DISEASE & DISORDERS

Glutamate: a neurotransmitter in mammalian brain Metabolism and role of Glutamate in mammalian brain Glutamate and the pathophysiology of hypoxic–ischemic brain damage Molecular diversity of Glutamate receptors and implications for brain function Metabotropic Glutamate receptors in brain function and pathology Cloning and expression of a rat brain L-Glutamate transporter Cellular localization of a metabotropic Glutamate […]

brain polyamine levels are altered in Alzheimer’s disease polyamine transport, accumulation, and release in brain The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain polyamine catabolism is enhanced after traumatic brain injury polyamine metabolism in different pathological states of the brain Overview

A Calcineurin/Akap Complex Is Required For Nmda Receptor–Dependent Long-Term Depression A Computational Study On The Role Of Glutamate And Nmda Receptors On Cortical Spreading depression Using A Multidomain Electrodiffusion Model A High-Dose Of Fentanyl Induced Delayed Anxiety-Like Behavior In Rats. Prevention By A Nmda Receptor Antagonist And Nitrous Oxide (N2O) A Neurotrophic Hypothesis Of Depression:

insulin & aging Reduced Circulating Insulin Enhances Insulin Sensitivity and Extends Lifespan The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. Genetic downregulation of insulin/insulin-like growth factor 1 (Igf1) signaling components can extend invertebrate and mammalian lifespan, but insulin resistance, a natural form of decreased insulin signaling, is associated with

mTor‐dependent stimulation of the association of eIF4G and eIF3 by insulin insulin signalling to mTor mediated by the Akt/PKB substrate PRAS40 The role of mammalian target of rapamycin (mTor) in insulin signaling Amino acid and insulin signaling via the mTor/p70 S6 kinase pathway: a negative feedback mechanism leading to insulin resistance in skeletal muscle cells

Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator Inflammatory cytokines IL-1α, IL-1β, IL-6, and TNF-α impart neuroprotection to an excitotoxin through distinct pathways Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure … dissociations

27 Viral Infections And Adiposity A Blood Glucose Level Between 72 Mg/Dl (4 Mmol/L) And 108 Mg/Dl (6 Mmol/L) Is Considered Normal For A Healthy Adult. A Deeper Look Into Adenovirus-36 And Obesity A Framework For Identification Of Infections That Contribute To Human Obesity A Microbiological Explanation For The Obesity Pandemic? A Polymerase Chain Reaction

Molecular regulation of adipogenesis Transcriptional regulation of adipogenesis Regulating adipogenesis New developments in adipogenesis Inhibition of adipogenesis by Wnt signaling Regulation of Wnt signaling during adipogenesis Angiogenesis modulates adipogenesis and obesity C/EBPα induces adipogenesis through PPARγ: a unified pathway adipogenesis and WNT signalling adipogenesis and obesity: rounding out the big picture Transcriptional control of adipogenesis

… -(5-methylpyridin-2-yl)− 1H-pyrazol-5-yl) pyrazolo [1, 5-a] pyrimidine-3-carboxamide as a new potential PET agent for imaging of IRAK4 enzyme in neuroinflammation … -1 gp120 and Methamphetamine-mediated Induction of Proinflammatory Cytokines/chemokines and Oxidative Stress in Astrocytes: Implications in neuroinflammation … -19 MRI at 21.1 T: enhanced spin–lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo

  A Role For Somatostatin In The Impaired insulin Secretory Response To glucose By Islets From Aging Rats A Study Of The Effect Of Aging On insulin And Glueagon Release During Intravenous glucose Tolerance Test Ability Of insulin To Modulate Hepatic glucose Production In Aging Rats Is Impaired By Fat Accumulation Accumulation Of Advanced glycation