MACROAUTOPHAGY

  1. The machinery of macroautophagy
  2. Eaten alive: a history of macroautophagy
  3. The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy
  4. Huntington’s disease pathogenesis is modified in vivo by Alfy/Wdfy3 and selective macroautophagy
  5. Discovery of Atg5/Atg7-independent alternative macroautophagy
  6. Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells
  7. BACE 2 degradation mediated by the macroautophagy–lysosome pathway
  8. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-β, and Bcl-2
  9. Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
  10. Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
  11. Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer’s disease
  12. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
  13. Inhibition of macroautophagy triggers apoptosis
  14. Regulation of presynaptic neurotransmission by macroautophagy
  15. An overview of macroautophagy in yeast
  16. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
  17. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
  18. Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells
  19. Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy
  20. HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy
  21. Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
  22. α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
  23. Huntingtin functions as a scaffold for selective macroautophagy
  24. Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
  25. Overview of macroautophagy regulation in mammalian cells
  26. HspB8 chaperone activity toward poly (Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy
  27. Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes
  28. Degradation of amyotrophic lateral sclerosis-linked mutant Cu, Zn-superoxide dismutase proteins by macroautophagy and the proteasome
  29. Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
  30. Macroautophagy regulates energy metabolism during effector T cell activation
  31. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
  32. Posttranslational modification of autophagy-related proteins in macroautophagy
  33. Regulation of macroautophagy by mTOR and Beclin 1 complexes
  34. Aggrephagy: selective disposal of protein aggregates by macroautophagy
  35. Altered macroautophagy in the spinal cord of SOD1 mutant mice
  36. Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
  37. Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes
  38. Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
  39. Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy*♦
  40. Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
  41. Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
  42. SNARE proteins are required for macroautophagy
  43. A role for macroautophagy in protection against 4-hydroxytamoxifen–induced cell death and the development of antiestrogen resistance
  44. Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells
  45. Mitochondrial morphology in mitophagy and macroautophagy
  46. … pathology in A53T α-synuclein cell model of Parkinson’s disease through the downregulation of mTOR/p70S6K signaling and the recovery of macroautophagy
  47. A LRRK2-dependent endophilinA phosphoswitch is critical for macroautophagy at presynaptic terminals
  48. Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells
  49. Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
  50. Lipofuscin: formation, effects and role of macroautophagy
  51. GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy
  52. Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization
  53. Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways
  54. Macroautophagy and chaperone‐mediated autophagy are required for hepatocyte resistance to oxidant stress
  55. Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus*♦
  56. Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infection
  57. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes
  58. Involvement of macroautophagy in the dissolution of neuronal inclusions
  59. The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases
  60. Piecemeal microautophagy of the nucleus requires the core macroautophagy genes
  61. The mechanism and physiological function of macroautophagy
  62. Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
  63. A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration
  64. Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins
  65. Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum
  66. Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway
  67. New insights into the mechanisms of macroautophagy in mammalian cells
  68. Mammalian macroautophagy at a glance
  69. TNF-α induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells
  70. Macroautophagy is deregulated in murine and human lupus T lymphocytes
  71. Dictyostelium macroautophagy mutants vary in the severity of their developmental defects
  72. Ageing-related changes in the in vivo function of rat liver macroautophagy and proteolysis
  73. Inhibition of LRRK2 kinase activity stimulates macroautophagy
  74. Cytosolic LC3 ratio as a quantitative index of macroautophagy
  75. Macroautophagy in CNS health and disease
  76. Neuronal macroautophagy: from development to degeneration
  77. Molecular machinery of macroautophagy and its deregulation in diseases
  78. Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy
  79. Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum
  80. Atg5 disassociates the V1V0-ATPase to promote exosome production and tumor metastasis independent of canonical macroautophagy
  81. The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway
  82. miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy via transforming growth factor-β/Smad4 pathway
  83. Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells
  84. The phospholipase D1 pathway modulates macroautophagy
  85. Macroautophagy versus mitochondrial autophagy: a question of fate?
  86. Macroautophagy proteins control MHC class I levels on dendritic cells and shape anti-viral CD8+ T cell responses
  87. Crosstalk between macroautophagy and chaperone-mediated autophagy: implications for the treatment of neurological diseases
  88. Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging
  89. Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy
  90. Calpain is required for macroautophagy in mammalian cells
  91. Induction of macroautophagy by exogenously introduced calcium
  92. Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer’s disease
  93. Macroautophagy is defective in mucolipin-1-deficient mouse neurons
  94. ATP13A2 regulates mitochondrial bioenergetics through macroautophagy
  95. Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury
  96. Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy
  97. Macroautophagy signaling and regulation
  98. Protein misfolding disorders and macroautophagy
  99. A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells
  100. Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus
  101. mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
  102. Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display
  103. Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation
  104. The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically
  105. A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions
  106. Genetic aberrations in macroautophagy genes leading to diseases
  107. Fasting activates macroautophagy in neurons of Alzheimer’s disease mouse model but is insufficient to degrade amyloid-beta
  108. Oxidative stress induces macroautophagy of amyloid β-protein and ensuing apoptosis
  109. Regulation of macroautophagy in Saccharomyces cerevisiae
  110. The calcineurin-TFEB-p62 pathway mediates the activation of cardiac macroautophagy by proteasomal malfunction
  111. Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death
  112. Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway
  113. Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells
  114. Analysis of macroautophagy by immunohistochemistry
  115. Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration
  116. Macroautophagy proteins assist Epstein Barr virus production and get incorporated into the virus particles
  117. Alterations in ROS activity and lysosomal pH account for distinct patterns of macroautophagy in LINCL and JNCL fibroblasts
  118. The LRRK2–macroautophagy axis and its relevance to Parkinson’s disease
  119. HO‐1‐mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues
  120. Macroautophagy is regulated by the UPR–mediator CHOP and accentuates the phenotype of SBMA mice
  121. Prebiotic lactulose ameliorates the cognitive deficit in Alzheimer’s disease mouse model through macroautophagy and chaperone-mediated autophagy pathways
  122. Macroautophagy-Mediated Degradation of Whole Nuclei in the Filamentous Fungus Aspergillus oryzae
  123. Immunohistochemical analysis of macroautophagy: recommendations and limitations
  124. A comparative map of macroautophagy and mitophagy in the vertebrate eye
  125. Macroautophagy is not directly involved in the metabolism of amyloid precursor protein
  126. A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and …
  127. Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity
  128. Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo
  129. Function and regulation of macroautophagy in plants
  130. Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats
  131. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation
  132. Impairment of macroautophagy in dopamine neurons has opposing effects on parkinsonian pathology and behavior
  133. Nutrient control of macroautophagy in mammalian cells
  134. Macroautophagy and aging: The impact of cellular recycling on health and longevity
  135. Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts
  136. Macroautophagy in quiescent and senescent cells: a pathway to longevity?
  137. Does Huntingtin play a role in selective macroautophagy?
  138. Macroautophagy and chaperone-mediated autophagy in heart failure: the known and the unknown
  139. Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
  140. Induction of macroautophagy by heat
  141. Downregulation of ATG5-dependent macroautophagy by chaperone-mediated autophagy promotes breast cancer cell metastasis
  142. NRBF2 regulates macroautophagy as a component of Vps34 Complex I
  143. Ketosis may promote brain macroautophagy by activating Sirt1 and hypoxia-inducible factor-1
  144. Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma
  145. Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts
  146. Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy
  147. Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes
  148. Sensing membrane curvature in macroautophagy
  149. 3, 4‐dimethoxystilbene, a resveratrol derivative with anti‐angiogenic effect, induces both macroautophagy and apoptosis in endothelial cells
  150. Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy
  151. The macroautophagy machinery in MHC restricted antigen presentation
  152. Functional macroautophagy induction by influenza A virus without a contribution to major histocompatibility complex class II-restricted presentation
  153. Bay41-4109-induced aberrant polymers of hepatitis b capsid proteins are removed via STUB1-promoted p62-mediated macroautophagy
  154. A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy
  155. Macroautophagy and selective mitophagy ameliorate chondrogenic differentiation potential in adipose stem cells of equine metabolic syndrome: new findings …
  156. Ypt1/Rab1 regulates Hrr25/CK1δ kinase activity in ER–Golgi traffic and macroautophagy
  157. Regulation of ER stress-induced macroautophagy by protein kinase C
  158. C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy
  159. Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy
  160. The RAB GTPase RAB18 modulates macroautophagy and proteostasis
  161. Short and long sleeping mutants reveal links between sleep and macroautophagy
  162. ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1
  163. p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy
  164. NSAIDs disrupt intestinal homeostasis by suppressing macroautophagy in intestinal epithelial cells
  165. Proteasome malfunction activates macroautophagy in the heart
  166. Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules
  167. Diversity of signaling controls of macroautophagy in mammalian cells
  168. Viral interactions with macroautophagy: a double-edged sword
  169. Degradation of protein translation machinery by amino acid starvation-induced macroautophagy
  170. Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways
  171. lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR‑34a/mTOR/SIRT1 …
  172. JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells
  173. Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells
  174. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy
  175. Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway
  176. Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae
  177. Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity
  178. Induction of autophagic flux by amino acid deprivation is distinct from nitrogen starvation-induced macroautophagy
  179. Macroautophagy: the key ingredient to a healthy diet?
  180. Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson’s disease brains with Lewy body pathology
  181. KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral‐driven …
  182. Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK
  183. SnapShot: macroautophagy
  184. The selective degradation of sirtuins via macroautophagy in the MPP+ model of Parkinson’s disease is promoted by conserved oxidation sites
  185. Disruption of microtubules in plants suppresses macroautophagy and triggers starch excess-associated chloroplast autophagy
  186. The role of macroautophagy and chaperone-mediated autophagy in the pathogenesis and management of hepatocellular carcinoma
  187. Serum supplementation during bovine embryo culture affects their development and proliferation through macroautophagy and endoplasmic reticulum stress …
  188. Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling
  189. Gigantic macroautophagy in programmed nuclear death of Tetrahymena thermophila
  190. Global proximity interactome of the human macroautophagy pathway
  191. Unravelling the relationship between macroautophagy and mitochondrial ROS in cancer therapy
  192. The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells
  193. Quantitative assessment of the degradation of aggregated TDP‐43 mediated by the ubiquitin proteasome system and macroautophagy
  194. mTOR suppresses macroautophagy during striatal postnatal development and is hyperactive in mouse models of autism spectrum disorders
  195. Methylene blue induces macroautophagy through 5′ adenosine monophosphate-activated protein kinase pathway to protect neurons from serum …
  196. Evidence of impaired macroautophagy in human degenerative cervical myelopathy
  197. Unfolded protein response and macroautophagy in Alzheimer’s, Parkinson’s and prion diseases
  198. The parkinsonian LRRK2 R1441G mutation shows macroautophagy-mitophagy dysregulation concomitant with endoplasmic reticulum stress
  199. Induction of macroautophagy by overexpression of the Parkinson’s disease‐associated GPR37 receptor
  200. Analyses of Gα-interacting protein and activator of G-protein-signaling-3 functions in macroautophagy
  201. Nutraceutical and dietary strategies for up-regulating macroautophagy
  202. Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor
  203. Macroautophagy and its role in nutrient homeostasis
  204. Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion
  205. Macroautophagy and ERK phosphorylation counteract the anti-proliferative effect of proteasome inhibitor in gastric cancer cells
  206. Prolyl oligopeptidase acts as a link between chaperone-mediated autophagy and macroautophagy
  207. Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions
  208. The involvement of macroautophagy in aging and anti-aging interventions
  209. Shaping dendritic spines in autism spectrum disorder: mTORC1-dependent macroautophagy
  210. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic …
  211. Macroautophagy in endogenous processing of self-and pathogen-derived antigens for MHC class II presentation
  212. Modulating macroautophagy: a neuronal perspective
  213. Classical macroautophagy in Lobivia rauschii (Cactaceae) and possible plastidial autophagy in Tillandsia albida (Bromeliaceae) tapetum cells
  214. The role of macroautophagy in development of filamentous fungi
  215. Chaperon-mediated autophagy can regulate diquat-induced apoptosis by inhibiting α-synuclein accumulation cooperatively with macroautophagy
  216. Highly dynamic changes in the activity and regulation of macroautophagy in hearts subjected to increased proteotoxic stress
  217. … Deoxynivalenol Aggravates Intestinal Inflammation and Barrier Dysfunction Induced by Enterotoxigenic Escherichia coli Infection through Activating Macroautophagy …
  218. Regulation of macroautophagy in amiodarone‐induced pulmonary fibrosis
  219. Targeting Beclin 1 for viral subversion of macroautophagy
  220. Macroautophagy in dendritic cells controls the homeostasis and stability of regulatory T cells
  221. Urate promotes SNCA/α-synuclein clearance via regulating mTOR-dependent macroautophagy
  222. Targeting macroautophagy as a therapeutic opportunity to treat parkinson’s disease
  223. Macroautophagy and normal aging of the nervous system: Lessons from animal models
  224. Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils
  225. Manipulation of selective macroautophagy by pathogens at a glance
  226. Macroautophagy-aided elimination of chromatin: sorting of waste, sorting of fate?
  227. Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes
  228. Mitofusin2, a rising star in acute‐on‐chronic liver failure, triggers macroautophagy via the mTOR signalling pathway
  229. Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor‐dependent apoptosis
  230. T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8+ CD28+ T cells but not in CD8+ CD28− T cells
  231. Strain-dependent effect of macroautophagy on abnormally folded prion protein degradation in infected neuronal cells
  232. The impact of aging on macroautophagy in the pre-ovulatory mouse oocyte
  233. Liraglutide improves the survival of INS-1 cells by promoting macroautophagy
  234. Role of macroautophagy in nutrient homeostasis during fungal development and pathogenesis
  235. Ferritin-stimulated lipid peroxidation, lysosomal leak, and macroautophagy promote lysosomal “metastability” in primary hepatocytes determining in vitro cell survival
  236. The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport
  237. IL-1β-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK
  238. SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy
  239. Alternative macroautophagy and mitophagy
  240. Stimulation of macroautophagy can rescue older cells from 8-OHdG mtDNA accumulation: a safe and easy way to meet goals in the SENS agenda
  241. Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic …
  242. Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy
  243. Sphingolipids in macroautophagy
  244. The macroautophagy machinery in endo-and exocytosis
  245. Regulation of innate immunity by the molecular machinery of macroautophagy
  246. Macroautophagy in sporadic and the genetic form of Parkinson’s disease with the A53T α-synuclein mutation
  247. Signalphagy: scheduled signal termination by macroautophagy
  248. Inhibitory effect of intracellular lipid load on macroautophagy
  249. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells
  250. E46K mutant α-synuclein is degraded by both proteasome and macroautophagy pathway
  251. Perturbation of bulk and selective macroautophagy, abnormal UPR activation and their interplay pave the way to immune dysfunction, cancerogenesis and …
  252. Signal transduction pathways in macroautophagy
  253. Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway
  254. Macroautophagy: protector in the diabetes drama?
  255. Macroautophagy in T lymphocyte development and function
  256. Macroautophagy as a pathomechanism in sporadic inclusion body myositis
  257. Macroautophagy in homeostasis of pancreatic β-cell
  258. Macroautophagy: a mechanism for mediating cell death or for promoting cell survival?
  259. CCZ1, MON1 and YPT7 genes are involved in pexophagy, the Cvt pathway and non‐specific macroautophagy in the methylotrophic yeast Pichia pastoris
  260. Subcellular localization of the Gαi3 protein and G alpha interacting protein, two proteins involved in the control of macroautophagy in human colon cancer HT-29 cells
  261. … of exercise preconditioning involving heat shock protein 70 and concurrent autophagy: a potential chaperone-assisted selective macroautophagy effect
  262. Amino acid sensory complex proteins in mTORC1 and macroautophagy regulation
  263. Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model …
  264. Genetic enhancement of macroautophagy in vertebrate models of neurodegenerative diseases
  265. Non-canonical functions of macroautophagy proteins during endocytosis by myeloid antigen presenting cells
  266. ATG101 single-stranded antisense RNA-loaded triangular DNA nanoparticles control human pulmonary endothelial growth via regulation of cell macroautophagy
  267. … 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 …
  268. Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism
  269. Beclin 1 enhances proteasome inhibition-mediated cytotoxicity of thyroid cancer cells in macroautophagy-independent manner
  270. The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy
  271. Macroautophagy can press a brake on presynaptic neurotransmission
  272. Septins are involved at the early stages of macroautophagy in S. cerevisiae
  273. Macroautophagy regulation during HIV-1 infection of CD4+ T cells and macrophages
  274. Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization
  275. An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
  276. Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons
  277. Inhibition of macroautophagy and proteolysis in the isolated rat hepatocyte by a nontransportable derivative of the multiple antigen peptide Leu8-Lys4-Lys2-Lys-beta …
  278. The sorting nexin FgAtg20 is involved in the Cvt pathway, non‐selective macroautophagy, pexophagy and pathogenesis in Fusarium graminearum
  279. The impact of macroautophagy on CD8+ T‐cell‐mediated antiviral immunity
  280. Caffeine induces macroautophagy and confers a cytocidal effect on food spoilage yeast in combination with benzoic acid
  281. Macroautophagy
  282. The proteasome subunit RPN10 functions as a specific receptor for degradation of the 26S proteasome by macroautophagy in Arabidopsis
  283. Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy
  284. Macroautophagy in immunity and tolerance
  285. The insufficiency of ATG4A in macroautophagy
  286. Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells
  287. Vitamin E as a novel enhancer of macroautophagy in rat hepatocytes and H4-II-E cells
  288. Macroautophagy and microautophagy in relation to vacuole formation in mesophyll cells of Dendrobium tepals
  289. Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy
  290. Macroautophagy supports sonic Hedgehog signaling by promoting Patched1 degradation
  291. Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy
  292. Antigen processing by macroautophagy for MHC presentation
  293. Visualization and quantitation of abundant macroautophagy in virus-infected cells by confocal three-dimensional fluorescence imaging
  294. Role of Macroautophagy in Mammalian Male Reproductive Physiology
  295. The significance of macroautophagy in health and disease
  296. TP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy
  297. Alfy-dependent elimination of aggregated proteins by macroautophagy: can there be too much of a good thing?
  298. Limited effects of dysfunctional macroautophagy on the accumulation of extracellularly derived α-synuclein in oligodendroglia: implications for MSA …
  299. Alternative macroautophagy
  300. Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy
  301. The dynamic proteome of oligodendrocyte lineage differentiation features planar cell polarity and macroautophagy pathways
  302. Macroautophagy in mammalian cells
  303. Thymic epithelial cells use macroautophagy to turn their inside out for CD4 T cell tolerance
  304. CNTNAP2 Protein Is Degraded by the Ubiquitin–Proteasome System and the Macroautophagy-Lysosome Pathway
  305. H1-antihistamines induce vacuolation in astrocytes through macroautophagy
  306. Antigen cross-priming of cell-associated proteins is enhanced by macroautophagy within the antigen donor cell
  307. Correction: Corrigendum: Discovery of Atg5/Atg7-independent alternative macroautophagy
  308. Time course of ubiquitin-proteasome and macroautophagy-lysosome pathways in skeletal muscle in rats with heart failure
  309. Parkin is dispensable for mitochondrial function, but its ubiquitin ligase activity is critical for macroautophagy and neurotransmitters: therapeutic potential beyond …
  310. AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy
  311. Beclin-1/LC3-II dependent macroautophagy was uninfluenced in ischemia-challenged vascular endothelial cells
  312. Zika virus: Critical crosstalk between pathogenesis, cytopathic effects, and macroautophagy
  313. Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells
  314. A panel of macroautophagy markers in lymphomonocytes of patients with amyotrophic lateral sclerosis
  315. Proteasome malfunction activates the PPP3/calcineurin-TFEB-SQSTM1/p62 pathway to induce macroautophagy in the heart
  316. Biogenesis of Autophagosome in Trichomonas vaginalis during Macroautophagy Induced by Rapamycin‐treatment and Iron or Glucose Starvation Conditions
  317. Macroautophagy during innate immune activation
  318. Protective macroautophagy is involved in vitamin e succinate effects on human gastric carcinoma cell line SGC-7901 by inhibiting mTOR axis phosphorylation
  319. Macroautophagy and the oncogene-induced senescence
  320. Tid1, the mammalian homologue of Drosophila tumor suppressor Tid56, mediates macroautophagy by interacting with Beclin1-containing autophagy protein …
  321. Quantitative assay of macroautophagy using Pho8△ 60 assay and GFP-cleavage assay in yeast
  322. Sequential steps of macroautophagy and chaperone-mediated autophagy are involved in the irreversible process of posterior silk gland histolysis during …
  323. Yeast phospholipase D, Spo14, is not required for macroautophagy
  324. Macroautophagy of aggregation-prone proteins in neurodegenerative disease
  325. Macroautophagy—friend or foe of viral replication?
  326. Influenza A virus infection‐induced macroautophagy facilitates MHC class II‐restricted endogenous presentation of an immunodominant viral epitope
  327. Endocrine and amino acid regulation of liver macroautophagy and proteolytic function
  328. Lipids in Mitochondrial Macroautophagy: Phase Behavior of Bilayers Containing Cardiolipin and Ceramide
  329. Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats
  330. Ubiquitin carboxyl-terminal hydrolase L1 of cardiomyocytes promotes macroautophagy and proteostasis and protects against post-myocardial infarction …
  331. One step closer to understanding mammalian macroautophagy initiation: Interplay of 2 HORMA architectures in the ULK1 complex
  332. Macroautophagy abnormality in essential tremor
  333. Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells
  334. Antigen processing for MHC presentation via macroautophagy
  335. Increased macroautophagy in interferon-gamma-producing T cells from patients with newly diagnosed systemic lupus erythematosus
  336. Defective macroautophagy in organelle turnover: From basic mechanisms to human disease
  337. Glycan degradation promotes macroautophagy
  338. Electron-microscopic evidence of mitochondriae containing macroautophagy in experimental acute pancreatitis: Implications for cell death
  339. Macroautophagy regulates nuclear NOTCH1 activity through multiple p62 binding sites
  340. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells
  341. Dynamics of macroautophagy: Modeling and oscillatory behavior
  342. Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells
  343. Effects of Macroautophagy and Mitophagy on the Pathogenicity of Fusarium graminearum
  344. Structural biology of the macroautophagy machinery
  345. Nuclear shelter: the influence of subcellular location on the processing of antigens by macroautophagy
  346. The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy
  347. The Roles of Monomeric GTP-Binding Proteins in Macroautophagy in Saccharomyces cerevisiae
  348. Small GTPase proteins in macroautophagy
  349. Ebb-and-flow of macroautophagy and chaperone-mediated autophagy in Raji cells induced by starvation and arsenic trioxide
  350. Localization and MHC class II presentation of antigens targeted for macroautophagy
  351. The mechanism of macroautophagy: The movie
  352. Selective macroautophagy for immunity
  353. Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins
  354. Analyzing macroautophagy in hepatocytes and the liver
  355. Artophagy: The art of autophagy—Macroautophagy
  356. Tributyltin activates the Keap1–Nrf2 pathway via a macroautophagy-independent reduction in Keap1
  357. Methods for functional analysis of macroautophagy in filamentous fungi
  358. … ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin–proteasome pathway and macroautophagy
  359. Macroautophagy is repressed during mitosis–seeing is believing
  360. HSc70 interactome reveal major role of macroautophagy and minor role of chaperone mediated autophagy in K-Ras G12V cell proliferation and survival
  361. Negative Modulation of Macroautophagy by Stabilized HERPUD1 is Counteracted by an Increased ER-Lysosomal Network With Impact in Drug-Induced …
  362. Amorphous areas in the cytoplasm of Dendrobium tepal cells: Production through organelle degradation and destruction through macroautophagy?
  363. Macromusophagy: A solo piano musical representation of macroautophagy
  364. Molecular mechanisms of macroautophagy, microautophagy, and chaperone-mediated autophagy
  365. Macroautophagy occurs in distal TMV-uninfected root tip tissue of tomato taking place systemic PCD
  366. Mechanism and dynamics of macroautophagy in murine exocrine pancreatic cells. A review of vinblastine-induced changes.
  367. Morbus Crohn—a disease of failing macroautophagy in the immune system?
  368. Degradation of mouse NTE-related esterase by macroautophagy and the proteasome
  369. Assays for monitoring macroautophagy activity in T cells
  370. Macroautophagy involved in testosterone synthesis in Leydig cells of male dairy goat (Capra hircus)
  371. mTOR suppresses macroautophagy during postnatal development of the striatum
  372. Vacuolar fragmentation promotes fluxes of microautophagy and micronucleophagy but not of macroautophagy
  373. Macroautophagy without LC3 conjugation?
  374. The N-acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy
  375. Rab5 modulates mutant huntingtin aggregation/toxicity in cell and fly models via macroautophagy
  376. The mechanism of macroautophagy: The movie
  377. Macroautophagy is involved in residual bodies formation during spermatogenesis in sea urchins, Strongylocentrotus intermedius
  378. The bidirectional roles of macroautophagy in the regulation of heart disease
  379. Macroautophagy and chaperone-mediated autophagy in aging
  380. Monitoring macroautophagy by major histocompatibility complex class II presentation of targeted antigens
  381. Septins are involved at the early stages of macroautophagy
  382. The G protein-Coupled Metabotropic Glutamate Receptor 1 controls neuronal macroautophagy
  383. Methods for monitoring macroautophagy
  384. At the Center of Macroautophagy: Autophagosomes
  385. Measuring macroautophagy in S. cerevisiae: autophagic body accumulation and total protein turnover
  386. The sequential switch from macroautophagy to chaperone-mediated autophagy in Raji cells induced by starvation
  387. Lipids in Mitochondrial Macroautophagy: Phase Behavior of Bilayers Containing Cardiolipin and Ceramide
  388. Macroautophagy regulates T helper cell activation and tolerance
  389. Myelin is remodeled cell-autonomously by oligodendroglial macroautophagy
  390. AR12 increases BAG3 expression via ER stress signaling which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy
  391. Defective macroautophagy in organelle turnover from basic mechanisms to human disease
  392. Macroautophagy as a target of cancer therapy
  393. The crosstalk between macroautophagy and Chaperone-Mediated Autophagy (CMA) is influenced by the lipid droplet-associated protein perilipin 2 (PLIN2) during …
  394. Macroautophagy triggered by sucrose starvation in higher plant cells: analysis of a model for prolonged carbon deprivation under water stress
  395. Methods for monitoring macroautophagy in pancreatic cancer cells
  396. Projection of an immunological self shadow to developing T cells via macroautophagy
  397. A conformational switch driven by phosphorylation regulates Ykt6 activity in macroautophagy
  398. Kinetics of macroautophagy in lung adenocarcinoma (A549) cells exposed to nanoparticles
  399. Brain macroautophagy on the ketogenic diet
  400. Monitoring antigen processing for MHC presentation via macroautophagy
  401. Regulation of Macroautophagy by Nutrients and Metabolites
  402. Ultrastructure of the Macroautophagy Pathway in Mammalian Cells
  403. Singlet oxygen-dependent chloroplast degradation is independent of macroautophagy in the Arabidopsis ferrochelatase two mutant
  404. Role of Macroautophagy in Anti‐Cancer Effects of the Novel Sphingolipid, Enigmol
  405. Human WIPIs as Phosphoinositide Effectors at the Nascent Autophagosome: A Robust Tool to Assess Macroautophagy by Quantitative Imaging
  406. Molecular mechanisms of macroautophagy, microautophagy, and chaperone-mediated autophagy
  407. Impaired mTOR Macroautophagy and Neurocognitive Deficits in Tuberous Sclerosis Complex
  408. AB254. DU145: a naturally occurring cell with ATG5-independent alternative macroautophagy
  409. Deciphering the impact of macroautophagy perturbation by influenza A virus on virus replication and host cell response to infection
  410. Systems biology approaches for neurodegeneration and macroautophagy
  411. Early Secretory Pathway Gene TRS85 is Required for Selective Macroautophagy of Peroxisomes in Yarrowia lipolytica
  412. A PCR analysis of the ubiquitin-like conjugation systems in macroautophagy
  413. A comparative map of macroautophagy and mitophagy in retinal cells
  414. A1. 23 Macroautophagy deficiency in dendritic cells exacerbates antigen-induced arthritis
  415. A2. 32 Macroautophagy proteins control dendritic cell activation and shape the TH1/TH17 response during antigen induced arthritis
  416. Dysregulated macroautophagy and abnormal mitochondria in Cystic Fibrosis
  417. P3-17-08: Macroautophagy Protects Breast Cancer MCF-7 Cells from TAM-Induced Apoptosis Via Mitogen-Activated Protein Kinase (MAPK) Pathway.
  418. Evaluation of anti-tumor effects of VER-155008, a functional inhibitor of HSP70, through macroautophagy in mesothelioma cells
  419. Mechanisms of autophagy: the machinery of macroautophagy and points of control
  420. Free Paper Presentation: OS-64; Macroautophagy Activation via Nrf2-Dependent Up-Regulation of LC3B Limits Proteasome Inhibitor (PI)-Induced Lung Cancer Cell …
  421. Aberrant macroautophagy and cleaved C3 production in MRL/lpr hippocampus
  422. Induction of macroautophagy by exogenously introduced calcium
  423. Macroautophagy overexpression leads to oxidized proteins accumulation after a short time of oxidative stress
  424. Chaperone mediated autophagy responds to macroautophagy inhibition in motor neuron diseases
  425. Regulation of Macroautophagy in Idiopathic Pulmonary Fibrosis
  426. Activation Of Macroautophagy In The Human Diaphragm During Mechanical Ventilation
  427. A Novel High-Sensitivity High-Throughput Screening Platform for Macroautophagy and
  428. Investigation of mTOR-independent regulation of macroautophagy
  429. Overexpression of Fyn inhibits macroautophagy while activating the mTORC1-IRE1a pathway leading to cell death
  430. Identifying a Rab Effector on the Macroautophagy Pathway
  431. Elucidating the function of WAC in macroautophagy through investigating the WAC-GM130 interaction
  432. Role of Human WIPIs in Macroautophagy
  433. Macroautophagy, alpha-synuclein and dopamine neurotransmission: implications for Parkinson’s disease
  434. A Role for PICALM in Macroautophagy and Cellular Cholesterol Homeostasis
  435. Macroautophagy and ERK phosphorylation
  436. Huntingtin As a Scaffold for Selective Macroautophagy (S56. 002)
  437. Methods to Image Macroautophagy in the Brain In Vivo
  438. Mediation of Vesicular Fusion by SNARE Proteins during Macroautophagy
  439. Influenza A Virus Infection Induces Macroautophagy and MHC Class II-Restricted Endogenous Antigen Presentation
  440. The role of the co-chaperone BAG3 in selective macroautophagy: implications for aging and disease
  441. The role of macroautophagy in senescent cells and aged tissue
  442. Signal Regulation of WIPI Protein Function in Macroautophagy
  443. Implication of lymphocytes macroautophagy in humoral immune response
  444. HSPB8 FORMS WITH BAG3 A CHAPERONE COMPLEX STIMULATING MACROAUTOPHAGY: POSSIBLE INVOLVEMENT OF SHSP IN PROTEIN QUALITY …
  445. Macroautophagy Modulates Synaptic Function in the Striatum
  446. Inhibition of LRRK2 kinase activity stimulates macroautophagy☆
  447. P3-030 NIEMANN-PICK DISEASE TYPE C2 PROTEIN (NPC2; HE1) IS A CSF BIOMARKER OF MACROAUTOPHAGY
  448. CROSS-TALK BETWEEN THE UBIQUITIN-PROTEASOME SYSTEM AND MACROAUTOPHAGY
  449. JNK and Macroautophagy Activation by Bortezomib Has a Pro-Survival Effect in
  450. Characterization of the mechanisms underlying alterations in macroautophagy and survival signalling in Huntington’s disease
  451. Structural and Signaling Elements Important for the Efficient Degradation of BHMT through Macroautophagy
  452. The Effects of GMS Immunity-Related GTPases on Guanylate-Binding Proteins, Protein Aggregate Formation, and Macroautophagy
  453. Regulation of macroautophagy by vitamin A/retinoids
  454. Lipid challenge negatively affects macroautophagy and results in reduced CD4+ T cell function
  455. The effects of a purified B-group soyasaponin fraction on the proliferation, cell cycle progression and induction of macroautophagy in HCT-15 human colon …
  456. Macroautophagy in Major Histocompatibility Complex (MHC) class I-restricted Antigen Presentation
  457. Establishing a Role for Macroautophagy in Synaptic Stucture and Function
  458. The role of hypoxia-induced macroautophagy in melanomagenesis
  459. Regulation of macroautophagy in amiodarone induced pulmonary fibrosis
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