p16INK4a expression, a biomarker of T-cell aging
  1654. Neural Stem cells and nutrients: poised between quiescence and exhaustion
  1655. From “traction bronchiectasis” to honeycombing in idiopathic pulmonary fibrosis: a spectrum of bronchiolar remodeling also in radiology?
  1656. Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal Stem cells
  1657. Novel chemical attempts at ex vivo hematopoietic Stem cell expansion
  1658. Defining the general principles of Stem cell aging: lessons from organismal models
  1659. Cbfb deficiency results in differentiation blocks and Stem/progenitor cell expansion in hematopoiesis
  1660. Dok1 and Dok2 proteins regulate cell cycle in hematopoietic Stem and progenitor cells
  1661. Stem cell maintenance: aMPLe splicing choices
  1662. Metabolic regulation of Stem cell function in tissue homeostasis and organismal ageing
  1663. The ubiquitin ligase HUWE1 regulates hematopoietic Stem cell maintenance and lymphoid commitment
  1664. Decoding the RNA Editome of Normal Versus Malignant Progenitor cell Aging Short Title: RNA Editing in Normal Aging and MDS/AML Stem Cells
  1665. RNA processing signatures of normal versus malignant progenitor cell aging predict leukemia Stem cell sensitivity to RNA splicing modulation
  1666. Accelerated ageing of the lung in COPD: new concepts
  1667. An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic Stem cell fate
  1668. Molecular mechanisms of normal and pathological aging
  1669. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic Stem cells
  1670. Fancb deficiency impairs hematopoietic Stem cell function
  1671. Ultraviolet radiation-induced skin aging: the role of DNA damage and oxidative stress in epidermal Stem cell damage mediated skin aging
  1672. Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model
  1673. Stem cell aging and sex: are we missing something?
  1674. The PCL1-p53 axis promotes cellular quiescence
  1675. WNT signaling in lung aging and disease
  1676. Declined presentation PRMT5 methyltransferase activity is required to sustain adult hematopoiesis
  1677. The syStemic milieu as a mediator of dietary influence on Stem cell function during ageing
  1678. Telomere dysfunction causes alveolar Stem cell failure
  1679. Wnt signalling meets epigenetics
  1680. Aneuploidy impairs hematopoietic Stem cell fitness and is selected against in regenerating tissues in vivo
  1681. The aging population: demographics and the biology of aging
  1682. Pilot Study of Prognostic Impact of Pre-Allogeneic Hematopoietic cell Transplantation (HCT) Plasma Levels of CXC-Chemokines (CXCL-4 and CXCL-7) in …
  1683. Targeting muscle Stem cell intrinsic defects to treat Duchenne muscular dystrophy
  1684. Neuropeptide Y: an anti-aging player?
  1685. Adult muscle Stem cell isolation
  1686. Aging and pulmonary fibrosis
  1687. Stem cell mitochondria during aging
  1688. Aging and kidney disease.
  1689. Optimization of reference genes for normalization of reverse transcription quantitative real-time polymerase chain reaction results in senescence study of …
  1690. Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
  1691. Chemotherapy and Stem cell Transplantation Increase p16INK4a Expression, a Biomarker of T-cell Aging
  1692. Metabolic regulation of hematopoietic Stem cell commitment and erythroid differentiation
  1693. Increased gene dosage of Ink4/Arf and p53 delays age‐associated central nervous syStem functional decline
  1694. TCDD-induced activation of aryl hydrocarbon receptor regulates the skin Stem cell population
  1695. When Stem cells grow old: phenotypes and mechanisms of Stem cell aging
  1696. Aryl hydrocarbon receptor deficiency in an exon 3 deletion mouse model promotes hematopoietic Stem cell proliferation and impacts endosteal niche cells
  1697. Identifying Micrornas that Regulate Aging of the Germline Stem cell Niche
  1698. Mechanisms of development of multimorbidity in the elderly
  1699. Epigenetic control of adult Stem cell function
  1700. Deubiquitinase MYSM1 is essential for normal bone formation and mesenchymal Stem cell differentiation
  1701. Regulation of skeletal muscle Stem cell quiescence by Suv4-20h1-dependent facultative heterochromatin formation
  1702. miR‐152 induces human dental pulp Stem cell senescence by inhibiting SIRT 7 expression
  1703. The role of mitochondrial dysfunction in age-related diseases
  1704. Hutchinson–Gilford progeria syndrome as a model for vascular aging
  1705. iPSCs-based anti-aging therapies: Recent discoveries and future challenges
  1706. 282. Circumventing Hematopoietic Toxicities and Reversing Sickle Phenotype by Lineage-Specific BCL11A Knock Down and γ-Globin Induction
  1707. G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy
  1708. Progeria accelerates adult Stem cell aging
  1709. 283. In Vivo Selection of MGMT (P140K) Gene Modified Hematopoietic Cells in the Nonhuman Primate Unmasks a Dormant Pool of Repopulating Clones with …
  1710. Molecular and biological hallmarks of ageing
  1711. As “SIRT” ing the role of an epigenetic modifier in hematopoietic Stem cell homeostasis
  1712. A rat treated with mesenchymal Stem cells lives to 44 months of age
  1713. Loss of Folliculin Disrupts Hematopoietic Stem cell Quiescence and Homeostasis Resulting in Bone Marrow Failure
  1714. Natural (tryptophan) metabolites—mediated activation of aryl hydrocarbon receptor inhibits cancer Stem cell signaling: what does it mean to prevent cancer …
  1715. DDIT4 regulates mesenchymal Stem cell fate by mediating between HIF1α and mTOR signalling
  1716. Leukemic Stem Cells S (p) liced Off
  1717. Molecular regulation of muscle Stem cell asymmetric division
  1718. NucleoStemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging
  1719. SOX17 is critical for the maintenance of Stem cell phenotype of intra-aortic hematopoietic clusters of cells in the aorta-gonad-mesonephros region
  1720. Innate immune signaling and Stem cell renewal in idiopathic pulmonary fibrosis
  1721. Suppression of Luteinizing Hormone Enhances HSC Recovery after Hematopoietic Injuries
  1722. Abstract PR06: Mutant U2AF1 alters hematopoiesis and pre-mRNA splicing in transgenic mice.
  1723. The APC/C Coactivator Cdh1 Controls Self-Renewal and Differentiation of Human and Murine HSPCs
  1724. The central role of muscle Stem cells in regenerative failure with aging
  1725. Tissue-specific designs of Stem cell hierarchies
  1726. Determinants of frailty and longevity: are they the same ones?
  1727. Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position
  1728. Autophagy: a decisive process for Stemness
  1729. Genome integrity in aging: human syndromes, mouse models, and therapeutic options
  1730. High levels of canonical Wnt signaling lead to loss of Stemness and increased differentiation in hematopoietic Stem cells
  1731. Rationale and design of the allogeneiC human mesenchymal Stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A …
  1732. Decoding the Stem cell quiescence cycle–lessons from yeast for regenerative biology
  1733. cell cycle regulation of hematopoietic Stem or progenitor cells
  1734. Epigenetic control of Stem cell potential during homeostasis, aging, and disease
  1735. Unmanipulated haploidentical haematopoietic Stem cell transplantation for children with severe aplastic anaemia
  1736. Role of lncRNAs in cellular aging
  1737. cell hierarchies in colorectal cancer: focus on APC and BRAF
  1738. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic Stem cell ex vivo expansion
  1739. Adult thymic epithelial cell (TEC) progenitors and TEC Stem cells: Models and mechanisms for TEC development and maintenance
  1740. Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal Stem cell differentiation
  1741. The basic principles of Stem cells
  1742. Quantitative analysis of male germline Stem cell differentiation reveals a role for the p53-mTORC1 pathway in spermatogonial maintenance
  1743. Polycomb repressive complex 2 component Suz12 is required for hematopoietic Stem cell function and lymphopoiesis
  1744. Evidence that hematopoietic Stem cell function is preserved during aging in long-lived S6K1 mutant mice
  1745. Hallmarks of the ageing lung
  1746. Deciphering Metabolic Regulation of Hematopoietic Stem cell Fate
  1747. Mechanism of Functional Alterations in Hematopoietic Stem cell Aging
  1748. ICRP publication 131: Stem cell biology with respect to carcinogenesis aspects of radiological protection
  1749. Insulin-like growth factor 2 modulates murine hematopoietic Stem cell maintenance through upregulation of p57
  1750. MLL-AF9–and HOXA9-mediated acute myeloid leukemia Stem cell self-renewal requires JMJD1C
  1751. Autophagy maintains Stemness by preventing senescence
  1752. Effects of senescent lens epithelial cells on the severity of age-related cortical cataract in humans: A case–control study
  1753. Role of Stem cell Therapy in Treatment of Muscular Dystrophy
  1754. Potential links between tendon pathology and platelet rich plasma biology
  1755. The Role of Stem cell Genomic Instability in Aging
  1756. SIRT6 safeguards human mesenchymal Stem cells from oxidative stress by coactivating NRF2
  1757. Olive oil and the hallmarks of aging
  1758. A muscle Stem cell for every muscle: variability of satellite cell biology among different muscle groups
  1759. Naive T cell maintenance and function in human aging
  1760. Epigenetic control of adult skeletal muscle Stem cell functions
  1761. Therapeutic potential of mTOR inhibitors for targeting cancer Stem cells
  1762. Non‐steady‐state hematopoiesis regulated by the C/EBP β transcription factor
  1763. Prmt5 is a regulator of muscle Stem cell expansion in adult mice
  1764. Autonomous extracellular matrix remodeling controls a progressive adaptation in muscle Stem cell regenerative capacity during development
  1765. Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery
  1766. Targeting the Stem cell niche with regenerative biomaterials
  1767. Concise review: asymmetric cell divisions in Stem cell biology
  1768. LECT2 drives haematopoietic Stem cell expansion and mobilization via regulating the macrophages and osteolineage cells
  1769. Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic Stem cells in aged C57BL/6 J mice
  1770. Jonathan A. Brassard, Natalie Fekete
  1771. Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age
  1772. Stem cell toxicology: a powerful tool to assess pollution effects on human health
  1773. Neuropeptide Y regulates the hematopoietic Stem cell microenvironment and prevents nerve injury in the bone marrow
  1774. Autophagy and Metabolism
  1775. Biology of healthy aging and longevity
  1776. Limbal Stem cell Transplantation for Soft Contact Lens Wear–Related Limbal Stem cell Deficiency
  1777. Genome surveillance in pluripotent Stem cells: Low apoptosis threshold and efficient antioxidant defense
  1778. Satellite cells in muscular dystrophy–lost in polarity
  1779. Genome instability of ageing Stem cells—induction and defence mechanisms
  1780. Stromal cells in phyllodes tumors of the breast are enriched for EZH2 and Stem cell marker expression
  1781. Chromatin remodeling factor BRM is essential for the maintenance of HSC quiescence
  1782. Molecular Mechanisms of Muscle Stem cell Aging
  1783. Effects of poor maternal nutrition during gestation on bone development and mesenchymal Stem cell activity in offspring
  1784. mTOR signaling promotes Stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration
  1785. Asymmetric apportioning of aged mitochondria between daughter cells is required for Stemness
  1786. Ageing induced vascular smooth muscle cell senescence in atherosclerosis
  1787. Anti-Aging Effect of Siraitia grosuenorii by Enhancement of Hematopoietic Stem cell Function
  1788. Microenvironmental regulation of hematopoietic Stem cells and its implications in leukemogenesis
  1789. The master switchers in the aging of cardiovascular syStem, reverse senescence by microRNA signatures; as highly conserved molecules
  1790. Deficiency in aryl hydrocarbon receptor (AHR) expression throughout aging alters gene expression profiles in murine long-term hematopoietic Stem cells
  1791. Inflammation as a driver of clonal evolution in myeloproliferative neoplasm
  1792. Stem cell and idiopathic pulmonary fibrosis: mechanisms and treatment
  1793. Stem cell guidance through the mechanistic target of rapamycin
  1794. Generation of Mouse Pluripotent Stem cell –Derived Proliferating Myeloid Cells as an Unlimited Source of Functional Antigen-Presenting Cells
  1795. Dynamics And Aging Of Hematopoietic Stem Cells
  1796. p38 mitogen-activated protein kinase inhibition enhances in vitro erythropoiesis of Fanconi anemia, complementation group A–deficient bone marrow cells
  1797. GRK6 regulates ROS response and maintains hematopoietic Stem cell self-renewal
  1798. Gene delivery for treating neurological disorders
  1799. Signaling pathways and modifiers in cardiac function in muscular dystrophy
  1800. A pre-clinical model of LGMD1D/DNAJB6 associated muscle disease: Expanding the role of HSP chaperones in skeletal muscle
  1801. Aging, clonality, and rejuvenation of hematopoietic Stem cells
  1802. Huajia Zhang, Sonia Rodriguez, 2 Lin Wang, 2 Soujuan Wang, 3 Henrique Serezani, 3 Reuben Kapur, 2
  1803. Epigenetic perturbations in aging Stem cells
  1804. Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo expansion of haematopoietic Stem cells
  1805. The hair follicle Stem cell niche: the bulge and its environment
  1806. CD8+ T cells drive autoimmune hematopoietic Stem cell dysfunction and bone marrow failure
  1807. Poly (ADP-Ribose) Polymerases in Aging–Friend or Foe?
  1808. The functional interplay between syStemic cancer and the hematopoietic Stem cell niche
  1809. High glutathione and glutathione peroxidase-2 levels mediate cell -type-specific DNA damage protection in human induced pluripotent Stem cells
  1810. Regulation of T cell differentiation and function by EZH2
  1811. Coenzyme Q10 inhibits the aging of mesenchymal Stem cells induced by D-galactose through Akt/mTOR signaling
  1812. Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic Stem and progenitor cells
  1813. Nanog down-regulates the Wnt signaling pathway via β-catenin phosphorylation during epidermal Stem cell proliferation and differentiation
  1814. Clonal hematopoiesis of indeterminate potential: a risk factor for hematologic neoplasms
  1815. DNA damage-induced HSPC malfunction depends on ROS accumulation downstream of IFN-1 signaling and bid mobilization
  1816. Runx1 downregulates Stem cell and megakaryocytic transcription programs that support niche interactions
  1817. Dystrophin expression in muscle Stem cells regulates their polarity and asymmetric division
  1818. An emerging interplay between altered human lipid metabolism, lipodystrophy and aging
  1819. Foxc1 reinforces quiescence in self-renewing hair follicle Stem cells
  1820. Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the In Vivo Regeneration of the Hematopoietic Stem cell Pool
  1821. Diet‐induced obesity in mice diminishes hematopoietic Stem and progenitor cells in the bone marrow
  1822. Oxidative stress in the aging process: fundamental aspects and new insights
  1823. Blue journal conference. Aging and susceptibility to lung disease
  1824. Analysis of Germline Stem cell Differentiation Following Loss of GLP-1 Notch Activity in Caenorhabditis elegans
  1825. The Role of Cathepsin K in Hematopoiesis
  1826. The Role of U2AF1 Mutations in the Pathogenesis of Myelodysplastic Syndromes
  1827. An in vivo evaluation of aneuploid hematopoietic Stem cell fitness
  1828. Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells
  1829. Epigenetic regulations of hematopoietic Stem cells ageing and the regulation of traditional Chinese medicine
  1830. Ageing of the Stem Cells: The Conjoined Twosome Growing Old: Stem cell and Its Niche
  1831. 281. Enforced Expression of a Mutant HMGA2 Gene Leads to Competitive Expansion and High Level Marking of Long-Term Hematopoietic Stem Cells in …
  1832. Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration
  1833. Pituitary Regeneration: It’ll Knock Your SOX Off!
  1834. Dyskeratosis congenita induced cirrhosis for liver transplantation-perioperative management
  1835. 3-Phosphoinositide-dependent kinase-1 (PDK1)-mediated signaling regulates hematopoietic Stem cell (HSC) quiesence by governing the oxidative response
  1836. Stem cell Transplantation for Degenerative Muscle Diseases
  1837. The potential roles of EZH2 in regenerative medicine
  1838. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer Stem-like cells
  1839. Invertebrates as model organisms for research on aging biology
  1840. Enhancer of zeste homolog 2 is widely expressed in T-cell neoplasms, is associated with high proliferation rate and correlates with MYC and pSTAT3 expression in a …
  1841. Is chronic obstructive pulmonary disease an accelerated aging disease?
  1842. Anti-aging strategies based on cellular reprogramming
  1843. P53 regulates disruption of neuronal development in the adult hippocampus after irradiation
  1844. Androgen therapy in Fanconi anemia: a retrospective analysis of 30 years in Germany
  1845. Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages
  1846. PRC 2 preserves intestinal progenitors and restricts secretory lineage commitment
  1847. Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses
  1848. Satellite cell heterogeneity in skeletal muscle homeostasis
  1849. Dangerous entrapment for NRF2
  1850. Regulation of Stem Cells in Their Niche
  1851. Ageing and the pathogenesis of osteoarthritis
  1852. Epigenetic Modulation: A Promising Avenue to Advance Hematopoietic Stem cell -Based Therapy for Severe Autoimmune Disorders
  1853. CDK7 and miR-210 co-regulate cell -cycle progression of neural progenitors in the developing neocortex
  1854. Association of TGFβ signaling with the maintenance of a quiescent Stem cell niche in human oral mucosa
  1855. Repression of the antioxidant NRF2 pathway in premature aging
  1856. Molecular regulation and rejuvenation of muscle Stem (satellite) cell aging
  1857. mTOR Signaling Promotes Stem cell Activation via Counterbalancing BMP-Mediated Suppression During Hair Regeneration
  1858. MERIT40 deficiency expands hematopoietic Stem cell pools by regulating thrombopoietin receptor signaling
  1859. Stem cells: a renaissance in human biology research
  1860. Redox theory of aging
  1861. E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis
  1862. Transplantation of endothelial cells to mitigate acute and chronic radiation injury to vital organs
  1863. Stem cells and aberrant signaling of molecular syStems in skin aging
  1864. Metabolic control of longevity
  1865. Glioblastoma: molecular pathways, Stem cells and therapeutic targets
  1866. Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
  1867. In vivo gene editing in dystrophic mouse muscle and muscle Stem cells
  1868. Clonal evolution of Stem cells in the gastrointestinal tract
  1869. Genomics of Lung Aging and Idiopathic Pulmonary Fibrosis
  1870. Mechanisms involved in the development of the chronic gastrointestinal syndrome in nonhuman primates after total-body irradiation with bone marrow shielding
  1871. EZH2 in normal hematopoiesis and hematological malignancies
  1872. Molecular pathways: targeting cancer Stem cells awakened by chemotherapy to abrogate tumor repopulation
  1873. Inhibition of mTOR sensitizes breast cancer Stem cells to radiation-induced repression of self-renewal through the regulation of MnSOD and Akt
  1874. Aging of Stem and progenitor cells: mechanisms, impact on therapeutic potential, and rejuvenation
  1875. Regenerative biology of tendon: mechanisms for renewal and repair
  1876. Molecular insights into the premature aging disease progeria
  1877. Hair follicle aging is driven by transepidermal elimination of Stem cells via COL17A1 proteolysis
  1878. The role of aging in idiopathic pulmonary fibrosis
  1879. Wnt activity and basal niche position sensitize intestinal Stem and progenitor cells to DNA damage
  1880. Stem cell Aging Research Literatures
  1881. Cardiomyocyte Regeneration in the mdx Mouse Model of Nonischemic Cardiomyopathy
  1882. The Stem cell Niche and Its Role in Self-Renewal, Aging, and Malignancy
  1883. Inflammatory signals in HSPC development and homeostasis: Too much of a good thing?
  1884. Altered gut microbiota composition in Rag1-deficient mice contributes to modulating homeostasis of hematopoietic Stem and progenitor cells
  1885. Heterogeneous Stem Cells in Skin Homeostatis and Wound Repair
  1886. CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic Stem/progenitor cells
  1887. Mesenchymal stromal cell -derived extracellular vesicles promote myeloid-biased multipotent hematopoietic progenitor expansion via toll-like receptor …
  1888. Epigenetic and Pten Regulation of Longevity Pathways Related to Idiopathic Pulmonary Fibrosis and Organismal Aging
  1889. Characterization of bone marrow-derived mesenchymal Stem cells in aging
  1890. Protective effect of ginsenoside Rg1 on hematopoietic Stem/progenitor cells through attenuating oxidative stress and the Wnt/β-catenin signaling pathway in a mouse …
  1891. Effective activity of cytokine induced killer cells against hepatocellular carcinoma including tumor-initiating cells
  1892. Are aberrant phase transitions a driver of cellular aging?
  1893. MUC5B and idiopathic pulmonary fibrosis
  1894. Aging of human haematopoietic Stem cells
  1895. Genome-wide DNA methylation changes during aging
  1896. Aging and uremia: Is there cellular and molecular crossover?
  1897. Paradoxical role of SOX2 in gastric cancer
  1898. Regulatory roles of miRNAs in aging
  1899. Early injury of the neonatal lung contributes to premature lung aging: a hypothesis
  1900. MicroRNA-Mediated Translational Control in Stem Cells: Self-Renewal and Therapeutic Implications
  1901. Epigenetic gene regulation and Stem cell function
  1902. The circadian clock in skin: implications for adult Stem cells, tissue regeneration, cancer, aging, and immunity
  1903. mTOR is necessary for proper satellite cell activity and skeletal muscle regeneration
  1904. Fbw7 and its counteracting forces in Stem cells and cancer: Oncoproteins in the balance
  1905. Understanding age-related diseases: report of the 2015 Ageing Summit
  1906. Loss of RUNX1 function results in enhanced granulocyte-colony-stimulating factor-mediated mobilization
  1907. The impact of leukemic microenvironment on normal hematopoiesis
  1908. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes
  1909. Gastrocnemius medialis muscle architecture and physiological cross sectional area in adult males with Duchenne muscular dystrophy
  1910. Postgraduate haematology
  1911. A comparative view of regenerative neurogenesis in vertebrates
  1912. Prospective study of ocular manifestations of pemphigus and bullous pemphigoid identifies a high prevalence of dry eye syndrome
  1913. Polycomb-like 2 (Mtf2/Pcl2) is required for epigenetic regulation of hematopoiesis
  1914. Correlation of smoking-associated DNA methylation changes in buccal cells with DNA methylation changes in epithelial cancer
  1915. The aging epigenome
  1916. The roles of Polycomb group proteins in hematopoietic Stem cells and hematological malignancies
  1917. Exome and whole genome sequencing in aging and longevity
  1918. Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts
  1919. mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model
  1920. Molecular mechanisms of biological aging in intervertebral discs
  1921. High-throughput screening identifies artesunate as selective inhibitor of cancer Stemness: involvement of mitochondrial metabolism
  1922. Self-renewal and high proliferative colony forming capacity of late-outgrowth endothelial progenitors is regulated by cyclin-dependent kinase inhibitors driven by notch …
  1923. The proliferation of amplifying neural progenitor cells is impaired in the aging brain and restored by the mTOR pathway activation
  1924. Rejuvenation on the Road to Pluripotency
  1925. The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?
  1926. Sox9-positive progenitor cells play a key role in renal tubule epithelial regeneration in mice
  1927. Role for the aryl hydrocarbon receptor and diverse ligands in oral squamous cell carcinoma migration and tumorigenesis
  1928. Gene Therapy and cell Fusion Enhances Stem cell Mediated Cardiac Repair
  1929. Renal Stem Cells, Tissue Regeneration, and Stem cell Therapies for Renal Diseases
  1930. Strategies to prevent “bad luck” in cancer
  1931. Evolutionarily conserved signaling pathways: acting in the shadows of acute myelogenous leukemia’s genetic diversity
  1932. cell autonomous and non-autonomous effects of senescent cells in the skin
  1933. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases
  1934. Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression
  1935. The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy
  1936. Human artificial chromosomes for Duchenne muscular dystrophy and beyond: challenges and hopes
  1937. Accelerated lung aging in COPD: a lung tissue gene expression signature
  1938. Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands
  1939. CCND1–CDK4–mediated cell cycle progression provides a competitive advantage for human hematopoietic Stem cells in vivo
  1940. Chromosome organisation during ageing and senescence
  1941. Impact of the circadian clock on the aging process
  1942. Proteostatic Mechanisms and Degree of Transcriptional Change with Age in Different Neural Stem cell Populations
  1943. Antisense strategies targeting DUX4 and DUX4c as therapeutic approaches for facioscapulohumeral muscular dystrophy (FSHD)
  1944. Ageing as an important risk factor for cancer
  1945. Increased red cell distribution width in Fanconi anemia: a novel marker of stress erythropoiesis
  1946. Emerging roles of frailty and inflammaging in risk assessment of age-related chronic diseases in older adults: the intersection between aging biology and …
  1947. Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis
  1948. Loss of miR-143 and miR-145 inhibits hematopoietic Stem cell self-renewal via dysregulated TGF-beta signaling
  1949. Pluripotent Stem cells and their dynamic niche
  1950. Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic Stem cells in transplantation and gene therapy
  1951. Anti-aging effect of transplanted amniotic membrane mesenchymal Stem cells in a premature aging model of Bmi-1 deficiency
  1952. Adipaging’: ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue
  1953. Deficient activity of the nuclease MRE11A induces T cell aging and promotes arthritogenic effector functions in patients with rheumatoid arthritis
  1954. Multi-drug resistance ABC transporter inhibition enhances murine ventral prostate Stem/progenitor cell differentiation
  1955. Isolation of THY1+ undifferentiated spermatogonia from mouse postnatal testes using magnetic-activated cell sorting (MACS)
  1956. The zebrafish as a gerontology model in nervous syStem aging, disease, and repair
  1957. Women Win Turning Older
  1958. Senescence is involved in the pathogenesis of chronic obstructive pulmonary disease through effects on telomeres and the anti‐aging molecule fibroblast growth …
  1959. Targeted Therapy in Myelodysplastic Syndromes
  1960. Distinct germline progenitor subsets defined through Tsc2–mTORC 1 signaling
  1961. Concise review: custodians of the transcriptome: how microRNAs guard Stemness in squamous epithelia
  1962. Aging of Mammalian Intestinal Stem Cells
  1963. RUNX1B expression is highly heterogeneous and distinguishes megakaryocytic and erythroid lineage fate in adult mouse hematopoiesis
  1964. Long-lasting WNT-TCF response blocking and epigenetic modifying activities of Withanolide F in human cancer cells
  1965. Do we need more drugs for chronic myeloid leukemia?
  1966. cell Competition: Roles and Importance as a Central Phenomenon
  1967. Autophagy regulates the cell cycle of murine HSPCs in a nutrient-dependent manner
  1968. Non-lethal ionizing radiation promotes aging-like phenotypic changes of human hematopoietic Stem and progenitor cells in humanized mice
  1969. Bone microenvironment signals in osteosarcoma development
  1970. Mouse models for core binding factor leukemia
  1971. Isolation of THY1+ Undifferentiated Spermatogonia from Mouse Postnatal Testes Using Magnetic-activated cell Sorting (MACS)
  1972. Epigenetic regulation of muscle Stem cell expansion
  1973. Pharmaceutical rejuvenation of age-associated decline in spatial memory
  1974. Activation of non-myogenic mesenchymal Stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice
  1975. Medullary thymic epithelial Stem cells: role in thymic epithelial cell maintenance and thymic involution
  1976. Epigenetic Responses to Diet in Aging
  1977. PTEN: multiple functions in human malignant tumors
  1978. Aging and lung disease. Clinical impact and cellular and molecular pathways
  1979. Neuropeptide Y induces hematopoietic Stem/progenitor cell mobilization by regulating matrix metalloproteinase-9 activity through Y1 receptor in osteoblasts
  1980. The role of hydrogen sulfide in aging and age-related pathologies
  1981. Concise review: quiescence in adult Stem cells: biological significance and relevance to tissue regeneration
  1982. Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs
  1983. Therapy of endocrine disease: improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing’s …
  1984. Impact of nutrition on the ageing process
  1985. Progerin expression disrupts critical adult Stem cell functions that mediate tissue repair primarily through a mechanism that permanently farnesylates lamin A
  1986. cell therapy strategies to combat immunosenescence
  1987. Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal Stem cells
  1988. Telomeres and Immunodeficiencies
  1989. Lin28 and let-7 in the metabolic physiology of aging
  1990. Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis
  1991. Metabolic restructuring and cell fate conversion
  1992. Low doses of oxygen ion irradiation cause acute damage to hematopoietic cells in mice
  1993. Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases
  1994. Aging Skin: A Window to the Body
  1995. Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal Stem cells
  1996. Characterization of mammary epithelial Stem/progenitor cells and their changes with aging in common marmosets
  1997. MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic Stem cells
  1998. Update on acute myeloid leukemia Stem cells: New discoveries and therapeutic opportunities
  1999. Role of Proteinase 3 in bone marrow hematopoiesis and neutrophil function
  2000. Skeletal muscle fibrosis in the mdx/utrn+/-mouse validates its suitability as a murine model of Duchenne muscular dystrophy
  2001. PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL
  2002. Histone H2B monoubiquitination: roles to play in human malignancy
  2003. The role of aging in Alzheimer’s disease
  2004. Dystrophin: The dead calm of a dogma
  2005. A summary of the biological basis of frailty
  2006. As we age: Does slippage of quality control in the immune syStem lead to collateral damage?
  2007. RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity
  2008. MINI-SYMPOSIUM 2: CELLULAR AND MOLECULAR MECHANISMS OF FIBROSIS
  2009. Inhibition of Wnt/β-catenin signaling suppresses bleomycin-induced pulmonary fibrosis by attenuating the expression of TGF-β1 and FGF-2
  2010. Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute
  2011. Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases
  2012. COUP-TFII regulates satellite cell function and muscular dystrophy
  2013. EZH2 is overexpressed in laryngeal squamous cell carcinoma and enhances the Stem-like properties of AMC-HN-8 cells
  2014. Enforced expression of Hoxa5 in haematopoietic Stem cells leads to aberrant erythropoiesis in vivo
  2015. The aryl hydrocarbon receptor relays metabolic signals to promote cellular regeneration
  2016. Toward RNA repair of Diamond Blackfan Anemia hematopoietic Stem cells
  2017. Effects of Developmental Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Long-term Self-renewal of Murine Hematopoietic …
  2018. Inflammatory markers change with age, but do not fall beyond reported normal ranges
  2019. Tumor Dormancy, Quiescence, and Senescence
  2020. Connecting the dots: from DNA damage and repair to aging
  2021. Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
  2022. Coaxing Stem cells for skeletal muscle repair
  2023. ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation
  2024. The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
  2025. GATA2 germline mutations impair GATA2 transcription, causing haploinsufficiency: functional analysis of the p. Arg396Gln mutation
  2026. Emerging non-canonical functions and regulation by p53: p53 and Stemness
  2027. Animal and human models to understand ageing
  2028. Label-retaining stromal cells in mouse endometrium awaken for expansion and repair after parturition
  2029. The African turquoise killifish: a model for exploring vertebrate aging and diseases in the fast lane
  2030. Telomere-regulating genes and the telomere interactome in familial cancers
  2031. Ontogenetic memory of the cell
  2032. Evolutionary ecology of aging: time to reconcile field and laboratory research
  2033. Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer
  2034. Acquired tissue-specific promoter bivalency is a basis for PRC2 necessity in adult cells
  2035. AMPK function in aging process
  2036. Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming
  2037. DNA damage-inducible transcript 4 is an innate surveillant of hair follicular stress in vitamin D receptor knockout mice and a regulator of wound re-epithelialization
  2038. A novel lymphoid progenitor cell population (LSKlow) is restricted by p18INK4c
  2039. Adipose-derived mesenchymal Stem cells and their reparative potential in ischemic heart disease
  2040. Increased levels of p21 (CIP1/WAF1) correlate with decreased chondrogenic differentiation potential in synovial membrane progenitor cells.
  2041. On the occasion of world kidney day 2016; work together to better protect the kidney
  2042. Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice
  2043. CD49f acts as an inflammation sensor to regulate differentiation, adhesion, and migration of human mesenchymal Stem cells
  2044. Frailty for surgeons: review of a national institute on aging conference on frailty for specialists
  2045. Mutations in AML: prognostic and therapeutic implications
  2046. PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic Stem and progenitor cells
  2047. A small molecule screen exposes mTOR signaling pathway involvement in radiation-induced apoptosis
  2048. Epigenetics of hematopoiesis and hematological malignancies
  2049. THE EFFECT OF BONE MARROW DERIVED Stem CELLS ON AGE CHANGES OF SUBMANDIBULAR SALIVARY GLANDS (HISTOLOGICAL AND …
  2050. The mechanobiology of aging
  2051. PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells
  2052. Receptor-interacting protein 140 overexpression promotes neuro-2a neuronal differentiation by ERK1/2 signaling
  2053. Identification of factors promoting ex vivo maintenance of mouse hematopoietic Stem cells by long-term single-cell quantification
  2054. Muscle satellite cells: exploring the basic biology to rule them
  2055. Current research in aging: a report from the 2015 Ageing Summit
  2056. Hierarchal autophagic divergence of hematopoietic syStem
  2057. Cancer Stem Cells: Perspectives Beyond Immunophenotypes and Markers
  2058. Satellite cells and skeletal muscle regeneration
  2059. Oxidative stress, microRNAs and cytosolic calcium homeostasis
  2060. Phosphatase and tensin homologue: novel regulation by developmental signaling
  2061. Pluripotent Stem cells for gene therapy of degenerative muscle diseases
  2062. Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle
  2063. The delayed effects of acute radiation syndrome: evidence of long-term functional changes in the clonogenic cells of the small intestine
  2064. Rheumatoid arthritis, immunosenescence and the hallmarks of aging
  2065. Pharmacologic inhibition of JAK-STAT signaling promotes hair growth
  2066. Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy
  2067. cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors
  2068. Replicating through telomeres: a means to an end
  2069. Elimination of the geomagnetic field stimulates the proliferation of mouse neural progenitor and Stem cells
  2070. Patient-Derived Induced Pluripotent Stem Cells Provide a Regenerative Medicine Platform for Duchenne Muscular Dystrophy Heart Failure
  2071. Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic
  2072. The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic Stem cells
  2073. Changes in regenerative capacity through lifespan
  2074. The initial establishment and epithelial morphogenesis of the esophagus: a new model of tracheal–esophageal separation and transition of simple columnar into …
  2075. cell ageing: a flourishing field for neurodegenerative diseases
  2076. Derivation of Engrafting Skeletal Muscle Precursors from Human Embryonic Stem Cells Using Serum-Free Methods
  2077. Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells
  2078. Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic Stem cells
  2079. Targeting cell cycle regulators in hematologic malignancies
  2080. Anemia, fatigue and aging
  2081. An Updated Review On Hutchinson-Gilford Progeria Syndrome
  2082. Premature aging in chronic kidney disease and chronic obstructive pulmonary disease: similarities and differences
  2083. How Wnt/β-Catenin, TGF-β/BMP signalling effect senescence via polycomb.
  2084. Evidence for the hallmarks of human aging in replicatively aging yeast
  2085. Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development
  2086. New trends in aryl hydrocarbon receptor biology
  2087. Loss of B cells in patients with heterozygous mutations in IKAROS
  2088. A comprehensive transcriptomic analysis of differentiating embryonic Stem cells in response to the overexpression of Mesogenin 1
  2089. Hutchinson–Gilford progeria syndrome
  2090. Blood Disorders in the Elderly
  2091. Halofuginone promotes satellite cell activation and survival in muscular dystrophies
  2092. What we know about the pathogenesis of idiopathic pulmonary fibrosis
  2093. A Novel Mechanism of Spermatogonia Death in Drosophila that Contributes to Tissue Homeostatis During Starvation.
  2094. C/EBPα in normal and malignant myelopoiesis
  2095. The impact of aging on cancer progression and treatment
  2096. Relative leukocyte telomere length, hematological parameters and anemia-data from the Berlin Aging Study II (BASE-II)
  2097. Age-related increase of EED expression in early hematopoietic progenitor cells is associated with global increase of the histone modification H3K27me3
  2098. Kindler syndrome, an orphan disease of cell /matrix adhesion in the skin–molecular genetics and therapeutic opportunities
  2099. Cancer and frailty in older adults: a nested case-control study of the Mexican Health and Aging Study
  2100. Regenerative Cells in the Ageing Lung
  2101. Current translational research and murine models for Duchenne muscular dystrophy
  2102. The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
  2103. Differential proteomic analysis of human placenta-derived mesenchymal Stem cells cultured on normal tissue culture surface and hyaluronan-coated surface
  2104. Radiation Sensitivity of Human CD34+ Cells Versus Peripheral Blood T Lymphocytes of Newborns and Adults: DNA Repair and Mutagenic Effects
  2105. The RUNX family: developmental regulators in cancer
  2106. DNA repair and aging: the impact of the p53 family
  2107. Hepatic angiosarcoma with dyskeratosis congenita
  2108. Primordial germ cells and germ line Stem cells
  2109. Host age is a syStemic regulator of gene expression impacting cancer progression
  2110. Dietary protein, metabolism, and aging
  2111. Epigenetics of idiopathic pulmonary fibrosis
  2112. mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
  2113. Signaling networks determining life span
  2114. Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine
  2115. Irreversible LSD1 inhibitors: application of tranylcypromine and its derivatives in cancer treatment
  2116. Nothobranchius furzeri: a model for aging research and more
  2117. Classification for longevity potential: the use of novel biomarkers
  2118. BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis
  2119. Id1 deficiency protects against tumor formation in ApcMin/+ mice but not in a mouse model of colitis-associated colon cancer
  2120. Atlas of cellular dynamics during zebrafish adult kidney regeneration
  2121. A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate
  2122. Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas
  2123. Telomerase and the Male Germline
  2124. The role of PI3K/AKT/mTOR inhibitors in the treatment of hematological malignancies
  2125. Genome-and cell -based strategies in therapy of muscular dystrophies
  2126. Influence of miR-155 on cell apoptosis in rats with ischemic stroke: role of the ras homolog enriched in brain (Rheb)/mTOR pathway
  2127. Epigenetics of aging
  2128. Posttranslational modifications of RUNX1 as potential anticancer targets
  2129. Practical Laboratory Medicine
  2130. Nutrients and ageing: what can we learn about ageing interactions from animal biology?
  2131. Adhesion receptors involved in HSC and early-B cell interactions with bone marrow microenvironment
  2132. Histone H2A deubiquitinase Mysm1 regulates p53 pathway activity in hematopoietic cells
  2133. Welcome to My Research! layer
  2134. Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention: do we really have an antiaging drug?
  2135. The impact of lung cancer on survival of idiopathic pulmonary fibrosis
  2136. Metabolic Control of Longevity
  2137. Identification of novel microRNA signatures linked to acquired aplastic anemia
  2138. Mesenchymal stromal cell -based therapies for lung disease
  2139. Ageing and the telomere connection: An intimate relationship with inflammation
  2140. Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy
  2141. Biomarkers of replicative senescence revisited
  2142. Exercise attenuates the major hallmarks of aging
  2143. Mapping the MYSM1 Transcriptional Network in Hematopoietic Stem and Progenitor Cells
  2144. Epigenetic modifications and accumulation of DNA double-strand breaks in oral lichen planus lesions presenting poor response to therapy
  2145. Megakaryocytic transcription factors in disease and leukemia
  2146. Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2
  2147. Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia
  2148. Mitophagy plays a central role in mitochondrial ageing
  2149. The Dnmt3L ADD domain controls cytosine methylation establishment during spermatogenesis
  2150. Combinations of kinase inhibitors protecting myoblasts against hypoxia
  2151. Oxidative stress-mediated skeletal muscle degeneration: molecules, mechanisms, and therapies
  2152. Molecules to medicine with mTOR: translating critical pathways into novel therapeutic strategies
  2153. MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis
  2154. Arantzazu Alfranca, Lucia Martinez-Cruzado, Juan Tornin, Ander Abarrategi, Teresa Amaral, Enrique de
  2155. Histogenesis of keratoacanthoma: histochemical and immunohistochemical study
  2156. Molecular basis of telomere dysfunction in human genetic diseases
  2157. Commentary: life course epidemiology embraces geroscience
  2158. Overexpression of PRAS40T246A in the proliferative compartment suppresses mtorc1 signaling, keratinocyte migration, and skin tumor development
  2159. Fate mapping and quantitation of hematopoiesis in vivo
  2160. LMNA Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper‐Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and …
  2161. Telomere dysfunction, chromosomal instability and cancer
  2162. EPIGENETIC SIGNIFICANCE OF CHROMATIN STRUCTURE IN CELLULAR AGEING
  2163. The role of osteocytes in age-related bone loss
  2164. Mechanisms of action of curcumin on aging: nutritional and pharmacological applications
  2165. Lack of Aryl Hydrocarbon Receptor Alters Gene Expression and Functional Capacity of Murine Hematopoietic Stem Cells
  2166. The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes
  2167. Age gene expression and coexpression progressive signatures in peripheral blood leukocytes
  2168. An update on the pathophysiology of osteoarthritis
  2169. H3K27 methylation: a focal point of epigenetic deregulation in cancer
  2170. Specific premature epigenetic aging of cartilage in osteoarthritis
  2171. SyStemic sclerosis-associated fibrosis: an accelerated aging phenotype?
  2172. A role for Galgt1 in skeletal muscle regeneration
  2173. A mitochondrial perspective of chronic obstructive pulmonary disease pathogenesis
  2174. Roles for the polycomb group protein BMI1 in lung adenocarcinoma progression and maintenance
  2175. Aging-related inflammation in osteoarthritis
  2176. Energetic interventions for healthspan and resiliency with aging
  2177. ROLE OF THE POLYCOMB GROUP PROTEINS IN THE ADULT INTESTINAL Stem CELLS HOMEOSTASIS
  2178. From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
  2179. The Role of Non-Myogenic Mesenchymal Stem Cells in Skeletal Muscle of Dystrophin/Utrophin Double Knockout Mice
  2180. Harnessing the Power of Stem Cells in Vaccine Against Mycobacterium tuberculosis
  2181. Epithelial Stem cells In Hutchinson-Gilford progeria syndrome
  2182. SyStemic DNA damage responses in aging and diseases
  2183. Impact of Leishmania donovani infection on early events in haematopoiesis
  2184. The regulation of satellite cell function and myogenesis by isoforms of C/EBPβ
  2185. Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice
  2186. Aging and multimorbidity: new tasks, priorities, and frontiers for integrated gerontological and clinical research
  2187. Biomarkers in Interstitial lung diseases
  2188. USP11 is a negative regulator to γH2AX ubiquitylation by RNF8/RNF168
  2189. Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
  2190. Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal Stem cells
  2191. An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium
  2192. ÔØ Å ÒÙ× Ö ÔØ
  2193. 7, 12-Dimethylbenz (a) anthracene-induced genotoxicity on bone marrow cells from mice phenotypically selected for low acute inflammatory response
  2194. The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis
  2195. Retinoid chemoprevention: who can benefit?
  2196. Why is aging conserved and what can we do about it?
  2197. Antioxidant potential of phycobiliproteins: Role in anti-aging research
  2198. Research & Reviews: Research Journal of Biology
  2199. MicroRNAs as potential targets for progressive pulmonary fibrosis
  2200. The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain
  2201. Nonspecific interstitial pneumonia: what is the optimal approach to management?
  2202. Telomeres in Liver Transplantation Allografts
  2203. Dystrophin induced cognitive impairment: mechanisms, models and therapeutic strategies
  2204. The Intrinsic Apoptotic Cascade in Hematopoiesis and Susceptibility to Therapy-Related Leukemia
  2205. Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF)
  2206. An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
  2207. Extended clinical and genetic spectrum associated with biallelic RTEL1 mutations
  2208. Poloxamer 188 attenuates cerebral hypoxia/ischemia injury in parallel with preventing mitochondrial membrane permeabilization and autophagic activation
  2209. Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation
  2210. Prevalence of Obstructive Sleep Apnoea in Patients with Idiopathic Pulmonary Fibrosis
  2211. Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development
  2212. Replicating through telomeres: a means to an end.
  2213. Characterizing the functional role of argonaute protein PIWIL4 in acute myeloid leukemia
  2214. Disturbing the histone code in leukemia: translocations and mutations affecting histone methyl transferases
  2215. The importance of detailed epigenomic profiling of different cell types within organs
  2216. HIV and aging
  2217. Drug discovery of therapies for duchenne muscular dystrophy
  2218. Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation
  2219. Connective tissue diseases, multimorbidity and the ageing lung
  2220. Disease drivers of aging
  2221. The Impact of Cancer Treatments on Aging
  2222. Role of sirtuins in maintenance of genomic stability: relevance to cancer and healthy aging
  2223. Ageing and inflammation–a central role for mitochondria in brain health and disease
  2224. Safety considerations for epigenetic mechanisms as drug targets: Are existing toxicology studies fit for purpose
  2225. Stop Aging Disease! ICAD 2014
  2226. Epigenetic modifiers in normal and malignant hematopoiesis
  2227. Does EBV alter the pathogenesis of malaria?
  2228. TeloPIN: a database of telomeric proteins interaction network in mammalian cells
  2229. Mitochondrial form, function and signalling in aging
  2230. M1 and M2 functional imprinting of primary microglia: role of P2X7 activation and miR-125b
  2231. Defects in homologous recombination repair behind the human diseases: FA and HBOC
  2232. Rheumatoid arthritis, immunosenescence and the hallmarks of aging
  2233. DNA damage: a main determinant of vascular aging
  2234. An aryl hydrocarbon receptor-mediated amplification loop that enforces cell migration in ER−/PR−/Her2− human breast cancer cells
  2235. The effects of aging on hematopoietic Stem cells
  2236. Biological and clinical significance of chronic herpes virus infection in patients undergoing treatment for myeloid malignancies
  2237. MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1
  2238. Pharmacological strategies to retard cardiovascular aging
  2239. Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling
  2240. Pharyngeal satellite cells undergo myogenesis under basal conditions and are required for pharyngeal muscle maintenance
  2241. Calorie restriction as an intervention in ageing
  2242. Molecular diagnosis and precission therapeutic approaches for telomere biology disorders
  2243. Studying the role of Sirtuin-1 gene in the maintenance of mouse intestinal epithelium
  2244. Bone marrow: A new way of modeling a classic organ
  2245. Idiopathic Pulmonary Fibrosis: Clinical Behavior, Pathogenic Mechanisms and Therapeutic Approach
  2246. Primitive Neural Stem Cells in the Mouse Brain
  2247. Epigenetics in lung fibrosis: from pathobiology to treatment perspective
  2248. Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression
  2249. Expression of CDK7, cyclin H, and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor–positive breast cancer
  2250. Nutrients, foods, dietary patterns and telomere length: Update of epidemiological studies and randomized trials
  2251. Unexpected off-targets and paradoxical pathway activation by kinase inhibitors
  2252. Supplementation with Lactobacillus plantarum WCFS1 prevents decline of mucus barrier in colon of accelerated aging Ercc1−/Δ7 mice
  2253. The protective role of liquiritin in high fructose-induced myocardial fibrosis via inhibiting NF-κB and MAPK signaling pathway
  2254. Telomere and telomerase stability in human diseases and cancer
  2255. Vitamin C, antioxidant status, and cardiovascular aging
  2256. The biology of aging: citizen scientists and their pets as a bridge between research on model organisms and human subjects
  2257. Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age‐related disorders
  2258. Somatic expression of unc-54 and vha-6 mRNAs declines but not pan-neuronal rgef-1 and unc-119 expression in aging Caenorhabditis elegans
  2259. Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 …
  2260. From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
  2261. Human aging in the post-GWAS era: further insights reveal potential regulatory variants
  2262. Sleep and respiratory sleep disorders in idiopathic pulmonary fibrosis
  2263. Telomere replication stress induced by POT1 inactivation accelerates tumorigenesis
  2264. Chondrosenescence: definition, hallmarks and potential role in the pathogenesis of osteoarthritis
  2265. The inhibitory mechanism of Cordyceps sinensis on cigarette smoke extract-induced senescence in human bronchial epithelial cells
  2266. THE TRUE EFFECTS OF EXERCISE ON HUMAN AGING.
  2267. Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia
  2268. Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation
  2269. SyStemic Factors Mediate Exercise-Induced Enhancement of Adult Hippocampal Neurogenesis
  2270. Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans
  2271. Photobiomodulatory effects of low intensity laser irradiation on isolated lung cancer Stem cells
  2272. Glutamine in sport and exercise
  2273. Meta-analysis of gene expression reversals in ageing brain
  2274. Effects of aging and short-term dietary restriction on neurogenesis and cellular senescence in the zebrafish (Danio Reio) brain
  2275. Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease
  2276. The potential of DNA modifications as biomarkers and therapeutic targets in oncology
  2277. The PI3K-mTOR Pathway
  2278. Unraveling variations in ribosome biogenesis activity in the mouse hematopoietic syStem at homeostasis in vivo
  2279. Osteoporosis and mechanisms of skeletal aging
  2280. 22.1 The AOP Concept in the Context of Risk Assessment Procedures
  2281. Structure and function of the telomeric CST complex
  2282. Aging of the immune syStem: focus on inflammation and vaccination
  2283. Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects
  2284. Inhibition of CDK7 bypasses spindle assembly checkpoint via premature cyclin B degradation during oocyte meiosis
  2285. The Neural Progenitor cell (NPC) Niche in the Adult Brain Provides a Target for Neurotoxicity: A Putative Adverse Outcome Pathway for ROS-Induced NPC …
  2286. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations
  2287. Porcine Models of Muscular Dystrophy
  2288. Suppression of STN1 enhances the cytotoxicity of chemotherapeutic agents in cancer cells by elevating DNA damage
  2289. Mitochondrial Priming and Anti-Apoptotic Dependencies in Aging and Diseased Bone Marrow
  2290. WIPI-mediated autophagy and longevity
  2291. Aging in COPD and idiopathic pulmonary fibrosis
  2292. Jacobs Journal of Gerontology
  2293. Biochemical and Functional Comparisons of mdx and Sgcg−/− Muscular Dystrophy Mouse Models
  2294. A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus
  2295. Mechanical overloading increases maximal force and reduces fragility in hind limb skeletal muscle from Mdx mouse
  2296. Lysosomal cathepsins and their regulation in aging and neurodegeneration
  2297. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
  2298. Histopathology and cryobiopsy
  2299. The Role of Environmental and Endogenous AHR Ligands in Estrogen Receptor, Progesterone Receptor, Human Epidermal Growth Factor Receptor 2-Negative (ER–/PR– …
  2300. Polyketide-based anti-aging therapeutic development via synthetic enzymology
  2301. High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice
  2302. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
  2303. Mitochondrial and ubiquitin proteasome syStem dysfunction in ageing and disease: two sides of the same coin?
  2304. Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis
  2305. Non-coding RNA repertoires in malignant pleural mesothelioma
  2306. P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy
  2307. Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation
  2308. In Silico Screening Based on Predictive Algorithms as a Design Tool for Exon Skipping Oligonucleotides in Duchenne Muscular Dystrophy
  2309. Aplastic anemia: from pathophysiology to diagnosis, management and treatment
  2310. Defective repair of uracil causes telomere defects in mouse hematopoietic cells
  2311. Targeted therapy for idiopathic pulmonary fibrosis: where to now?
  2312. Epigenetics of physiological and premature aging
  2313. Proteasome function is not impaired in healthy aging of the lung
  2314. Differentiation of Human Mesenchymal Stem Cells into Dopaminergic Neurons on Brain Electrode Materials
  2315. Regulation of the embryonic cell cycle during mammalian preimplantation development
  2316. Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy
  2317. Mechanisms of early hemato-endothelial development from human pluripotent Stem cells
  2318. CST complex and telomere maintenance
  2319. Interaction of p53 with prolyl isomerases: Healthy and unhealthy relationships
  2320. Internal Tandem Duplication of FLT3 Deregulates Proliferation and Differentiation and Confers
  2321. Computational biology in human aging: an omics data integration approach
  2322. Phosphoproteomic Characterization Of Glycogen Synthase Kinase-3
  2323. High-Throughput Analysis of Age-Dependent Protein Changes in Layer II/III of the Human Orbitofrontal Cortex
  2324. An oncogenic Ezh2 mutation cooperates with particular genetic alterations to induce tumors in mice and redistributes H3K27 trimethylation throughout the …
  2325. Human CST facilitates genome-wide RAD51 recruitment to GC-rich repetitive sequences in response to replication stress
  2326. Computational Biology in Human Aging
  2327. Autophagy in the hypothalamus: role of Neuropeptide Y and impact on Synaptic Plasticity
  2328. A phosphorylation–deubiquitination cascade regulates the BRCA2–RAD51 axis in homologous recombination
  2329. Maintenance of homeostasis in the aging hypothalamus: the central and peripheral roles of succinate
  2330. Development and Characterization of Tool Compounds Targeting the Runt Domain’s interaction With Cbfβ
  2331. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
  2332. Quantitative T2 combined with texture analysis of nuclear magnetic resonance images identify different degrees of muscle involvement in three mouse models …
  2333. Longevity of animals under reactive oxygen species stress and disease susceptibility due to global warming
  2334. Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential …
  2335. Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs
  2336. Nucleotide excision repair and transcriptional regulation: TFIIH and beyond
  2337. Small-molecule inhibition of functionally related transcriptional co-factors produces synergistic effects in T-cell acute lymphoblastic leukemia
  2338. Are invertebrates relevant models in ageing research? Focus on the effects of rapamycin on TOR
  2339. Dystrophinopathies
  2340. mTOR: a novel therapeutic target for diseases of multiple syStems
  2341. Autophagy and cellular senescence in lung diseases
  2342. The short-lived African turquoise killifish: an emerging experimental model for ageing
  2343. Epigenetic significance of chromatin organization during cellular aging and organismal lifespan
  2344. Revista de
  2345. The role of the aryl hydrocarbon receptor in megakaryocyte development
  2346. Biochemical pathways regulating mammary epithelial cell homeostasis and differentiation
  2347. Evaluation atraumatique de modèles murins de maladies musculaires génétiques
  2348. Nutrition in the Elderly: General Aspects
  2349. AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance
  2350. Modeling and analysis of acute leukemia using human hematopoietic Stem and progenitor cells
  2351. Modeling heart disease of patients with muscular dystrophy using induced pluripotent Stem cells
  2352. When anti-aging studies meet cancer chemoprevention: can anti-aging agent kill two birds with one blow?
  2353. The Hormone Nuclear Receptor DHR96 and its role in Ageing
  2354. Cross talk between fanconi anemia and unc5a signaling pathway
  2355. Ulm University Medicine| 2015: Research and Teaching
  2356. Congenital and Acquired Bone Marrow Failure
  2357. Mesenchymal-epidermal interactions in hair follicle cycling and regeneration
  2358. Inhibition of bone remodeling by anti-resorptive drugs displaces the plasma cell niche into the spleen
  2359. ICAM-1 in skeletal muscle disease and regeneration
  2360. Notable decrease in transcriptome conservation during mammalian aging
  2361. The Role of JAK2V617F-positive Endothelial Cells in Aberrant Haemostasis and Thrombosis
  2362. Therapeutic potential of retinoic acid-loaded nanoparticles for brain repair
  2363. Fibrosis: A Failure of Normal Repair and a Common Pathway to Organ Failure
  2364. A Mouse Model of Adynamic Bone Disease (ABD) and its Consequences on Bone Quality with Age
  2365. The protective role of protein L-isoaspartyl (D-aspartate) O-methyltransferase for maintenance of mitochondrial morphology in A549 cell
  2366. Characterizing miR-146a and miR-34a in B-cell lymphomagenesis
  2367. Renal Aging and Transplantation
  2368. Multitasking Roles for Poly (ADP-ribosyl) ation in Aging and Longevity
  2369. The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins
  2370. Bone Marrow Microenvironment regulation of BCL6 in Acute Lymphoblastic Leukemia
  2371. Evolution of the Telomere-Associated Protein POT1a in Arabidopsis thaliana Is Characterized by Positive Selection to Reinforce Protein–Protein Interaction
  2372. Mouse Models of Muscular Dystrophy and Type 2 Diabetes
  2373. Human Population Studies of Transcriptome-wide Expression in Age-related Traits
  2374. Structural Analysis of cell Signaling Complexes
  2375. The design & development of small molecule inhibitors targeting upregulated transcription factors in acute myeloid leukemia
  2376. Central regulation of food intake peptides during ageing in the teleost model Nothobranchius furzeri.
  2377. Age-related epigenetic changes at base excision repair genes and their modulation by dietary restriction in mice
  2378. Here be dragons: Science, technology and the future of humanity
  2379. Fibrocytes, y-Herpesvirus and Periostin Augment Bleomycin-induced Lung Fibrosis.
  2380. MicroRNA expression in regulatory T cells in chronic obstructive pulmonary disease
  2381. A Role for Protein Phosphatase 2A in the Proliferation-Quiescence Decision
  2382. Metal-induced oxidative stress in human fibroblasts: A role in cellular ageing
  2383. Effect of folate status and age on DNA methylation and gene expression
  2384. Identification of longevity and cancer resistance mechanisms in long-lived rodent species
  2385. Metabolic and Redox Effects of Intermittent Fasting
  2386. Investigating novel interaction partners of amyloid precursor protein: the mechanistic target of rapamycin and pikyve complex
  2387. Evaluation of WMircrotracker for assessing C. elegans stress responses
  2388. The role of macrophage migration inhibitory factor in osteoarthritis
  2389. Studies on the regulation of genome maintenance factors by non-covalent interaction with poly (ADP-ribose) with a focus on RECQL helicases
  2390. Connecting the functions of the proteasome and mitochondria in the lung
  2391. The effects of novel anti-inflammatory nutritional and pharmaceutical supplementation during resistance training on muscle and bone in older adults
  2392. An ERK-dependent feedback mechanism prevents hematopoietic Stem cell exhaustion
  2393. Adult Sox2+ Stem cell exhaustion in mice results in cellular senescence and premature aging
  2394. Autophagy in Stem cell aging
  2395. Increased Arf/p53 activity in Stem cells, aging and cancer
  2396. Regulation of Stem cell aging by metabolism and epigenetics
  2397. High‐fat diet–induced obesity promotes expansion of bone marrow adipose tissue and impairs skeletal Stem cell functions in mice
  2398. … Pathway Activation Induced By Combined Loss of Del (5q) MDS Genes, Tifab and Mir-146a, Accelerates Hematopoietic Stem cell exhaustion Driven By Chronic …
  2399. Targeting p53-dependent Stem cell loss for intestinal chemoprotection
  2400. Adult Sox2+ Stem cell exhaustion in mice results in cellular senescence and premature aging
  2401. Critical role of sox2 and p38mapkinase in Stem cell exhaustion , cognitive activity and organismal ageing
  2402. New mechanisms driving muscle Stem cell regenerative decline with aging
  2403. A quiescent Bcl11b high Stem cell population is required for maintenance of the mammary gland
  2404. Regeneration of injured tissue: Stem cell dynamics at interplay with mTORC1
  2405. Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic Stem cells
  2406. Id1 ablation protects hematopoietic Stem cells from stress-induced exhaustion and aging
  2407. Piwi is required to limit exhaustion of aging somatic Stem cells
  2408. Major Disruption of Bone Marrow Stromal cell Networks and Persistent Loss of Hematopoietic Stem cell Function upon Chronic Viral Infection
  2409. The metabolic programming of Stem cells
  2410. Automation in high throughput/content screening for cancer Stem cell drug discovery
  2411. Multiparameter Single cell Analysis to Identify Immune cell States That May Contribute to Successful Treatment Discontinuation in Patients with Chronic Myeloid …
  2412. Loss of Asrij/OCIAD1 in Mice Promotes Hematopoietic Stem and Progenitor cell Expansion Due to Increased CSN5-Mediated P53 Degradation
  2413. Molecular Determinants for Polycomb Group Protein YY1 Control of Hematopoietic Stem cell Quiescence
  2414. Reply to:“Lack of specificity of cytokeratin-15 loss in scarring alopecias”
  2415. Recent advances in understanding Werner syndrome
  2416. Manipulation of hematopoietic Stem cell fate by small molecule compounds
  2417. Cellular and epigenetic drivers of Stem cell ageing
  2418. Polycomb group protein YY1 is an essential regulator of hematopoietic Stem cell quiescence
  2419. Live-Imaging and Genetic Approaches to Study Resident Macrophage Progenitors
  2420. Proliferation drives aging-related functional decline in a subpopulation of the hematopoietic Stem cell compartment
  2421. Signaling pathways regulating hematopoietic Stem cell and progenitor aging
  2422. MYSM1 is essential for maintaining hematopoietic Stem cell (HSC) quiescence and survival
  2423. Recent advances in understanding hematopoiesis in Fanconi Anemia
  2424. Reactive oxygen species and mitochondrial homeostasis as regulators of Stem cell fate and function
  2425. Perspectives of aging study on Stem cell
  2426. Inhibition of BET bromodomain improves anemia in APCmin mice
  2427. Chronic inflammation in immune Aging: Role of Pattern Recognition Receptor Crosstalk with the Telomere Complex?
  2428. Altered redox balance in aging process: general mechanistic and clinical aspectseral mechanistic and clinical aspects
  2429. Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult …
  2430. Inflammation: a key regulator of hematopoietic Stem cell fate in health and disease
  2431. Setd2 regulates quiescence and differentiation of adult hematopoietic Stem cells by restricting RNA polymerase II elongation
  2432. Study on the Role of SIRT2 in Stem cell Aging and Chronic Inflammation
  2433. Aging hallmarks: the benefits of physical exercise
  2434. Long-term outcomes of ocular surface Stem cell allograft transplantation
  2435. Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
  2436. Chronic inflammation in immune aging: role of pattern recognition receptor crosstalk with the telomere complex?
  2437. Obstructive sleep apnea and hallmarks of aging
  2438. The biology of ageing and the omics revolution
  2439. mTORC1 activation during repeated regeneration impairs somatic Stem cell maintenance
  2440. Senescence in COPD and its comorbidities
  2441. Declined presentation loss of tRNA-methylation at cytosine 38 by Dnmt2 induces a hematopoietic Stem cell aging-like phenotype
  2442. Symmetric Stem cell division at the heart of adult neurogenesis
  2443. Aging and Chronic Respiratory Diseases: Novel Mechanisms
  2444. Division-independent differentiation mandates proliferative competition among Stem cells
  2445. The mammary Stem cell field wakes up to hibernating cells
  2446. The spectrum of fundamental basic science discoveries contributing to organismal aging
  2447. Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update
  2448. Preventing aging with Stem cell rejuvenation: Feasible or infeasible?
  2449. DIABETES ALTERS THE PROGENITOR PHENOTYPE FROM REGENERATIVE TO PRO-INFLAMMATORY: TRANSLATIONAL IMPLICATIONS FOR …
  2450. Scribble controls HSC self-renewal through polarity-dependent activation of the hippo signaling pathway
  2451. Stem cells hide from the sun
  2452. Stem cell Applications in Rejuvenation
  2453. Runx family genes in tissue Stem cell dynamics
  2454. Aging, metabolism and Stem cells: Spotlight on muscle Stem cells
  2455. Enhanced dentate neurogenesis after brain injury undermines long-term neurogenic potential and promotes seizure susceptibility
  2456. Mitochondria and FOXO3 in Stem cell homeostasis, a window into hematopoietic Stem cell fate determination
  2457. Unhealthy Stem cells: when health conditions upset Stem cell properties
  2458. Mammalian sterile 20 kinase 1 and 2 are important regulators of hematopoietic Stem cells in stress condition
  2459. Chronic kidney failure mineral bone disorder leads to a permanent loss of hematopoietic Stem cells through dysfunction of the Stem cell niche
  2460. Hand of FATe: lipid metabolism in hematopoietic Stem cells
  2461. Notch signaling in the regulation of hematopoietic Stem cell
  2462. Relationship between aging and hematopoietic cell transplantation
  2463. Autophagy controls mesenchymal Stem cell properties and senescence during bone aging
  2464. Aging With HIV and Oxidative Stress
  2465. Aged induced pluripotent Stem cell (iPSCs) as a new cellular model for studying premature aging
  2466. RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for Stem cell depletion
  2467. The mitochondrial respiratory chain is essential for haematopoietic Stem cell function
  2468. TRAF6 mediates basal activation of NF-κB necessary for hematopoietic Stem cell homeostasis
  2469. PDGFB-Expressing Mscs Improves Human Hematopoietic Stem cell Engraftment in Immunodeficient Mice
  2470. Profile of Helen M. Blau
  2471. Hematopoietic Stem Cells: Normal Versus Malignant
  2472. Aging of Human Adult Stem Cells
  2473. Aging of hematopoietic Stem cells
  2474. Meibocyte differentiation and renewal: insights into novel mechanisms of meibomian gland dysfunction (MGD)
  2475. Molecular Switch of AhR in Repression or Activation of Stem cell Signaling
  2476. Distinct molecular signature of murine fetal liver and adult hematopoietic Stem cells identify novel regulators of hematopoietic Stem cell function
  2477. Muscle Stem cells: a model syStem for adult Stem cell biology
  2478. The Basics of Biogerontology
  2479. Endogenous Stem cells in homeostasis and aging
  2480. Pharmacological regulation of oxidative stress in Stem cells
  2481. Induction of muscle Stem cell quiescence by the secreted niche factor Oncostatin M
  2482. Effect of aging on Stem cells
  2483. Unhealthy Stem Cells: When Health Conditions Upset Stem cell Properties
  2484. Blocking EZH2 methylation transferase activity by GSK126 decreases Stem cell -like myeloma cells
  2485. IFN-1 Bid crosstalk: foe or friend to Stem cells
  2486. miRNAs in Stem cell aging and age-related disease
  2487. A Quiescent Bcl11b High Epithelial cell is Required for Mammary Gland Regeneration
  2488. New genetic tools for the in vivo study of hematopoietic Stem cell function
  2489. Proteostatic and metabolic control of Stemness
  2490. Biology of premature ageing in survivors of cancer
  2491. Single Stem cell imaging and analysis reveals telomere length differences in diseased human and mouse skeletal muscles
  2492. Novel therapeutic strategies to target leukemic cells that hijack compartmentalized continuous hematopoietic Stem cell niches
  2493. Genomic instabilities, cellular senescence, and aging: in vitro, in vivo and aging-like human syndromes
  2494. Note: Page numbers followed by f and t indicate figures and tables respectivelyA
  2495. The Stem cell division theory of cancer
  2496. Rejuvenating strategies for Stem cell -based therapies in aging
  2497. Age is relative—impact of donor age on induced pluripotent Stem cell -derived cell functionality
  2498. Stem cell transcription factor FoxO controls microbiome resilience in Hydra
  2499. Tuning of the hematopoietic Stem cell compartment in its inflammatory environment
  2500. Localization of collagen type 5 in the papillary dermis and its role in maintaining Stem cell functions
  2501. Bioenergetics mechanisms regulating muscle Stem cell self-renewal commitment and function
  2502. Key age-imposed signaling changes that are responsible for the decline of Stem cell function
  2503. Chronic obstructive pulmonary disease and the hallmarks of aging
  2504. Comprehensive analysis of age-associated lncRNAs and function prediction in hepatocellular carcinoma
  2505. Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal Stem cell niche
  2506. Unleashing the guardian: the targetable BCR-ABL/HAUSP/PML/PTEN network in chronic myeloid leukemia
  2507. Circadian Rhythms and Their Impact on Aging
  2508. Paradoxical suppression of atherosclerosis in the absence of microRNA-146a
  2509. Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic Stem cells promotes proliferation but reduces competitive fitness
  2510. Muscle Stem cells exhibit distinct clonal dynamics in response to tissue repair and homeostatic aging
  2511. Cyclical expression of GDNF is required for spermatogonial Stem cell homeostasis
  2512. Oxidative stress in mesenchymal Stem cell senescence: regulation by coding and noncoding RNAs
  2513. Organoids with cancer Stem cell -like properties secrete exosomes and HSP90 in a 3D nanoenvironment
  2514. Mesenchymal Stem cells for frailty?
  2515. On the relationship between aging & cancer
  2516. General Introduction Aging of Hematopoietic Stem cells
  2517. Hydra, a model syStem for deciphering the mechanisms of aging and resistance to aging
  2518. Multi‐tasking epidermal Stem cells: Beyond epidermal maintenance
  2519. Role of muscle Stem cells in sarcopenia
  2520. Keeping the rhythm while changing the lyrics: circadian biology in aging
  2521. Comparison of nucleus pulposus Stem/progenitor cells isolated from degenerated intervertebral discs with umbilical cord derived mesenchymal Stem cells
  2522. Aspartic acid racemization on aging
  2523. Senolytic drugs in respiratory medicine: is it an appropriate therapeutic approach?
  2524. Role of MicroRNA-146a in Vascular Inflammation and Atherosclerosis
  2525. cell umbrella protects Stem cells from DNA damage
  2526. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated deregulation of myeloid and sebaceous gland Stem/progenitor cell homeostasis
  2527. Plasticity of the muscle Stem cell microenvironment
  2528. Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury
  2529. Epigenetic control of CXCL10: regulating the counterregulator in idiopathic pulmonary fibrosis
  2530. Molecular mechanisms to develop myeloid neoplasms by RUNX1 or MLL chimeras in human CD34+ cells
  2531. The mystery of longevity in Cilento: a mix of a good dose of genetic predisposition and a balanced diet based on the Mediterranean model
  2532. Identification of slow-cycling germline Stem cells and their regulation by PLZF
  2533. Transient CDK4/6 inhibition protects hematopoietic Stem cells from chemotherapy-induced exhaustion
  2534. Characterization of the ventricular-subventricular Stem cell niche during human brain development
  2535. A novel paradigm links mitochondrial dysfunction with muscle Stem cell impairment in sepsis
  2536. Note: Page numbers followed by f and t indicate figures and tables
  2537. Ectopic microRNAs used to preserve human mesenchymal Stem cell potency and epigenetics
  2538. Cxcr4-haploinsufficient bone marrow transplantation corrects leukopenia in an unconditioned WHIM syndrome model
  2539. A call to action in hematologic disorders: A report from the ASH scientific workshop on hematology and aging
  2540. CD41/CD61bright high ploidy megakaryocytes are critical for platelet production
  2541. Muscle Stem cell dysfunction impairs muscle regeneration in a mouse model of Down syndrome
  2542. Roles of the RUNX1 Enhancer in Normal Hematopoiesis and Leukemogenesis
  2543. Stem cells and DNA repair capacity: muse Stem cells are among the best performers
  2544. Role of epigenetic modulation in cancer Stem cell fate
  2545. mTOR as regulator of lifespan, aging, and cellular senescence: a mini-review
  2546. Pten is necessary for the quiescence and maintenance of adult muscle Stem cells
  2547. Ascorbic acid inhibits senescence in mesenchymal Stem cells through ROS and AKT/mTOR signaling
  2548. Anti-aging action of PPARs: Potential therapeutic targets
  2549. Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation
  2550. Hematopoietic Stem cells under pressure
  2551. Do hematopoietic Stem cells get old?
  2552. The Multi-pronged regulation of adult neurogenesis by forkhead box o family members
  2553. An essential role of CBL and CBL-B ubiquitin ligases in mammary Stem cell maintenance
  2554. Concise review: cell therapy for critical limb ischemia: an integrated review of preclinical and clinical studies
  2555. Checkpoint kinase 1 is essential for establishing fetal haematopoiesis and hematopoietic Stem and progenitor cell survival
  2556. Eco-aging: Stem cells and microbes are controlled by aging antagonist FoxO
  2557. Integrin‐FAK‐CDC42‐PP1A signaling gnaws at YAP/TAZ activity to control incisor Stem cells
  2558. CD133+ cells derived from skeletal muscles of Duchenne muscular dystrophy patients have a compromised myogenic and muscle regenerative capability
  2559. Stem Cells in Clinical Practice and Tissue Engineering
  2560. Senescence in health and disease
  2561. Methods and strategies for procurement, isolation, characterization, and assessment of senescence of human mesenchymal Stem cells from adipose tissue
  2562. Inhibition of methyltransferase Setd7 allows the in vitro expansion of myogenic Stem cells with improved therapeutic potential
  2563. ALTERED REDOX BALANCE IN AGING PROCESS: GENERAL MECHANISTIC AND CLINICAL ASPECTS
  2564. Stem cell Therapies in Peripheral Vascular Diseases—Current Status
  2565. The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
  2566. Proteasome activation enhances Stemness and lifespan of human mesenchymal Stem cells
  2567. A comprehensive analysis of differentially ex-pressed transcripts during hematopoietic Stem cell aging in the mouse
  2568. Wnt/β-catenin signaling promotes aging-associated hair graying in mice
  2569. ASXL1 AND EZH2
  2570. Nuclear pore complexes in DNA repair and telomere maintenance
  2571. PTEN mediates activation of core clock protein BMAL1 and accumulation of epidermal Stem cells
  2572. The histone variant macroH2A confers functional robustness to the intestinal Stem cell compartment
  2573. Mechanisms of lung aging
  2574. Lack of specificity of cytokeratin-15 loss in scarring alopecias
  2575. Wnt signalling in intestinal Stem cells: lessons from mice and flies
  2576. mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level
  2577. Dual role of the anaphase promoting complex/cyclosome in regulating Stemness and differentiation in human primary keratinocytes
  2578. Short telomeres induce p53 and autophagy and modulate age-associated changes in cardiac progenitor cell fate
  2579. Defining adult Stem cells by function, not by phenotype
  2580. mTOR signaling plays a critical role in the defects observed in muscle‐derived Stem/progenitor cells isolated from a murine model of accelerated aging
  2581. Analysis of senescence-related differentiation potentials and gene expression profiles in human dental pulp Stem cells
  2582. ADVANCE ARTICLE
  2583. DNMT3A in Leukemia
  2584. Telomeres in health and disease
  2585. Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
  2586. Investigating the role of the CCT chaperonin in Stem cell identity and aging
  2587. Stem cells seen through the FOXO lens: an evolving paradigm
  2588. Investigating the regenerative effects of adipose-derived mesenchymal Stem cell conditioned media on sarcopenic and progeric skeletal muscle
  2589. A storm in the niche: Iron, oxidative stress and haemopoiesis
  2590. Methylation maintains HSC division fate
  2591. Regeneration of the aging lung: a mini-review
  2592. Heterogeneity of GATA2-related myeloid neoplasms
  2593. A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models
  2594. Rapamycin prolongs the survival of corneal epithelial cells in culture
  2595. Stem cells, cancer, and MUSASHI in blood and guts
  2596. FOXO transcriptional factors and long-term living
  2597. Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia
  2598. Rapamycin rescues BMP mediated midline craniosynostosis phenotype through reduction of mTOR signaling in a mouse model
  2599. OCIAD1 controls electron transport chain complex I activity to regulate energy metabolism in human pluripotent Stem cells
  2600. The potential of iPSCs for the treatment of premature aging disorders
  2601. Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia
  2602. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing …
  2603. The critical role of inflammation in the pathogenesis and progression of myeloid malignancies
  2604. At the crossroads between neurodegeneration and cancer: a review of overlapping biology and its implications
  2605. Satellite cell -mediated breast muscle regeneration decreases with broiler size
  2606. mTOR signaling in Stem and progenitor cells
  2607. Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency
  2608. Bone marrow mesenchymal Stem cells: aging features and relevant treatments
  2609. Mechanisms of hematopoietic Stem cell ageing and targets for hematopoietic tumour prevention
  2610. Frailty and anesthesia
  2611. Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery
  2612. Myelopoiesis in the context of innate immunity
  2613. Hematopoietic Stem cell maintenance in steady-state and inflammation
  2614. Advanced glycation and aging
  2615. The secretome of MUSE cells contains factors that may play a role in regulation of Stemness, apoptosis and immunomodulation
  2616. Maintenance of redox homeostasis by hypoxia-inducible factors
  2617. Therapeutic potential, challenges and future perspective of cancer Stem cells in translational oncology: a critical review
  2618. cell Reprogramming: Mirage or Reality
  2619. Activation of neural Stem cells from quiescence drives reactive hippocampal neurogenesis after alcohol dependence
  2620. The syStem capacity view of aging and longevity
  2621. Memory beyond immunity
  2622. Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis
  2623. Isolation and prolonged expansion of oral mesenchymal Stem cells under clinical-grade, GMP-compliant conditions differentially affects “Stemness” properties
  2624. Towards a biological geriatric assessment
  2625. Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells
  2626. Conditional deletion of Ahr alters gene expression profiles in hematopoietic Stem cells
  2627. The biology of ageing
  2628. Therapies Targeting Leukemic Stem Cells
  2629. Malaria-induced remodelling of the bone marrow microenvironment mediates loss of haematopoietic Stem cell function
  2630. Proteolytic Networks at the Crossroads of Cancer cell Life and Death: Cancer Stem cell Deciding cell Fate
  2631. Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid leukemia (CML)
  2632. Modifying progression of aging and reducing the risk of neurodegenerative diseases by probiotics and synbiotics
  2633. Children living with progeria
  2634. Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies
  2635. Stem Cells and Tissue Regeneration
  2636. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice
  2637. Clonal hematopoiesis in aging
  2638. Total body irradiation tremendously impair the proliferation, differentiation and chromosomal integrity of bone marrow-derived mesenchymal stromal Stem cells
  2639. Bone marrow failure
  2640. Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in-mouse line
  2641. Reflections on aging and wisdom
  2642. Oxidative Stress in Mesenchymal Stem cell Senescence: Regulation by Coding and Noncoding RNAs. Antioxidants and Redox Signaling, 29 (9), 864-879 …
  2643. 9 Aging Epigenetics
  2644. Cellular and molecular mechanisms of sarcopenia: the S100B perspective
  2645. Niche Regulation of Muscle Stem cell Quiescence by Classical Cadherins
  2646. From TCDD-mediated toxicity to searches of physiologic AHR functions
  2647. Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin
  2648. RNA editing-dependent epitranscriptome diversity in cancer Stem cells
  2649. Dynamics of epigenome and 3D genome in hematopoietic Stem cell development
  2650. Meis1 is critical to the maintenance of human acute myeloid leukemia cells independent of MLL rearrangements
  2651. Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis
  2652. Human iPSC models to study orphan diseases: muscular dystrophies
  2653. Clearance of senescent cells: an immunotherapeutic approach
  2654. Notch and aryl hydrocarbon receptor signaling impact definitive hematopoiesis from human pluripotent Stem cells
  2655. Persistent inflammation, immunosuppression and catabolism after severe injury or infection
  2656. Research progress of intervertebral disc endogenous Stem cells for intervertebral disc regeneration
  2657. Impact of oxidative stress on telomere biology
  2658. Stem cell -based Modalities: From Basic Biology to Integration and Regeneration
  2659. Stem Cells as a Therapeutic Modality in Muscular Dystrophy
  2660. Assessment of TREC, KREC and telomere length in long-term survivors after allogeneic HSCT: the role of GvHD and graft source and evidence for telomere …
  2661. Pulmonary Disease in the Aging Patient
  2662. Notch/Wnt Cross-Signalling Regulates Stemness Of Dental Pulp Stem Cells Through Expression Of Neural Crest And Core Pluripotency Factors
  2663. Characterizing the cellular diversity and molecular signatures within the hair follicle dermal Stem cell lineage
  2664. Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7
  2665. Skeletal muscle metabolism: from tissue to Stem cell
  2666. Nucleosome remodelling, DNA repair and transcriptional regulation build negative feedback loops in cancer and cellular ageing
  2667. Evaluating intrinsic and non-intrinsic cancer risk factors
  2668. Mesenchymal Stem cells for the treatment of idiopathic pulmonary fibrosis
  2669. The role of matrix metalloproteinases in aging: Tissue remodeling and beyond
  2670. Commentary:” Promoting Myelin Repair through In vivo Neuroblast Reprogramming”
  2671. What’s in a name? That which we call IPF, by any other name would act the same
  2672. Proceedings: regenerative medicine for lung diseases: a CIRM workshop report
  2673. Mitochondria and Stem cell function: from somatic cells to iPSC-based disease modeling
  2674. Changing mutational and adaptive landscapes and the genesis of cancer
  2675. Secretome analysis of in vitro aged human mesenchymal Stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis
  2676. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects
  2677. Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
  2678. Wnt signaling in adult epithelial Stem cells and cancer
  2679. Rehmannia glutinosa exhibits anti‐aging effect through maintaining the quiescence and decreasing the senescence of hematopoietic Stem cells
  2680. Stabilization Of Disease Progression In A Case Of Duchenne Muscular Dystrophy With Cellular Transplantation
  2681. Mechanisms of vascular aging
  2682. Chronic infection stunts macrophage heterogeneity and disrupts immune-mediated myogenesis
  2683. Critical Assessment of the mdx Mouse with Ex Vivo Eccentric Contraction of the Diaphragm Muscle
  2684. MicroRNAs-103/107 regulate autophagy in the epidermis
  2685. Mouse models to disentangle the hallmarks of human aging
  2686. Tissue engineering and regenerative medicine: a translational research for antiaging strategy
  2687. RUNX transcription factors at the interface of Stem cells and cancer
  2688. Cancer-associated PIK3CA mutations in overgrowth disorders
  2689. Increased frequency of bronchiolar histotypes in lung carcinomas associated with idiopathic pulmonary fibrosis
  2690. Molecular and physiological manifestations and measurement of aging in humans
  2691. Aging: somatic mutations, epigenetic drift and gene dosage imbalance
  2692. Cross-organelle communication at the core of longevity
  2693. Development and characterization of a bone marrow Stem cell niche model
  2694. mTORC1 activates PASK-Wdr5 signaling to epigenetically connect the nutrient status with myogenesis
  2695. Why we age–a new evolutionary view
  2696. Regenerative medicine: induced pluripotent Stem cells and their benefits on accelerated bone tissue reconstruction using scaffolds
  2697. Aging and the immune syStem: An overview
  2698. Impaired mRNA expression of the migration related chemokine receptor CXCR4 in mesenchymal Stem cells of COPD patients
  2699. Modelling age-associated diseases using transgenic progerin expression
  2700. UHRF1 licensed self-renewal of active adult neural Stem cells
  2701. Age-related changes in nucleus pulposus mesenchymal Stem cells: an in vitro study in rats
  2702. Making gene editing a therapeutic reality
  2703. Aging and autophagy in hematopoietic Stem cells
  2704. The guardian of the genome revisited: p53 downregulates genes required for telomere maintenance, DNA repair, and centromere structure
  2705. DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation
  2706. Functional relevance of miRNAs in premature ageing
  2707. Unveiling epigenetic regulation in cancer, aging, and rejuvenation with in vivo reprogramming technology
  2708. Visualizing hematopoiesis as a stochastic process
  2709. Senescence and aging: Causes, consequences, and therapeutic avenues
  2710. Modulation of myelopoiesis progenitors is an integral component of trained immunity
  2711. and Vijayalakshmi Santhakumar
  2712. Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis
  2713. Microenvironment-cell nucleus relationship in the context of oxidative stress
  2714. Functional relevance of miRNAs in premature ageing
  2715. Apelin/APJ syStem: a novel promising target for anti-aging intervention
  2716. Introduction to Cardiovascular Aging Compendium: “Aging as the Quintessential Complex Phenotype”
  2717. Blood to Blood: A New Therapeutic Opportunity for Age-Related Diseases
  2718. Hematopoietic Stem/progenitor cell senescence is associated with altered expression profiles of cellular memory-involved gene
  2719. Novel strategies for anti-aging drug discovery
  2720. Elisia D. Tichy, David K. Sidibe, Matthew T. Tierney, 2 Michael J. Stec, 2 Maryam Sharifi-Sanjani
  2721. The role of decidual mesenchymal Stem/stromal cells and their secreted extracellular vesicles in ageing of the human placenta
  2722. Proteostatic and metabolic control of Stemness
  2723. PP242 counteracts glioblastoma cell proliferation, migration, invasiveness and Stemness properties by inhibiting mTORC2/AKT
  2724. Inhibition of Bcl-2/xl with ABT-263 selectively kills senescent type II pneumocytes and reverses persistent pulmonary fibrosis induced by ionizing radiation in mice
  2725. Aging and proteins: what does proteostasis have to do with age?
  2726. Next-generation sequencing and quantitative proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in …
  2727. Epigenetic regulation of skin cells in natural aging and premature aging diseases
  2728. Human aging and cancer: role of miRNA in tumor microenvironment
  2729. The Satellite cell Niche in Skeletal Muscle
  2730. SOX2 haploinsufficiency promotes impaired vision at advanced age
  2731. Circulating markers of ageing and allostatic load: a slow train coming
  2732. Cytomegalovirus retinitis as a presenting feature of multisyStem disorder: Dyskeratosis congenita
  2733. Introductory Chapter: Aging is a Preventable Disorder
  2734. Mammalian skeletal muscle fibres promote non-muscle Stem cells and non-Stem cells to adopt myogenic characteristics
  2735. VU Research Portal
  2736. The Responsibility of Immortality: Welcome to the New Transhumanism
  2737. Targeting glioma Stem cells through combined BMI1 and EZH2 inhibition
  2738. The aging lung: tissue telomere shortening in health and disease
  2739. The role of mTOR-mediated signals during haemopoiesis and lineage commitment
  2740. Satellite cells maintain regenerative capacity but fail to repair disease-associated muscle damage in mice with Pompe disease
  2741. Comorbidities, age, and other patient-related predictors of allogeneic hematopoietic cell transplantation outcomes
  2742. Time and the metrics of aging
  2743. Metabolic Regulation of Muscle Stem cell Histone Acetylation Landscape During Regeneration
  2744. Osthole delays Tert-butyl hydroperoxide-induced premature senescence in neural Stem cells
  2745. 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
  2746. MicroRNA profiling in cartilage ageing
  2747. Bone microRNAs and ageing
  2748. Why and how are we living longer?
  2749. Changing direction: from therapeutic telomerase inhibition to activation?
  2750. A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle Stem cells
  2751. Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway
  2752. Aging, inflammation and the environment
  2753. The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9
  2754. Loss of Stemness, EMT, and supernumerary tooth formation in Cebpb−/− Runx2+/− murine incisors
  2755. Extracellular vesicles, ageing, and therapeutic interventions
  2756. Agent-based model illustrates the role of the microenvironment in regeneration in healthy and mdx skeletal muscle
  2757. Communication and the Normal Aging Process
  2758. Secrets from immortal worms: what can we learn about biological ageing from the planarian model syStem?
  2759. Asthma in the elderly and late‐onset adult asthma
  2760. New phytochemicals as potential human anti-aging compounds: Reality, promise, and challenges
  2761. Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via …
  2762. Impact of the circadian clock on UV‐induced DNA damage response and photocarcinogenesis
  2763. RUNX1 suppresses breast cancer Stemness and tumor growth
  2764. Regulation of embryonic haematopoietic multipotency by EZH1
  2765. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
  2766. Cohesin in haematopoiesis and leukaemia
  2767. Candidate Interventions for Lifespan Studies
  2768. The prognostic value and potential drug target of phosphatase and tensin homolog in breast cancer patients: a meta-analysis
  2769. Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)
  2770. Wnt signaling in epithelial Stem cells and cancer
  2771. Current methods for skeletal muscle tissue repair and regeneration
  2772. Inflammatory memory sensitizes skin epithelial Stem cells to tissue damage
  2773. Satellite cells delivered in their niche efficiently generate functional myotubes in three-dimensional cell culture
  2774. Spermidine in health and disease
  2775. Sarcopenia: causes and treatments
  2776. Mesenchymal Stem cells secretory responses: senescence messaging secretome and immunomodulation perspective
  2777. Identification of Stem cells in the epithelium of the stomach corpus and antrum of mice
  2778. Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia
  2779. Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side
  2780. Human iPSC Models to Study Orphan Diseases: Muscular Dystrophies
  2781. Heart-breaking telomeres
  2782. Tumor-derived cytokines impair myogenesis and alter the skeletal muscle immune microenvironment
  2783. “Known unknowns”: Current questions in muscle satellite cell biology
  2784. Lung diseases of the elderly: cellular mechanisms
  2785. Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
  2786. Sarcopenia and aging
  2787. NAD+ in aging: molecular mechanisms and translational implications
  2788. Pre-transplantation blockade of TNF-α-mediated oxygen species accumulation protects hematopoietic Stem cells
  2789. I. Revue 1: Role of EZH2 in normal hematopoiesis and hematologic malignancies
  2790. Trauma and transfusion in the geriatric patient
  2791. cell -extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
  2792. The aging mitochondria
  2793. Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a
  2794. Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal Stem cells from differently aged donors
  2795. Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
  2796. ESRD-associated immune phenotype depends on dialysis modality and iron status: clinical implications
  2797. Physical exercise rescues defective neural Stem cells and neurogenesis in the adult subventricular zone of Btg1 knockout mice
  2798. Polycomb repressive complexes in hematological malignancies
  2799. Nfix Promotes Survival of Immature Hematopoietic Cells via Regulation of c-Mpl
  2800. Concise review: getting to the core of inherited bone marrow failures
  2801. Substrate topography modulates cell aging on a progeria cell model
  2802. Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer
  2803. The H3K4 methyltransferase Setd1b is essential for hematopoietic Stem and progenitor cell homeostasis in mice
  2804. High-dimensional phenotyping identifies age-emergent cells in human mammary epithelia
  2805. Investigating The Role Of Signaling Pathways In Adult Stem Cells Governed By Population Asymmetry
  2806. Type I IFNs drive hematopoietic Stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like …
  2807. Nucleolar expansion and elevated protein translation in premature aging
  2808. Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging
  2809. An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical …
  2810. Aging in the cardiovascular syStem: lessons from Hutchinson-Gilford progeria syndrome
  2811. Epithelial to mesenchymal transition-related proteins ZEB1, β-catenin, and β-tubulin-III in idiopathic pulmonary fibrosis
  2812. Humanizing the mdx mouse model of DMD: the long and the short of it
  2813. Long-term selection of chickens for body weight alters muscle satellite cell behaviors
  2814. Licence to kill senescent cells in idiopathic pulmonary fibrosis?
  2815. Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis
  2816. Radical life extension, cybernetic immortality, and techno‐salvation. Really?
  2817. Aging in Rothmund-Thomson syndrome and related RECQL4 genetic disorders
  2818. Programmed cell senescence in skeleton during late puberty
  2819. Sarcopenia, aging and prospective interventional strategies
  2820. Therapeutic interventions for aging: the case of cellular senescence
  2821. Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition
  2822. PTEN is fundamental for elimination of leukemia Stem cells mediated by GSK126 targeting EZH2 in chronic myelogenous leukemia
  2823. Potential mechanisms of age acceleration caused by estrogen deprivation: do endocrine therapies carry the same risks?
  2824. The association between obstructive sleep apnea and shortened telomere length: a syStematic review and meta-analysis
  2825. Mechanisms of cancer resistance in long-lived mammals
  2826. Constitutively active ABL family kinases, TEL/ABL and TEL/ARG, harbor distinct leukemogenic activities in vivo
  2827. Management of chronic lymphocytic leukemia (CLL) in the elderly: a position paper from an international Society of Geriatric Oncology (SIOG) Task Force
  2828. Basic characteristics of muse cells
  2829. SIRT1 regulates macrophage self‐renewal
  2830. Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations
  2831. Assessment of the anti-aging klotho protein in patients with COPD undergoing pulmonary rehabilitation
  2832. Emerging roles for sphingolipids in cellular aging
  2833. The Hippo pathway in normal development and cancer
  2834. Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent Stem cells
  2835. Targeting the Cellular Redox Environment: A Novel Approach for the Treatment of Hematopoietic Neoplasms
  2836. Quiescent Oct4+ Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein+ NSCs in the Adult Mouse Brain
  2837. Biomedical Research in Aging
  2838. Novel role of the SIRT4-OPA1 axis in mitochondrial quality control
  2839. Invertebrates as model organisms for research on aging biology
  2840. The intersection of aging biology and the pathobiology of lung diseases: a joint NHLBI/NIA workshop
  2841. Translational geroscience: A new paradigm for 21st century medicine
  2842. Genetic and tissue engineering approaches to modeling the mechanics of human heart failure for drug discovery
  2843. SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
  2844. Aging metabolism: intervention strategies
  2845. Modeling neuropsychiatric and neurodegenerative diseases with induced pluripotent Stem cells
  2846. Hair regeneration by small molecules that activate autophagy
  2847. Starvation signals in yeast are integrated to coordinate metabolic reprogramming and stress response to ensure longevity
  2848. Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis
  2849. Aging and anti-aging: a combo-endocrinology overview
  2850. Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
  2851. Chiara Zagni, Luciana O. Almeida, Tarek Balan, 3 Marco T. Martins, Luciana K. Rosselli-Murai
  2852. Pancytopenia: A Challenging Problem for Treating Physician
  2853. Interleukin-7 and immunosenescence
  2854. Role of miR-200c in myogenic differentiation impairment via p66Shc: implication in skeletal muscle regeneration of dystrophic mdx mice
  2855. DNA methylation-based age prediction from various tissues and body fluids
  2856. Foxp1 is indispensable for ductal morphogenesis and controls the exit of mammary Stem cells from quiescence
  2857. Elixir of life: thwarting aging with regenerative reprogramming
  2858. Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma
  2859. Immobilised growth factors for scalable cell therapy manufacturing platforms
  2860. Targeting aging for disease modification in osteoarthritis
  2861. Cellular senescence: a view throughout organismal life
  2862. Flagellin-Mediated Irradiation Protection in Mice
  2863. From lymphopoiesis to plasma cells differentiation, the age-related modifications of B cell compartment are influenced by “inflamm-ageing”
  2864. Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy
  2865. Epithelial autophagy and longevity of Hydra oligactis, a new model for aging research
  2866. The role of epigenetics in renal ageing
  2867. Physiology of ageing of the musculoskeletal syStem
  2868. EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms
  2869. Splicing regulatory factors, ageing and age-related disease
  2870. Decreased telomere length in children with cartilage-hair hypoplasia
  2871. Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response
  2872. Emerging Connections: Synaptic Autophagy in Brain Aging and Disease
  2873. Attenuation of PKC δ enhances metabolic activity and promotes expansion of blood progenitors
  2874. Hair growth stimulation by a natural remedy: Animal studies
  2875. RUNX1 mutations in inherited and sporadic leukemia
  2876. Gene expression signature of the ageing lung: breathing new life into COPD
  2877. A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells
  2878. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis
  2879. Mitochondrial quality control mechanisms as molecular targets in cardiac ageing
  2880. Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis
  2881. Molecular regulation of hair follicle Stem and progenitor cell homeostasis
  2882. MicroRNA-146a induces lineage-negative bone marrow cell apoptosis and senescence by targeting polo-like kinase 2 expression
  2883. DAF-16/FOXO transcription factor in aging and longevity
  2884. Skeletal muscle regenerative potential of human MuStem cells following transplantation into injured mice muscle
  2885. The molecular intersection between senescence and major depression in the elderly
  2886. Collagenase impacts the quantity and quality of native mesenchymal Stem/stromal cells derived during processing of umbilical cord tissue
  2887. Current advances and limitations in modeling ALS/FTD in a dish using induced pluripotent Stem cells
  2888. Relevance of the p53–MDM2 axis to aging
  2889. MMR deficiency does not sensitize or compromise the function of hematopoietic Stem cells to low and high LET radiation
  2890. Sox2 and Meis1 in tooth development and murine incisor renewal
  2891. Heme oxygenase-1 influences satellite cells and progression of Duchenne muscular dystrophy in mice
  2892. Horizons in the evolution of aging
  2893. Recent advances in lung regeneration
  2894. A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics
  2895. The aging population with HIV infection
  2896. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
  2897. Oral health in geroscience: animal models and the aging oral cavity
  2898. Epigenetic modifications in cardiovascular aging and diseases
  2899. How might transbronchial cryobiopsy improve diagnosis and treatment of diffuse parenchymal lung disease patients?
  2900. Targeting senescence to delay progression of multiple sclerosis
  2901. Rejuvenation of cardiac tissue developed from reprogrammed aged somatic cells
  2902. Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle
  2903. Oncological challenges for an ageing population living with HIV
  2904. Adaptive NK cells can persist in patients with GATA2 mutation depleted of Stem and progenitor cells
  2905. Making gene editing a therapeutic reality [version 1; peer review
  2906. Emerging molecular pathways governing dietary regulation of neural Stem cells during aging
  2907. Insights into the pathogenic secondary symptoms caused by the primary loss of dystrophin
  2908. Opportunities for organoids as new models of aging
  2909. RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia
  2910. Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells
  2911. Satellite cells maintain regenerative capacity but fail to repair disease-associated muscle damage in mice with Pompe disease
  2912. Characterizing a Signaling Network That Maintains Hematopoietic Stem Cells
  2913. Pediatric leukemia susceptibility disorders: manifestations and management
  2914. Genetic regulation of the RUNX transcription factor family has antitumor effects
  2915. JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML
  2916. Making gene editing a therapeutic reality
  2917. Methods of reactivation and reprogramming of neural Stem cells for neural repair
  2918. NAD+ deficits in age-related diseases and cancer
  2919. Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy
  2920. Emerging role of extracellular vesicles as a senescence-associated secretory phenotype: Insights into the pathophysiology of lung diseases
  2921. RNA processing in the male germline: mechanisms and implications for fertility
  2922. Inflammation, a significant player of Ataxia–Telangiectasia pathogenesis?
  2923. Parabiosis and Aging Researches
  2924. Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers
  2925. Biological/pathological functions of the CXCL12/CXCR4/CXCR7 axes in the pathogenesis of bladder cancer
  2926. Sepsis induces a long-lasting state of trained immunity in bone marrow monocytes
  2927. Ataxia telangiectasia mutated kinase is an autophagic balancer at the onset of heart failure
  2928. Loss of SIRT 2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
  2929. Aryl hydrocarbon receptor (AhR) ligands as selective AhR modulators: Genomic studies
  2930. HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directions
  2931. Genetics of Progeria and Aging
  2932. Evaluation of EZH2 expression in hepatitis B patients
  2933. Double sword role of EZH2 in leukemia
  2934. mTOR cross-talk in cancer and potential for combination therapy
  2935. The impact of cellular senescence in skin ageing: a notion of mosaic and therapeutic strategies
  2936. Is chronic kidney disease-mineral and bone disorder associated with the presence of endothelial progenitor cells with a calcifying phenotype?
  2937. PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing
  2938. The integration of inflammaging in age-related diseases
  2939. The energy maintenance theory of aging: maintaining energy metabolism to allow longevity
  2940. Inflammatory cytokines and comorbidity development in breast cancer survivors versus noncancer controls: evidence for accelerated aging?
  2941. Novel biallelic missense mutations in CTC1 gene identified in a Chinese family with Coats plus syndrome
  2942. The continuum of aging and age-related diseases: common mechanisms but different rates
  2943. Therapeutic potential of boosting NAD+ in aging and age-related diseases
  2944. Ayurveda and the science of aging
  2945. DICER1: A Key Player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity, and chronic inflammation in aging
  2946. Dysregulation of mesenchymal stromal cell antioxidant responses in progressive multiple sclerosis
  2947. The transcription factor Zfx regulates peripheral T cell self-renewal and proliferation
  2948. Mitochondria, its DNA and telomeres in ageing and human population
  2949. Age‐related small vessel disease: a potential contributor to neurodegeneration in multiple sclerosis
  2950. Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy
  2951. Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF
  2952. Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
  2953. Nutritional regulation of intestinal Stem cells
  2954. Targeting histone methylation in cancer
  2955. Understanding lamin proteins and their roles in aging and cardiovascular diseases
  2956. Role of endogenous glucocorticoids in cancer in the elderly
  2957. A novel stilbene-like compound that inhibits melanoma growth by regulating melanocyte differentiation and proliferation
  2958. Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and aging
  2959. Distinct roles of Wnt/β-catenin signaling in the pathogenesis of chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
  2960. Idiopathic pulmonary fibrosis
  2961. Causes of pulmonary fibrosis in the elderly
  2962. Sirtuins and accelerated aging in scleroderma
  2963. The mechanism of B cell acute lymphoblastic leukemia development
  2964. Aging of Human Mesenchymal Stem Cells
  2965. Incorporation of macrophages into engineered skeletal muscle enables enhanced muscle regeneration
  2966. Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention
  2967. Therapeutic Gene Editing in Muscles and Muscle Stem Cells
  2968. Drosophila as a model for ageing
  2969. Biphasic modeling of mitochondrial metabolism dysregulation during aging
  2970. Xenohormesis in early life: New avenues of research to explore anti-aging strategies through the maternal diet
  2971. Let-7 suppresses B cell activation through restricting the availability of necessary nutrients
  2972. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance
  2973. Histone Variant MacroH2A in the Gut and Beyond: A Study of Intestinal Fortitude
  2974. Updates from the TP53 universe
  2975. Probiotic bacteria for healthier aging: immunomodulation and metabolism of phytoestrogens
  2976. Interrelationship of canonical and non-canonical Wnt signalling pathways in chronic metabolic diseases
  2977. States of G0 and the proliferation-quiescence decision in cells, tissues and during development
  2978. COPD in the elderly: The ageing lung
  2979. Short telomeres—a hallmark of heritable cardiomyopathies
  2980. Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing
  2981. The African turquoise killifish: A research organism to study vertebrate aging and diapause
  2982. C/EBPβ is required for survival of Ly6C− monocytes
  2983. A novel functional in vitro model that recapitulates human muscle disorders
  2984. Immortality Research Literatures
  2985. Mechanisms and consequences of oxidative stress in lung disease: therapeutic implications for an aging populace
  2986. Articular cartilage repair of the knee in children and adolescents
  2987. PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions
  2988. B-cell PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA CELLS MANIPULATE MESENCHYMAL STROMAL CELLS
  2989. A regulatory role for RUNX1, RUNX3 in the maintenance of genomic integrity
  2990. Senescent cells and osteoarthritis: a painful connection
  2991. Cutaneous infections in the mature patient
  2992. Searching for a Cancer-Proof Organism: It’s the Journey That Teaches You About the Destination
  2993. Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy
  2994. Generation of induced progenitor-like (iPL) cells using interrupted reprogramming
  2995. Olive oil and skin anti-aging.
  2996. Transcriptional selectivity of epigenetic therapy in cancer
  2997. Ubiquitination by HUWE1 in tumorigenesis and beyond
  2998. Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors
  2999. Biological Determinants of Men’s Health and Aging
  3000. Aeroaging—A new collaboration between life sciences experts and aerospace engineers
  3001. Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome
  3002. Emerging roles of CST in maintaining genome stability and human disease
  3003. A virus-acquired host cytokine controls syStemic aging by antagonizing apoptosis
  3004. EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association
  3005. Ageing, cellular senescence and neurodegenerative disease
  3006. Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging
  3007. Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging
  3008. Exosomes as mediators of the syStemic adaptations to endurance exercise
  3009. Probing the pathogenesis of Duchenne muscular dystrophy using mouse models
  3010. Basic biology of oxidative stress and the cardiovascular syStem: part 1 of a 3-part series
  3011. Sex differences in aging: genomic instability
  3012. Functional genomics approaches to characterize the role of polycomb group genes in hematopoiesis
  3013. Biological predictors of aging and potential of FTIR to study age-related diseases and aging metabolic fingerprint
  3014. Ageing and ocular surface immunity
  3015. Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence
  3016. α-Synuclein pathology and mitochondrial dysfunction
  3017. Turning round: optimizing the anti-inflammatory properties of equine bone marrow derived mesenchymal Stem cells for osteoarthritis through three-dimensional culture
  3018. Autophagy and the cell cycle: a complex landscape
  3019. Application of biological age assessment of Chinese population in potential anti-ageing technology
  3020. Myeloid Translocation Gene 16 as a Determinant of Notch-driven Leukemic Phenotype
  3021. The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing
  3022. A reduction in DNA damage in neural tissue and peripheral blood of old mice treated with caffeine
  3023. Mitohormesis, an antiaging paradigm
  3024. Effects of physiological overexpression of SIRT6 in metabolism and cancer
  3025. Molecular Interaction Between the Microenvironment and FLT3/ITD+ AML Cells Leading to the Refractory Phenotype
  3026. BBA-Molecular Basis of Disease
  3027. cell cycle RNA regulons coordinating early lymphocyte development
  3028. Screening of exosomal miRNAs derived from subcutaneous and visceral adipose tissues: determination of targets for the treatment of obesity and associated …
  3029. Establishment of photoaging in vitro by repetitive UVA irradiation: Induction of characteristic markers of senescence and its prevention by PAPLAL with potent catalase …
  3030. GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis
  3031. Transcriptomic network analysis of brain aging and alzheimers disease
  3032. Dynamical analysis of cellular ageing by modeling of gene regulatory network based attractor landscape
  3033. 53BP1–RIF1–shieldin counteracts DSB resection through CST-and Polα-dependent fill-in
  3034. Regulation of Programmed Necrosis and Bone Marrow Failure
  3035. DNA and Histone Modifications in Cancer Therapy
  3036. Idiopathic pulmonary fibrosis: aging, mitochondrial dysfunction, and cellular bioenergetics
  3037. Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells
  3038. Back to the future: epigenetic clock plasticity towards healthy aging
  3039. The CST complex mediates end protection at double-strand breaks and promotes PARP inhibitor sensitivity in BRCA1-deficient cells
  3040. Age-Related Variations in Gene Expression Patterns of Renal cell Carcinoma: Biological and Translational Implications
  3041. Report: NIA workshop on measures of physiologic resiliencies in human aging
  3042. The advances and challenges of gene therapy for Duchenne muscular dystrophy
  3043. The role of COUP-TFII in striated muscle development and disease
  3044. Use of zebrafish to study Shigella infection
  3045. Aging, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks
  3046. Hallmarks of brain aging: adaptive and pathological modification by metabolic states
  3047. Transcriptional regulation of human paraoxonase 1 by nuclear receptors
  3048. The effect of Poly I: C induced inflammation on hematopoietic Stem and progenitor cell behaviour in the zebrafish hematopoietic transplant model
  3049. CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells
  3050. Retinal, NPY-and 5 ht-inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix jacchus)
  3051. Emerging molecular predictive and prognostic factors in acute myeloid leukemia
  3052. Lung tissue gene-expression signature for the ageing lung in COPD
  3053. Redox theory of aging: implications for health and disease
  3054. Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
  3055. mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation
  3056. Idiopathic pulmonary fibrosis: pathogenesis and management
  3057. Does ageing foster transformation to Acute Myeloid Leukaemia? Study of mice cohort bearing haematopoietic malignancy burden, and the effects of ageing on …
  3058. Conservation of a gene expression barcode that defines spermatogonial Stem cells in mice and humans
  3059. Expression profiling of mRNAs and long non-coding RNAs in aged mouse olfactory bulb
  3060. Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes?
  3061. Regulation of cell proliferation and differentiation by p38 MAPK in distinct physiopathological processes
  3062. Epigenetic biomarkers for biological age
  3063. Wnt signaling in bone metastasis: mechanisms and therapeutic opportunities
  3064. Telomeres and Cardiovascular Diseases
  3065. Low serum tryptophan levels as an indicator of global cognitive performance in nondemented women over 50 years of age
  3066. Deletion of mitochondrial inorganic pyrophosphatase gene extends life span in haploid yeast (Saccharomyces cerevisiae)
  3067. The epigenetic regulation of telomere maintenance in aging
  3068. STAT5BN642H is a driver mutation for T cell neoplasia
  3069. Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
  3070. The geometric framework: An approach for studying the impact of nutrition on healthy aging
  3071. Cycles of myofiber degeneration and regeneration lead to remodeling of the neuromuscular junction in two mammalian models of Duchenne muscular …
  3072. Unravelling the identity and fate of Notch1-expressing cells within intestinal tumours
  3073. Dual Roles of Fer Kinase Are Required for Proper Hematopoiesis and Vascular Endothelium Organization during Zebrafish Development
  3074. Autophagy and proteostasis in the control of synapse aging and disease
  3075. Oxidative and nitrosative stress in myeloproliferative neo-plasms: The impact on the AKT/mTOR signaling pathway
  3076. Physiological and Pathological Vascular Aging
  3077. Whole-body clearing, staining and screening of calcium deposits in the mdx mouse model of Duchenne muscular dystrophy
  3078. Comprehensive geriatric assessment: an updated perspective
  3079. EVI5 is a novel independent prognostic predictor in hepatocellular carcinoma after radical hepatectomy
  3080. Computational methods for developing novel antiaging interventions
  3081. The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells
  3082. The importance of biophysical and biochemical stimuli in dynamic skeletal muscle models
  3083. Aging-associated Changes in the DNA Methylome and Characteristics of the Epigenetic Clock
  3084. Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort
  3085. The quest for osteoporosis mechanisms and rational therapies: how far we’ve come, how much further we need to go
  3086. The Epithelial To Mesenchymal Transition In Breast Cancer Induces Alterations In Metabolism
  3087. Aging in a relativistic biological space-time
  3088. Translational Medicine of Aging
  3089. HIV/AIDS: oxidative stress and dietary antioxidants
  3090. Improvement of dystrophic muscle fragility by short-term voluntary exercise through activation of calcineurin pathway in mdx mice
  3091. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
  3092. RISKS OF BLOOD-BORNE
  3093. Development of a Duchenne Muscular Dystrophy Registry in South Africa to optimise care
  3094. Studies on the Mechanisms of DNA Damage Repair in Human Neurons
  3095. Cardiovascular Aging Compendium
  3096. Dual roles of fer kinase are required for proper hematopoiesis and vascular endothelium organization during zebrafish development
  3097. Ex Vivo Expansion of Skeletal Muscle Stem Cells with a Novel Inhibitor of eIF1α Dephosphorylation
  3098. Primary scalp alopecia: new histopathological tools, new concepts and a practical guide to diagnosis
  3099. FOXOs maintaining the equilibrium for better or for worse
  3100. Interleukin-6 affects aging-related changes of the pparα-PGC-1α axis in the myocardium
  3101. RPL5 on 1p22. 1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response
  3102. A high-throughput screening syStem to identify modulators of cancer Stem cells and improve chemotherapy sensitization
  3103. The potential of comparative biology to reveal mechanisms of aging in rotifers
  3104. Current perspective in the discovery of anti-aging agents from natural products
  3105. Brain aging: Hsp90 and neurodegenerative diseases
  3106. Stat3 and CCAAT enhancer–binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis
  3107. Hormetic induction of antioxidant defenses for promotion of healthy aging
  3108. The role of the protein SNEVhPrp19/hPso4 in function and morphology of human dermal fibroblasts and human epidermal keratinocytes
  3109. Comparison of primary human gingival fibroblasts from an older and a young donor on the evaluation of cytotoxicity of denture adhesives
  3110. Age-Associated Changes in Structure and Function of the Aging Human Lung
  3111. The impact of substance use disorders on clinical outcomes in older‐adult psychiatric inpatients
  3112. DEPTOR at the nexus of cancer, metabolism, and immunity
  3113. Transcriptome network analysis reveals aging-related mitochondrial and proteasomal dysfunction and immune activation in human thyroid
  3114. Restoring effects of natural anti-oxidant quercetin on cellular senescent human dermal fibroblasts
  3115. Using comparative biology to understand how aging affects mitochondrial metabolism
  3116. Physical activity and nutrition: two promising strategies for telomere maintenance?
  3117. der Mathematisch-Naturwissenschaftlichen Fakultät der Eberhard Karls Universität Tübingen zur Erlangung des Grades eines Doktors der Naturwissenschaften …
  3118. Dissecting host cell death programs in the pathogenesis of influenza
  3119. Characterisation of Newt Neural Stem Cells During Development and Regeneration
  3120. ICEC0942, an orally bioavailable selective inhibitor of CDK7 for cancer treatment
  3121. Targeting cell Cycle Proteins in Brain Cancer
  3122. An Analysis of the effects of Mocs1 upregulation on lifespan in Drosophila melanogaster
  3123. Pulmonary Diseases, a Matter of Time
  3124. MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction
  3125. RUNX1 cooperates with FLT3-ITD to induce leukemia
  3126. mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation
  3127. Ageing and Neurologic Disease
  3128. Recent insights into the cellular and molecular determinants of aging
  3129. The mitochondria in lung fibrosis: friend or foe?
  3130. Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging
  3131. Human CST prefers G-Rich but not necessarily telomeric sequences
  3132. Recombinant latcripin 11 of Lentinula edodes C91-3 suppresses the proliferation of various cancer cells
  3133. Translational geroscience: from invertebrate models to companion animal and human interventions
  3134. IDENTIFICATION OF INTRINSIC REGULATORS IN NORMAL AND MALIGNANT HUMAN HEMATOPOIESIS
  3135. Ataxia telangiectasia syndrome: moonlighting ATM
  3136. Differential gene expression of a feed-spiked super-producing CHO cell line
  3137. Toll-like receptor-4 signaling pathway in aorta aging and diseases:“its double nature”
  3138. Natural variations in yeast aging reveal genetic and environmental factors
  3139. Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication
  3140. Modelling the molecular mechanisms of aging
  3141. 37 kDa LRP:: FLAG enhances telomerase activity and reduces senescent markers in vitro
  3142. Periodontology for Geriatric Patients
  3143. The companion dog as a unique translational model for aging
  3144. Hematopoietic cell Engineering from Human Pluripotent Stem Cells
  3145. Changing the pathobiological paradigm in myelodysplastic syndromes: The NLRP3 inflammasome drives the MDS phenotype
  3146. Chronic obstructive pulmonary disease in elderly patients
  3147. Serine catabolism by SHMT2 is required for proper mitochondrial translation initiation and maintenance of formylmethionyl-tRNAs
  3148. Mitochondrial-targeted catalase: extended longevity and the roles in various disease models
  3149. The Role of Epigenetics
  3150. Aging as an epigenetic phenomenon
  3151. Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice
  3152. Improved immune responses in young and aged mice with adjuvanted vaccines against H1N1 influenza infection
  3153. The decay of redox-stress response capacity is a substantive characteristic of aging: revising the redox theory of aging
  3154. Hormones in clock regulation during ageing
  3155. Dictyostelium discoideum: A Model SyStem to Study Autophagy Mediated Life Extension
  3156. The mitochondrial basis of aging and age-related disorders
  3157. Novel treatment strategies for chronic kidney disease: insights from the animal kingdom
  3158. Effects of Cranial Irradiation on Adult Hippocampal Neuronal Development and the Role of p53
  3159. A null mutation in SERPINE1 protects against biological aging in humans
  3160. Hepatic potential of Reversed-age Mesenchymal Stem Cells and Endodermal Progenitors: Contribution of LGR5 and Cdc42 cell signaling pathways
  3161. Major trauma and acceleration of the ageing process
  3162. Inhibitory effect of naringenin on LPS-induced skin senescence by SIRT1 regulation in HDFs
  3163. Cellular metabolism and oxidative stress as a possible determinant for longevity in small breed and large breed dogs
  3164. Aging Pathology in Sprague Dawley Rats: Background Lesions and Comparative Study Between Wild Type and Transgenic Rats with Neuronal Overexpression of …
  3165. The Regulation of Telomerase Reverse Transcriptase (TERT) by CCAAT/Enhancer Binding Protein β (C/EBPβ) During Skeletal Muscle Differentiation
  3166. Exposure to Concentrated Ambient PM2.5 Shortens Lifespan and Induces Inflammation-Associated Signaling and Oxidative Stress in Drosophila
  3167. Exploring the mechanistic effects of life extending treatments on the mTOR network: a combined computational and experimental approach
  3168. The Role of Secreted Frizzled-related Protein-4 (sFRP4) in the Epigenetics, Metabolism and Chemo-sensitisation of Cancer Stem Cells
  3169. Does dietary nitrate say NO to cardiovascular ageing? Current evidence and implications for research
  3170. The contribution of oxidative stress and inflamm-aging in human and equine asthma
  3171. Unraveling novel genes that are essential for acute myeloid leukemia and normal hematopoiesis
  3172. Targeting aging and Alzheimer’s disease: from GM1 ganglioside to amyloide-β peptide
  3173. Effects of resveratrol and other polyphenols on Sirt1: relevance to brain function during aging
  3174. The role of free radicals in autophagy regulation: implications for ageing
  3175. The role of endocannabinoid syStem in neuron-glial communication in the ageing and diseased brain
  3176. Current Perspective in the Discovery of Anti-aging Agents from Natural Products
  3177. When nature’s robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies
  3178. Age-associated inflammation impairs myeloid development and monocyte and macrophage function
  3179. The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature
  3180. The Cellular And Molecular Underpinnings Of Intestinal Epithelial Regeneration
  3181. Identification of LRP8, CDCA7, and MLK4 as Novel Therapeutic Targets for Cancer Stem Cells in Triple-Negative Breast Cancer
  3182. Aging kidney and aging-related disease
  3183. Stage-specific changes in the Krebs cycle network regulate human erythroid differentiation
  3184. Targeting mitochondria to counteract age-related cellular dysfunction
  3185. Parallels in immunometabolic adipose tissue dysfunction with ageing and obesity
  3186. Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
  3187. Insights into mortality patterns and causes of death through a process point of view model
  3188. The chromatin accessibility signature of aging in human blood leukocytes Stem from CD8+ T cells.
  3189. CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance
  3190. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function
  3191. Pathogenic CTC1 mutations cause global genome instabilities under replication stress
  3192. Autophagy in age-associated neurodegeneration
  3193. DNA Damage-related Vascular Dysfunction: Pathways and Interventions
  3194. DNA replication origins and fork progression at mammalian telomeres
  3195. Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research–a consensus document from six …
  3196. DNA methylation–based measures of biological aging
  3197. Characterizing the Role of the E3 Ligase ITCH in Gut Mucosal Homeostasis
  3198. Holothuria scabra extracts possess anti-oxidant activity and promote stress resistance and lifespan extension in Caenorhabditis elegans
  3199. Functional Identification of MicroRNAs Counteracting Cellular Senescence
  3200. Healthy at 100: Genetic factors and phenotypes associated with healthy aging and longevity
  3201. Senescence Induced by DNA Demethylating Drugs to Treat Solid Tumors
  3202. Protein posttranslational modifications: roles in aging and age-related disease
  3203. Pathogenesis of COPD 4–cell Death, Senescence, and Autophagy: Is There a Possibility of Developing New Drugs from the Standpoint of This Pathogenetic …
  3204. Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism
  3205. The Potential Detrimental Impact of Galactic Cosmic Radiation on Central Nervous SyStem and Hematopoietic Stem Cells
  3206. Identification of affected pro-atherogenic gene targets in Prog-Tg mice and endothelial cells
  3207. Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts
  3208. Onset and progression of human osteoarthritis—Can growth factors, inflammatory cytokines, or differential miRNA expression concomitantly induce proliferation, ECM …
  3209. The therapeutic potential of metformin in neurodegenerative diseases
  3210. Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans
  3211. Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes
  3212. Exploring the biochemistry of the prenylome and its role in disease through proteomics: progress and potential
  3213. Cognitive impairment in chronic obstructive pulmonary disease (COPD): Possible utility of marine bioactive compounds
  3214. Mitotic chromosome alignment is required for proper nuclear envelope reassembly
  3215. The role of P53 signaling pathway in aging and cancer
  3216. MicroRNAs and the metabolic hallmarks of aging
  3217. Analysis of phenotype reversibility in Hutchinson-Gilford progeria syndrome in mice
  3218. Ophthalmologic features of Hutchinson-Gilford Progeria syndrome
  3219. Role of autophagy in normal and malignant hematopoiesis
  3220. Remodeling of the extracellular matrix in COPD. a process of accelerated lung ageing?
  3221. Novel targets for delaying aging: the importance of the liver and advances in drug delivery
  3222. JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21
  3223. STUDY OF OXIDATIVE STRESS AND ANTIOXIDANT RESPONSE IN THE SGCA NULL DYSTROPHIC MOUSE MODEL
  3224. The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication
  3225. Alterations in Autophagy and Senescence in the Pathologically Aged Uraemic Heart
  3226. Healthy human aging: intrinsic and environmental factors
  3227. The role of melanocyte senescence in skin ageing
  3228. ZBTB 48 is both a vertebrate telomere‐binding protein and a transcriptional activator
  3229. Role of inflammation and oxidative stress in the pathology of ageing in COPD: potential therapeutic interventions
  3230. Membrane Lipid Replacement for chronic illnesses, aging and cancer using oral glycerolphospholipid formulations with fructooligosaccharides to restore …
  3231. RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions
  3232. Interrelation of mitochondrial DNA and telomere length alterations in ageing human population
  3233. CRISPR-Cas9 mutagenesis of the zebrafish foxm1
  3234. Host-Pathogen Interactions at the Intestinal Epithelial Barrier
  3235. Effects of resveratrol and other polyphenols on the most common brain age-related diseases
  3236. Targeting the antagonism of AHR by MSI2 as a novel anti-leukemic strategy in human acute myeloid leukemia
  3237. Phosphorylation dependent structural function of DNA-PKcs in DNA repair and hematopoiesis
  3238. Transdifferentiation in Turritopsis dohrnii (Immortal Jellyfish): Model SyStem for Regeneration, Cellular Plasticity and Aging
  3239. Regulation and Consequences of Retrotransposition During Quiescence in Budding Yeast
  3240. DNA damage and oxidative stress in long-lived aquatic organisms
  3241. Modeling Tuberous Sclerosis Complex Using Patient-Derived Cells
  3242. Telomere dynamics and cellular senescence: an emerging field in environmental and occupational toxicology
  3243. Investigating the Role of the Chromatin Factor SIRT6 in Metabolism of Squamous cell Carcinoma
  3244. Rodak’s hematology: clinical principles and applications
  3245. Characterization of epigenetic and transcriptional changes in aging and Alzheimer’s disease
  3246. Circadian Mechanisms of Calorie Restriction in Delaying Aging
  3247. Delineating Transcriptional and Epigenetic Regulations in Normal and Ageing Spermatogonial Stem Cells
  3248. Quantitative telomeric chromatin isolation protocol for human cells
  3249. Epigenetics and aging research: Between adult malleability and early life programming
  3250. STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1
  3251. Autophagy and microglia: novel partners in neurodegeneration and aging
  3252. Circulating levels of soluble Receptor for Advanced Glycation End-products (sRAGE) decrease with aging and may predict age-related cardiac remodeling
  3253. Correlation Between Epstein-Barr Virus Infection and The Severity of Malaria in Ghanaian Children Under Five (5) Years of Age
  3254. Human life extension: opportunities, challenges, and implications for public health policy
  3255. Zebrafish aging models and possible interventions
  3256. Defining a Quiescent Tumor Propagating cell State in Squamous cell Carcinoma
  3257. The early events that initiate β-amyloid aggregation in Alzheimer’s disease
  3258. Non-coding RNA regulation of T cell biology: implications for age-associated cardiovascular diseases
  3259. Bioactive growth hormone in older men and women: It’s relationship to immune markers and healthspan
  3260. PGC-1α in neurodegeneration and ageing
  3261. Adult neurogenesis in a diurnal vertebrate: from hours to years
  3262. Effects of Novel Aging-Delaying Plant Extracts on the Lipid Composition of the Yeast Saccharomyces Cerevisiae
  3263. Unraveling the link between the Mdm2-p53 axis and aging
  3264. Investigating the Relationship Between DNA Damage and Hormesis in Saccharomyces cerevisiae Chronological Aging
  3265. Mammalian CST averts replication failure by preventing G-quadruplex accumulation
  3266. SyStems Biology Interrogation of Mammalian Cellular Metabolism
  3267. Elucidating The Role Of Type I Interferon Signaling In Adipocyte Biology
  3268. MORPHOLOGIC AND CYTOMETRIC EVALUATION OF ANEMIA IN GERIATRIC PATIENTS
  3269. Mitochondria Dictate Biological Outcomes in Malignancy, Regeneration and Immunity.
  3270. Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs
  3271. Role of Human Endogenous Retrovirus type K (HERV-K) in immunosenescence: RNA-seq based transcriptomic analysis
  3272. 2 Understanding Aging
  3273. Theories of Individual Ageing
  3274. G protein-coupled receptor syStems as crucial regulators of DNA damage response processes
  3275. The aging immune syStem and nutritional interventions
  3276. I would like to thank my advisor, Raymond Page for all of his help, support, mentoring, and guidance over the course of my project. I would like to thank my …
  3277. Self-Eating on Demand: Autophagy in Cancer and Cancer Therapy
  3278. Effect of novel ryanodine receptor modulators in mouse and human models of Duchenne muscular dystrophy
  3279. Telomeres, diet and human disease: advances and therapeutic opportunities
  3280. Major Lifestyles and Phenotypes in Aging and Disease
  3281. Discovering Rare Hematopoietic Clones Harboring Leukemia-Associated Mutations Using Error-Corrected Sequencing
  3282. Store-operated calcium entry in adult mice ventricular cardiomyocytes
  3283. The hepatic fate of vitamin E
  3284. Glycogen regulates cellular proliferation in the context of aging, tumorigenesis, and hepatic regeneration
  3285. When evolution is the solution to pollution: Key principles, and lessons from rapid repeated
  3286. Medical Industry Cluster Promotion Unit Commerce, Industry & Labour Department Fukushima Prefectural Government
  3287. Investigating the Role of Epithelial-mesenchymal Crosstalk in the Pathology of Idiopathic Pulmonary Fibrosis
  3288. From Neurons to Transcription Factors: the Biological Regulation of Aging
  3289. The Role of Homeobox Transcription Cofactors in Prostate Development and Tumor Growth
  3290. The Human Brain as a Mosaic: Somatic Mutation in Autism Spectrum Disorder, Aging, and Neurodegeneration
  3291. The Role of Nrf2 in the Activation of Primary CD4 T Cells from Mice and Humans
  3292. Elucidating the role of synucleins in retinal neurodegeneration in Parkinson’s Disease, Diabetes and Ageing
  3293. MOLECULAR SIGNATURES AND MECHANISMS BEHIND LIFESPAN EXTENSION
  3294. CMGC kinases and Cancer
  3295. The consequences of mutator-driven mutagenesis and analysis of lifespan extending compounds using outgrowth analysis and replicative lifespan in Saccharomyces …
  3296. Transitions between care settings until death
  3297. Characterization of the DNA Binding Properties of CST (CTC1-STN1-TEN1) And Their Importance for CST Function in Telomeric as well as Genome-wide Replication
  3298. Relative roles of UBF and RRN3 in the transcription of the ribosomal RNA genes and ribosome biogenesis determined using in vivo mouse models
  3299. human health
  3300. SARCOPENIC OBESITY IN SCOTISH OLDER COMMUNITY-DWELLERS: A WEIGHT LOSS INTERVENTION USING HIGH PROTEIN INTAKE AND MIXED EXERCISE …
  3301. Crosstalk of gene polymorphisms with RNA and protein phenotypic characteristics
  3302. T-ALLAssociated NAP1L1-MLLT10 Fusion Protein Promotes Telomerase-Mediated Telomrere Elongation
  3303. Investigating homeostatic disruption by constitutive signals during biological ageing
  3304. Intervertebral Disc Inflammation: The Effect Of Il-1ra Deficiency On Development, Aging And Injury Of The Murine Caudal Intervertebral Disc
  3305. Medication, Exercise and Quality of Life in Older Adults
  3306. Role of NLRP3-inflammasone in functional decline in physiological aging. Implications for cardio-metabolic events.
  3307. Longevity, aging and DNA damage: investigation of the role of 53BP1 in the maintenance of genomic stability
  3308. Ageing, inorganic nitrate and vitamin C: effects on markers of cardiovascular risk
  3309. Neurochemical aspects of Alzheimer’s disease: risk factors, pathogenesis, biomarkers, and potential treatment strategies
  3310. The effect of age on brain insulin signalling
  3311. Dietary patterns and whole plant foods in aging and disease
  3312. Telomeric double strand breaks undergo resection-but not repair-in G1 human cells
  3313. Aging and microRNA messaging: associations with syStemic estrogen levels and physical performance
  3314. Development and application of RNA-seq bioinformatic tools to explore non-model organisms in ageing research
  3315. Alternative formats
  3316. Plasticity of Antioxidant Defense Pathways in Response to Aging and Cadmium in Glutathione-Deficient Mice
  3317. On Aging: Analyses of Long-term Fine Particulate Air Pollution Exposure, Genetic Variants, and Blood DNA Methylation Age in the Elderly
  3318. Identifying Genetic Factors Involved in Aging and Neurodegeneration
  3319. The Role of microRNAs in Drosophila Circadian Rhythms and Aging and Genome-wide Identification of Activity-regulated Genes
  3320. Functional Genomics of Ageing and Its Modulation by Diet
  3321. Effects of AMP-activated kinase modulators on intracellular Ca2+ signalling and C. elegans lifespan
  3322. The Ultrastructural and Abnormal Calcium Handling in Pulmonary Vein Sleeve Cells, Atrial and Ventricular Myocytes During Ageing
  3323. Immunomodulation by raw bovine milk and its ingredients: effects in nutritional intervention, oral vaccination and trained immunity
  3324. The Role of Histone 3 Lysine 4 Methylation in Ageing and Stress Resistance
  3325. The BARD1 BRCT Domain in Tumor Suppression and Genome Stability
  3326. Glycogen Enhancement Augments Overload-Induced Protein Synthesis, Growth, and Myogenesis in Aged Skeletal Muscle
  3327. Neuronal p38α mediates age‐associated neural Stem cell exhaustion and cognitive decline
  3328. Vascular regenerative cell exhaustion in diabetes: translational opportunities to mitigate cardiometabolic risk
  3329. Disruption of the Normal Hematopoietic Hierarchy Leading to Stem cell exhaustion in an Animal Model of Myelodysplastic Syndrome
  3330. Adult Stem cell deficits drive Slc29a3 disorders in mice
  3331. Telomere shortening as a hallmark of Stem cell senescence
  3332. Zika virus and the metabolism of neuronal cells
  3333. The epigenetics of Stem cell aging comes of age
  3334. Adult cardiac Stem cell aging: a reversible stochastic phenomenon?
  3335. Advances in Stem cell Research in Sepsis 17
  3336. Electroporation-mediated HGF gene transfer increases mesenchymal Stem cell and decreases MMP24 levels in a bleomycin-induced lung injury model
  3337. Advances in Stem cell Research in Sepsis
  3338. Ageing as a risk factor for neurodegenerative disease
  3339. PS1567 UNCOUPLING INK PROTEINS FROM CDK4/CDK6 IN HSCS–UNCOUPLING PROLIFERATION FROM SENESCENCE
  3340. Role of hypothalamus in aging and its underlying cellular mechanisms
  3341. Losing sense of self and surroundings: hematopoietic Stem cell aging and leukemic transformation
  3342. TGFB signaling disruption in the formation of oral pre-neoplasia
  3343. Modeling Fanconi Anemia in Squamous Epithelium using Human Induced Pluripotent Stem cell -Derived Organoids
  3344. TRiC activates the unfolded protein response and protects starved Stem cells by modulating energy and lipid metabolism during planarian regeneration
  3345. The circadian clock in adult neural Stem cell maintenance
  3346. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal Stem cells
  3347. Epigenetic regulation of bone marrow Stem cell aging: revealing epigenetic signatures associated with hematopoietic and mesenchymal Stem cell aging
  3348. Application of mtor inhibitors in extending longevity
  3349. Epigenetic regulation of hematopoietic Stem cell homeostasis
  3350. Inflamm-aging of hematopoietic Stem cells
  3351. Mitochondrial metabolism and the maintenance of hematopoietic Stem cell quiescence
  3352. Stem cell quiescence: dynamism, restraint, and cellular idling
  3353. Accelerated lung aging and chronic obstructive pulmonary disease
  3354. Mitochondrial dysfunction and aging: Insights from the analysis of extracellular vesicles
  3355. mTOR and aging: an old fashioned dress
  3356. Derivation of an aged mouse induced pluripotent Stem cell line, IISHDOi005-A
  3357. Allogeneic mesenchymal Stem cell therapy: A regenerative medicine approach to geroscience
  3358. Proteinase activated receptor 2 modulates expression of autophagy markers in murine lungs
  3359. Because age matters–A comparative multi-omics analysis of young and old mice in the Bleomycin-induced lung fibrosis model
  3360. Asrij/OCIAD1 suppresses CSN5-mediated p53 degradation and maintains mouse hematopoietic Stem cell quiescence
  3361. Stem cell –driven lymphatic remodeling coordinates tissue regeneration
  3362. Pulmonary diseases and ageing
  3363. The transcription factor Slug represses p16Ink4a and regulates murine muscle Stem cell aging
  3364. Challenges and Opportunities for the Future of Stem cell Therapy for Lung Diseases
  3365. Phase I/II study of Stem–cell transplantation using a single cord blood unit expanded ex vivo with nicotinamide
  3366. Mathematical modeling to study multistage Stem cell transplantation in HIV-1 patients
  3367. CDK4/6 inhibition mitigates Stem cell damage in a novel model for taxane‐induced alopecia
  3368. Hematopoietic Stem cell heterogeneity
  3369. Investigating Neural Stem cell Function in an Alzheimer’s Disease Model
  3370. Juel Rasmussen Group
  3371. The NAD-booster nicotinamide riboside potently stimulates hematopoiesis through increased mitochondrial clearance
  3372. Causes and mechanisms of hematopoietic Stem cell aging
  3373. Regulatory mechanisms and clinical manifestations of musculoskeletal aging
  3374. Senolytics and senostatics: a two-pronged approach to target cellular senescence for delaying aging and age-related diseases
  3375. Aging and lineage allocation changes of bone marrow skeletal (stromal) Stem cells
  3376. Diffuse Parenchymal Lung Disease: A Clinical Overview
  3377. Frailty and rejuvenation with Stem cells: therapeutic opportunities and clinical challenges
  3378. A Stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia Stem cell latency
  3379. Tumor cell Dormancy—Triggered by the Niche
  3380. Redox regulation by NRF2 in aging and disease
  3381. Divide and conquer: two Stem cell populations in squamous epithelia, reserves and the active duty forces
  3382. Idiopathic Pulmonary Fibrosis
  3383. Decelerating ageing and biological clocks by autophagy
  3384. Novel approaches targeting mitochondrial fission to deplete Stem-like tumor cells in prostate cancer and improve treatment outcomes
  3385. Loss of postnatal quiescence of neural Stem cells through mTOR activation upon genetic removal of cysteine string protein-α
  3386. The aging thyroid: a reappraisal within the geroscience integrated perspective
  3387. Molecular regulation of spermatogonial Stem cell renewal and differentiation
  3388. SIRT1 is dispensable for maturation of hematopoietic Stem cell in the bone marrow niche
  3389. Stem cell competition orchestrates skin homeostasis and ageing
  3390. Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
  3391. Pluripotent Stem Cells for Gene Therapy of Hereditary Muscle Disorders
  3392. Treg-cell control of a CXCL5-IL-17 inflammatory axis promotes hair-follicle-Stem–cell differentiation during skin-barrier repair
  3393. Identification of EOMES-expressing spermatogonial Stem cells and their regulation by PLZF
  3394. Primary cilium and brain aging: role in neural Stem cells, neurodegenerative diseases and glioblastoma
  3395. EGFR-Aurka signaling rescues polarity and regeneration defects in dystrophin-deficient muscle Stem cells by increasing asymmetric divisions
  3396. Effect of graft-versus-host disease prophylaxis regimens on T and B cell reconstitution after allogeneic hematopoietic Stem cell transplantation
  3397. Epigenetic control of mitochondrial fission enables self-renewal of Stem-like tumor cells in human prostate cancer
  3398. Ptpn21 controls hematopoietic Stem cell homeostasis and biomechanics
  3399. Polycomb/trithorax antagonism: cellular memory in Stem cell fate and function
  3400. Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases
  3401. Skeletal muscle Stem cell self-renewal and differentiation kinetics revealed by EdU lineage tracing during regeneration
  3402. Flavonoids and reduction of cardiovascular disease (CVD) in chronic obstructive pulmonary disease (COPD)
  3403. CABLES1 deficiency impairs quiescence and stress responses of hematopoietic Stem cells in intrinsic and extrinsic manners
  3404. Impact of Endogenous Genomic Damage on Adult Stem Cells and Tissue Homeostasis
  3405. Loss of PRC1 activity in different Stem cell compartments activates a common transcriptional program with cell type–dependent outcomes
  3406. Senescence phenomena and metabolic alteration in mesenchymal stromal cells from a mouse model of Rett syndrome
  3407. Roles of angiopoietin-like proteins in regulation of Stem cell activity
  3408. Association of aplastic anaemia and lymphoma: a report from the severe aplastic anaemia working party of the European Society of Blood and Bone Marrow …
  3409. Maintenance of nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis
  3410. Mesenchymal niche-specific expression of Cxcl12 controls quiescence of treatment-resistant leukemia Stem cells
  3411. Mesenchymal Stem cell secretion of SDF-1α modulates endothelial function in dilated cardiomyopathy
  3412. A Phase I/II Study of Stem cell Transplantation Using a Single Cord Blood Unit Expanded Ex vivo with Nicotinamide Running Title: Nicotinamide-Expanded …
  3413. Telomere and its role in the aging pathways: telomere shortening, cell senescence and mitochondria dysfunction
  3414. Epithelial–mesenchymal transition in the pathogenesis of idiopathic pulmonary fibrosis
  3415. FGF10-FGFR2B signaling generates basal cells and drives alveolar epithelial regeneration by bronchial epithelial Stem cells after lung injury
  3416. C/EBPβ is a critical mediator of IFN-α–induced exhaustion of chronic myeloid leukemia Stem cells
  3417. Insights into human development and disease from human pluripotent Stem cell derived intestinal organoids
  3418. PI3K alpha and delta promote hematopoietic Stem cell activation
  3419. Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells
  3420. Transcription factor USF1 is required for maintenance of germline Stem cells in male mice
  3421. Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal Stem cells
  3422. Paracrine Interaction of Cancer Stem cell Populations Is Regulated by the Senescence-Associated Secretory Phenotype (SASP)
  3423. Metformin restores CNS remyelination capacity by rejuvenating aged Stem cells
  3424. Adult neural Stem cells: born to last
  3425. The 14q32. 31 DLK1-DIO3 MIR300 tumor suppressor promotes leukemogenesis by inducing cancer Stem cell quiescence and inhibiting NK cell anti-cancer immunity
  3426. Accumulation of progerin affects the symmetry of cell division and is associated with impaired Wnt signaling and the mislocalization of nuclear envelope …
  3427. Posttransplant hemophagocytic lymphohistiocytosis driven by myeloid cytokines and vicious cycles of T-cell and macrophage activation in humanized mice
  3428. mTOR as a central regulator of lifespan and aging
  3429. WUSCHEL acts as an auxin response rheostat to maintain apical Stem cells in Arabidopsis
  3430. AMPK Restrains Epidermal Stem cell Aging by Inhibiting mTORC1-Induced Hyper-Proliferation
  3431. Bone marrow mesenchymal Stem cells: Aging and tissue engineering applications to enhance bone healing
  3432. Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation
  3433. Attenuation of frailty in older adults with mesenchymal Stem cells
  3434. Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis
  3435. Mesenchymal Stem cells in homeostasis and syStemic diseases: hypothesis, evidences, and therapeutic opportunities
  3436. Increased Ripk1-mediated bone marrow necroptosis leads to myelodysplasia and bone marrow failure in mice
  3437. Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells
  3438. Metformin delays satellite cell activation and maintains quiescence
  3439. Is cellular senescence involved in cystic fibrosis?
  3440. cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of robust organismal rejuvenation
  3441. Implications of aging in plastic surgery
  3442. Niche-specific factors dynamically regulate sebaceous gland Stem cells in the skin
  3443. Role of physical exercise in the regulation of epigenetic mechanisms in inflammation, cancer, neurodegenerative diseases, and aging process
  3444. Turning back time with emerging rejuvenation strategies
  3445. The regenerating skeletal muscle niche guides muscle Stem cell self-renewal
  3446. Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?
  3447. Role of EZH2 in cell lineage determination and relative signaling pathways
  3448. From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs
  3449. Nad+ and aging: a focus on novel molecular mechanisms of werner syndrome
  3450. Age-related gene and miRNA expression changes in airways of healthy individuals
  3451. Molecular mechanisms of p63-mediated squamous cancer pathogenesis
  3452. Measuring aging and identifying aging phenotypes in cancer survivors
  3453. Longevity Research: Theological Implications
  3454. Attenuated Acceleration to Leukemia after Ezh2 Loss in Nup98-HoxD13 (NHD13) Myelodysplastic Syndrome
  3455. WUSCHEL acts as a rheostat on the auxin pathway to maintain apical Stem cells in Arabidopsis
  3456. Centenarians overexpress pluripotency-related genes
  3457. Lipotoxicity, aging, and muscle contractility: does fiber type matter?
  3458. Impacts of dietary obesity on muscle Stem cell behaviors
  3459. Nutrient sensing and redox balance: GCN2 as a new integrator in aging
  3460. Characterization of mesoangioblast cell fate and improved promyogenic potential of a satellite cell -like subpopulation upon transplantation in dystrophic …
  3461. Critical reappraisal of underlying histological patterns in patients with suspected idiopathic pulmonary fibrosis
  3462. Myelofibrosis in 2019: moving beyond JAK2 inhibition
  3463. CRISPR/Cas9 technology in restoring dystrophin expression in iPSC-derived muscle progenitors
  3464. Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation
  3465. Effects of minocycline and rapamycin in gamma-irradiated human embryonic Stem cells-derived cerebral organoids
  3466. Activation of the resident Skeletal Stem cell (SSC) for articular cartilage regeneration.
  3467. NUCLEAR SEGREGATION OF RNA AS A POTENTIAL NOVEL MARKER AND REGULATION MECHANISM OF QUIESCENCE IN NEURAL Stem cell
  3468. Potential therapies using myogenic Stem cells combined with bio-engineering approaches for treatment of muscular dystrophies
  3469. Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging
  3470. Stem cells under the influence of alcohol: effects of ethanol consumption on Stem/progenitor cells
  3471. Skin aging: The dermal perspective
  3472. Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis
  3473. In vitro and in vivo evaluation of possible pro-survival activities of PGE2, EGF, TPO and FLT3L on human hematopoiesis
  3474. Obesity may accelerate the aging process
  3475. Obesity-associated hypermetabolism and accelerated senescence of bone marrow stromal Stem cells suggest a potential mechanism for bone fragility
  3476. CRISPR/Cas9-based dystrophin restoration reveals a novel role for dystrophin in bioenergetics and stress resistance of muscle progenitors
  3477. Autophagy in hematopoietic Stem cells
  3478. New insights into the role of epithelial–mesenchymal transition during aging
  3479. Germline genetic predisposition to myeloid neoplasia from GATA2 gene mutations: lessons learned from two cases
  3480. Maintenance of nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis
  3481. Inhibiting the BMP Pathway Rescues Neural Stem cell Defects in Alzheimer’s Disease
  3482. Aging alters transcriptional circuitries and SLUG-mediated cellular states of mouse mammary epithelium
  3483. cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of comprehensive organismal rejuvenation
  3484. Translating HSC niche biology for clinical applications
  3485. MDS-associated mutations in germline GATA2 mutated patients with hematologic manifestations
  3486. NKAP regulates senescence and cell death pathways in hematopoietic progenitors
  3487. Histone H3 K4/9/27 Trimethylation Levels Regulate Wound Healing and Stem cell Dynamics in Adult Skin
  3488. Cellular senescence in cardiac diseases
  3489. Mesenchymal Stem cells targeting PI3K/AKT pathway in leukemic model
  3490. Why does an aging smoker’s lung develop idiopathic pulmonary fibrosis and not chronic obstructive pulmonary disease?
  3491. Plausible links between metabolic networks, Stem cells, and longevity
  3492. Hematopoietic Stem cells: self-renewal and expansion
  3493. Panel T17P01-Session I
  3494. Cancer Stem cells
  3495. Mesenchymal Stem Cells Inhibit Apoptosis Via Modulating AKT/Mtor Signaling Pathway in Radiation-Induced Bone Marrow Injury
  3496. Latest advances in aging research and drug discovery
  3497. Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t (12; 21) preleukemia
  3498. Development of Gold Nanorod NIR Active Surfaces for Human Mesenchymal Stem cell Detachment
  3499. The diet and the damage done
  3500. Epigenetic aging clocks in ecology and evolution
  3501. ADVANCEMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY IN RELATION TO PUBLIC HEALTH
  3502. Models and studies of aging: Executive summary of a report from the U13 conference series
  3503. Hypoxia and aging
  3504. Stem cell Signaling and RNA Regulation in Regenerating Skeletal Muscle
  3505. Adaptive endoplasmic reticulum stress signalling via IRE1α–XBP1 preserves self-renewal of haematopoietic and pre-leukaemic Stem cells
  3506. Insulin signaling in bone marrow adipocytes
  3507. Haematopoietic Stem cells in perisinusoidal niches are protected from ageing
  3508. SOX2 expression diminishes with ageing in several tissues in mice and humans
  3509. Quiescence entry, maintenance, and exit in adult Stem cells
  3510. An interview with Gary D Hammer, MD, PhD
  3511. The role of decidual mesenchymal Stem/stromal cell ageing in labour
  3512. Healthy and pathological neurocognitive aging: spectral and functional connectivity analyses using magnetoencephalography
  3513. Epigenetic changes as a target in aging haematopoietic Stem cells and age-related malignancies
  3514. Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase
  3515. When the skin is in the center of interest: An aging issue
  3516. Basic and translational aging research in China: present and future
  3517. Characterizing the Induction of Senescence by Tau and Beta-Amyloid in Rat Astrocytes
  3518. A microcavity array-based 4D cell culture platform
  3519. Regenerative medicine in the digital age
  3520. Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5
  3521. Aging, lifestyle and dementia
  3522. Embrace the fat when getting old
  3523. The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
  3524. Stimulation of hair growth by small molecules that activate autophagy
  3525. DNA damage responses in ageing
  3526. Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet
  3527. Telomerase reverse transcriptase (TERT) in action: cross-talking with epigenetics
  3528. A multi-institutional comparison of younger and older adults with sickle cell disease
  3529. Hematologic improvement with iron chelation therapy in myelodysplastic syndromes: Clinical data, potential mechanisms, and outstanding questions
  3530. Transient inhibition of mTORC1 signaling ameliorates irradiation-induced liver damage
  3531. The genetics of aging: a vertebrate perspective
  3532. Distinct patterns of hair graft survival after transplantation into 2 nonhealing ulcers: is location everything?
  3533. Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
  3534. Translational control during developmental transitions
  3535. Partial Reprogramming: A Shortcut to Rejuvenation
  3536. Astrocyte senescence: evidence and significance
  3537. Neurogenesis and brain aging
  3538. Update on the pathogenesis of chronic obstructive pulmonary disease
  3539. Embryonic Stem cells modulate the cancer-permissive microenvironment of human uveal melanoma
  3540. Inflammatory bone marrow microenvironment
  3541. The clinical impact and biological mechanisms of skeletal muscle aging
  3542. Age-related schwannomatosis with potential exosome-mediated contribution to prostate hyperplasia: a case report and mini-review
  3543. Cytological and molecular aspects of the ageing sperm
  3544. Cellular senescence as a mechanism and target in chronic lung diseases
  3545. Global transcriptomic profiling of the bone marrow stromal microenvironment during postnatal development, aging, and inflammation
  3546. Preventing epidermal jet lag by resetting the circadian clock
  3547. mTORC1 activity is essential for erythropoiesis and B cell lineage commitment
  3548. Imaging in idiopathic pulmonary fibrosis: diagnosis and mimics
  3549. The lysosome as a cellular centre for signalling, metabolism and quality control
  3550. Frailty: what the South African surgeon needs to know
  3551. Long noncoding transcriptome in chronic obstructive pulmonary disease
  3552. The transcription factor Hey and nuclear lamins specify and maintain cell identity
  3553. Checkpoint kinase 1 is essential for fetal and adult hematopoiesis
  3554. The ezh2(sa1199) mutant zebrafish display no distinct phenotype
  3555. On the fly: recent progress on autophagy and aging in Drosophila
  3556. www. aging-us. com AGING 2019, Vol. 11, Advance
  3557. Signaling pathways in leukemic Stem cells
  3558. Modulation of bone and marrow niche by cholesterol
  3559. Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence
  3560. Plasma-based strategies for therapeutic modulation of brain aging
  3561. The consequences of ageing, progeroid syndromes and cellular senescence on mechanotransduction and the nucleus
  3562. Potential role of E4orf1 protein in aging-associated impairment in glycemic control
  3563. Autophagy and Tumorigenesis in Drosophila
  3564. Extrinsic regulation of fate choice in mouse haematopoietic Stem cells
  3565. Royal jelly and its components promote healthy aging and longevity: from animal models to humans
  3566. Mechanisms of cellular rejuvenation
  3567. The unexpected noncatalytic roles of histone modifiers in development and disease
  3568. Environmental factors in successful aging: the potential impact of air pollution
  3569. The role of lipids in aging-related metabolic changes
  3570. The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo
  3571. Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy
  3572. Expression and prognosis analyses of runt-related transcription factor family in human leukemia
  3573. Muscle Stem cells give rise to rhabdomyosarcomas in a severe mouse model of Duchenne muscular dystrophy
  3574. Polycomb complexes in normal and malignant hematopoiesis
  3575. Leukemia Stem cells in hematologic malignancies
  3576. ZEB1 protects skeletal muscle from damage and is required for its regeneration
  3577. The E3 ubiquitin ligase SPOP controls resolution of syStemic inflammation by triggering MYD88 degradation
  3578. CBX7 Induces Self-Renewal of human normal and malignant hematopoietic Stem and progenitor cells by canonical and Non-canonical interactions
  3579. Enhanced therapeutic potential of the secretome released from adipose-derived Stem cells by PGC-1α-driven upregulation of mitochondrial proliferation
  3580. Future cell and gene therapy for osteoarthritis (OA): potential for using mammalian protein production platforms, irradiated and transfected protein packaging …
  3581. Senolytics and senostatics as adjuvant tumour therapy
  3582. Zika Virus Infection: Review Of Neuroimage Studies And The Relationship Between Findings And Time Of Infection
  3583. microRNAs: epigenetic players in cancer and aging
  3584. Epigenetic silencing of miRNA-338-5p and miRNA-421 drives SPINK1-positive prostate cancer
  3585. The aging lung and idiopathic pulmonary fibrosis
  3586. The human lung cell atlas: a high-resolution reference map of the human lung in health and disease
  3587. Targeting angiogenesis in Duchenne muscular dystrophy
  3588. Epigenetic reprogramming and emerging epigenetic therapies in CML
  3589. Mouse models in modeling aging and cancer
  3590. Freshwater Cnidarian Hydra: A Long-lived Model for Aging Studies
  3591. Synovium-derived mesenchymal Stem/stromal cells and their promise for cartilage regeneration
  3592. DNA methylation aging clocks: challenges and recommendations
  3593. Past, present, and future of circ RNA s
  3594. Myelodysplastic syndromes and idiopathic pulmonary fibrosis: a dangerous liaison
  3595. p21 in cancer research
  3596. A novel mammalian PIWI protein regulates self-renewal and lifespan of macrophages
  3597. Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics
  3598. Priming mobilization of hair follicle Stem cells triggers permanent loss of regeneration after alkylating chemotherapy
  3599. Latest Advances in Aging Research and Drug Discovery
  3600. Muscle contracture and passive mechanics in cerebral palsy
  3601. Epigenetic Regulation of Muscle Stem Cells During Skeletal Muscle Regeneration and Disease
  3602. Hallmarks of aging in the liver
  3603. Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy
  3604. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis
  3605. The role of miR-210 in the biological syStem: a current overview
  3606. MicroRNA function in megakaryocytes
  3607. Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke
  3608. Report of the Signal Transduction Society Meeting 2018—Signaling: From Past to Future
  3609. The neuroprotective effect of bisperoxovandium (pyridin-2-squaramide) in intracerebral hemorrhage
  3610. Interleukin-23 receptor signaling mediates cancer dormancy and radioresistance in human esophageal squamous carcinoma cells via the Wnt/Notch pathway
  3611. Interfering with bromodomain epigenome readers as therapeutic option in mucoepidermoid carcinoma
  3612. Extending Healthy Human Lifespan Using Gene Therapy
  3613. Age-related alterations affecting the chondrogenic differentiation of synovial fluid mesenchymal stromal cells in an equine model
  3614. cell senescence in lupus
  3615. Putative role of nuclear factor-kappa B but not hypoxia-inducible factor-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic Stem and progenitor …
  3616. Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults
  3617. p21cip1/waf1 coordinates autophagy, proliferation and apoptosis in response to metabolic stress
  3618. Pericytes in muscular dystrophies
  3619. DNA damage responses in ageing.
  3620. Adaptive immunodeficiency in WHIM syndrome
  3621. Adult T-type lymphoblastic lymphoma presenting as hypercalcemic crisis and aplastic anemia: a case report
  3622. The curious case of dermal fibroblasts: cell identity loss may be a mechanism underlying cardiovascular aging
  3623. Drugs that target aging: how do we discover them?
  3624. Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation
  3625. PML bodies in mitosis
  3626. Genomic and Epigenomic Potential With Age: Genome, Epigenome, and the Epigenetic Clock
  3627. Allostatic load and ageing: linking the microbiome and nutrition with age-related health
  3628. Hair of the dog: identification of a cis-regulatory module predicted to influence canine coat composition
  3629. Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis
  3630. Basic and translational aging research in China: present and future
  3631. Healthy aging: a bibliometric analysis of the literature
  3632. The role of pathological aging in cardiac and pulmonary fibrosis
  3633. Transcriptional and epigenetic mechanisms controlling intestinal cell fate
  3634. Restoring the regenerative balance in neuromuscular disorders: satellite cell activation as therapeutic target in Pompe disease
  3635. Vitamin D in physiological and pathological aging: Lesson from centenarians
  3636. The role of DNA repair in cellular aging process
  3637. EMT regulation by autophagy: a new perspective in glioblastoma biology
  3638. The role of CXCR4 in multiple myeloma: Cells’ journey from bone marrow to beyond
  3639. Mononuclear cell telomere attrition is associated with overall survival after nonmyeloablative allogeneic hematopoietic cell transplantation for hematologic …
  3640. Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance
  3641. Divide or commit–revisiting the role of cell cycle regulators in adult hippocampal neurogenesis
  3642. The molecular clock in the skin, its functionality, and how it is disrupted in cutaneous melanoma: a new pharmacological target?
  3643. The cGAS/STING pathway: a sensor of senescence-associated DNA damage and trigger of inflammation in early age-related macular degeneration
  3644. The microbiome and aging
  3645. Molecular pathways mediating immunosuppression in response to prolonged intensive physical training, low-energy availability, and intensive weight loss
  3646. Time for the syStems-level integration of aging: resilience enhancing strategies to prevent Alzheimer’s disease
  3647. Time for a new strategy in the war on Alzheimer’s disease
  3648. Rejuvenation of Aged Heart Explant-Derived Cells for Repair of Ischemic Cardiomyopathy
  3649. Cellular senescence in bone
  3650. Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
  3651. TRANSLATIONAL REVIEW
  3652. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
  3653. cell kinetics in the adult neurogenic niche and impact of diet-induced accelerated aging
  3654. Serum CXCL2 Level Can Predict High-Fat Diet-Induced Impairment of Bone Marrow Mesenchymal Stem Cells
  3655. Altered myogenesis and premature senescence underlie human TRIM32-related myopathy
  3656. A role for CXC chemokines and their receptors in stress axis regulation of common carp
  3657. The mTOR inhibitor everolimus overcomes CXCR4-mediated resistance to histone deacetylase inhibitor panobinostat through inhibition of p21 and mitotic regulators
  3658. Exosome determinants of physiological aging and age-related neurodegenerative diseases
  3659. A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress
  3660. Mathematical model to study the aging of the human follicle according to the telomerase activity
  3661. Toward understanding genomic instability, mitochondrial dysfunction and aging
  3662. Nuclear organization in stress and aging
  3663. Approaches towards longevity: reprogramming, senolysis, and improved mitotic competence as anti-aging therapies
  3664. Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
  3665. Epigenetic clock analysis of blood samples from Japanese schizophrenia patients
  3666. Lung function trajectories in health and disease
  3667. CDK7 inhibition as a promising therapeutic strategy for lung squamous cell carcinomas with a SOX2 amplification
  3668. A concise review of human brain methylome during aging and neurodegenerative diseases
  3669. FOXO3 on the road to longevity: lessons from SNPs and chromatin hubs
  3670. A new member of the runt domain family from Pacific oyster Crassostrea gigas (CgRunx) potentially involved in immune response and larvae hematopoiesis
  3671. Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML
  3672. Evolving insights into the cellular and molecular pathogenesis of fibrosis in syStemic sclerosis
  3673. Metabolism-based therapeutic strategies targeting cancer Stem cells
  3674. A defined human aging phenome
  3675. Measuring gait speed to better identify prodromal dementia
  3676. The global clonal complexity of the murine blood syStem declines throughout life and after serial transplantation
  3677. First hint that body’s ‘biological age’can be reversed
  3678. Neuromuscular junction as an entity of nerve-muscle communication
  3679. Developments in molecular epidemiology of aging
  3680. Differential expression of phospho‐S6 in hair follicle tumors: Evidence of mammalian target of rapamycin pathway activation
  3681. A regulatory pathway for medicines that target aging
  3682. MicroRNAs and the genetic nexus of brain aging, neuroinflammation, neurodegeneration, and brain trauma
  3683. Are we ill because we age?
  3684. Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey
  3685. Putative Role of Nuclear Factor-Kappa B But Not Hypoxia-Inducible Factor-1a in Hypoxia-Dependent Regulation of Oxidative Stress in Hematopoietic Stem and …
  3686. What Is the Exposome and How It Can Help Research on Air Pollution
  3687. Chaperones and their role in telomerase ribonucleoprotein biogenesis and telomere maintenance
  3688. Classical monocytes from older adults maintain capacity for metabolic compensation during glucose deprivation and lipopolysaccharide stimulation
  3689. Gene network analysis of senescence-associated genes in annual plants and comparative assessment of aging in perennials and animals
  3690. Mechanisms and therapeutic prospects of thrombopoietin receptor agonists
  3691. Age-related gene and miRNA expression changes in airways of healthy individuals
  3692. The genomic health of human pluripotent Stem cells: genomic instability and the consequences on nuclear organization
  3693. Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling
  3694. Telomere-related gene mutations and lung diseases: Pulmonary fibrosis, emphysema and lung cancer
  3695. Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors
  3696. Comparative proteome-wide analysis of bone marrow microenvironment of β-thalassemia/hemoglobin E
  3697. Ageing and cognition
  3698. Revamping the evolutionary theories of aging
  3699. Dementia: Module 2
  3700. Cdk7: a kinase at the core of transcription and in the crosshairs of cancer drug discovery
  3701. Structural analysis and conformational dynamics of STN1 gene mutations involved in coat plus syndrome
  3702. Integrating functional ageing into daily clinical practice
  3703. Telomere abnormalities in the pathobiology of idiopathic pulmonary fibrosis
  3704. The Maintaining and Directed Differentiation of Hematopoietic Stem Cells Under Microgravity
  3705. Psychological wellbeing and healthy aging: focus on telomeres
  3706. Improving health in later life: how a life course approach could improve health and well-being in old Age
  3707. NAD+ in brain aging and neurodegenerative disorders
  3708. The Purification of Human Adult Progenitor cell Types to Promote Angiogenesis
  3709. Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates
  3710. Dynamic reciprocity: the role of the extracellular matrix microenvironment in amplifying and sustaining pathological lung fibrosis
  3711. Telomere dynamics in children undergoing cancer treatment and the relationship between telomere length and treatment outcome
  3712. Aging of immune syStem
  3713. Identification of Chromatin Regulators Perturbed in Hematopoietic Stem and Progenitor cell Aging
  3714. Hydroxytyrosol prevents dermal papilla cells inflammation under oxidative stress by inducing autophagy
  3715. Inferring immunological control mechanisms from TKI dose alterations in CML patients
  3716. A Nontarget Mechanism to Explain Carcinogenesis Following α-Irradiation
  3717. The effect of exclusive olive oil consumption on successful aging: a combined analysis of the ATTICA and MEDIS epidemiological studies
  3718. Characterization of LINC Complex-mediated Regulation of Satellite Stem and Progenitor cell Cycles
  3719. Let-7 miRNA’s expression profile and its potential prognostic role in uterine leiomyosarcoma
  3720. Investigating nutrient-sensing pathways in ageing human neural Stem cells and age-related cognitive decline
  3721. The epidemiology of frailty and its association with disability and quality of life among rural community-dwelling older adults in Kegalle district of Sri Lanka
  3722. Skeletal muscle Stem cells
  3723. What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?
  3724. Somatic mutations in healthy cells and age-associated diseases
  3725. Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis
  3726. An inflammatory clock predicts multi-morbidity, immunosenescence and cardiovascular aging in humans
  3727. Histological and Immunohistochemical Study of Selenium Regenerative Effect on Submandibular and Sublingual Glands of Aging Rats
  3728. Trade-offs between mortality components in life history evolution: the case of cancers
  3729. Circular RNA expression profile in human fibroblast premature senescence after repeated ultraviolet B irradiations revealed by microarray
  3730. Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair
  3731. Infections in elderly intensive care unit patients
  3732. The Human Lung cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease
  3733. The role of E3 ubiquitin ligase FBXO9 in normal and malignant hematopoiesis
  3734. Mitophagy, Diseases, and Aging
  3735. NADPH oxidases and aging models of lung fibrosis
  3736. Metformin Modulates the Mechanisms of Ageing
  3737. Keratin 19 regulates cell cycle pathway and sensitivity of breast cancer cells to CDK inhibitors
  3738. Metabolic Stress—Signaling and Metabolic Adaptation
  3739. Role and Perspective of Sport Science in Health Promotion and Elite Sport
  3740. Caveolin-1 as a critical component in the pathogenesis of lung fibrosis of different etiology: Evidences and mechanisms
  3741. Molecular Signature of Aging Driven by Wnt Signaling Pathway: Lessons from Nematodes
  3742. ZEB1 protects skeletal muscle from damage and is required for its regeneration
  3743. The Origins of Ageing
  3744. Identifying potential ageing-modulating drugs in silico
  3745. The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis
  3746. Monocytes from Older Adults Maintain Capacity for Metabolic Compensation during Glucose Deprivation and Lipopolysaccharide Stimulation
  3747. The role of epigenetic aging in education and racial/ethnic mortality disparities among older US Women
  3748. Genetic pathways of aging and their relevance in the dog as a natural model of human aging
  3749. Chromosomal instability and pro-inflammatory response in aging
  3750. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis
  3751. Premature aging syndromes: From patients to mechanism
  3752. Quality of life in idiopathic pulmonary fibrosis: The impact of sleep disordered breathing
  3753. Extraribosomal Regulation of Myeloid Leukemogenesis by Rpl22
  3754. Differential gene expression changes and their implication on the disease progression in patients with chronic myeloid leukemia
  3755. Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy
  3756. Studies on the effect of Time-Restricted Feeding on ageing and carcinogenesis
  3757. The response to DNA damage at telomeric repeats and its consequences for telomere function
  3758. Bioactive compounds as therapeutic alternatives
  3759. The Cambridge handbook of successful aging
  3760. PHYTOCHEMICALS AS PROSPECTIVE HUMAN ANTI-AGING COMPOUNDS
  3761. Nuclear Organization in Stress and Aging
  3762. Emerging roles of sestrins in neurodegenerative diseases: counteracting oxidative stress and beyond
  3763. Histone modifications as an intersection between diet and longevity
  3764. Targeting chronic innate inflammatory pathways, the main road to prevention of osteoarthritis progression
  3765. Calcium mechanisms in limb-girdle muscular dystrophy with CAPN3 mutations
  3766. Molecular Insights into Hutchinson-Gilford Progeria Syndrome and Age-associated Disease: From Mechanisms to Treatment Strategy
  3767. Therapeutic targeting of transcriptional cyclin-dependent kinases
  3768. Stammzellen und Akne Cellules souches et acné
  3769. Epigenetics and ageing
  3770. Targeting mitochondrial bioenergetics and NAD+ metabolism during sarcopenia and regeneration of skeletal muscle
  3771. Ginger (Zingiber officinale Roscoe) in the prevention of ageing and degenerative diseases: review of current evidence
  3772. Variable DNA methylation of aging-related genes is associated with male COPD
  3773. Leveraging budding yeast Saccharomyces cerevisiae for discovering aging modulation substances for functional food
  3774. Plant-rich dietary patterns, plant foods and nutrients, and telomere length
  3775. Revisiting successful aging with HIV through a revised biopsychosocial model: An update of the literature
  3776. Epigenetic aging is associated with clinical and experimental pain in community-dwelling older adults
  3777. Negative conditioning of mitochondrial dysfunction in age-related neurodegenerative diseases
  3778. What can yeast tell us about aging modulation by bioactive substances in functional food
  3779. 11 Genetic Syndromes and Aging
  3780. The cryo-EM structure of human CST reveals a two-megadalton decameric assembly bound to telomeric DNA
  3781. Lifespan: Why we age—And why we Don’t have to
  3782. Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes
  3783. Down syndrome, ageing and epigenetics
  3784. Transient Reprogramming for Multifaceted Reversal of Aging Phenotypes
  3785. Two stochastic processes shape diverse senescence patterns in a single‐cell organism
  3786. Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study
  3787. Genetic Syndromes and Aging
  3788. Adipogenesis of skeletal muscle Fibro/Adipogenic Progenitors is controlled by the WNT5a/GSK3/β-catenin axis
  3789. Determinants and prevention of coronary disease in patients with chronic kidney disease
  3790. G protein-coupled receptor syStems and their role in cellular senescence
  3791. Total energy expenditure measured using doubly labeled water compared with estimated energy requirements in older adults (≥ 65 y): analysis of primary data
  3792. The metabolomics side of frailty: Toward personalized medicine for the aged
  3793. The vivo antioxidant activity of self-made aged garlic extract on the d-galactose-induced mice and its mechanism research via gene chip analysis
  3794. Current state of saliva biomarkers for aging and Alzheimer’s disease
  3795. Immunohistochemistry and molecular biology in transbronchial cryobiopsies
  3796. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells
  3797. Early induction of C/EBPβ expression as a potential marker of steroid responsive colitis
  3798. and Venerino Poletti
  3799. Cataractogenic load–A concept to study the contribution of ionizing radiation to accelerated aging in the eye lens
  3800. Role of obesity in the development of acute promyelocytic leukemia (APL)
  3801. Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age
  3802. The microbiota-gut-brain axis
  3803. Role of combined lipoic acid and vitamin D3 on astrocytes as a way to prevent brain ageing by induced oxidative stress and iron accumulation
  3804. Slowing down ageing: the role of nutrients and microbiota in modulation of the epigenome
  3805. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association
  3806. Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip
  3807. Effects of aging and diet on cardioprotection and cardiometabolic risk markers
  3808. Hydrogen Sulfide Improves Aberrant Gastric Smooth Muscle Function in Duchenne Muscular Dysrophy Mice
  3809. Metabolism of sleep and aging: Bridging the gap using metabolomics
  3810. Is Nature our Best Assurance of Healthy Ageing? Lessons from age-resilient animal species
  3811. Functional characterization and clinical relevance of ubiquitin conjugating enzyme E2T in hepatocellular carcinoma
  3812. Oxidative stress induces telomere dysfunction and senescence by replication fork arrest
  3813. DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis
  3814. Identifying Rare Somatic Mutations as a Means of Understanding Tissue Clonal Evolution
  3815. Stem Cells: From Myth to Reality and Evolving
  3816. Bone-resident mesenchymal stromal cells in healthy ageing and osteoarthritis: enumeration and gene expression analysis in uncultured cells
  3817. The role of arginase in aging: a syStematic review
  3818. Chance and causality in ageing and Longevity
  3819. Rational particle design to overcome pulmonary barriers for obstructive lung diseases therapy
  3820. The role of Stem cells in development of heart failure associated with Duchenne muscular dystrophy
  3821. Prophylaxis of non-communicable diseases: why fruits and vegetables may be better chemopreventive agents than dietary supplements based on isolated …
  3822. The role of lipid metabolism in aging, lifespan regulation, and age‐related disease
  3823. Conditioning Medicine
  3824. Handgrip strength and pulmonary disease in the elderly: what is the link?
  3825. Relationships between ion channels, mitochondrial functions and inflammation in human aging
  3826. Implication of the receptor for advanced glycation end-products (RAGE) during inflammation and ageing
  3827. DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications
  3828. States and Fates of Primitive Neural Stem Cells and Their Progeny in the Mammalian Brain
  3829. Caloric restriction and the nutrient-sensing protein kinase TOR1 alter the pattern of protein phosphorylation in quiescent and non-quiescent cells of Saccharomyces …
  3830. Brain region-specific effects of long-term caloric restriction on redox balance of the aging rat
  3831. Mechanisms of heat-induced lifespan extension in Saccharomyces cerevisiae and Caenorhabditis elegans
  3832. Redox imbalance in idiopathic pulmonary fibrosis: a role for oxidant cross-talk between NADPH oxidase enzymes and mitochondria
  3833. The Role of mtDNA Mutation and Mitochondrial Dysfunction on the Aging Process
  3834. Conserved signaling pathways genetically associated with longevity across the species
  3835. Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach
  3836. Análisis genómico y funcional de las células madre mesenquimales de médula ósea de pacientes osteoporóticos
  3837. Better options for best clinical practice
  3838. Mitochondria in the signaling pathways that control longevity and health span
  3839. TFIIH: A multi-subunit complex at the cross-roads of transcription and DNA repair
  3840. Marmosets in aging research
  3841. Vesicles and microRNAs of the senescence-associated-secretory-phenotype: An evaluation of their anti-apoptotic effect on dermal fibroblasts
  3842. Metabolic Flexibility in Classical Monocytes is not Affected by Age
  3843. Xiaqing Zhao and Daniel EL Promislow
  3844. Agephagy–Adapting autophagy for health during aging
  3845. LAMINOPATHIES: PATHOLOGY, cell MECHANICS ANDENVIRONMENTAL INDUCTION.
  3846. Pharmacological Management of Chronic Obstructive Lung Disease (COPD). Focus on Mutations-Part 1
  3847. Mitotic chromosome alignment ensures mitotic fidelity by promoting interchromosomal compaction during anaphase
  3848. Rare Cells Play Central Roles in Airway Maintenance
  3849. Osteopontin role in lipid metabolism: involvement in age-related hepatosteatosis
  3850. How does allostatic load relate to cognitive ability, depressive symptoms and other measures of physiological weathering in older age?
  3851. Ssu72 phosphatase is a conserved telomere replication terminator
  3852. Linker histones and chromatin remodelling complexes maintain genome stability and control cellular ageing
  3853. Frailty syndrome and cognitive impairment in older adults: syStematic review of the literature
  3854. On the epigenetic ageing clock in humans
  3855. Praise for LIFESPAN
  3856. Circadian Oscillations of the Mouse and Human Epigenome
  3857. Circadian Oscillations of the Mouse and Human Epigenome
  3858. Antagonism of the Thromboxane‐Prostanoid Receptor as a Potential Therapy for Cardiomyopathy of Muscular Dystrophy
  3859. Clinical and Preclinical Application of Magnetic Resonance Spectroscopy in Aging and Amyotrophic Lateral Sclerosis
  3860. DNA methylation changes during aging and in age-associated diseases
  3861. Probing the impact of the maternal environment on foetal development: Can high-resolution telomere analysis predict prenatal adversity?
  3862. RECQL4; Linking DNA Replication and Bone Tumourigenesis
  3863. Human CST complex protects replication fork stability by directly blocking MRE11 degradation of nascent strand DNA
  3864. Towards a unified mechanistic theory of aging
  3865. Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules
  3866. Oxidative Stress-Induced Autophagy Impairment and Pathogenesis
  3867. The Biology of Senescence
  3868. DNA methylation patterns in aging and aging phenotypes
  3869. Oxidative Stress-Induced Autophagy Impairment and Pathogenesis of Chronic Obstructive Lung Diseases
  3870. Geriatric Anesthesia
  3871. Difficult to Diagnose Rare Diffuse Lung Disease
  3872. Cellular calcium signaling in the aging brain
  3873. Mitophagy and oxidation status of mitochondria in Idiopathic Pulmonary Fibrosis (IPF) macrophages: a study in bronchoalveolar lavage fluid (BALF)
  3874. Mammalian CST averts replication failure by preventing G-quadruplex accumulation
  3875. Age-and tumor-dependent senescence in canine testis and eye
  3876. Identifying MicroRNAs Responsible for the Opposite Longevity Roles of Caenorhabditis elegans Argonautes
  3877. Investigating Telomere Length Dynamics In Human Endothelial Cells
  3878. Intrarenal Renin–Angiotensin SyStem Involvement in the Pathogenesis of Chronic Progressive Nephropathy—Bridging the Informational Gap Between Disciplines
  3879. GFI1B Regulation and Transcriptional Repression Depend on Its Interacting Partners
  3880. The Use of the Drosophila Genetic Reference Panel to Map Genes Underlying High Fat Diet-induced Mortality
  3881. High-Throughput Chronological Lifespan Screening of the Fission Yeast Deletion Library Using Barcode Sequencing
  3882. TRF1 prevents permissive DNA damage response, recombination and Break Induced Replication at telomeres
  3883. The delta opioid receptor influences circadian rhythms in human N/TERT‑1 keratinocytes through the β‑arrestin pathway
  3884. Jump Start Autophagy: Activate Your Body’s Cellular Healing Process to Reduce Inflammation, Fight Chronic Illness and Live a Longer, Healthier Life
  3885. Glucose Availability Impacts Proteotoxic Stress in Caenorhabditis Elegans
  3886. A mitochondrial approach to cardiovascular risk and disease
  3887. Epigenetics and pharmacoepigenetics of age-related neurodegenerative disorders
  3888. Analysis of CDK2 Function During Meiosis
  3889. Development of dystrophin-based biomarker for penaeid shrimps/Raji Fatimah Omotayo
  3890. Pro-Senescence Therapy by Targeting MYC and Its Network as a Strategy to Combat Cancer
  3891. Targeting cell Intrinsic and Extrinsic Mechanisms Involved in the Initiation and Maintenance of Non-Small cell Lung Cancer
  3892. Role of Antioxidants in the Protection from Aging-Related Diseases
  3893. Discovering and Targeting the Mechanisms that Govern Age-Related Decline
  3894. Mechanisms of fibrosis in IPF
  3895. Impact of cardiovascular and neuropsychiatric multimorbidity on older adults’ health
  3896. Identification of DDX1 as a novel interactor of CDK-Activating Kinase and its implication in Trichothiodystrophy disorder
  3897. Mind-Body Wellness Program Benefits
  3898. Explaining infertility: a Sperm DNA Fragmentation review
  3899. Retrotransposition and Ageing-associated Neuronal Function Decline
  3900. Intrinsically Disorder Proteins and Liquid-Liquid Phase Transitions in Neurodegenerative Diseases
  3901. Reverse Engineering of Natural SyStems by Graph Theory
  3902. Fasting-mimicking diet-based non-toxic combination therapy in cancer treatment: from molecules to bedside
  3903. Long Live The Queen: influence of membrane phospholipids on longevity of honey bees
  3904. Study of Epigenetic Signatures Associated with Neuronal Differentiation, Aging and Alzheimer’s Disease
  3905. Imaging of Interstitial Lung Diseases
  3906. Correlating the prevalence of C174G polymorphism with IL-6, TNF-α and Hs-CRP in an elderly black South African population.
  3907. Demographics and Telomere Dynamics of Hibernating Arctic Ground Squirrels (Urocitellus parryii)
  3908. Transforming the future of ageing: informs the forthcoming Scientific Opinion of the European Commission Group of Chief Scientific Advisors
  3909. Age-related changes of glutathione homeostasis in Caenorhabditis elegans
  3910. The mitochondrial ageing signature; seeing the light
  3911. Novel Insights into the Molecular Mechanisms that Control Stress Responses in Senescent Cells
  3912. The role of the C. elegans Aryl hydrocarbon receptor in environmentally-driven aging
  3913. Design and Implementation of A Fully Reconstituted Assay To Investigate Mechanisms of Early Human Pol II Transcription
  3914. TGF-β mediated synthesis of degradation-resistant collagen (I) homotrimer in musculoskeletal cells
  3915. A Neuronal G Protein-coupled Receptor Mediates the Effect of Diet on Lifespan and Development in Caenorhabditis elegans Through Autophagy
  3916. Hes1 deficiency causes hematopoietic Stem cell exhaustion
  3917. The mitochondria regulation of Stem cell aging
  3918. ATF3 Prevents Stress-Induced Hematopoietic Stem cell exhaustion
  3919. Emerging role of Stem cell -derived extracellular microRNAs in age-associated human diseases and in different therapies of longevity
  3920. Combined antioxidant, anti-inflammaging and mesenchymal Stem cell treatment: a possible therapeutic direction in elderly patients with chronic obstructive …
  3921. Arabidopsis Casein Kinase 2 triggers Stem cell exhaustion under Al Toxicity and Phosphate Deficiency Through activation of the DNA Damage Response pathway
  3922. Senescent Mesenchymal Stem Cells: Disease Mechanism and Treatment Strategy
  3923. Small molecules restore telomeres in patient Stem cells
  3924. Protection of hematopoietic Stem cells from stress-induced exhaustion and aging
  3925. Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle Stem cell pool
  3926. Small-molecule PAPD5 inhibitors restore telomerase activity in patient Stem cells
  3927. Comprehensive analysis of skeletal muscle-and bone-derived mesenchymal Stem/stromal cells in patients with osteoarthritis and femoral neck fracture
  3928. The role of the Stem cell epigenome in normal aging and rejuvenative therapy
  3929. Stem Cells and Aging
  3930. Stem cell aging in lifespan and disease: A state-of-the-art review
  3931. Human basal cell carcinoma: the induction of anagen hair follicle differentiation
  3932. Substance P aggravates corneal epithelial Stem cell deficiency
  3933. Extracellular vesicles from healthy cells improves cell function and Stemness in premature senescent Stem cells by miR-302b and HIF-1α activation
  3934. Distal lung epithelial progenitor cell function declines with age
  3935. Sestrins regulate age-induced deterioration of muscle Stem cell homeostasis
  3936. Stem cell DNA damage and genome mutation in the context of aging and cancer initiation
  3937. Of mesenchymal Stem/stromal cells and osteoarthritis: time to merge the latest breakthroughs
  3938. Elevated p38MAPK activity promotes neural Stem cell aging
  3939. Pluripotent Stem cell -based cell therapy—promise and challenges
  3940. Ttc7a regulates hematopoietic Stem cell functions while controlling the stress-induced response
  3941. Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal Stem cells
  3942. Vitamin D receptor controls cell Stemness in acute myeloid leukemia and in normal bone marrow
  3943. Increased exhaustion of the subchondral bone-derived mesenchymal Stem/stromal cells in primary versus dysplastic osteoarthritis
  3944. Hair follicle differentiation‐specific keratin expression in human basal cell carcinoma
  3945. Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic Stem cell populations
  3946. The dual role of ROS in hematological malignancies: Stem cell protection and cancer cell metastasis
  3947. How cancer therapeutics cause accelerated aging: Insights from the hallmarks of aging
  3948. Functional changes in decidual mesenchymal Stem/stromal cells are associated with spontaneous onset of labour
  3949. Treating osteoarthritis via gene therapy with rejuvenation factors
  3950. Metabolic regulation and related molecular mechanisms in various Stem cell functions
  3951. Humanized zebrafish enhance human hematopoietic Stem cell survival and promote acute myeloid leukemia clonal diversity
  3952. Rapamycin for aging Stem cells
  3953. Hematopoietic Stem cell metabolism during development and aging
  3954. Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells
  3955. Hematopoietic Stem cell regulation by the proteostasis network
  3956. Reducing hypothalamic Stem cell senescence protects against aging-associated physiological decline
  3957. Somatic selection of poorly differentiating variant Stem cell clones could be a key to human ageing
  3958. Targeting aging pathways in chronic obstructive pulmonary disease
  3959. ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells
  3960. Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on Stem cell and organismal aging
  3961. Lipid mediated regulation of adult Stem cell behavior
  3962. Dietary Restriction Delays But Cannot Heal Irradiation-Induced Hair Graying by Preserving Hair Follicle Stem Cells in Quiescence
  3963. Stem cell ageing of the root apical meriStem of Arabidopsis thaliana
  3964. IPA Software Analysis Reveals Inflammation and Apoptosis as Major Enrichment Functional Process in Normal Lung During Aging
  3965. Introductions to the community: Early-career researchers in the time of COVID-19
  3966. MTORC1 and the Rebirth of Stemness
  3967. Metabolic dysfunction in Hutchinson–Gilford progeria syndrome
  3968. Treating osteoarthritis via gene therapy with rejuvenation factors
  3969. Exercise protects proliferative muscle satellite cells against exhaustion via the Igfbp7-Akt-mTOR axis
  3970. Stem cell aging in skeletal muscle regeneration and disease
  3971. Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the Stem cell -derived airway repair response
  3972. The role of metabolic plasticity in blood and brain Stem cell pathophysiology
  3973. The aging skin microenvironment dictates Stem cell behavior
  3974. Aging and rejuvenation of neural Stem cells and their niches
  3975. The intrinsic proteostasis network of Stem cells
  3976. Application of the Frameworks of Intrinsic Capacity and the Hallmarks of Aging to Validate Nicotinamide Riboside as a Healthy Aging Supplement–A Meta-Analysis
  3977. Deregulated mito-nuclear communication alters chromatin plasticity and differentiation potential of mesenchymal Stem cells upon ageing
  3978. Mesenchymal Stem cell derived extracellular vesicles in aging
  3979. Of mice, genes and aging
  3980. FOXO activity adaptation safeguards the hematopoietic Stem cell compartment in hyperglycemia
  3981. Glutamine metabolism controls Stem cell fate reversibility and long-term maintenance in the hair follicle
  3982. Loss of Tissue Regenerative Ca-pacity in Aging-The Tendon
  3983. Boosting mitochondrial biogenesis for healthy ageing
  3984. Ageing, metabolism and the intestine
  3985. Ageing in human parturition: impetus of the gestation clock in the decidua
  3986. Benefits of metformin in attenuating the hallmarks of aging
  3987. Notch signaling mitigates chemotherapy toxicity by accelerating hematopoietic Stem cells proliferation via c-Myc
  3988. Aging of the ventricular-subventricular zone neural Stem cell niche
  3989. MicroRNAs in hematopoietic Stem cell aging
  3990. How Could We Slow or Reverse the Human Aging Process and Extend the Healthy Life Span with Heterochronous Autologous Hematopoietic Stem cell …
  3991. Signal transduction in the early Drosophila follicle Stem cell lineage
  3992. DNA repair fidelity in Stem cell maintenance, health, and disease
  3993. Neuroimmune/hematopoietic axis with distinct regulation by the high-mobility group box 1 in association with tachykinin peptides
  3994. Extracellular serine controls epidermal Stem cell fate and tumour initiation
  3995. The eroding chromatin landscape of aging Stem cells
  3996. FoxO maintains a genuine muscle Stem–cell quiescent state until geriatric age
  3997. Epigenetic clock: DNA methylation in aging
  3998. Ganoderic acid D protects human amniotic mesenchymal Stem cells against oxidative stress-induced senescence through the PERK/NRF2 signaling pathway
  3999. Restoring aged Stem cell functionality: Current progress and future directions
  4000. Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging
  4001. Mechanisms and rejuvenation strategies for aged hematopoietic Stem cells
  4002. C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic Stem cells
  4003. Are trade‐offs really the key drivers of ageing and life span?
  4004. Adipose stromal cell expansion and exhaustion : Mechanisms and consequences
  4005. Expression levels of SMAD specific E3 ubiquitin protein ligase 2 (Smurf2) and its interacting partners show region-specific alterations during brain aging
  4006. A novel tissue culture model for evaluating the effect of aging on Stem cell fate in adult microvascular networks
  4007. Attenuated regenerative properties in human periodontal ligament–derived Stem cells of older donor ages with shorter telomere length and lower SSEA4 expression
  4008. Dietary phytochemical approaches to Stem cell regulation
  4009. Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells
  4010. Modification of Stem cell states by alcohol and acetaldehyde
  4011. GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic Stem cells
  4012. Targeting cardiac Stem cell senescence to treat cardiac aging and disease
  4013. Hypercholesterolemia accelerates the aging phenotypes of hematopoietic Stem cells by a Tet1-dependent pathway
  4014. Aging-related reduced expression of CXCR4 on bone marrow mesenchymal stromal cells contributes to hematopoietic Stem and progenitor cell defects
  4015. Revisiting the hallmarks of aging to identify markers of biological age
  4016. Stem cells and lung regeneration
  4017. The landscape of GPCR signaling in the regulation of epidermal Stem cell fate and skin homeostasis
  4018. The changing epigenetic landscape of mesenchymal Stem/stromal cells during aging
  4019. TICAM2-related pathway mediates neutrophil exhaustion
  4020. Measuring biological aging in humans: A quest
  4021. Prolonged hypoxia delays aging and preserves functionality of human amniotic fluid Stem cells
  4022. Hallmarks of aging Drosophila intestinal Stem cells
  4023. Notch dimerization and gene dosage are important for normal heart development, intestinal Stem cell maintenance, and splenic marginal zone B-cell …
  4024. Senescence in pulmonary fibrosis: between aging and exposure
  4025. PI3K in Stemness regulation: From development to cancer
  4026. Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells
  4027. Organoid models in lung regeneration and cancer
  4028. Therapeutic strategies targeting somatic Stem cells: Chemical approaches
  4029. Tet1 deficiency leads to premature reproductive aging by reducing spermatogonia Stem cells and germ cell differentiation
  4030. Progressive changes in hippocampal Stem cell properties ensure lifelong neurogenesis
  4031. Persistent DNA damage–induced NLRP12 improves hematopoietic Stem cell function
  4032. Novel Therapeutics for Bone Marrow Failure Disorders Due to Telomere exhaustion
  4033. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
  4034. Cellular senescence: A pathogenic mechanism of pelvic organ prolapse
  4035. Mouth-watering results: clinical need, current approaches, and future directions for salivary gland regeneration
  4036. Targeting the aryl hydrocarbon receptor in Stem cells to improve the use of food as medicine
  4037. Aging skin and non-surgical procedures: a basic science overview
  4038. The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells
  4039. AQP5 regulates the proliferation and differentiation of epidermal Stem cells in skin aging
  4040. Mechanoregulation in hematopoiesis and hematologic disorders
  4041. Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation
  4042. mTOR signaling at the crossroad between metazoan regeneration and human diseases
  4043. Type I interferons and related pathways in cell senescence
  4044. Adult neurogenesis and the molecular signalling pathways in brain: The role of Stem cells in adult hippocampal neurogenesis
  4045. EphA7+ perivascular cells as myogenic and angiogenic precursors improving skeletal muscle regeneration in a muscular dystrophic mouse model
  4046. Does clonal hematopoiesis explain unexplained anemia?
  4047. Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle Stem cell fate
  4048. Its written all over your face: The molecular and physiological consequences of aging skin
  4049. Retention of somatic memory associated with cell identity, age and metabolism in induced pluripotent Stem (iPS) cells reprogramming
  4050. CXCR4s in teleosts: two paralogous chemokine receptors and their roles in hematopoietic Stem/progenitor cell homeostasis
  4051. Lack of PKCθ promotes regenerative ability of muscle Stem cells in chronic muscle injury
  4052. Eltrombopag treatment promotes platelet recovery and reduces platelet transfusion for patients with post-transplantation thrombocytopenia
  4053. Nutrient sensing, the oxidative stress response, and Stem cell aging
  4054. FOOTNOTES
  4055. Anti-aging effects of Ribes meyeri anthocyanins on neural Stem cells and aging mice
  4056. Regulation of Stress Induced Hematopoiesis
  4057. New insights into the basic biology of acute graft-versus-host-disease
  4058. Dissecting Clonal Heterogeneity in AML
  4059. cell polarity in hematopoietic Stem cell quiescence, signaling and fate determination
  4060. The ageing epigenome and its rejuvenation
  4061. Exposure to mites sensitizes intestinal Stem cell maintenance, splenic marginal zone B cell homeostasis, and heart development to notch dosage and cooperativity
  4062. Sex hormone replacement therapy in periodontology—A syStematic review
  4063. Focus: Sex & Reproduction: Impact of Ovarian Aging in Reproduction: From Telomeres and Mice Models to Ovarian Rejuvenation
  4064. The Powerful Roles of Nad+ in Anti-Aging
  4065. Skeletal Muscle Stem cell Niche from Birth to Old Age
  4066. ITGB1 promotes the chondrogenic differentiation of human adipose-derived mesenchymal Stem cells by activating the ERK signaling
  4067. Effects of pre-and/or postnatal smoke exposure on the hallmarks of the ageing phenotype and the role for the IGF1 pathway
  4068. TSC1 regulates the proliferation capacity of bone-marrow derived mesenchymal Stem cells
  4069. CXCR4 expression in the bone marrow microenvironment is required for hematopoietic Stem and progenitor cell maintenance and early hematopoietic regeneration …
  4070. Senescence and longevity of sea urchins
  4071. Understanding “LONGEVITY” at Molecular Level. A Comprehensive Review.
  4072. Metabolic syndrome impairs 3D mitochondrial structure, dynamics, and function in swine mesenchymal Stem cells
  4073. Frailty and aging in cancer survivors
  4074. SOX2 in development and cancer biology
  4075. Neuroinflammation and oxidative stress in the aging brain: Linking in metabolism, Stem cells, proteostasis, and stress adaptation
  4076. Role of cell Cycle Control, Checkpoints, and DNA Repair Mechanisms in Stem Cells and Changes with Aging and Cancerogenesis
  4077. Gerobiotics: probiotics targeting fundamental aging processes
  4078. Global dynamics of healthy and cancer cells competing in the hematopoietic syStem
  4079. Regulation of Stem Cells by Cullin-RING Ligase
  4080. Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis
  4081. Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts
  4082. EZH2 function in immune cell development
  4083. Biomarkers of cognitive impairment in late-life depression
  4084. Driver mutations in leukemia promote disease pathogenesis through a combination of cell -autonomous and niche modulation
  4085. Culture nTAD: A New Avenue for Research in Late-stage Human Lung Development and Perinatal Lung Disease
  4086. Decrease of laminin-511 in the basement membrane due to photoaging reduces epidermal Stem/progenitor cells
  4087. Comparison of chronic myeloid leukemia Stem cells and hematopoietic Stem cells by global proteomic analysis
  4088. Integrating the hallmarks of aging throughout the tree of life: a focus on mitochondrial dysfunction
  4089. Redox regulation of regulatory T-cell differentiation and functions
  4090. Crosstalk between autophagy and metabolic regulation of cancer Stem cells
  4091. Targeting PPAR ligands as possible approaches for metabolic reprogramming of T cells in cancer immunotherapy
  4092. Lifestyle mediates the role of nutrient-sensing pathways in cognitive aging: cellular and epidemiological evidence
  4093. Regulation of the bone marrow niche by inflammation
  4094. Dystrophin Dp71ab is monoclonally expressed in human satellite cells and enhances proliferation of myoblast cells
  4095. Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal Stem cells through the aryl hydrocarbon receptor pathway
  4096. Memory of divisional history directs the continuous process of primitive hematopoietic lineage commitment
  4097. Mitochondria and ageing with HIV
  4098. Polycomb Repressive Complex 1 is required to maintain Stem cell identity and to preserve adult tissue homeostasis.
  4099. Chromatin Disorganization as a Regulator of Irradiation-Induced L1Md Expression and Hematopoietic Stem cell Function
  4100. Switching of vascular cells towards atherogenesis, and other factors contributing to atherosclerosis: a syStematic review
  4101. How can aging be reversed? Exploring rejuvenation from a damage‐based perspective
  4102. Transglutaminase type 2 is involved in the hematopoietic Stem cells homeostasis
  4103. Fabry disease: A new model of premature ageing?
  4104. Sestrin family–the Stem controlling healthy ageing
  4105. Menopausal hyperinsulinism and hypertension–new approach
  4106. Skeletal Muscle Stem Cells
  4107. The untapped potential of reptile biodiversity for understanding how and why animals age
  4108. Effects of Trimethylamine N-Oxide on Mouse Embryonic Stem cell Properties
  4109. mTOR in the aging imune syStem
  4110. Characterising Senescence with High-content Imaging and Convolutional Neural Networks
  4111. Effects of varying levels and differing durations of calorie restriction on cellular and synaptic proteins, as well as the inflammatory state of the female mouse brain
  4112. COVID-19 and crosstalk with the hallmarks of aging
  4113. Molecular connections between circadian clocks and aging
  4114. Bone marrow mesenchymal Stem cells differentiate into intestinal epithelioid cells through the ERK1/2 pathway
  4115. Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
  4116. Silver fir (Abies alba L.) polyphenolic extract shows beneficial influence on chondrogenesis in vitro under normal and inflammatory conditions
  4117. Microglia Phagocytosis Contributes to Neural Stem cell Loss in the Aging Subventricular Zone
  4118. SOX2 and p53 expression control converges in PI3K/AKT signaling with versatile implications for Stemness and cancer
  4119. HNF4 regulates fatty acid oxidation and is required for renewal of intestinal Stem cells in mice
  4120. Molecular Regulation of Satellite cell Fate
  4121. Mesenchymal Stem/stromal cell -derived exosomes for immunomodulatory therapeutics and skin regeneration
  4122. FBW7 mediates senescence and pulmonary fibrosis through telomere uncapping
  4123. Piggybac Transposon-Based Lineage Tracing to Reveal Ependymogenesis
  4124. Deficiency of Crif1 in hair follicle Stem cells retards hair growth cycle in adult mice
  4125. Bone marrow stromal cell therapy improves survival after radiation injury but does not restore endogenous hematopoiesis
  4126. Senescent cells: emerging targets for human aging and age-related diseases
  4127. Satellite cells in ageing: use it or lose it
  4128. Frailty in patients with interstitial lung disease
  4129. Age-associated telomere attrition in adipocyte progenitors predisposes to metabolic disease
  4130. Pathophysiology of premature aging characteristics in Mendelian progeroid disorders
  4131. Derivation and characterization of immortalized human muscle satellite cell clones from muscular dystrophy patients and healthy individuals
  4132. Too much iron: A masked foe for leukemias
  4133. The cGAS-STING pathway in hematopoiesis and its physiopathological significance
  4134. Effect of exercise on telomere length and telomere proteins expression in mdx mice
  4135. Senotherapeutics: targeting senescence in idiopathic pulmonary fibrosis
  4136. Periodontal disease and senescent cells: new players for an old oral health problem?
  4137. Wound induced hair neogenesis–a novel paradigm for studying regeneration and aging
  4138. Aging and leukemic evolution of hematopoietic Stem cells under various stress conditions
  4139. Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas
  4140. The E3 ubiquitin ligase CHIP in normal cell function and in disease conditions
  4141. Contribution of aberrant toll like receptor signaling to the pathogenesis of myelodysplastic syndromes
  4142. Vitamin C Treatment Rescues Prelamin A-Induced Premature Senescence of Subchondral Bone Mesenchymal Stem Cells
  4143. Stem cells of the aging brain
  4144. Single-cell Analysis of Muscle Stem cell Heterogeneity in Tissue Regeneration
  4145. Persistence of drug-resistant leukemic Stem cells and impaired NK cell immunity in CML patients depend on MIR300 antiproliferative and PP2A-activating …
  4146. Hematopoietic Stem Cells and Control of Hematopoiesis
  4147. Chromatin Accessibility Dynamics Underlie a Decline in Neural Stem cell Migratory Ability with Age
  4148. Discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia: when and for whom?
  4149. Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers
  4150. Alveolar epithelial type II cells as drivers of lung fibrosis in idiopathic pulmonary fibrosis
  4151. Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal Stem cells through different molecular targets
  4152. Molecular mechanisms contributing to mesenchymal stromal cell aging
  4153. ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin
  4154. Mechanisms of melanocyte polarity and differentiation: What can we learn from other neuroectoderm-derived lineages?
  4155. Nicotinamide riboside enhances mitochondrial proteostasis and adult neurogenesis through activation of mitochondrial unfolded protein response signaling …
  4156. CD86-based analysis enables observation of bona fide hematopoietic responses
  4157. C/EBPβ isoforms sequentially regulate regenerating mouse hematopoietic Stem/progenitor cells
  4158. 15-PGDH as a Negative Regulator of Age-Related Organ Fitness
  4159. cell and gene therapy for spine regeneration: Mammalian protein production platforms for overproduction of therapeutic proteins and growth factors
  4160. An update on the molecular pillars of aging
  4161. TOR signaling inhibition in intestinal Stem and progenitor cells affects physiology and metabolism in Drosophila
  4162. MMR-proficient and MMR-deficient colorectal cancer cells: 5-Fluorouracil treatment response and correlation to CD133 and MGMT expression
  4163. Elixir of Youth: Lipid Signaling Chaperones Synthesized in the Liver
  4164. The Hippo–YAP Signaling as Guardian in the Pool of Intestinal Stem Cells
  4165. RUNX1 gene mutations are associated with adverse prognosis of patients with acute myeloidleukemia
  4166. Redox signaling in cellular differentiation
  4167. Mitochondrial dynamics and metabolism in induced pluripotency
  4168. Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic Stem cells using a clinically applicable …
  4169. Caloric restriction reprograms the single-cell transcriptional landscape of Rattus norvegicus aging
  4170. Aging and the biological response to liver injury
  4171. Wnts and the hallmarks of cancer
  4172. TIGAR/AP-1 axis accelerates the division of Lgr5− reserve intestinal Stem cells to reestablish intestinal architecture after lethal radiation
  4173. Therapeutic strategies for Duchenne muscular dystrophy: an update
  4174. Aging Biomarkers: From Functional Tests to Multi‐Omics Approaches
  4175. Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy
  4176. Lighting up live-cell and in vivo central carbon metabolism with genetically encoded fluorescent sensors
  4177. Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia
  4178. Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA)
  4179. Treating age-related multimorbidity: the drug discovery challenge
  4180. Live long and prosper: Short-circuiting the process of ageing
  4181. CDK7 inhibitors as anticancer drugs
  4182. SIV infection and the HIV proteins Tat and Nef induce senescence in adipose tissue and human adipose Stem cells, resulting in adipocyte dysfunction
  4183. RUNX transcription factor mediated control of breast cancer Stem cells
  4184. Awakening the HSC: dynamic modeling of HSC maintenance unravels regulation of the TP53 pathway and quiescence
  4185. Proteomics of Long‐Lived Mammals
  4186. Granulins regulate aging kinetics in the adult zebrafish telencephalon
  4187. Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo
  4188. Competitive sgRNA screen identifies p38 MAPK as a druggable target to improve HSPC engraftment
  4189. Is anti-ageing drug discovery becoming a reality?
  4190. Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice
  4191. A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome …
  4192. Brain Age as a Measure of Brain Reserve in Neuropsychiatric Disorders
  4193. Coinhibition of activated p38 MAPKα and mTORC1 potentiates Stemness maintenance of HSCs from SR1-expanded human cord blood CD34+ cells via inhibition of …
  4194. Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs
  4195. Central nervous syStem lesions in Fanconi anemia: Experience from a research center for Fanconi anemia patients
  4196. p16 a biomarker of aging and tolerance for cancer therapy
  4197. Chronic kidney disease: a vicarious relation to premature cell senescence
  4198. Lung regeneration: implications of the diseased niche and ageing
  4199. Review of neuroimaging findings in congenital Zika virus syndrome and its relation to the time of infection
  4200. Networks, Stem Cells, and Longevity
  4201. Angelica sinensis polysaccharides ameliorate 5-flourouracil-induced bone marrow stromal cell proliferation inhibition via regulating Wnt/β-catenin signaling
  4202. Cytotoxic therapy-induced effects on both hematopoietic and marrow stromal cells promotes therapy-related myeloid neoplasms
  4203. Single-cell omics in ageing: a young and growing field
  4204. Selective autophagy in normal and malignant hematopoiesis
  4205. Non-amyloid approaches to disease modification for Alzheimer’s disease: an EU/US CTAD Task Force Report
  4206. Effect of enhancer of zeste homolog 2 mutations on the prognosis of patients with myelodysplastic syndrome: A meta-analysis
  4207. EZH2 in myeloid malignancies
  4208. In vivo gene editing of muscle Stem cells with adeno-associated viral vectors in a mouse model of Duchenne muscular dystrophy
  4209. Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans
  4210. CXCR4 signaling has a CXCL12-independent essential role in murine MLL-AF9-driven acute myeloid leukemia
  4211. Skeletal muscle in health and disease
  4212. The complex role of EZH2 in the tumor microenvironment: opportunities and challenges for immunotherapy combinations
  4213. Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis
  4214. A germ cell ‐specific ageing pattern in otherwise healthy men
  4215. Moderation of mitochondrial respiration mitigates metabolic syndrome of aging
  4216. Aging, obese-insulin resistance, and bone remodeling
  4217. Stochastic non-enzymatic modification of long-lived macromolecules-a missing hallmark of aging
  4218. The Science Behind NMN–A Stable, Reliable NAD+ Activator and Anti-Aging Molecule
  4219. Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions
  4220. Narcissus tazetta bulb extract delays cellular senescence by reducing mTOR pathway activation
  4221. A Distinct Subset of Human Blood Stem Cells Resists Regenerative Stress to Preserve Stemness
  4222. TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis
  4223. Targeting senescent cells for a healthier aging: challenges and opportunities
  4224. High-dimensional single-cell quantitative profiling of skeletal muscle cell population dynamics during regeneration
  4225. cell Therapy for Idiopathic Pulmonary Fibrosis: Rationale and Progress to Date
  4226. Regulation of normal and malignant hematopoiesis by FBOX Ubiquitin E3 Ligases
  4227. TLR2/6 signaling promotes the expansion of premalignant hematopoietic Stem and progenitor cells in the NUP98–HOXD13 mouse model of MDS
  4228. Tailored chromatin modulation to promote tissue regeneration
  4229. Aging-related molecular pathways in chronic cholestatic conditions
  4230. Frailty, physical function and affective status in elderly patients on hemodialysis
  4231. Kynurenine signaling through the aryl hydrocarbon receptor: Implications for aging and healthspan
  4232. Aging: therapeutics for a healthy future
  4233. The aryl hydrocarbon receptor (AhR) in the aging process: another puzzling role for this highly conserved transcription factor
  4234. Effects of the tetrahedral framework nucleic acids on the skeletal muscle regeneration in vitro and in vivo
  4235. Environmental Oxygen is a Key Modulator of Development and Evolution: From Molecules to Ecology: Oxygen‐sensitive pathways pattern the developing organism …
  4236. TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production
  4237. Clinical significance of chemokine receptor antagonists
  4238. Impaired Regeneration in Dystrophic Muscle—New Target for Therapy
  4239. Controlling syStemic inflammation by careful formulation of topical skin care products: our bodies didn’t evolve with all the current chemicals in skin care products
  4240. Cellular and molecular mechanisms of environmental pollutants on hematopoiesis
  4241. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
  4242. Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy
  4243. Social hallmarks of aging: Suggestions for geroscience research
  4244. Rbm24 modulates adult skeletal muscle regeneration via regulation of alternative splicing
  4245. Frailty, a multisyStem ageing syndrome
  4246. Hematopoietic Stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia
  4247. Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G-CSF-, IL-1-, and TNF-independent …
  4248. Major depressive disorder and accelerated aging from a peripheral IGF-1 overexpression perspective
  4249. Platelets in aging and cancer—“double-edged sword”
  4250. The world goes bats: living longer and tolerating viruses
  4251. Tissue engineering and regenerative medicine therapies for cell senescence in bone and cartilage
  4252. Cytological evaluation of enlarged peripheral lymph nodes: An institutional experience from kumaon region of Uttarakhand
  4253. Physical exercise as an immunomodulator of chronic diseases in aging
  4254. Cellular stress responses and dysfunctional Mitochondrial–cellular senescence, and therapeutics in chronic respiratory diseases
  4255. Genetics of frailty: A longevity perspective
  4256. The bright and dark side of extracellular vesicles in the senescence-associated secretory phenotype
  4257. Risk Prediction Model Development for Late On-Set Breast Cancer Screening in Low-and Middle-Income Societies: A Model Study for North Cyprus
  4258. The self-fulfilling prophecy of pulmonary fibrosis: a selective inspection of pathological signalling loops
  4259. Regulatory role of exercise-induced autophagy for sarcopenia
  4260. Understanding Bone Marrow Interactions Which Drive Aging of Hematopoietic Stem Cells
  4261. Mechanisms and origins of spinal pain: from molecules to anatomy, with diagnostic clues and imaging findings
  4262. CRISPR‐Cas9–induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression
  4263. Understanding Bone Marrow Interactions which Drive Aging of Hematopoietic Stem Cells
  4264. Methionine dependence of cancer
  4265. A survey of essential genome stability genes reveals that replication stress mitigation is critical for peri-implantation embryogenesis
  4266. Impact of Epigenetics on Complications of Fanconi Anemia: The Role of Vitamin D-Modulated Immunity
  4267. Exosomes can Regenerate Your Stem Cells
  4268. Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis
  4269. BMAL1 Modulates Epidermal Healing in a Process Involving the Antioxidative Defense Mechanism
  4270. Wwox deficiency causes downregulation of prosurvival ERK signaling and abnormal homeostatic responses in mouse skin
  4271. Role of age-related mitochondrial dysfunction in sarcopenia
  4272. The biphasic and age-dependent impact of Klotho on hallmarks of aging and skeletal muscle function
  4273. Bone Marrow Failure Disorders in the Adolescent Female
  4274. Senescence and cancer: a review of clinical implications of senescence and senotherapies
  4275. Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells
  4276. An immune-cell signature of bacterial sepsis
  4277. Role of senescence and neuroprotective effects of telomerase in neurodegenerative diseases
  4278. The biology of aging and cancer: a complex association
  4279. Aging-related changes in the gene expression profile of human lungs
  4280. Epidemiology and risk factors of chronic obstructive pulmonary disease in Suzhou: a population-based cross-sectional study
  4281. The genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistance
  4282. Aging fits the disease criteria of the International Classification of Diseases
  4283. Recent advances in the treatment of osteoarthritis
  4284. Calorie restriction and aging in humans
  4285. The MLL/SET family and haematopoiesis
  4286. Acute Kidney Injury and Cytokines
  4287. ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly
  4288. Sclerostin and vascular pathophysiology
  4289. Overfeeding and Substrate Availability, But Not Age or BMI, Alter Human Satellite cell Function
  4290. Integrin-mediated adhesions in regulation of cellular senescence
  4291. MicroRNAs, DNA damage response and ageing
  4292. Insights into the conserved regulatory mechanisms of human and yeast aging
  4293. Mitochondrial Priming of Tumor Initiating Cells Involves Repression of Mitochondrial Fission Activity Towards Redox Regulation of the cell Cycle Regulator Cyclin E
  4294. Runx1 Gene in Acute Myeloid Leukemia: Expression Level Significance and Impact on Clinical Features
  4295. circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan
  4296. Aryl hydrocarbon receptor connects dysregulated immune cells to atherosclerosis
  4297. 1, 25‐Dihydroxyvitamin D protects against age‐related osteoporosis by a novel VDR‐Ezh2‐p16 signal axis
  4298. Endothelial mTOR maintains hematopoiesis during aging
  4299. POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern
  4300. Model-based inference and classification of immunologic control mechanisms from TKI cessation and dose reduction in patients with CML
  4301. Evaluation via supervised machine learning of the broiler pectoralis major and liver transcriptome in association with the muscle myopathy wooden breast
  4302. Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age–specific mouse model
  4303. Cellular senescence and Alzheimer disease: the egg and the chicken scenario
  4304. Frailty as a phenotypic manifestation of underlying oxidative stress
  4305. Neuronal mechanisms that drive organismal aging through the lens of perception
  4306. Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo
  4307. The role of cellular senescence in ageing and endocrine disease
  4308. The Role of Nrf2 in Brain Cellular Senescence
  4309. Mitophagy and mitochondrial dysfunction in cancer
  4310. Muscle, bone, and fat crosstalk: the biological role of myokines, osteokines, and adipokines
  4311. Lung epithelium damage in COPD–an unstoppable pathological event?
  4312. Cellular senescence-mediated exacerbation of Duchenne muscular dystrophy
  4313. Age‐related factors that affect B cell responses to vaccination in mice and humans
  4314. Pro-senescence and anti-senescence mechanisms of cardiovascular aging: cardiac MicroRNA regulation of longevity drug-induced autophagy
  4315. Epigenetic clock measuring age acceleration via DNA methylation levels in blood is associated with decreased oocyte yield
  4316. Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression
  4317. Integrating the Science of Aging and Environmental Health Research
  4318. Autophagy‐Sirt3 axis decelerates hematopoietic aging
  4319. Iron and physical activity: Bioavailability enhancers, properties of black pepper (bioperine®) and potential applications
  4320. DNA Damage and the Maintenance of Nuclear Genome Integrity in Aging and Associated Phenotypes
  4321. Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease
  4322. Hepatic stellate cell –specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis
  4323. Effect of age on the cardiovascular remodelling induced by chronic intermittent hypoxia as a murine model of sleep apnoea
  4324. Integration Analysis of Differential Expressed Genes Regulated by Differential Methylated Regions for Predicting Prognosis in Human Colon Cancer
  4325. Influence of aging on deterioration of patients with COVID-19
  4326. Gene co-expression network for analysis of plasma exosomal miRNAs in the elderly as markers of aging and cognitive decline
  4327. Anti-aging role of Chinese herbel medicine: an overview of scientific evidence from 2008 to 2018
  4328. The secretory senescence of the airway
  4329. Pathogenesis of aging and age-related comorbidities in people with HIV: highlights from the HIV ACTION workshop
  4330. The information theory of aging: Hacking immortality?
  4331. DNA Repair in the Development of Human Diseases and Therapy
  4332. Limiting Self-Renewal of the Basal Compartment Induces Differentiation and Alters Evolution of Mammary Tumors
  4333. The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy
  4334. The genetics of human ageing
  4335. Epigenetic changes during ageing and their underlying mechanisms
  4336. Frailty prevalence and agreement between assessment tools in elderly patients of Western India
  4337. ISLR regulates skeletal muscle atrophy via IGF1-PI3K/Akt-Foxo signaling pathway
  4338. Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs
  4339. Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain
  4340. Senotherapy: a new horizon for COPD therapy
  4341. Trajectories of aging: how syStems biology in yeast can illuminate mechanisms of personalized aging
  4342. Limiting self-renewal of the basal compartment by PKA activation induces differentiation and alters the evolution of mammary tumors
  4343. MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway
  4344. Hexokinase 2 promotes cell growth and tumor formation through the Raf/MEK/ERK signaling pathway in cervical cancer
  4345. Brain endothelial cells are exquisite sensors of age-related circulatory cues
  4346. Nrf2 in early vascular ageing: Calcification, senescence and therapy
  4347. Clearing techniques for visualizing the nervous syStem in development, injury, and disease
  4348. Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges
  4349. Immortality, Inc.: Renegade Science, Silicon Valley Billions, and the Quest to Live Forever
  4350. Designing neuroreparative strategies using aged regenerating animal models
  4351. Syndrome of persistent inflammation, the immune suppression and catabolism in surgery
  4352. Emerging therapeutic targets for osteoporosis
  4353. Mitochondria, aging, and cellular senescence: implications for scleroderma
  4354. Impact of Bariatric Surgery on Circulating Inflammatory and Pro-vascular Progenitor cell Populations
  4355. Insights into the role of bioactive food ingredients and the microbiome in idiopathic pulmonary fibrosis
  4356. A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson’s disease in older people: An EXosomes in PArkiNson Disease (EXPAND) …
  4357. Obesity and ageing: Two sides of the same coin
  4358. Aging and age-related health effects of ionizing radiation
  4359. Heterogeneity and overlaps in nucleotide excision repair disorders
  4360. Noncoding RNAs controlling telomere homeostasis in senescence and aging
  4361. The Function of the Long Noncoding RNA Growth Arrest Specific 5 in Hematopoietic Stem and Progenitor Cells
  4362. Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases
  4363. The Expression Levels of Klotho, Endothelial Nitrite Oxide Synthetase and Catalase Genes of the Heart Tissues of Young and Old Rats/Genc ve Yasli Ratlarin Kalp …
  4364. Analysis of transcriptional modules during human fibroblast ageing
  4365. Pathobiology of frailty in lung disease
  4366. The enigma of excessively long telomeres in cancer: lessons learned from rare human POT1 variants
  4367. Turning the oxygen dial: balancing the highs and lows
  4368. A Computational Perspective at the Histone Modification Landscape of the Mouse Liver During Aging
  4369. The involvement of stress granules in aging and aging‐associated diseases
  4370. Conditioning Medicine
  4371. Cellular senescence in arterial diseases
  4372. RNA and aging
  4373. Inherited disorders of lysosomal membrane transporters
  4374. Advancements in therapeutic drugs targeting of senescence
  4375. Cellular senescence in kidney fibrosis: Pathologic significance and therapeutic strategies
  4376. The value of imaging and composition-based biomarkers in Duchenne muscular dystrophy clinical trials
  4377. Immortality, Inc: Renegade Scientists, Silicon Valley Gurus, and the Future of Cheating Death
  4378. Regulating methylation at H3K27: a trick or treat for cancer cell plasticity
  4379. OPINION Open Access
  4380. The road ahead for health and lifespan interventions
  4381. Multi-omics network analysis reveals distinct stages in the human aging progression in epidermal tissue
  4382. Epigenetic biomarkers for human sepsis and septic shock: insights from immunosuppression
  4383. Age related changes in the expression of tenascin-c in liver of albino rat
  4384. The role of reactive oxygen species in tumor treatment and its impact on bone marrow hematopoiesis
  4385. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
  4386. Attempts to Quantify Mitochondrial DNA Deletions in Single Drosophila melanogaster Flies
  4387. A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks
  4388. Effects of Low Dose Ionizing Radiation on DNA Damage and Repair Response in Proliferating Muscle Stem Cells
  4389. Extracellular vesicles: recent developments in aging and reproductive diseases
  4390. PKCθ as a target to manipulate satellite cell function
  4391. page Hepatic stellate cell -specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis
  4392. Synthetic immunomodulation with a CRISPR super-repressor in vivo
  4393. Telomere damage induces internal loops that generate telomeric circles
  4394. Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases
  4395. Targeting miRNAs by polyphenols: Novel therapeutic strategy for aging
  4396. Chronic lower extremity ischemia and its association with the frailty syndrome in patients with diabetes
  4397. Inter-organelle membrane contact sites and mitochondrial quality control during aging: A geroscience view
  4398. Unveiling the role of inflammation and oxidative stress on age-related cardiovascular diseases
  4399. Sleep and ageing: from human studies to rodent models
  4400. Protein Structure and Function in Aging and Age-Related Diseases
  4401. Strategies to improve participation of older adults in cancer research
  4402. Mitochondrial MicroRNAs in aging and neurodegenerative diseases
  4403. NADPH oxidase inhibition in fibrotic pathologies
  4404. Ovarian aging increases small extracellular vesicle CD81+ release in human follicular fluid and influences miRNA profiles
  4405. Nutrition in Cancer Therapy in the Elderly—An Epigenetic Connection?
  4406. Exosome-mediated hematopoietic rejuvenation in a humanized mouse model indicate potential for cancer immunotherapy
  4407. Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: therapeutic targets for obesity and type 2 diabetes
  4408. The Role of Mutant DNMT3a in Ageing and in the Regulation of Normal and Malignant Haematopoiesis
  4409. Hypoxia-induced degenerative protein modifications associated with aging and age-associated disorders
  4410. Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway
  4411. SyStematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age
  4412. The sciences of healthy aging await a theory of health
  4413. Respiratory Organ Aging and Cancer
  4414. Epigenetics and ageing
  4415. Determinants of accelerated metabolomic and epigenetic aging in a UK cohort
  4416. STRESS & ACCELERATED AGING
  4417. Characterization of blood markers and their implication in human aging.
  4418. The gut microbiome, aging, and longevity: a syStematic review
  4419. The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein
  4420. Whole-genome sequencing of rare disease patients in a national healthcare syStem
  4421. Association between Nrf2 and CDKN2A expression in patients with end-stage renal disease: a pilot study
  4422. Transposable elements, circular RNAs and mitochondrial transcription in age-related genomic regulation
  4423. The transcriptional regulation by MYSM1 in hematopoietic Stem and progenitor cells
  4424. Prevalence and risk factors of chronic obstructive pulmonary disease among Agriculturists in a rural community, central Thailand
  4425. Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease
  4426. Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
  4427. Protective mechanisms against DNA replication stress in the nervous syStem
  4428. Trained Immunity at a Glance; A Review on the Innate Immune Memory and its Potential Role in Infections, Diseases and New Therapeutic Strategies
  4429. Metformin: An old drug against old age and associated morbidities
  4430. Edible flowers as functional raw materials: A review on anti-aging properties
  4431. Location, location, location: how vascular specialization influences hematopoietic fates during development
  4432. Type I interferon (IFN)-regulated activation of canonical and non-canonical signaling pathways
  4433. Transplantation of marginal organs: immunological aspects and therapeutic perspectives in kidney transplantation
  4434. CDK7 mediates the beta-adrenergic signaling in thermogenic brown and white adipose tissues
  4435. Amelioration of age‐related brain function decline by Bruton’s tyrosine kinase inhibition
  4436. Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos
  4437. Perioperative care of geriatric patients
  4438. Male age and andropause
  4439. CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus
  4440. Recent advances in the treatment of osteoarthritis
  4441. Ageing, age-related diseases and oxidative stress: what to do next?
  4442. Mechanisms of aging and potential role of selected polyphenols in extending healthspan
  4443. Dietary antioxidants, epigenetics, and brain aging: A focus on resveratrol
  4444. From Fruit Flies to the Frontline: Slow Science in a Demanding Medical Climate
  4445. The geroscience agenda: Toxic stress, hormetic stress, and the rate of aging
  4446. Mechanisms of aging and the preventive effects of resveratrol on age-related diseases
  4447. Structural features of nucleoprotein CST/shelterin complex involved in the telomere maintenance and its association with disease mutations
  4448. Male Age and Andropause 36
  4449. Why we should use topological data analysis in ageing: towards defining the “topological shape of ageing”
  4450. Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose
  4451. The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its essential role in neurodevelopment and aging
  4452. Crosstalk of Molecular Signaling in Hepatocellular Carcinoma
  4453. Curcumin in age-related diseases
  4454. Biological aging and the cellular pathogenesis of Huntington’s disease
  4455. Small‐molecule inhibition of aging‐associated chromosomal instability delays cellular senescence
  4456. Platelet activation is triggered by factors secreted by senescent endothelial HMEC-1 cells in vitro
  4457. Air space distension precedes spontaneous fibrotic remodeling and impaired cholesterol metabolism in the absence of surfactant protein C
  4458. Frailty, cognition, and falls
  4459. Alternative pathways of IL-1 activation, and its role in health and disease
  4460. CXCL12-CXCR4 Interplay Facilitates Palatal Osteogenesis in Mice
  4461. Mouse models for muscular dystrophies: an overview
  4462. Extra virgin olive oil polyphenols: Modulation of cellular pathways related to oxidant species and inflammation in aging
  4463. Resveralogues: from novel ageing mechanisms to new therapies?
  4464. NMR-based metabonomic analysis of HUVEC cells during replicative senescence
  4465. Molecular Biomarkers of Aging Studies in Humans
  4466. Research progress of mTOR inhibitors
  4467. Testing Sulforaphane for Chemoprevention Against Ageing and Functional Decline in Male Drosophila Models
  4468. Characterization of Genome-Wide Binding of Nuclear-Factor IX in Hematopoietic Progenitor Cells
  4469. CDK7 inhibitors in cancer therapy: the sweet smell of success?
  4470. Discovery of Senolytics and the Pathway to Early Phase Clinical Trials
  4471. Circular RNAs: New players in Ageing and Age-related Chronic Disease
  4472. Circulating cell -free DNA is predominantly composed of retrotransposable elements and non-telomeric satellite DNA
  4473. A preliminary study to investigate the genetic background of longevity based on whole-genome sequence data of two Methuselah dogs
  4474. Aging: a new perspective on an old issue
  4475. Nicotinamide, a poly [ADP-ribose] polymerase 1 (PARP-1) inhibitor, as an adjunctive therapy for the treatment of Alzheimer’s disease
  4476. Age estimation using DNA methylation technique in forensics: a syStematic review
  4477. Does Diet Have a Role in the Treatment of Alzheimer’s Disease?
  4478. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress
  4479. Cyclin-dependent kinase 7 inhibitors in cancer therapy
  4480. Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression
  4481. Consequences of cell fusion and multinucleation for skeletal muscle development and disease
  4482. The role of Sestrins in the regulation of the aging process
  4483. Redox signalling and ageing: insights from Drosophila
  4484. Accelerating the search for interventions aimed at expanding the health span in humans: the role of epidemiology
  4485. Age-related changes in haematological parameters and biochemical markers of healing in the stomach of rats with acetic acid induced injury
  4486. Flexibility is costly: hidden physiological damage from seasonal phenotypic transitions in heterothermic species
  4487. Mitochondrial Function in Aging
  4488. Oxidative Stress and Dietary Antioxidants in Neurological Diseases
  4489. THE IMMORTALITY IMPULSE AND JEWISH TRADITION
  4490. Anti-cancer Dynamics of Natural Phytochemical Inhibitors of Cyclin-Dependent Kinases
  4491. Searching for the mechanisms of mammalian cellular aging through underlying gene regulatory networks
  4492. Ribosome, protein synthesis, and aging
  4493. Understanding the heterogeneity of senescence and ageing at the single-cell level
  4494. EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells
  4495. CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer
  4496. Still living better through chemistry: An update on caloric restriction and caloric restriction mimetics as tools to promote health and lifespan
  4497. Changes in RNA regulatory processes during mammalian ageing
  4498. Time-restricted feeding prolongs lifespan in Drosophila in a peripheral clock-dependent manner
  4499. Telomeres and telomere length: a general overview
  4500. The relationship between nutrients and biological aging
  4501. Investigating the Role of CDK11 in Animal Cytokinesis
  4502. Investigating the Effects of Lestaurtinib on Skeletal Muscle Regeneration
  4503. Macrophage immunometabolism and inflammaging: roles of mitochondrial dysfunction, cellular senescence, CD38, and NAD
  4504. The study of transcription factors SCL and LYL1 in normal and malignant haematopoiesis
  4505. Sarcoplasmic reticulum Ca2+ dynamics in aging Drosophila and correlation with sarcopenia
  4506. Calcium-activated potassium channels: Implications for aging and age-related neurodegeneration
  4507. Isolated Congenital Asplenia (ICA) and Mutations in RPSA
  4508. eIF2B extends lifespan through inhibition of the integrated stress response
  4509. Interleukin-21 Deficiency
  4510. Implications of Chronic Infection on Skeletal Muscle Immunity, Regeneration, and Function
  4511. Current nutritional and pharmacological anti-aging interventions
  4512. Psychological Stress and Breast Cancer
  4513. Idiopathic interstitial pneumonias
  4514. The Epigenome of Aging
  4515. Stress influence in neurodegeneration. Unravelling the mechanisms underlying stress response in brain ageing by 11ß-HSD1 inhibition
  4516. Vacuolar transporter Mnr2 safeguards mitochondrial integrity in aged cells
  4517. Interstitial lung diseases in children
  4518. Gut microbiota and old age: Modulating factors and interventions for healthy longevity
  4519. Epigenetics in Exercise
  4520. Resetting proteostasis with ISRIB prevents pulmonary fibrosis
  4521. Semelparity and Reproductive Death in Caenorhabditis elegans
  4522. Evolution and treatment of idiopathic pulmonary fibrosis
  4523. 20 Biological Rhythms and Aging
  4524. The Role of SOX2 in Regulating Metabolism and Enzalutamide Resistance in Prostate Cancer
  4525. CENTER HEARTBEAT
  4526. MRE11-Dependent Instability in Mitochondrial DNA Fork Protection Activates cGAS Inflammation
  4527. Beyond host defense: Deregulation of Drosophila immunity and age-dependent neurodegeneration
  4528. Biological Rhythms and Aging
  4529. Aus dem Institut für Arbeits-, Sozial-und Umweltmedizin der Heinrich-Heine-Universität Düsseldorf Direktor: Univ.-Prof. Dr. Peter Angerer
  4530. Genetic epidemiology of markers of genomic ageing
  4531. The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia
  4532. Spatiotemporal changes in the human lens proteome: Critical insights into long-lived proteins
  4533. The Role of the Circadian Clock in Hippocampal Aging and as a Therapeutic Target in Alzheimer’s Disease
  4534. Dissecting Dystrophin’s Roles, Subcellular Organization, and Functional Network in Drosophila Oogenesis
  4535. Klotho, aging, and the failing kidney
  4536. From Mice to Humans: An Overview of the Potentials and Limitations of Current Transgenic Mouse Models of Major Muscular Dystrophies and Congenital Myopathies
  4537. The crossroad of phosphatase and kinase signaling in cancer
  4538. Deciphering the mechanism of adult reproductive diapause in C. elegans
  4539. Precision modeling of breast cancer in the CRISPR era
  4540. A RecQ helicase in disguise: Characterization of the unconventional Structure and Function of the human Genome Caretaker RecQ4
  4541. Peanut Protein Supplemenation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Individuals
  4542. The chemical exposome of human aging
  4543. Spontaneous replication fork collapse regulates telomere length homeostasis in wild type cells
  4544. Investigating neuroregulation of sebaceous gland biology
  4545. Oxidative modification of SOD1 as a mechanism of pathological aging
  4546. The parasitic worm product ES-62 promotes health-and life-span in a high calorie diet-accelerated mouse model of ageing
  4547. Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases
  4548. Obesity: A Bad Partner for the Elderly
  4549. Longevity: translation of aging theories into action
  4550. Modifying the proteostasis status: the role of cross-organelle communication
  4551. Characterisation of senescence entry point using long-lived mutants and intervention related to ageing factors ERC and ROS
  4552. Age-dependent effects of short-term intermittent fasting and rapamycin treatment in zebrafish (danio rerio) brain
  4553. The Fanconi Anaemia Group M (FANCM) Protein and Its Binding Partner FAAP24 Modulate ALT Telomere Maintenance in Human Cells
  4554. Age-dependent effects of short-term intermittent fasting and rapamycin treatment in Zebrafish (Danio Rerio) brain
  4555. High dose intra-venous Vitamin C administration to prevent mortality in patients with sepsis: A Randomized, Double-blind, Placebo-controlled trial
  4556. Examining the Role of Microglia in Niemann-Pick Type C
  4557. Contribution of histone modifications to double-strand break repair and aging
  4558. Loco-Regional Treatment of Cutaneous Melanoma
  4559. Genetic code expansion for ageing study
  4560. Measurement of Biological Age in Humans: Approach, Comparability, and Critical Perspective
  4561. Novel functional domains in the muscle disease associated protein KY
  4562. Epigenetics of Schizophrenia and Suicidality
  4563. Investigating the Regulation of Ras Signalling by ROS in Caenorhabditis elegans
  4564. Coevolution of sociality and ageing in animal societies
  4565. Hallmarks of aging in kidney from mice submitted to genetic and nutritional intervention
  4566. Sex-differences shape memory capacity declining during ageing: rescue effects of voluntary exercise
  4567. Escape of hair follicle Stem cells causes Stem cell exhaustion during aging
  4568. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural Stem cell exhaustion and dysfunction
  4569. Arabidopsis casein kinase 2 triggers Stem cell exhaustion under Al toxicity and phosphate deficiency through activating the DNA damage response pathway
  4570. Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging
  4571. FANCD2 and HES1 suppress inflammation‐induced PPARɣ to prevent haematopoietic Stem cell exhaustion
  4572. Is Avoiding Stem cell exhaustion the New Therapeutic Approach in Colitis?
  4573. TNFα Controls the Delicate Balance between Erythropoiesis and Stem cell exhaustion during Inflammatory Stress
  4574. Epigenetic alterations in Stem cell ageing—a promising target for age-reversing interventions?
  4575. FAM122A is required for hematopoietic Stem cell function
  4576. Application of mesenchymal Stem cell therapy for aging frailty: From mechanisms to therapeutics
  4577. Sestrins regulate muscle Stem cell metabolic homeostasis
  4578. A Review of the Impact of Calorie Restriction on Stem cell Potency
  4579. Arabidopsis casein kinase 2 triggers Stem cell exhaustion under Al toxicity and phosphate deficiency through activating the DNA damage response pathway
  4580. Strategies to Protect Hematopoietic Stem Cells from Culture-induced Stress Conditions.
  4581. Mitochondrial Contributions to Hematopoietic Stem cell Aging
  4582. cell size is a determinant of Stem cell potential during aging
  4583. cell and cell -Free Therapies to Counteract Human Premature and Physiological Aging: MSCs Come to Light
  4584. Metabolic Coordination of Stem cell Fate Controls Tumor Initiation and Tissue Repair
  4585. Immune reconstitution in the aging host: Opportunities for mechanism-based therapy in allogeneic hematopoietic cell transplantation
  4586. Ageing human bone marrow mesenchymal Stem cells have depleted NAD (P) H and distinct multispectral autofluorescence
  4587. Prolonged maintenance of hematopoietic Stem cells that escape from thrombopoietin deprivation
  4588. mTOR signaling as a regulator of hematopoietic Stem cell fate
  4589. Healthy ageing and spermatogenesis
  4590. Mitochondria as signaling organelles control mammalian Stem cell fate
  4591. Meloxicam with Filgrastim may Reduce Oxidative Stress in Hematopoietic Progenitor Cells during Mobilization of Autologous Peripheral Blood Stem Cells in Patients …
  4592. Opportunities and challenges in Stem cell aging
  4593. Cryptomphalus aspersa Eggs Extract Potentiates Human Epidermal Stem cell Regeneration and Amplification
  4594. ESC-sEVs rejuvenate aging hippocampal NSCs by transferring SMADs to regulate the MYT1-Egln3-Sirt1 axis
  4595. Mesenchymal Stem cell Transplantation for the Treatment of Cognitive Frailty
  4596. Functional genomics of ageing: implications of chromatin landscape and beyond
  4597. Inflammation, a common mechanism in frailty and COVID‐19, and Stem cells as a therapeutic approach
  4598. Impact of Selenium on Biomarkers and Clinical Aspects Related to Ageing. A Review
  4599. Aging delays epimorphic regeneration in mice
  4600. Rejuvenation of senescent bone marrow mesenchymal stromal cells by pulsed triboelectric stimulation
  4601. Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner …
  4602. Muscle Stem cell quiescence: controlling Stemness by staying asleep
  4603. Mediterranean diet and the hallmarks of ageing
  4604. Antioxidant effects of caffeic acid lead to protection of drosophila intestinal Stem cell aging
  4605. Generation of new in vivo tools to study healthy and pathological aging of the nervous syStem
  4606. Pharmacological and non-pharmacological interventions for aging
  4607. Metabolism and chromatin: A dynamic duo that regulates development and ageing: Elucidating the metabolism‐chromatin axis in bone‐marrow mesenchymal Stem …
  4608. Prognostic impact of serum CXC chemokine ligands 4 and 7 on myelodysplastic syndromes post allogeneic hematopoietic cell transplant
  4609. Hair Follicle Stem cell Regeneration in Aging
  4610. Late/post-term decidual basalis-derived mesenchymal Stem/stromal cells show evidence of advanced ageing and downregulation of microRNA-516b-5p
  4611. Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients
  4612. Intracrine Vascular Endothelial Growth Factor Maintains Hippocampal Neural Stem cell Quiescence
  4613. Mediterranean diet and the hallmarks of ageing
  4614. Exercise to Mend Aged-tissue Crosstalk in Bone Targeting Osteoporosis & Osteoarthritis
  4615. Calcium signaling as an integrator and decoder of niche factors to control somatic Stem cell quiescence and activation
  4616. The antiaging role of oxytocin
  4617. Theories of Stem cell aging
  4618. Hematopoietic Stem cell (HSC) divisional memory: The journey of mitochondrial metabolism through HSC division
  4619. Balancing DNA repair to prevent ageing and cancer
  4620. Clinical features, pathophysiology and therapy of Poor Graft Function Post Allogeneic Stem cell Transplantation
  4621. New insights of epigenetics in vascular and cellular senescence
  4622. Isolation and characterization of neural Stem/progenitor cells in the subventricular zone of the naked mole-rat brain
  4623. Mitochondria Turnover and Lysosomal Function in Hematopoietic Stem cell Metabolism
  4624. Hematopoietic versus leukemic Stem cell quiescence: Challenges and therapeutic opportunities
  4625. Cancer treatment-induced accelerated aging in cancer survivors: biology and assessment
  4626. Nutrition and the Hallmarks of Aging
  4627. Aging-induced Stem cell dysfunction: Molecular mechanisms and potential therapeutic avenues
  4628. IL-10–producing innate lymphoid cells increased in patients with house dust mite allergic rhinitis following immunotherapy
  4629. Periodontitis and Accelerated Biological Aging: A Geroscience Approach
  4630. Single or Repeated Ablation of Mouse Olfactory Epithelium by Methimazole
  4631. Epigenetic and metabolic regulation of epidermal homeostasis
  4632. Aging and hematopoiesis
  4633. Dermal Pericytes Exhibit Declined Ability to Promote Human Skin Regeneration with Ageing in 3D Organotypic Culture Models
  4634. Srebf1c preserves hematopoietic Stem cell function and survival as a switch of mitochondrial metabolism
  4635. Stem‐cell ‐based therapies for retinal degenerative diseases: Current challenges in the establishment of new treatment strategies
  4636. Persistent NF-κB activation in muscle Stem cells induces proliferation-independent telomere shortening
  4637. Taurine represses age‐associated gut hyperplasia in Drosophila via counteracting endoplasmic reticulum stress
  4638. Why Stem/progenitor cells lose their regenerative potential
  4639. Advances in preclinical hematopoietic Stem cell models and possible implications for improving therapeutic transplantation
  4640. OGT regulates hematopoietic Stem cell maintenance via PINK1-dependent mitophagy
  4641. Epigenetic plasticity and redox regulation of neural Stem cell state and fate
  4642. Empowering muscle Stem cells for the treatment of Duchenne muscular dystrophy
  4643. Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis
  4644. Data on RNA-seq analysis of Drosophila melanogaster during ageing
  4645. Treatment-Free Remission: the New Goal in CML Therapy
  4646. Stem cell aging and wound healing
  4647. Immunity, Stem cells, and aging
  4648. Muscle Stem cell adaptations to cellular and environmental stress
  4649. ATP-dependent chromatin remodelers in ageing and age-related disorders
  4650. The Future of Pensions and Life Extension
  4651. The tumor suppression theory of aging
  4652. Unraveling the Big Sleep: Molecular Aspects of Stem cell Dormancy and Hibernation
  4653. CrossTORC and WNTegration in Disease: Focus on Lymphangioleiomyomatosis
  4654. The potential of calorie restriction and calorie restriction mimetics in delaying aging: focus on experimental models
  4655. Neural Stem cell -derived extracellular vesicles counteract insulin resistance-induced senescence of neurogenic niche
  4656. Cytokine combinations for human blood Stem cell expansion induce cell -type–and cytokine-specific signaling dynamics
  4657. Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling
  4658. ATM modulates subventricular zone neural Stem cell maintenance and senescence through Notch signaling pathway
  4659. Transcriptional and epigenetic control of hematopoietic Stem cell fate decisions in vertebrates
  4660. TWIST1 preserves hematopoietic Stem cell function via the CACNA1B/Ca2+/mitochondria axis
  4661. Aging clocks & mortality timers, methylation, glycomic, telomeric and more. A window to measuring biological age
  4662. Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal Stem cell population
  4663. Impact of selenium on biomarkers and clinical aspects related to ageing. A review
  4664. N1-acetylspermidine is a determinant of hair follicle Stem cell fate
  4665. Stem cell quiescence: the challenging path to activation
  4666. Cancer Treatment-Induced Accelerated Aging in Cancer Survivors: Biology and Assessment. Cancers 2021, 13, 427
  4667. Chaperone-mediated autophagy sustains haematopoietic Stem–cell function
  4668. Stem cell rejuvenation by restoration of youthful metabolic compartmentalization
  4669. Aging and Stem cell renewal
  4670. The aryl hydrocarbon receptor modulates murine hematopoietic Stem cell homeostasis and influences lineage-biased Stem and progenitor cells
  4671. Dynamic regulation of mitochondrial-endoplasmic reticulum crosstalk during Stem cell homeostasis and aging
  4672. Hair-Follicle Mesenchymal Stem cell Activity during Homeostasis and Wound Healing
  4673. Metabolic Regulation of Stem Cells in Aging
  4674. Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating Neural Stem cell activity
  4675. The AGE Presents Introduction to Geroscience video lecture series
  4676. Age-Related Metabolic Pathways Changes in Dental Follicles: A Pilot Study
  4677. The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic Stem cell function
  4678. CD63 acts as a functional marker in maintaining hematopoietic Stem cell quiescence through supporting TGFβ signaling in mice
  4679. Pharmacological Inhibition of p38 MAPK Rejuvenates Bone Marrow Derived-Mesenchymal Stromal Cells and Boosts their Hematopoietic Stem cell -Supportive Ability
  4680. Peptidylarginine deiminase IV (PADI4) is not essential for cell -autonomous HSC maintenance and normal haematopoiesis
  4681. Dental pulp Stem cell -derived small extracellular vesicle in irradiation-induced senescence
  4682. Epimorphic regeneration of the mouse digit tip is finite
  4683. Epithelial Stem cell homeostasis in Meibomian gland development, dysfunction, and dry eye disease
  4684. Acute intestinal inflammation depletes/recruits histamine-expressing myeloid cells from the bone marrow leading to exhaustion of MB-HSCs
  4685. Differential regulation of β-catenin-mediated transcription via N-and C-terminal co-factors governs identity of murine intestinal epithelial Stem cells
  4686. The Impact of Sedentary Lifestyle, High-fat Diet, Tobacco Smoke, and Alcohol Intake on the Hematopoietic Stem cell Niches
  4687. Role of biological markers in Stem cell aging and its implications in therapeutic processes
  4688. IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock
  4689. Wnt Signaling Rescues Amyloid Beta-Induced Gut Stem cell Loss
  4690. Stabilization of heterochromatin by CLOCK promotes Stem cell rejuvenation and cartilage regeneration
  4691. DNA Damage-Induced Inflammatory Microenvironment and Adult Stem cell Response
  4692. Metabolic Control of Stem cell Ageing and Longevity through Caloric Restriction
  4693. Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer …
  4694. Effects of caloric restriction on the antagonistic and integrative hallmarks of aging
  4695. Hormetic ER Stress in Hematopoietic Stem Cells
  4696. Advantages and challenges of Stem cell therapy for osteoarthritis
  4697. NAP1L2 drives mesenchymal Stem cell senescence and suppresses osteogenic differentiation
  4698. Accelerated lung aging in COPD: finding potential anti-aging therapies
  4699. Enhanced germline Stem cell longevity in Drosophila diapause
  4700. A comprehensive transcriptome signature of murine hematopoietic Stem cell aging
  4701. Is Myelodysplasia a Consequence of Normal Aging?
  4702. The central role of DNA damage in the ageing process
  4703. Epithelial Stem cells at the intersection of tissue regeneration and pulmonary fibrosis
  4704. The FOXO signaling axis displays conjoined functions in redox homeostasis and Stemness
  4705. Yin and Yang: The dual effects of interferons on hematopoiesis
  4706. Lipid metabolism in focus: how the build-up and breakdown of lipids affects Stem cells
  4707. Hematopoiesis, Inflammation and Aging—The Biological Background and Clinical Impact of Anemia and Increased C-Reactive Protein Levels on Elderly Individuals
  4708. Metabolic and Redox regulation of cardiovascular Stem cell biology and pathology
  4709. Control of satellite cell function in muscle regeneration and its disruption in ageing
  4710. The Yin and Yang of Immunity in Stem cell Decision Guidance in Tissue Ecologies: An Infection Independent Perspective
  4711. Mechanisms of adipose-derived Stem cell aging and the impact on therapeutic potential
  4712. Cyclin‐Dependent Kinase 4 expression alters the number of keratinocyte Stem cells in the mouse hair follicle
  4713. A comprehensive transcriptome signature of murine hematopoietic Stem cell aging
  4714. An NRF2 perspective on Stem cells and ageing
  4715. Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle Stem cell functionality
  4716. Disqueratosis congénita y absceso del siStema nervioso central
  4717. Inflammation, aging and hematopoiesis: A complex relationship
  4718. Phenotypical changes of hematopoietic Stem and progenitor cells in sepsis patients: correlation with immune status?
  4719. Interpreting Geroscience-Guided Biomarker Studies
  4720. The Act of controlling adult Stem cell dynamics: insights from animal models
  4721. Regulation of spermatogenic Stem cell homeostasis by mitogen competition in an open niche microenvironment
  4722. CDK19 regulates the proliferation of hematopoietic Stem cells and acute myeloid leukemia cells by suppressing p53-mediated transcription of p21
  4723. Inherited DNA repair defects disrupt the structure and function of human skin
  4724. Autophagy in Aging and Longevity Exemplified by the Aging Heart
  4725. LRP5 promotes cancer Stem cell traits and chemoresistance in colorectal cancer
  4726. Persistent JunB activation in fibroblasts disrupts Stem cell niche interactions enforcing skin aging
  4727. Novel pharmacotherapy: NNI-362, an allosteric p70S6 kinase stimulator, reverses cognitive and neural regenerative deficits in models of aging and disease
  4728. Inflammation Regulates Haematopoietic Stem Cells and Their Niche
  4729. The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration
  4730. Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic Stem cell
  4731. Coloniality, clonality, and modularity in animals: The elephant in the room
  4732. Adipose‐derived Stem cells regulate metabolic homeostasis and delay aging by promoting mitophagy
  4733. Loss of TET2 Tips the Scales Toward Tumorigenesis
  4734. An integrated network analysis approach to identify potential key genes, transcription factors, and microRNAs regulating human hematopoietic Stem cell aging
  4735. Nanomaterials and aging
  4736. Evolutionary perspectives on cancer and aging
  4737. Strategies for late phase preclinical and early clinical trials of senolytics
  4738. Iron overload-induced oxidative stress in myelodysplastic syndromes and its cellular sequelae
  4739. Non-canonical functions of the ARF tumor suppressor in development and tumorigenesis
  4740. The caloric restriction fallacy, rodent diet aids and the tumor suppression theory of aging
  4741. A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases
  4742. Formation and integration of new neurons in the adult hippocampus
  4743. Microbial sensing by hematopoietic Stem and progenitor cells
  4744. Organoids: An Emerging Tool to Study Aging Signature across Human Tissues. Modeling Aging with Patient-Derived Organoids
  4745. Understanding the hedgehog signaling pathway in acute myeloid leukemia Stem cells: A necessary step toward a cure
  4746. From development toward therapeutics, a collaborative effort on blood progenitors
  4747. Hallmarks of T cell aging
  4748. Regulation of cell polarity and tissue architecture in epidermal aging and cancer
  4749. Hallmarks of aging in macrophages: Consequences to skin inflammaging
  4750. Lycium barbarum polysaccharides in ageing and its potential use for prevention and treatment of osteoarthritis: a syStematic review
  4751. Stem cell therapies for progressive multiple sclerosis
  4752. What Is Caloric Restriction?
  4753. The elevated level of IL-1α in the bone marrow of aged mice leads to MSC senescence partly by down-regulating Bmi-1
  4754. Stem Cells and Aging
  4755. Marrow failure and aging: the role of “Inflammaging”
  4756. Differential regulation of฀-catenin-mediated transcription via N-and C-terminal co-factors governs identity of murine intestinal epithelial Stem cells
  4757. Hematopoietic Stem cell Integrity Is Dependent on Znf143 Maintenance of Chromosome Structure
  4758. Telomeres: history, health, and hallmarks of aging
  4759. H syndrome: A review of treatment options and a hypothesis of phenotypic variability
  4760. Myc determines the functional age state of oligodendrocyte progenitor cells
  4761. Scinderin promotes fusion of electron transport chain dysfunctional muscle Stem cells with myofibers
  4762. Cognitive dysfunction prevalence and associated factors in older breast cancer survivors
  4763. Longevity leap: Mind the healthspan gap
  4764. The effect of cultivation passaging on the relative telomere length and proliferation capacity of dental pulp Stem cells
  4765. Previews
  4766. Identifying biomarkers for biological age: geroscience and the ICFSR task force
  4767. Phenotypic heterogeneity in individuals with MECOM variants in 2 families
  4768. Excessive fetal growth affects HSC quiescence maintenance through epigenetic programming of EGR1 transcriptional network
  4769. Donate Cryptocurrency Join the Lifespan Heroes Today! Longevity Events Ending Age-Related Diseases 2022
  4770. Dlk1 dosage regulates hippocampal neurogenesis and cognition
  4771. Regenerative Medicine and the Hope for a Cure
  4772. DNA damage response priming by CK2: a matter of life or cell death in root apical meriStems
  4773. Licochalcone A activation of glycolysis pathway has an anti-aging effect on human adipose Stem cells
  4774. Inauguration of a unique journal Ageing and Neurodegenerative Diseases: A new beginning seeking cures for age-related neurodegenerative diseases
  4775. MDM4: A Novel Molecular Target for Treating Idiopathic Pulmonary Fibrosis Associated with Aging
  4776. Metabolic Analysis of Mouse Hematopoietic Stem and Progenitor Cells
  4777. Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal Stem cells
  4778. Continuous NF-κB pathway inhibition promotes expansion of human phenotypical hematopoietic Stem/progenitor cells through metabolism regulation
  4779. Human Aging: From Cellular Mechanisms to Therapeutic Strategies
  4780. Aging of hematopoietic Stem cells: Insight into mechanisms and consequences
  4781. Aging and Cancer
  4782. Increased LGR6 Expression Sustains Long-Term Wnt Activation and Acquisition of Senescence in Epithelial Progenitors in Chronic Lung Diseases
  4783. Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells
  4784. The hematopoietic Stem/progenitor cell response to hemorrhage, injury, and sepsis: a review of pathophysiology
  4785. Aging-associated immune syStem changes in multiple myeloma: The dark side of the moon.
  4786. Transcriptomic and epigenomic profiling of young and aged spermatogonial Stem cells reveals molecular targets regulating differentiation
  4787. Gender and Age Differences in the Hepatic Consequences of “Humanized” Bile Acid Compositions in Mice
  4788. Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy
  4789. GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model
  4790. CXXC5 variant in an immunodeficient patient with a progressive loss of hematopoietic cells
  4791. Investigation of the role of inflammation in myeloproliferative neoplasms
  4792. Modeling Neuroregeneration and Neurorepair in an Aging Context: The Power of a Teleost Model
  4793. Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal Stem cells
  4794. A new era for research into aging
  4795. Epigenetic control of muscle Stem cells: time for a new dimension
  4796. Who gets a license: DNA synthesis in quiescent cells re-entering the cell cycle
  4797. Aging, Bone Marrow and Next-Generation Sequencing (NGS): Recent Advances and Future Perspectives
  4798. Muscle Stem cell Fate is Directed by the Mitochondrial Fusion Protein OPA1
  4799. The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged human placenta-derived mesenchymal Stem cells in vitro
  4800. Primary Ovarian Failure in Addition to Classical Clinical Features of Coats Plus Syndrome in a Female Carrying 2 Truncating Variants of CTC1
  4801. Epigenetic modifications in muscle regeneration and progression of Duchenne muscular dystrophy
  4802. Epigenetic Clocks–What are they?
  4803. The gut microbiome, metformin, and aging
  4804. Implications of hematopoietic Stem cells heterogeneity for gene therapies
  4805. Biological mechanisms of aging predict age-related disease multimorbidities in patients
  4806. CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib
  4807. Epigenetic induction of mitochondrial fission is required for maintenance of liver cancer–initiating cells
  4808. Reviewing Cold Therapy for Longevity
  4809. Aging Atlas: a multi-omics database for aging biology
  4810. Nutritional Mediators of Cellular Decline and Mitochondrial Dysfunction in Older Adults
  4811. Healing after COVID-19: are survivors at risk for pulmonary fibrosis?
  4812. Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook
  4813. The killifish visual syStem as an in vivo model to study brain aging and rejuvenation
  4814. Effects of cardiotoxins on cardiac Stem and progenitor cell populations
  4815. Genomic instability as a main driving factor of unsuccessful ageing: potential for translating the use of micronuclei into clinical practice
  4816. RNF43: A Biomarker With Potential Ramifications for Therapeutic Intervention in Gastric Cancer
  4817. Protein arginine methyltransferase 5: a potential cancer therapeutic target
  4818. PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS‐STING‐Mediated Interferon Response
  4819. Hallmarks of aging and immunosenescence: Connecting the dots
  4820. Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
  4821. Disease modifying agents of myeloproliferative neoplasms: a review
  4822. Regulation of the wound healing response during aging
  4823. Aging through an epitranscriptomic lens
  4824. Cellular senescence in lymphoid organs and immunosenescence
  4825. Analysis of Putative Skeletal Stem Cells Via Single cell RNA Sequencing
  4826. JWA deficiency accelerates aging through disrupting intestinal epithelial homeostasis via Notch1/PPARγ/Stat5 axis
  4827. Senolytic drugs: reducing senescent cell viability to extend health span
  4828. Human primary airway basal cells display a continuum of molecular phases from health to disease in chronic obstructive pulmonary disease
  4829. Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial Stem cells
  4830. Impaired bone marrow microenvironment and Stem cells in transfusion-dependent beta-thalassemia
  4831. Functional heterogeneity of mesenchymal Stem cells from natural niches to culture conditions: implications for further clinical uses
  4832. Mouse Models of Muscle Fibrosis
  4833. Identification of Potential Diagnostic Gene Targets for Pediatric Sepsis Based on Bioinformatics and Machine Learning
  4834. Enhanced self-renewal of human long-term hematopoietic Stem cells by a sulfamoyl benzoate derivative targeting p18INK4C
  4835. The Challenge of Unlocking the Biological Secrets of Aging
  4836. Transcriptome and lipidome profile of human mesenchymal Stem cells with reduced senescence and increased trilineage differentiation ability upon drug …
  4837. Role of cell competition in ageing
  4838. Interferon b drives intestinal regeneration after radiation
  4839. Roles of extracellular vesicles in the aging microenvironment and age‐related diseases
  4840. Pasteurized non-fermented cow’s milk but not fermented milk is a promoter of mTORC1-driven aging and increased mortality
  4841. New Perspectives of Interferon-alpha2 and Inflammation in Treating Philadelphia-negative Chronic Myeloproliferative Neoplasms
  4842. Hypoxia-inducible factor-1α–mediated upregulation of CD99 promotes the proliferation of placental mesenchymal Stem cells by regulating ERK1/2
  4843. Mechanisms of aging in bipolar disorder
  4844. Cystic fibrosis lung disease in the aging population
  4845. The Mediator captures CDK7, an attractive transcriptional target in cancer
  4846. Beyond the storm—subacute toxicities and late effects in children receiving CAR T cells
  4847. Ginsenoside Rg1 as a Potential Regulator of Hematopoietic Stem/Progenitor Cells
  4848. Rejuvenation through iPSCs and reprogramming in vivo and in vitro
  4849. Alternative stromal cell -based therapies for aging and regeneration
  4850. Cancer Stem cells as a source of drug resistance in bone sarcomas
  4851. Early detection of accelerated aging and cellular decline (AACD): A consensus statement
  4852. Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro
  4853. Reduced CXCR4-expression on CD34-positive blood cells predicts outcomes of persons with primary myelofibrosis
  4854. The triad inflammation-microenvironment-tumor initiating cells in leukemia progression
  4855. Single nuclei profiling identifies cell specific markers of skeletal muscle aging, sarcopenia and senescence
  4856. Cellular senescence links mitochondria-ER contacts and aging
  4857. Breathe it in–Spotlight on senescence and regeneration in the lung
  4858. The promising role of autologous and allogeneic mesenchymal stromal cells in managing knee osteoarthritis. What is beyond Mesenchymal stromal cells?
  4859. Repetitive spikes of glucose and lipid induce senescence-like phenotypes of bone marrow Stem cells through H3K27me3 demethylase-mediated epigenetic …
  4860. More Than Skin Deep–the Effects of Ultraviolet Radiation on Cathepsin K and Progerin Expression in Cultured Dermal Fibroblasts
  4861. Obesity, A Condition That Mimics Premature Aging
  4862. Senotherapeutic Drugs: A New Avenue for Skincare?
  4863. The killifish visual syStem as an in vivo model to study brain aging and rejuvenation
  4864. Metformin-induced microRNA-34a-3p downregulation alleviates senescence in human dental pulp Stem cells by targeting CAB39 through the AMPK/mTOR …
  4865. Dopamine signaling regulates hematopoietic Stem and progenitor cell function
  4866. A cellular analysis of meriStem activity at the end of flowering points to cytokinin as a major regulator of proliferative arrest in Arabidopsis
  4867. Dance as physical exercise for older people
  4868. Putative homeostatic role of cancer driver mutations
  4869. From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing
  4870. Molecular SyStems Architecture of Interactome in the Acute Myeloid Leukemia Microenvironment
  4871. How the AHR became important in cancer: The role of chronically active AHR in cancer aggression
  4872. The INSPIRE research initiative: A program for geroscience and healthy aging research going from animal models to humans and the healthcare syStem
  4873. A new era for research into aging
  4874. Age‐related changes in the energy of human mesenchymal Stem cells
  4875. Hutchinson-Gilford progeria syndrome: rejuvenating old drugs to fight accelerated ageing
  4876. Nanocosmeceuticals for the management of ageing: Rigors and Vigors
  4877. RUNX3 overexpression inhibits normal human erythroid development
  4878. Cellular senescence in knee osteoarthritis: molecular mechanisms and therapeutic implications
  4879. Uremic toxins and frailty in patients with chronic kidney disease: A molecular insight
  4880. Immune syStem aging and the aging-related diseases in the COVID-19 era
  4881. Higher Levels of Circulating Osteoprogenitor Cells Are Associated With Higher Bone Mineral Density and Lean Mass in Older Adults: A Cross‐Sectional Study
  4882. Disease pathology in fibrotic interstitial lung disease: is it all about usual interstitial pneumonia?
  4883. Anti-Aging Physiological Roles of Aryl Hydrocarbon Receptor and Its Dietary Regulators
  4884. Hereditary Hemochromatosis Associated With Idiopathic Refractory Aplastic Anemia in a Five-Year-Old Boy: A Case Report
  4885. Anti-aging: senolytics or gerostatics (unconventional view)
  4886. Reprogramming: Emerging Strategies to Rejuvenate Aging Cells and Tissues
  4887. The role of mTOR in age-related diseases
  4888. Function of telomere in aging and age related diseases
  4889. Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic Stem cells in chronic myeloid …
  4890. High Temperature Inhibits The Differentiation of Spermatogonial Stem Cells
  4891. Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution
  4892. Ways to become old: Role of lifestyle in modulation of the hallmarks of aging
  4893. Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia
  4894. cell -centric hypotheses of aging
  4895. Association Between Chronologic Age and Geriatric Assessment–Identified Impairments: Findings From the CARE Registry
  4896. Taking the road less traveled–the therapeutic potential of CBP/β-catenin antagonists
  4897. Safe and Effective Cynomolgus Monkey GLP—Tox Study with Repetitive Intrathecal Application of a TGFBR2 Targeting LNA-Gapmer Antisense Oligonucleotide as …
  4898. An early myelosuppression in the acute mouse sepsis is partly outcome-dependent
  4899. Lung Cancer Stem Cells—Origin, Diagnostic Techniques and Perspective for Therapies
  4900. The role of iron in benign and malignant hematopoiesis
  4901. Transitional dynamics of cancer Stem cells in invasion and metastasis
  4902. Nature or nurture? Role of the bone marrow microenvironment in the genesis and maintenance of myelodysplastic syndromes
  4903. LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
  4904. Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease
  4905. Diet, lipids, and antitumor immunity
  4906. Guanosine primes acute myeloid leukemia for differentiation via guanine nucleotide salvage synthesis
  4907. Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy
  4908. Novel Anti-Inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies
  4909. Single-cell transcriptomics reveal cell type-specific molecular changes and altered intercellular communications in chronic obstructive pulmonary disease
  4910. Deletion of phosphatidylserine flippase β-subunit Tmem30a in satellite cells leads to delayed skeletal muscle regeneration
  4911. Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors
  4912. Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases
  4913. The Aged Intestine: Performance and Rejuvenation
  4914. T-cell Acute Lymphoblastic Leukemia in a Young Adult With Thrombocytopenia-absent Radius Syndrome: A Case Report and Review of the Literature
  4915. To breathe or not to breathe: Understanding how oxygen sensing contributes to age-related phenotypes
  4916. Frailty and HIV: moving from characterization to intervention
  4917. Metabolic decisions in development and disease—a Keystone Symposia report
  4918. High-dimensional single cell mass cytometry analysis of the murine hematopoietic syStem reveals signatures induced by ageing and physiological pathogen …
  4919. Cancer Stem cells and clonal evolution in bone sarcomas
  4920. Age-Related Changes in Bone-Marrow Mesenchymal Stem Cells
  4921. Etiological Analysis of Pancytopenia in a Tertiary Care Hospital
  4922. Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy
  4923. Cypermethrin impairs hippocampal neurogenesis and cognitive functions by altering neural fate decisions in the rat brain
  4924. Interventional Strategies to Delay Aging-Related Dysfunctions of the Musculoskeletal SyStem
  4925. Crosstalk between different DNA repair pathways contributes to neurodegenerative diseases
  4926. Obstructive sleep apnea-hypopnea syndrome as a novel potential risk for aging
  4927. Therapeutic applications of three-dimensional organoid models in lung cancer
  4928. The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia
  4929. Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition
  4930. YY1 involvement in embryonic development and cancer
  4931. The aging lung: Physiology, disease, and immunity
  4932. Immunosenescence in multiple sclerosis: the identification of new therapeutic targets
  4933. Antibiotic administration exacerbates acute graft vs. host disease-induced bone marrow and spleen damage in lymphopenic mice
  4934. Effects of exercise on cellular and tissue aging
  4935. Reactive Oxygen Species and Protein Homeostasis in Skeletal Muscle Regeneration
  4936. Telomere length assessments of muscle Stem cells in rodent and human skeletal muscle sections
  4937. Not enough by half: NFAT5 haploinsufficiency in two patients with Epstein-Barr virus susceptibility
  4938. The mTOR–lysosome axis at the centre of ageing
  4939. Sirtuin 6: linking longevity with genome and epigenome stability
  4940. T cell markers recount the course of immunosenescence in healthy individuals and chronic kidney disease
  4941. Reduction of Derlin activity suppresses Notch-dependent tumours in the C. elegans germ line
  4942. Targeting the Molecular & Cellular Pillars of Human Aging with Exercise
  4943. Mechanisms of somatic transformation in inherited bone marrow failure syndromes
  4944. Graft-versus-host disease: a disorder of tissue regeneration and repair
  4945. Types and Origin of Stem Cells
  4946. The Elabela-APJ axis: a promising therapeutic target for heart failure
  4947. Age-related alterations and senescence of mesenchymal stromal cells: Implications for regenerative treatments of bones and joints
  4948. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells
  4949. The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling
  4950. The potential role of mesenchymal Stem cells in modulating antiageing process
  4951. Extracellular Vesicles in Pulmonary Fibrosis Models and Biological Fluids of Interstitial Lung Disease Patients: A Scoping Review
  4952. Stem cells of aquatic invertebrates as an advanced tool for assessing ecotoxicological impacts
  4953. Potential of mesenchymal Stem cells in the rejuvenation of the aging immune syStem
  4954. Microenvironmental control of cell fate decisions in mammary gland development and cancer
  4955. RUNX1 gene expression in Egyptian acute myeloid leukemia patients: may it have therapeutic implications?
  4956. In vivo live imaging of postnatal neural Stem cells
  4957. Who is Responsible for Aging: Life Style or Genetics or Both
  4958. Circulating Pro-vascular Progenitor cell Content in Type 2 Diabetes
  4959. Thermophiles reveal the clues to longevity: precise protein synthesis
  4960. The modification of cancer risk by chemicals
  4961. Mild High Concentrations of Boric Acid Repress Leaf Formation and Primary Root Growth in Arabidopsis Seedlings While Showing Anti-apoptotic Effects in a Mutant …
  4962. Oxidative stress and Aging: changes in important cell signaling pathways
  4963. Inflammation, Ageing and Diseases of the Lung: Potential therapeutic strategies from shared biological pathways
  4964. Chronic lung diseases: prospects for regeneration and repair
  4965. Aging biomarkers-A global view
  4966. Bcl-xL as a Modulator of Senescence and Aging
  4967. Myeloid cell -mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of …
  4968. Clonal hematopoiesis associated with epigenetic aging and clinical outcomes
  4969. Beyond genomics—technological advances improving the molecular characterization and precision treatment of heart failure
  4970. Autophagy and the hallmarks of aging
  4971. Chromatin alterations in the aging lung change progenitor cell activity
  4972. The killifish visual syStem as an in vivo model to study brain aging and rejuvenation
  4973. Gradient biomimetic platforms for neurogenesis studies
  4974. Implication of ferroptosis in aging
  4975. Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities
  4976. The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling
  4977. Therapeutic potential of adipose tissue‐derivatives in modern dermatology
  4978. CXCL2 Impairs Functions of Bone Marrow Mesenchymal Stem Cells and Can Serve as a Serum Marker in High-Fat Diet-Fed Rats
  4979. Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics
  4980. Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases
  4981. Aging impairs the essential contributions of non‐glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeri
  4982. Senescence under appraisal: hopes and challenges revisited
  4983. In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation
  4984. Evidence of the cellular senescence stress response in mitotically active brain cells—implications for cancer and neurodegeneration
  4985. Role of Nrf2 in cell senescence regulation
  4986. Ophthalmic findings and a novel CTC1 gene mutation in coats plus syndrome: a case report
  4987. Getting blood out of a stone: Identification and management of patients with poor hematopoietic cell mobilization
  4988. Oxidative stress and ROS-mediated signaling in leukemia: Novel promising perspectives to eradicate chemoresistant cells in myeloid leukemia
  4989. tRNA-derived fragments as New Hallmarks of Aging and Age-related Diseases
  4990. Association of the age at menarche with site-specific cancer risks in pooled data from nine cohorts
  4991. TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters
  4992. Spatiotemporal Extracellular Matrix Modeling for in Situ cell Niche Studies
  4993. Plasmonic fusion between fibroblasts and skeletal muscle cells for skeletal muscle regeneration
  4994. Epigenetic age prediction
  4995. mTORC1‐mediated amino acid signaling is critical for cell fate determination under transplant‐induced stress
  4996. Potential Application of Low-Intensity Pulsed Ultrasound in Delaying Aging for Mice
  4997. Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease
  4998. Analyzing signaling activity and function in hematopoietic cells
  4999. cell Culture Studies: A Promising Approach to the Metabolomic Study of Human Aging
  5000. Intermittent and periodic fasting, longevity and disease
  5001. New Markers of Disease Progression in Myelofibrosis
  5002. p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model
  5003. Principles of the Molecular and Cellular Mechanisms of Aging
  5004. Candidate gene modifiers of dystrophinopathy identified by the uniform application of genome-wide datasets to novel GWAS-identified loci
  5005. TRF2 rescues pathogenic phenotypes in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs
  5006. Epigenetic Regulation of Gut Microbial Dysbiosis
  5007. Accelerated Aging as a Paradigm to Understand the Late Effects of Cancer Therapies
  5008. DNA-and telomere-damage does not limit lifespan: evidence from rapamycin
  5009. Causal Effect of Visceral Adipose Tissue Accumulation on the Human Longevity: A Mendelian Randomization Study
  5010. The Impact of Vitamin C on Different SyStem Models of Werner Syndrome
  5011. foxm1 Modulates cell Non-Autonomous Response in Zebrafish Skeletal Muscle Homeostasis
  5012. Role of muscle Stem cells in sarcopenia
  5013. The physical frailty syndrome as a transition from homeostatic symphony to cacophony
  5014. Impact of Chaperone-Mediated Autophagy in Brain Aging: Neurodegenerative Diseases and Glioblastoma
  5015. Molecular mechanisms of postintensive care syndrome
  5016. Remodeling of the Bone Marrow Stromal Microenvironment During Pathogenic Infections
  5017. Cellular senescence and aging in bone
  5018. Role of autophagy in dysregulation of oral mucosal homeostasis
  5019. The dynamic changes of Nrf2 mediated oxidative stress, DNA damage and base excision repair in testis of rats during aging
  5020. Hematopoietic Stem cells in wound healing response
  5021. The role of muscle Stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury
  5022. Heterochromatin and Polycomb as regulators of haematopoiesis
  5023. Biomarkers for Physical Frailty and Sarcopenia: A “Two‐Body Problem”
  5024. Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade
  5025. Curcumin as prospective anti-aging natural compound: Focus on brain
  5026. The effect of Age and Frailty on clinical outcomes after surgery for Degenerative Cervical Myelopathy
  5027. Cellular Senescence and Senescence-Associated Secretory Phenotype Drive Multipotent Cardiac Stem/Progenitor cell Dysfunction in Human Diabetic …
  5028. Ubiquitin Ligases Involved in progeroid Syndromes and age-associated pathologies
  5029. From development to aging: the path to cellular senescence
  5030. Fibroageing: An ageing pathological feature driven by dysregulated extracellular matrix-cell mechanobiology
  5031. Premature aging disorders: A clinical and genetic compendium
  5032. Therapeutic cell reconditioning
  5033. Nicotinamide Phosphoribosyltransferase as a key molecule of the aging/senescence process
  5034. Evolving roles of muscle-resident fibro-adipogenic progenitors in health, regeneration, neuromuscular disorders, and aging
  5035. Mechanisms of Ataxia Telangiectasia Mutated (ATM) Control in the DNA Damage Response to Oxidative Stress, Epigenetic Regulation, and Persistent Innate Immune …
  5036. IDH1 gene mutation activates Smad signaling molecules to regulate the expression levels of cell cycle and biological rhythm genes in human glioma U87‑MG …
  5037. Nuclear DEK preserves hematopoietic Stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis
  5038. Aging and age‐related diseases: from mechanisms to therapeutic strategies
  5039. Chi-miR-130b-3p regulates Inner Mongolia cashmere goat skin hair follicles in fetuses by targeting Wnt family member 10A
  5040. Microsatellite Instability Assessment by Immunohistochemistry in Acute Myeloid Leukemia: A Reappraisal and Review of the Literature
  5041. cell cycle checkpoint control in response to DNA damage by environmental stresses
  5042. p53 activation in genetic disorders: different routes to the same destination
  5043. A gerophysiology perspective on healthy ageing
  5044. Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures
  5045. CAR-HEMATOTOX: a model for CAR T-cell –related hematologic toxicity in relapsed/refractory large B-cell lymphoma
  5046. Therapy-induced senescence: opportunities to improve anticancer therapy
  5047. Age-specific oncogenic pathways in head and neck squamous cell carcinoma-are elderly a different subcategory?
  5048. FACULTY OF MEDICINE DEPARTMENT OF BIOLOGY
  5049. Extracellular Vesicles: Footprints of environmental exposures in the aging process?
  5050. Dynamic Aging: Channeled through Microenvironment
  5051. Ageing mechanisms that contribute to tissue remodeling in lung disease
  5052. Functional decline among older cancer survivors in the Baltimore longitudinal study of aging
  5053. Chromosome instability, aging and brain diseases
  5054. Frontal fibrosing alopecia
  5055. Parathyroid hormone signaling in mature osteoblasts/osteocytes protects mice from age-related bone loss
  5056. MiR-18a-3p improves cartilage matrix remodeling and inhibits inflammation in osteoarthritis by suppressing PDP1
  5057. Assessment of outcomes after stopping tyrosine kinase inhibitors among patients with chronic myeloid leukemia: a nonrandomized clinical trial
  5058. Targeting alternative splicing for reversal of cellular senescence in the context of aesthetic aging
  5059. Telomeres in interstitial lung disease
  5060. Mini-review: The anti-aging effects of lithium in bipolar disorder
  5061. High Expression of VAV Gene Family Predicts Poor Prognosis of Acute Myeloid Leukemia
  5062. The interplay of the genetic architecture, aging, and environmental factors in the pathogenesis of idiopathic pulmonary fibrosis
  5063. GH and senescence: a new understanding of adult GH action
  5064. Autophagy in healthy aging and disease
  5065. Targeting aging: lessons learned from immunometabolism and cellular senescence
  5066. Efficient production of human neutrophils from iPSCs that prevent murine lethal infection with immune cell recruitment
  5067. Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases
  5068. Voluntary Aerobic Exercise Attenuates Frailty in a Sex-Specific Manner in Older Male and Female C67Bl/6 Mice
  5069. Wnt-induced, TRP53-mediated cell Cycle Arrest of Precursors Underlies Interstitial cell of Cajal Depletion During Aging
  5070. Neutrophils modulate fibrogenesis in chronic pulmonary diseases
  5071. The Arabidopsis MYB5 transcription factor interacts with CASEIN KINASE2 BETA3 subunit in a yeast two-hybrid syStem
  5072. Frailty: Past, present, and future?
  5073. Senescence in Bacteria and Its Underlying Mechanisms
  5074. Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock
  5075. Duchenne’s muscular dystrophy involves a defective transsulfuration pathway activity
  5076. Pannexin 1 regulates skeletal muscle regeneration by promoting bleb-based myoblast migration and fusion through a novel lipid based signaling mechanism
  5077. ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/β-Catenin
  5078. Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?
  5079. Longitudinal assessment of FEV1 change following autologous cellular therapy
  5080. Pathobiology of aging: An introduction to age-related diseases
  5081. Treatment of small cell lung cancer: recent advances
  5082. PML/RARα Fusion Gene and Response to Retinoic Acid and Arsenic Trioxide Treatment
  5083. miRNA and lncRNA Expression Networks Modulate cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells
  5084. High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging
  5085. Integrated bioinformatics analysis to identify abnormal methylated differentially expressed genes for predicting prognosis of human colon cancer
  5086. Plasma microRNAs are associated with domain-specific cognitive function in people with HIV
  5087. Therapeutic vulnerabilities of transcription factors in AML
  5088. In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation
  5089. Centenarians as models of healthy aging: Example of REST
  5090. Age and/or postmenopausal status as risk factors for pelvic organ prolapse development: syStematic review with meta-analysis
  5091. Targeting Nrf2 for the treatment of Duchenne muscular dystrophy
  5092. Pulmonary Pathology of End-Stage COVID-19 Disease in Explanted Lungs and Outcomes After Lung Transplantation
  5093. MEIS1 in Hematopoiesis and Cancer. How MEIS1-PBX Interaction Can Be Used in Therapy
  5094. Cellular senescence in lung fibrosis
  5095. Bone aging, cellular senescence, and osteoporosis
  5096. Wnt signaling is deranged in asthmatic bronchial epithelium and fibroblasts
  5097. Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care
  5098. Identification of a Sesquiterpene Lactone from Arctium lappa Leaves with Antioxidant Activity in Primary Human Muscle Cells
  5099. Autophagy on the road to longevity and aging
  5100. Mechanisms of longevity extension and healthy aging by over-expression of cytochrome b5 reductase 3
  5101. Cancer and frailty in older adults: A nested case-control study of the Mexican health and aging study
  5102. Cyclin-Dependent Kinase Inhibitors in Hematological Malignancies—Current Understanding,(Pre-) Clinical Application and Promising Approaches
  5103. Sex‐specific aging in animals: Perspective and future directions
  5104. Senescence mechanisms and targets in the heart
  5105. The 90 plus: longevity and COVID-19 survival
  5106. miRNA and lncRNA Expression Networks Modulate cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells. Genes 2022, 13, 208
  5107. Current status and future directions of clinical applications using iPS cells—focus on Japan
  5108. Toll-Like Receptor Signaling in the Establishment and Function of the Immune SyStem
  5109. Epigenetics in a spectrum of myeloid diseases and its exploitation for therapy
  5110. Role of mismatch repair in aging
  5111. Lung aging and senescence in health and disease
  5112. Targeting Cellular Senescence with Senotherapeutics: Senolytics and Senomorphics
  5113. Methyltransferases in the Pathogenesis of Keratinocyte Cancers
  5114. Thrombopoietic effects of CCAAT/enhancer-binding protein β on the early-stage differentiation of megakaryocytes
  5115. The acceleration of ageing in older patients with cancer
  5116. Lack of spinal neuropeptide Y is involved in mechanical itch in aged mice
  5117. Sarcopenia–Molecular mechanisms and open questions
  5118. PNKP is required for maintaining the integrity of progenitor cell populations in adult mice
  5119. New intervention strategies in aging and cancer based on gene edition and proteostasis modulation
  5120. Primary cilia and ciliary signaling pathways in aging and age-related brain disorders
  5121. Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of …
  5122. Biguanides drugs: Past success stories and promising future for drug discovery
  5123. Advances in understanding of the role of lipid metabolism in aging
  5124. When things go wrong: exploring possible mechanisms driving the progressive fibrosis phenotype in interstitial lung diseases
  5125. Brain-protective mechanisms of transcription factor NRF2: toward a common strategy for neurodegenerative diseases
  5126. EnvIRONmental Aspects in Myelodysplastic Syndrome
  5127. Hallmarks of Cancers: Primary Antibody Deficiency Versus Other Inborn Errors of Immunity
  5128. Pol α-primase dependent nuclear localization of the mammalian CST complex
  5129. Activatable senoprobes and senolytics: Novel strategies to detect and target senescent cells
  5130. Mesenchymal Stromal Cells for the Treatment of Interstitial Lung Disease in Children: A Look from Pediatric and Pediatric Surgeon Viewpoints
  5131. Senescence and apoptosis: architects of mammalian development
  5132. The role of exosomal non‐coding RNAs in aging‐related diseases
  5133. Expression and prognostic value of transcription-associated cyclin-dependent kinases in human breast cancer
  5134. Effect of rapamycin on aging and age-related diseases—past and future
  5135. Exosomes and micro-RNAs in aging process
  5136. miR-24: Prdx6 interactions regulate oxidative stress and viability of myogenic progenitors during ageing
  5137. Aging of the Retina: Molecular and Metabolic Turbulences and Potential Interventions
  5138. Complex Interactions in Regulation of Haematopoiesis—An Unexplored Iron Mine
  5139. A rapidly aging world in the 21st century: Hopes from glycomics and unraveling the biomarkers of aging with the sugar code
  5140. DNA methylation-based age clocks: from age prediction to age reversion
  5141. AGEs/RAGE blockade downregulates Endothenin-1 (ET-1), mitigating Human Umbilical Vein Endothelial Cells (HUVEC) injury in deep vein thrombosis (DVT)
  5142. GATA2 deficiency syndrome: A decade of discovery
  5143. Skin Blistering and Collagens: From Bench to Therapies
  5144. Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis
  5145. Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers
  5146. Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging
  5147. Aging and its treatment with vitamin C: a comprehensive mechanistic review
  5148. A Novel Role for BRIP1/FANCJ in Neuronal Cells Health and in Resolving Oxidative Stress-Induced DNA Lesions
  5149. Telomerase as a therapeutic target in cardiovascular disease
  5150. Reactive oxygen species modulators in pulmonary medicine
  5151. Precision redox: the key for antioxidant pharmacology
  5152. Cellular aging in vitro recapitulates multi-tissue epigenetic aging in vivo
  5153. A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s disease
  5154. Senescent cells as promising targets to tackle age-related diseases
  5155. The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle
  5156. Foundations in Biogerontology
  5157. Ageing, Age-Related Cardiovascular Risk and the Beneficial Role of Natural Components Intake
  5158. Cyclin‐dependent kinase 7 is essential for spermatogenesis by regulating retinoic acid signaling pathways and the STAT3 molecular pathway
  5159. The dark side of daylight: photoaging and the tumor microenvironment in melanoma progression
  5160. Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease
  5161. Gut barrier disruption and chronic disease
  5162. MicroRNA-29a mitigates osteoblast senescence and counteracts bone loss through oxidation resistance-1 control of FoxO3 methylation
  5163. Cellular remodeling in response to nutrient exhaustion : From membrane contact sites to autophagy
  5164. Epigenetics of aging and aging-associated diseases
  5165. Anti-oxidant, anti-inflammatory and anti-fibrosis effects of ganoderic acid A on carbon tetrachloride induced nephrotoxicity by regulating the Trx/TrxR and JAK/ROCK …
  5166. Autophagy in metabolic disease and ageing
  5167. Idiopathic pulmonary fibrosis beyond the lung: Understanding disease mechanisms to improve diagnosis and management
  5168. Role of stress granules in modulating senescence and promoting cancer progression: Special emphasis on glioma
  5169. Age-Associated Induction of Senescent Transcriptional Programs in Human Glial Progenitor Cells
  5170. Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies
  5171. Key signaling pathways in aging and potential interventions for healthy aging
  5172. Single-cell Transcriptomic Profiling of the Hypothalamic Median Eminence during Aging
  5173. Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in mice
  5174. The Role of NAD+ in Rejuvenating Human Body
  5175. Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing
  5176. The role of Rapamycin in healthspan extension via the delay of organ aging
  5177. Revisiting the human dental follicle: From tooth development to its association with unerupted or impacted teeth and pathological changes
  5178. An example of functional integration and application of diversity, inequities, and social determinants of health in an applied physiology course
  5179. Modulation of fracture healing by the transient accumulation of senescent cells
  5180. Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline
  5181. Mulberry polyphenol extracts attenuated senescence through inhibition of Ras/ERK via promoting Ras degradation in VSMC
  5182. CISD2 maintains cellular homeostasis
  5183. Signaling pathways and effectors of aging.
  5184. Antiaging Effects of Vicatia thibetica de Boiss Root Extract on Caenorhabditis elegans and Doxorubicin-Induced Premature Aging in Adult Mice
  5185. Age‐related changes in metabolites in young donor livers and old recipient sera after liver transplantation from young to old rats
  5186. MicroRNA-34a: the bad guy in age-related vascular diseases
  5187. Effects of Aging on Metabolic Characteristics of Human B Cells
  5188. Synthetic mRNAs; Their Analogue Caps and Contribution to Disease
  5189. An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
  5190. Alterations of the MDM2 C-terminus differentially impact its function in vivo
  5191. Can you be biologically younger than your chronological age? An overview of biological ageing
  5192. OB-Folds and Genome Maintenance: Targeting Protein–DNA Interactions for Cancer Therapy
  5193. Discovery of a novel CDK7 inhibitor YPN-005 in small cell lung cancer
  5194. Tissue-specific landscape of metabolic dysregulation during ageing
  5195. Late Effects of Therapy of Acute Lymphoblastic Leukemia
  5196. Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age
  5197. From genoprotection to rejuvenation
  5198. Rodent studies of developmental programming and ageing mechanisms: special issue: in utero and early life programming of ageing and disease
  5199. Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration
  5200. Characterising Daphnia magna as a model for ageing research
  5201. Chemical and biological basis for development of novel radioprotective drugs for cancer therapy
  5202. Exploring the effects of CDK7 inhibition by YKL-5-124 on the molecular mechanisms and the ways it triggers cytokines production in Small cell Lung Cancer in vitro
  5203. Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation
  5204. Role of aging in modulating early oral lesions
  5205. Autophagy and Aging: Roles in Skeletal Muscle, Eye, Brain and Hepatic Tissue
  5206. How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life Span
  5207. Accelerating the Mdx Heart Histo-Pathology through Physical Exercise
  5208. Biogenesis, Functions, and Cancer Relationships of a Specific Circular RNA: CircFoxo3
  5209. Methylation of dual-specificity phosphatase 4 controls cell differentiation
  5210. Exercise, epigenetics, and aging
  5211. Telomere Targeting Approaches in Cancer: Over the Length Maintenance.
  5212. Microplastics: a threat for male fertility
  5213. Origins and evolution of extreme life span in Pacific Ocean rockfishes
  5214. Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle
  5215. Biological aging in schizophrenia and psychosis severity: DNA methylation analysis
  5216. PD-L1 expression in patients with idiopathic pulmonary fibrosis
  5217. Unravelling the mechanisms driving multimorbidity in COPD to develop holistic approaches to patient-centred care
  5218. Role of Transcription Factor Atf3 in the Bone Marrow Microenvironment During Breast Cancer Development: A Response Marker or an Active Player of …
  5219. The CBX proteins in hematopoiesis and leukemia and the therapeutic potential of CBX7
  5220. Strategies to prevent or remediate cancer and treatment-related aging
  5221. Progesterone Suppresses Cholesterol Esterification in APP/PS1 mice and a cell model of Alzheimer’s Disease
  5222. Frailty and pain, human studies and animal models
  5223. CST in maintaining genome stability: Beyond telomeres
  5224. Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5
  5225. Dismantling anti-ageing medicine: why age-relatedness of cardiovascular disease is proof of robustness rather than of ageing-associated vulnerability
  5226. WNT Signalling in Lung Physiology and Pathology
  5227. Molecular profiling of intrabony defects’ gingival crevicular fluid
  5228. Cellular senescence and the skeleton: pathophysiology and therapeutic implications
  5229. Connecting vascular aging and frailty in Alzheimer’s disease
  5230. Changes in Chromatin Organization Eradicate Cellular Stress Resilience to UVA/B Light and Induce Premature Aging
  5231. Stress-induced senescence as a forme fruste of chronic kidney disease—A case for failed regeneration
  5232. The hoverfly and the wasp: A critique of the hallmarks of aging as a paradigm
  5233. Senotherapeutics: Targeting senescent cells for the main age-related diseases
  5234. Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19
  5235. Aging impairs the essential contributions of non-glial progenitors to neurorepair in the dorsal telencephalon of the Killifish N. furzeri
  5236. Histone methylation related therapeutic challenge in cardiovascular diseases
  5237. Applying the NIA Health Disparities Research Framework to Identify Needs and Opportunities in Chronic Musculoskeletal Pain Research
  5238. KR-31831 improves survival and protects hematopoietic cells and radiosensitive tissues against radiation-induced injuries in mice
  5239. The Role of Extracellular Vesicles as a Shared Disease Mechanism Contributing to Multimorbidity in Patients With COPD.
  5240. Nucleotide‐binding domain and leucine‐rich‐repeat‐containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of …
  5241. The Aging Liver: Redox Biology and Liver Regeneration
  5242. Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex
  5243. A multi‐level assessment of the bidirectional relationship between aging and the circadian clock
  5244. Novel strategies for healthy brain aging
  5245. Klotho and aging phenotypes
  5246. Human CST (CTC1-STN1-TEN1) Promotes TopBP1 Stability and CHK1 Phosphorylation in Response to Telomere Dysfunction and Global Replication Stress
  5247. p53–GSDME Elevation: A Path for CDK7 Inhibition to Suppress Breast Cancer cell Survival
  5248. Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology
  5249. Defective autophagy and mitophagy in aging and Alzheimer’s disease
  5250. Retrotransposons as a Source of DNA Damage in Neurodegeneration
  5251. Dact1 is expressed during chicken and mouse skeletal myogenesis and modulated in human muscle diseases
  5252. Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1
  5253. Research Advances in the Mutual Mechanisms Regulating Response of Plant Roots to Phosphate Deficiency and Aluminum Toxicity
  5254. Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms
  5255. Interconnections between inflammageing and immunosenescence during ageing
  5256. Sexual dimorphism in liver cell cycle and senescence signalling pathways in young and old rats
  5257. Tissue-engineered skeletal muscle models to study muscle function, plasticity, and disease
  5258. Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release
  5259. Frailty syndrome: A target for functional nutrients?
  5260. The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function
  5261. Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy
  5262. Loss of full-length dystrophin expression results in major cell -autonomous abnormalities in proliferating myoblasts
  5263. The old guard: Age-related changes in microglia and their consequences
  5264. Obesity and aging: Molecular mechanisms and therapeutic approaches
  5265. Anthracycline chemotherapy‐mediated vascular dysfunction as a model of accelerated vascular aging
  5266. A machine learning predictive model of in-hospital mortality in patients with sepsis complicated by anemia: a retrospective study based on the MIMIC-III …
  5267. Longevity, cellular senescence and the gut microbiome: lessons to be learned from crocodiles
  5268. Regulation and metabolic functions of mTORC1 and mTORC2
  5269. Oncogenic dysregulation of pre‐mRNA processing by protein kinases: challenges and therapeutic opportunities
  5270. Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D-and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth
  5271. Natural products as geroprotectors: An autophagy perspective
  5272. Donor factors and risk of primary graft dysfunction and mortality post lung transplantation: A proposed conceptual framework
  5273. Sodium rutin extends lifespan and health span in mice including positive impacts on liver health
  5274. Comparing anti–aging hallmark activities of Metformin and Nano-PSO in a mouse model of genetic Creutzfeldt-Jakob Disease
  5275. Cytotoxicity in fibroblasts from young and elderly donors from two mouthwashes used to prevent the spread of SARS-CoV-2
  5276. Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study
  5277. H3K4 Methylation in Aging and Metabolism
  5278. Competitive endogenous RNA network and pathway-based analysis of LncRNA single-nucleotide polymorphism in myasthenia gravis
  5279. Aging biomarkers and the brain
  5280. The role of protein persulfidation in brain aging and neurodegeneration
  5281. Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells
  5282. A single short reprogramming early in life improves fitness and increases lifespan in old age
  5283. Injury and regeneration in renal aging
  5284. How does the environment affect human ageing? An interdisciplinary review
  5285. Hematological consequences of malaria in mice previously treated for visceral leishmaniasis
  5286. Reconstitution of a telomeric replicon organized by CST
  5287. A Role of Stress Sensor Nrf2 in Stimulating Thermogenesis and Energy Expenditure
  5288. Update in chronic obstructive pulmonary disease 2020
  5289. S‐allylcysteine Ameliorates Aging Features Via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice
  5290. Extracellular vesicles as novel diagnostic and prognostic biomarkers for Parkinson’s disease
  5291. The poorly conducted orchestra of steroid hormones, oxidative stress and inflammation in frailty needs a maestro: Regular physical exercise
  5292. Endothelial dysfunction in COPD: a syStematic review and meta-analysis of studies using different functional assessment methods
  5293. Cellular senescence—an aging hallmark in chronic obstructive pulmonary disease pathogenesis
  5294. Why brain functions may deteriorate with aging: a thermodynamic evaluation
  5295. Tendon Extracellular Matrix Assembly, Maintenance and Dysregulation Throughout Life
  5296. circEVI5 acts as a miR-4793-3p sponge to suppress the proliferation of gastric cancer
  5297. Revista de Investigación Clínica-Clinical and Translational Investigation-: Editors’ Choices 6 Years Later
  5298. Telomere maintenance and genome stability
  5299. MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
  5300. The plasticity of ageing and the rediscovery of ground-state prevention
  5301. Oxidative stress, antioxidants, hormesis and calorie restriction: The current perspective in the biology of aging
  5302. Sex differences in biological aging with a focus on human studies
  5303. The impact of the diet in adult C57BI/6J mice pancreas function with age
  5304. Supplemental Material and Methods
  5305. The Intrinsically Disordered Region in the Human STN1 OB-Fold Domain Is Important for Protecting Genome Stability
  5306. Developing and pilot testing a frailty-focused education and communication training workshop
  5307. 8 Identifying Life-History Events in Dental Cementum: A Literature
  5308. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation …
  5309. p62 works as a hub modulation in the ageing process
  5310. Machine learning-based predictions of dietary restriction associations across ageing-related genes
  5311. MicroRNAs as Factors in Bidirectional Crosstalk Between Mitochondria and the Nucleus During Cellular Senescence
  5312. Aging Justice: Health Justice Extended
  5313. Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres
  5314. Redox Dynamic Homeostasis and Aging
  5315. Understanding the Potential Role of Sirtuin 2 on Aging: Consequences of SIRT2. 3 Overexpression in Senescence
  5316. Rapid changes of miRNAs-20,-30,− 410,− 515,− 134, and− 183 and telomerase with psychological activity: A one year study on the relaxation response and …
  5317. ADAM10 as a biomarker for Alzheimer’s disease
  5318. Alternative animal models of aging research
  5319. The biological relevance of pigment epithelium-derived factor on the path from aging to age-related disease
  5320. Yeast as a model organism for aging research
  5321. Mutagenesis screen uncovers lifespan extension through integrated stress response inhibition without reduced mRNA translation
  5322. A critical review of the mechanisms involved in the occurrence of growth-related abnormalities affecting broiler chicken breast muscles
  5323. Transcription-Replication Collisions—A Series of Unfortunate Events
  5324. Tenascin-C: Friend or Foe in Lung Aging?
  5325. Single cell transcriptomic mapping of cell state identities in lung aging, injury and repair
  5326. Characterization of Stress Responses in a Drosophila Model of Werner Syndrome
  5327. Aging in psoriasis vulgaris: female patients are epigenetically older than healthy controls
  5328. The ABCA1-efferocytosis axis: a new strategy to protect against atherosclerosis
  5329. Identification of Genetic Signature Associated With Aging in Pulmonary Fibrosis
  5330. Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as …
  5331. Dysbiosis, malnutrition and enhanced gut-lung axis contribute to age-related respiratory diseases
  5332. The interplay between mitochondrial morphology and myomitokines in aging sarcopenia
  5333. The Incidence and Predictors of Solid-and Hematological Malignancies in Patients with Giant cell Arteritis: A Large Real-World Database Study
  5334. Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome
  5335. Ninjin’yoeito modulates feeding and activity under negative energy balance conditions via the NPY syStem
  5336. REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons
  5337. Transposable elements as new players in neurodegenerative diseases
  5338. The pro-fibrotic and senescence phenotype of old lung fibroblasts is reversed or ameliorated by genetic and pharmacological manipulation of Slc7a11 expression
  5339. Decoding and rejuvenating human ageing genomes: Lessons from mosaic chromosomal alterations
  5340. Non-coding RNA basis of muscle atrophy
  5341. Lifetime impact of cow’s milk on overactivation of mTORC1: From fetal to childhood overgrowth, acne, diabetes, cancers, and neurodegeneration
  5342. Pyroptosis, and its Role in Central Nervous SyStem Disease
  5343. Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer’s Disease
  5344. Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy
  5345. Autophagy in Aging and Oxidative Stress
  5346. Prodromal Parkinson disease subtypes—key to understanding heterogeneity
  5347. Hematological consequences of malaria infection in mic e previously treated for visceral leishmaniasis [version 1; peer
  5348. Mitochondria and Antibiotics: For Good or for Evil?
  5349. Novel Natural Inhibitors Targeting Enhancer of Zeste Homolog 2: A Comprehensive Structural Biology Research
  5350. Long‐Lived Cells and Long‐Lived Proteins in the Human Body
  5351. Hematological consequences of malaria in mice previously treated for visceral leishmaniasis [version 2; peer review: 2 approved]
  5352. Obesity definition, diagnosis, bias, standard operating procedures (SOPs), and telehealth: An Obesity Medicine Association (OMA) Clinical Practice Statement …
  5353. Longevity pathways are associated with human ovarian ageing
  5354. Exploration of molecular mechanism of the retina aging
  5355. Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials in Caenorhabditis elegans
  5356. CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium
  5357. G. sinense and P. notoginseng Extracts Improve Healthspan of Aging Flies and Provide Protection in A Huntington Disease Model
  5358. The role of rice SOG1 and SOG1-like in DNA damage response
  5359. Translational research in the fastest-growing population: older adults
  5360. Targeting inflammation by anthocyanins as the novel therapeutic potential for chronic diseases: An update
  5361. MG132 Induces Progerin Clearance and Improves Disease Phenotypes in HGPS-like Patients’ Cells
  5362. Mitochondria and Antibiotics: For Good or for Evil?
  5363. The Reactive Species Interactome in the Brain
  5364. Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism
  5365. Chemical modulation of gasdermin-mediated pyroptosis and therapeutic potential
  5366. Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function
  5367. Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis
  5368. Priming with growth regulators stimulates germination, growth and physiological characteristics of Indian squash (Praecitrullus fistulosus)
  5369. Biomarkers shared by frailty and sarcopenia in older adults: A syStematic review and meta-analysis
  5370. Osteoporosis and bone loss
  5371. Case studies discussing the pathology, immunogenicity, and proposed mechanism of toxicity of an inhaled anti-tgfβ humanized fab antibody in non-human primates …
  5372. Cellular senescence in brain aging
  5373. Identification source and human health risk assessment of potentially toxic metal in soil samples around karst watershed of Pangkajene, Indonesia
  5374. The Synergy of Adenosine and Ibrutinib on Platelet Aggregation in Chronic Lymphocytic Leukemia
  5375. Study of longitudinal aging in mice: Presentation of experimental techniques
  5376. Proteostasis and Skin Aging
  5377. Proteomics and epidemiological models of human aging
  5378. Bridging the gap: A geroscience primer for neuroscientists with potential collaborative applications
  5379. Collagen biosynthesis, processing, and maturation in lung ageing
  5380. MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway
  5381. Effects of aging on gene expression levels of inflammatory, cytoskeletal and microglial markers in the brain using the zebrafish (Danio Rerio) model organism
  5382. Vacuolar transporter Mnr2 safeguards organellar integrity in aged cells
  5383. Transcriptomic analysis of mdx mouse muscles reveals a signature of early human Duchenne muscular dystrophy
  5384. Single-cell Transcriptomics Reveals the Expression of Aging-and Senescence-Associated Genes in Distinct Cancer cell Populations
  5385. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
  5386. The Role of Ageing and Parenchymal Senescence on Macrophage Function and Fibrosis
  5387. Neuropeptides: Roles and activities as metal chelators in neurodegenerative diseases
  5388. Interferon-γ-producing CD4+ T cells drive monocyte activation in the bone marrow during experimental Leishmania donovani infection
  5389. Therapeutic Ultrasound as a Treatment Modality for Physiological and Pathological Ageing Including Alzheimer’s Disease
  5390. Proper control of R‐loop homeostasis is required for maintenance of gene expression and neuronal function during aging
  5391. Olive oil consumption is associated with lower frailty risk: a prospective cohort study of community-dwelling older adults
  5392. Physical performance in older adults: Association with glucose regulation and telomere length
  5393. Manipulating the exposome to enable better ageing
  5394. Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence
  5395. MiR-29a Increase in Aging May Function as a Compensatory Mechanism Against Cardiac Fibrosis Through SERPINH1 Downregulation
  5396. Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
  5397. The Role of Immune Cells in Oxi-Inflamm-Aging
  5398. The Roles of Arid2 and Arid1b in Normal and Malignant Hematopoiesis
  5399. Mitochondria and Antibiotics: For Good or for Evil? Biomolecules 2021, 11, 1050
  5400. Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of SyStemic Juvenile Idiopathic Arthritis
  5401. Reproductive suicide: similar mechanisms of aging in C. elegans and Pacific salmon
  5402. A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease
  5403. Probiotics: Emerging functional ingredients for healthy aging and age-related diseases
  5404. Cyclin-Dependent Kinases and CTD Phosphatases in cell Cycle Transcriptional Control: Conservation across Eukaryotic Kingdoms and Uniqueness to Plants
  5405. Machine-learning-based predictions of caloric restriction associations across ageing-related genes
  5406. The Danaid Theory of Aging.
  5407. Mitochondrial biogenesis and mitophagy
  5408. Association between elevated suPAR, a new biomarker of inflammation, and accelerated aging
  5409. Neuronal and glial region dependent changes in female mice from a model of premature aging
  5410. Mesenchymal Progenitors in the Epidural Fat and Dura Mater Participate in Tissue Homeostasis and Wound Healing
  5411. Tumor Microenvironment
  5412. Potential Roles of Sestrin2 in Alzheimer’s Disease: Antioxidation, Autophagy Promotion, and Beyond
  5413. Microalgal Lipid Extracts Have Potential to Modulate the Inflammatory Response: A Critical Review
  5414. Transcriptomic alterations in the aged brain with and without dietary and dietary-mimetic manipulations
  5415. Elementary Laboratory Assays as Biomarkers of Ageing: Support for Treatment of COVID-19?
  5416. Mitochondrial and metabolic dysfunction in ageing and age-related diseases
  5417. Crosstalk between CST and RPA regulates RAD51 activity during replication stress
  5418. Control of Expression of Key cell Cycle Enzymes Drives cell Line-Specific Functions of CDK7 in Human PDAC Cells
  5419. Metabolomic Profiles of Mice Tissues Reveals an Interplay Between Aging and Energy Metabolism
  5420. Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin
  5421. Nuclear Aurora-A kinase-induced hypoxia signaling drives dissemination and metastasis in breast cancer.
  5422. Therapeutic Exon Skipping Through a CRISPR-Guided Cytidine Deaminase Rescues Dystrophic Cardiomyopathy in Vivo
  5423. The Effect of Nutrition on Aging—A SyStematic Review Focusing on Aging-Related Biomarkers
  5424. Anti-Inflammatory properties of diet: role in healthy aging
  5425. The Effect of Long-Duration Spaceflight on DNA Methylation of Longevity-Related Genes in a One-Year Astronaut Study
  5426. Precocious hippocampal structural and functional changes in gestational protein-restricted male elderly offspring: an Alzheimer-simile disease model?
  5427. Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah−/− mdx …
  5428. Shaping the Face. Cytoprotective mechanisms, signaling pathways and cleft repair
  5429. Adverse effects of metformin from diabetes to COVID-19, cancer, neurodegenerative diseases, and aging: is VDAC1 a common target?
  5430. Low Psychological Resilience in Older Individuals: An Association with Increased Inflammation, Oxidative Stress and the Presence of Chronic Medical Conditions
  5431. Defy Aging: A Beginner’s Guide to the New Science of Longer Life and Better Health
  5432. Nuclear receptors in myocardial and cerebral ischemia—mechanisms of action and therapeutic strategies
  5433. Edible Beauty: Dermatologist’s Guide to an Anti-Ageing Diet
  5434. Severe Gestational Low-Protein Intake Impacts Hippocampal Cellularity, Tau, and Amyloid-β Levels, and Memory Performance in Male Adult Offspring: An …
  5435. Aging, cell Senescence, the Pathogenesis and Targeted Therapies of Osteoarthritis
  5436. The prognostic value of serum metabolites
  5437. Hallmarks of Testicular Aging: The Challenge of Anti-Inflammatory and Antioxidant Therapies Using Natural and/or Pharmacological Compounds to Improve the …
  5438. Assessing the Use of the sGC Stimulator BAY-747, as a Potential Treatment for Duchenne Muscular Dystrophy
  5439. Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging
  5440. Metabolomic profiling of plasma from middle-aged and advanced-age male mice reveals the metabolic abnormalities of carnitine biosynthesis in …
  5441. Silica Particle-Induced NLRP3 Inflammasome Activation and Dna Damage in Respiratory Epithelium
  5442. Redox Dysregulation in Aging and COPD: Role of NOX Enzymes and Implications for Antioxidant Strategies
  5443. Ageing, comorbidities and frailty in intensive care
  5444. Metabolomic Changes Are Predictive of Aging in Laying Hens
  5445. Telomere replication: solving multiple end replication problems
  5446. NAFLD in the Elderly
  5447. Mitochondrial Physiology and Vegetal Molecules: Therapeutic Potential of Natural Compounds on Mitochondrial Health
  5448. Effects of anti-aging interventions on intestinal microbiota
  5449. Memorable Food: Fighting Age-Related Neurodegeneration by Precision Nutrition
  5450. In silico identification of genetic and pharmacological interventions to modulate ageing
  5451. Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: a syStematic …
  5452. Characterizing Galectin and Lysosomal Rupture’s Role in Spreading Parkinson Disease Pathology
  5453. Longevity risk and capital markets: The 2019-20 update
  5454. Comparative study of protein aggregation propensity and mutation tolerance between naked mole-rat and mouse
  5455. Lifetime Impact of Cow’s Milk on Overactivation of mTORC1: From Fetal to Childhood Overgrowth, Acne
  5456. Molecular and Cellular Manifestations of Biological Aging of Cochlear Inner and Outer Hair Cells
  5457. Toward Precision Medicine: Effects of the Common VAL66met BDNF Variant in the Aging Brain and Implications for the Future of Parkinson’S Disease …
  5458. Fundamentals of Membrane Lipid Replacement: A Natural Medicine Approach to Repairing Cellular Membranes and Reducing Fatigue, Pain, and Other Symptoms …
  5459. Glycosylation biomarkers associated with age-related diseases and current methods for glycan analysis
  5460. Mitochondrial dysfunction as a driver of cellular senescence
  5461. Analysis of the Impact of Selected Vitamins Deficiencies on the Risk of Disability in Older People
  5462. Glycosylation and Aging
  5463. Influence of age on skeletal muscle hypertrophy and atrophy signaling: established paradigms and unexpected links
  5464. Understanding the Structure of Native Apolipoprotein-D Using an Integrative Structural Approach
  5465. On chaperone co-operation in temporal and spatial protein quality control
  5466. Inter-tissue convergence of gene expression and loss of cellular identity during ageing
  5467. Mediators of the cellular response to the development of obesity and metabolic disease
  5468. Potential Nutrients from Natural and Synthetic Sources Targeting Inflammaging—A Review of Literature, Clinical Data and Patents
  5469. The African turquoise killifish (Nothobranchius furzeri): biology and research applications
  5470. Biological Ages: Correlations, Genetic Determinants, and Health Outcomes
  5471. Mechanisms of host defense to influenza virus infection
  5472. The influence of sirtuin-controlled circadian rhythmicity anddiet on lifespan in the honey bee, Apis mellifera
  5473. Sex-specific regulation of metabolic health and vertebrate lifespan by AMP biosynthesis
  5474. The Science and Technology of Growing Young: An Insider’s Guide to the Breakthroughs that Will Dramatically Extend Our Lifespan… and What You Can Do …
  5475. Links between abnormal lipid metabolism and inflammation in Alzheimer’s disease
  5476. Sex Differences in Molecular Mechanisms of Cardiovascular Aging
  5477. microRNA: target interactions in tendinopathy
  5478. Genomic Instability at Single cell Resolution
  5479. Epigenetics of muscle disorders
  5480. Manipulating age-related metabolic flexibility
  5481. Immunotherapies Targeting the Amyotrophic Lateral Sclerosis-Associated Protein TDP-43
  5482. Body composition in 65+ European population: a focus on inflammatory and metabolic markers in healthy and frail
  5483. p21-Activated kinase 1 (PAK1) in aging and longevity: An overview
  5484. The Role of Yeast Shelterin Protein Cdc13 in the Stability of GAA Repeats
  5485. A Computational Analysis in a Cohort of Parkinson’s Disease Patients and Clock-Modified Colorectal Cancer Cells Reveals Common Expression Alterations in Clock …
  5486. Vitamin D3 Promotes Longevity in Caenorhabditis Elegans
  5487. Elucidating the role of histone variant H2A. J following ionizing radiation
  5488. Microglia in neuroinflammation and neurodegeneration: from understanding to therapy
  5489. ISEV Abstract Book
  5490. Ageing through Reproductive Death in Caenorhabditis elegans
  5491. Histopathological features in idiopathic pulmonary fibrosis: Interobserver variation, inorganic particulate matter and prognostic factors detected by artificial intelligence
  5492. Calorie restriction affects human nucleotide excision repair and the expression of aging-associated genes
  5493. Synaptic Senescence in Alzheimer’s Disease
  5494. Isolation and characterization of distinct populations of amyloid β aggregates using size exclusion chromatography and structure-specific antibody
  5495. Effect of Oxidative Stress on Lifespan and Cellular Survival
  5496. Protein aggregation, ageing and neurodegeneration in the emerging model Nothobranchius furzeri
  5497. Linking mitochondrial Src and hippocampal dendritic changes in Alzheimer’s disease
  5498. Myeloma escape after Stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade
  5499. Loss of Gata4 in Sertoli cells impairs the spermatogonial Stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling
  5500. T cell exhaustion characterized by compromised MHC class I and II restricted cytotoxic activity associates with acute B lymphoblastic leukemia relapse after allogeneic …
  5501. Autocrine Mfge8 signaling prevents developmental exhaustion of the adult neural Stem cell pool
  5502. Bone marrow central memory and memory Stem T-cell exhaustion in AML patients relapsing after HSCT
  5503. Correlations of programmed death 1 expression and serum IL-6 level with exhaustion of cytomegalovirus-specific T cells after allogeneic hematopoietic Stem cell …
  5504. Therapeutic melanoma vaccine with cancer Stem cell phenotype represses exhaustion and maintains antigen-specific T cell Stemness by up-regulating BCL6
  5505. … of growth hormone transgenic mice indicates that chronically elevated Igf1 level accelerates age-dependent exhaustion of pluripotent Stem cell pool: a novel …
  5506. T cell exhaustion /senescence in relapsed multiple myeloma after autologous Stem cell transplantation
  5507. … /CD200R-LSC/NK Synapse Including Leukemia Stem cell (LSC) Fraction As a Potential Therapeutic Target and Marker of NK cell exhaustion in Pediatric AML …
  5508. exhaustion of CMV specific T cells with enhanced PD-1 expression in persistent cytomegalovirus infection after allogeneic Stem cell transplantation
  5509. Genetic basis for haematopoietic Stem–cell exhaustion during ageing
  5510. Haematopoietic Stem cell exhaustion in ageing killifish
  5511. Sustained PU. 1 levels balance cell -cycle regulators to prevent exhaustion of adult hematopoietic Stem cells
  5512. … levels of reactive oxygen species and exhaustion of the quiescent CD34+ cells may operate in poor graft function after allogeneic hematopoietic Stem cell …
  5513. C/EBPβ is a critical regulator of CML Stem cell differentiation and exhaustion induced by interferon-α
  5514. Correlation of serum IL-6 level with exhaustion of cytomegalovirus-specific t cells after hematopoietic Stem cell transplantation
  5515. PF766 T cell exhaustion PROFILE (CD4+/CD28/PER+/GRA+ CD8+/CD28/PER+/GRA+) IN Stem cell TRANSPLANTATION, CMV RE ACTIVATIONS AND …
  5516. Continuous MEK inhibition by AZD6244 (ARRY-142886) results in exhaustion of the cutaneous keratinocytic Stem cell pool and resembles senescence driven skin …
  5517. Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem cell exhaustion Syndromes?
  5518. … COMMON DENOMINATOR: Mesenchymal Stem Cells From Idiopathic Pulmonary Fibrosis Patients Display Signs Of Senescence Leading To Stem cell exhaustion …
  5519. T cell exhaustion /senescence characterizes multiple myeloma relapse after autologous Stem cell transplantation: Implications for optimal timing of immunotherapy
  5520. Hematopoietic precursor cell exhaustion is a cause of proliferative defect in primitive hematopoietic Stem cells (PHSC) after chemotherapy.
  5521. Stem cell Replicative Stress and Clonal exhaustion
  5522. Clinical Grade Ex-Vivo Expansion of Granulomonocytic Cells and Progenitors Using High-Dose SCF and G-CSF without exhaustion of Stem cell Activity.
  5523. THE Stem cell COMPARTMENT OF THE BONE MARROW-ATTEMPTED exhaustion BY STIMULATION OF GRANULOPOIESIS, LYMPHOPOIESIS AND …
  5524. … of programmed death 1 expression and serum IL-6 level with exhaustion of cytomegalovirus-specific T cells after allogeneic hematopoietic Stem cell …
  5525. Loss of the cell Cycle Regulator p26INCA1 Induces exhaustion of Leukemic Stem Cells
  5526. Chronic Mycobacterium Avium Infection Leads to cell Autonomous exhaustion of Hematopoietic Stem Cells

 

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