ATGL

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  1. Of mice and men: The physiological role of adipose triglyceride lipase (ATGL)
  2. Hints on ATGL implications in cancer: beyond bioenergetic clues
  3. Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl)
  4. Recent advances on the role of ATGL in cancer
  5. Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein
  6. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
  7. ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells
  8. The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ
  9. ATGL promotes autophagy/lipophagy via SIRT1 to control hepatic lipid droplet catabolism
  10. FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes
  11. Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
  12. Cold-induced thermogenesis depends on ATGL-mediated lipolysis in cardiac muscle, but not brown adipose tissue
  13. ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
  14. Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation
  15. Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
  16. Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2
  17. ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling
  18. Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK
  19. AMPK phosphorylates desnutrin/ATGL and hormone-sensitive lipase to regulate lipolysis and fatty acid oxidation within adipose tissue
  20. Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway
  21. SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL
  22. Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
  23. Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL
  24. Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction
  25. Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction
  26. Impact of reduced ATGL-mediated adipocyte lipolysis on obesity-associated insulin resistance and inflammation in male mice
  27. Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes
  28. The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively
  29. LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)
  30. Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells
  31. Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues
  32. Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific
  33. Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G (0)/G (1) switch gene 2 (G0S2) protein and mRNA content in human …
  34. Effect of endurance training intensity (low, moderate and high) on the expression of skeletal muscle ATGL protein and serum levels of insulin and glucose in …
  35. … mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB-hydrolase …
  36. Lipid Droplet Protein LID-1 Mediates ATGL-1-Dependent Lipolysis during Fasting in Caenorhabditis elegans
  37. The ATGL Gene Is Associated With Free Fatty Acids, Triglycerides, and Type 2 Diabetes
  38. Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells
  39. Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity
  40. Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1
  41. PGC-1/spargel counteracts high-fat-diet-induced obesity and cardiac lipotoxicity downstream of TOR and brummer ATGL lipase
  42. Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins
  43. Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity
  44. A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice
  45. Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53
  46. 17β‐estradiol supplementation attenuates ovariectomy‐induced increases in ATGL signaling and reduced perilipin expression in visceral adipose tissue
  47. Fenofibrate lowers lipid accumulation in myotubes by modulating the PPARα/AMPK/FoxO1/ATGL pathway
  48. Developmental, hormonal, and nutritional regulation of porcine adipose triglyceride lipase (ATGL)
  49. The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly
  50. ATGL-mediated triglyceride turnover and the regulation of mitochondrial capacity in skeletal muscle
  51. Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation
  52. Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function
  53. The novel non‐steroidal MR antagonist finerenone improves metabolic parameters in high‐fat diet‐fed mice and activates brown adipose tissue via AMPK‐ATGL …
  54. Regulation of hepatic triacylglycerol metabolism by CGI-58 does not require ATGL co-activation
  55. Regulation of ATGL expression mediated by leptin in vitro in porcine adipocyte lipolysis
  56. Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation
  57. Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator–activated receptor γ (PPARγ) …
  58. Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes
  59. Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism
  60. Adipose triglyceride lipase (ATGL) expression is associated with adiposity and tumor stromal proliferation in patients with pancreatic ductal adenocarcinoma
  61. ATGL/CGI-58-dependent hydrolysis of a lipid storage pool in murine enterocytes
  62. PPARa‐ATGL pathway improves muscle mitochondrial metabolism: implication in aging
  63. Ubiquitin ligase COP1 controls hepatic fat metabolism by targeting ATGL for degradation
  64. Chronic TNFα and cAMP pre-treatment of human adipocytes alter HSL, ATGL and perilipin to regulate basal and stimulated lipolysis
  65. ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells [S]
  66. Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice
  67. ATGL-1 mediates the effect of dietary restriction and the insulin/IGF-1 signaling pathway on longevity in C. elegans
  68. The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative …
  69. Long non-coding RNA NEAT1 facilitates the growth, migration, and invasion of ovarian cancer cells via the let-7 g/MEST/ATGL axis
  70. Atgl deficiency induces podocyte apoptosis and leads to glomerular filtration barrier damage
  71. Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure
  72. PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
  73. Fat-reducing effects of dehydroepiandrosterone involve upregulation of ATGL and HSL expression, and stimulation of lipolysis in adipose tissue
  74. ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity
  75. Restoration of lipid homeostasis between TG and PE by the LXRα-ATGL/EPT1 axis ameliorates hepatosteatosis
  76. Coordination among lipid droplets, peroxisomes, and mitochondria regulates energy expenditure through the CIDE-ATGL-PPARα pathway in adipocytes
  77. Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy
  78. Cytokine-mediated STAT3 transcription supports ATGL/CGI-58-dependent adipocyte lipolysis in cancer cachexia
  79. ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
  80. The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy
  81. Burkholderia pseudomallei interferes with host lipid metabolism via NR1D2-mediated PNPLA2/ATGL suppression to block autophagy-dependent inhibition of …
  82. Molecular cloning, expression profiling of adipose triglyceride lipase (ATGL) and forkhead box O1 (FoxO1), and effects of dietary carbohydrate level on their …
  83. Triptolide enhances lipolysis of adipocytes by enhancing ATGL transcription via upregulation of p53
  84. ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes
  85. PNPLA3 (I148M) inhibits lipolysis by perilipin-5-dependent competition with ATGL
  86. Localized increases in CEPT1 and ATGL elevate plasmalogen phosphatidylcholines in HDLs contributing to atheroprotective lipid profiles in hyperglycemic …
  87. ERα regulates lipid metabolism in bone through ATGL and perilipin
  88. Distinct roles for α-β hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling
  89. ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome-PTEN-mTOR-autophagy …
  90. … salt promote the muscle triglyceride hydrolysis during dry-salting by inducing the phosphorylation of adipose tissue triglyceride lipase (ATGL) and hormone-sensitive …
  91. Resting skeletal muscle PNPLA2 (ATGL) and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences
  92. Comparative proteomics reveals abnormal binding of ATGL and dysferlin on lipid droplets from pressure overload-induced dysfunctional rat hearts
  93. Palmitate induces fat accumulation via repressing FoxO1-mediated ATGL-dependent lipolysis in HepG2 hepatocytes
  94. Inhibition of age-related cytokines production by ATGL: a mechanism linked to the anti-inflammatory effect of resveratrol
  95. Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis
  96. Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles
  97. Long noncoding RNA LTCONS_00091578 associated with adipose triglyceride lipase (ATGL) regulates hepatic lipolysis in rainbow trout
  98. Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue
  99. Oroxylin A regulates the turnover of lipid droplet via downregulating adipose triglyceride lipase (ATGL) in hepatic stellate cells
  100. Depletion of Rab32 decreases intracellular lipid accumulation and induces lipolysis through enhancing ATGL expression in hepatocytes
  101. BETi enhance ATGL expression and its lipase activity to exert their antitumoral effects in triple-negative breast cancer (TNBC) cells
  102. Residues of the minimal sequence of G0S2 collectively contribute to ATGL inhibition while C-and N-terminal extensions promote binding to ATGL
  103. Piromelatine decreases triglyceride accumulation in insulin resistant 3T3-L1 adipocytes: role of ATGL and HSL
  104. Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicited PNPLA3 competitive binding to ATGL
  105. Adipose triglyceride lipase (ATGL) clone, expression pattern, and regulation by different lipid sources and lipid levels in large yellow croaker (Pseudosciaena crocea …
  106. OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis
  107. 4E-BPs control fat storage by regulating the expression of Egr1 and ATGL
  108. … of salt on intramuscular neutral lipid hydrolysis during dry-salting process of porcine (biceps femoris) muscles by inducing phosphorylation of ATGL, HSL and their …
  109. Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism
  110. Regulation of G0/G1 switch gene 2 (G0S2) protein ubiquitination and stability by triglyceride accumulation and ATGL interaction
  111. Mild mitochondrial uncoupling induces HSL/ATGL‐independent lipolysis relying on a form of autophagy in 3T3‐L1 adipocytes
  112. ATGL promotes the proliferation of hepatocellular carcinoma cells via the p‐AKT signaling pathway
  113. Lipid droplet-associated hydrolase promotes lipid droplet fusion and enhances ATGL degradation and triglyceride accumulation
  114. Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells
  115. Metformin regulates hepatic lipid metabolism through activating AMP-activated protein kinase and inducing ATGL in laying hens
  116. Hedgehog signaling promotes lipolysis in adipose tissue through directly regulating Bmm/ATGL lipase
  117. ATGL and HSL are not coordinately regulated in response to fuel partitioning in fasted rats
  118. … of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian …
  119. Changes of hormone-sensitive lipase (HSL), adipose tissue triglyceride lipase (ATGL) and free fatty acids in subcutaneous adipose tissues throughout the ripening …
  120. Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
  121. Adipose triglyceride lipase (Atgl) mediates the antibiotic jinggangmycin-stimulated reproduction in the brown planthopper, Nilaparvata lugens Stål
  122. PEDF promotes nuclear degradation of ATGL through COP1
  123. Aerobic exercise promotes the expression of ATGL and attenuates inflammation to improve hepatic steatosis via lncRNA SRA
  124. Circular RNA cMras Suppresses the Progression of Lung Adenocarcinoma Through ABHD5/ATGL Axis Using NF-κB Signaling Pathway
  125. The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro
  126. PKA/ATGL signaling pathway is involved in ER stress-mediated lipolysis in adipocytes of grass carp (Ctenopharyngodon idella)
  127. Maternal Prenatal Folic Acid Supplementation Programs Offspring Lipid Metabolism by Aberrant DNA Methylation in Hepatic ATGL and Adipose LPL in Rats
  128. The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes
  129. cDNA cloning, characterization, and variation analysis of chicken adipose triglyceride lipase (ATGL) gene
  130. HSL and ATGL: The movers and shakers of muscle lipolysis
  131. N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage
  132. Associations of ATGL gene polymorphisms with chicken growth and fat traits
  133. Molecular cloning of adipose triglyceride lipase (ATGL) gene from blunt snout bream and its expression after LPS-induced TNF-α factor
  134. Genetic control of ATGL-mediated lipolysis modulates adipose triglyceride stores in leptin-deficient mice
  135. The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients …
  136. ATGL-mediated lipophagy balances cholesterol-induced inflammation in pathogen infected Apostichopus japonicus coelomocytes
  137. Camptothecin activates SIRT1 to promote lipid catabolism through AMPK/FoxO1/ATGL pathway in C2C12 myogenic cells
  138. Identification and characterization of adipose triglyceride lipase (ATGL) gene in birds
  139. Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes
  140. … (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene …
  141. Overexpression of ATGL impairs lipid droplet accumulation by accelerating lipolysis in goat mammary epithelial cells
  142. Effect of global ATGL knockout on murine fasting glucose kinetics
  143. Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)
  144. Effects of dietary corn peptide and exercise on hepatic ATGL and TNF-α in obese rats
  145. The crucial role of ATGL for energy supply of muscles 1
  146. cDNA cloning, expression and regulation analysis of goose adipose triglyceride lipase (ATGL) gene
  147. Rare ATGL haplotypes are associated with increased plasma triglyceride concentrations in the Greenland Inuit
  148. Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity
  149. Lipase tug of war: PNPLA3 sequesters ABHD5 from ATGL
  150. Cloning and tissue expression analysis of adipose triglyceride lipase gene (ATGL) of Xinong Saanen dairy goats.
  151. ATGL gene expression and the influence of n-3 HUFAs in grass carp (Ctenopharyngodon idellus).
  152. Lutein prevents the excessive fat deposition in liver and abdominal tissues by activating SIRT1 and up-regulating ATGL and HSL in high fat diet rats (FS06-01-19)
  153. Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58)
  154. ATGL deficiency-induced triglyceride deposit cardiomyovasculopathy requiring heart transplant: a 5-year follow-up
  155. Neonatal exposure of bisphenol A led to increased lipolysis of visceral adipose tissue in adult rats with DNA hypomethylation of Atgl being one of the possible …
  156. The critical role of BTRC in hepatic steatosis as an ATGL E3 ligase
  157. The effect of interval and continuous training on the content of perilipin 1, ATGL and CGI-58 in visceral adipose tissue of obese male rats
  158. ATGL is differentially required for adipocyte FABP4 secretion in vivo and ex vivo
  159. 1336-P: FoxO1-ATGL-Sirt1-FoxO1 Feed Forward Signaling Mediates Effects on Hepatic Gene Expression and Glucose Homeostasis in LIRKO Mice
  160. Role of Elevated Adipose Triglyceride Lipase (ATGL) in Lipid Droplet (LDs) Utilization to Promote Colon Cancer Growth Reinforced by Obesity
  161. Effects of Complanatus flavonoids on triglyceride, DGAT2 and ATGL of hepatic in hyperlipidemia rats.
  162. The Role of ATGL-1 in CeTOR Regulated Longevity in C. Elegans
  163. Silencing ATGL gene expression inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells
  164. Adipose Triglyceride Lipase (ATGL) Has a Role in Muscle Lipid Oxidation and Is Upregulated by Pioglitazone in Adipose Tissue of Humans.
  165. Association of dietary and plasma fatty acids with adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) gene expression in human adipose tissues
  166. Hepatic ATGL manipulation regulates lipid metabolism through altered autophagy
  167. Proteomic analysis of proteins regulate ATGL lipolytic activity in skeletal muscle
  168. Mechanism of ATGL mediated changes in hepatic energy metabolism: role of LFABP
  169. Hepatic Adipose Triglyceride Lipase (ATGL) regulates glucose tolerance but not hepatic insulin signaling
  170. The Correlation Analysis of CHGA and ATGL in Patients of Type 2 Diabetes Mellitus with Nonalcoholic Fatty Liver Disease
  171. Relationship between serum ATGL and inflammatory factors in patients with coronary heart disease
  172. ATGL‐catalyzed lipolysis regulates SIRT1 to control PGC‐1a/PPAR‐a signaling
  173. Cyclin D1 regulates adipose triglyceride lipase (ATGL) to influence hepatic lipid droplet metabolism and cell proliferation
  174. Development of small-molecule inhibitors targeting adipose triglyceride lipase (ATGL)
  175. ATGL Is Not Required for Oleate Protection from Lipotoxicity in NIH3T3 Cells
  176. 289 Cardiomyocyte-specific ATGL over-expression prevents doxorubicin-induced cardiac dysfunction in mice
  177. Regulation of ATGL-mediated lipolysis by FSP2/CIDEC in human adipocytes
  178. ATGL-1 and longevity in C. elegans
  179. Adipose triglyceride lipase (ATGL) deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice 2
  180. Datset for” Resting skeletal muscle ATGL and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences”
  181. Hepatic ATGL Mediates Fatty Acid Oxidation and PPAR-α Signaling Through an LFABP-Independent Mechanism
  182. Adipocyte-specific Pharmacological Inhibition of Adipose Triglyceride Lipase (ATGL) Ameliorates Cardiac Fibrosis in Heart Failure
  183. Construction and identification of porcine adipose triglyceride lipase (ATGL) siRNA expression vector.
  184. Two novel missense mutations in bovine ATGL gene and their association with economic traits in Qinchuan cattle
  185. Quantification of Glucose Turnover and Cori Cycling in ATGL-knockout Mice by [U- 13C6]Glucose Infusion and LC-MS/MS Analysis of Glucose 13C-Isotopomers
  186. GW26-e1079 Comparative Proteomics Reveals Abnormal Binding of ATGL and Dysferlin on Dysfunctional Cardiac Lipid Droplets
  187. The role of Desnutrin/ATGL in promoting a brown‐adipose‐phenotype and regulation via AMPK
  188. Effect of endurance training intensity [low, moderate and high] on the expression of skeletal muscle ATGL protein and serum levels of insulin and glucose in male …
  189. The phosphorylation of serine 492 of perilipin A facilitates ATGL-mediated lipolysis by CGI-58 independent mechanisms
  190. The impact of ATGL deficiency on DHA biosynthesis
  191. … in Nutrition. The abstract “Lutein Prevents the Excessive Fat Deposition in Liver and Abdominal Tissues by Activating SIRT1 and Up-regulating ATGL and HSL in High …
  192. Adipose TriGlyceride Lipase (ATGL) and Hormone-Sensitive Lipase (HSL) protein expression is decreased in the obese insulin resistant state
  193. G0S2 impairs ATGL activity and cell cycle progression in murine liver
  194. AMPK Regulates Lipolysis by Phosphorylation of Desnutrin/ATGL at Serine406

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