AMPK ACTIVATORS

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  1. AMPK activation: a therapeutic target for type 2 diabetes?
  2. AMPK activators–potential therapeutics for metabolic and other diseases
  3. AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure
  4. Choreography of AMPK activation
  5. Use of cells expressing γ subunit variants to identify diverse mechanisms of AMPK activation
  6. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
  7. Effect of AMPK activation on muscle glucose metabolism in conscious rats
  8. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation
  9. A redox-dependent mechanism for regulation of AMPK activation by Thioredoxin1 during energy starvation
  10. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma
  11. Antileukemic effects of AMPK activators on BCR-ABL–expressing cells
  12. Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
  13. A small molecule AMPK activator protects the heart against ischemia–reperfusion injury
  14. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
  15. Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels
  16. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth
  17. Berberine suppresses proinflammatory responses through AMPK activation in macrophages
  18. Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation
  19. Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation
  20. Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
  21. Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart
  22. Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
  23. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
  24. Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells
  25. Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms
  26. AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney
  27. Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation
  28. Structural basis of AMPK regulation by small molecule activators
  29. Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes
  30. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
  31. AICAR, an AMPK activator, has protective effects on alcohol‐induced fatty liver in rats
  32. AMPK activation—protean potential for boosting healthspan
  33. Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle
  34. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation
  35. Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation
  36. AMP-activated protein kinase (AMPK) activators from Myristica fragrans (nutmeg) and their anti-obesity effect
  37. AMPK activation regulates neuronal structure in developing hippocampal neurons
  38. AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging
  39. AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2α in adipocytes
  40. AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity
  41. Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression
  42. Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
  43. AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm
  44. Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation
  45. Exercise-induced AMPK activation does not interfere with muscle hypertrophy in response to resistance training in men
  46. AMPK activation is fiber type specific in human skeletal muscle: effects of exercise and short-term exercise training
  47. Crosstalk between AMPK activation and angiotensin II‐induced hypertrophy in cardiomyocytes: the role of mitochondria
  48. AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes
  49. Metformin inhibits P‐glycoprotein expression via the NF‐κB pathway and CRE transcriptional activity through AMPK activation
  50. AMPK activators as a drug for diabetes, cancer and cardiovascular disease
  51. Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation
  52. A novel dual AMPK activator/mTOR inhibitor inhibits thyroid cancer cell growth
  53. Discovery and SAR development of thienopyridones: a class of small molecule AMPK activators
  54. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation
  55. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation
  56. AMPK activation ameliorates Alzheimer’s disease-like pathology and spatial memory impairment in a streptozotocin-induced Alzheimer’s disease model in rats
  57. A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells
  58. Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation
  59. Amelioration of LPS-induced inflammation response in microglia by AMPK activation
  60. SIRT3 reduces lipid accumulation via AMPK activation in human hepatic cells
  61. Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice
  62. AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway
  63. AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes
  64. Time course changes in signaling pathways and protein synthesis in C2C12 myotubes following AMPK activation by AICAR
  65. Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice
  66. AMPK activation via modulation of de novo purine biosynthesis with an inhibitor of ATIC homodimerization
  67. Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle
  68. AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 …
  69. AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast
  70. … metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activator
  71. AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity
  72. Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells from individuals with chronic fatigue syndrome
  73. AMP ed up to treat prostate cancer: novel AMPK activators emerge for cancer therapy
  74. AMPK activation by isorhamnetin protects hepatocytes against oxidative stress and mitochondrial dysfunction
  75. Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR‐induced AMPK activation
  76. Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation
  77. AMPK activation inhibits expression of proinflammatory mediators through downregulation of PI3K/p38 MAPK and NF-κB signaling in murine macrophages
  78. Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator
  79. AMPK activation enhances PPARα activity to inhibit cardiac hypertrophy via ERK1/2 MAPK signaling pathway
  80. Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress
  81. AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response
  82. AMPK activation inhibits the expression of HIF-1α induced by insulin and IGF-1
  83. Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab
  84. Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells
  85. Metformin induced AMPK activation, G0/G1 phase cell cycle arrest and the inhibition of growth of esophageal squamous cell carcinomas in vitro and in vivo
  86. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells
  87. Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition
  88. Promotion of adiponectin multimerization by emodin: a novel AMPK activator with PPARγ‐agonist activity
  89. AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation
  90. AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions
  91. Rutin increases muscle mitochondrial biogenesis with AMPK activation in high-fat diet-induced obese rats
  92. Antidiabetic effect of salvianolic acid A on diabetic animal models via AMPK activation and mitochondrial regulation
  93. Impaired muscle AMPK activation in the metabolic syndrome may attenuate improved insulin action after exercise training
  94. The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice
  95. AMPK activation can delay aging
  96. Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice
  97. A crystallized view of AMPK activation
  98. Berberine improves kidney function in diabetic mice via AMPK activation
  99. Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts
  100. Increased skeletal muscle glucose uptake by rosemary extract through AMPK activation
  101. Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition
  102. AMPK activation increases uncoupling protein‐3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions
  103. The hypotriglyceridemic effect of biotin supplementation involves increased levels of cGMP and AMPK activation
  104. Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation
  105. Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells
  106. Synthesis and structure–activity relationship of berberine analogues in LDLR up-regulation and AMPK activation
  107. Methyl succinate antagonises biguanide‐induced AMPK‐activation and death of pancreatic β‐cells through restoration of mitochondrial electron transfer
  108. Docosahexaenoic acid induces cell death in human non-small cell lung cancer cells by repressing mTOR via AMPK activation and PI3K/Akt inhibition
  109. CTRP1 protein enhances fatty acid oxidation via AMP-activated protein kinase (AMPK) activation and acetyl-CoA carboxylase (ACC) inhibition
  110. Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside
  111. Ginsenoside Rg3 reduces lipid accumulation with AMP-activated protein kinase (AMPK) activation in HepG2 cells
  112. Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation
  113. Small‑molecule COH-SR4 inhibits adipocyte differentiation via AMPK activation
  114. AMPK activation prevents prenatal stress-induced cognitive impairment: modulation of mitochondrial content and oxidative stress
  115. … crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation
  116. Prostaglandin E2 promotes endothelial differentiation from bone marrow-derived cells through AMPK activation
  117. Sestrin2–AMPK activation protects mitochondrial function against glucose deprivation-induced cytotoxicity
  118. Thiacremonone, a sulfur compound isolated from garlic, attenuates lipid accumulation partially mediated via AMPK activation in 3T3-L1 adipocytes
  119. Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice
  120. The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding
  121. Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells
  122. Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activation
  123. Sepsis and AMPK activation by AICAR differentially regulate FoxO-1,-3 and-4 mRNA in striated muscle
  124. Dieckol, a phlorotannin isolated from a brown seaweed, Ecklonia cava, inhibits adipogenesis through AMP-activated protein kinase (AMPK) activation in 3T3-L1 …
  125. AMPK activation by long chain fatty acyl analogs
  126. AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1
  127. HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication
  128. Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: The relationship to AMPK activation
  129. Protective effect of nectandrin B, a potent AMPK activator on neointima formation: inhibition of Pin1 expression through AMPK activation
  130. Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte
  131. The antidiabetic drug metformin: a pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy
  132. Crude Extracts from Lycium barbarum Suppress SREBP-1c Expression and Prevent Diet-Induced Fatty Liver through AMPK Activation
  133. The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression
  134. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis
  135. Endothelium-dependent vasorelaxation to the AMPK activator AICAR is enhanced in aorta from hypertensive rats and is NO and EDCF dependent
  136. AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction
  137. High glucose-induced oxidative stress alters estrogen effects on ERα and ERβ in human endothelial cells: reversal by AMPK activator
  138. Genome-wide inhibitory impact of the AMPK activator metformin on [kinesins, tubulins, histones, auroras and polo-like kinases] M-phase cell cycle genes in human …
  139. AMPK activation by AICAR inhibits myogenic differentiation and myostatin expression in cattle
  140. Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle
  141. Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
  142. AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators
  143. Effects of α‐AMPK knockout on exercise‐induced gene activation in mouse skeletal muscle
  144. AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys
  145. Activation of AMPK enhances neutrophil chemotaxis and bacterial killing
  146. AMPK activation by dihydrotestosterone reduces FSH-stimulated cell proliferation in rat granulosa cells by inhibiting ERK signaling pathway
  147. Anti-angiogenic effects of metformin, an AMPK activator, on human umbilical vein endothelial cells and on granulation tissue in rat
  148. Mitochondrial dysfunction represses HIF-1α protein synthesis through AMPK activation in human hepatoma HepG2 cells
  149. Early post-mortem AMP-activated protein kinase (AMPK) activation leads to phosphofructokinase-2 and-1 (PFK-2 and PFK-1) phosphorylation and the development of …
  150. Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficient ob/ob Mice
  151. Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells
  152. AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction
  153. Prevention of high-fat diet-induced muscular lipid accumulation in rats by α lipoic acid is not mediated by AMPK activation [S]
  154. The antidiabetic effect of ginsenoside Rb2 via activation of AMPK
  155. Antiangiogenic effects of N6‐isopentenyladenosine, an endogenous isoprenoid end product, mediated by AMPK activation
  156. Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism
  157. Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells
  158. … black carrots fermented with Aspergillus oryzae prevent the impairment of energy, lipid and glucose metabolism in estrogen-deficient rats by AMPK activation
  159. Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1β by suppressing AMP-activated protein kinase (AMPK) activation
  160. Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells
  161. AMP‐activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle
  162. Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2
  163. Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation
  164. Co-activation of AMPK and mTORC1 induces cytotoxicity in acute myeloid leukemia
  165. Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
  166. The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
  167. Activation of AMPK protects against hydrogen peroxide-induced osteoblast apoptosis through autophagy induction and NADPH maintenance: new implications for …
  168. Differential regulation of AMPK activation in leptin‐and creatine‐deficient mice
  169. Lessons from nature: sources and strategies for developing AMPK activators for cancer chemotherapeutics
  170. Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes
  171. The stimulatory effect of essential fatty acids on glucose uptake involves both Akt and AMPK activation in C2C12 skeletal muscle cells
  172. Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK
  173. Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction
  174. Fluorinated N, N′-diarylureas as AMPK activators
  175. Effect of AMPK activation on monocarboxylate transporter (MCT) 1 and MCT4 in denervated muscle
  176. Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism
  177. Lipoprotein internalisation induced by oncogenic AMPK activation is essential to maintain glioblastoma cell growth
  178. Activation of the prolyl‐hydroxylase oxygen‐sensing signal cascade leads to AMPK activation in cardiomyocytes
  179. Erythropoietin contributes to slow oxidative muscle fiber specification via PGC-1α and AMPK activation
  180. Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival
  181. Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells
  182. Ethanol extract of Cirsium japonicum attenuates hepatic lipid accumulation via AMPK activation in human HepG2 cells
  183. Oxidative stress improves coronary endothelial function through activation of the pro-survival kinase AMPK
  184. Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat
  185. Down-regulation of amyloid-β through AMPK activation by inhibitors of GSK-3β in SH-SY5Y and SH-SY5Y-AβPP695 cells
  186. Imiquimod-induced AMPK activation causes translation attenuation and apoptosis but not autophagy
  187. Overexpression of AMP‐metabolizing enzymes controls adenine nucleotide levels and AMPK activation in HEK293T cells
  188. A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3
  189. Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: interference of AMPK/PGC-1α pathway
  190. Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression
  191. Effects of activation of AMPK on human breast cancer cell lines with different genetic backgrounds
  192. Salidroside ameliorates insulin resistance through activation of a mitochondria‐associated AMPK/PI3K/A kt/GSK 3β pathway
  193. Proteasome inhibitors induce AMPK activation via CaMKKβ in human breast cancer cells
  194. Rutaecarpine Analogues Reduce Lipid Accumulation in Adipocytes via Inhibiting Adipogenesis/Lipogenesis with AMPK Activation and UPR Suppression
  195. AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia
  196. Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress
  197. Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction
  198. AMPK up-activation reduces motility and regulates other functions of boar spermatozoa
  199. Purinergic control of AMPK activation by ATP released through connexin 43 hemichannels–pivotal roles in hemichannel-mediated cell injury
  200. Wedelolactone regulates lipid metabolism and improves hepatic steatosis partly by AMPK activation and up-regulation of expression of PPARα/LPL and …
  201. Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of Akt
  202. Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB …
  203. AMP-activated Protein Kinase (AMPK) Activation and Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Induce Ca2+-independent Deposition of Tight …
  204. AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma
  205. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
  206. AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P …
  207. AMPK activation as a strategy for reversing the endothelial lipotoxicity underlying the increased vascular risk associated with insulin resistance syndrome
  208. Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro
  209. Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats …
  210. Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells
  211. Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo
  212. Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues
  213. In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis
  214. Salicylate improves macrophage cholesterol homeostasis via activation of Ampk
  215. Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis
  216. Green tea extract rich in epigallocatechin-3-gallate prevents fatty liver by AMPK activation via LKB1 in mice fed a high-fat diet
  217. Belinostat-induced apoptosis and growth inhibition in pancreatic cancer cells involve activation of TAK1-AMPK signaling axis
  218. Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase
  219. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK
  220. Alteration of splice site selection in the LMNA gene and inhibition of progerin production via AMPK activation
  221. High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-κB activation in vascular endothelial cells
  222. Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models
  223. Activation of AMPK inhibits pulmonary arterial smooth muscle cells proliferation
  224. Fenoterol inhibits LPS-induced AMPK activation and inflammatory cytokine production through β-arrestin-2 in THP-1 cell line
  225. Activation of AMPK and its impact on exercise capacity
  226. Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice
  227. GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury
  228. The AMPK agonist AICAR inhibits TGF-β1 induced activation of kidney myofibroblasts
  229. Activation of AMPK attenuates lipopolysaccharide-impaired integrity and function of blood–brain barrier in human brain microvascular endothelial cells
  230. Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation
  231. Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662
  232. Ginseng leaf extract prevents high fat diet-induced hyperglycemia and hyperlipidemia through AMPK activation
  233. Resveratrol inhibits cell differentiation in 3T3-L1 adipocytes via activation of AMPK
  234. AMPK Dilates Resistance Arteries via Activation of SERCA and BKCa Channels in Smooth Muscle
  235. Activation of AMPK by bitter melon triterpenoids involves CaMKKβ
  236. Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1
  237. Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells
  238. AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent …
  239. Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation
  240. The role of ATM in response to metformin treatment and activation of AMPK
  241. Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation
  242. Antiadipogenic effect of dietary apigenin through activation of AMPK in 3T3-L1 cells
  243. Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation
  244. Activation of AMP-activated protein kinase (AMPK) inhibits fatty acid synthesis in bovine mammary epithelial cells
  245. Liraglutide reduces lipogenetic signals in visceral adipose of db/db mice with AMPK activation and Akt suppression
  246. AMPK activation may suppress hepatic production of C-reactive protein by stimulating nitric oxide synthase
  247. Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition
  248. EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells
  249. … perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator …
  250. PKC-dependent human monocyte adhesion requires AMPK and Syk activation
  251. Requirement of AMPK activation for neuronal metabolic-enhancing effects of antidepressant paroxetine
  252. Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
  253. … inhibition sensitizes non–small cell lung cancer with T790M mutation to irreversible EGFR inhibitors via translational suppression of mcl-1 by AMPK activation
  254. Activation of AMPK is necessary for killing cancer cells and sparing cardiac cells
  255. Activation of AMPK improves lipopolysaccharide-induced dysfunction of the blood–brain barrier in mice
  256. PPARβ activation induces rapid changes of both AMPK subunit expression and AMPK activation in mouse skeletal muscle
  257. Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary …
  258. Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27 Kip1 or p21 Cip1
  259. Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells
  260. Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells
  261. Activation of AMPK by the Putative Dietary Restriction Mimetic Metformin Is Insufficient to Extend Lifespan in Drosophila
  262. Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model
  263. Activation of AMPK improves inflammation and insulin resistance in adipose tissue and skeletal muscle from pregnant women
  264. ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis
  265. AMPK suppresses vascular inflammation in vivo by inhibiting signal transducer and activator of transcription-1
  266. Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma
  267. Low concentration of metformin induces a p53-dependent senescence in hepatoma cells via activation of the AMPK pathway
  268. Identification of adenine modulating AMPK activation in NIH/3T3 cells by proteomic approach
  269. Activation of AMPK α-and γ-isoform complexes in the intact ischemic rat heart
  270. Effects of biotin supplementation in the diet on adipose tissue cGMP concentrations, AMPK activation, lipolysis, and serum-free fatty acid levels
  271. Sulforaphane induced adipolysis via hormone sensitive lipase activation, regulated by AMPK signaling pathway
  272. Stilbenoids from Rheum undulatum Protect Hepatocytes Against Oxidative Stress Through AMPK Activation
  273. Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway
  274. Nitric oxide-induced autophagy in MC3T3-E1 cells is associated with cytoprotection via AMPK activation
  275. Phosphorylation of adipose triglyceride lipase Ser404 is not related to 5′-AMPK activation during moderate-intensity exercise in humans
  276. Caudal fourth ventricular administration of the AMPK activator 5‐aminoimidazole‐4‐carboxamide‐riboside regulates glucose and counterregulatory hormone profiles …
  277. Activation of AMPK by pterostilbene suppresses lipogenesis and cell-cycle progression in p53 positive and negative human prostate cancer cells
  278. Reduction of lipid accumulation in white adipose tissues by Cassia tora (Leguminosae) seed extract is associated with AMPK activation
  279. Fenofibrate Improves Renal Lipotoxicity through Activation of AMPK-PGC-1α in db/db Mice
  280. 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation
  281. Aging elevates basal adenosine monophosphate-activated protein kinase (AMPK) activity and eliminates hypoxic activation of AMPK in mouse liver
  282. The proteasome inhibitor bortezomib induces testicular toxicity by upregulation of oxidative stress, AMP-activated protein kinase (AMPK) activation and deregulation of …
  283. Remodeling glucose and lipid metabolism through AMPK activation: relevance for treating obesity and type 2 diabetes
  284. AMPK inhibits MTDH expression via GSK 3β and SIRT 1 activation: potential role in triple negative breast cancer cell proliferation
  285. The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism
  286. AMPK-dependent phosphorylation of GAPDH triggers Sirt1 activation and is necessary for autophagy upon glucose starvation
  287. Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)
  288. The dipeptidyl peptidase-4 inhibitor teneligliptin attenuates hepatic lipogenesis via AMPK activation in non-alcoholic fatty liver disease model mice
  289. Effects of AMPK activators on the sub-cellular distribution of fatty acid transporters CD36 and FABPpm
  290. A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism
  291. Activation of AMPK restricts coxsackievirus B3 replication by inhibiting lipid accumulation
  292. Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre‐activation of AMPK‐dependent autophagy
  293. Hypothalamic AMPK activation blocks lipopolysaccharide inhibition of glucose production in mice liver
  294. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a …
  295. Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade
  296. Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK
  297. A novel AMPK activator reduces glucose uptake and inhibits tumor progression in a mouse xenograft model of colorectal cancer
  298. AMPK activation with AICAR provokes an acute fall in plasma [K+]
  299. Stimulation of glucose transport in response to activation of distinct AMPK signaling pathways
  300. Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway
  301. Omega-3 polyunsaturated fatty acids antagonize macrophage inflammation via activation of AMPK/SIRT1 pathway
  302. AS160 phosphorylation is associated with activation of α2β2γ1- but not α2β2γ3-AMPK trimeric complex in skeletal muscle during exercise in humans
  303. Sasa quelpaertensis Nakai extract and its constituent p-coumaric acid inhibit adipogenesis in 3T3-L1 cells through activation of the AMPK pathway
  304. Age and obesity-associated changes in the expression and activation of components of the AMPK signaling pathway in human right atrial tissue
  305. AICAR induced AMPK activation potentiates neuronal insulin signaling and glucose uptake
  306. Small-molecule activators of AMP-activated protein kinase (AMPK), RSVA314 and RSVA405, inhibit adipogenesis
  307. Activation of the AMPK-FOXO3 pathway reduces fatty acid–induced increase in intracellular reactive oxygen species by upregulating thioredoxin
  308. LPS inhibits caspase 3-dependent apoptosis in RAW264. 7 macrophages induced by the AMPK activator AICAR
  309. AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets
  310. Activation of cannabinoid CB2 receptor–mediated AMPK/CREB pathway reduces cerebral ischemic injury
  311. Glucose deprivation accelerates VLDL receptor-mediated TG-rich lipoprotein uptake by AMPK activation in skeletal muscle cells
  312. AZD8055 induces cell death associated with autophagy and activation of AMPK in hepatocellular carcinoma
  313. AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol
  314. AICAR, an activator of AMPK, inhibits adipogenesis via the WNT/β-catenin pathway in 3T3-L1 adipocytes
  315. AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells
  316. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC
  317. Hypoxia induces expression and activation of AMPK in rat dental pulp cells
  318. Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes
  319. Activation of AMPK participates hydrogen sulfide-induced cyto-protective effect against dexamethasone in osteoblastic MC3T3-E1 cells
  320. l-Glutamine enhances enterocyte growth via activation of the mTOR signaling pathway independently of AMPK
  321. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum
  322. AICAR-induced activation of AMPK inhibits TSH/SREBP-2/HMGCR pathway in liver
  323. NAD blocks high glucose induced mesangial hypertrophy via activation of the sirtuins-AMPK-mTOR pathway
  324. Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism
  325. Activation of insulin signaling and energy sensing network by AICAR, an AMPK activator in insulin resistant rat tissues
  326. IGF-1 receptor signaling pathways and effects of AMPK activation on IGF-1-induced progesterone secretion in hen granulosa cells
  327. Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats
  328. Flufenamic acid promotes angiogenesis through AMPK activation
  329. Resveratrol inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation
  330. Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway
  331. Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK)
  332. Olanzapine induces glucose intolerance through the activation of AMPK in the mouse hypothalamus
  333. Glucose-induced repression of PPARα gene expression in pancreatic β-cells involves PP2A activation and AMPK inactivation
  334. … in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation
  335. Grape seed extract and resveratrol prevent 4‐nitroquinoline 1‐oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological …
  336. AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents
  337. … in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation
  338. Lipid metabolism disturbances and AMPK activation in prolonged propofol-sedated rabbits under mechanical ventilation
  339. AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1
  340. Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via AMPK activation
  341. Cigarette smoke exposure triggers the autophagic cascade via activation of the AMPK pathway in mice
  342. Sestrin2 protects dopaminergic cells against rotenone toxicity through AMPK-dependent autophagy activation
  343. Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective …
  344. Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of m TORC 1 complex components in human cancer cells
  345. Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway
  346. Poliothrysoside and its derivatives as novel insulin sensitizers potentially driving AMPK activation and inhibiting adipogenesis
  347. Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment
  348. (–)-Epigallocathechin-3-gallate, an AMPK activator, decreases ovariectomy-induced bone loss by suppression of bone resorption
  349. Fermented ginseng attenuates hepatic lipid accumulation and hyperglycemia through AMPK activation
  350. FATP1 mediates fatty acid-induced activation of AMPK in 3T3-L1 adipocytes
  351. Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells
  352. Jinlida granule inhibits palmitic acid induced-intracellular lipid accumulation and enhances autophagy in NIT-1 pancreatic β cells through AMPK activation
  353. Saponins from Rubus parvifolius L. induce apoptosis in human chronic myeloid leukemia cells through AMPK activation and STAT3 inhibition
  354. Enhanced expression of WD repeat-containing protein 35 via CaMKK/AMPK activation in bupivacaine-treated Neuro2a cells
  355. Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK …
  356. AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation
  357. Induction of autophagy in hepatocellular carcinoma cells by SB203580 requires activation of AMPK and DAPK but not p38 MAPK
  358. Activation of autophagy and AMPK by gamma‐tocotrienol suppresses the adipogenesis in human adipose derived stem cells
  359. SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis
  360. Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1
  361. CaM kinase kinase β-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells
  362. Prior serum-and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake
  363. A1 adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death
  364. Osteogenesis and angiogenesis induced by porous β-CaSiO3/PDLGA composite scaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways
  365. Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in …
  366. Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK
  367. Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection
  368. … inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells
  369. Activation of autophagy via Ca2+-dependent AMPK/mTOR pathway in rat notochordal cells is a cellular adaptation under hyperosmotic stress
  370. PDGF-induced airway smooth muscle proliferation is associated with Human antigen R activation and could be weakened by AMPK activation
  371. AMP‐activated protein kinase (AMPK)–induced preconditioning in primary cortical neurons involves activation of MCL‐1
  372. Defective myofibroblast formation from mesenchymal stem cells in the aging murine heart: rescue by activation of the AMPK pathway
  373. The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content
  374. eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1
  375. Dietary aloe reduces adipogenesis via the activation of AMPK and suppresses obesity-related inflammation in obese mice
  376. GYY4137, a novel hydrogen sulfide-releasing molecule, likely protects against high glucose-induced cytotoxicity by activation of the AMPK/mTOR signal pathway in …
  377. When metabolism rules perfusion: AMPK-mediated endothelial nitric oxide synthase activation
  378. NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation
  379. Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK
  380. Persimmon tannin accounts for hypolipidemic effects of persimmon through activating of AMPK and suppressing NF-κB activation and inflammatory responses in high …
  381. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation
  382. … glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK
  383. Phyllostachys edulis extract induces apoptosis signaling in osteosarcoma cells, associated with AMPK activation
  384. Activation of autophagic flux against xenoestrogen bisphenol-A-induced hippocampal neurodegeneration via AMP kinase (AMPK)/mammalian target of …
  385. Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes
  386. Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells
  387. Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of …
  388. … of glucose uptake in muscular cell by soybean charged peptides isolated by electrodialysis with ultrafiltration membranes (EDUF): activation of the AMPK pathway
  389. Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation
  390. Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling
  391. Methyl cinnamate inhibits adipocyte differentiation via activation of the CaMKK2–AMPK pathway in 3T3-L1 preadipocytes
  392. Dehydrozingerone exerts beneficial metabolic effects in high‐fat diet‐induced obese mice via AMPK activation in skeletal muscle
  393. Activators of AMPK: Not just for type II diabetes
  394. A pharmacological activator of AMP-activated protein kinase (AMPK) induces astrocyte stellation
  395. Calebin‐A inhibits adipogenesis and hepatic steatosis in high‐fat diet‐induced obesity via activation of AMPK signaling
  396. … overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation
  397. … -activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and …
  398. RETRACTED ARTICLE: Betulin inhibits lung carcinoma proliferation through activation of AMPK signaling
  399. Effect of caloric restriction and AMPK activation on hepatic nuclear receptor, biotransformation enzyme, and transporter expression in lean and obese mice
  400. FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway
  401. Chronic activation of central AMPK attenuates glucose-stimulated insulin secretion and exacerbates hepatic insulin resistance in diabetic rats
  402. CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells
  403. Resveratrol via activation of AMPK lowers blood pressure in DOCA-salt hypertensive mice
  404. Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK
  405. Piperonal prevents high-fat diet-induced hepatic steatosis and insulin resistance in mice via activation of adiponectin/AMPK pathway
  406. Activation of autophagy by globular adiponectin attenuates ethanol-induced apoptosis in HepG2 cells: involvement of AMPK/FoxO3A axis
  407. Nobiletin suppresses adipogenesis by regulating the expression of adipogenic transcription factors and the activation of AMP-activated protein kinase (AMPK)
  408. Improving arteriovenous fistula patency: transdermal delivery of diclofenac reduces cannulation-dependent neointimal hyperplasia via AMPK activation
  409. (+)-Catechin attenuates NF-κB activation through regulation of Akt, MAPK, and AMPK signaling pathways in LPS-induced BV-2 microglial cells
  410. Metabolic respiration induces AMPK-and Ire1p-dependent activation of the p38-Type HOG MAPK pathway
  411. … as a potential anticancer agent against human prostate cancer–a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation
  412. Exendin-4 attenuates cardiac hypertrophy via AMPK/mTOR signaling pathway activation
  413. Stilbene analogs of resveratrol improve insulin resistance through activation of AMPK
  414. Green tomato extract attenuates high-fat-diet-induced obesity through activation of the AMPK pathway in C57BL/6 mice
  415. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
  416. Activation of AMPK in human fetal membranes alleviates infection-induced expression of pro-inflammatory and pro-labour mediators
  417. Effects of aging on cardiac and skeletal muscle AMPK activity: basal activity, allosteric activation, and response to in vivo hypoxemia in mice
  418. AKT and AMPK activation after high-fat and high-glucose in vitro treatment of prostate epithelial cells
  419. Resistance exercise-induced S6K1 kinase activity is not inhibited in human skeletal muscle despite prior activation of AMPK by high-intensity interval cycling
  420. Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP …
  421. … purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activity
  422. Activation of AMPK inhibits cholera toxin stimulated chloride secretion in human and murine intestine
  423. Snf1/AMPK promotes the formation of Kog1/Raptor-bodies to increase the activation threshold of TORC1 in budding yeast
  424. Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM‐5 leukemia cells
  425. CTRP5 ameliorates palmitate-induced apoptosis and insulin resistance through activation of AMPK and fatty acid oxidation
  426. Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a …
  427. … inhibit UVB-Induced MMP expression and promote type I procollagen production via repression of MAPK/AP-1/NF-κB and activation of AMPK/Nrf2 in HaCaT cells and …
  428. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression
  429. … stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle
  430. Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation
  431. Regulation of ERK1/2 by ouabain and Na-K-ATPase-dependent energy utilization and AMPK activation in parotid acinar cells
  432. Effects of Icariin on insulin resistance via the activation of AMPK pathway in C2C12 mouse muscle cells
  433. AICAR-induced activation of AMPK negatively regulates myotube hypertrophy through the HSP72-mediated pathway in C2C12 skeletal muscle cells
  434. Ginsenoside Rh2 (S) induces differentiation and mineralization of MC3T3-E1 cells through activation of the PKD/AMPK signaling pathways
  435. The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading …
  436. 8-Chloroadenosine sensitivity in renal cell carcinoma is associated with AMPK activation and mTOR pathway inhibition
  437. Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation
  438. Adiponectin offers protection against L166P mutant DJ-1-induced neuronal cytotoxicity mediated by APPL1-dependent AMPK activation
  439. Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR‐δ/AMPK pathway
  440. Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence
  441. Metformin enhances radiation response of ECa109 cells through activation of ATM and AMPK
  442. Gomisin J inhibits oleic acid-induced hepatic lipogenesis by activation of the AMPK-dependent pathway and inhibition of the hepatokine fetuin-A in HepG2 cells
  443. Does LKB1 mediate activation of hepatic AMP-protein kinase (AMPK) and sirtuin1 (SIRT1) after Roux-en-Y gastric bypass in obese rats?
  444. Melanocortin-induced PKA activation inhibits AMPK activity via ERK-1/2 and LKB-1 in hypothalamic GT1-7 cells
  445. Compound C inhibits hypoxic activation of HIF-1 independent of AMPK
  446. Adiponectin mediated APPL1‐AMPK signaling induces cell migration, MMP activation, and collagen remodeling in cardiac fibroblasts
  447. Mulberry 1-deoxynojirimycin pleiotropically inhibits glucose-stimulated vascular smooth muscle cell migration by activation of AMPK/RhoB and down-regulation of …
  448. The Polyphenol Extract from Sechium edule Shoots Inhibits Lipogenesis and Stimulates Lipolysis via Activation of AMPK Signals in HepG2 Cells
  449. Constitutive activation of AMPK α1 in vascular endothelium promotes high‐fat diet‐induced fatty liver injury: Role of COX‐2 induction
  450. High glucose promotes gap junctional communication in cultured neonatal cardiac fibroblasts via AMPK activation
  451. Ischemia-induced activation of AMPK does not increase glucose uptake in glycogen-replete isolated working rat hearts
  452. Reduction in neural performance following recovery from anoxic stress is mimicked by AMPK pathway activation
  453. CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet …
  454. Polysaccharide from Fuzi likely protects against starvation-induced cytotoxicity in H9c2 cells by increasing autophagy through activation of the AMPK/mTOR pathway
  455. TLR4 engagement inhibits AMPK activation through a HMGB1 dependent mechanism
  456. … tumor necrosis factor‑α‑induced expression of inflammatory molecules and activation of nuclear factor‑κB via the activation of AMPK in vascular endothelial …
  457. Anti-diabetic effects of Korean red pepper via AMPK and PPAR-γ activation in C2C12 myotubes
  458. Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation
  459. Corpus Cavernosal Smooth Muscle Relaxation Effect of a Novel AMPK Activator, Beta‐Lapachone
  460. Brown Alga Ecklonia cava Polyphenol Extract Ameliorates Hepatic Lipogenesis, Oxidative Stress, and Inflammation by Activation of AMPK and SIRT1 in High-Fat Diet …
  461. Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activation
  462. The effects of novel AMPK activator on human vascular endothelial cells
  463. Reactivation of latently infected HIV-1 viral reservoirs and correction of aberrant alternative splicing in the LMNA gene via AMPK activation: Common mechanism of …
  464. Insulin downregulates SIRT1 and AMPK activation and is associated with changes in liver fat, but not in inflammation and mitochondrial oxidative capacity, in …
  465. Activation of the AMP-activated protein kinase (AMPK) by nitrated lipids in endothelial cells
  466. Lipopolysaccharides reduce adipogenesis in 3T3-L1 adipocytes through activation of NF-κB pathway and downregulation of AMPK expression
  467. Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer
  468. Xanthigen attenuates high-fat diet-induced obesity through down-regulation of PPARγ and activation of the AMPK pathway
  469. AMPK-activated protein kinase activation by Impatiens balsamina L. is related to apoptosis in HSC-2 human oral cancer cells
  470. Exogenous activation of LKB1/AMPK signaling induces G1 arrest in cells with endogenous LKB1 expression
  471. The selected flavonol glycoside derived from Sophorae Flos improves glucose uptake and inhibits adipocyte differentiation via activation AMPK in 3T3-L1 cells
  472. Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways
  473. Ramipril protects the endothelium from high glucose–induced dysfunction through CaMKKβ/AMPK and heme oxygenase-1 activation
  474. Activation of AMPK/TSC 2/PLD by Alcohol Regulates m TORC 1 and m TORC 2 Assembly in C 2 C 12 Myocytes
  475. Chitooligosaccharide induces mitochondrial biogenesis and increases exercise endurance through the activation of Sirt1 and AMPK in rats
  476. Activation of AMPK in rat hypothalamus participates in cold‐induced resistance to nutrient‐dependent anorexigenic signals
  477. Aβ peptide secretion is reduced by Radix Polygalae‑induced autophagy via activation of the AMPK/mTOR pathway
  478. Activation of AMPK–Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects
  479. GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK …
  480. Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells
  481. IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway
  482. Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi
  483. Long-term consumption of Platycodi radix ameliorates obesity and insulin resistance via the activation of AMPK pathways
  484. Absence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK
  485. TMP21 modulates cell growth in papillary thyroid cancer cells by inducing autophagy through activation of the AMPK/mTOR pathway
  486. … attenuates high glucose‐induced hepatic lipogenesis in human H ep G 2 cells through activation of the liver kinase B 1 and silent information regulator T 1/AMPK …
  487. … apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species‐inducible protein kinases (p38‐MAPK, AMPK)
  488. Physiological role for Angptl4/fiaf in exercise-induced muscle AMPK activation
  489. (+)-Catechin Attenuates NF-κB Activation Through Regulation of Akt, MAPK, and AMPK Signaling Pathways in LPS-Induced BV-2 Microglial Cells.
  490. Development of potent adenosine monophosphate activated protein kinase (AMPK) activators
  491. The nuclear protein Artemis promotes AMPK activation by stabilizing the LKB1–AMPK complex
  492. Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling
  493. Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans
  494. Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity
  495. Cooperativity between inhibition of cytosolic K+ efflux and AMPK activation during suppression of hypoxia-induced cellular apoptosis
  496. Activation of AMPK reduces the co-transporter activity of NKCC1
  497. Yhhu981, a novel compound, stimulates fatty acid oxidation via the activation of AMPK and ameliorates lipid metabolism disorder in ob/ob mice
  498. Licochalcone suppresses LXRα-induced hepatic lipogenic gene expression through AMPK/Sirt1 pathway activation
  499. Korean red ginseng attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells
  500. Phosphorylation and activation of AMP-activated protein kinase (AMPK) by metformin in the human ovary requires insulin
  501. Ca2+/Calmodulin-Dependent Kinase Kinase β (CaMKKβ) Contributes to AMPK Activation in the Heart during Hypoxia
  502. Resveratrol down-regulates a glutamate-induced tissue plasminogen activator via Erk and AMPK/mTOR pathways in rat primary cortical neurons
  503. N-Hydroxycinnamide Derivatives of Osthole Ameliorate Hyperglycemia through Activation of AMPK and p38 MAPK
  504. Ion channel regulation by the LKB1-AMPK signalling pathway: the key to carotid body activation by hypoxia and metabolic homeostasis at the whole body level
  505. Zyflamend, a polyherbal mixture, inhibits lipogenesis and mTORC1 signalling via activation of AMPK
  506. Physical exercise decreases fasting hyperglycemia in diabetic mice through AMPK activation
  507. AMPK activators modulate pro-inflammatory responses in human adipocytes
  508. Erratum: A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3.
  509. The activation of AMPK in cardiomyocytes at the very early stage of hypoxia relies on an adenine nucleotide-independent mechanism
  510. Valsartan independent of AT1 receptor inhibits tissue factor, TLR‐2 and ‐4 expression by regulation of Egr‐1 through activation of AMPK in diabetic conditions
  511. Ablation of Lgr4 enhances energy adaptation in skeletal muscle via activation of Ampk/Sirt1/Pgc1α pathway
  512. ERK1/2 antagonize AMPK-dependent regulation of FcεRI-mediated mast cell activation and anaphylaxis
  513. The ubiquitin-associated domain of AMPK-related protein kinases allows LKB1-induced phosphorylation and activation
  514. … of ouabain signaling. Focus on “Regulation of ERK1/2 by ouabain and Na-K-ATPase-dependent energy utilization and AMPK activation in parotid acinar cells …
  515. … triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non …
  516. Compound 13, an α1-selective small molecule activator of AMPK, inhibits Helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis
  517. Myeloid derived suppressor cell mediated AMPK activation regulates multiple myeloma cell survival
  518. Estradiol inhibits cytokine-induced expression of VCAM-1 and ICAM-1 in cultured human endothelial cells via AMPK/PPARα activation
  519. … derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway
  520. Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation
  521. Substance P enhances the activation of AMPK and cellular lipid accumulation in 3T3‑L1 cells in response to high levels of glucose
  522. Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK
  523. The effect of AMPK activation on Alzheimer’s-like symptoms in APP mice
  524. Chronic AMPK activation prevents 20-HETE induced endothelial dysfunction
  525. DPP‐4 Inhibitor Linagliptin Attenuates Aβ‐induced Cytotoxicity through Activation of AMPK in Neuronal Cells
  526. AMPK activation in health and disease
  527. Rutin Reduces Body Weight with an Increase of Muscle Mitochondria Biogenesis and Activation of AMPK in Diet‐induced Obese Rats
  528. The effect of AMPK activation on Wnt and sFRP5 in TNF-α induced adipocyte metabolic dysfunction in 3T3-L1 cell
  529. Tumor suppressor gene ING3 induces cardiomyocyte hypertrophy via inhibition of AMPK and activation of p38 MAPK signaling
  530. Antitumor mechanism of metformin via adenosine monophosphate-activated protein kinase (AMPK) activation
  531. β‐elemene inhibited expression of DNA methyltransferase 1 through activation of ERK 1/2 and AMPK α signalling pathways in human lung cancer cells: the role of …
  532. Gastrodin ameliorates oleic acid-induced fat accumulation through activation of AMPK pathway in HL-7702 cells
  533. The effects of NT1014, a novel AMPK activator, compared to metformin, on ovarian cancer cell proliferation, apoptosis, and tumor growth
  534. Usnic acid inhibits ER stress activation through AMPK signaling pathway in rat cardiomyocytes
  535. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
  536. Estradiol regulates dorsal vagal complex signal transduction pathway transcriptional reactivity to the AMPK activator 5-aminoimidazole-4-carboxamide-riboside …
  537. Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation
  538. AS160 phosphorylation is associated with activation of 2 2 1-but not 2 2 3-AMPK trimeric complex in skeletal muscle during exercise in humans
  539. Antidiabetic effects of Nigella sativa are mediated by activation of insulin and AMPK pathways, and by mitochondrial uncoupling
  540. AMPK over-activation leads to accumulation of α-synuclein oligomers and decrease of neurites
  541. Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells
  542. Impact of AMPKgamma silencing on AMPK activation and intracellular lipids regulation
  543. Hypoxia sensitizes skeletal muscle to fasting-induced muscle atrophy; role of AMPK activation
  544. … enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as …
  545. Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK
  546. Induction of apoptosis by ethanol extract of Cnidium officinale in human leukemia U937 cells through activation of AMPK
  547. Hyperglycemia enhances IGF-I responses and alters the AMPK activation profile that protects against metformin-induced growth inhibition in pancreatic cancer cells
  548. Dietary L‐lysine supplementation reduces de novo lipogenesis via AMPK activation and malonyl‐CoA suppression
  549. New potent AMPK activators against colorectal cancer stem cells
  550. Homogenous fluorescent assays for characterizing small-molecule activators of AMP-activated protein kinase (AMPK)
  551. Ischaemia-reperfusion-induced kidney injury: Experimental studies on the effects of caloric restriction, AMPK activator AICAR and α2-adrenoceptor agonists in the rat
  552. A novel role for AMPK as a molecular switch regulating the activation of Akt and RAS signaling in acute lymphoblastic leukemia
  553. Blood glucose lowering effect of Tridax procumbens in type 2 diabetes may be attributed to AMPK activation and suppression of hepatic gluconeogenesis (259.8)
  554. Feeding long-chain n− 3 polyunsaturated fatty acids during gestation increases intestinal glucose absorption potentially via the acute activation of AMPK
  555. Efavirenz induces alterations in lipid metabolism through AMPK activation
  556. Metformin inhibits TGF-b-induced myofibroblast differentiation through AMPK activation
  557. Adiponectin Repressed Proliferation of Colon Cancer Cells via AMPK Activation
  558. New avenue to AMPK activation
  559. AMP-activated protein kinase (AMPK) activation for the treatment of mitochondrial disease
  560. P179 Celecoxib-mediated activation of an AMPK-CREB-Nrf2 dependent pathway: a novel mechanism for endothelial cytoprotection in chronic systemic inflammation
  561. (S)-[6]-Gingerol enhances glucose uptake in L6 myotubes by activation of AMPK in response to [Ca2+]i
  562. Protection of retinal photoreceptors by activation of AMPK with metformin
  563. Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion-injury 2
  564. AdipoRon, the First Orally Active Adiponectin Receptor Activator, Attenuates Post-ischemic Myocardial Apoptosis via AMPK Activation and Oxidative Stress Reduction
  565. PPARβ/δ Activation prevents hypertriglyceridemia caused by a high fat diet. Involvement of AMPK and PGC-1α-Lipin1-PPARα pathway
  566. Short‐term AMPK activation improves vascular endothelial function in old mice by a different mechanism than habitual aerobic exercise
  567. AMPK activation by AICAR induces mitochondrial biogenesis in the inner ear
  568. Adiponectin deficiency induced cognitive impairment in aging mice through reductions in insulin sensitivity and AMPK activation (S8. 003)
  569. Activation of AMPK and PPARγby emodin influences glucose uptake in 3 T3-L1 adipocytes
  570. Abstract P215: Role for Reduced MIF Secretion in Attenuated AMPK Activation and Ischemic Recovery in the Senescent Heart
  571. Polo-like kinase 1 directs the AMPK-mediated activation of myosin regulatory light chain at the cytokinetic cleavage furrow independently of energy balance
  572. Effects of the combined treatment with AMPK activator and somatostatin-14 on hormone secretion and cell proliferation in cultured GH-secreting pituitary tumor cells
  573. IL15 Promotes Myogenic and Brown Adipose Tissue Associated Genes while Decreasing AMPK Activation in C2C12 Skeletal Muscle Cells
  574. Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
  575. Effects of high hydrostatic pressure extract of Korean fresh ginseng on hepatic lipid accumulation and AMPK activation in HepG2 cells
  576. MicroRNA Let-7f Augments Angiogenic Properties of Endothelial Progenitor Cells through AMPK Activation and MnSOD Induction in Type 1 Diabetes
  577. Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus
  578. Effect of AMPK activation on acute exercise‐induced monocarboxylate transporter (MCT) 1 and MCT4 mRNA expression in skeletal muscle
  579. A Mathematical Model of the Regulation of AMPK Activation
  580. Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells
  581. Recent research progress in small molecule AMPK direct activators
  582. Evidence That Activation of AMPK by DHT Inhibits Granulosa Cell Proliferation by Reducing ERK Phosphorylation.
  583. Metformin improves left ventricular function and survival in heart failure through AMPK-eNOS activation
  584. Activation of AMP-activated protein kinase (AMPK) by the lipid-based Akt inhibitors, phosphatidylinositol ether lipid analogues (PIAs)
  585. Lysophosphatidylcholine‐induced mitochondrial ROS formation and activation of AMPK promote macrophage chemotaxis and efferocytosis
  586. The function of AMPK activation on apoptosis induced by CD437 in cancer cell
  587. The effects of omega-3 polyunsaturated fatty acids on AMPK activation and lipid metabolism in skeletal muscle
  588. An Activator Of AMP Activated Kinase (AMPK) Restores Nrf2 Protein Levels Decreased By Chronic Cigarette Smoke Exposure
  589. Abstract PR15: Antitumor effect of metformin in breast cancer is associated with AMPK and FOXO3a activation
  590. Constitutive activation of AMP-activated protein kinase (AMPK) propel mitochondrial biogenesis
  591. Effects of AMPK Activation on Insulin Sensitivity and Metabolism
  592. AMPK Activation Minimizes Organ Injury by Decreasing Endothelial Activation and Inflammation
  593. Activation of the AMPK regulated metabolic stress response by a small molecule HER2/EGFR tyrosine kinase inhibitor protects cardiac myocytes from apoptotic stimuli
  594. Pre-conditioning’with Latrepirdine, an AMPK activator, delays ALS progression in SOD1G93A mice
  595. The effects of NT1014, a novel AMPK activator, on ovarian cancer cell proliferation and apoptosis.
  596. AMPK activators regulate contractile function of mesenteric arteries
  597. AMPK Activators Cause Different Vasoconstrictor Responses in Small and Large Muscular Arteries
  598. A novel AMPK activator, PT‐1, increases gamma1 AMPKassociated activity, but not gamma3 AMPK‐associated activity or glucose transport
  599. Cellular effects of novel small molecule AMPK activator YLD466D in human prostate cancer
  600. The effects of heat treatment on AMPK activation in skeletal muscle in type 2 diabetic rats
  601. Effects of horse age and feeding status on AMPK activation in horses
  602. Vascular and metabolic actions of insulin and AMPK activation in muscle
  603. A Redox Dependent Mechanism for Regulation of AMPK Activation by Thioredoxin1 During Energy Starvation
  604. Estrogen Receptor‐Alpha Activation of AMPK in Vascular Smooth Muscle Cells and Vascular Tone
  605. Insulin and AMPK activation mimic Fatigue pre-conditioning
  606. UV and H2O2 induce AMPK activation in cultured skin keratinocytes
  607. New Cucurbitane triterpenoids from bitter melon with potent antidiabetic properties associated with activation of AMPK
  608. D-Dopachrome Tautomerase Provides a Novel Cardioprotective Mechanism Through its Modulation on AMPK Activation in Heart During Ischemia-reperfusion
  609. Scalaran-type sesterterpenes from a Marine Sponge Smenospongia species showing the AMPK activation
  610. Metabolic and structural remodeling of heart‐derived H9c2 cells by AMPK activation
  611. BAS/BSCR34 Is an increased AMPK activation during ischaemia essential for the protection of the heart against infarction?
  612. Effect of modulating adenine nucleotide levels on AMPK activation by targeting AMP-metabolizing enzymes
  613. Long term AMPK activation limits obesity induced muscle atrophy
  614. Dynamic transcription factor activities and networks during restores cellular senescence by novel potential AMPK activator from natural compound
  615. Impacts of AMPK activators and metal stressors on energy levels of Neuro 2a cells
  616. M12 A769662 Leads to AMPK Activation, Induces Autophagy and has Beneficial Effects IN HD Cells
  617. Methylene Blue Protects the Liver from Steatohepatitis via AMPK Activation
  618. AMPK activation is indispensible for the protective effects of caloric restriction in afterload-induced heart failure
  619. Metformin mediated AMPK activation inhibits translation initiation in breast cancer cells
  620. Mitochondrial Function and Superoxide Production is Reduced in the Diabetic Kidney and Restored by AMPK Activation
  621. The Effects of Aging on Skeletal Muscle AMPK Activation and an Analysis of Chronic AICAR Treatment on the Aging Phenotype
  622. Regulation of p53 mRNA by AMP Kinase (AMPK) activation in C2C12 myoblasts
  623. AMPK activation and Adenine Nucleotide content in skeletal muscle following different types of high fat feeding
  624. The effect of metformin-induced AMPK activation on adipogenesis and HIV replication
  625. Cardioprotection by temperature preconditioning is mediated by free radicals, PKC and AMPK activation
  626. Sestrin2 Promotes LKB1-Mediated AMPK Activation in the Ischemic Heart
  627. Antioxidant enzyme-mediated survival of ECM-detached breast cancer cells requires AMPK activation
  628. Adenosine Monophosphate Activated Kinase (AMPK) and its Key Role in Catabolism: Structure, Regulation, Biological Activity and Pharmacological Activation.
  629. Abstract A73: AMPK activation mediates dasatinib-induced EGFR degradation and apoptosis in head and neck cancer
  630. AMP‐Kinase (AMPK) activation attenuates LPS‐induced lung microvascular endothelial injury
  631. High glucose-induced oxidative stress alters estrogen effects on ER and ER in human endothelial cells: Reversal by AMPK activator
  632. Sestrin2 Promotes LKB1-Mediated AMPK Activation in the Ischemic Heart
  633. Sestrin2 is cardioprotective against ischemia/reperfusion injury by promoting LKB1‐mediated AMPK activation
  634. Inhibition of mTOR Pathway and Induction of Autophagy Block Lymphoma Cell Growth: Role of AMPK Activation
  635. Supplemental Information Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
  636. Increased myocardial substrate uptake contributes to the protection of ischemic preconditioning: role of insulin-dependent Akt and AMPK activation
  637. Effect of hypoxia on AICAR-induced AMPK activation and cytotoxicity in acute lymphoblastic leukemia cells
  638. 0309: A-769662, a specific AMP-activated protein kinase (AMPK) activator, prevents cardiomyocyte hypertrophy independently of the already identified AMPK …
  639. AMPK leads to p38 MAPK activation and COX-2 gene expression
  640. The combined effects of metformin and exercise on AMPK activation, insulin action, and substrate metabolism in insulin resistant individuals
  641. Injection of AMP‐activated protein kinase (AMPK) activator AICAR acutely reduces blood pressure in Spontaneously Hypertensive Rats
  642. Co-Activation of AMPK and mTORC1 Is Synthetically Lethal in Acute Myeloid Leukemia
  643. Differential AMPK Activation and Contractile Function in Rabbit Leg and Neck Arteries in Response to Oxygen and Glucose Deprivation
  644. The Effects of Chronic AMPK Activation on Hepatic Triglyceride Accumulation and Glycerol-3-Phosphate AcyltransferaseActivity with High Fat Feeding
  645. The Synthetic Polyphenol and AMPK Activator, S17834, Improves Diet-Induced Obesity, Insulin Resistance, Hyperlipidemia, and Atherosclerosis in LDL Receptor …
  646. FXR Activation by Chenodeoxycholic Acid Induces Detoxifying Enzymes through AMPK and ERK1/2-mediated Phosphorylation of C/EBPβ
  647. SIRT3-AMPK Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes PH-HFpEF
  648. Phosphorylation-Dependent Nuclear-Cytoplasmic Translocation of LKB1: A Molecular Mechanism for Adiponectin-and Metformin-Stimulated AMPK Activation.
  649. The MIF Receptor (CD74) Regulates AMPK Activation and Cardiac Injury Following Ischemia
  650. Sevoflurane preconditioning increases AMPK activation during ischaemia and reperfusion in isolated rat hearts: 4AP4-4
  651. Chronic AMPK activation induces beneficial phenotypic adaptations in mdx mouse skeletal muscle
  652. Substance X stimulated Glucose Uptake in HepG2 and Mouse Hepatocyte Cells by AMPK activation.
  653. Lipid emulsion rescue therapy blocks AMPK activation and Akt inhibition induced by bupivcaine cardiotoxicity (1154.9)
  654. Regulation of LKB1-STRAD-MO25 complex expression and activation of AMPK in skeletal muscle by thyroid hormone
  655. Contraction‐induced fatty acid uptake and oxidation are regulated in part via CaMKKβ‐dependent AMPK activation in perfused rat muscle
  656. AMPK Activator AICAR Inhibits Hepatic Gluconeogenesis and Fatty Acid Oxidation.
  657. Activation of AMPK: A necessary element in effective targeted tumor therapy
  658. An Exploratory Analysis of AMPK and ACC Activation in Colorectal Primary Tumors and their Corresponding Metastasis
  659. Targeting Myeloid Derived Suppressor Cells (MDSC) Using a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator: OSU-53.
  660. Effect of pomegranate vinegar on visceral fat reduction via AMPK activation in obese subjects
  661. AMPK activation by a novel small molecule of mitochondrial regulation enhances fatty acid oxidation, ketogenesis and branched chain amino acid catabolism in vivo
  662. The acute insulin sensitizing effects of troglitazone are mediated by AMPK activation and inhibition of pyruvate dehyrogenase activity
  663. AMPK activation vs. inhibition induces apoptosis in acute lymphoblastic leukemia cells by differentially altering PI3K/Akt/mTOR or RAS/cRAF/MEK/Erk signaling
  664. Abstract 708A: Suppression of glycolysis by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib via AMPK activation
  665. HMGCoA Reductase Inhibition Reverses Myocardial Fibrosis and Diastolic Dysfunction Through AMPK Activation in a Mouse Model of Metabolic Syndrome
  666. Abstract LB-171: Dietary agent induced AMPK activation: Targeting stem cells for the prevention of colon cancer
  667. … contribution of utrophin A versus other components of the slow, oxidative phenotype in the beneficial adaptations of dystrophic muscle fibers following AMPK activation
  668. Restoration of Angiogenic Balance and Improved Endothelial Cell Function via Ampk Activation is Hypoxia and Ischemia Dependent in Trophoblast Cells and …
  669. … Novel Mechanism of Preconditioning: Attenuating Reperfusion Injury through Enhanced Myocardial Substrate Uptake via Insulin-Stimulated Akt and AMPK Activation
  670. The Anti‐Lipolytic Effects of Acute AICAR‐Induced AMPK Activation in Visceral and Subcutaneous Rat Adipose Tissue is Independent of HSL Phosphorylation on …
  671. Exogenous AMPK Activation Improves Myofibroblast Maturation and Scar Formation in the Infarcted Aging Heart
  672. Ajoene, a stable garlic byproduct, inhibits high‐fat diet‐induced hepatic steatosis and oxidative injury via LKB1‐mediated AMPK activation
  673. AICAR Induces Apoptosis in Chronic Lymphocytic Leukemia Cells through the Mitochondrial Pathway and Independently of p53 Pathway and AMPK Activation.
  674. Chronic AICAR‐induced AMP‐dependent kinase (AMPK) activation exerts an anti‐lipogenic effect in isolated rat adipocytes
  675. Novel 4-Oxothienopyrimidinyl Propanoic Acid Derivatives as AMPActivated Protein Kinase (AMPK) Activators
  676. Combined grape polyphenols regulate mammalian target of rapamycin (mTOR) signaling via a dual mechanism of Akt inhibition and AMPK activation
  677. Adiponectin Increases DAB2, a Tumor Suppressor Gene, in Human Aortic Smooth Muscle Cells via AMPK Activation
  678. The AMPK activation by sauchinone, a Saururus chinensis lignan, enables hepatocytes to protect against the toxicity induced by iron overload
  679. Docosahexaenoic acid-induced cell death may be related to inhibition of mTOR through AMPK activation and PI3K/Akt inhibition in human non-small cell lung cancer …
  680. Enhanced activation of cellular AMPK by dual small
  681. The effects of NT-1044, a novel AMPK activator, on endometrial cancer cell proliferation and apoptosis
  682. SDF-1ß Protects Cardiac Cells From Nitrosative Damage/ER Stress-mediated Fibrosis Through CXCR7-dependent AMPK Activation and IL-6 Generation
  683. Chronic activation of AMPK limits hepatic triglyceride accumulation independent of changes in total glycerol‐3‐phosphate‐acyltransferase activity
  684. Pemetrexed induces a strong activation of AMPK in human carcinoma cells, even in the absence of LKB1
  685. Effects of Biotin Supplementation in the Diet on Adipose Tissue cGMP Concentrations, AMPK Activation, Lipolysis, and Serum-Free Fatty Acid Levels
  686. P47: AMPK activation by nitrite and metformin increases glut-4 mediated glucose uptake and normalizes pulmonary venous hypertension in a rat model of severe …
  687. AICAR‐induced Activation of AMPK Causes Phosphorylation of p38 MAPK gamma in Resting Skeletal Muscle
  688. Adipose cells induce phospho-Thr-172 AMPK production by epinephrine or CL316243 in mouse 3T3-L1 adipocytes or MAPK activation and G protein …
  689. AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome
  690. 1 AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase 2 activation induced by hyperglycemia in adult cardiomyocytes. 3
  691. Urocortin Stimulates Glucose Uptake in the Hypoxic Heart by Activation of PKCε-AMPK Pathway.
  692. The effects of NT-1044, a novel AMPK activator, on endometrial cancer cell proliferation, apoptosis and cell stress
  693. AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia
  694. Hypoxia Leads to Ca2+/Calmodulin-Dependent Kinase Kinase β (CaMKKβ) Activation/AMPK Phosphorylation, Na,K-ATPase Endocytosis and Impaired Alveolar …
  695. B27 MITOCHONDRIA AND METABOLIC DYSFUNCTION IN PULMONARY HYPERTENSION: Ampk Activation By Nitrite And Metformin Increases Glut4-Mediated …
  696. C96 SUGARS AND FATS-ENERGY UTILIZATION IN PULMONARY HYPERTENSION: Sirt3-Ampk Activation By Nitrite And Metformin Improves Hyperglycemia And …
  697. AICAR Prevents Heat Induced Sudden Death in RyR1 Mutant Mice Independent of AMPK Activation Johanna T. Lanner, Dimitra K. Georgiou, Adan Dagnino …
  698. … to Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression
  699. Folic acid supplementation during high fat diet feeding restores AMP-activated protein kinase (AMPK) activation via an AMP-LKB1 dependent mechanism 2
  700. Evidence for Activation of AMP Kinase (AMPK) in Nephropathic Cystinosis
  701. Regulation of mTOR pathway by the orphan nuclear receptor NR4A1 (TR3/Nur77) in non-small cell lung cancer: Role of TR3 in AMPK activation
  702. Scavenger Receptor CD36 Mediates Inhibition of Cholesterol Synthesis via Activation of the LKB1-AMPK Pathway and Insig1/Insig2 Expression in Hepatocytes
  703. Chronic activation of AMPK enhances insulin‐sensitive fatty acid uptake but not oxidaiton in L6 cells
  704. 022 MitoQ10 decreases AMPK activation in endothelial cells from patients with coronary artery disease and diabetes
  705. AMP Kinase (AMPK) activator 5‐aminoimidazole‐4‐carboxamide‐1‐β‐D‐ribofuranoside (AICAR) alters vascular smooth muscle vasomotor responses in thoracic …
  706. Abstract# 4411: AMP-activated protein kinase (AMPK) activation reduces prostate tumor cell growth via inhibition of fatty acid synthase
  707. Expression and activation of the 5’AMP-activated protein kinase (AMPK) in exercising and energy-depleted cells: an investigation into the molecular basis …
  708. Polysaccharopeptide enhanced the anti-cancer effect of gammatocotrienol through activation of AMPK
  709. Activation of AMP-Activated Protein Kinase (AMPK) by Neuroglucopenia in Hypothalamus Is not Mediated by Ca [sup 2+]/Calmodulin-Dependent Protein Kinase …
  710. Myeloma Cell Proliferation Is Inhibitied by the Activation of Adenosine Monophosphate Activated Protein Kinase (AMPK).
  711. 0358: Differential AMP-activated protein kinase (AMPK) activation in platelets, in response to various agonists. Comparison between human and murine platelets
  712. Anthocyanins of Black Soybean (cv. Cheongja 3) Induce Autophagy via AMPK Activation in U2OS cells
  713. Attenuation of the Leptin-Induced Hypertrophy by NF-kB Inhibition Requires Activation of AMPK in Neonatal Cardiomyocytes
  714. Activation Of AMPK Protects Photoreceptors From Light Damage By Preventing Oxidative Stress, And Requires Signaling Through GP130 And STAT3
  715. Toll-Like Receptor 4-Deficiency Improves Ischemic Cardiomyocytes Contractile Dysfunction via Augmentation of AMPK Activation
  716. Activation of AMPK inhibits pulmonary arterial remodeling
  717. The ATM activator chloroquine stimulates phosphorylation of AMP activated protein kinase (AMPK) and acetyl CoA‐carboxylase (ACC) independent of ATM
  718. Aberrant Activation of γ2-AMPK Increases Cardiac Growth Through Cellular Hypertrophy and Hyperplasia
  719. AMP-activated protein kinase (AMPK) blocks the effects of PDGF by PI3K-independent signals and is downregulated during in vivo activation of hepatic stellate cells
  720. Abstract P198: Aberrant Activation of γ2-AMPK Causes Cardiac Hypertrophy Independent of Glycogen Storage
  721. Activation of AMPK by Pterostilbene Suppresses Lipogenesis and Cell-Cycle Progression in p53 Positive and Negative Human Prostate Cancer Cells
  722. Activation Of AMPK During Angiotensin II Induced Hypertension Improves Endothelial Function By Inhibition Of NADPH Oxidase And Xanthine Oxidase Activity.
  723. Validation of the pitavastatin-induced angiomotin-like protein 1 that controls tight junction stability of lung microvascular endothelial cells via LKB1/AMPK activation
  724. Biotinylated N, N’-diarylureas as probes for the activation of adenosine monophosphate-activated kinase (AMPK)
  725. Gamma‐tocotrienol antagonizes adipogenesis through activation of AMPK/autophagy axis in primary human adipocytes
  726. Resveratrol Displays Cardioprotection in Postinfarction Remodeling Through Autophagic Activation Associated With Ampk but not Sirt1 Pathway
  727. Anti-diabetic effect of Ganoderma lucidum assoiated with the activation of AMPK pathway
  728. Activation of AMP‐activated protein kinase (AMPK) causes vasorelaxation in isolated mesenteric arteries of hypertensive and normotensive rats
  729. Agonist-modulated Activation of AMP-activated Protein Kinase: Evidence for a Novel AMPK-Rac1-Akt-eNOS Pathway in Endothelial Cells
  730. Interleukin-6 Activation of AMPK Involves Both Jak-Stat and Cyclic AMP-Mediated Signaling.
  731. SDF-1β protects cardiac cells from high fat-induced fibrosis through its receptor cxcr7-mediated AMPK/P38 MAPK activation and IL-6 excretion
  732. Translational Research in Acute Lung Injury and Pulmonary Fibrosis: GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and …
  733. … mitigated cardiac hypoxiareoxygenation injury by Suppressed Autophagy and Reduced Cell Death via inhibition of the activation of AMPK-mTOR signalling pathway …
  734. Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPK alpha 2 but not AMPK alpha 1
  735. … -35; Capsaicin suppresses the migration and invasion of cholangiocarcinoma cells by downregulation of matrix metalloproteinase-9 expression via AMPK activation
  736. The Pathogenesis of Noise-Induced Hearing Loss is Mediated by the Activation of AMPK via LKB1 and CaMKKβ
  737. Oxidative Stress Induces GLUT4 Translocation by Dual AMPK Kinase Activation in Cardiac Myocytes
  738. Chronic Activation of AMP‐Activated Protein Kinase (AMPK)‐alpha1 in Liver Leads to Decreased Adiposity in Mice Fed A Normal or High‐Fat Diet
  739. An insulin-independent AMPK-dependent survival pathway is activated in glucose-starved cardiac myocytes through IRS-1/PI3-kinase and rictor-mediated activation …
  740. … Responsiveness In The Metabolic Syndrome After Resistance Training Only May Be Due To Fewer Muscle Slow‐Twitch Fibers And Decreased Activation Of AMPK
  741. Fresh Frozen Plasma Induces Nitric Oxide Production Through AMPK‐Akt‐mediated eNOS Activation
  742. ICAM-1-mediated eNOS activation via calcium and AMPK is required for transendothelial lymphocyte migration
  743. … MATRIX (ECM) REMODELLING INDUCED BY LEPTIN COULD BE ANTAGONISED BY ADIPONECTIN THROUGH THE ACTIVATION OF AMPK VIA ADIPOR1 OF …
  744. Ramipril protects the endothelium from hyperglycaemia‐induced dysfunction through AMPK and HO‐1 activation (851.10)
  745. Central administration of histamine H1 receptor agonist, fMPH, blocks olanzapineinduced activation of ampk-cpt1 signaling in the dorsal vagal complex in rats
  746. Rapid activation by 3, 5, 3′-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways: relation to changes in fuel metabolism and myosin heavy chain …
  747. INCRETIN AMELIORATES DIABETIC MICROANGIOPATHY IN HEART BY ACTIVATION OF AUTOPHAGY VIA PKA/AMPK AXIS.
  748. Late-breaking abstract: Influenza A virus infection reduces alveolar fluid clearance by activation of AMPK and subsequent reduction of Na, K-ATPase protein …
  749. The AMPK-related kinase, Nuak2 is modulated by the activation process and regulates motility of hepatic stellate cells (HSC)
  750. Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells
  751. Research Article The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content
  752. Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2–AMPK Pathway in 3T3-L1 Preadipocytes
  753. Phosphorylation Of The Insulin Receptor By AMPK Promotes Ligand-independent Activation Of The Insulin-signaling Pathway And Promotes Survival Of Glucose …
  754. Carolic Restriction Ameliorates Cardiac Steatosis by Activation of Autophagy via Cyclic AMP/AMPK/PKA Axis
  755. … Dysfunction and Hypertrophy through Impaired PTEN-Induced Activation of PTEN Induced Putative Kinase 1 (Pink1) and AMP-Activated Protein Kinase (AMPK)
  756. Cationic polystyrene nanosphere induces autophagy through inhibition of the Akt/mTOR and activation of the AMPK signaling pathways in macrophage and epithelial …
  757. THE AMPK RELATED KINASE NUAK2 INTERACTS WITH TGF-BETA AND REGULATES THE ACTIVATION PROCESS OF HEPATIC STELLATE CELLS (HSC)
  758. Chronic exposure to palmitate impairs fatty acid oxidation and insulin‐stimulated glucose uptake despite activation of AMPK in skeletal muscle cells
  759. P-215 Induction of apoptosis by 7, 8-dihydroxyflavone in human colon cancer HCT-116 cells through activation of p53 and AMPK signaling pathways
  760. Cucurbitacin E induces apoptosis and attenuates activation of hepatic stellate cells via PI3K/Akt-AMPK-mTOR signaling pathway
  761. Resveratrol-induced activation of the SIRT1/AMPK axis in human CD4 T cells triggers replicative stress and an ATR-dependent cell cycle arrest
  762. GW26-e1362 Activation of Cannabinoid Receptor 2 improves therapeutic efficacy of Adipose-Derived Mesenchymal Stem Cells to alleviate myocardial ischemia injury …
  763. Luminal glucose (G)‐induced activation of intestinal phosphate (Pi) uptakes involves glucose‐6‐phosphate (G6Pase) and AMP‐Kinase (AMPK)
  764. Transient Receptor Potential Vanilloid 1 (TRPV1) activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways.
  765. VCAM-1 promoted by leptin could be offset by adiponectin through the activation of ampk via adipoR1 receptor of VECs in 3D vessel model
  766. … intestinal epithelial cells (IECs) occurs via phosphatidylinositol 3‐kinase (PI3‐K) mediated activation of adenosine monophosphate‐activated protein kinase (AMPK)
  767. Activation of AMP-activated protein kinase (AMPK) inhibits chondrocyte catabolic response to pro-inflammatory cytokines and up-regulates anti-oxidant genes via …
  768. Examination of the domain structure upon binding of allosteric activator 5′-AMP of heterotrimeric AMP-activated protein kinase (AMPK)
  769. Abstract# 3900: Resveratrol suppresses insulin-like growth factor-1 promoted colon cancer cell growth via activation of p53/AMPK/TSC-2 and suppression of IGF-1R …
  770. Activation of TASK‐2 by hypoxia: is it via ROS, AMPK or H2S?
  771. 13: ACTIVATION OF AMPK REDUCES ACUTE RENAL FAILURE AND HEPATIC INJURY IN A RODENT MODEL OF SEPSIS
  772. 940: PHARMACOLOGICAL ACTIVATION OF AMPK IMPROVES CARDIAC DYSFUNCTION IN EXPERIMENTAL SEPSIS IN MICE.
  773. … (ATM) prevents the prolonged increase in phosphorylation of Akt substrate of 160 kDa (AS160) subsequent to activation of the AMP‐activated protein kinase (AMPK)
  774. JKCF1-3 Metformin decreases airway remodeling via activation of AMPK (Inflammatory cells in allergic diseases, Free Paper Session 1, Japan-Korea-China Joint …
  775. VCAM-1 promoted by leptin could be offset by adiponectin through the activation of AMPK via AdipoR1 receptor of VECS in 3D vessel model
  776. Abstract LB-25: Activation of AMPK by ATM in reponse to AICAR and metformin
  777. Loss of AMPK activation promotes the invasion and metastasis of pancreatic cancer through an HSF 1‐dependent pathway
  778. EGCG reduces obesity and white adipose tissue gain partly through AMPK activation in mice
  779. An lncRNA switch for AMPK activation
  780. Lipid accumulation in HepG2 cells is attenuated by strawberry extract through AMPK activation
  781. Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis
  782. AMPK activation by metformin suppresses abnormal extracellular matrix remodeling in adipose tissue and ameliorates insulin resistance in obesity
  783. Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
  784. Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators
  785. Palmitoleic acid improves metabolic functions in fatty liver by PPARα‐dependent AMPK activation
  786. AMPK activation enhances the anti-atherogenic effects of high density lipoproteins in apoE−/− mice
  787. β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation
  788. AMPK activation prevents and reverses drug-induced mitochondrial and hepatocyte injury by promoting mitochondrial fusion and function
  789. AMPK activation promotes tight junction assembly in intestinal epithelial Caco-2 cells
  790. CircACC1 regulates assembly and activation of AMPK complex under metabolic stress
  791. AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue
  792. AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington’s disease
  793. Calcium-oxidant signaling network regulates AMP-activated protein kinase (AMPK) activation upon matrix deprivation
  794. AMPK activation regulates LTBP4-dependent TGF-β1 secretion by pro-inflammatory macrophages and controls fibrosis in Duchenne muscular dystrophy
  795. Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα
  796. Adenosine monophosphate-activated protein kinase (AMPK) activators for the prevention, treatment and potential reversal of pathological pain
  797. Chitosan oligosaccharide suppresses synovial inflammation via AMPK activation: An in vitro and in vivo study
  798. AMPK activation serves a critical role in mitochondria quality control via modulating mitophagy in the heart under chronic hypoxia
  799. Exercise-induced AMPK activation is involved in delay of skeletal muscle senescence
  800. Astragalus Polysaccharide Improves Insulin Sensitivity via AMPK Activation in 3T3-L1 Adipocytes
  801. Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators
  802. Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation
  803. Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes
  804. AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor–Independent Mechanisms Suggests New Uses for This Therapeutic …
  805. Rhizoma coptidis and berberine as a natural drug to combat aging and aging-related diseases via anti-oxidation and AMPK activation
  806. AMPK activators: mechanisms of action and physiological activities
  807. Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism
  808. Metformin prevents nigrostriatal dopamine degeneration independent of AMPK activation in dopamine neurons
  809. Long feeding high-fat diet induces hypothalamic oxidative stress and inflammation, and prolonged hypothalamic AMPK activation in rat animal model
  810. AMPK activation reduces the number of atheromata macrophages in ApoE deficient mice
  811. AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity
  812. Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation
  813. Effects of isorhamnetin on adipocyte mitochondrial biogenesis and AMPK activation
  814. Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation
  815. Sirt6 suppresses high glucose-induced mitochondrial dysfunction and apoptosis in podocytes through AMPK activation
  816. 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming
  817. Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice
  818. … high‐fat‐diet‐induced obesity and anxiety in mice by inducing AMPK activation and SIRT1 expression and inhibiting gut microbiota‐mediated NF‐κB activation
  819. Protective effects of gomisin N against hepatic steatosis through AMPK activation
  820. Inhibition of mi RNA‐27b enhances neurogenesis via AMPK activation in a mouse ischemic stroke model
  821. Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death
  822. Metformin inhibits advanced glycation end products-induced inflammatory response in murine macrophages partly through AMPK activation and RAGE/NFκB …
  823. Linking energy sensing to suppression of JAK-STAT signalling: a potential route for repurposing AMPK activators?
  824. Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-κB pathway
  825. Metformin and glucose starvation decrease the migratory ability of hepatocellular carcinoma cells: targeting AMPK activation to control migration
  826. Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain
  827. Poria cocus wolf extract ameliorates hepatic steatosis through regulation of lipid metabolism, inhibition of ER stress, and activation of autophagy via AMPK activation
  828. Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation
  829. Itraconazole-induced inhibition on human esophageal cancer cell growth requires AMPK activation
  830. Capsaicin targets lipogenesis in HepG2 cells through AMPK activation, AKT inhibition and PPARs regulation
  831. Current evidence for AMPK activation involvement on resveratrol-induced neuroprotection in cerebral ischemia
  832. Genistein-induced LKB1–AMPK activation inhibits senescence of VSMC through autophagy induction
  833. SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
  834. Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB …
  835. AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway
  836. AMPK activation attenuates inflammatory response to reduce ambient PM2. 5-induced metabolic disorders in healthy and diabetic mice
  837. Natural AMPK activators: an alternative approach for the treatment and management of metabolic syndrome
  838. … regulation of the AMPK signaling network in response to exercise and insulin in skeletal muscle of male patients with type 2 diabetes: illumination of AMPK activation …
  839. Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 …
  840. A systems study reveals concurrent activation of AMPK and mTOR by amino acids
  841. Phenformin, but not metformin, delays development of T cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation
  842. AMPK phosphorylation modulates pain by activation of NLRP3 inflammasome
  843. Human sperm motility is downregulated by the AMPK activator A769662
  844. Chicory (Cichorium intybus L.) polysaccharides attenuate high-fat diet induced non-alcoholic fatty liver disease via AMPK activation
  845. Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats
  846. Inhibitory effects of betulinic acid on LPS-induced neuroinflammation involve M2 microglial polarization via CaMKKβ-dependent AMPK activation
  847. AMPK activation by GSK621 inhibits human melanoma cells in vitro and in vivo
  848. Involvement of AMPK activation in the inhibition of hepatic gluconeogenesis by Ficus carica leaf extract in diabetic mice and HepG2 cells
  849. Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts
  850. ALOX12 inhibition sensitizes breast cancer to chemotherapy via AMPK activation and inhibition of lipid synthesis
  851. … osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation
  852. Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation
  853. Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology
  854. Melatonin alleviates oxidative stress-inhibited osteogenesis of human bone marrow-derived mesenchymal stem cells through AMPK activation
  855. AMPK activation by pterostilbene contributes to suppression of hepatic gluconeogenic gene expression and glucose production in H4IIE cells
  856. Adiponectin upregulates MiR-133a in cardiac hypertrophy through AMPK activation and reduced ERK1/2 phosphorylation
  857. Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation
  858. Calcitriol reduces hepatic triglyceride accumulation and glucose output through Ca2+/CaMKKβ/AMPK activation under insulin-resistant conditions in type 2 diabetes …
  859. The suppressive effects of Britannin (Bri) on human liver cancer through inducing apoptosis and autophagy via AMPK activation regulated by ROS
  860. Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism
  861. Inhibition of adipogenesis by diphlorethohydroxycarmalol (DPHC) through AMPK activation in adipocytes
  862. Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver
  863. Policosanol attenuates cholesterol synthesis via AMPK activation in hypercholesterolemic rats
  864. AMPK activation by metformin inhibits local innate immune responses in the isolated rat heart by suppression of TLR 4-related pathway
  865. Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation
  866. Targeting surface nucleolin induces autophagy-dependent cell death in pancreatic cancer via AMPK activation
  867. Vitamin D3 regulates steroidogenesis in granulosa cells through AMP‐activated protein kinase (AMPK) activation in a mouse model of polycystic ovary syndrome
  868. Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice
  869. Indole Derivatives Isolated from Brown Alga Sargassum thunbergii Inhibit Adipogenesis through AMPK Activation in 3T3-L1 Preadipocytes
  870. Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation
  871. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
  872. AMPK activator AICAR promotes 5-FU-induced apoptosis in gastric cancer cells
  873. Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration
  874. Serine prevents LPS-induced intestinal inflammation and barrier damage via p53-dependent glutathione synthesis and AMPK activation
  875. AMPK activation promotes gastroprotection through mutual interaction with the gaseous mediators H2S, NO, and CO
  876. Bavachin from Psoralea corylifolia Improves Insulin-Dependent Glucose Uptake through Insulin Signaling and AMPK Activation in 3T3-L1 Adipocytes
  877. Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation
  878. Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
  879. AMPK activation by AICAR sensitizes prostate cancer cells to radiotherapy
  880. Nootkatone, an AMPK activator derived from grapefruit, inhibits KRAS downstream pathway and sensitizes non-small-cell lung cancer A549 cells to adriamycin
  881. AMPK activation is involved in hypoglycemic and hypolipidemic activities of mogroside-rich extract from Siraitia grosvenorii (Swingle) fruits on high-fat diet …
  882. Mogroside IIIE attenuates LPS‐induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF‐κB axis via AMPK activation
  883. … M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation
  884. Eupatilin ameliorates dextran sulphate sodium-induced colitis in mice partly through promoting AMPK activation
  885. AMPK activation by peri-sciatic nerve administration of ozone attenuates CCI-induced neuropathic pain in rats
  886. Targeting AMPK: from ancient drugs to new small-molecule activators
  887. AMP‐activated protein kinase (AMPK) activator A‐769662 increases intracellular calcium and ATP release from astrocytes in an AMPK‐independent manner
  888. AMPK re-activation suppresses hepatic steatosis but its downregulation does not promote fatty liver development
  889. Kazinol B from Broussonetia kazinoki improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes
  890. Metformin promotes neuronal differentiation and neurite outgrowth through AMPK activation in human bone marrow–mesenchymal stem cells
  891. A novel AMPK activator improves hepatic lipid metabolism and leukocyte trafficking in experimental hepatic steatosis
  892. AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes
  893. Mechanisms of paradoxical activation of AMPK by the kinase inhibitors SU6656 and sorafenib
  894. Chronic activation of γ2 AMPK induces obesity and reduces β cell function
  895. Liver-specific activation of AMPK prevents steatosis on a high-fructose diet
  896. Role of Angptl4/Fiaf in exercise-induced skeletal muscle AMPK activation
  897. An underlying mechanism of dual Wnt inhibition and AMPK activation: mitochondrial uncouplers masquerading as Wnt inhibitors
  898. Cilostazol exerts antiplatelet and anti‐inflammatory effects through AMPK activation and NF‐kB inhibition on hypercholesterolemic rats
  899. Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation
  900. Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function
  901. … of three compounds from ShengMai preparations in mice with myocardial ischemia/reperfusion injury through AMPK activation-mediated mitochondrial fission
  902. Selective activation of AMPK β1-containing isoforms improves kidney function in a rat model of diabetic nephropathy
  903. Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling
  904. Arctigenin inhibits adipogenesis by inducing AMPK activation and reduces weight gain in high‐fat diet‐induced obese mice
  905. Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress
  906. Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells
  907. N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation
  908. Aerobic exercise, but not metformin, prevents reduction of muscular performance by AMPk activation in mice on doxorubicin chemotherapy
  909. Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs
  910. AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle
  911. Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress
  912. Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK
  913. Dapagliflozin Attenuates Na+/H+ Exchanger-1 in Cardiofibroblasts via AMPK Activation
  914. IGF-I and IGFBP-2 stimulate AMPK activation and autophagy, which are required for osteoblast differentiation
  915. Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK
  916. AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of …
  917. High expression of PDLIM5 facilitates cell tumorigenesis and migration by maintaining AMPK activation in prostate cancer
  918. PAN-AMPK activation improves renal function in a rat model of progressive diabetic nephropathy
  919. Immunomodulatory effect of oleoylethanolamide in dendritic cells via TRPV1/AMPK activation
  920. High-intensity high-volume swimming induces more robust signaling through PGC-1α and AMPK activation than sprint interval swimming in m. triceps brachii
  921. AMPK activation of PGC-1α/NRF-1-dependent SELENOT gene transcription promotes PACAP-induced neuroendocrine cell differentiation through tolerance to …
  922. Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK
  923. Genistein ameliorates fat accumulation through AMPK activation in fatty acid‐induced BRL Cells
  924. Targeting myeloid-derived suppressor cells using a novel adenosine monophosphate-activated protein kinase (AMPK) activator
  925. AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells
  926. Resveratrol and metformin recover prefrontal cortex AMPK activation in diet-induced obese mice but reduce BDNF and synaptophysin protein content
  927. Postexercise improvement in glucose uptake occurs concomitant with greater γ3-AMPK activation and AS160 phosphorylation in rat skeletal muscle
  928. AMPK activation ameliorates D-GalN/LPS-induced acute liver failure by upregulating Foxo3A to induce autophagy
  929. Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice
  930. Suppression of hyperglycemia and hepatic steatosis by black-soybean-leaf extract via enhanced adiponectin-receptor signaling and AMPK activation
  931. Metformin improves mitochondrial respiratory activity through activation of AMPK
  932. Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation
  933. AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice
  934. … herbal medicine-derived sulforaphene promotes mitophagic cell death in lymphoma cells through CRM1-mediated p62/SQSTM1 accumulation and AMPK activation
  935. Phenolic acid and flavonoid-rich fraction of Sasa quelpaertensis Nakai leaves prevent alcohol induced fatty liver through AMPK activation
  936. … inhibits H2O2-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activation
  937. γ-Tocotrienol suppression of the Warburg effect is mediated by AMPK activation in human breast cancer cells
  938. Carnosic acid as a component of rosemary extract stimulates skeletal muscle cell glucose uptake via AMPK activation
  939. Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro
  940. Sustained AMPK activation improves muscle function in a mitochondrial myopathy mouse model by promoting muscle fiber regeneration
  941. Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and its potential mechanisms
  942. Barbaloin pretreatment attenuates myocardial ischemia-reperfusion injury via activation of AMPK
  943. GADD45α alleviates acetaminophen-induced hepatotoxicity by promoting AMPK activation
  944. Therapeutic effect of dichloroacetate against atherosclerosis via hepatic FGF21 induction mediated by acute AMPK activation
  945. Metformin-induced AMPK activation stimulates remyelination through induction of neurotrophic factors, downregulation of NogoA and recruitment of Olig2+ precursor …
  946. Activation of skeletal muscle AMPK promotes glucose disposal and glucose lowering in non-human primates and mice
  947. Theaflavin 3, 3′‐digallate reverses the downregulation of connexin 43 and autophagy induced by high glucose via AMPK activation in cardiomyocytes
  948. Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy
  949. Antihyperalgesia effect of AMP-activated protein kinase (AMPK) activators in a mouse model of postoperative pain
  950. AMPK activation by prolonged stimulation with interleukin‐1β contributes to the promotion of GLUT4 translocation in skeletal muscle cells
  951. AMPK activators contribute to maintain naïve pluripotency in mouse embryonic stem cells
  952. Effects of AMPK activation on lipolysis in primary rat adipocytes: studies at different glucose concentrations
  953. YiQiFuMai powder injection attenuates ischemia/reperfusion-induced myocardial apoptosis through AMPK activation
  954. The AMPK activator A769662 blocks voltage-gated sodium channels: discovery of a novel pharmacophore with potential utility for analgesic development
  955. Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy
  956. Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation
  957. AICAR-induced AMPK activation inhibits the noncanonical NF-B pathway to attenuate liver injury and fibrosis in BDL rats
  958. AMPK causes cell cycle arrest in LKB1-deficient cells via activation of CAMKK2
  959. Kahweol inhibits lipid accumulation and induces Glucose-uptake through activation of AMP-activated protein kinase (AMPK)
  960. Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK 4/6‐independent manner
  961. Quercetin oppositely regulates insulin‐mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation
  962. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular …
  963. AMP-activated kinase (AMPK) activation by AICAR in human white adipocytes derived from pericardial white adipose tissue stem cells induces a partial beige …
  964. A‑769662, a direct AMPK activator, attenuates lipopolysaccharide‑induced acute heart and lung inflammation in rats
  965. Noise-induced loss of hair cells and cochlear synaptopathy are mediated by the activation of AMPK
  966. Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy
  967. Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes
  968. Erythrocyte adenosine A2B receptor-mediated AMPK activation: a missing component counteracting CKD by promoting oxygen delivery
  969. Targeted activation of AMPK by GSK621 ameliorates H2O2-induced damages in osteoblasts
  970. Lutein upregulates the PGC‐1α, NRF1, and TFAM expression by AMPK activation and downregulates ROS to maintain mtDNA integrity and mitochondrial biogenesis …
  971. Activation of AMPK attenuated cardiac fibrosis by inhibiting CDK2 via p21/p27 and miR-29 family pathways in rats
  972. Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal
  973. The AMPK-activator AICAR in thyroid cancer: effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration
  974. Anti-hypertrophy effect of atorvastatin on myocardium depends on AMPK activation-induced miR-143-3p suppression via Foxo1
  975. Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4
  976. Anthraquinones from Morinda longissima and their insulin mimetic activities via AMP-activated protein kinase (AMPK) activation
  977. γ-6-Phosphogluconolactone, a byproduct of the oxidative pentose phosphate pathway, contributes to AMPK activation through inhibition of PP2A
  978. AMPK activation by ozone therapy inhibits tissue factor-triggered intestinal ischemia and ameliorates chemotherapeutic enteritis
  979. 4-Nonylphenol induces autophagy and attenuates mTOR-p70S6K/4EBP1 signaling by modulating AMPK activation in Sertoli cells
  980. The AMPK activator AICAR ameliorates age-dependent myocardial injury in murine hemorrhagic shock
  981. HFS‐Triggered AMPK Activation Phosphorylates GSK3β and Induces E‐LTP in Rat Hippocampus In Vivo
  982. Ginger extract ameliorates obesity and inflammation via regulating microRNA-21/132 expression and AMPK activation in white adipose tissue
  983. Gain of function AMP‐activated protein kinase γ3 mutation (AMPKγ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation
  984. Inhibition of autophagy by captopril attenuates prion peptide-mediated neuronal apoptosis via AMPK activation
  985. Piperine ameliorated lupus nephritis by targeting AMPK-mediated activation of NLRP3 inflammasome
  986. Induction of AMPK activation by N,N’-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast …
  987. Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS
  988. Activation of liver AMPK with PF-06409577 corrects NAFLD and lowers cholesterol in rodent and primate preclinical models
  989. Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation
  990. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging …
  991. A new AMPK activator, GSK773, corrects fatty acid oxidation and differentiation defect in CPT2-deficient myotubes
  992. AMPK activation by Tanshinone IIA protects neuronal cells from oxygen-glucose deprivation
  993. Discovery of a novel chalcone derivative inhibiting CFTR chloride channel via AMPK activation and its anti-diarrheal application
  994. Activation of AMPK by metformin promotes renal cancer cell proliferation under glucose deprivation through its interaction with PKM2
  995. Synthesis and In Vitro AMPK Activation of Cycloalkyl/Alkarylbiguanides with Robust In Vivo Antihyperglycemic Action
  996. Enhancement of glucose utilization by loesenerine through AMPK activation in myotubes
  997. Activation of AMPK inhibits PDGF-induced pulmonary arterial smooth muscle cells proliferation and its potential mechanisms
  998. Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study
  999. Caffeic acid expands anti-tumor effect of metformin in human metastatic cervical carcinoma HTB-34 cells: implications of AMPK activation and impairment of fatty acids …
  1000. Propofol inhibits HeLa cells by impairing autophagic flux via AMP-activated protein kinase (AMPK) activation and endoplasmic reticulum stress regulated by …
  1001. Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro
  1002. Ezetimibe, a NPC1L1 inhibitor, attenuates neuronal apoptosis through AMPK dependent autophagy activation after MCAO in rats
  1003. Mevastatin promotes neuronal survival against Aβ-induced neurotoxicity through AMPK activation
  1004. Effect of curcumin (Curcuma longa extract) on LPS-induced acute lung injury is mediated by the activation of AMPK
  1005. AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia
  1006. Electroacupuncture attenuates hepatic lipid accumulation via AMP-activated protein kinase (AMPK) activation in obese rats
  1007. SIRT6 regulates metabolic homeostasis in skeletal muscle through activation of AMPK
  1008. Pharmacological and physiological activation of AMPK improves the spliceopathy in DM1 mouse muscles
  1009. AMPK activation restores ischemic post‑conditioning cardioprotection in STZ‑induced type 1 diabetic rats: Role of autophagy
  1010. AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis
  1011. Nucleosides block AICAR-stimulated activation of AMPK in skeletal muscle and cancer cells
  1012. Pterostilbene inhibits nutrient metabolism and induces apoptosis through AMPK activation in multiple myeloma cells
  1013. A novel AMPK activator hernandezine inhibits LPS-induced TNFα production
  1014. The anti-inflammatory function of adenine occurs through AMPK activation and its downstream transcriptional regulation in THP-1 cells
  1015. Preconditioning mice with activators of AMPK ameliorates ischemic acute kidney injury in vivo
  1016. Molybdenum induces pancreatic β-cell dysfunction and apoptosis via interdependent of JNK and AMPK activation-regulated mitochondria-dependent and ER stress …
  1017. Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF‐1α‐induced pro‐angiogenic factor
  1018. Study on the effect of CaMKKβ‐mediated AMPK activation on the glycolysis and the quality of different altitude postmortem bovines longissimus muscle
  1019. PIK3CA mutation sensitizes breast cancer cells to synergistic therapy of PI3K inhibition and AMPK activation
  1020. Metformin protects cells from mutant huntingtin toxicity through activation of AMPK and modulation of mitochondrial dynamics
  1021. Lateral but not medial hypothalamic AMPK activation occurs at the hypoglycemic nadir in insulin-injected male rats: Impact of caudal dorsomedial hindbrain …
  1022. Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle myotubes
  1023. Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress
  1024. Prior treatment with the AMPK activator AICAR induces subsequently enhanced glucose uptake in isolated skeletal muscles from 24-month-old rats
  1025. Flavonoid derivative exerts an antidiabetic effect via AMPK activation in diet-induced obesity mice
  1026. Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts
  1027. ROS-mediated activation of AMPK plays a critical role in sulforaphane-induced apoptosis and mitotic arrest in AGS human gastric cancer cells.
  1028. Anti-neuroinflammatory effect of emodin in LPS-stimulated microglia: involvement of AMPK/Nrf2 activation
  1029. Determining AMPK activation via the lysosomal v-ATPase-Ragulator-AXIN/LKB1 axis
  1030. Activation of AMPK α2 inhibits airway smooth muscle cells proliferation
  1031. Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling
  1032. Evolution of the synthesis of AMPK activators for the treatment of diabetic nephropathy: From three preclinical candidates to the investigational new drug PF-06409577
  1033. Casein glycomacropeptide‐derived peptide IPPKKNQDKTE ameliorates high glucose‐induced insulin resistance in HepG2 cells via activation of AMPK signaling
  1034. Inhibition of Adipocyte Differentiation by Anthocyanins Isolated from the Fruit of Vitis coignetiae Pulliat is Associated with the Activation of AMPK Signaling Pathway
  1035. ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis
  1036. New insights in the AMPK regulation in chicken spermatozoa: Role of direct AMPK activator and relationship between AMPK and PKA pathways
  1037. Salvinorin A moderates postischemic brain injury by preserving endothelial mitochondrial function via AMPK/Mfn2 activation
  1038. … and activation of α1-and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
  1039. … (YW2065): A therapeutic candidate for colorectal cancer via dual activities of Wnt/β-Catenin signaling inhibition and AMP-Activated protein kinase (AMPK) activation
  1040. 5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes
  1041. The pentacyclic triterpenoid, plectranthoic acid, a novel activator of AMPK induces apoptotic death in prostate cancer cells
  1042. Specific Sirt1 activator-mediated improvement in glucose homeostasis requires Sirt1-independent activation of AMPK
  1043. Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cells
  1044. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK
  1045. … -like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation
  1046. Activation of AMPK prevents monocrotaline-induced extracellular matrix remodeling of pulmonary artery
  1047. Repurposing existing drugs for new AMPK activators as a strategy to extend lifespan: a computer-aided drug discovery study
  1048. Quercetin-induced AMP-activated protein kinase activation attenuates vasoconstriction through LKB1-AMPK signaling pathway
  1049. AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression
  1050. Activation of γ2-AMPK suppresses ribosome biogenesis and protects against myocardial ischemia/reperfusion injury
  1051. AMPK hyper-activation alters fatty acids metabolism and impairs invasiveness of trophoblasts in preeclampsia
  1052. Activation of AMPK attenuates LPS-induced acute lung injury by upregulation of PGC1α and SOD1
  1053. Inhibition by fluoxetine of LH-stimulated cyclic AMP synthesis in tumor Leydig cells partly involves AMPK activation
  1054. Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice
  1055. AMPK activation of apoptotic markers in human breast cancer cell lines with different p53 backgrounds: MCF-7, MDA-MB-231 and T47D cells
  1056. Acanthoic acid protectsagainst ethanol-induced liver injury: Possible role of AMPK activation and IRAK4 inhibition
  1057. Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation
  1058. Metformin inhibits inflammatory signals in the gut by controlling AMPK and p38 MAP kinase activation
  1059. Metformin-induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16
  1060. Comparative transcriptomic analysis of mice liver treated with different AMPK activators in a mice model of atherosclerosis
  1061. Ampk regulates IgD expression but not energy stress with B cell activation
  1062. Cryptotanshinone from the Salvia miltiorrhiza Bunge Attenuates Ethanol-Induced Liver Injury by Activation of AMPK/SIRT1 and Nrf2 Signaling Pathways
  1063. Combination of deep sea water and Sesamum indicum leaf extract prevents high-fat diet-induced obesity through AMPK activation in visceral adipose tissue
  1064. … -dependent protein kinase (AMPK) activator A-769662 causes arterial relaxation by reducing cytosolic free calcium independently of an increase in AMPK …
  1065. κ-opioid receptor activation protects against myocardial ischemia-reperfusion injury via AMPK/Akt/eNOS signaling activation
  1066. A dual AMPK/Nrf2 activator reduces brain inflammation after stroke by enhancing microglia M2 polarization
  1067. Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding
  1068. Activation of AMPK-regulated CRH neurons in the PVH is sufficient and necessary to induce dietary preference for carbohydrate over fat
  1069. Advances on the anti-inflammatory and protective effect of AMPK activators
  1070. Resveratrol via activation of LKB1-AMPK signaling suppresses oxidative stress to prevent endothelial dysfunction in diabetic mice
  1071. … diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK …
  1072. … )phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of …
  1073. AMPK activation, eEF2 inactivation, and reduced protein synthesis in the cerebral cortex of hibernating chipmunks
  1074. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
  1075. … mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway
  1076. Quercetin induces bladder cancer cells apoptosis by activation of AMPK signaling pathway
  1077. Piper retrofractum Vahl. Extract, as a PPARδ and AMPK Activator, Suppresses UVB-Induced Photoaging through Mitochondrial Biogenesis and MMPs …
  1078. Melatonin modulates lipid metabolism in HepG2 cells cultured in high concentrations of oleic acid: AMPK pathway activation may play an important role
  1079. Metformin mediates protection against Legionella pneumonia through activation of AMPK and mitochondrial reactive oxygen species
  1080. BabaoDan attenuates high-fat diet-induced non-alcoholic fatty liver disease via activation of AMPK signaling
  1081. AMP-activated protein kinase (AMPK) activator drugs reduce mechanical allodynia in a mouse model of low back pain
  1082. White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function
  1083. microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation
  1084. Effects of genetic deletion of soluble 5′-nucleotidases NT5C1A and NT5C2 on AMPK activation and nucleotide levels in contracting mouse skeletal muscles
  1085. Activation of AMPK by medicinal plants and natural products: its role in type 2 diabetes mellitus
  1086. L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice
  1087. Hypoglycemic Effect of Opuntia ficus-indica var. saboten Is Due to Enhanced Peripheral Glucose Uptake through Activation of AMPK/p38 MAPK Pathway
  1088. … -mediated regulation of microglial polarization in lipopolysaccharide-induced neuroinflammation via activation of the CaMKKβ/AMPK-PGC-1α signaling axis
  1089. Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
  1090. Hepatic insulin sensitivity is improved in high‐fat diet‐fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis
  1091. … acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation
  1092. Activation of AMPK/SIRT1 axis is required for adiponectin-mediated preconditioning on myocardial ischemia-reperfusion (I/R) injury in rats
  1093. AMPK β1 activation suppresses antipsychotic‐induced hyperglycemia in mice
  1094. Baicalein induces caspase‐dependent apoptosis associated with the generation of ROS and the activation of AMPK in human lung carcinoma A549 cells
  1095. Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway
  1096. Direct activation of adenosine monophosphate-activated protein kinase (AMPK) by PF-06409577 inhibits flavivirus infection through modification of host cell lipid …
  1097. Donepezil improves neuropathy through activation of AMPK signalling pathway in streptozotocin-induced diabetic mice
  1098. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades
  1099. AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR
  1100. Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway
  1101. Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation
  1102. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK
  1103. Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation
  1104. Resveratrol attenuates lipopolysaccharide-induced dysfunction of blood-brain barrier in endothelial cells via AMPK activation.
  1105. Stimulating S-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK
  1106. Combined pharmacological activation of AMPK and PPARδ potentiates the effects of exercise in trained mice
  1107. GYY4137 promotes mice feeding behavior via arcuate nucleus sulfur-sulfhydrylation and AMPK activation
  1108. Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK
  1109. AMPK activation regulates P-body dynamics in mouse sensory neurons in vitro and in vivo
  1110. Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation
  1111. Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK
  1112. CTAB enhances chemo-sensitivity through activation of AMPK signaling cascades in breast cancer
  1113. Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF-κB, uPA activator and MMP9
  1114. Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγ
  1115. AMPK activation mediated by hinokitiol inhibits adipogenic differentiation of mesenchymal stem cells through autophagy flux
  1116. Ginsenoside Rb2 alleviates hepatic lipid accumulation by restoring autophagy via induction of Sirt1 and activation of AMPK
  1117. Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-κB activation
  1118. Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling
  1119. Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway
  1120. Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice
  1121. Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signaling
  1122. … receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway
  1123. Methotrexate improves perivascular adipose tissue/endothelial dysfunction via activation of AMPK/eNOS pathway
  1124. Activation of AMPK is neuroprotective in the oxidative stress by advanced glycosylation end products in human neural stem cells
  1125. Rosmarinic acid mediates mitochondrial biogenesis in insulin resistant skeletal muscle through activation of AMPK
  1126. Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and …
  1127. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling
  1128. Activation of AMPK promotes thyroid cancer cell migration through its interaction with PKM2 and β-catenin
  1129. α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation
  1130. Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer
  1131. Methods to study lysosomal AMPK activation
  1132. Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation
  1133. Activation of AMPK/Nrf2 signalling by Manuka honey protects human dermal fibroblasts against oxidative damage by improving antioxidant response and …
  1134. HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in …
  1135. Omega-3 Polyunsaturated Fatty Acids Prevent Toxoplasma gondii Infection by Inducing Autophagy via AMPK Activation
  1136. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK
  1137. Punicalagin pretreatment attenuates myocardial ischemia-reperfusion injury via activation of AMPK
  1138. Ursolic acid induces mitochondrial biogenesis through the activation of AMPK and PGC-1 in C2C12 myotubes: a possible mechanism underlying its beneficial effect …
  1139. AICAR antiproliferative properties involve the AMPK-independent activation of the tumor suppressors LATS 1 and 2
  1140. Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction
  1141. Inhibition of lipolysis by ilexgenin A via AMPK activation contributes to the prevention of hepatic insulin resistance
  1142. Long non-coding RNA MALAT1 protects human osteoblasts from dexamethasone-induced injury via activation of PPM1E-AMPK signaling
  1143. 13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264. 7 cells and protects endotoxemic mice from organ damage
  1144. … acid attenuates lipopolysaccharide (LPS)-induced acute lung injury via downregulating inflammatory molecules and upregulating HO-1/AMPK activation
  1145. Alleviation of sepsis‑induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p‑S6K and activation of the p‑AMPK pathway
  1146. Activation of the AMPK/Sirt1 pathway by a leucine–metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism …
  1147. Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in …
  1148. Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of …
  1149. M3 muscarinic receptor activation reduces hepatocyte lipid accumulation via CaMKKβ/AMPK pathway
  1150. Irisin alleviates pulmonary epithelial barrier dysfunction in sepsis-induced acute lung injury via activation of AMPK/SIRT1 pathways
  1151. Improvement of lipid and glucose metabolism by capsiate in palmitic acid-treated HepG2 cells via activation of the AMPK/SIRT1 signaling pathway
  1152. Activation of Nrf2 by sulforaphane inhibits high glucose-induced progression of pancreatic cancer via AMPK dependent signaling
  1153. Fibroblast growth factor 19 protects the heart from oxidative stress-induced diabetic cardiomyopathy via activation of AMPK/Nrf2/HO-1 pathway
  1154. Resveratrol activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced inflammation and oxidative stress
  1155. Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
  1156. Pterostilbene decreases cardiac oxidative stress and inflammation via activation of AMPK/Nrf2/HO-1 pathway in fructose-fed diabetic rats
  1157. Berberine protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of AMPK
  1158. YAP inhibition by resveratrol via activation of AMPK enhances the sensitivity of pancreatic cancer cells to gemcitabine
  1159. AMPK negatively regulates peripheral myelination via activation of c-Jun
  1160. Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels
  1161. … of alcoholic liver steatosis by dihydroquercetin through the modulation of AMPK-dependent lipogenesis mediated by P2X7R–NLRP3-inflammasome activation
  1162. Artemisinin Attenuated Hydrogen Peroxide (H2O2)-Induced Oxidative Injury in SH-SY5Y and Hippocampal Neurons via the Activation of AMPK Pathway
  1163. Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway
  1164. Activation of AMPK in human placental explants impairs mitochondrial function and cellular metabolism
  1165. … stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway
  1166. Exacerbated cardiac fibrosis induced by β‐adrenergic activation in old mice due to decreased AMPK activity
  1167. Coumarins ameliorate diabetogenic action of dexamethasone via Akt activation and AMPK signaling in skeletal muscle
  1168. Ethanol extracts of Aster yomena (Kitam.) Honda inhibit adipogenesis through the activation of the AMPK signaling pathway in 3T3-L1 preadipocytes
  1169. Determination of a novel anticancer AMPK activator hernandezine in rat plasma and tissues with a validated UHPLC–MS/MS method: Application to pharmacokinetics …
  1170. Piperine Promotes Glucose Uptake through ROS‐Dependent Activation of the CAMKK/AMPK Signaling Pathway in Skeletal Muscle
  1171. Novel protective mechanism of reducing renal cell damage in diabetes: activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA …
  1172. Adiponectin limits monocytic microparticle-induced endothelial activation by modulation of the AMPK, Akt and NFκB signaling pathways
  1173. Entada phaseoloides extract suppresses hepatic gluconeogenesis via activation of the AMPK signaling pathway
  1174. AMPK activation induced in pemetrexed‐treated cells is associated with development of drug resistance independently of target enzyme expression
  1175. Activation of autophagy through calcium‐dependent AMPK/mTOR and PKC θ pathway causes activation of rat hepatic stellate cells under hypoxic stress
  1176. Madagascine induces vasodilatation via activation of AMPK
  1177. Dopamine receptor D2 activation suppresses the radiosensitizing effect of aripiprazole via activation of AMPK
  1178. Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells
  1179. Facilitation of hippocampal long-term potentiation and reactivation of latent HIV-1 via AMPK activation: common mechanism of action linking learning, memory, and …
  1180. 1, 25-Dihydroxyvitamin D decreases tertiary butyl-hydrogen peroxide-induced oxidative stress and increases AMPK/SIRT1 activation in C2C12 muscle cells
  1181. … migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and AMPK …
  1182. The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway
  1183. Berberine ameliorates high-fat diet-induced non-alcoholic fatty liver disease in rats via activation of SIRT3/AMPK/ACC pathway
  1184. Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway
  1185. Baicalin and its metabolites suppresses gluconeogenesis through activation of AMPK or AKT in insulin resistant HepG-2 cells
  1186. Activation of Nrf2 by phloretin attenuates palmitic acid-induced endothelial cell oxidative stress via AMPK-dependent signaling
  1187. Irisin alleviates pressure overload-induced cardiac hypertrophy by inducing protective autophagy via mTOR-independent activation of the AMPK-ULK1 pathway
  1188. Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK-and PTP1B-dependent processes
  1189. Promotion of Mitochondrial Biogenesis via Activation of AMPK‐PGC1ɑ Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active …
  1190. All-Trans-Retinoic Acid Suppresses Neointimal Hyperplasia and Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via Activation of AMPK …
  1191. Myocardial ischemic postconditioning promotes autophagy against ischemia reperfusion injury via the activation of the nNOS/AMPK/mTOR pathway
  1192. Dexmedetomidine pretreatment inhibits cerebral ischemia/reperfusion‑induced neuroinflammation via activation of AMPK
  1193. Berberine improves motor function recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis via AMPK activation in rats with spinal cord …
  1194. Loss of TP53I11 Enhances the Extracellular Matrix‐independent Survival by Promoting Activation of AMPK
  1195. AMPK-mediated activation of Akt protects renal tubular cells from stress-induced apoptosis in vitro and ameliorates ischemic AKI in vivo
  1196. Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells
  1197. The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathway
  1198. Berberine-induced activation of AMPK increases hepatic FGF21 expression via NUR77
  1199. PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver
  1200. Activation of AMPK/mTORC1-mediated autophagy by metformin reverses Clk1 deficiency-sensitized dopaminergic neuronal death
  1201. Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in …
  1202. Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling
  1203. Polyphenol-enriched extract of Rosa rugosa Thunb regulates lipid metabolism in diabetic rats by activation of AMPK pathway
  1204. Bacterial outer membrane vesicles trigger pre-activation of a xenophagic response via AMPK
  1205. AMPK-mediated cardioprotection of atorvastatin relates to the reduction of apoptosis and activation of autophagy in infarcted rat hearts
  1206. Hypoglycemic effects of esculeoside A are mediated via activation of AMPK and upregulation of IRS-1
  1207. Rosmarinic acid alleviates the endothelial dysfunction induced by hydrogen peroxide in rat aortic rings via activation of AMPK
  1208. 6′-O-acetyl mangiferin from Iris rossii Baker inhibits lipid accumulation partly via AMPK activation in adipogenesis
  1209. Activation of AMPK-dependent SIRT-1 by astragalus polysaccharide protects against ochratoxin A-induced immune stress in vitro and in vivo
  1210. CHIP−/−-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications
  1211. Transposable elements, placental development, and oocyte activation: Cellular stress and AMPK links jumping genes with the creation of human life
  1212. Vitexin alleviates ox-LDL-mediated endothelial injury by inducing autophagy via AMPK signaling activation.
  1213. Protective effects of wedelolactone on dextran sodium sulfate induced murine colitis partly through inhibiting the NLRP3 inflammasome activation via AMPK signaling
  1214. Sestrin2 regulates monocyte activation through AMPK‐mTOR nexus under high‐glucose and dyslipidemic conditions
  1215. Raspberry alleviates obesity-induced inflammation and insulin resistance in skeletal muscle through activation of AMP-activated protein kinase (AMPK) α1
  1216. Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation
  1217. Co-activation of AMPK and mTORC1 as a new therapeutic option for acute myeloid leukemia
  1218. WSF-P-1, a novel AMPK activator, promotes adiponectin multimerization in 3T3-L1 adipocytes
  1219. Globular adiponectin inhibits lipopolysaccharide-primed inflammasomes activation in macrophages via autophagy induction: the critical role of AMPK signaling
  1220. Isogambogenic acid inhibits the growth of glioma through activation of the AMPK-mTOR pathway
  1221. Spatholobus suberectus Exhibits Antidiabetic Activity In Vitro and In Vivo through Activation of AKT-AMPK Pathway
  1222. Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats
  1223. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition
  1224. Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats
  1225. Berberine ameliorates high glucose-induced cardiomyocyte injury via AMPK signaling activation to stimulate mitochondrial biogenesis and restore autophagic …
  1226. Casticin suppresses the carcinogenesis of small cell lung cancer H446 cells through activation of AMPK/FoxO3a signaling
  1227. Rhus verniciflua and Eucommia ulmoides Protects Against High-Fat Diet-Induced Hepatic Steatosis by Enhancing Anti-Oxidation and AMPK Activation
  1228. Activation of AMPK by Buddleja officinalis Maxim. Flower Extract Contributes to Protecting Hepatocytes from Oxidative Stress
  1229. Consequences of AMPK activation
  1230. Elimination of cancer stem cells and reactivation of latent HIV-1 via AMPK activation: Common mechanism of action linking inhibition of tumorigenesis and the …
  1231. The Std1 activator of the Snf1/AMPK kinase controls glucose response in yeast by a regulated protein aggregation
  1232. Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome?
  1233. Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis
  1234. Inhibition of JNK and activation of the AMPK-Nrf2 axis by corosolic acid suppress osteolysis and oxidative stress
  1235. Anti-obesity effects of Spirulina maxima in high fat diet induced obese rats via the activation of AMPK pathway and SIRT1
  1236. Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway
  1237. Monounsaturated fatty acids impede inflammation partially through activation of AMPK
  1238. miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling
  1239. DMC (2′, 4′-dihydroxy-6′-methoxy-3′, 5′-dimethylchalcone) improves glucose tolerance as a potent AMPK activator
  1240. Perioperative oral supplementation with fish oil promotes liver regeneration following partial hepatectomy in mice via AMPK activation
  1241. Antihypertensive peptide purified from Styela clava flesh tissue stimulates glucose uptake through AMP-activated protein kinase (AMPK) activation in skeletal muscle …
  1242. Isoorientin ameliorates APAP-induced hepatotoxicity via activation Nrf2 antioxidative pathway: The involvement of AMPK/Akt/GSK3β
  1243. Bound phenolics from fresh lotus seeds exert anti-obesity effects in 3T3-L1 adipocytes and high-fat diet-fed mice by activation of AMPK
  1244. SIRT1 activation promotes β-cell regeneration by activating endocrine progenitor cells via AMPK signaling-mediated fatty acid oxidation
  1245. Berberine improves cognitive deficiency and muscular dysfunction via activation of the AMPK/SIRT1/PGC-1a pathway in skeletal muscle from naturally aging rats
  1246. Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-κB/NLRP3 inflammasome activation via the AMPK/SIRT1 …
  1247. Organoseleno cytostatic derivatives: Autophagic cell death with AMPK and JNK activation
  1248. AICAR-dependent activation of AMPK kinase is not accompanied by G1/S block in mouse embryonic stem cells
  1249. Activation of CaMKKβ-AMPK-mTOR pathway is required for autophagy induction by β, β-dimethylacrylshikonin against lung adenocarcinoma cells
  1250. Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling
  1251. Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) α1
  1252. Rapamycin inhibits activation of AMPK-mTOR signaling pathway-induced Alzheimer’s disease lesion in hippocampus of rats with type 2 diabetes mellitus
  1253. The natural flavone acacetin confers cardiomyocyte protection against hypoxia/reoxygenation injury via AMPK-mediated activation of Nrf2 signaling pathway
  1254. Deficiency in the anti‐aging gene Klotho promotes aortic valve fibrosis through AMPK α‐mediated activation of RUNX 2
  1255. … enhances the anti-cancerous effect of imatinib on human acute monocytic leukemia via the induction of autophagy-related apoptosis through AMPK activation
  1256. Antidiabetic effect of tibetan medicine Tang-Kang-Fu-San in db/db mice via activation of PI3K/Akt and AMPK pathways
  1257. Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function
  1258. … exercise preconditioning promotes autophagy against exhaustive exercise-induced myocardial injury through the activation of the AMPK-mTOR-ULK1 pathway
  1259. Inositol-requiring enzyme 1-dependent activation of AMPK promotes Brucella abortus intracellular growth
  1260. Artemether Activation of AMPK/GSK3β(ser9)/Nrf2 Signaling Confers Neuroprotection towards β-Amyloid-Induced Neurotoxicity in 3xTg Alzheimer’s Mouse …
  1261. … in mediating mitochondrial stress, energy imbalance, and sequential activation of autophagy and apoptosis in mouse Sertoli TM4 cells: possible role of AMPK/ULK1 …
  1262. Upregulation of microRNA-335-5p reduces inflammatory responses by inhibiting FASN through the activation of AMPK/ULK1 signaling pathway in a septic mouse …
  1263. Metabolic reprogramming by the excessive AMPK activation exacerbates antigen-specific memory CD8+ t cell differentiation after acute lymphocytic …
  1264. … inflammation-induced apoptosis in human umbilical vein endothelial cells via suppression of Ca2+-XO-ROS-Drp1-mitochondrial fission axis by activation of AMPK …
  1265. Identification of AMPK activator from twelve pure compounds isolated from Aralia Taibaiensis: implication in antihyperglycemic and hypolipidemic activities
  1266. Identification of direct activator of adenosine monophosphate-activated protein kinase (AMPK) by structure-based virtual screening and molecular docking approach
  1267. Blockade of MerTK activation by AMPK inhibits RPE cell phagocytosis
  1268. Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway
  1269. New synthetic AICAR derivatives with enhanced AMPK and ACC activation
  1270. … esters exert potential antidiabetic effects on glucose and lipid metabolism in cultured murine insulin-sensitive cells through mechanisms implicating activation of AMPK
  1271. The orphan nuclear receptor NR4A1 promotes FcεRI‐stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis
  1272. Sipjeondaebo-tang Alleviates Oxidative Stress-Mediated Liver Injury through Activation of the CaMKK2-AMPK Signaling Pathway
  1273. Fucosterol inhibits adipogenesis through the activation of AMPK and Wnt/β-catenin signaling pathways
  1274. Terpenoids: An activator of “fuel-sensing enzyme AMPK” with special emphasis on antidiabetic activity
  1275. Acute activation of endothelial AMPK surprisingly inhibits endothelium‐dependent hyperpolarization‐like relaxations in rat mesenteric arteries
  1276. The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation …
  1277. Eliciting α7‐nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling
  1278. 2-[2-(4-(trifluoromethyl) phenylamino) thiazol-4-yl] acetic acid (Activator-3) is a potent activator of AMPK
  1279. Mitochondrial dysfunction and apoptosis are attenuated on κ-opioid receptor activation through AMPK/GSK-3β pathway after myocardial ischemia and reperfusion
  1280. Phytol stimulates the browning of white adipocytes through the activation of AMP-activated protein kinase (AMPK) α in mice fed high-fat diet
  1281. GPR40 receptor activation promotes tight junction assembly in airway epithelial cells via AMPK-dependent mechanisms
  1282. Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through activation of AMPK signaling pathway
  1283. Activation of AMPK by OSU53 protects spinal cord neurons from oxidative stress
  1284. Erratum: A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3.
  1285. Ulmus macrocarpa Hance modulates lipid metabolism in hyperlipidemia via activation of AMPK pathway
  1286. Reduction of aging-induced oxidative stress and activation of autophagy by bilberry anthocyanin supplementation via the AMPK–mTOR signaling pathway in aged …
  1287. Impaired myocardial MIF/AMPK activation aggravates myocardial ischemia reperfusion injury in high-fat diet-induced obesity
  1288. Shengmai Injection Suppresses Angiotensin II-Induced Cardiomyocyte Hypertrophy and Apoptosis via Activation of the AMPK Signaling Pathway Through …
  1289. Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue
  1290. 4‐O‐methylhonokiol protects against diabetic cardiomyopathy in type 2 diabetic mice by activation of AMPK‐mediated cardiac lipid metabolism improvement
  1291. 4-O-methylhonokiol ameliorates type 2 diabetes-induced nephropathy in mice likely by activation of AMPK-mediated fatty acid oxidation and Nrf2-mediated anti …
  1292. Leptin Effect on Acetylation and Phosphorylation of Pgc1α in Muscle Cells Associated With Ampk and Akt Activation in High‐Glucose Medium
  1293. Bempedoic acid. ATP-citrate lyase inhibitor, AMPK activator, Treatment of hypercholesterolemia
  1294. Natural activators of adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) and their pharmacological activities
  1295. SIRT3-AMPK activation by nitrite and metformin improves hyperglycemia and normalizes pulmonary hypertension associated with heart failure with preserved …
  1296. Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling
  1297. Chitooligosaccharide inhibits cyst formation and enlargement through calcium restoration and AMPK activation
  1298. Activation of AMPK for a break in hepatic lipid accumulation and circulating cholesterol
  1299. A novel peptide suppresses adipogenic differentiation through activation of the AMPK pathway
  1300. Glucagon attenuates lipid accumulation in cow hepatocytes through AMPK signaling pathway activation
  1301. Annexin A1 drives macrophage skewing towards a resolving phenotype to accelerate the regeneration of muscle injury through AMPK activation
  1302. Excessive nNOS/NO/AMPK signaling activation mediated by the blockage of the CBS/H2S system contributes to oxygen‑glucose deprivation‑induced …
  1303. (−)-Hydroxycitric acid suppresses lipid droplet accumulation and accelerates energy metabolism via activation of the adiponectin-AMPK signaling pathway in broiler …
  1304. Berberine alleviates oxidized low‐density lipoprotein‐induced macrophage activation by downregulating galectin‐3 via the NF‐κB and AMPK signaling pathways
  1305. Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway
  1306. … of Velvet Antler (Cervus elaphus) against Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting MAPK/NF-κB Activation and Inducing AMPK …
  1307. Region-specific activation of the AMPK system by cocaine: The role of D1 and D2 receptors
  1308. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with …
  1309. Activation of AMPK/MnSOD signaling mediates anti-apoptotic effect of hepatitis B virus in hepatoma cells
  1310. Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway
  1311. microRNA-300/NAMPT regulates inflammatory responses through activation of AMPK/mTOR signaling pathway in neonatal sepsis
  1312. Activation of AMPK stimulates neurotensin secretion in neuroendocrine cells
  1313. … -protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of …
  1314. Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways
  1315. Alcohol consumption promotes colorectal carcinoma metastasis via a CCL5-induced and AMPK-pathway-mediated activation of autophagy
  1316. Halofuginone ameliorates inflammation in severe acute hepatitis B virus (HBV)-infected SD rats through AMPK activation
  1317. Metformin protects PC12 cells and hippocampal neurons from H2O 2‐induced oxidative damage through activation of AMPK pathway
  1318. Metabolic stress-induced activation of AMPK and inhibition of constitutive phosphoproteins controlling smooth muscle contraction: evidence for smooth …
  1319. Induction of autophagy following TTFields application serves as a survival mechanism mediated by AMPK activation
  1320. LKB1 promotes radioresistance in esophageal cancer cells exposed to radiation, by suppression of apoptosis and activation of autophagy via the AMPK …
  1321. The influence of AICAR-direct activator of AMP-activated protein kinase (AMPK)-on liver proteome in apoE-knockout mice
  1322. Methyleugenol protects against t-BHP-triggered oxidative injury by induction of Nrf2 dependent on AMPK/GSK3β and ERK activation
  1323. Fake inhibitors: AMPK activation trumps inhibition
  1324. Selenadiazole derivatives antagonize hyperglycemia-induced drug resistance in breast cancer cells by activation of AMPK pathways
  1325. Involvement of mTOR and regulation by AMPK in early iodine deficiency-induced thyroid microvascular activation
  1326. Hovenia Dulcis Extract Reduces Lipid Accumulation in Oleic Acid‐Induced Steatosis of Hep G2 Cells via Activation of AMPK and PPARα/CPT‐1 Pathway and in …
  1327. Effect of resistance exercise under conditions of reduced blood insulin on AMPKα Ser485/491 inhibitory phosphorylation and AMPK pathway activation
  1328. Trypsin-treated β-lactoglobulin improves glucose tolerance in C57BL/6 Mice by enhancing AMPK activation and glucose uptake in hepatocytes
  1329. AMPK activator acadesine fails to alleviate isoniazid‐caused mitochondrial instability in HepG2 cells
  1330. Quercetin confers protection of murine sepsis by inducing macrophage M2 polarization via the TRPM2 dependent calcium influx and AMPK/ATF3 activation
  1331. AMPK Activation of Flavonoids from Psidium guajava Leaves in L6 Rat Myoblast Cells and L02 Human Hepatic Cells
  1332. Intact cell assays to monitor AMPK and determine the contribution of the AMP-binding or ADaM sites to activation
  1333. In vitro progesterone production by luteinized human mural granulosa cells is modulated by activation of AMPK and cause of infertility
  1334. DNA-PKcs-mediated phosphorylation of AMPKγ1 regulates lysosomal AMPK activation by LKB1
  1335. Sheng-jiang powder ameliorates obesity-induced pancreatic inflammatory injury via stimulating activation of the AMPK signalling pathway in rats
  1336. … cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in high-fat …
  1337. Ethanol extract of Kalopanax septemlobus leaf induces caspase-dependent apoptosis associated with activation of AMPK in human hepatocellular carcinoma …
  1338. Procyanidin promotes translocation of glucose transporter 4 in muscle of mice through activation of insulin and AMPK signaling pathways
  1339. 3-Chloro-4, 5-dihydroxybenzaldehyde inhibits adipogenesis in 3T3-L1 adipocytes by regulating expression of adipogenic transcription factors and AMPK activation
  1340. The tiliroside derivative, 3-O-[(E)-(2-oxo-4-(p-tolyl) but–3–en–1–yl] kaempferol produced inhibition of neuroinflammation and activation of AMPK and Nrf2/HO-1 …
  1341. FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway
  1342. Epe1 contributes to activation of AMPK by promoting phosphorylation of AMPK alpha subunit, Ssp2
  1343. Compound C enhances tau phosphorylation at Serine396 via PI3K activation in an AMPK and rapamycin independent way in differentiated SH-SY5Y cells
  1344. Galactomannan pentasaccharide produced from copra meal enhances tight junction integration of epithelial tissue through activation of AMPK
  1345. QSP modeling of liver AMPK activation using NAFLDsym is predicted to reduce steatosis in NAFLD patients
  1346. Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells
  1347. Activation of AMPK alleviates cardiopulmonary bypass‐induced cardiac injury via ameliorating acute cardiac glucose metabolic disorder
  1348. Biophysical Interactions of Direct AMPK Activators
  1349. An antioxidant role by minocycline via enhancing the activation of LKB1/AMPK signaling in the process of cerebral ischemia injury
  1350. AICAR-mediated AMPK activation induces protective innate responses in bacterial endophthalmitis
  1351. Anti-malarial Drugs Reduce Vascular Smooth Muscle Cell Proliferation via Activation of AMPK and Inhibition of Smad3 Signaling
  1352. 13-Methylberberine reduces HMGB1 release in LPS-activated RAW264. 7 cells and increases the survival of septic mice through AMPK/P38 MAPK activation
  1353. … stress, mitochondrial dysfunction and endoplasmic reticulum stress in retinal pigment epithelial cells via triggering Ca2+/CaMKII-dependent activation of AMPK
  1354. Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity
  1355. mTOR activation due to APPL1 deficiency exacerbates hyperalgesia via Rab5/Akt and AMPK signaling pathway in streptozocin-induced diabetic rats
  1356. Activation of adenosine monophosphate–activated protein kinase (AMPK) enhances energy metabolism, motility, and fertilizing ability of cryopreserved spermatozoa …
  1357. Red pepper seed inhibits differentiation of 3T3-L1 cells during the early phase of adipogenesis via the activation of AMPK
  1358. … via suppression of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation and oxidative stress in a AMPK-dependent manner after …
  1359. Oxidative stress and decreased mitochondrial superoxide dismutase 2 and peroxiredoxins 1 and 4 based mechanism of concurrent activation of AMPK and mTOR in …
  1360. … suppresses adipogenesis of 3 T3-L1 preadipocytes by inhibiting CCAAT/enhancer-binding protein β activation and AMPK-mediated mitotic clonal expansion
  1361. Retraction notice to: Resveratrol attenuates lipopolysaccharide-induced dysfunction of blood-brain barrier in endothelial cells via AMPK activation
  1362. Serum is not necessary for prior pharmacological activation of AMPK to increase insulin sensitivity of mouse skeletal muscle
  1363. Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling …
  1364. Oocyte activation and latent HIV-1 reactivation: AMPK as a common mechanism of action linking the beginnings of life and the potential eradication of HIV-1
  1365. In silico Analysis of AMP-activated Protein Kinase and Ligand-based Virtual Screening for Identification of Novel AMPK Activators
  1366. Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells
  1367. Induction of apoptosis by Moutan Cortex Radicis in human gastric cancer cells through the activation of caspases and the AMPK signaling pathway
  1368. Optimization of metabolic and renal clearance in a series of indole acid direct activators of 5′-adenosine monophosphate-activated protein kinase (AMPK)
  1369. … skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation
  1370. The effects of evodiamine on serum total cholesterol and triglyceride levels are associated with the activation of the AMPK signaling pathway in rats with hyperlipemia
  1371. Induction of apoptosis by Citrus unshiu peel in human breast cancer MCF-7 cells: involvement of ROS-dependent activation of AMPK
  1372. Ethanol Extract of Pinus koraiensis Leaf Ameliorates Alcoholic Fatty Liver via the Activation of LKB1–AMPK Signaling In Vitro and In Vivo
  1373. Activation of AMPK restricts Zika virus replication in endothelial cells by potentiating antiviral response and inhibiting viral-induced glycolysis
  1374. Cell-to-cell variability in AMPK activation reveals autonomous cycles in cellular energy balance
  1375. Rethinking the regulation of l-carnitine transport in skeletal muscle cells. Focus on “Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle …
  1376. Compound 13, an α1-selective small molecule activator of AMPK, potently inhibits melanoma cell proliferation
  1377. Preparation of benzofuran derivatives for use as AMPK activators
  1378. … metabolic stress-induced cardiac injury through improving insulin resistance (IR) injury and endoplasmic reticulum (ER) stress by promoting AMPK-alpha activation
  1379. Betaine promotes LKB1-AMPK activation inhibits UVB-mediated senescence of human epidermal keratinocytes through autophagy induction
  1380. … induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK)
  1381. The energy sensing LKB 1–AMPK α1 pathway regulates IGF 1 secretion and consequent activation of the IGF 1R–PKB pathway in primary hepatocytes
  1382. MicroRNA‐155 inhibition up‐regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate‐treated osteoporotic mice
  1383. Sestrin 2 attenuates rat hepatic stellate cell (HSC) activation and liver fibrosis via an mTOR/AMPK-dependent mechanism
  1384. AlterAtiOn Of CYP3A1 mrnA level in PrimArY rAt HePAtOCYtes in resPOnse tO AmPK ACtivAtOr AiCAr
  1385. PXL770, a novel direct AMPK activator, improves metabolic disorders in a diet-induced mice model of obesity and diabetes
  1386. Ethanol extracts of Mori folium inhibit adipogenesis through activation of AMPK signaling pathway in 3T3-L1 preadipocytes
  1387. Effect of Hugan Qingzhi tablets on AMPK pathway activation and NF-κB-p65 protein expression in the liver of rats with nonalcoholic fatty liver disease
  1388. The flavonoid derivative 4′-nitro-6-hydroxyflavone suppresses the activity of HNF4α and stimulates the degradation of HNF4α protein through the activation of AMPK
  1389. PP2A inhibition by LB-100 protects retinal pigment epithelium cells from UV radiation via activation of AMPK signaling
  1390. Protective effect of berberine on oleic acid-induced injury in human aortic endothelial cells via AMPK-eNOS activation.
  1391. … of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation
  1392. Activation of AMPK inhibits medulloblastoma cell growth and Gli1 activity
  1393. Maternal Erythrocyte ENT1-Mediated AMPK Activation and Oxygen Delivery: A Missing Component Counteracting Placental Hypoxia, Dysfunction, and Fetal …
  1394. CAMKK2‐dependent AMPK activation is required to drive cell cycle progression and hepatocyte proliferation after partial hepatectomy in the rat
  1395. … -3-carboxylic acid (PF-06409577) and related indole-3-carboxylic acid derivatives are direct activators of adenosine monophosphate-activated protein kinase (AMPK)
  1396. AMPK activation regulates LTBP4-dependent TGF-b1 secretion by pro-inflammatory macrophages and controls fibrosis in duchenne muscular dystrophy
  1397. FO081 metformin alleviates stroke severity in female mice with chronic kidney disease through AMPK activation and subsequent decrease of microglia/macrophages …
  1398. 4-Hydroxyisoleucine attenuates the inflammation-mediated insulin resistance by the activation of AMPK and suppression of SOCS-3 coimmunoprecipitation with both …
  1399. Research progress on AMPK activators from natural products
  1400. β-GPA: AN AMPK ACTIVATOR WITH POTENTIAL EFFECTS ON HEALTHSPAN AND FUNCTION
  1401. Metformin, an activator of AMPK, promotes the growth of hair follicles via AMPK/β-catenin signaling pathway
  1402. Antidiabetic activity of Callicarpa nudiflora extract in type 2 diabetic rats via activation of the AMPK-ACC pathway
  1403. Ampk Activation Decreases Expression Of Mir-130B In Endothelial Cells
  1404. Statins induce apoptosis in osteosarcoma cells by activation of Ampk and p38-MAPK via suppression of mevalonate pathway
  1405. AMPK activation in the treatment of liver disease
  1406. P01. 04 AMPK activation and glycolysis inhibition protect neural cells from glucose and oxygen restriction
  1407. Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats
  1408. Development of small molecule direct AMPK activators for the treatment of cancer
  1409. γ-tocotrienol induces mitophagy in breast cancer cells through activation of LKB1-AMPK pathway
  1410. The Role of AMPK Activation in the Attenuation of Chronic Pain
  1411. Pharmacological Activation of Ampk With a Direct Pan-ampk Activator Results in a Worsening of a Hf Phenotype in Mice
  1412. The hypoxic ventilatory response is facilitated by the activation of Lkb1-AMPK signalling pathways downstream of the carotid bodies
  1413. Deciphering the Mechanisms of AMPK Activation upon Anchorage-Deprivation
  1414. Paeonia japonica ameliorates oxidative stress-induced liver injury through activation of AMPK-mediated GSK3β
  1415. Anti-inflammatory Effect of AMPK Activators from Natural Products in RAW 264.7 Cell Model (P06-095-19)
  1416. Honokiol attenuates lipopolysaccharide-induced acute respiratory distress syndrome via activation of mitochondrion-dependent Sirt3/AMPK pathway
  1417. Activation of transient receptor potential vanilloid 4 impairs the dendritic arborization of newborn neurons in the hippocampal dentate gyrus through the AMPK …
  1418. Effect of AMPK activation on the related factors of vascular injury repair.
  1419. Extracellular calcium influx promotes antibacterial autophagy in Escherichia coli infected murine macrophages via CaMKKβ dependent activation of ERK1/2, AMPK …
  1420. Complement component C1q regulates AMPK and ERK1/2 activation in mouse and human macrophages
  1421. 12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway
  1422. AMPK Activators as Novel Drug Candidates for the Treatment of Inflammatory Bowel Diseases
  1423. … glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation
  1424. … of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/ULK1 signaling activation
  1425. Preclinical PET imaging of AMPK activation in rats
  1426. Left Ventricular Function in Heart Failure Can Be Improved by AMPK-Activation via Acrp30 Signaling
  1427. Energy Expenditure during Cell Spreading Induces AMPK Activation and Regulates the Mechanoresponse of Stem Cells
  1428. In vitro studies on anti-obesity activity of Korean Memilmuk through AMPK activation
  1429. Neurotensin increases breast cancer proliferation through activation of AMPK
  1430. AMPK Activation Improves Survivability after Toxic Gas Exposure
  1431. Response to ‘Antihyperalgesia effect of AMP-activated protein kinase (AMPK) activators in a mouse model of postoperative pain’
  1432. Research of phytochemical AMPK activators against obesity and development of dietary supplements
  1433. Coenzyme Q10 Attenuates High-fat Diet-induced Non-alcoholic Fatty Liver Disease Through Activation of AMPK Pathway (P06-060-19)
  1434. Preparation of isoindoline derivatives for use as AMPK activators
  1435. Detecting Novel Effects of Exercise or AMPK Activation in Human Skeletal Muscle
  1436. Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells
  1437. AMPK-activation reduces EDH-type relaxations in rat small arteries
  1438. AMPK activation protects photoreceptors from light-induced degeneration.
  1439. IMQ induced AMPK activation causes translation inhibition and apoptosis but not autophagy
  1440. AMPK Activation for the Treatment of Fuchs Endothelial Corneal Dystrophy
  1441. Investigating the effect of AMPK activation on T cell-mediated anti-tumour immunity
  1442. Effects of AMPK activation on insulin resistance and inflammatory factors in rats with chronic intermittent hypoxia
  1443. Exercise improves outcomes of surgery on fatty liver and can be substituted through AMPK activation–An experimental study
  1444. Research Article Synthesis and In Vitro AMPK Activation of Cycloalkyl/Alkarylbiguanides with Robust In Vivo Antihyperglycemic Action
  1445. Novel Dual MTOR Inhibitors/AMPK Activators Attenuate Doxorubicin-Induced Cardiotoxicity
  1446. A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3
  1447. … Into The Cardiovascular Disease (CVD) Phenotypes Underlying Increased Susceptibility To Cardiac Remodeling During Menopause With A Focus On AMPK Activator …
  1448. A New Synthetic FRET Sensor to Analyze Allosteric AMPK Activation and Cellular Energy State
  1449. Acute Stress Diminishes M‐Current in Corticotrophin‐Releasing Hormone Neurons through AMPK Activation
  1450. FND 4b decreases proliferation and increases apoptosis of triple negative breast cancer through AMPK activation
  1451. Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism
  1452. Ampk Activators Reduces Cigarette Smoke-Induced Inflammatory Responses And Elastase-Induced Mouse Emphysema
  1453. Hexokinase II Localization is Independent of AMPK Activation in HeLa Cells
  1454. Abstract LB-A02: AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells
  1455. AMPK activator alleviates TNF-α-induced fulminant liver injury in mice.
  1456. PXL770, a Novel Direct AMPK Activator, Inhibits Hepatic de novo Lipogenesis for the Treatment of Metabolic Disorders
  1457. AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
  1458. AMPK activator down-regulates the expression of tissue factor in fulminant hepatitis mice
  1459. Diet Control Diet to Achieve Euglycemia Induces Tau Hyperphosphorylation Via AMPK Activation in the Hippocampus of Diabetic Rats
  1460. Retraction: Berberine Improves Kidney Function in Diabetic Mice via AMPK Activation
  1461. A70 THE GOOD, THE BAD, AND THE UGLY OF AGING: Ampk Activators Reduces Cigarette Smoke-Induced Inflammatory Responses And Elastase-Induced Mouse …
  1462. Losartan inhibits LPS-induced GFAP expression via AMPK activation in mouse hippocampus
  1463. AMPK Activation by Zyflamend: A novel pathway regulating metabolism and growth in prostate cancer
  1464. NADPH Oxidase and Xanthine Oxidase Inhibition Attenuates the Activation of AMPK Signaling After a Single Bout of Endurance Exercise in Mouse Skeletal Muscle
  1465. Multiple AMPK activators inhibit L-Carnitine uptake in C2C12 skeletal muscle myotubes. 2
  1466. Hippocampal AMPK activation suppresses depressive-like behavior in olfactory bulbectomized mice
  1467. Evidence that the AMPK activator, Metformin, induced protection of the retina and RPE through metabolic reprogramming
  1468. Fructooligosaccharides induce tight junction assembly in intestinal epithelial cells via AMPK activation
  1469. AMPK-ARE ACTIVATORS OR INHIBITORS REQUIRED FOR CANCER TREATMENT?
  1470. Exogenous pyruvate potentiates mesodermal differentiation through AMPK activation in human embryonic stem cells
  1471. … -5H-thieno [3′, 2′: 3, 4] pyrido [1, 2-b] isoquinolines as novel adenosine 5′-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of …
  1472. γ-Tocotrienol negative modulation of the Warburg effect is mediated by the AMPK activation in malignant breast cancer cells
  1473. Capsaicin Targets Lipogenesis in HepG2 Cells Through AMPK Activation, AKT Inhibition and PPARs Regulation
  1474. Prior Treatment with the AMPK Activator AICAR Induces Subsequently Enhanced Glucose Uptake in Isolated Skeletal Muscles from Old Rats
  1475. Glucose consumption assay discovered a novel compound from natural product with beneficial effects on diabetic mice via AMPK activation
  1476. Recovery of Immune Homeostasis Via AMPK Activation in Spite of Parkin-Deficiency in Mice with Sepsis-Induced Immunosuppression
  1477. Divergent effects of DHA treatment and AMPK activation on protein synthesis rate and signaling in palmitate‐treated skeletal muscle
  1478. AMPK Activation in Human Skeletal Muscle Is Fiber Type-Specific following Acute High Intensity Interval Exercise
  1479. AMPK Activation by Acute Endurance Exercise Controls PPARβ/δ Expression through MEF2A
  1480. Cardiac myocyte-specific expression of beta3-adrenergic receptors sustains AMPK activation and glucose uptake while reducing hypertrophy following pressure …
  1481. Regulation of AMPK Activation and Its Role in Cell Death Induced by Glucose Starvation in LKB1-Mutant Human Lung Cancer Cells
  1482. Inhibition of H1299 Human Lung Cancer Cell Proliferation and Survival by Carnosic Acid is Associated with Akt Inhibition and AMPK Activation.
  1483. Metformin, an AMPK Activator, Inhibits Radiation-Induced Skin Damage Via the FOXO3
  1484. The AMPK Activators AICAR and A769662 Reduce Relaxations of Rat Superior Mesenteric Arteries attributable to Endothelium‐dependent Hyperpolarization
  1485. Withdrawn: Safranal induces autophagy by AMPK activation and protects neurons against amyloid beta in Alzheimer’s disease
  1486. AMPK-activation reduces relaxations attributable to the opening of potassium channels in endothelial and smooth muscle cells of the rat superior mesenteric artery
  1487. AMPK activation by P2X7 through ROS-CaMKK pathway regulates mitophagy and lysosomal biogenesis in macrophages
  1488. Red Ginseng Alters Lipid Metabolism through AMPK Activation in Liver and Adipose Tissues of High-Fat Diet-Fed Mice
  1489. Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells
  1490. Protection of berberine on intestinal mucosa following autologous orthotropic liver transplantation and its correlationship with p-AMPK activation and p-mTOR …
  1491. Flufenamic Acid Prevents Vibrio cholerae El Tor Variant‐Induced Diarrhea via AMPK Activation and Suppression of NF‐κB‐Mediated Inflammation
  1492. Gallotannin induces senescence and autophagy leading to cell death via SIRT1 inhibition and AMPK activation in hepatocellular carcinoma cells
  1493. Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway
  1494. Activation of AMPK by Metformin Attenuates Marginal Graft Injury via Promoting Mitochondrial Biogenesis
  1495. Research Article Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells
  1496. Tamoxifen Sensitizes Gallbladder Cancer to Cisplatin Resistance by Impaired Glucose Metabolism via Activation of AMPK Signaling
  1497. (301) Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the transition to a chronic pain state
  1498. Transient Activation of AMPK Prior to Cardiac Pressure Overload Alleviates Fibrotic Accumulation and Functional Decline
  1499. Activation of AMPK Inhibits Hyperpolarization-Mediated Relaxations in Rat Superior Mesenteric Arteries
  1500. Berberine protected RPE cells from H2O2 induced oxidative stress via the activation of the AMPK pathway
  1501. Berberine protected RPE cells from H2O2 induced cell injury via the activation of the AMPK pathway
  1502. Abeta42 oligomers trigger synaptic loss through AMPK-dependent activation of mitochondrial fission and mitophagy
  1503. Postexercise improvement in glucose uptake occurs concomitant with greater γ3-AMPK 1 activation and AS160 phosphorylation in rat skeletal muscle 2
  1504. Activation of AMPK pathway is involved in the protection of Metformin on PC12 cells and hippocampal neurons against H2O2-induced oxidative damage
  1505. Metformin Displays Cardioprotection in δ-sarcoglycan Deficiency Induced Cardiomyopathy Through Autophagic Activation via AMPK-mTOR Pathway
  1506. Correction to: A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization by Wang Y, Huang Y, Xu Y, Ruan W …
  1507. The combination of Korean red ginseng and Glycyrrhiza glabra L. extracts enhances AMPK pathway activation in C57BL/6J obese mice
  1508. The Natural Flavone Acacetinslows the Development of Atherosclerosis by Sirt3-Mediated Activation of AMPK Signaling Pathway in Diabetic ApoE Null Mice
  1509. Induction of Apoptosis and Autophagy by Resveratrol via Activation of AMPK Pathway in 5-Fluorouracil-Resistant Colon Cancer Cells
  1510. GW28-e0091 CTRP9 Alleviates Hypoxia-Induced Cardiomyocytes Injury by Inducing Autophagy Via the AMPK Signaling Activation
  1511. Activation of AMPK‐FoxO3a pathway mediated autophagy inhibits fibroblast‐myofibroblast differentiation in pulmonary fibrosis
  1512. THU0053 Selective activation of an AMPK-CREB-NRF2-dependent pathway by celecoxib induces vasculoprotective genes and mitigates against cardiovascular risk
  1513. Pentamethylquercetin counteracts obesity and drives brown fat-like phenotype through AMPK-mediated activation of PGC-1 alpha/FNDC5 pathway in muscle
  1514. Artemisinin protected human SH-SY5Y and hippocampal neurons from hydrogen peroxide (H2O2)-induced oxidative damage through the activation of the AMPK …
  1515. Oleuropein ameliorates palmitate-induced insulin resistance by increasing Glut4 translocation through activation of AMPK
  1516. Autophagy Activation by Leptin Mediates the Growth of Breast Cancer Cells via Estrogen Receptor Signaling: Involvement of AMPK/FoxO3A Axis
  1517. Gamma Tocotrienol Suppresses NLRP3 Inflammasome by Dual Mechanism of A20‐mediated Priming Inhibition and AMPK/autophagy Axis Activation
  1518. LKB1/AMPK/M-TOR response to ischemia in high metabolic rate tissues: A comparison between the brain, heart, kidney and liver intracellular metabolic axis activation …
  1519. … effect of Metformin against H2O2-induced oxidative damage in human retinal pigment epithelial (RPE) cells through activation of AMPK/mTOR/Autophagy pathway
  1520. Artemether Activation of AMPK/GSK3β (ser9)/Nrf2 Signaling Confers Neuroprotection towards β-Amyloid-Induced Neurotoxicity in 3xTg Alzheimer’s Mouse Model
  1521. Genetic Deletion of Elovl6 in Cardiac Myocytes Suppresses Pressure Overload-Induced Cardiac Hypertrophy and Remodeling Through Activation of AMPK/KLF4 …
  1522. AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
  1523. 516-P: Preventive Effect of Sulforaphane on Type 2 Diabetes-Induced Diabetic Nephropathy via AMPK-Mediated Activation of Glucose/Lipid Metabolism and Nrf2 …
  1524. 613-P: Preventive Effect of Sulforaphane on Type 2 Diabetes-Induced Diabetic Cardiomyopathy via AMPK-Mediated Activation of Glucose/Lipid Metabolism and Nrf2 …
  1525. Skeletal Muscle LKB1/SIRT3-AMPK-GLUT4 Activation by Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary …
  1526. … enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as dsRNA …
  1527. The circular RNA NRIP1 plays oncogenic roles by targeting miR-505 through the activation of AMPK and PI3K/AKT/mTOR pathways in the renal carcinoma cell lines
  1528. Stromal Cell-derived Factor-1 Prevents From Diabetic Cardiomyopathy via Cxcr7/ampk-mediated Nrf2 Activation in Type 2 Diabetic Mice
  1529. 1822: ACTIVATION OF STAT3 REDUCES SPLANCHNIC ISCHEMIA/REPERFUSION INJURY IN AN AMPK-INDEPENDENT MANNER
  1530. Mitochondrial adenylate kinase 4 regulates dual AMPK and mTORC1 activation
  1531. MP39-18 MITOCHONDRIA FUNCTION CHANGE AND ACTIVATION OF AMPK-PGC1? PATHWAY THROUGH INDUCTION OF CLEAR CYTOPLASM IN RENAL CELL …
  1532. 451-P: SGLT2 Inhibitor Protects Cardiomyocytes against Palmitate-Induced Lipotoxicity by Increasing Activation of AMPK and Lipid Oxidations
  1533. Regulatation of Type 2 Diabetes Mellitus-Induced Non-Alcoholic Fatty Liver Disease through Activation of AMPK and PPAR-α by Black Ginseng
  1534. AICAr, a widely used AMPK activator with important AMPK-independent effects: a systematic review
  1535. The bewildering effect of AMPK activators in Alzheimer’s disease: review of the current evidence
  1536. New insights into activation and function of the AMPK
  1537. Energy-stress-mediated AMPK activation inhibits ferroptosis
  1538. Factors influencing AMPK activation during cycling exercise: a pooled analysis and meta-regression
  1539. AMPK in microvascular complications of diabetes and the beneficial effects of AMPK activators from plants
  1540. The role of AMPK activation for cardioprotection in doxorubicin-induced cardiotoxicity
  1541. ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation
  1542. Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
  1543. The metformin mechanism on gluconeogenesis and AMPK activation: the metabolite perspective
  1544. Empagliflozin protects heart from inflammation and energy depletion via AMPK activation
  1545. Direct AMPK activation corrects NASH in rodents through metabolic effects and direct action on inflammation and fibrogenesis
  1546. Natural AMPK activators in cardiovascular disease prevention
  1547. AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth
  1548. Metformin, an AMPK activator, inhibits activation of FLSs but promotes HAPLN1 secretion
  1549. Targeting breast cancer and their stem cell population through AMPK activation: Novel insights
  1550. Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation
  1551. AMPK activator O304 protects against kidney aging through promoting energy metabolism and autophagy
  1552. AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells
  1553. Activation of AMPK under hypoxia: many roads leading to Rome
  1554. Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPK activation: In vitro and in vivo studies
  1555. AMPK activators for the prevention and treatment of neurodegenerative diseases
  1556. AMPK activation protects against prostate cancer by inducing a catabolic cellular state
  1557. Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation
  1558. IQGAP1 binds AMPK and is required for maximum AMPK activation
  1559. Licochalcone d ameliorates oxidative stress-induced senescence via ampk activation
  1560. Stigmasterol attenuates inflammatory response of microglia via NF-κB and NLRP3 signaling by AMPK activation
  1561. Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and …
  1562. Neuroprotective and vision‐protective effect of preserving ATP levels by AMPK activator
  1563. Ginsenoside-Rg2 affects cell growth via regulating ROS-mediated AMPK activation and cell cycle in MCF-7 cells
  1564. Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
  1565. AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner
  1566. AdipoRon induces AMPK activation and ameliorates Alzheimer’s like pathologies and associated cognitive impairment in APP/PS1 mice
  1567. Ganoderma lucidum Extract Reduces Insulin Resistance by Enhancing AMPK Activation in High-Fat Diet-Induced Obese Mice
  1568. The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP+
  1569. AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes
  1570. Carnosol inhibits cerebral ischemia-reperfusion injury by promoting AMPK activation
  1571. Ginsenoside-Rg2 exerts anti-cancer effects through ROS-mediated AMPK activation associated mitochondrial damage and oxidation in MCF-7 cells
  1572. Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation
  1573. AMPK activation reverts mouse epiblast stem cells to naive state
  1574. Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
  1575. TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α …
  1576. Mechanism of activation of AMPK by cordycepin
  1577. The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS …
  1578. A novel AMPK activator shows therapeutic potential in hepatocellular carcinoma by suppressing HIF1α‐mediated aerobic glycolysis
  1579. An AMPK activator as a therapeutic option for congenital nephrogenic diabetes insipidus
  1580. Total flavonoids in Epimedium koreanum Nakai alleviated chronic renal failure via promoting AMPK activation
  1581. AMPK Activation: Respiratory Panacea?
  1582. Dietary nucleotides alleviate hepatic lipid deposition via exogenous AMP-mediated AMPK activation in zebrafish
  1583. AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer
  1584. Effects of vitamin D supplementation on adipose tissue inflammation and NF-κB/AMPK activation in obese mice fed a high-fat diet
  1585. AMPK activator O304 improves metabolic and cardiac function, and exercise capacity in aged mice
  1586. Metformin alleviates oxidative stress‐induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration
  1587. Sargassum thunbergii Extract Attenuates High-Fat Diet-Induced Obesity in Mice by Modulating AMPK Activation and the Gut Microbiota
  1588. Metformin suppresses cancer stem cells through AMPK activation and inhibition of protein prenylation of the mevalonate pathway in colorectal cancer
  1589. Energy-stress-mediated AMPK activation promotes GPX4-dependent ferroptosis through the JAK2/STAT3/P53 axis in renal cancer
  1590. Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation
  1591. Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease model via AMPK activation
  1592. Aucubin prevents steroid‐induced osteoblast apoptosis by enhancing autophagy via AMPK activation
  1593. Geniposide improves diabetic nephropathy by enhancing ULK1-mediated autophagy and reducing oxidative stress through AMPK activation
  1594. Knockdown of LKB1 sensitizes endometrial cancer cells via AMPK activation
  1595. Increasing SnRK1 activity with the AMPK activator A-769662 accelerates seed germination in rice
  1596. Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells
  1597. Selective AMPK activator leads to unfolded protein response downregulation and induces breast cancer cell death and autophagy
  1598. PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1
  1599. TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy
  1600. Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer
  1601. AMPK activation does not enhance autophagy in neurons in contrast to MTORC1 inhibition: different impact on β-amyloid clearance
  1602. Energy deprivation-induced AMPK activation inhibits milk synthesis by targeting PrlR and PGC-1α
  1603. Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation
  1604. p-Coumaric Acid Enhances Hypothalamic Leptin Signaling and Glucose Homeostasis in Mice via Differential Effects on AMPK Activation
  1605. CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer
  1606. MK8722, an AMPK activator, inhibiting carcinoma proliferation, invasion and migration in human pancreatic cancer cells
  1607. Papain ameliorates lipid accumulation and inflammation in high-fat diet-induced obesity mice and 3T3-L1 adipocytes via AMPK activation
  1608. Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization
  1609. Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death
  1610. Irisin induces trophoblast differentiation via AMPK activation in the human placenta
  1611. Shikonin attenuates hepatic steatosis by enhancing beta oxidation and energy expenditure via AMPK activation
  1612. Pan-AMPK activator O304 prevents gene expression changes and remobilisation of histone marks in islets of diet-induced obese mice
  1613. AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
  1614. Evaluating the impact of AMPK activation, a target of metformin, on risk of cardiovascular diseases and cancer in the UK Biobank: a Mendelian randomisation …
  1615. Effects of the peripheral CB1 receptor antagonist JD5037 in mono—and polytherapy with the AMPK activator metformin in a monocrotaline-induced rat model …
  1616. Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions
  1617. Obligatory Role of AMPK Activation and Antioxidant Defense Pathway in the Regulatory Effects of Metformin on Cellular Protection and Prevention of Lens Opacity
  1618. In Silico and In Vitro Approach to Assess Direct Allosteric AMPK Activators from Nature
  1619. AMPK activators have compound and concentration‐specific effects on brain metabolism
  1620. Piperlongumine synergistically enhances the antitumour activity of sorafenib by mediating ROS-AMPK activation and targeting CPSF7 in liver cancer
  1621. Antitumor effect of morusin via G1 arrest and antiglycolysis by AMPK activation in hepatocellular cancer
  1622. The role of AMPK signaling in brown adipose tissue activation
  1623. … bayberry leaves reduce obesity and associated metabolic disorders in high-fat diet-induced obese mice through a combination of AMPK activation and an alteration …
  1624. TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise
  1625. GAS6/Axl is associated with AMPK activation and attenuates H2O2-induced oxidative stress
  1626. Rice bran phenolic extract supplementation ameliorates impaired lipid metabolism in high-fat-diet fed mice through AMPK activation in liver
  1627. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495
  1628. AMPK activation protects astrocytes from hypoxia‑induced cell death
  1629. Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer
  1630. Mogroside V protects against hepatic steatosis in mice on a high-fat diet and LO2 cells treated with free fatty acids via AMPK activation
  1631. Carnosic acid prevented olanzapine-induced metabolic disorders through AMPK activation
  1632. TFAM depletion overcomes hepatocellular carcinoma resistance to doxorubicin and sorafenib through AMPK activation and mitochondrial dysfunction
  1633. … X Receptor Overexpression Decreases the Migration, Invasion and Angiogenesis of Human Bladder Cancers via AMPK Activation and Cholesterol Biosynthesis …
  1634. Orchestrated action of AMPK activation and combined VEGF/PD-1 blockade with lipid metabolic tunning as multi-target therapeutics against ovarian cancers
  1635. Nifedipine-induced AMPK activation alleviates senescence by increasing autophagy and suppressing of Ca2+ levels in vascular smooth muscle cells
  1636. Berbamine induced AMPK activation regulates mTOR/SREBP-1c axis and Nrf2/ARE pathway to allay lipid accumulation and oxidative stress in steatotic HepG2 cells
  1637. The protein tyrosine phosphatase PTP-PEST mediates hypoxia-induced endothelial autophagy and angiogenesis via AMPK activation
  1638. AMPK activation restores salivary function following radiation treatment
  1639. AMPK activation alleviates myocardial ischemia-reperfusion injury by regulating Drp1-mediated mitochondrial dynamics
  1640. Ginger extract controls mTOR-SREBP1-ER stress-mitochondria dysfunction through AMPK activation in obesity model
  1641. The combination of cinnamaldehyde and kaempferol ameliorates glucose and lipid metabolism disorders by enhancing lipid metabolism via AMPK activation
  1642. Acute, next‐generation AMPK activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle
  1643. Red Pepper Seeds Inhibit Hepatic Lipid Accumulation by Inducing Autophagy via AMPK Activation
  1644. Catalpol-induced AMPK activation alleviates cisplatin-induced nephrotoxicity through the mitochondrial-dependent pathway without compromising its …
  1645. … Mix of Polyphenols and Micronutrients Reduces Adipogenesis and Promotes White Adipose Tissue Browning via UCP1 Expression and AMPK Activation
  1646. Trans‐gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation
  1647. Adiponectin restrains ILC2 activation by AMPK-mediated feedback inhibition of IL-33 signaling
  1648. Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function
  1649. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I
  1650. Diosmetin alleviates hypoxia‑induced myocardial apoptosis by inducing autophagy through AMPK activation
  1651. Metformin-induced AMPK activation promotes cisplatin resistance through PINK1/Parkin dependent mitophagy in gastric cancer
  1652. … inhibits adipogenesis in 3T3-L1 adipocytes by regulating adipogenic transcription factors and adenosine monophosphate-activated protein kinase (AMPK) activation
  1653. AMPK activator AICAR in combination with anti-mouse IL10 mAb restores the functionality of intra-tumoral Tfh cells in the 4T1 mouse model
  1654. Eupatilin suppresses pancreatic cancer cells via glucose uptake inhibition, AMPK activation, and cell cycle arrest
  1655. Acute nicotine treatment alleviates LPS-induced impairment of fear memory reconsolidation through AMPK activation and CRTC1 upregulation in hippocampus
  1656. Metformin limits osteoarthritis development and progression through activation of AMPK signalling
  1657. Identification of novel indole derivatives as highly potent AMPK activators with anti-diabetic profiles
  1658. Chronic AMPK Activation Reduces the Expression and Alters Distribution of Synaptic Proteins in Neuronal SH-SY5Y Cells
  1659. Maternal erythrocyte ENT1–mediated AMPK activation counteracts placental hypoxia and supports fetal growth
  1660. Anisomycin inhibits angiogenesis, growth, and survival of triple-negative breast cancer through mitochondrial dysfunction, AMPK activation, and mTOR inhibition
  1661. Sustained activation of AMPK enhances differentiation of human iPSC-derived cardiomyocytes via sirtuin activation
  1662. Higenamine attenuates doxorubicin-induced cardiac remodeling and myocyte apoptosis by suppressing AMPK activation
  1663. Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
  1664. AMPK activation in pregnant human myometrial arteries from high-altitude and intrauterine growth-restricted pregnancies
  1665. Anti-diabetic effects of linarin from Chrysanthemi Indici Flos via AMPK activation
  1666. LncRNA Chaer prevents cardiomyocyte apoptosis from acute myocardial infarction through AMPK activation
  1667. Prenylflavonoids from fruit of Macaranga tanarius promote glucose uptake via AMPK activation in L6 myotubes
  1668. Pre-clinical evidence that salinomycin is active against retinoblastoma via inducing mitochondrial dysfunction, oxidative damage and AMPK activation
  1669. Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 …
  1670. AMPK Activation Is Important for the Preservation of Insulin Sensitivity in Visceral, but Not in Subcutaneous Adipose Tissue of Postnatally Overfed Rat Model of …
  1671. AMPK S-sulfuration contributes to H2S donors-induced AMPK phosphorylation and autophagy activation in dopaminergic cells
  1672. … an Active Cyclopeptide Alleviates Dextran Sulfate Sodium‐Induced Colitis by Modulating Gut Microbiota and Repairing Intestinal Mucosal Barrier via AMPK Activation
  1673. Hypolipidemic effects of macadamia oil are related to AMPK activation and oxidative stress relief: In vitro and in vivo studies
  1674. Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer
  1675. AMPK activation is indispensable for the protective effects of caloric restriction on left ventricular function in postinfarct myocardium
  1676. Sleeve gastrectomy-induced AMPK activation attenuates diabetic cardiomyopathy by maintaining mitochondrial homeostasis via NR4A1 suppression in rats
  1677. Mineral trioxide aggregate‐induced AMPK activation stimulates odontoblastic differentiation of human dental pulp cells
  1678. … and glucose metabolism by glycosylated kaempferol rich roasted leaves of Lycium chinense via upregulating adiponectin and AMPK activation in obese mice …
  1679. AMPK activation by dietary AICAR affects the growth performance and glucose and lipid metabolism in juvenile grass carp
  1680. … component Moscatilin mitigates Glycation-mediated damages in an SH-SY5Y cell model of neurodegenerative diseases through AMPK activation and RAGE/NF-κ B …
  1681. Modeling Structure–Activity Relationship of AMPK Activation
  1682. Natural product mogrol attenuates bleomycin-induced pulmonary fibrosis development through promoting AMPK activation
  1683. N-butylidenephthalide ameliorates high-fat diet-induced obesity in mice and promotes browning through adrenergic response/AMPK activation in mouse beige …
  1684. Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation
  1685. Mitochondrial dysfunction, AMPK activation and peroxisomal metabolism: A coherent scenario for non-canonical 3-methylglutaconic acidurias
  1686. Metformin ameliorates chronic colitis in a mouse model by regulating interferon‐γ‐producing lamina propria CD4+ T cells through AMPK activation
  1687. Cardioprotective effects of melatonin against myocardial ischaemia/reperfusion injury: Activation of AMPK/Nrf2 pathway
  1688. Effective fraction from Simiao Wan prevents hepatic insulin resistant by inhibition of lipolysis via AMPK activation
  1689. AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3
  1690. Neuroprotective effect of IND1316, an indole-based AMPK activator, in animal models of Huntington disease
  1691. Increased oxidative stress contributes to enhance brain amyloidogenesis and blunts energy metabolism in sucrose-fed rat: Effect of AMPK activation
  1692. AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue
  1693. Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation
  1694. AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
  1695. Phthalide derivative CD21 alleviates cerebral ischemia-induced neuroinflammation: involvement of microglial M2 polarization via AMPK activation
  1696. Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation
  1697. Photobiomodulation reduces hepatic lipogenesis and enhances insulin sensitivity through activation of CaMKKβ/AMPK signaling pathway
  1698. AMPK activation alleviated DSS‐induced colitis by inhibiting ferroptosis
  1699. AMPK activation ameliorates fine particulate matter-induced hepatic injury
  1700. Rosmarinic acid improves boar sperm quality, antioxidant capacity and energy metabolism at 17 C via AMPK activation
  1701. Fluid flow-induced activation of subcellular AMPK and its interaction with FAK and Src
  1702. Glucose and Serum Deprivation Led to Altered Proliferation, Differentiation Potential and AMPK Activation in Stem Cells from Human Deciduous Tooth
  1703. AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic …
  1704. Dammarane-type triterpenoids from Gynostemma compressum XX Chen & DR Liang (Cucurbitaceae) and their AMPK activation effect in 3T3-L1 cells
  1705. Adiponectin facilitates postconditioning cardioprotection through both AMPK-dependent nuclear and AMPK-independent mitochondrial STAT3 activation
  1706. Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators
  1707. Tschimganidine reduces lipid accumulation through AMPK activation and alleviates high-fat diet-induced metabolic diseases
  1708. Adropin inhibited tilapia hepatic glucose output and triglyceride accumulation via AMPK activation
  1709. Francisella tularensis Exploits AMPK Activation to Harvest Host-Derived Nutrients Liberated from Host Lipolysis
  1710. Pharmacological and exercise‐induced activation of AMPK as emerging therapies for myotonic dystrophy type 1 patients
  1711. Activation of AMPK promotes maturation of cardiomyocytes derived from human induced pluripotent stem cells
  1712. Globular adiponectin ameliorates insulin resistance in skeletal muscle by enhancing the LKB1-mediated AMPK activation via SESN2
  1713. AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery
  1714. AMPK and its activator berberine in the treatment of neurodegenerative diseases
  1715. Selenium nanoparticles improve fish sperm quality by enhancing glucose uptake capacity via AMPK activation
  1716. FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination
  1717. AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation
  1718. Citrus peel extract ameliorates high-fat diet-induced NAFLD via activation of AMPK signaling
  1719. Pyrvinium treatment confers hepatic metabolic benefits via β-catenin downregulation and AMPK activation
  1720. Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis
  1721. The Impact of Genetically Proxied AMPK Activation, the Target of Metformin, on Functional Outcome Following Ischemic Stroke
  1722. Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice
  1723. … and ticagrelor have additive effects on the attenuation of the activation of the NLRP3 inflammasome and the progression of diabetic cardiomyopathy: An AMPK …
  1724. Resveratrol downregulates ENaCs through the activation of AMPK in human colon cancer cells
  1725. Activation of AMPK promotes cardiac differentiation by stimulating the autophagy pathway
  1726. Regulatory role of cardiomyocyte metabolism via AMPK activation in modulating atrial structural, contractile, and electrical properties following atrial fibrillation
  1727. AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to …
  1728. MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity
  1729. AMPK activation attenuates cancer-induced bone pain by reducing mitochondrial dysfunction-mediated neuroinflammation: AMPK activation attenuates bone …
  1730. Cordycepin enhances the chemosensitivity of esophageal cancer cells to cisplatin by inducing the activation of AMPK and suppressing the AKT signaling …
  1731. Icariin, the main prenylflavonoid of Epimedii Folium, ameliorated chronic kidney disease by modulating energy metabolism via AMPK activation
  1732. Impacts of altered exercise volume, intensity, and duration on the activation of AMPK and CaMKII and increases in PGC-1α mRNA
  1733. Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling
  1734. Paris saponin VII, a direct activator of AMPK, induces autophagy and exhibits therapeutic potential in non-small-cell lung cancer
  1735. … , attenuates obesity, non-alcoholic fatty liver, and insulin resistance Via inhibitions of pancreatic lipase, cAMP-dependent PDE activity, AMPK activation, and SOCS-3 …
  1736. The intraperitoneal administration of MOTS-c produces antinociceptive and anti-inflammatory effects through the activation of AMPK pathway in the mouse formalin …
  1737. Scopoletin increases glucose uptake through activation of PI3K and AMPK signaling pathway and improves insulin sensitivity in 3T3-L1 cells
  1738. Metformin-induced AMPK activation suppresses larval growth and molting probably by disrupting 20E synthesis and glycometabolism in fall webworm, Hyphantria …
  1739. Metformin inhibits abdominal aortic aneurysm formation through the activation of the AMPK/mTOR signaling pathway
  1740. Cordycepin protects against acute pancreatitis by modulating NF-κB and NLRP3 inflammasome activation via AMPK
  1741. Low-dose metformin and PEN2-dependent lysosomal AMPK activation: benefits outnumber side effects
  1742. Anti-inflammatory effects of vinpocetine in LPS-stimulated microglia via activation of AMPK
  1743. A novel zinc chelator, 1H10, ameliorates experimental autoimmune encephalomyelitis by modulating zinc toxicity and AMPK activation
  1744. Lower body weight in rats under hypobaric hypoxia exposure would lead to reduced right ventricular hypertrophy and increased AMPK activation
  1745. Metformin resensitizes sorafenib-resistant HCC cells through AMPK-dependent autophagy activation
  1746. Mitophagy: molecular mechanisms, new concepts on Parkin activation and the emerging role of AMPK/ULK1 Axis
  1747. Herbal Combination of Phyllostachys pubescens and Scutellaria baicalensis Inhibits Adipogenesis and Promotes Browning via AMPK Activation in 3T3-L1 …
  1748. KCNK3 inhibits proliferation and glucose metabolism of lung adenocarcinoma via activation of AMPK-TXNIP pathway
  1749. Activation of AMPK by triptolide alleviates nonalcoholic fatty liver disease by improving hepatic lipid metabolism, inflammation and fibrosis
  1750. Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD
  1751. ABHD5 suppresses cancer cell anabolism through lipolysis-dependent activation of the AMPK/mTORC1 pathway
  1752. Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans
  1753. Apigenin alleviates renal fibroblast activation through AMPK and ERK signaling pathways in vitro
  1754. Glucose-6-phosphate dehydrogenase neutralizes stresses by supporting reductive glutamine metabolism and AMPK activation
  1755. The bidirectional relationship between AMPK pathway activation and myokine secretion in skeletal muscle: How it affects energy metabolism
  1756. (-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model
  1757. Structural basis of the selective activation of enzyme isoforms: Allosteric response to activators of β1-and β2-containing AMPK complexes
  1758. A single bout of exhaustive treadmill exercise increased AMPK activation associated with enhanced autophagy in mice skeletal muscle
  1759. Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells
  1760. … cells against TNF-α-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation
  1761. Lactobacillus Strains Alleviated Hyperlipidemia and Liver Steatosis in Aging Rats via Activation of AMPK
  1762. Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells
  1763. Ca2+/Calmodulin-Dependent Protein Kinase II Inhibits Hepatitis B Virus Replication from cccDNA via AMPK Activation and AKT/mTOR Suppression
  1764. Amarogentin inhibits vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia via AMPK activation
  1765. Globular adiponectin inhibits breast cancer cell growth through modulation of inflammasome activation: critical role of Sestrin2 and AMPK signaling
  1766. The Effects of NT-1044, a Novel AMPK Activator, on Endometrial Cancer Cell Proliferation, Apoptosis, Cell Stress and In Vivo Tumor Growth
  1767. Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner
  1768. Identification of novel benzimidazole derivatives as highly potent AMPK activators with anti-diabetic profiles
  1769. AMPK–mTOR–mediated activation of autophagy promotes formation of dormant polyploid giant cancer cells
  1770. ERK inhibition increases RANKL-induced osteoclast differentiation in RAW 264.7 cells by stimulating AMPK activation and RANK expression and inhibiting anti …
  1771. Dihydromyricetin protects against Doxorubicin-induced cardiotoxicity through activation of AMPK/mTOR pathway
  1772. … from the Seedlings of Various Korean Oat (Avena sativa L.) Cultivars and Screening for Adenosine 5′-Monophosphate-Activated Protein Kinase (AMPK) Activation
  1773. CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle
  1774. Adiponectin peptide alleviates oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/GSK-3β
  1775. Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus
  1776. Maternal exercise mediates hepatic metabolic programming via activation of AMPK-PGC1α axis in the offspring of obese mothers
  1777. Policosanol profiles and adenosine 5′-monophosphate-activated protein kinase (AMPK) activation potential of Korean wheat seedling extracts according to cultivar …
  1778. Targeting PP2A with lomitapide suppresses colorectal tumorigenesis through the activation of AMPK/Beclin1-mediated autophagy
  1779. Hydroxycitric Acid Inhibits Chronic Myelogenous Leukemia Growth through Activation of AMPK and mTOR Pathway
  1780. Palmatine protects against cerebral ischemia/reperfusion injury by activation of the AMPK/Nrf2 pathway
  1781. Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway
  1782. AMP-independent activator of AMPK for treatment of mitochondrial disorders
  1783. Hepatic AMPK signaling dynamic activation in response to REDOX balance are sentinel biomarkers of exercise and antioxidant intervention to improve blood glucose …
  1784. Hesperetin, a SIRT1 activator, inhibits hepatic inflammation via AMPK/CREB pathway
  1785. Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway
  1786. Nandrolone Supplementation Promotes AMPK Activation and Divergent 18[FDG] PET Brain Connectivity in Adult and Aged Mice
  1787. Natural (dihydro) phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site
  1788. Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment …
  1789. Cr (VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway
  1790. AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye
  1791. Activation of AMPK/aPKCζ/CREB pathway by metformin is associated with upregulation of GDNF and dopamine
  1792. … and Diospyros kaki Leaf Inhibits White Adipocyte Differentiation and Browning Process through AMP-Activated Protein Kinase (AMPK) Activation In Vitro and …
  1793. Celastrol exerts anti‐inflammatory effect in liver fibrosis via activation of AMPK‐SIRT3 signalling
  1794. The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway
  1795. AMPK-dependent autophagy activation and alpha-Synuclein clearance: a putative mechanism behind alpha-mangostin’s neuroprotection in a rotenone-induced …
  1796. Mitochondrial dysfunction and apoptosis are attenuated through activation of AMPK/GSK-3β/PP2A pathway in Parkinson’s disease
  1797. AMPK/p38/Nrf2 activation as a protective feedback to restrain oxidative stress and inflammation in microglia stimulated with sodium fluoride
  1798. Limonin, an AMPK activator, inhibits hepatic lipid accumulation in high fat diet fed mice
  1799. AMPK activation by AICAR reduces diet induced fatty liver in C57BL/6 mice
  1800. Inhibition of osteosarcoma cell proliferation in vitro and tumor growth in vivo in mice model by alstonine through AMPK-activation and PGC-1α/TFAM up-regulation
  1801. Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats
  1802. AMPK Activation as a Protective Mechanism to Restrain Oxidative Stress in the Insulin-Resistant State in SkeletalMuscle of Rat Model of PCOS Subjected to …
  1803. Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway
  1804. Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway in vivo and in vitro
  1805. … aggravates acute liver injury by promoting liver‐resident macrophage NLRP 3 inflammasome activation via the inhibition of AMPK/mTOR‐mediated autophagy …
  1806. Therapeutically relevant natural products as AMPK activators in the treatment of diabetes
  1807. AMPK activation is sufficient to increase skeletal muscle glucose uptake and glycogen synthesis but is not required for contraction-mediated increases in …
  1808. Gitogenin suppresses lung cancer progression by inducing apoptosis and autophagy initiation through the activation of AMPK signaling
  1809. Effects of Thiamin Restriction on Exercise-Associated Glycogen Metabolism and AMPK Activation Level in Skeletal Muscle
  1810. Antioxidants and Oxidants in Boar Spermatozoa and Their Surrounding Environment Are Associated with AMPK Activation during Liquid Storage
  1811. Metformin carbon dots for promoting periodontal bone regeneration via activation of ERK/AMPK pathway
  1812. Preclinical Development of FA5, a Novel AMP-Activated Protein Kinase (AMPK) Activator as an Innovative Drug for the Management of Bowel Inflammation
  1813. Britanin relieves ferroptosis-mediated myocardial ischaemia/reperfusion damage by upregulating GPX4 through activation of AMPK/GSK3β/Nrf2 signalling
  1814. Bupivacaine inhibits angiogenesis through oxidative stress‐dependent inhibition of Akt/mTOR and activation of AMPK
  1815. AMPK complex activation promotes sarcolemmal repair in dysferlinopathy
  1816. Ligustilide attenuates ischemic stroke injury by promoting Drp1-mediated mitochondrial fission via activation of AMPK
  1817. The Marine-Derived Macrolactone Mandelalide A Is an Indirect Activator of AMPK
  1818. … from propolis ameliorate free fatty acids-induced non-alcoholic steatohepatitis in HepG2 cells: Involvement of enhanced AMPK activation, mTOR-NF-κBp65 …
  1819. Activation of AMPK restored impaired autophagy and inhibited inflammation reaction by up-regulating SIRT1 in acute pancreatitis
  1820. GPA peptide inhibits NLRP3 inflammasome activation to ameliorate colitis through AMPK pathway
  1821. Adiponectin inhibits NLRP3 inflammasome activation in nonalcoholic steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS signaling pathways
  1822. Sustained AMPK activation and proline metabolism play critical roles in the survival of matrix-deprived transformed cells
  1823. CoenzymeQ10-induced activation of AMPK-YAP-OPA1 pathway alleviates atherosclerosis by improving mitochondrial function, inhibiting oxidative stress and …
  1824. GPR120 facilitates cholesterol efflux in macrophages through activation of AMPK signaling pathway
  1825. … Koraiensis Extract Alleviated Metabolic Syndrome Symptoms and Stimulated UCP1‐Independent Energy Consumption via AMPK Activation in White Adipose Tissue
  1826. Repeated intramuscular transplantations of hUCB-MSCs improves motor function and survival in the SOD1 G93A mice through activation of AMPK
  1827. AMPK activation suppresses mTOR/S6K1 phosphorylation and induces leucine resistance in rats with sepsis
  1828. Inhibition of VDAC1 Rescues Aβ1-42-Induced Mitochondrial Dysfunction and Ferroptosis via Activation of AMPK and Wnt/β-Catenin Pathways
  1829. AMPK activation by 5-amino-4-imidazole carboxamide riboside-1-β-D-ribofuranoside attenuates alkali injury-induced corneal fibrosis
  1830. Berbamine induced activation of the SIRT1/LKB1/AMPK signaling axis attenuates the development of hepatic steatosis in high-fat diet-induced NAFLD rats
  1831. … dysfunction by cantleyoside confines inflammatory response and promotes apoptosis of human HFLS-RA cell line via AMPK/Sirt 1/NF-κB pathway activation
  1832. Sodium acetate inhibit TGF-β1-induced activation of hepatic stellate cells by restoring AMPK or c-Jun signaling
  1833. … against hydrogen peroxide-induced oxidative damage in human retinal pigment epithelial (RPE) cells by enhancing autophagy through activation of AMPK …
  1834. Neoline Improves Memory Impairment and Reduces Amyloid-β Level and Tau Phosphorylation Through AMPK Activation in the Mouse Alzheimer’s Disease Model
  1835. Attenuation of free fatty acid (FFA)-induced skeletal muscle cell insulin resistance by resveratrol is linked to activation of AMPK and inhibition of mTOR and p70 S6K
  1836. S-petasin inhibits lipid accumulation in oleic acid-induced HepG2 cells through activation of the AMPK signaling pathway
  1837. Impact of caudal hindbrain glycogen metabolism on A2 noradrenergic neuron AMPK activation and ventromedial hypothalamic nucleus norepinephrine activity and …
  1838. Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK
  1839. Quercetin attenuates sepsis-induced acute lung injury via suppressing oxidative stress-mediated ER stress through activation of SIRT1/AMPK pathways
  1840. … differentiation of bone marrow-derived human mesenchymal stromal cells via WnT/BMP signaling and suppresses adipocyte differentiation via AMPK activation
  1841. Paeonia lactiflora root decreases lipid accumulation through the induction of lipolysis and thermogenesis via AMPK activation in 3T3‑L1 cells
  1842. GLP-1-induced AMPK activation inhibits PARP-1 and promotes LXR-mediated ABCA1 expression to protect pancreatic β-cells against cholesterol-induced …
  1843. Salsalate reverses metabolic disorders in a mouse model of non‐alcoholic fatty liver disease through AMPK activation and caspase‐6 activity inhibition
  1844. Structure activity relationships leading to the identification of the indirect activator of AMPK, R419
  1845. FNDC5 attenuates oxidative stress and NLRP3 inflammasome activation in vascular smooth muscle cells via activating the AMPK-SIRT1 signal pathway
  1846. Anti-inflammatory Role of Trilobatin on Lipopolysaccharide-induced Acute Lung Injury through Activation of AMPK/GSK3β-Nrf2 Pathway.
  1847. Inhibition of non-small cell lung cancer proliferation and survival by rosemary extract is associated with activation of ERK and AMPK
  1848. Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway
  1849. Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction
  1850. Synergetic contributions of viral VP1, VP3, and 3C to activation of the AKT-AMPK-MAPK-MTOR signaling pathway for Seneca Valley virus-induced autophagy
  1851. Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways
  1852. Neurotropin inhibits lipid accumulation by maintaining mitochondrial function in hepatocytes via AMPK activation
  1853. Soy isoflavone daidzein protects Neuro2a cells from NO stress via activation of AMPK-PGC1α pathway followed by mitochondrial enhancement
  1854. Antioxidant activity of Oenanthe stolonifera DC extract and AMPK activation on human liver cancer cells by anticancer effects
  1855. Dapagliflozin attenuates high glucose‐induced endothelial cell apoptosis and inflammation through AMPK/SIRT1 activation
  1856. Beneficial Effect of Taraxacum coreanum Nakai via the Activation of LKB1-AMPK Signaling Pathway on Obesity
  1857. Mori Ramulus suppresses hydrogen peroxide-induced oxidative damage in murine myoblast C2C12 cells through activation of AMPK
  1858. Metformin acts to suppress β-hydroxybutyric acid-mediated inflammatory responses through activation of AMPK signaling in bovine hepatocytes
  1859. Activation of melanocortin 1 receptor attenuates early brain injury in a rat model of subarachnoid hemorrhage viathe suppression of neuroinflammation …
  1860. Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway
  1861. Sulforaphane attenuates hexavalent chromium-induced cardiotoxicity via the activation of the Sesn2/AMPK/Nrf2 signaling pathway
  1862. Reactive oxygen species‐mediated oxidative stress accelerates glycolysis via activation of the CaMKKβ/AMPK pathway in the yak longissimus dorsi postmortem
  1863. Amelioration of high-insulin-induced skeletal muscle cell insulin resistance by resveratrol is linked to activation of AMPK and restoration of GLUT4 translocation
  1864. Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells
  1865. Doxorubicin cardiomyopathy is ameliorated by acacetin via Sirt1‐mediated activation of AMPK/Nrf2 signal molecules
  1866. AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation
  1867. microRNA-519d induces autophagy and apoptosis of human hepatocellular carcinoma cells through activation of the AMPK signaling pathway via Rab10
  1868. Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia–Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 …
  1869. … promotes osteogenic differentiation and antioxidant responses of mouse bone mesenchymal stem cells through activation of the AMPK/SIRT1 signaling pathway
  1870. Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
  1871. Inhalable nanoparticles/microparticles of an AMPK and Nrf2 activator for targeted pulmonary drug delivery as dry powder inhalers
  1872. Liraglutide, a glucagon-like peptide-1 receptor agonist, induces ADAM10-dependent ectodomain shedding of RAGE via AMPK activation in human aortic endothelial …
  1873. 3,4′,5-Trimethoxy-trans-stilbene Alleviates Endothelial Dysfunction in Diabetic and Obese Mice via Activation of the AMPK/SIRT1/eNOS Pathway
  1874. Concurrent Akt, ERK1/2 and AMPK activation by obestatin inhibits apoptotic signaling cascades on nutrient-deprived PC12 cells
  1875. TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation
  1876. Expression and purification of asprosin in Pichia pastoris and investigation of its increase glucose uptake activity in skeletal muscle through activation of AMPK
  1877. … in patients with anxiety and depression myocardial infarction was up-regulated and suppressed inflammation and ferroptosis by LKB1-mediated AMPK activation
  1878. Mitochondrial dysfunction regulates the JAK–STAT pathway via LKB1-mediated AMPK activation ER-stress-independent manner
  1879. Epigenetic silencing of LncRNA ANRIL enhances liver fibrosis and HSC activation through activating AMPK pathway
  1880. Fluorinated thiazolidinol drives autophagic cell death in pancreatic cancer cells via AMPK activation and perturbation of critical sentinels of oncogenic signaling
  1881. IM156, a new AMPK activator, protects against polymicrobial sepsis
  1882. Natural activators of AMPK signaling: potential role in the management of type-2 diabetes
  1883. Luteolin alleviates inorganic mercury-induced kidney injury via activation of the AMPK/mTOR autophagy pathway
  1884. Activation of AMPK suppresses S1P-induced airway smooth muscle cells proliferation and its potential mechanisms
  1885. Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
  1886. Inhibition of glycolysis ameliorate arthritis in adjuvant arthritis rats by inhibiting synoviocyte activation through AMPK/NF-кB pathway
  1887. Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway
  1888. Huayu Tongluo recipe attenuates renal oxidative stress and inflammation through the activation of AMPK/Nrf2 signaling pathway in streptozotocin-(STZ-) …
  1889. Protective effect of Jiang Tang Xiao Ke Granules against skeletal muscle IR via activation of the AMPK/SIRT1/PGC-1α signaling pathway
  1890. Functional mechanism of AMPK activation in mitochondrial regeneration of rat peritoneal macrophages mediated by uremic serum
  1891. Activation of autophagy and suppression of apoptosis by dapagliflozin attenuates experimental inflammatory bowel disease in rats: Targeting AMPK/mTOR, HMGB1 …
  1892. Activation of AMPK/miR-181b axis alleviates endothelial dysfunction and vascular inflammation in diabetic mice
  1893. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions
  1894. Hepatic proteomic changes and Sirt1/AMPK signaling activation by oxymatrine treatment in rats with non-alcoholic steatosis
  1895. Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity
  1896. Ferritinophagy is involved in Bisphenol A-induced ferroptosis of renal tubular epithelial cells through the activation of the AMPK-mTOR-ULK1 pathway
  1897. β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt …
  1898. Human prion protein-mediated calcineurin activation induces neuron cell death via AMPK and autophagy pathway
  1899. Cx32 promotes autophagy and produces resistance to SN‑induced apoptosis via activation of AMPK signalling in cervical cancer
  1900. Activation of AMPK/p38/Nrf2 is involved in resveratrol alleviating myocardial ischemia-reperfusion injury in diabetic rats as an endogenous antioxidant stress …
  1901. Neuroprotective effects of resveratrol against oxygen glucose deprivation induced mitochondrial dysfunction by activation of AMPK in SH-SY5Y cells with 3D gelatin …
  1902. Genistein accelerates glucose catabolism via activation the GPER-mediated cAMP/PKA-AMPK signaling pathway in broiler chickens
  1903. Metformin inhibits ROS production by human M2 macrophages via the activation of AMPK
  1904. Activation of autophagic flux via LKB1/AMPK/mTOR axis against xenoestrogen Bisphenol-A exposure in primary rat hepatocytes
  1905. Sulforaphane induces lipophagy through the activation of AMPK-mTOR-ULK1 pathway signaling in adipocytes
  1906. Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK–eNOS–NO pathway
  1907. Elucidating the Activation Mechanism of AMPK by Direct Pan-Activator PF-739
  1908. Indirubin-3′-oxime (IDR3O) inhibits proliferation of osteosarcoma cells in vitro and tumor growth in vivo through AMPK-activation and PGC-1α/TFAM up-regulation
  1909. Solasonine suppresses the proliferation of acute monocytic leukemia through the activation of the AMPK/FOXO3A Axis
  1910. AdipoRon, an adiponectin receptor agonist, protects contrast-induced nephropathy by suppressing oxidative stress and inflammation via activation of the AMPK …
  1911. Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity
  1912. Activation of AMPK/Sirt3 pathway by phloretin reduces mitochondrial ROS in vascular endothelium by increasing the activity of MnSOD via deacetylation
  1913. Aspiletrein A Induces Apoptosis Cell Death via Increasing Reactive Oxygen Species Generation and AMPK Activation in Non-Small-Cell Lung Cancer Cells
  1914. TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling
  1915. Penicilliumin B protects against cisplatin-induced renal tubular cell apoptosis through activation of AMPK-induced autophagy and mitochondrial biogenesis
  1916. Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
  1917. Extracellular superoxide dismutase prevents skin aging by promoting collagen production through the activation of AMPK and Nrf2/HO-1 cascades
  1918. Vanadium-protein complex inhibits human adipocyte differentiation through the activation of β-catenin and LKB1/AMPK signaling pathway
  1919. Pterostilbene inhibits FcεRI signaling through activation of the LKB1/AMPK pathway in allergic response
  1920. Beneficial and sexually dimorphic response to combined HDAC inhibitor valproate and AMPK/SIRT1 pathway activator resveratrol in the treatment of ALS …
  1921. Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation
  1922. Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates …
  1923. Ipragliflozin, an SGLT2 inhibitor, ameliorates high-fat diet-induced metabolic changes by upregulating energy expenditure through activation of the AMPK …
  1924. Calycosin-7-O-β-D-glucoside attenuates palmitate-induced lipid accumulation in hepatocytes through AMPK activation
  1925. … Attenuates Vascular Calcification in Mice with Chronic Kidney Disease by Regulating the NFR2/HO-1 Anti-Inflammatory Pathway through AMPK Activation
  1926. GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice
  1927. Intracellular Calcium Overload and Activation of CaMKK/AMPK Signaling Are Related to the Acceleration of Muscle Glycolysis of Broiler Chickens Subjected to Acute …
  1928. The activation of AMPK/NRF2 pathway in lung epithelial cells is involved in the protective effects of kinsenoside on lipopolysaccharide-induced acute lung …
  1929. Herba houttuyniae Extract Benefits Hyperlipidemic Mice via Activation of the AMPK/PGC-1α/Nrf2 Cascade
  1930. … sterol ester of α-linolenic acid improved non-alcoholic fatty liver disease by attenuating endoplasmic reticulum stress-triggered apoptosis via activation of the AMPK
  1931. … acid promotes the formation of autophagosomes in MCF-7 breast cancer cells through oxidative stress-induced growth inhibitor 1 mediated activation of AMPK/mTOR …
  1932. Activation of AdipoR1 with rCTRP9 preserves BBB integrity through the APPL1/AMPK/Nrf2 signaling pathway in ICH mice
  1933. Gryllus bimaculatus extract ameliorates high-fat diet-induced hyperglycemia and hyperlipidemia by inhibiting hepatic lipogenesis through AMPK activation
  1934. Gypenoside A protects ischemia/reperfusion injuries by suppressing miR‐143‐3p level via the activation of AMPK/Foxo1 pathway
  1935. Mogroside IIIE alleviates high glucose-induced inflammation, oxidative stress and apoptosis of podocytes by the activation of AMPK/SIRT1 signaling pathway
  1936. Activation of AMPK/mTOR-driven autophagy and inhibition of NLRP3 inflammasome by saxagliptin ameliorate ethanol-induced gastric mucosal damage
  1937. Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways
  1938. Ginkgolide B‑induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism …
  1939. … A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activation
  1940. Icariin treatment protects against gentamicin-induced ototoxicity via activation of the AMPK-SIRT3 pathway
  1941. Activation of AMPK entails the protective effect of royal jelly against high-fat-diet-induced hyperglycemia, hyperlipidemia, and non-alcoholic fatty liver disease in rats
  1942. Regulatory mechanism of fermented wheat germ on lipid metabolism in hyperlipidemia rats via activation of AMPK pathway
  1943. Baicalin promotes the activation of brown and white adipose tissue through AMPK/PGC1α pathway
  1944. AMPK‐mTOR‐ULK1 axis activation‐dependent autophagy promotes hydroxycamptothecin‐induced apoptosis in human bladder cancer cells
  1945. Activation of autophagy by sitagliptin attenuates cadmium-induced testicular impairment in rats: Targeting AMPK/mTOR and Nrf2/HO-1 pathways
  1946. Thymol alleviates LPS-induced liver inflammation and apoptosis by inhibiting NLRP3 inflammasome activation and the AMPK-mTOR-autophagy pathway
  1947. Fruits of Rosa laevigata and its bio-active principal sitostenone facilitate glucose uptake and insulin sensitivity in hepatic cells via AMPK/PPAR-γ activation
  1948. Cadmium exposure induces rat proximal tubular cells injury via p62-dependent Nrf2 nucleus translocation mediated activation of AMPK/AKT/mTOR pathway
  1949. Diet control to achieve euglycaemia induces tau hyperphosphorylation via AMPK activation in the hippocampus of diabetic rats
  1950. Resveratrol alleviates high glucose-induced oxidative stress and apoptosis in rat cardiac microvascular endothelial cell through AMPK/Sirt1 activation
  1951. Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis
  1952. Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation
  1953. Albendazole-induced autophagy blockade contributes to elevated apoptosis in cholangiocarcinoma cells through ampk/mtor activation
  1954. Curcumin represses mTORC1 signaling in Caco-2 cells by a two-sided mechanism involving the loss of IRS-1 and activation of AMPK
  1955. Anti-diabetic activity of extract from Morus nigra L. twigs through activation of AMPK/PKC pathway in mice
  1956. Cordycepin Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats via Modulation of AMPK and AKT Activation
  1957. … -induced acute kidney injury through attenuation of inflammation, oxidative stress and apoptotic effects and activation of the CaMKK–AMPK–sirt1-associated signaling …
  1958. … Protein 9 Inhibits High Glucose–Induced Oxidative Stress and Apoptosis in Retinal Pigment Epithelial Cells Through the Activation of AMPK/Nrf2 Signaling Pathway
  1959. Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
  1960. Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral …
  1961. … reveals that camel and goat milk improve glucose homeostasis in HDF/STZ-induced diabetic rats through activation of hepatic AMPK and GSK3-GYS axis
  1962. Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis
  1963. Theaflavin inhibits African swine fever virus replication by disrupting lipid metabolism through activation of the AMPK signaling pathway in virto
  1964. Methyl eugenol protects the kidney from oxidative damage in mice by blocking the Nrf2 nuclear export signal through activation of the AMPK/GSK3β axis
  1965. Taurine prevents high‐fat diet‐induced‐hepatic steatosis in rats by direct inhibition of hepatic sterol regulatory element‐binding proteins and activation of AMPK
  1966. Ym155 localizes to the mitochondria leading to mitochondria dysfunction and activation of AMPK that inhibits BMP signaling in lung cancer cells
  1967. Sinensol-C Isolated from Spiranthes sinensis Inhibits Adipogenesis in 3T3-L1 Cells through the Regulation of Adipogenic Transcription Factors and AMPK Activation
  1968. … glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK/FoxO1/AKT/GSK3β …
  1969. Activation of AMPK sensitizes medulloblastoma to Vismodegib and overcomes Vismodegib‐resistance
  1970. Targeted Activation of HNF4α by AMPK Inhibits Apoptosis and Ameliorates Neurological Injury Caused by Cardiac Arrest in Rats
  1971. Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway
  1972. Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue
  1973. Evaluation of AMPK activity in mice by measuring activator-induced glucose uptake
  1974. AMPK activation increases postoperative cognitive impairment in intermittent hypoxia rats via direct activating PAK2
  1975. … of Portulaca Oleracea L., HM-chromanone, improves palmitate-induced insulin resistance by inhibiting mTOR/S6K1 through activation of the AMPK pathway in L6 …
  1976. Vitexin attenuates autoimmune hepatitis in mouse induced by syngeneic liver cytosolic proteins via activation of AMPK/AKT/GSK-3β/Nrf2 pathway
  1977. Protein kinase CK2 activates Nrf2 via autophagic degradation of Keap1 and activation of AMPK in human cancer cells
  1978. Renal denervation improves vascular endothelial dysfunction by inducing autophagy via AMPK/mTOR signaling activation in a rat model of type 2 diabetes mellitus …
  1979. Inhibiting lysosomal aldolase: a magic bullet for AMPK activation in treating metabolic disease?
  1980. mTORC1 silencing during intestinal epithelial Caco-2 cell differentiation is mediated by the activation of the AMPK/TSC2 pathway
  1981. … seed polyphenol protects the blood–brain barrier through inhibiting Aβ (25–35)‐induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1‐mediated …
  1982. … ischemia/reperfusion injury-induced cardiomyocytes apoptosis by alleviating endoplasmic reticulum stress via activation of AMPK-PAK2 signaling in H9C2 …
  1983. … sensitivity and mitochondrial respiration in skeletal muscle of type-2 diabetic mice through insulin signaling pathway and AMPK/SIRT1/PGC-1α/PPAR-γ activation
  1984. AMPK promotes Arf6 activation in a kinase-independent manner upon glucose starvation
  1985. Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function
  1986. Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs–EBP interaction recover NAFLD through enhancing mitochondrial function in mice
  1987. The AMPK pathway triggers autophagy during CSF1-induced microglial activation and may be implicated in inducing neuropathic pain
  1988. Secretory clusterin promotes oral cancer cell survival via inhibiting apoptosis by activation of autophagy in AMPK/mTOR/ULK1 dependent pathway
  1989. Activation of AMPK by telmisartan decreases basal and PDGF-stimulated VSMC proliferation via inhibiting the mTOR/p70S6K signaling axis
  1990. Biochanin A induces a brown‐fat phenotype via improvement of mitochondrial biogenesis and activation of AMPK signaling in murine C3H10T1/2 mesenchymal stem …
  1991. Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function
  1992. Triiodothyronine potentiates BMP9-induced osteogenesis in mesenchymal stem cells through the activation of AMPK/p38 signaling
  1993. … , 2-phenyl-1, 4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators
  1994. Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice
  1995. Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis
  1996. VRK-1 extends life span by activation of AMPK via phosphorylation
  1997. Imidazo[1,2‐a]pyridine Derivatives as AMPK Activators: Synthesis, Structure–Activity Relationships, and Regulation of Reactive Oxygen Species in Renal Fibroblasts
  1998. … neointimal hyperplasia and prevents vascular smooth muscle cell dedifferentiation, proliferation, and migration via activation of AMPK/PPAR-γ signaling
  1999. … aggravation and lung injury by modulating AMPK/PI3K/Akt/p38-NF-κB and TGF-β/Smad/Bcl2/caspase/LC3 cascade and macrophages activation in murine model of …
  2000. Atractyloside Protect Mice Against Liver Steatosis by Activation of Autophagy via ANT-AMPK-mTORC1 Signaling Pathway
  2001. … protects human skin keratinocytes against ultraviolet B-induced photodamage via autophagy activation by regulating the AMPK-mTOR signaling pathway
  2002. Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α …
  2003. The protective effects of corn oligopeptides on acute alcoholic liver disease by inhibiting the activation of kupffer cells NF-κB/AMPK signal pathway
  2004. … Spared Nerve Injury-Induced Neuropathic Pain in Mice by Inhibiting Microglia Activation and Neuronal Oxidative Damage in the Spinal Cord via the AMPK Pathway
  2005. Naringin promotes fat browning mediated by UCP1 activation via the AMPK signaling pathway in 3T3-L1 adipocytes
  2006. RETRACTED ARTICLE: MicroRNA-206 inhibition and activation of the AMPK/Nampt signalling pathway enhance sevoflurane post-conditioning-induced amelioration …
  2007. Mogroside V alleviates lipopolysaccharide-induced neuroinflammation via inhibition of TLR4-MyD88 and activation of AKT/AMPK-Nrf2 signaling pathway
  2008. Activation of AMPK‐dependent autophagy in the nucleus accumbens opposes cocaine‐induced behaviors of mice
  2009. … effect of sulforaphane against oxidative stress in granulosa cells of patients with polycystic ovary syndrome (PCOS) through activation of AMPK/AKT/NRF2 signaling …
  2010. Exercise improves homeostasis of the intestinal epithelium by activation of APJ‐AMPK signaling
  2011. Soyasapogenol C from Fermented Soybean (Glycine Max) Acting as a Novel AMPK/PPARα Dual Activator Ameliorates Hepatic Steatosis: A Novel SANDA …
  2012. TRPV1 activation mitigates hypoxic injury in mouse cardiomyocytes by inducing autophagy through the AMPK signaling pathway
  2013. Prostaglandin EP3 receptor activation is antinociceptive in sensory neurons via PI3Kγ, AMPK and GRK2
  2014. Chrysanthemum morifolium Flower Extract Inhibits Adipogenesis of 3T3-L1 Cells via AMPK/SIRT1 Pathway Activation
  2015. Aerobic exercise ameliorates myocardial ischemia/reperfusion injury and thrombosis of diabetic rats via activation of AMPK/Sirt1/PGC-1α pathway.
  2016. Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function
  2017. Dehydroepiandrosterone protects against hepatic glycolipid metabolic disorder and insulin resistance induced by high fat via activation of AMPK-PGC-1α-NRF-1 and …
  2018. Comprehensive Comparisons between Grafted Kynam Agarwood and Normal Agarwood on Traits, Composition, and In Vitro Activation of AMPK
  2019. n-Butylidenephthalide inhibits the phenotypic switch of VSMCs through activation of AMPK and prevents stenosis in an arteriovenous fistula rat model
  2020. Effect of curcumin on IL-17A mediated pulmonary AMPK kinase/cyclooxygenase-2 expressions via activation of NFκB in bleomycin-induced acute lung injury in vivo
  2021. Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway
  2022. Teaghrelin Protects SH-SY5Y Cells against MPP+-Induced Neurotoxicity through Activation of AMPK/SIRT1/PGC-1α and ERK1/2 Pathways
  2023. Dexmedetomidine protects against septic liver injury by enhancing autophagy through activation of the AMPK/SIRT1 signaling pathway
  2024. Activation of AMPK inhibits Galectin-3-induced pulmonary artery smooth muscle cells proliferation by upregulating hippo signaling effector YAP
  2025. Inhibition Effect of Adipogenesis and Lipogenesis via Activation of AMPK in Preadipocytes Treated with Canavalia gladiata Extract
  2026. Apelin-13 protects dopaminergic neurons against rotenone—induced neurotoxicity through the AMPK/mTOR/ULK-1 mediated autophagy activation
  2027. Lactobacillus plantarum postbiotics trigger AMPK‐dependent autophagy to suppress Salmonella intracellular infection and NLRP3 inflammasome activation
  2028. Kiss1 Inhibits the Proliferation of Nasopharyngeal Carcinoma Cells Via Activation of the LKB1/AMPK Pathway
  2029. (−)-Hydroxycitric acid regulates energy metabolism by activation of AMPK-PGC1α-NRF1 signal pathway in primary chicken hepatocytes
  2030. Hepatic AMPK signaling activation in response to dynamic REDOX balance is a biomarker of exercise to improve blood glucose control.
  2031. Vitamin D3 potentiates the nephroprotective effects of metformin in a rat model of metabolic syndrome: Role of AMPK/SIRT1 activation and DPP-4 inhibition
  2032. … ) Inhibits Proliferation, Suppresses Cell Migration and Invasion and Decreases Tumor Growth of Osteosarcoma: Role of PGC-1α/TFAM and AMPK-Activation
  2033. … cadmium chloride-induced memory loss and hippocampal apoptosis by increased intracellular glutathione stores and activation of PTEN/AMPK induced inhibition of …
  2034. Ampk activation by glycogen expenditure primes the exit of naive pluripotency
  2035. Coix lacryma-jobi seed oil reduces fat accumulation in nonalcoholic fatty liver disease by inhibiting the activation of the p-AMPK/SePP1/ApoER2 pathway
  2036. Wheat bran oil concentrate induced AMPK activation, insulin and lipid homeostasis alleviates adipokines and cytokine in high fat fed C57BL6 mice
  2037. … protects against oleic acid-triggered mitochondrial dysfunction to relieve oxidative stress and inflammation via activation of the AMPK-Nrf2 axis by targeting GPR30 in …
  2038. Irisin Regulates Hepatic Glucose Metabolism via AMPK and PI3K/Akt Activation
  2039. UBE3A deficiency-induced autophagy is associated with activation of AMPK-ULK1 and p53 pathways
  2040. CD73 aggravates alcohol-related liver fibrosis by promoting autophagy mediated activation of hepatic stellate cells through AMPK/AKT/mTOR signaling …
  2041. Activation of AMPK/proteasome/MLCK degradation signaling axis by telmisartan inhibits VSMC contractility and vessel contraction
  2042. Neoagarotetraose extends the lifespan of Caenorhabditis elegans through AMPK mediated signaling pathways and activation of autophagy
  2043. Prior AICAR induces elevated glucose uptake concomitant with greater γ3-AMPK activation and reduced membrane cholesterol in skeletal muscle from 26-month-old …
  2044. Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway
  2045. Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling
  2046. Activation of AMPK signalling by Metformin: Implication an important molecular mechanism for protecting against mice silicosis via inhibited endothelial cell-to …
  2047. Lipid Extract From a Vegetable (Sonchus Oleraceus) Attenuates Adipogenesis and High Fat Diet-Induced Obesity Associated With AMPK Activation
  2048. Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO2-induced liver injury under oxidative stress
  2049. AMPK Activation Enhances Neutrophil’s Fungicidal Activity in Vitro and Improves the Clinical Outcome of Fusarium solani Keratitis in Vivo
  2050. Ameliorative Effects of Lactobacillus plantarum HAC01 Lysate on 3T3-L1 Adipocyte Differentiation via AMPK Activation and MAPK Inhibition
  2051. Pre-extinction activation of hippocampal AMPK prevents fear renewal in mice
  2052. Xuezhikang alleviates lipid accumulation via AMPK activation in hepatocellular steatosis model
  2053. Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation
  2054. Seabuckthorn Reverses High-Fat-Diet-Induced Obesity and Enhances Fat Browning via Activation of AMPK/SIRT1 Pathway
  2055. Exendin-4 increases scavenger receptor class BI expression via activation of AMPK/FoxO1 in human vascular endothelial cells
  2056. Blueberry Stem Extract Prevents Lacrimal Hyposecretion in Non-obese Diabetic Mice via Activation of AMPK
  2057. The AMPK activator A-769662 inhibits human TASK3 potassium channels in an AMPK-independent manner
  2058. Walnut-Derived Peptides Promote Autophagy via the Activation of AMPK/mTOR/ULK1 Pathway to Ameliorate Hyperglycemia in Type 2 Diabetic Mice
  2059. A long-term high-fat diet influences brain damage and is linked to the activation of HIF-1α/AMPK/mTOR/p70S6K signalling
  2060. Combination of mTOR inhibitor PP242 and AMPK activator metformin exerts enhanced inhibitory effects on colorectal carcinoma cells in vitro by blocking multiple …
  2061. … contractility modulation ameliorates myocardial metabolic remodeling in a rabbit model of chronic heart failure through activation of AMPK and PPAR-α …
  2062. The natural compound rutaecarpine promotes white adipocyte browning through activation of the AMPK-PRDM16 axis
  2063. … alleviated doxorubicin induced JNK activation and Cx43 phosphorylation associated cardiotoxicity via activation of AMPK-SHP2 signaling pathway
  2064. Validation of the antidiabetic potential of isolated and nanoemulsified endophytic fungal metabolite 2, 4, 6-triphenylaniline through AMPK activation pathway
  2065. … improves mitochondrial function in oxygen-glucose deprivation and reperfusion-induced cardiomyocyte injury by activation of the AMPK/PGC-1 axis
  2066. Canagliflozin facilitates reverse cholesterol transport through activation of AMPK/ABC transporter pathway
  2067. Role of exercise on alleviating pressure overload-induced left ventricular dysfunction and remodeling via AMPK-dependent autophagy activation
  2068. Prospective evaluation of effect of metformin on activation of amp-activated protein kinase (ampk) and disease control in a sub-group analysis of patients with …
  2069. Hepatic AMPK activation in response to dynamic REDOX balance is a biomarker of exercise to improve blood glucose control
  2070. Salidroside promotes osteoblast proliferation and differentiation via the activation of AMPK to inhibit bone resorption of knee osteoarthritis mice
  2071. Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway
  2072. Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway
  2073. Activation of Ca2+‐AMPK‐mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts
  2074. … tanshinone IIA silate alleviates high glucose induced barrier impairment of human retinal pigment epithelium through the reduction of NF-κB activation via the AMPK …
  2075. The activation of Wnt signaling facilitates autophagy by modulating GSK-3β-AMPK axis in atherosclerosis
  2076. Loliolide from Artemisia princeps Suppresses Adipogenesis in Human Bone Marrow-Derived Mesenchymal Stromal Cells via Activation of AMPK and Wnt/β-catenin …
  2077. Crataegus aronia prevents high‐fat diet‐induced hepatic steatosis in rats by activating AMPK‐induced suppression of SREBP1 and activation of PPARα
  2078. FFAR2 antagonizes TLR2-and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB
  2079. AMPK mediates early activation of the unfolded protein response through a positive feedback loop in palmitate-treated muscle cells
  2080. Magnolol improves Alzheimer’s disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway
  2081. Apocarotenoids from Equisetum debile Roxb. ex Vaucher regulate the lipid metabolism via the activation of the AMPK/ACC/SREBP-1c signaling pathway
  2082. Calycosin alleviates injury in airway epithelial cells caused by PM 2.5 exposure via activation of AMPK signalling
  2083. Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor
  2084. … partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation
  2085. … -3-O-rutinoside from Moringa oleifera Downregulates Adipogenesis and Lipid Accumulation and Improves Glucose Uptake by Activation of AMPK/Glut-4 in …
  2086. 6-Phosphogluconate dehydrogenase inhibition arrests growth and induces apoptosis in gastric cancer via AMPK activation and oxidative stress
  2087. Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK …
  2088. Targeting Breast Cancer and Their Stem Cell Population through AMPK Activation: Novel Insights. Cells 2022, 11, 576
  2089. Integrated single-cell RNA-seq analysis revealed podocyte injury through activation of the BMP7/AMPK/mTOR mediated autophagy pathway
  2090. Blockage of fibronectin 1 ameliorates myocardial ischemia/reperfusion injury in association with activation of AMP-LKB1-AMPK signaling pathway
  2091. Fructus Zanthoxyli extract improves glycolipid metabolism disorder of type 2 diabetes mellitus via activation of AMPK/PI3K/Akt pathway: Network pharmacology and …
  2092. Osteosarcoma Cell Growth Inhibition by Isoxanthanol-Nanoparticles through Histone H3 Lysine 27 Trimethylation Downregulation and AMPK Activation
  2093. PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis
  2094. AMPK Activation Improves Recovery from Pneumonia-Induced Lung Injury via Reduction of ER-Stress and Apoptosis in Alveolar Epithelial Cells
  2095. … Mellitus by Activating Monophosphate-Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Axis and Inhibiting Nuclear Factor-kappa B (NF-κB) Activation
  2096. … factor‐related protein 9 protects cultured chondrocytes from IL‐1β‐induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK …
  2097. Dehydroepiandrosterone alleviates oleic acid-induced lipid metabolism disorders through activation of AMPK-mTOR signal pathway in primary chicken …
  2098. Florofangchinoline inhibits proliferation of osteosarcoma cells via targeting of histone H3 lysine 27 trimethylation and AMPK activation
  2099. Increased effects of 2, 5-dimethylcelecoxib on sensitivity of hepatocellular carcinoma cells to sorafenib via CYP3A5 expression and activation of AMPK
  2100. Identification of flavone C-glycosides from Glycyrrhiza uralensis seeds and their effects on AMPK activation
  2101. Cytosolic 5′-nucleotidase II silencing in lung tumor cells regulates metabolism through activation of the p53/AMPK signaling pathway
  2102. Effects of short-term fasting and pharmacological activation of AMPK on metabolism of rat adipocytes
  2103. EGR‑1 plays a protective role in AMPK inhibitor compound C‑induced apoptosis through ROS‑induced ERK activation in skin cancer cells
  2104. Alcohol Aggravates Acute Pancreatitis by Impairing Autophagic Flux Through Activation of AMPK Signaling Pathway
  2105. Purple corn extract (PCE) alleviates cigarette smoke (CS)-induced DNA damage in rodent blood cells by activation of AMPK/Foxo3a/MnSOD pathway
  2106. β-Boswellic Acid Suppresses Breast Precancerous Lesions via GLUT1 Targeting-Mediated Glycolysis Inhibition and AMPK Pathway Activation
  2107. Activation of the AMPK-ULK1 pathway mediated protective autophagy by sevoflurane anesthesia restrains LPS-induced acute lung injury (ALI)
  2108. Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
  2109. Enhanced Oxygen Utilization Efficiency With Concomitant Activation of AMPK-TBC1D1 Signaling Nexus in Cyclophilin-D Conditional Knockout Mice
  2110. RETRACTED: Zhou et al. Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-Catenin Downregulation and AMPK Activation. Pharmaceutics 2021, 13 …
  2111. Highlighting the Protective or Degenerative Role of AMPK Activators in Dementia Experimental Models
  2112. Vascular Biology and Microcirculation: AMPK activation in pregnant human myometrial arteries from high-altitude and intrauterine growth-restricted …
  2113. Novel Dual mTOR Inhibitor/AMPK Activator Mitigates Doxorubicin Cardiotoxicity and Potentiates Its Chemotherapeutic Efficacy Against Triple Negative Breast Cancer
  2114. Abnormal in LMNA triggers a shift in intracellular metabolic homeostasis via AMPK activation
  2115. Activation of AMPK pathway compromises Rab11 downregulation-mediated inhibition of Schwann cell proliferation in a Glut1 and Glut3-dependent manner
  2116. The Role of AMPK Signaling in Brown Adipose Tissue Activation. Cells 2021, 10, 1122
  2117. Cordycepin inhibits the proliferation and migration of human gastric cancer cells by suppressing lipid metabolism via AMPK and MAPK activation
  2118. … inhibits VEGF-induced HUVECs proliferation, migration and invasion through AMPK/mTOR pathway-dependent autophagy activation and cell cycle arrest
  2119. … cell-derived factor-1 (SDF-1) suppresses the NLRP3 inflammasome and inhibits pyroptosis in synoviocytes from osteoarthritic joints via activation of the AMPK …
  2120. Exendin-4 protects against myocardial ischemia-reperfusion injury by upregulation of SIRT1 and SIRT3 and activation of AMPK
  2121. Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway
  2122. … protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway
  2123. … –Arginine–Tryptophan) Improves Glucose Tolerance in High Fat Diet Fed C57BL/6 Mice via Activation of Insulin Signaling and AMPK Pathways in Skeletal …
  2124. ZG02 Improved hepatic glucose metabolism and insulin sensitivity via activation of AMPK/Sirt1 signaling pathways in a high-fat diet/streptozotocin-induced Type 2 …
  2125. Energy Provisioning and Inflammasome Activation: The Pivotal Role of AMPK in Sterile Inflammation and Associated Metabolic Disorders
  2126. AMPK Activator Metformin Alters Oligodendrocyte Energetics to Promote Cellular Differentiation and Accelerate Remyelination in the Cuprizone Model of Myelin …
  2127. Cyanidin-3-O-glucoside attenuates high glucose–induced podocyte dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK …
  2128. Carnosic acid attenuates inflammation, oxidative stress and mitochondrial dysfunction in neurons via activation of AMPK/SIRT1 pathway
  2129. Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex
  2130. I15 Reduction of glutamate dehydrogenase induces autophagy via tor inhibition and AMPK activation in a drosophila model for Huntington’s disease
  2131. Restriction of intracellular Salmonella typhimurium growth by the small-molecule autophagy inducer A77 1726 through the activation of the AMPK-ULK1 axis
  2132. Dietary Activation of AMP-Activated Protein Kinase (AMPK) to Treat Insulin Resistance
  2133. Antihyperalgesia effect of AMP-activated protein kinase (AMPK) activators in a mouse model of postoperative pain
  2134. Role for toll-like receptor 9 in muscle AMPK activation
  2135. … lipopolysaccharide‑induced BEAS‑2B cell injury through inhibition of endoplasmic reticulum stress via activation of the AMPK/SIRT1 signaling pathway
  2136. Natural Phenolic Compounds Targeting The AMPK Activation For Metabolic Health
  2137. Bariatric surgery improves autophagy and leukocyte-endothelial cell interactions through AMPK activation at one year follow-up
  2138. OR2H2 Activation Suppresses Cellular Senescence and Aging by Activating AMPK and Inducing Senolysis in VK2/E6E7 Cells
  2139. Dexmedetomidine associated lung cancer proliferation and tumor growth is prevented by β-caryophyllene: Role of AMPK activation and PGC-1α/TFAM over …
  2140. Metformin Inhibits STAT3 and MAPK Signaling through AMPK Activation in CSF3RT618I Cells
  2141. The Effects of NT-1044, a Novel AMPK Activator, on Endometrial Cancer Cell Proliferation, Apoptosis, Cell Stress and In Vivo Tumor Growth
  2142. Oxyresveratrol and its synthetic derivatives on the stimulation of glucose uptake in skeletal muscle cells and the activation of AMPK.
  2143. Small-molecule 7, 8-dihydroxyflavone counteracts compensated and decompensated cardiac hypertrophy via AMPK activation
  2144. Salidroside inhibits insulin resistance and hepatic steatosis by downregulating miR-21 and subsequent activation of AMPK and upregulation of PPARα in the liver and …
  2145. Compound 13 Promotes Epidermal Healing in Mouse Fetuses via Activation of AMPK
  2146. Treatment Of Human Pulmonary Microvascular Endothelial Cells with NO leads to Increased PDE3A Protein Expression and AMPK Activation
  2147. Chlorogenic acid modulates glucose and lipid metabolisms via AMPK activation in HepG2 cells and shows its anti-hyperglycemic effect on streptozocin-induced …
  2148. … : Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling …
  2149. … Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation
  2150. AMPK activation protects against prostate cancer by inducing a catabolic cellular state
  2151. Anti-diabetic effects of glucomanno-oligosaccharides via AMPK activation in C2C12 myotubes
  2152. Linagliptin improves high glucose-induced glomerular endothelial hyper-permeability through AMPK activation and RhoA/ROCK suppression
  2153. … 1 blocker candesartan improves morphine tolerance by reducing morphine‑induced inflammatory response and cellular activation of BV2 cells via the PPARγ/AMPK …
  2154. Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-catenin Downregulation and AMPK Activation. Pharmaceutics 2021, 13, 330
  2155. XAF1 directs glioma response to temozolomide through apoptotic transition of autophagy by activation of ATM–AMPK signaling
  2156. [6]-Gingerol Suppresses Oral Cancer Cell Growth by Inducing the Activation of AMPK and Suppressing the AKT/mTOR Signaling Pathway
  2157. MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis Corrigendum in/10.3892/etm. 2022.11390
  2158. Myeloid deletion and therapeutic activation of AMP-activated protein kinase (AMPK) do not alter atherosclerosis in male or female mice
  2159. Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs
  2160. Protective effects of a new AMPK activator, LNP599, in a marmoset model of diet-induced obesity and dyslipidemia
  2161. New Insights into the Activation Mechanisms of AMPK
  2162. Discovery of 3, 5-Dimethylpyridin-4 (1H)-one Derivatives as Activators of AMP-Activated Protein Kinase (AMPK)
  2163. Energy deprivation-induced AMPK activation inhibits milk synthesis via PrlR and PGC-1α
  2164. PFKFB2 inhibits ferroptosis in myocardial ischemia/reperfusion injury through AMPK activation.
  2165. Cinnamtannin D1 ameliorates DSS-induced colitis by preventing Th17/Treg imbalance through activation of the AMPK/mTOR pathway
  2166. 588-P: Probing the Role of Muscle Glycogen Resynthesis on Postexercise AMPK Activation and Metabolic Protein Abundance Using a Novel Genetic Model
  2167. Inhibition of osteosarcoma cell proliferation by matrine (MT) via targeting histone H3 lysine 27 trimethylation and AMPK activation
  2168. Betulinic Acid Stimulates Glucose Uptake through the Activation of PI3K and AMPK in 3T3-L1 Adipocytes
  2169. 1507-P: Carnosic Acid–Induced Browning in 3T3-L1 Adipocytes Is Dependent on AMPK Activation
  2170. Maintenance of AMPK activation by metformin is beneficial for suppressing the progress of diabetes-accelerated atherosclerosis via inhibition of vascular smooth …
  2171. The janus face of vascular AMPK activation
  2172. AMPK Activation Protects Against Pulmonary Hypertension in Rats and Relaxes Isolated Human Pulmonary Artery
  2173. … -4-One Isolated from Artemisia princeps Suppresses Adipogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stromal Cells via Activation of AMPK
  2174. 266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles
  2175. Chronic AMPK activation reduces synaptic plasticity markers in Neuronal SH‐SY5Y Cells
  2176. … Li, Benoit Viollet, Ming-Hui Zou, and Zhonglin Xie. AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1 …
  2177. Validation of direct AMP kinase (AMPK) activation for treatment of X-linked Adrenoleukodystrophy
  2178. Withdrawal: Activation of autophagic flux against xenoestrogen bisphenol-A-Induced hippocampal neurodegeneration via AMP kinase (AMPK)/mammalian target of …
  2179. MO019: Preclinical Efficacy of Direct AMPK Activation with a Novel Small Molecule–PXL770–For the Treatment of Autosomal Dominant Polycystic Kidney Disease
  2180. Dual Ampk Activator/mtor Inhibitor Improves Metabolic Parameters in T2d Mice and Protects Cardiomyocytes Against Ischemic Injury
  2181. Oestrogen Receptors ERα, ERβ and GPER Mediate the Activation of AMPK and the Inhibition of the Inflammatory Signaling Pathway TLR4/NFκB in Neutrophils …
  2182. POS-410 THE IMPORTANT FUNCTION OF ADORA2B-MEDIATED AMPK ACTIVATION IN ERYTHROCYTES IN CHRONIC KIDNEY DISEASE
  2183. AMPK Regulates Untimely Transcriptional Activation and R-loop Formation to Protect Genome Stability
  2184. Activation of AMPK Ameliorates Acute Severe Pancreatitis by Suppressing Pancreatic Acinar Cell Necroptosis in Obese Mice Models
  2185. deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway
  2186. Physcion alleviates chronic alcoholic hepatic inflammation and pyroptosis through SIRT1-AMPK activation
  2187. POS-382 A New AMPK Activator PA-S14 Attenuates Renal Injury through Promoting Autophagy
  2188. 4.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway
  2189. AMPK activation alleviates stroke severity in mice with chronic kidney disease
  2190. Study on the relationship between relieving energy crisis in myofascial trigger points with An-Pressing manipulation and AMPK/PGC-1α pathway activation
  2191. AMPK Activation, A Target of Metformin, is Associated with the Risk of Psoriasis and its Comorbidities in the UK Biobank: A Mendelian Randomization Study
  2192. AMPK activator alleviates pancreatic injury in rat models with severe acute pancreatitis
  2193. Chronic Transient Hypoxia Alleviates High Fat Diet-Induced Obesity and Fatty Liver in C57 Mice by Upregulating Epinephrine Levels and Activation of AMPK
  2194. 5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation
  2195. Tie2-mediated AMPK activation by ferritin-based protein C nanoparticles inhibits advanced prostate cancer development through induction of vasodilation
  2196. NLRP3 inflammasome activation attenuates neuronal apoptosis by upregulating autophagy through AMPK/Beclin-1 pathway after intracerebral hemorrhage with …
  2197. Novel Duel Mtor Inhibitors/AMPK Activators Improve Therapeutic Efficacy of Doxorubicin and Ameliorate Its Associated Cardiotoxicity in Mice
  2198. Atrial Remodeling is Attenuated by Dual Cannabinoid Receptor Agonist Via AMPK Activation and AERP Reduction
  2199. 1820-P: A Direct AMPK Activator Reduces Liver Steatosis in a Mouse Model of NASH
  2200. … sensing hypothalamic GT1-7 neuronal cells and pancreatic αTC1. 9 α-cells to examine the effect of R481 on AMPK pathway activation and cellular metabolism …
  2201. Facilitation of Glucose Uptake by Lupeol through the Activation of the PI3K/AKT and AMPK Dependent Pathways in 3T3-L1 Adipocytes
  2202. AMPK activation by 5-Amino-4-Imidazole Carboxamide Riboside-1-β-D-Ribofuranoside attenuates alkali Injury-Induced corneal fibrosis
  2203. The anti‐tumourigenic effect of ellagic acid in SKOV‐3 ovarian cancer cells entails activation of autophagy mediated by inhibiting Akt and activating AMPK
  2204. Overexpression of microRNA-9 inhibits 3T3-L1 cell adipogenesis by targeting PNPLA3 via activation of AMPK
  2205. MAP4K3 inhibits Sirtuin-1 to repress the LKB1–AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex
  2206. … BY PROMOTING LIVER-RESIDENT MACROPHAGE NLRP3 INFLAMMASOME ACTIVATION VIA THE INHIBITION OF AMPK/MTOR-MEDIATED AUTOPHAGY …
  2207. White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function
  2208. Pharmacological activation of AMPK prevents aircraft noise induced oxidative stress, endothelial dysfunction and vascular inflammation
  2209. Author correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK-and PTP1B-dependent processes
  2210. ACTIVATOR vs INHIBITOR OF β-ISOFORMS OF AMPK: TOWARDS THE UNDERSTANDING OF ENZYMATIC MECHANISM
  2211. Ginsenoside Rg3 modulates glucose metabolism and ameliorates myocardial insulin resistance through activation of AMPK pathway in TAC-induced heart failure
  2212. Anti-myeloma Effects of Xanthohumol on Human Multiple Myeloma Cells in Vitro via Induction of Apoptosis and Activation of AMPK Pathway
  2213. GLP-1R Activation Ameliorate Novel-object Recognition Function via Hippocampal AMPK/NF-κB Signaling Pathway in Neuropathic Pain Mice
  2214. Metformin protects RPE cells from oxidative damage by enhancing autophagy through activation of AMPK pathway
  2215. Colon Cancer Cell Death by Synergistic Activity of Phytochemicals is Modulated by Increased ROS, Activation of AMPK, and Inhibition of mTORC1
  2216. Artemisinin protected human bronchial epithelial cells from amiodarone-induced oxidative damage via activation of 5’AMP-activated protein kinase (AMPK)
  2217. … to” Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway”[Biomed …
  2218. AMPK/mTOR Pathway Mediates Autophagy Activation in Colistin-Induced Nephrotoxicity
  2219. Corrigendum to’Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions'[Brain …
  2220. Type-2-diabetes: Regulation of AMPK pathway using Natural and Synthetic Activators: A Systematic Review
  2221. The protective effect of artemisinin against hydrogen peroxide-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK
  2222. Protective effect of metformin against hydrogen peroxide induced oxidative damage in RPE cells by enhancing autophagy through activation of AMPK pathway …
  2223. Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis
  2224. Artemisinin prevented D407 cells from amiodarone-induced oxidative damage via activation of CaMKK2/AMPK/Nrf2 signaling pathway
  2225. … inhibition of mitochondrial soluble adenylyl cyclase (sAC) in astrocytes causes activation of AMP-activated protein kinase (AMPK) and induces breakdown of …
  2226. Artemisinin protected human retinal pigment epithelial cells from amiodarone-induced oxidative damage via activation of CaMKK2/AMPK/Nrf2 signaling pathway
  2227. Protective effect of Artemisinin against Hydrogen Peroxide (H2O2)-Induced Oxidative Damage in SH-SY5Y and Hippocampal Neurons through Activation of AMPK …
  2228. Vitamin D3 potentiates the nephroprotective effects of metformin in a rat model of metabolic syndrome: Role of AMPK/SIRT1 activation and DPP-4 inhibition
  2229. AMPK/SIRT1/PGC-1α/SIRT3 pathway-independent activation of GPx1 expression by metformin in the heart of a mouse model of endometriosis
  2230. The beneficial effect of Coix lacryma-jobi var. ma-yuen (Roman.) Stapf sprout the activation of LKB1/AMPK/SIRT1 signaling pathway on obesity
  2231. [Corrigendum] MicroRNA‑506‑3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis
  2232. … -Derived Factor-1 (SDF-1) Suppresses the NLRP3 In ammasome and Inhibits Pyroptosis in Synoviocytes from Osteoarthritic Joints via Activation of the AMPK …
  2233. Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease
  2234. AMPK activation by A-769662 controls IL-6 expression in inflammatory arthritis
  2235. Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
  2236. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation
  2237. Gallic acid regulates body weight and glucose homeostasis through AMPK activation
  2238. Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
  2239. AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors
  2240. AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARα and PGC-1
  2241. A potent and selective AMPK activator that inhibits de novo lipogenesis
  2242. Adiponectin represses colon cancer cell proliferation via AdipoR1-and-R2-mediated AMPK activation
  2243. AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass
  2244. Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression
  2245. AMPK activates autophagy by phosphorylating ULK1
  2246. Anti-adipogenic effect of dioxinodehydroeckol via AMPK activation in 3T3-L1 adipocytes
  2247. Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model
  2248. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
  2249. Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury
  2250. Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation
  2251. Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury
  2252. Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
  2253. IRE1-dependent activation of AMPK in response to nitric oxide
  2254. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity
  2255. Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells
  2256. Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A (y) mice
  2257. Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders
  2258. TAK1 activates AMPK‐dependent cytoprotective autophagy in TRAIL‐treated epithelial cells
  2259. Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats
  2260. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
  2261. Fructose-induced hypothalamic AMPK activation stimulates hepatic PEPCK and gluconeogenesis due to increased corticosterone levels
  2262. Resveratrol induces cell apoptosis in adipocytes via AMPK activation
  2263. Selected compounds derived from Moutan Cortex stimulated glucose uptake and glycogen synthesis via AMPK activation in human HepG2 cells
  2264. AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells
  2265. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
  2266. Indazole-Type Alkaloids from Nigella sativa Seeds Exhibit Antihyperglycemic Effects via AMPK Activation in Vitro
  2267. The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells
  2268. Electroacupuncture improves cognitive deficits associated with AMPK activation in SAMP8 mice
  2269. AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells
  2270. AMPK activation affects glutamate metabolism in astrocytes
  2271. AMP-Activated Protein Kinase (AMPK) Activation by Benzofurans and Coumestans Isolated from Erythrina abyssinica
  2272. Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism
  2273. … improves the mechanical performance of the post-infarcted diabetic myocardium: a response associated with up-regulation of Akt/mTOR and AMPK activation
  2274. … associated with survival outcomes of colorectal cancer cell but AMPK activator AICAR sensitizes anticancer effect of 5-fluorouracil through AMPK activation
  2275. Inability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbance
  2276. Pomegranate vinegar beverage reduces visceral fat accumulation in association with AMPK activation in overweight women: A double-blind, randomized, and …
  2277. Hispidulin sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by AMPK activation leading to Mcl-1 block in translation
  2278. Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP
  2279. Acute exercise activates AMPK and eNOS in the mouse aorta
  2280. Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas
  2281. Extracellular adenosine activates AMP-dependent protein kinase (AMPK)
  2282. Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle
  2283. Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes
  2284. Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells
  2285. Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure
  2286. Fenofibrate activates AMPK and increases eNOS phosphorylation in HUVEC
  2287. … benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK …
  2288. AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes
  2289. Selective activation of AMPK‐PGC‐1α or PKB‐TSC2‐mTOR signaling can explain specific adaptive responses to endurance or resistance training‐like electrical …
  2290. Activation of AMPK by metformin inhibits TGF-β-induced collagen production in mouse renal fibroblasts
  2291. Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells
  2292. Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
  2293. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis
  2294. The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
  2295. Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP
  2296. Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes
  2297. Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
  2298. Oxidative stress induces GLUT4 translocation by activation of PI3‐K/Akt and dual AMPK kinase in cardiac myocytes
  2299. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
  2300. Cordycepin activates AMP‐activated protein kinase (AMPK) via interaction with the γ1 subunit
  2301. Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling
  2302. Adiponectin activation of AMPK disrupts leptin‐mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS‐3)
  2303. Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo
  2304. Ischemic preconditioning activates AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection
  2305. Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection
  2306. Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral …
  2307. AMPK α1 Activation Is Required for Stimulation of Glucose Uptake by Twitch Contraction, but Not by H2O2, in Mouse Skeletal Muscle
  2308. Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177
  2309. 20 (S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK
  2310. A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle
  2311. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells
  2312. Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes
  2313. Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels
  2314. Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK
  2315. ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK
  2316. Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: implications for cell metabolism and growth in skeletal muscle of …
  2317. … and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant …
  2318. Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
  2319. Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling
  2320. Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro
  2321. Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR
  2322. TAK1 activates AMPK-dependent cell death pathway in hydrogen peroxide-treated cardiomyocytes, inhibited by heat shock protein-70
  2323. Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin
  2324. Dietary folic acid activates AMPK and improves insulin resistance and hepatic inflammation in dietary rodent models of the metabolic syndrome
  2325. Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy
  2326. Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis
  2327. Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats
  2328. Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation
  2329. Hypothalamic inhibition of acetyl-CoA carboxylase stimulates hepatic counter-regulatory response independent of AMPK activation in rats
  2330. Isoquercitrin activates the AMP–activated protein kinase (AMPK) signal pathway in rat H4IIE cells
  2331. Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner
  2332. Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells
  2333. Energy depletion of bovine mammary epithelial cells activates AMPK and suppresses protein synthesis through inhibition of mTORC1 signaling
  2334. 4-O-methylascochlorin, methylated derivative of ascochlorin, stabilizes HIF-1α via AMPK activation
  2335. Apoptolidins A and C activate AMPK in metabolically sensitive cell types and are mechanistically distinct from oligomycin A
  2336. Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice
  2337. Regulation of yeast G protein signaling by the kinases that activate the AMPK homolog Snf1
  2338. PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the …
  2339. An extract of Artemisia dracunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation
  2340. trans-(−)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington …
  2341. Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis
  2342. Urocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle
  2343. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and …
  2344. Adenosine Activates AMPK to Phosphorylate Bcl-XL Responsible for Mitochondrial Damage and DIABLO Release in HuH-7 Cells
  2345. Gefitinib, an EGFR tyrosine kinase inhibitor, activates autophagy through AMPK in human lung cancer cells
  2346. Adiponectin activates endothelial nitric oxide synthase through AMPK signaling after subarachnoid hemorrhage
  2347. Angiotensin II activates AMPK for execution of apoptosis through energy-dependent and-independent mechanisms
  2348. Evodiamine activates AMPK and promotes adiponectin multimerization in 3T3-L1 adipocytes
  2349. PF-4708671 activates AMPK independently of p70S6K1 inhibition
  2350. Apoptotic cells activate AMP-activated protein kinase (AMPK) and inhibit epithelial cell growth without change in intracellular energy stores
  2351. Astrocyte elevated gene-1 activates AMPK in response to cellular metabolic stress and promotes protective autophagy
  2352. AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells
  2353. Liraglutide activates AMPK signaling and partially restores normal circadian rhythm and insulin secretion in pancreatic islets in diabetic mice
  2354. Chlorophyll a, an active anti-proliferative compound of Ludwigia octovalvis, activates the CD95 (APO-1/CD95) system and AMPK pathway in 3T3-L1 cells
  2355. The adenosine derivative 2′, 3′, 5′-tri-O-acetyl-N6-(3-hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo
  2356. Korean red ginseng activates AMPK in skeletal muscle and liver.
  2357. Clozapine activates AMP-activated protein kinase (AMPK) in C2C12 myotube cells and stimulates glucose uptake
  2358. CaMKKα activates AMPK signaling in mouse skeletal muscle in vivo
  2359. Unmetabolized fenofibrate, but not fenofibric acid, activates AMPK and inhibits the expression of phosphoenolpyruvate carboxykinase in hepatocytes
  2360. Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues
  2361. Estradiol activates AMPK through interaction with extrogen receptor beta (15.4)
  2362. Atorvastatin activates CaMKK-beta as an upstream kinase of AMPK in endothelium
  2363. The 1, 4-naphthoquinone derivative from Pyrola rotundifolia activates AMPK phosphorylation in C2C12 myotubes
  2364. Orexin-A activates hypothalamic ampk signaling through a Ca2+-dependent mechanism involving voltage-gated L-type calcium channel
  2365. Metformin activates duodenal AMPK and a neuronal network to lower glucose production
  2366. Red yeast barley reduces plasma glucose levels and activates AMPK phosphorylation in db/db mice
  2367. Pharmacological activation of 5’AMP-activated protein kinase (AMPK) in vivo acutely decreases blood glucose and chronically increases muscle GLUT4 in normal and …
  2368. Correction: Fenofibrate Improves Renal Lipotoxicity through Activation of AMPK-PGC-1α in db/db Mice
  2369. Curcumin Activates AMPK and SuppressesGluconeogenic Gene Expression in Hepatoma Cells
  2370. … Active Adiponectin Receptor Activator, Attenuates Myocardial Ischemia/Reperfusion Injury by AMPK-Mediated Autophagy and AMPK-Independent Anti-Apoptosis
  2371. Berberine, a natural plant product, activates AMPK with beneficial metabolic effects in diabetic and insulin resistant states
  2372. Conjugated linoleic acid (CLA) activates PGC‐1alpha via AMPK and SIRT1 in C2C12 myotubes
  2373. Resveratrol Activates AMP-Activated Protein Kinase (AMPK) by Increasing LKB1 Activity and AMP/ATP Ratio.
  2374. 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMPK signaling activation or glycolysis inhibition
  2375. Activation of AMP-activated protein kinase (AMPK) enhances Radiosensitization via inhibition of mTOR pathway in Rapamycin-resistant non-small cell lung cancer …
  2376. EMD387008, a New Antidiabetic Compound, Inhibits Hepatic Gluconeogenesis through Gluconeogenic Gene Regulation and AMPK Activation.
  2377. B04 AMPK activation alleviates phenotypes associated to the early phases of mutant polyQ cytoxicity
  2378. ATM signaling to mTORC1 in response to DNA damage independent of AMPK activation
  2379. Acute and chronic effects of AMPK activation on skeletal muscle fatty acid and carbohydrate metabolism
  2380. AMPK activation mimics glucose deprivation and induces cytotoxicity in ovarian cancer cells
  2381. AMPK activation is indispensable for the protective effects of caloric restriction on left ventricular function in the postinfarct myocardium
  2382. Research Article Amelioration of LPS-Induced Inflammation Response in Microglia by AMPK Activation
  2383. AMPK activation by adiponectin in renal tubules of control and diabetic rats
  2384. AMP-Activated Protein Kinase (AMPK) Activation and Signalling Following Neuronal Excitotoxicity
  2385. Skeletal muscle and whole-body regulation of substrate partitioning by nutritional and pharmacological AMPK activation.
  2386. Orignal Paper: AMPK activation and Adenine Nucleotide content in skeletal muscle following different types of high fat feeding
  2387. Retraction Note: Lipid metabolism disturbances and AMPK activation in prolonged propofol-sedated rabbits under mechanical ventilation
  2388. Abstract A79: Evidence that the antitumor effects of AMPK activation and crosstalk with the Akt pathway are dependent on the genetic profiles of human breast cancer …
  2389. ANTI-ANGIOGENIC EFFECTS OF METFORMIN, AN AMPK ACTIVATOR, ON HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
  2390. Nitrogen stress activates AMPK
  2391. Oxidative stress activates AMPK in cultured cells primarily
  2392. Inhibition of hepatic phosphatidylcholine synthesis by AICAR and phenformin is independent of AMP‐activated protein kinase (AMPK) activation.
  2393. Purinergic control of AMPK activation by ATP released through connexin 43 hemichannels: pivotal roles in hemichannel-mediated cell injury
  2394. Estradiol Activates AMPK through Interaction with Estrogen Receptor Beta
  2395. Triterpenoids extracted from bitter melon activate AMPK via a mechanism involving the upstream AMPK kinase CaMKKa/b
  2396. Atypical Antipsychotics Activate Hypothalamic AMPK
  2397. Brief intense interval exercise activates AMPK and p38
  2398. The role of AMP-activate protein kinase (AMPK) in the regulation of cardiac hypertrophy
  2399. Metformin activates AMPK and inhibits insulin secretion in MIN6 cell line culture
  2400. Berberine Activates AMPK in L6 Myotubes by a Mechanism Other Than Via Changes in ATP Levels.
  2401. Canagliflozin Potently Activates AMPK and Inhibits the Growth and Survival of Cancer Cells
  2402. Involvement of AMPK in the Beneficial Vascular Effect of a Non‐selective PPAR Activator in Aorta of Spontaneously Hypertensive Rats
  2403. Selective activation of AMPK in eddothelial cells intensifies high fat diet-induced non-alcoholic fatty liver disease
  2404. The Morphological Investigation Of The Mechanism Of Astragalus Polysaccharide Against Endoplasmic Reticulum Stress By Activation Of AMPK In TIID Rats
  2405. Activation of AMPK Actively Represses Steroid Hormone Synthesis in MA-10 Leydig Cells.
  2406. AMP-activated protein kinase (AMPK) regulates the activation process of hepatic stellate cells
  2407. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMPK, p38 MAPK, and PPARalpha
  2408. Adiponectin has anti-malignant potential in hepatocellular carcinoma (HCC) by activation of AMPK in HepG2 cells
  2409. Angiotensin II AT2 Receptor Activates AMPK For Execution Of Apoptosis Through Energy-Dependent And-Independent Mechanisms In Primary Pulmonary Artery …
  2410. Activation of AMPK results in ubiquitin-dependent degradation of Foxo1a, a pro-diabetic transcription factor regulating hepatic glucose production
  2411. Apelin Enhances Myocardial Glucose Uptake Through Activation of AMPK and Gq Signaling
  2412. Autophagy is stimulated by energy starvation through activation of AMPK and promotes survival of cardiac myocytes
  2413. Oxidative Stress Induces GLUT4 Translocation by dual AMPK Kinase Activation in Cardiac Myocytes
  2414. Rheb dynamics on lysosomal membranes determines mTORC1 activity after loss of p53 or activation of AMPK
  2415. Deletion of AMPK-Alpha2 intensifies the insulin-induced p70S6K activation in normoxic heart and the isoproterenol-induced ventricular hypertrophy
  2416. PT-1 selectively activates AMPK-1 complexes in mouse skeletal muscle, but activates all three subunit complexes in cultured human cells by inhibiting the …
  2417. Leptin activates α2 AMPK in C2C12 muscle cells through Atm and PI-3kinase/Nur77/CaMKKβ-dependent pathways.
  2418. SALICYLATE ACTIVATES AMPK AND SYNERGIZES WITH METFORMIN TO REDUCE THE SURVIVAL OF PROSTATE AND LUNG CANCERS EX VIVO THROUGH …
  2419. Cryptotanshinone Induces Cell Cycle Arrest and Autophagy of HepG2 Hepatoma via Activation of AMPK Signal Network
  2420. GW26-e0246 Metformin Activate AMPK, Inhibit GRP78 in liver and improve Insulin Sensitivity in Polycystic Ovarian Syndrome Rats
  2421. The NEDD8 Conjugation Pathway Inhibitor MLN4924 Activates AMPK and Induces The ER Stress/UPR-Mediated Cell Death Pathway In Acute Lymphoblastic …
  2422. Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to Antagonize Diet-induced Obesity
  2423. … Peroxide Activates AMP-Activated Protein Kinase in Endothelial Cells by Stimulating Ca2+/Calmodulin-Dependent Protein Kinase Kinase β, and Reveals a Critical Role for eNOS in AMPK …
  2424. Abstract# 2825: Cadmium activates mTOR pathway by upregulating NOX2 and downregulating PTEN and AMPK activity leading to apoptosis of neuronal cells
  2425. 0338: Glucagon-like peptide 1 or GLP-1 counteracts NADPH oxidase activation during hyperglycemia through an AMPK-dependent pathway in adult cardiomyocytes
  2426. 107 A Clinically Important Post-Translational Modification of CTRP9: Proteolytic Cleavage of CTRP9 Yields its Globular Domain, Which Activates AMPK
  2427. Glucagon-Like-Peptide-1 (GLP-1) Activates AMP-Activated Protein Kinase (AMPK) and Diminishes Inflammation in Human Aortic Endothelial Cells (HAECs)
  2428. The Mir-17∼ 92 Cluster Activates mTORC1 Signaling in MCL by Targeting Multiple Regulators of the LKB1/AMPK/mTOR Pathway
  2429. Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways
  2430. Deubiquitination and activation of AMPK by USP10
  2431. AMPK activation: Role in the signaling pathways of neuroinflammation and neurodegeneration
  2432. AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
  2433. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation
  2434. Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
  2435. AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression
  2436. AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
  2437. Inhibition of mitochondrial complex I improves glucose metabolism independently of AMPK activation
  2438. Genetic liver-specific AMPK activation protects against diet-induced obesity and NAFLD
  2439. Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers
  2440. AMPK activation reduces hepatic lipid content by increasing fat oxidation in vivo
  2441. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma
  2442. PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells
  2443. Desmoplasia suppression by metformin-mediated AMPK activation inhibits pancreatic cancer progression
  2444. Hypoxia, AMPK activation and uterine artery vasoreactivity
  2445. PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes patients
  2446. AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD+ elevation
  2447. AMPK activates LXRα and ABCA1 expression in human macrophages
  2448. Metformin activates AMPK through the lysosomal pathway
  2449. AMPK directly activates mTORC2 to promote cell survival during acute energetic stress
  2450. Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
  2451. FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process
  2452. Rosmarinic acid activates AMPK to inhibit metastasis of colorectal cancer
  2453. Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival
  2454. The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels
  2455. Green tea extract activates AMPK and ameliorates white adipose tissue metabolic dysfunction induced by obesity
  2456. AMPK activates FOXO3a and promotes neuronal apoptosis in the developing rat brain during the early phase after hypoxia-ischemia
  2457. Dietary luteolin activates browning and thermogenesis in mice through an AMPK/PGC1α pathway-mediated mechanism
  2458. Exercise activates lysosomal function in the brain through AMPK‐SIRT1‐TFEB pathway
  2459. Moderate Exercise Suppresses NF-κB Signaling and Activates the SIRT1-AMPK-PGC1α Axis to Attenuate Muscle Loss in Diabetic db/db Mice
  2460. miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone
  2461. Palmitate induces mitochondrial superoxide generation and activates AMPK in podocytes
  2462. Metformin activates the protective effects of the AMPK pathway in acute lung injury caused by paraquat poisoning
  2463. Omega-3 fatty acids-enriched fish oil activates AMPK/PGC-1α signaling and prevents obesity-related skeletal muscle wasting
  2464. Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice
  2465. Hesperetin is a potent bioactivator that activates SIRT1-AMPK signaling pathway in HepG2 cells
  2466. Mesenchymal stem cells-derived IL-6 activates AMPK/mTOR signaling to inhibit the proliferation of reactive astrocytes induced by hypoxic-ischemic brain damage
  2467. Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells
  2468. Targeting PP2A activates AMPK signaling to inhibit colorectal cancer cells
  2469. Naringin activates AMPK resulting in altered expression of SREBPs, PCSK9, and LDLR to reduce body weight in obese C57BL/6J mice
  2470. Rosmarinic acid, a rosemary extract polyphenol, increases skeletal muscle cell glucose uptake and activates AMPK
  2471. Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models
  2472. Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes
  2473. Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice
  2474. High uric acid activates the ROS-AMPK pathway, impairs CD68 expression and inhibits OxLDL-induced foam-cell formation in a human monocytic cell line …
  2475. Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival
  2476. Frontline Science: D1 dopaminergic receptor signaling activates the AMPK-bioenergetic pathway in macrophages and alveolar epithelial cells and reduces endotoxin …
  2477. PKA activates AMPK through LKB1 signaling in follicular thyroid cancer
  2478. Curcumin activates AMPK pathway and regulates lipid metabolism in rats following prolonged clozapine exposure
  2479. EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal …
  2480. Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes
  2481. Chrysanthemum indicum Inhibits Adipogenesis and Activates the AMPK Pathway in High-Fat-Diet-Induced Obese Mice
  2482. Compound 13 activates AMPK-Nrf2 signaling to protect neuronal cells from oxygen glucose deprivation-reoxygenation
  2483. Probing the enzyme kinetics, allosteric modulation and activation of α1-and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by …
  2484. Amarogentin, a secoiridoid glycoside, activates AMP-activated protein kinase (AMPK) to exert beneficial vasculo-metabolic effects
  2485. Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells
  2486. Phosphodiesterase 4 inhibitor activates AMPK-SIRT6 pathway to prevent aging-related adipose deposition induced by metabolic disorder
  2487. Butein activates autophagy through AMPK/TSC2/ULK1/mTOR pathway to inhibit IL-6 expression in IL-1β stimulated human chondrocytes
  2488. Perfluorooctanoic acid exposure alters polyunsaturated fatty acid composition, induces oxidative stress and activates the AKT/AMPK pathway in mouse epididymis
  2489. Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level
  2490. Zinc reduces hepatic lipid deposition and activates lipophagy via Zn2+/MTF‐1/PPARα and Ca2+/CaMKKβ/AMPK pathways
  2491. Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in …
  2492. Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes
  2493. PP2A catalytic subunit silence by microRNA-429 activates AMPK and protects osteoblastic cells from dexamethasone
  2494. The red pepper’s spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ
  2495. Knockdown of MAGEA6 activates AMP-activated protein kinase (AMPK) signaling to inhibit human renal cell carcinoma cells
  2496. Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia
  2497. Cichoric acid regulates the hepatic glucose homeostasis via AMPK pathway and activates the antioxidant response in high glucose-induced hepatocyte injury
  2498. A collagen domain–derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms
  2499. GSK621 activates AMPK signaling to inhibit LPS-induced TNFα production
  2500. Lactate administration activates the ERK 1/2, mTORC 1, and AMPK pathways differentially according to skeletal muscle type in mouse
  2501. Zanthoxylum alkylamides activate phosphorylated AMPK and ameliorate glycolipid metabolism in the streptozotocin-induced diabetic rats
  2502. Danzhi Qing’e (DZQE) activates AMPK pathway and regulates lipid metabolism in a rat model of perimenopausal hyperlipidaemia
  2503. The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism
  2504. PF-06409577 activates AMPK signaling to protect retinal pigment epithelium cells from UV radiation
  2505. Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis
  2506. Relaxin activates AMPK-AKT signaling and increases glucose uptake by cultured cardiomyocytes
  2507. TRB3 gene silencing activates AMPK in adipose tissue with beneficial metabolic effects in obese and diabetic rats
  2508. Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
  2509. AMPK activates DAPK2 to promote autophagy
  2510. Camptothecin activates SIRT1 to promote lipid catabolism through AMPK/FoxO1/ATGL pathway in C2C12 myogenic cells
  2511. Reserpine treatment activates AMP activated protein kinase (AMPK)
  2512. Correction to: Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells
  2513. CB2 receptor agonist JWH133 activates AMPK to inhibit growth of C6 glioma cells
  2514. The miR-17~ 92 cluster activates mTORC1 in mantle cell lymphoma by targeting multiple regulators in the STK11/AMPK/TSC/mTOR pathway
  2515. Voluntary wheel running activates Akt/AMPK/eNOS signaling cascades without improving profound endothelial dysfunction in mice deficient in α …
  2516. IL‐15 Activates Akt Independent of AMPK Signaling in Cardiomyocytes
  2517. Metformin Activates AMPK Signaling but Inhibits Mitophagy in the Mouse Heart
  2518. AdipoRon, pan‐adiponectin receptor agonist, activates mitochondrial metabolism via AMPK‐PGC1α pathway in the skeletal muscle
  2519. Corrigendum to “Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells”
  2520. Protective effects of Shenlingbaizhu powder against non-alcoholic fatty liver disease in rats through activation of SIRT3/AMPK/ACC signaling pathways
  2521. 166-LB: Canagliflozin but Not Empagliflozin Activates AMPK and Suppresses Colon Cancer Cell Growth
  2522. No Protective Effect of Constitutive Activation of AMPK in Endothelial Cells on Vascular Function in Aged Obese Mice but Augmented α1-Adrenergic Contractions in …
  2523. Corrigendum to” Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice”[Toxicol. Appl. Pharmacol …
  2524. … Activation by Pterostilbene Ameliorates Acute Doxorubicin Cardiotoxicity via Reducing Mitochondrial Oxidative Stress Through Enhancing Ampk and Sirt1 Cascades
  2525. PM2. 5 Exposure Induced Autophagy Activation via the ROS/AMPK/mTOR/ULK1 Signaling Axis in Macrophages
  2526. Mechanism of Activation of AMPK/P53-CyPD Signalling Pathway in Inhibiting Osteoblast Apoptosis Induced by Dexamethasone.
  2527. AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome
  2528. Regulation of lipid metabolism by strawberry extracts through AMP-activated protein kinase (AMPK) activation in HepG2 and 3T3-L1 cells
  2529. Activation of AMPK-Activated Protein Kinases Prevents Atrial Fibrillation
  2530. Glut5‐KD reduces blood pressure via increases phosphorylation of nNOS and decreases NADPH oxidase by AMPK activation in the NTS of fructose‐induced …
  2531. Abstract P5-04-08: Timing provides context for the paradoxical effects of AMPK activation in ER+ breast cancer: Suppressing growing tumors, but promoting dormant …
  2532. AMPK Protects against lps-induced endothelial hyperpermeability via activation of p38 mapk/hsp27 pathway and control of junctional proteins expression
  2533. Retraction: Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation
  2534. Mechanisms of activation and inhibition of the metabolic regulator AMP-activated protein kinase (AMPK)
  2535. Retracted: Safranal induces autophagy by AMPK activation and protects neurons against amyloid beta in Alzheimer’s disease
  2536. Metabolic stress in glaucoma engages early activation of the energy biosensor AMPK leading to neuronal dysfunction
  2537. FA-5, a novel AMP-activated protein kinase (AMPK) activator, as a new pharmacological tool for the management of bowel inflammation
  2538. Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK
  2539. Liver-specific activation of AMPK prevents steatosis on a high fructose diet
  2540. Metformin enhances intestinal epithelial health through activation of AMPK
  2541. The effects of NT-1044, a novel AMPK activator, on endometrial cancer cell proliferation, apoptosis, cell stress, and tumor growth
  2542. Antiproliferative effects of cimicifuga racemosa root extract Ze 450 mediated by inhibition of oxidative phosphorylation and indirect AMPK activation
  2543. 119-OR: Amplified Glucagon Response to Hypoglycemia following AMP-Activated Protein Kinase (AMPK) Activator R481 Treatment in Healthy Rats
  2544. 202 AMPK Activation Partially Restores the Anti-Contractile Effect of Perivascular Adipose Tissue in Female Offspring of Obese Rats
  2545. Extracellular citrate impacts hypothalamic mitochondrial function and activates AMPK
  2546. Adiponectin Through AMPK‐dependent Nuclear STAT3 Activation Facilitates Ischemic Postconditioning Cardioprotection
  2547. Balasubramide derivative 3C modulates microglia activation via CaMKKb-dependent AMPK/PGC-1a pathway in neuroinflammatory conditions
  2548. … Diabetes-induced Autophagic Flux Arrestment in Ischemic/Reperfused Heart by Adiponectin Receptor Activation Involves Both AMPK-Dependent and AMPK …
  2549. Mechanism of the AMPK-dependent activation of eukaryotic elongation factor 2 kinase (eEF-2K)
  2550. Elevation of Serum Fibroblast Growth Factor 21 in Patients With Acute Myocardial Infarction: A Potential Role of Ampk Activation Following Sympathetic Overdrive
  2551. Protective effect of Metformin against H2O2-induced oxidative damage in neuronal cells through activation of AMPK pathway
  2552. Abstract PD2-01: Clinically dormant ER+ breast tumors exhibit AMPK activation
  2553. P6070 Oxidized low-density lipoprotein, in contrast to inflammatory cytokines, activates AMPK-ACC signaling in human platelets
  2554. Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models
  2555. The inhibitory role of Kaempferol-3-O-rutinoside induced AMPK activation on the growth of human breast cancer cell lines
  2556. Cell contact activates AMP-Activated Protein Kinase (AMPK) through CaMKKβ and the GTPase Rac1
  2557. Salicylate sensitizes prostate cancer (PrCa) to radiotherapy; activation of AMPK and suppression of lipogenesis
  2558. Activation of the intracellular Ca++-AMPK pathway ameliorates apoptosis and improves autophagy in diabetic peripheral neuropathy
  2559. Carnosic acid activates AMPK, inhibits Akt and inhibits H1299 human lung cancer cell survival
  2560. P3812 AMPK/PGC1 activation by melatonin attenuates acute doxorubicin cardiotoxicity
  2561. Selenium-Binding Protein 1 Reduces Oxygen Consumption and Activates AMPK in Prostate Cancer Cells (OR11-04-19)
  2562. Estrogen Receptor alpha interferes with LKBl/AMPK/mTOR signaling activation in adiponectin-treated breast cancer cells
  2563. The Pro-Hypertrophic High Molecular Weight Fgf2 Activates Ampk or Erk by Engaging, Respectively, Fgfr1-Independent or Fgfr1-Dependent Pathways
  2564. P1. 03-03 Inhibition of H1299 Lung Cancer Cell Proliferation and Survival by Rosemary Extract Is Associated with AMPK Activation
  2565. Perfluorooctanoic Acid Exposure Alters Polyunsaturated Fatty Acid Composition, Induces Oxidative Stress and Activates the AKT/AMPK Pathway in Mouse …
  2566. IGF-1 activates AMPK to regulate mitochondrial fission/fusion proteins in adult rat sensory neurons
  2567. Abstract C122: NUC-7738, a novel ProTide modification of 3′-deoxyadenosine, activates AMPK and kills renal cancer cells in vitro
  2568. Resveratrol activates neuronal autophagy through AMPK in the ischemic brain
  2569. The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
  2570. AMPK activates Parkin independent autophagy and improves post sepsis immune defense against secondary bacterial lung infections
  2571. SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury
  2572. Metformin activates AMPK/SIRT1/NF-κB pathway and induces mitochondrial dysfunction to drive caspase3/GSDME-mediated cancer cell pyroptosis
  2573. Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development
  2574. High fat activates O-GlcNAcylation and affects AMPK/ACC pathway to regulate lipid metabolism
  2575. CARS senses cysteine deprivation to activate AMPK for cell survival
  2576. AMPK activates the Nrf2-Keap1 pathway to govern dendrite pruning via the insulin pathway in Drosophila
  2577. Rifampicin activates AMPK and alleviates oxidative stress in the liver as mediated with Nrf2 signaling
  2578. Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy
  2579. Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy
  2580. lncRNA Oip5‐as1 attenuates myocardial ischaemia/reperfusion injury by sponging miR‐29a to activate the SIRT1/AMPK/PGC1α pathway
  2581. A sulfonamide chalcone AMPK activator ameliorates hyperglycemia and diabetic nephropathy in db/db mice
  2582. Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway
  2583. Dihydroquercetin activates AMPK/Nrf2/HO-1 signaling in macrophages and attenuates inflammation in LPS-induced endotoxemic mice
  2584. Regulation of AMPK activation by extracellular matrix stiffness in pancreatic cancer
  2585. Alpha-lipoic acid activates AMPK to protect against oxidative stress and apoptosis in rats with diabetic peripheral neuropathy
  2586. Amyloid‐β activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk‐AMPK pathway
  2587. Ouabain impairs cancer metabolism and activates AMPK-Src signaling pathway in human cancer cell lines
  2588. AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells
  2589. l-Theanine Activates the Browning of White Adipose Tissue Through the AMPK/α-Ketoglutarate/Prdm16 Axis and Ameliorates Diet-Induced Obesity in Mice
  2590. Dapagliflozin ameliorates pancreatic injury and activates kidney autophagy by modulating the AMPK/mTOR signaling pathway in obese rats
  2591. Caffeic and chlorogenic acids synergistically activate browning program in human adipocytes: Implications of AMPK-and PPAR-mediated pathways
  2592. ZEA-induced autophagy in TM4 cells was mediated by the release of Ca2+ activates CaMKKβ-AMPK signaling pathway in the endoplasmic reticulum
  2593. Empagliflozin activates Sestrin2-mediated AMPK/mTOR pathway and ameliorates lipid accumulation in obesity-related nonalcoholic fatty liver disease
  2594. Glucose activates the primordial follicle through the AMPK/mTOR signaling pathway
  2595. miR-107 inhibition upregulates CAB39 and activates AMPK-Nrf2 signaling to protect osteoblasts from dexamethasone-induced oxidative injury and …
  2596. The novel non‐steroidal MR antagonist finerenone improves metabolic parameters in high‐fat diet‐fed mice and activates brown adipose tissue via AMPK‐ATGL …
  2597. CTRP3 activates the AMPK/SIRT1-PGC-1α pathway to protect mitochondrial biogenesis and functions in cerebral ischemic stroke
  2598. IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells
  2599. Mitochondrial ATP and Labile Fe (II) Pool Simultaneous Imaging in Ferroptosis Regulated by Energy-Stress Mediated AMPK Activation
  2600. Quercetin activates the Sestrin2/AMPK/SIRT1 axis to improve amyotrophic lateral sclerosis
  2601. Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts
  2602. Limonin, a novel AMPK activator, protects against LPS-induced acute lung injury
  2603. Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation
  2604. Dietary phosphorus reduced hepatic lipid deposition by activating Ampk pathway and beclin1 phosphorylation levels to activate lipophagy in tilapia …
  2605. Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance …
  2606. Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with …
  2607. Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis
  2608. Stevioside activates AMPK to suppress inflammation in macrophages and protects mice from LPS-induced lethal shock
  2609. Carnosic acid and carnosol activate AMPK, suppress expressions of gluconeogenic and lipogenic genes, and inhibit proliferation of HepG2 cells
  2610. Long-term caloric restriction activates the myocardial SIRT1/AMPK/PGC-1α pathway in C57BL/6J male mice
  2611. … -Resveratrol Attenuates Oxidative Stress, Adipogenesis and Insulin Resistance in In Vitro Models and High-Fat Diet-Induced Mouse Model via AMPK Activation
  2612. Punicalagin Activates AMPK/PGC‐1α/Nrf2 Cascade in Mice: The Potential Protective Effect against Prenatal Stress
  2613. The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
  2614. PF-06409577 activates AMPK signaling and inhibits osteosarcoma cell growth
  2615. Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis
  2616. Broccoli-Derived Glucoraphanin Activates AMPK/PGC1α/NRF2 Pathway and Ameliorates Dextran-Sulphate-Sodium-Induced Colitis in Mice
  2617. LncRNA GAS5 activates the AMPK pathway in peripheral blood mononuclear cells derived from rheumatoid arthritis patients
  2618. Maslinic acid activates renal AMPK/SIRT1 signaling pathway and protects against diabetic nephropathy in mice
  2619. A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway
  2620. A subset of VEGFR‐TKIs activates AMPK in LKB1‐mutant lung cancer
  2621. Rosemary extract increases neuronal cell glucose uptake and activates AMPK
  2622. Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway
  2623. Propofol activates AMPK to inhibit the growth of HepG2 cells in vitro and hepatocarcinogenesis in xenograft mouse tumor models by inducing autophagy
  2624. Porcine epidemic diarrhoea virus (PEDV) infection activates AMPK and JNK through TAK1 to induce autophagy and enhance virus replication
  2625. Exercise activates AMPK signaling: Impact on glucose uptake in the skeletal muscle in aging
  2626. Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle
  2627. Xanthohumol protect against acetaminophen-induced hepatotoxicity via Nrf2 activation through the AMPK/Akt/GSK3β pathway
  2628. The mechanisms of hydroxy-α-sanshool from Zanthoxyum bungeanum maxim activates AMPK-HIF1-PKM2 pathway to fix the obesity
  2629. Ming-mu-di-huang-pill activates SQSTM1 via AMPK-mediated autophagic KEAP1 degradation and protects RPE cells from oxidative damage
  2630. WSSV exploits AMPK to activate mTORC2 signaling for proliferation by enhancing aerobic glycolysis
  2631. Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis
  2632. Three-Dimensional Matrix Stiffness Activates the Piezo1-AMPK-Autophagy Axis to Regulate the Cellular Osteogenic Differentiation
  2633. Linggui Zhugan Decoction activates the SIRT1-AMPK-PGC1α signaling pathway to improve mitochondrial and oxidative damage in rats with chronic heart …
  2634. Camptothecin Inhibits Neddylation to Activate the Protective Autophagy Through NF-κB/AMPK/mTOR/ULK1 Axis in Human Esophageal Cancer Cells
  2635. Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells
  2636. … of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK …
  2637. Epidermal growth factor activates EGFR/AMPK signalling to up-regulate the expression of SGLT1 and GLUT2 to promote intestinal glucose absorption in …
  2638. Diosmetin inhibits apoptosis and activates AMPK‐induced autophagy in myocardial damage under hypoxia environment
  2639. 4‐O‐methylascochlorin activates autophagy by activating AMPK and suppressing c‐Myc in glioblastoma
  2640. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy
  2641. … galactooligosaccharide intervention alters the metabolic profile, improves the antioxidant capacity of mitochondria and activates the AMPK/Nrf2 signaling pathway in …
  2642. Atomoxetine and Fluoxetine Activate AMPK-ACC-CPT1 Pathway in Human SH-SY5Y and U-87 MG Cells
  2643. DJ-1 activates the AMPK/mTOR pathway by binding RACK1 to induce autophagy and protect the myocardium from ischemia/hypoxia injury
  2644. Hedgehog signal activates AMPK via Smoothened to promote autophagy and lipid degradation in hepatocytes
  2645. Rosemary extract activates AMPK, inhibits mTOR and attenuates the high glucose and high insulin-induced muscle cell insulin resistance
  2646. IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR in hepatocytes, the stroma and cancer cells
  2647. Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis
  2648. … , a sulfur compound in aged garlic extract, alleviates cold‑induced reduction in peripheral blood flow in rat via activation of the AMPK/eNOS/NO pathway
  2649. β-hydroxybutyrate and hydroxycarboxylic acid receptor 2 agonists activate the AKT, ERK and AMPK pathways, which are involved in bovine neutrophil …
  2650. Activation of SNF1/AMPK mediates the mitochondrial derepression, resistance to oxidative stress and increased lifespan of cells lacking the phosphatase Sit4p
  2651. Whole body vibration activates AMPK/CPT1 signaling pathway of skeletal muscle in young and aging mice based on metabolomics study
  2652. … of genistein on the production performance and lipid metabolism disorders in laying hens with fatty liver hemorrhagic syndrome by activation of the GPER-AMPK …
  2653. Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes
  2654. Salvianolic acid C promotes osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporotic rats through activation of AMPK/SIRT1 pathway
  2655. A Box-Behnken design for optimal green extraction of compounds from olive leaves that potentially activate the AMPK pathway
  2656. Chronic Activation of AMPK Induces Mitochondrial Biogenesis through Differential Phosphorylation and Abundance of Mitochondrial Proteins in Dictyostelium …
  2657. Anti-Obesity Effect of Dyglomera® Is Associated with Activation of the AMPK Signaling Pathway in 3T3-L1 Adipocytes and Mice with High-Fat Diet-Induced …
  2658. 3H-1, 2-dithiole-3-thione protects lens epithelial cells against fructose-induced epithelial-mesenchymal transition via activation of AMPK to eliminate AKR1B1-induced …
  2659. Identification of Stabilization of Malvid Anthocyanins and Antioxidant Stress Activation via the AMPK/SIRT1 Signaling Pathway
  2660. Carbon monoxide exposure activates ULK1 via AMPK phosphorylation in murine embryonic fibroblasts
  2661. AMPK activation induces RALDHhigh tolerogenic dendritic cells through rewiring of glucose and lipid metabolism
  2662. Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation
  2663. Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
  2664. Role of inorganic polyphosphates in the activation of AMPK in models of Alzheimer’s disease
  2665. The Protective Effect of 11-Keto-β-Boswellic Acid against Diabetic Cardiomyopathy in Rats Entails Activation of AMPK
  2666. Activation of FXR receptor reduces damage of ET-1 on H9C2 cardiomyocytes by activating AMPK signaling pathway.
  2667. Moving towards isoform-specific AMPK activation
  2668. EP16. 04-008 Cytotoxic Effects of Carnosic Acid Are Mediated by Induction of Autophagy and Activation of Sestrin-2/LKB1/AMPK Signalling in H1299 NSCLC Cells
  2669. Effects of AMPK activator and inhibitor on penetrating Transplantation
  2670. Dapagliflozin activates AMPK to attenuate cardiac dysfunction and oxidative stress under hypoxia/reoxygenation-caused damage
  2671. 25-Hydroxycholesterol Regulates Lysosome AMPK Activation and Metabolism Reprograming to Educate Immunosuppressive Macrophages
  2672. Adiponectin inhibits palmitic acid-induced NLRP3 inflammasome activation in hepatocytes through AMPK-JNK/ErK1/2-NFκB/ROS signaling pathways
  2673. AMPK Activates ULK1 in Skeletal Muscle Without Increasing Markers of Autophagy
  2674. The Antitumor Effect of Capsaicin on Prostate Cancer Cells Depends on AMPK Activation Through LKB1 Kinase and TRPV1 Receptor
  2675. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to energy sensing and autophagy
  2676. Correction to: context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity
  2677. Heat-Killed Lactiplantibacillus plantarum APSulloc 331261 Enhances Lipid Catabolism Through AMPK Activation in HepG2 Cells
  2678. The Effects of NT-1044, a Novel AMPK Activator, on Endometrial Cancer Cell Proliferation, Apoptosis, Cell Stress and In Vivo Tumor Growth
  2679. Duodenal-jejunal bypass surgery activates eNOS and enhances antioxidant system by activating AMPK pathway to improve oxidative stress diabetic cardiomyopathy
  2680. β-aminoisobutyric Acid, a Metabolite of BCAA, Activates the AMPK/Nrf-2 Pathway to Prevent Ferroptosis and Ameliorates Lung Ischemia-Reperfusion Injury
  2681. Sitagliptin via the activation of AMPK/eNOS signaling improves vascular endothelial function by suppressing Creb5/lncRNA ENSMUST00000213271 axis in obese …
  2682. AMPK activation alleviated dextran sulfate sodium-induced colitis by inhibiting ferroptosis
  2683. AICAR-induced activation of AMPK inhibits the migration of TSCC cells by targeting ZO-1
  2684. Dietary cannabidiol activates PKA/ERK/AMPK signaling and attenuates chronic inflammation and leaky gut in DSS-induced colitis mice
  2685. Comparative study of callus culture and leaves of Thunbergia laurifolia for their bioactive constituents and the activation of AMPK and GLUT‐dependent glucose …
  2686. Atherosclerosis is attenuated by acacetin via Sirt1-mediated activation of AMPK/Sirt3 signals in diabetic ApoE−/− mice
  2687. … sensing hypothalamic GT1-7 neuronal cells and pancreatic αTC1. 9 α-cells to examine the effect of R481 on AMPK pathway activation and cellular metabolism …
  2688. Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy
  2689. AMPK blocks chromatin activation and consequent R-loop formation to protect genome stability following acute starvation
  2690. Increased macrophage activation mediated by caspase recruitment domain 6 knockdown through negatively targeting AMPK
  2691. Nandrolone supplementation promotes AMPK activation and divergent 18 [FDG] PET brain connectivity in adult and aged mice
  2692. Herbal medicine of Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production to activate AMPK in hepatocytes in therapy of type 2 diabetes
  2693. Exosomal microRNA-122 from HCC inhibits hepatic stellate cell fibrosis activation via AMPK signaling.
  2694. 386-P: Chronic Treatment with the Direct AMPK Activator PXL770 Improves Cardiac, Vascular, and Renal Function in Rodents with Diabetes-Related Cardiorenal …
  2695. Quercetin activates autophagy suppresses apoptosis, inflammation and cartilage matrix degradation in LPS-induced chondrocytes through targeting AMPK/mTOR …
  2696. Metformin activates AMPK to alleviate acute fulminant hepatitis induced by concanavalin A in mice
  2697. … INDUCES POSTMENOPAUSAL HYPERTENSIVE HYPERTROPHY THROUGH INHIBITING THE ACTIVATION OF AMPK-FOXO1/MURF1 SIGNALING PATHWAY
  2698. AICAR activates AMPK to regulate STAT3 nuclear translocation and phosphorylation and iNOS expression in inflammatory pain
  2699. 199-OR: Exercise Decreases Mouse and Human Islet Senescence through Glucagon-Mediated AMPK Activation
  2700. Citrulline and arginine activate eNOS via AMPK and increase retinal endothelial cell permeability
  2701. Themes: Title: Anti-angiogenic effects of Metformin, an AMPK activator, on Human Umbilical Vein Endothelial Cells
  2702. Metformin and Carvedilol ameliorate isoprenaline-induced myocardial infarction in non-diabetic rats through AMPK activation and suppression of apoptosis
  2703. The Role of Adenosine Monophosphate Protein Kinase (AMPK) Activation In Francisella tularensis Intracellular Replication
  2704. Salvianolic acid A activates AMPK and SIRT1 to reduce palmitic acid-induced lipotoxicity in hepatocyte
  2705. Correction: EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal …
  2706. … Factor-κB (NF-κB)-Regulated Adenosine Monophosphate Activated Protein Kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Signaling Pathway to Activate …

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