Evading apoptosis in cancer Carcinogenesis is a mechanistically complex and variable process with a plethora of underlying genetic causes. Cancer development consists of a multitude of steps that occur progressively starting with initial driver mutation(s), to tumorigenesis, and ultimately metastasis. During these transitions, cancer cells accumulate a series of genetic alterations that confer upon the […]
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Epigenetic Modifiers Exacerbate Oxidative Stress In Renal Proximal Tubule Cells Epigenetic Modifiers As Anticancer Drugs: Effectiveness Of Valproic Acid In Neural Crest-Derived Tumor Cells Epigenetic Modifiers Exert Renal Toxicity Through Induction Of P66Shc Combining Oncolytic Viruses With Epigenetic Modifiers To Treat Acute Lymphocytic Leukemias The Role Of Epigenetic Modifiers In Hematopoiesis A Screen For Modifiers
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1, 25-Dihydroxyvitamin D3 Treatment Delays Cellular Aging In Human Mesenchymal Stem Cells While Maintaining Their Multipotent Capacity 14Th Napreca Symposium And Aamps Ethnoveterinary Medicine… 1-Deoxynojirimycin Attenuates High Glucose-Accelerated Senescence In Human Umbilical Vein Endothelial Cells 24: Cerebral White Matter Lesions In Formerly (Pre)-Eclamptic Women A Deficit In Collagenase Activity Contributes To Impaired Migration Of Aged
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140-3D Hydrogels and Bioinks for Realistic In Vitro Modelling and Bioprinting A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4 Advances in Senotherapies Ageing: Targeting senescence-associated tissue damage Ageing: Tools to eliminate senescent cells Aging and Senotherapeutics Autophagy Dysfunction, Cellular Senescence, and Abnormal Immune-Inflammatory
A Role For Somatostatin In The Impaired insulin Secretory Response To glucose By Islets From Aging Rats A Study Of The Effect Of Aging On insulin And Glueagon Release During Intravenous glucose Tolerance Test Ability Of insulin To Modulate Hepatic glucose Production In Aging Rats Is Impaired By Fat Accumulation Accumulation Of Advanced glycation
A 4-Week Repeated Oral Dose Toxicity Study Of Fucoidan From The Sporophyll Of Undaria Pinnatifida In Sprague–Dawley Rats A Case Of Symptomatic Inflammatory Tongue Treated With Fucoidan A Comparative Study Of Antithrombotic Activities Of Fucoidan With Different Molecular Weight And Its Mechanism A Comparison Of Fucoidan Conjugated To Paclitaxel And Curcumin For The Dual Delivery
“Photoaging is the term used to describe the clinical, histologic, and functional changes in chronically sun-exposed skin of middle-aged and elderly adults. The importance of photoaging lies in its cosmetic and hence psychosocial impact on a large percentage of older adults, its intimate but incompletely understood relationship to skin cancer, as well as various functional
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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells,
The release of cytokines is central to almost every stage of the immune response to allergens… how do you turn down the cytokines and stop the body from having an allergic reaction? Flavonoids and Polyphenols! … -[Beta] c Receptor Antibody Targets Multiple Effector Cell Populations In Human Nasal Polyps Transplanted Into Immunodeficient Transgenic Human Interleukin-3 (il-3
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A Combination Of Remote Ischemic Perconditioning And Cerebral Ischemic Postconditioning Inhibits Autophagy To Attenuate Plasma Hmgb1 And Induce Neuroprotection … A Comparison Of Hmgb1 Concentrations Between Cerebrospinal Fluid And Blood In Patients With Neurological Disease A Critical Cysteine Is Required For Hmgb1 Binding To Toll-Like Receptor 4 And Activation Of Macrophage Cytokine Release A Critical
