SCIENCE

PPARY2

2-Methylene-19-Nor-1Α-Hydroxyvitamin D3 Analogs Inhibit Adipocyte Differentiation And Pparγ2 Gene Transcription A 45 Kda Protein Related To Pparγ2, Induced By Peroxisome Proliferators, Is Located In The Mitochondrial Matrix A Effect Of Pparγ2 Genetic Polymorphism On Dietary Intervention In Hyperglycemia People. A Novel 3T3-L1 Preadipocyte Variant That Expresses Pparγ2 And Rxrα But Does Not Undergo Differentiation A […]

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PHYTOECDYSTEROIDS

PhytoecdysteroidS Phytoecdysteroids are plant-derived ecdysteroids. Phytoecdysteroids are a class of chemicals that plants synthesize for defense against phytophagous (plant eating) insects. These compounds are mimics of hormones used by arthropods in the molting process known as ecdysis. When insects eat the plants with these chemicals they may prematurely molt, lose weight, or suffer other metabolic

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MYOSTATIN INHIBITION AND MUSCLE GROWTH

… , Autophagy and Cell Death: G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle … … a spinal muscular atrophy (SMA) discordant family identifies a novel mutation in TLL2, an activator of growth differentiation factor 8 (myostatin): a case report … activity of follistatin isoforms and follistatin-like-3 is dependent

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MYOSTATIN INHIBITION PRESERVES MUSCLE

… , Autophagy and Cell Death: G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle … … cycle regulation of protein synthesis in skeletal muscle of the blackback land crab, Gecarcinus lateralis, and the differential expression of a myostatin-like factor during … … Deprivation Regimen Preserves Protein Metabolism During Fasting

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ANTI COVID-19 EFFECTS OF MEDICINAL PLANTS, FLAVONOIDS & POLYPHENOLS

… IN THE COVID-19 PANDEMIC WITH THE FAMILY-CENTERED NURSING APPROACH AND THE UTILIZATION OF FAMILY MEDICINAL PLANTS: A … … of potent inhibitors of COVID-19 main protease (Mpro) and angiotensin converting enzyme 2 (ACE2) from natural products: Quercetin, hispidulin, and … … search for potential COVID-19 drugs from FDA-approved drugs and small molecules of natural

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INSULIN & AGING

insulin & aging Reduced Circulating Insulin Enhances Insulin Sensitivity and Extends Lifespan The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. Genetic downregulation of insulin/insulin-like growth factor 1 (Igf1) signaling components can extend invertebrate and mammalian lifespan, but insulin resistance, a natural form of decreased insulin signaling, is associated with

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INSULIN & MTOR

mTor‐dependent stimulation of the association of eIF4G and eIF3 by insulin insulin signalling to mTor mediated by the Akt/PKB substrate PRAS40 The role of mammalian target of rapamycin (mTor) in insulin signaling Amino acid and insulin signaling via the mTor/p70 S6 kinase pathway: a negative feedback mechanism leading to insulin resistance in skeletal muscle cells

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EXCITOXICITY & THE BRAIN

Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator Inflammatory cytokines IL-1α, IL-1β, IL-6, and TNF-α impart neuroprotection to an excitotoxin through distinct pathways Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure … dissociations

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NOOTROPICS

SCIENTIFIC STUDIES 2-Methyl-3-Phenylaminomethylquinolin-4-One As Potential Antidepressant With Nootropic Properties A Brief Introduction Of Docosahexaenoic Acid And Its Nootropic Effect [J] A Carbon-13 Nmr Spin-Lattice Relaxation Study Of The Molecular Conformation Of The Nootropic Drug 2-Oxopyrrolidin-1-Ylacetamide A Clinical And Neurophysiological Trial On Nootropic Drugs In Patients With Mental Decline. A Combination Of Nootropic Ingredients (Caf+) Is

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ANTI-ACNE EFFECT OF FLAVONOIDS & POLYPHENOLS

Recent evidence underlines the role of Western diet in the pathogenesis of acne.   💥Acne is absent in populations consuming Palaeolithic diets with low glycaemic load and no consumption of milk or dairy products. Two randomized controlled studies, one of which is presented in this issue of Acta Dermato-Venereologica, have provided evidence for the beneficial

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