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- Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic β-cells against oxidative stress
- Dihydroavenanthramide D protects pancreatic β-cells from cytokine and streptozotocin toxicity
- … expression and nuclear factor-κB-dependent apoptosis in pancreatic β-cells: potential mechanisms for viral-induced insulitis and β-cell death in type 1 diabetes …
- Autoimmune destruction of pancreatic β cells
- Suppressor of cytokine signaling-1 overexpression protects pancreatic β cells from CD8+ T cell-mediated autoimmune destruction
- Suppression of SOCS3 expression in the pancreatic β-cell leads to resistance to type 1 diabetes
- Silymarin Protects pancreatic β-cells against Cytokine-Mediated Toxicity: Implication of c-Jun NH2-Terminal Kinase and Janus Kinase/Signal Transducer and …
- Pronounced cytosolic aggregation of cellular prion protein in pancreatic β-cells in response to hyperglycemia
- Cytokine-induced inhibition of insulin release from mouse pancreatic β-cells deficient in inducible nitric oxide synthase
- Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-γ-induced apoptosis in primary pancreatic β-cells
- Tissue inhibitor of metalloproteinase-2 inhibits T-cell infiltration and preserves pancreatic β-cell function in an in vitro type 1 diabetes mellitus model
- Urocortin III is expressed in pancreatic β-cells and stimulates insulin and glucagon secretion
- Specific expression of Bax-ω in pancreatic β-cells is down-regulated by cytokines before the onset of apoptosis
- Fulminant type 1 diabetes: a novel clinical entity requiring special attention by all medical practitioners
- Potential role of NO in modulation of COX-2 expression and PGE2 production in pancreatic β-cells
- Spontaneous regeneration of pancreatic β-cells in EMC-D virus-induced diabetic mice and reversion from diabetic to normal state
- Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic β cells develop insulin-dependent diabetes without insulitis
- The a3 isoform of V-ATPase regulates insulin secretion from pancreatic β-cells
- Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
- T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
- Melatonin protects against streptozotocin, but not interleukin‐1β‐induced damage of rodent pancreatic β‐cells
- Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells
- Mouse models for type 1 diabetes
- Partial preservation of pancreatic β-cells by vanadian: Evidence for long-term amelioration of diabetes
- Fulminant type 1 diabetes in Caucasians: a report of three cases
- NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic β cells
- β-cell proliferation is the major source of new pancreatic β cells
- Leaking gut in type 1 diabetes
- IFNβ accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to β cells in nondiabetes-prone mice
- Direct effects of cyclosporin A on human pancreatic β-cells
- Beneficial effect of Flos magnoliae extract on multiple low dose streptozotocin-induced type 1 diabetes development and cytokine-induced β-cell damage
- Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic β-cells and the involvement of neuroligin in insulin secretion
- Protective effect of retinoic acid on interleukin-1β-induced cytotoxicity of pancreatic β-cells
- Significance of serum CXCL10/IP-10 level in type 1 diabetes
- Interferon-α and interferon-γ differentially affect pancreatic β-cell phenotype and function
- Increased expression of GAD65 and GABA in pancreatic β-cells impairs first-phase insulin secretion
- Notch signaling: a mediator of β-cell de-differentiation in diabetes?
- Tumor necrosis factor-related apoptosis-inducing ligand and CD56 expression in patients with type 1 diabetes mellitus
- Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic β cells by Bcl-2 and X-linked inhibitor of …
- Bacteria of food and human intestine are the most possible sources of the gad-trigger of type 1 diabetes
- Production and Characterization of Reg Knockout Mice: Reduced Proliferation of pancreatic β-cells in Reg Knockout Mice
- Nitric oxide stimulates insulin gene transcription in pancreatic β-cells
- T-splenocytes from non-obese diabetic mice binding to xenogeneic pancreatic β-cells in vitro: implication of the α/β T-cell receptor and of major histocompatibility …
- Calmodulin overexpression causes Ca2+-dependent apoptosis of pancreatic β cells, which can be prevented by inhibition of nitric oxide synthase
- Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population: clinical investigation
- Toll-like Receptor 2 and Type 1 diabetes
- Peptide-specific cytotoxicity of T lymphocytes against glutamic acid decarboxylase and insulin in type 1 diabetes mellitus
- A common stromal cell–derived factor-1 chemokine gene variant is associated with the early onset of type 1 diabetes
- Viral trigger for diabetes?
- Dissociation between Fas expression and induction of apoptosis in human islets of Langerhans
- Repression of GAD autoantigen expression in pancreas β-cells by delivery of antisense plasmid/PEG-g-PLL complex
- Beneficial effect of supplementation with copper sulfate on STZ-diabetic mice (IDDM)
- Prostaglandins inhibit pancreatic β-cell replication and long-term insulin secretion by pertussis toxin-insensitive mechanisms but do not mediate the actions of …
- Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease?
- Physiological β cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
- SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes
- Oxidative stress in type 1 diabetes
- HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example
- CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-β–TGF-β receptor interactions in type 1 diabetes
- Target cell defense prevents the development of diabetes after viral infection
- Methylmercury induces pancreatic β-cell apoptosis and dysfunction
- CD8+ T-cells and their interaction with other cells in damage to islet β-cells
- Guggulsterone, a plant sterol, inhibits NF-κB activation and protects pancreatic β cells from cytokine toxicity
- Natural killer cells are required for accelerated type 1 diabetes driven by interferon-β
- Among CXCR3 chemokines, IFN-γ-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-γ (CXCL9) imprints a pattern for …
- Down regulation of NF-kappa B as a therapeutic strategy for type 1 diabetes: effect of flavonoids
- pancreatic Β-cell protective effect of rutin and apigenin isolated from Teucrium polium
- A virus–gene collaboration
- Inhibitory effects of epicatechin on interleukin-1β-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of …
- Enteroviral capsid protein detected in pancreatic islets
- Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells
- Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats
- NIT-1, a pancreatic β-cell line established from a transgenic NOD/Lt mouse
- Coxsackievirus infection as an environmental factor in the etiology of type 1 diabetes
- Anti-diabetic activity of fruits of Terminalia chebula on streptozotocin induced diabetic rats
- Cytokine profile in children during the first 3 months after the diagnosis of type 1 diabetes
- Biochemical and molecular actions of interleukin-1 on pancreatic β-cells
- Facilitative glucose transporter 9 expression affects glucose sensing in pancreatic β-cells
- Islet proteins implicated in pathogenesis of type 1 diabetes mellitus
- Immunological aspects of ‘fulminant type 1 diabetes‘
- Constitutive expression of placental lactogen in pancreatic β cells: effects on cell morphology, growth, and gene expression
- Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients
- Putative environmental factors in type 1 diabetes
- Association between type 1 diabetes age-at-onset and intercellular adhesion molecule-1 (ICAM-1) gene polymorphism
- Increased Susceptibility to Streptozotocin-Induced β-Cell Apoptosis and Delayed Autoimmune diabetes in Alkylpurine- DNA-N-Glycosylase-Deficient Mice
- Type 1 diabetes mellitus associated with clinical acute pancreatitis in an adult
- How viral infections affect the autoimmune process leading to type 1 diabetes
- Molecular target structures in alloxan-induced diabetes in mice
- Neuronal elements in the pathogenesis of type 1 diabetes
- A Low Voltage-Activated Ca2+ Current Mediates Cytokine-Induced pancreatic β-Cell Death
- Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice
- Evidence from transgenic mice that interferon-β may be involved in the onset of diabetes mellitus
- Insulin in oral immune “tolerance”: a one-amino acid change in the B chain makes the difference
- IL-2 and its high-affinity receptor: genetic control of immunoregulation and autoimmunity
- The metabolic basis of insulin secretion
- Autoimmune diabetes in HLA‐DR3/DQ8 transgenic mice expressing the co‐stimulatory molecule B7‐1 in the β cells of islets of Langerhans
- Vitamin D target proteins: function and regulation
- A case of fulminant type 1 diabetes with coxsackie B4 virus infection diagnosed by elevated serum levels of neutralizing antibody
- Double-stranded ribonucleic acid (RNA) induces β-cell Fas messenger RNA expression and increases cytokine-induced β-cell apoptosis
- Autoimmune islet destruction in spontaneous type 1 diabetes is not β-cell exclusive
- Understanding autoimmune diabetes: insights from mouse models
- STAT4: a risk factor for type 1 diabetes?
- DESIGN AND SYNTHESIS OF DNA MINOR GROOVE METHYLATING COMPOUNDS THAT TARGET pancreatic β-cells
- Enteroviruses: new findings on the role of enteroviruses in type 1 diabetes
- T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event
- Pregnancy-induced rise in serum C-peptide concentrations in women with type 1 diabetes
- Innate immunity and intestinal microbiota in the development of Type 1 diabetes
- Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis
- TGFβ plasmid construction and delivery for the prevention of type 1 diabetes
- The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFκB activation
- Cytokines and their roles in pancreatic islet β-cell destruction and insulin-dependent diabetes mellitus
- In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis
- RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection
- Dietary microbial toxins and type 1 diabetes
- Islet regeneration needed for overcoming autoimmune destruction–considerations on the pathogenesis of type 1 diabetes
- Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in β cells
- Sulforaphane protects against cytokine-and streptozotocin-induced β-cell damage by suppressing the NF-κB pathway
- Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32. 3 producing susceptibility to type 1 diabetes
- The ABBOS-peptide from bovine serum albumin causes an IFN-γ and IL-4 mRNA response in lymphocytes from children with recent onset of type 1 diabetes
- Is innervation an early target in autoimmune diabetes?
- Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL
- Remission of the newly diagnosed type 1 diabetes by radiation of the pancreas
- Vesicular autoantigens of type 1 diabetes
- Aire Deficiency Causes Increased Susceptibility to Streptozotocin‐induced Murine Type 1 diabetes
- Review series on helminths, immune modulation and the hygiene hypothesis: how might infection modulate the onset of type 1 diabetes?
- Murder mysteries in type 1 diabetes
- Supplementation of N‐acetylcysteine inhibits NFκB activation and protects against alloxan‐induced diabetes in CD‐1 mice
- Making insulin-deficient type 1 diabetic rodents thrive without insulin
- Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
- In situ β cell death promotes priming of diabetogenic CD8 T lymphocytes
- Novel epitope begets a novel pathway in type 1 diabetes progression
- A dual role for TNF-α in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis
- Pituitary adenylate cyclase-activating polypeptide prevents cytokine-induced cytotoxicity via inhibition of inducible nitric oxide synthase expression in βTC cells
- The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self‐antigen‐specific immunoglobulin receptors
- Thymic expression of insulin‐related genes in an animal model of autoimmune type 1 diabetes
- Expression of Calbindin-D28k in a pancreatic Isletβ -Cell Line Protects against Cytokine-Induced Apoptosis and Necrosis
- Intracellular Ca2+ Modulation of ATP-Sensitive K+ Channel Activity in Acetylcholine-Induced Activation of Rat pancreatic β-cells
- Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes
- GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule
- Ontogeny of regeneration of β-cells in the neonatal rat after treatment with streptozotocin
- Stimulation of insulin release by glucose is associated with an increase in the number of docked granules in the β-cells of rat pancreatic islets
- Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer
- Expression of cholera toxin B–proinsulin fusion protein in lettuce and tobacco chloroplasts–oral administration protects against development of insulitis in non‐obese …
- Role of gelatinase B in diabetes and long-term complications of hyperglycaemia
- Come and get me!
- Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1
- The molecular genetics of type 1 diabetes: new genes and emerging mechanisms
- Tomographic molecular imaging and 3D quantification within adult mouse organs
- Effect of Eugenia jambolana seed kernel on antioxidant defense system in streptozotocin-induced diabetes in rats
- CBLB variants in type 1 diabetes and their genetic interaction with CTLA4
- Transgenic animal models for type 1 diabetes: linking a tetracycline-inducible promoter with a virus-inducible mouse model
- Polymorphisms of CXCR3-binding chemokines in type 1 diabetes
- Endothelin inhibition delays onset of hyperglycemia and associated vascular injury in type I diabetes: Evidence for endothelin release by pancreatic islet β-cells
- Analysis of eluted peptides from type 1 diabetes-susceptible HLA class II molecules identified novel islet protein, heparin/heparan sulfate-interacting protein
- Severe hyperglycaemia caused by autoimmunization to β cells in rats
- Antioxidant and protective effects of major flavonoids from Teucrium polium on β-cell destruction in a model of streptozotocin-induced diabetes
- Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin‐induced diabetic rats fed with Momordica charantia fruit extract
- Transient but not permanent neonatal diabetes mellitus is associated with paternal uniparental isodisomy of chromosome 6
- Recent advances in the immunogenetics of human type 1 diabetes
- Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice
- High-level expression of interleukin-4 following electroporation-mediated gene transfer accelerates type 1 diabetes in NOD mice
- Autoantibodies in recent onset type-1 diabetic patients to a Mr 60K microsomal hepatic protein: new evidence for autoantibodies to the type-2 glucose transporter
- INTERLEUKIN 1βINCREASES ARGININE ACCUMULATION AND ACTIVATES THE CITRULLINE–NO CYCLE IN RAT pancreaticβCELLS
- Enteropathy precedes type 1 diabetes in the BB rat
- Interferon-γ independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic β-cell lines
- Normal T cell development in the absence of thymic insulin expression
- The perks of balancing glucose
- Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes
- Identification of a novel type 1 diabetes susceptibility gene, T-bet
- Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice
- TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats
- Antidiabetic and ameliorative potential of Ficus bengalensis bark extract in streptozotocin induced diabetic rats
- CD11a expression and soluble ICAM-1 levels in peripheral blood in high-risk and overt type 1 diabetes subjects
- Autoantibodies and CD4 T cells target a β cell retroviral envelope protein in non‐obese diabetic mice
- Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into β-cells
- Evidence for recognition of novel islet T cell antigens by granule-specific T cell lines from new onset type 1 diabetic patients
- Modeling the onset of type 1 diabetes
- Infection and autoimmunity: are we winning the war, only to lose the peace?
- Effect of Intraperitoneal Needling on pancreatic β-Cell Cytotoxicity Mediated via Alloxan in Mice with an FVB/N Genetic Background
- Metabolism genes are among the differentially expressed ones observed in lymphomononuclear cells of recently diagnosed type 1 diabetes mellitus patients
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- The genetics of canine diabetes: a candidate gene study
- Increased islet antigen presentation leads to type‐1 diabetes in mice with autoimmune susceptibility
- Interleukin-1β activates a short STAT-3 isoform in clonal insulin-secreting cells
- Helminth infection can reduce insulitis and type 1 diabetes through CD25-and IL-10-independent mechanisms
- Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel β cell autoantigen in type 1 diabetes
- Vitamin D in type 1 diabetes prevention
- Downregulation of apoptosis in the target tissue prevents low-dose streptozotocin-induced autoimmune diabetes
- Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes
- A key role for ICAM-1 in generating effector cells mediating inflammatory responses
- Cellular distribution and contribution of cyclooxygenase (COX)-2 to diabetogenesis in NOD mouse
- Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK
- Effects of tyrosine kinase inhibitors on cell death induced by sodium fluoride and pertussis toxin in the pancreatic β‐cell line, RINm5F
- Effect of Undaria pinnatifida Extract on Insulin Secretion from the Pancreas of Diabetic Rats
- Insulitis in type 1 diabetes: a sticky problem
- Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes
- Transplacental exposure to bafilomycin disrupts pancreatic islet organogenesis and accelerates diabetes onset in NOD mice
- β cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice
- MafA differentiates rat intestinal cells into insulin-producing cells
- Selective autoantibody production against CCL3 is associated with human type 1 diabetes mellitus and serves as a novel biomarker for its diagnosis
- Glucose regulated protein synthesis in pancreatic β-cells
- The Effect of Parental Imprinting on the INS-IGF2 Locus of Korean Type I Diabetic Patients
- Antibodies against different epitopes of heat-shock protein 60 in children with type 1 diabetes mellitus
- Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells
- Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants
- Characterization of the anti-tissue transglutaminase antibody response in nonobese diabetic mice
- The possible role of autoimmunity in the pathogenesis of diabetes in beta-thalassemia major
- MIN6 β-cell–β-cell interactions influence insulin secretory responses to nutrients and non-nutrients
- NKT cells and IFN-γ establish the regulatory environment for the control of diabetogenic T cells in the nonobese diabetic mouse
- Trace element changes in the pancreas during viral infection in mice
- The specific p38 mitogen-activated protein kinase pathway inhibitor FR167653 keeps insulitis benign in nonobese diabetic mice
- Protective effects of epicatechin against the toxic effects of streptozotocin on rat pancreatic islets: in vivo and in vitro
- A new look at viruses in type 1 diabetes
- Cryptic infection and autoimmunity
- Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet β-cells
- Biophysical evidence that connexin-36 forms functional gap junction channels between pancreatic mouse β-cells
- Genetic association between interleukin-10 gene promoter region polymorphisms and type 1 diabetes age-at-onset
- pancreatic lymph node-derived CD4+ CD25+ Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals
- Fas/Fas ligand interactions play an essential role in the initiation of murine autoimmune diabetes
- Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII
- Clearance of apoptotic β-cells is reduced in neonatal autoimmune diabetes-prone rats
- Zurina Hassan*, Mariam Ahmad A. Pauzi M. Yusof, S. Raghava Naidu1
- An early but intense cytokine production within the islets may be predictive for type 1 diabetes occurrence in the Bio Breeding (BB) rat
- A biphasic role of nuclear transcription factor (NF)‐κB in the islet β‐cell apoptosis induced by interleukin (IL)‐1β
- Administration of NF‐κB decoy inhibits pancreatic activation of NF‐κB and prevents diabetogenesis by alloxan in mice
- Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet β cells
- SUMO wrestling with type 1 diabetes
- Mechanism of exocrine pancreatic insufficiency in streptozotocin‐induced type 1 diabetes mellitus
- Postprandial hyperinsulinaemic hypoglycaemia and type 1 diabetes mellitus
- Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes
- Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes
- Genetics and molecular biology: HDLs and their multiple ways to protect cells
- Intron polymorphism in the KIAA0350 gene is reproducibly associated with susceptibility to type 1 diabetes (T1D) in the Han Chinese population
- Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families
- Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice
- Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response
- Genetic and phenotypic diversity of echovirus 30 strains and pathogenesis of type 1 diabetes
- Peripherin is a relevant neuroendocrine autoantigen recognized by islet-infiltrating B lymphocytes
- Fas ligand down-regulates cytokine-induced Fas receptor expression on insulinoma (NIT-1), but not islet cells, from autoimmune nonobese diabetic mice
- Effect of fusidic acid on interleukin-1 (IL-1)-and IL-6-induced pancreatic β-cell functions in rats
- Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts
- Altered phenotype and function of dendritic cells in children with type 1 diabetes
- Mucosal exposure to antigen: cause or cure of type 1 diabetes?
- Congenic mapping of type 1 diabetes—protective gene (s) in an interval of 4 Mb on rat chromosome 6q32
- Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models
- Putting the pieces of the puzzle together–a series of hypotheses on the etiology and pathogenesis of type 1 diabetes
- Intestinal microbiota gives a nod to the hygiene hypothesis in type 1 diabetes
- Development of autoreactive diabetogenic T cells in the thymus of NOD mice
- Interactions between programmed death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) gene polymorphisms in type 1 diabetes
- No Evidence for Linkage in Swedish Multiplex T1DM Families to IL12B on Chromosome 5q33‐34
- A novel mutation of WFS1 gene in a Japanese man of Wolfram syndrome with positive diabetes-related antibodies
- An altered self-peptide with superagonist activity blocks a CD8-mediated mouse model of type 1 diabetes
- Screening for associated autoimmunity in children and adolescents with type 1 diabetes mellitus (T1DM)
- Type 1 diabetes in the BB rat: a polygenic disease
- A critical role of STAT1 in streptozotocin-induced diabetic liver injury in mice: controlled by ATF3
- A review of the use of Streptozotocin (STZ) in the induction of diabetes in rats and subsequent ocular tissue changes
- Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes
- Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4
- Enterovirus RNA is found in peripheral blood mononuclear cells in a majority of type 1 diabetic children at onset
- High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas
- Environmental risk factors for type 1 diabetes in Rome and province
- Protective effects of combined micronutrients on islet β-cells of streptozotocin-induced diabetic mice
- Characterization of two porcine proinsulin reactive monoclonal antibodies by immunostaining of β-cells in pancreatic sections of different species
- Type 1 diabetes mellitus and multiple sclerosis: common etiological features
- Simultaneous type 1 diabetes onset in mother and son coincident with an enteroviral infection
- Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus
- Coxsackie virus B antibodies are increased in HLA DR3-MICA5. 1 positive type 1 diabetes patients in the Linköping region of Sweden
- Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study
- Immunology in diabetes: an update
- Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFκB activation offering protection against chemically induced diabetes
- A type 1 diabetes-related protein from wheat (Triticum aestivum): cDNA clone of a wheat storage globulin, Glb1, linked to islet damage
- CTLA4 gene polymorphism correlates with the mode of onset and presence of ICA512 Ab in Japanese type 1 diabetes
- Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide
- Possible role of gangliosides in salivary gland complications of diabetes
- Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo
- Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice
- Atrial natriuretic peptide promotes pancreatic islet β-cell growth and Akt/Foxo1a/cyclin D2 signaling
- Association of IL‐18 promoter polymorphisms with predisposition to Type 1 diabetes
- Divergence between Genetic Determinants of IGF2 Transcription Levels in Leukocytes and of IDDM2-Encoded Susceptibility to Type 1 diabetes
- Pathogenesis of insulin-dependent diabetes mellitus
- PDX-1 mediates glucose responsiveness of GAD67, but not GAD65, gene transcription in islets of Langerhans
- Bioactive GLP-1 in gut, receptor expression in pancreas, and insulin response to GLP-1 in diabetes-prone rats
- Improved β-Cell Survival and Reduced Insulitis in a Type 1 Diabetic Rat Model After Treatment With a β-Cell–Selective KATP Channel Opener
- Correlation between residual β-cell function and age at onset of spontaneous diabetes in Long Evans Tokushima Lean rats
- Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway
- Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset
- Enhanced alloxan-induced β-cell damage and delayed recovery from hyperglycemia in mice lacking extracellular-superoxide dismutase
- Pioglitazone prevents mice from multiple low-dose streptozotocin-induced insulitis and diabetes
- Drug insight: New immunomodulatory therapies in type 1 diabetes
- Study of interleukin-10 promoter region polymorphisms (− 1082A/G,− 819T/C and− 592A/C) in type 1 diabetes mellitus in Turkish population
- Role of innate immunity in triggering and tuning of autoimmune diabetes
- The GM2-1 Ganglioside Islet Autoantigen in Insulin-Dependent diabetes Mellitus Is Expressed in Secretory Granules and Is Notβ-Cell Specific
- Cutting edge: B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice
- Cellular and molecular roles of β cell autoantigens, macrophages and T cells in the pathogenesis of autoimmune diabetes
- Coxsackievirus B3 infection affects metal-binding/transporting proteins and trace elements in the pancreas in mice
- Immunokinetics of autoreactive CD4 T cells in blood: a reporter for the “hit-and-run” autoimmune attack on pancreas and diabetes progression
- Processing in the endoplasmic reticulum generates an epitope on the insulin A chain that stimulates diabetogenic CD8 T cell responses
- Association between IL-18 gene promoter polymorphisms and CTLA-4 gene 49A/G polymorphism in Japanese patients with type 1 diabetes
- Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-γ-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine …
- Follow-up of exocrine pancreatic function in type-1 diabetes mellitus
- ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart
- Arginase expression and modulation of IL-1β-induced nitric oxide generation in rat and human islets of Langerhans
- Impaired primary immune response in type-1 diabetes. Functional impairment at the level of APCs and T-cells
- Acute onset of type 1 diabetes accompanied by acute hepatitis C: the potential role of proinflammatory cytokine in the pathogenesis of autoimmune diabetes
- Regeneration of pancreatic endocrine cells in interferon-gamma transgenic mice
- Glucose-stimulated and self-limiting insulin production by glucose 6-phosphatase promoter driven insulin expression in hepatoma cells
- Glucagon-like peptide-2 reduces intestinal permeability but does not modify the onset of type 1 diabetes in the nonobese diabetic mouse
- Differential immune response to B: 9-23 insulin 1 and insulin 2 peptides in animal models of type 1 diabetes
- Activated T lymphocytes from patients with high risk of type I diabetes mellitus have different ability to produce interferon-γ, interleukin-6 and interleukin-10 and …
- Remission of diabetes mellitus in cats with diabetic ketoacidosis
- VIP and tolerance induction in autoimmunity
- Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease
- The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non–class II gene
- Biochemical Characteristics of the γ-Aminobutyric Acid System in the Insulinoma Cell Lines HIT-T15, RIN-m5F, βTC3, and Comparison with Rat Brain
- An Imidazoline Compound Completely Counteracts Interleukin-1β toxic Effects to Rat pancreatic Islet β cells
- Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
- Streptozotocin-induced type 1 diabetes mellitus alters the morphology, secretory function and acyl lipid contents in the isolated rat parotid salivary gland
- Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors
- First signature of islet β-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules
- Polymorphism of bovine beta-casein and its potential effect on human health
- Paraneoplastic encephalomyelitis associated with pancreatic tumor and anti-GAD antibodies
- Effect of proinflammatory cytokines on gene expression of the diabetes-associated autoantigen IA-2 in INS-1 cells
- Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
- Bovine serum albumin and insulin-dependent diabetes mellitus: is cow’s milk still a possible toxicological causative agent of diabetes?
- Editorial [Hot Topic: Nutritional Modulation of Autoimmune diabetes (Guest Editor: Fraser W. Scott)]
- Antihyperglycemic and antioxidative potential of Matricaria chamomilla L. in streptozotocin-induced diabetic rats
- Prophylactic Oral Administration of Metabolically Active Insulin Entrapped in Isobutylcyanoacrylate Nanocapsules Reduces the Incidence of diabetes inNonobese …
- Induction, acceleration or prevention of autoimmunity by molecular mimicry
- Diet promotes β-cell loss by apoptosis in prediabetic nonobese diabetic mice
- Molecular and biological analysis of echovirus 9 strain isolated from a diabetic child
- Effects of Syzygium Cumini bark on blood glucose, plasma insulin and C-peptide in streptozotocininduced diabetic rats
- Genetic association of HLA DQB1 with CD4+ CD25+ high T-cell apoptosis in type 1 diabetes
- Expression of somatostatin receptor subtypes 1–5 in pancreatic islets of normoglycaemic and diabetic NOD mice
- Still Waiting Their Turn
- Killer cell immunoglobulin‐like receptor genotypes in Japanese patients with type 1 diabetes
- Distinct local immunogenic stimuli dictate differential requirements for CD4+ and CD8+ T cell subsets in the pathogenesis of spontaneous autoimmune diabetes
- Islet glutamic acid decarboxylase modified by reactive oxygen species is recognized by antibodies from patients with type 1 diabetes mellitus
- Type 1 diabetes intervention trials 2007: where are we and where are we going?
- Tertiary lymphoid structures in the pancreas promote selection of B lymphocytes in autoimmune diabetes
- Interleukin-1β swiftly down-regulates UCP-2 mRNA in β-cells by mechanisms not directly coupled to toxicity
- IFN-γ affects homing of diabetogenic T cells
- Polymorphisms of interferon-γ gene CA-Repeat and interleukin-10 promoter region (-592A/C) in Japanese type I diabetes
- Improved efficacy of a tolerizing DNA vaccine for reversal of hyperglycemia through enhancement of gene expression and localization to intracellular sites
- A review on the mechanisms involved in hyperglycemia induced by organophosphorus pesticides
- Direct administration of interleukin-1 and interferon-γ to rat pancreas leads to the in vivo production of nitric oxide and expression of inducible nitric oxide synthase and …
- Screening of diabetes, thyroid, and celiac diseases-related autoantibodies in a sample of Turkish children with type 1 diabetes and their siblings
- Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes
- Influence of sex and age at onset on autoantibodies against insulin, GAD65 and IA2 in recent onset type 1 diabetic patients
- The effect of long-term swimming program on glycemia control in 14–19-year aged healthy girls and girls with type 1 diabetes mellitus
- Prostaglandin E2 mediates inhibition of insulin secretion by interleukin-1β
- Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes in an IL-10-dependent manner
- IL4 and IL4R α Genes Are Not Linked or Associated with Type 1 diabetes
- Antidiabetic activity of angelan isolated from Angelica gigas Nakai
- Experimental diabetes treated with Achillea santolina: Effect on pancreatic oxidative parameters
- Infections and autoimmune diseases
- Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice
- Prevention of encephalomyocarditis virus-induced diabetes in mice by inhibition of the tyrosine kinase signalling pathway and subsequent suppression of nitric oxide …
- Homotypic cell contact enhances insulin but not glucagon secretion
- Sex‐specific association of the human PTPN22 1858T‐allele with type 1 diabetes
- Short‐acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus
- Adipose tissue-derived nerve growth factor and brain-derived neurotrophic factor: results from experimental stress and diabetes
- Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age
- Microorganisms and autoimmunity: making the barren field fertile?
- Phenotypic and genetic changes in coxsackievirus B5 following repeated passage in mouse pancreas in vivo
- Cytokines: promoters and dampeners of autoimmunity
- Apoptotic and effector pathways in autoimmunity
- High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase
- Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia …
- Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells
- Decreased prevalence of atopic diseases in children with diabetes
- Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line
- Corticosteroid-responsive diabetes mellitus associated with autoimmune pancreatitis
- Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down …
- Survey of mRNAs encoding zinc transporters and other metal complexing proteins in pancreatic islets of rats from birth to adulthood: similar patterns in the Sprague …
- Impaired CD4+ and CD8+ T cell phenotype and reduced chemokine secretion in recent-onset type 1 diabetic children
- Autoantibodies against Aromatic l-Amino Acid Decarboxylase Identifies a Subgroup of Patients with Addison’s Disease
- A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse
- Remodeling of the innervation of pancreatic islets accompanies insulitis preceding onset of diabetes in the NOD mouse
- Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 diabetes Genetics Consortium
- Amomum xanthoides extract prevents cytokine-induced cell death of RINm5F cells through the inhibition of nitric oxide formation
- The possible role of enteroviruses in diabetes mellitus
- Pediatric Diabetic Ketoacidosis
- Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice
- Cytokines and chemokines in virus-induced autoimmunity
- Th1-like cytokine production profile and individual specific alterations in TCRBV-gene usage of T cells from newly diagnosed type 1 diabetes patients after stimulation …
- Initiation of autoimmunity
- The effect of local production of cytokines in the pathogenesis of insulin-dependent diabetes mellitus
- The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells
- A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families
- Natural killer cells in human autoimmunity
- pancreatic lymph nodes are required for priming of β cell reactive T cells in NOD mice
- Developmental Biology of the β-Cell
- Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir
- Complete nucleotide sequence of a coxsackievirus B4 strain that establishes infection in ICR mice pancreas and induces glucose intolerance
- Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression
- IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk
- A mathematical model for pattern of change in β-cell reserve and factors affecting residual reserve within the first 2 years of Type 1 diabetes
- Effect of prostaglandins against alloxan-induced diabetes mellitus
- Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets
- Human leukocyte antigen class IB and C loci contribute to Type 1 diabetes (T1D) susceptibility and age at T1D onset
- Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to β cell damage
- Interleukin-1 stimulates β-cell necrosis and release of the immunological adjuvant HMGB1
- Cell type-specific activation of metabolism reveals that β-cell secretion suppresses glucagon release from α-cells in rat pancreatic islets
- NK3-like NK cells are involved in protective effect of polyinosinic-polycytidylic acid on type 1 diabetes in nonobese diabetic mice
- Association of fulminant type 1 diabetes with pregnancy
- Combination therapy of Nigella sativa and human parathyroid hormone on bone mass, biomechanical behavior and structure in streptozotocin-induced diabetic rats
- The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice
- Increased Transcriptional Preproinsulin II β-Cell Activity in Neonatal Nonobese Diabetic Mice: In Situ Hybridization Analysis
- Regulation of diabetes development by regulatory T cells in pancreatic islet antigen-specific TCR transgenic nonobese diabetic mice
- diabetes produced in mice by smoked/cured mutton
- Effective control of blood glucose status and toxicity in streptozotocin-induced diabetic rats by orally administration of vanadate in an herbal decoction
- Difficulties in assessing the relationship, if any, between mumps vaccination and diabetes mellitus in childhood
- Infusion of UVB-treated splenic stromal cells induces suppression of β cell antigen-specific T cell responses in NOD mice
- High prevalence of manifestations of gastric autoimmunity in parietal cell antibody-positive type 1 (insulin-dependent) diabetic patients
- Susceptibility to type 1 diabetes conferred by the PTPN22C1858T polymorphism in the Spanish population
- Differential responses of the growth hormone axis in two rat models of streptozotocin-induced insulinopenic diabetes
- Kinin B1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice
- B Cells Promote Intra-Islet CD8 Cytotoxic T Lymphocyte Survival To Enhance Type 1 diabetes
- Combination of HLA DR and DQ molecules determine the susceptibility to Insulin Dependent diabetes Mellitus in Iraqi Patients
- Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention
- Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of β cell autoantigens
- Animal models of spontaneous autoimmune diabetes: notes on their relevance to the human disease
- Hypoglycemic effect of Swietenia macrophylla seeds against type II diabetes
- Lack of effect of vitamin D administration during pregnancy and early life on diabetes incidence in the non-obese diabetic mouse
- Immune mechanisms leading to type 1 insulin-dependent diabetes mellitus
- Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
- Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin-dependent) diabetes mellitus
- Early reaction of astroglial cells in rat hippocampus to streptozotocin-induced diabetes
- The identification and sequence analysis of a new Reg3gamma and Reg2 in the Syrian golden hamster
- IDO mediates TLR9-driven protection from experimental autoimmune diabetes
- Zinc influx and physiological consequences in the β-insulinoma cell line, Min6
- New insights into managing the risk of hypoglycaemia associated with intermittent high-intensity exercise in individuals with type 1 diabetes mellitus: implications for …
- The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
- [Ca2+]i regulates trafficking of Cav1.3 (α1D Ca2+ channel) in insulin-secreting cells
- … CT60 Polymorphism May Not Be Affected by Vitamin D Receptor Gene Bsm I Polymorphism or HLA DR9 in Autoimmune‐Related Type 1 diabetes in the Japanese
- Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
- Increased Level of Interferon-α in Blood of Patients with Insulin-Dependent diabetes Mellitus: Relationship with Coxsackievirus B Infection
- … and interaction of the TNF‐alpha gene with other pro‐and anti‐inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India
- An insight into the genetics of type 1 diabetes
- An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue …
- Effector lymphocytes in autoimmunity
- NOD mouse diabetes: the ubiquitous mouse hsp60 is a β-cell target antigen of autoimmune T cells
- Centromeric interval of chromosome 4 derived from C57BL/6 mice accelerates type 1 diabetes in NOD. CD72b congenic mice
- The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas
- Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes
- Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery
- Serum IFN‐γ and IL‐10 levels are associated with disease progression in non‐obese diabetic mice
- Protective role for cytosolic phospholipase A2α in autoimmune diabetes of mice
- T regulatory cells in autoimmune diabetes: past challenges, future prospects
- Modulation and detection of IDDM by membrane associated antigens from the islet beta cell line NIT-1
- T-cell reactivity to insulin peptide A1–12 in children with recently diagnosed type 1 diabetes or multiple β-cell autoantibodies
- Polymorphic variation in the CBLB gene in human type 1 diabetes
- IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-γ-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL …
- Islet β-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets
- Gene expression profiling in type 1 diabetes prone NOD mice immunized with a disease protective autoantigenic peptide
- Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes
- The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1
- Failure of high-dose insulin treatment to increase β-cell insulin content in diabetic non obese diabetic (NOD) mice
- IL-18 inhibits diabetes development in nonobese diabetic mice by counterregulation of Th1-dependent destructive insulitis
- Disease-associated autoantibodies as surrogate markers of type 1 diabetes in young children at increased genetic risk
- Low protein diet confers resistance to the inhibitory effects of interleukin 1β on insulin secretion in pancreatic islets☆
- Combined insulin and bicarbonate therapy elicits cerebral edema in a juvenile mouse model of diabetic ketoacidosis
- Retinoids differentially regulate the progression of autoimmune diabetes in three preclinical models in mice
- Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats
- Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats
- Monoclonal antibody 76F distinguishes IA-2 from IA-2β and overlaps an autoantibody epitope
- Prolonged Viral RNA Detection in Blood and Lymphoid Tissues from Coxsackievirus B4 E2 Orally‐Inoculated Swiss Mice
- Functional variants in SUMO4, TAB2, and NFκB and the risk of type 1 diabetes
- Potential health benefits of avenanthramides of oats
- Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
- Prolactin receptors are critical to the adaptation of islets to pregnancy
- The role of somatolactogenic hormones and receptors in the growth and function of the endocrine pancreas
- Vitamin D Supplementation in Early Childhood and
- A wheat-based, diabetes-promoting diet induces a Th1-type cytokine bias in the gut of NOD mice
- Islet β-Cell Apoptosis Triggered in Vivo by Interleukin-1β Is Not Related to the Inducible Nitric Oxide Synthase Pathway: Evidence for Mitochondrial Function …
- Inhibition of membrane type-1 matrix metalloproteinase by cancer drugs interferes with the homing of diabetogenic T cells into the pancreas
- Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
- Environmental determinants: The role of viruses and standard of hygiene
- Insulin trigger for diabetes
- Combinations of common chronic paediatric diseases deviate the immune response in diverging directions
- Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas
- Soluble adhesion molecules in preclinical type 1 diabetes
- Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease
- Extracellular lysosome‐associated membrane protein‐1 (LAMP‐1) mediates autoimmune disease progression in the NOD model of type 1 diabetes
- Association of the PTPN22 polymorphism C1858T with type 1 diabetes mellitus
- Relative diabetogenic properties of islet-specific Tc1 and Tc2 cells in immunocompetent hosts
- Tolerance mechanisms in murine autoimmune diabetes induced by anti-ICAM-1/LFA-1 mAb and anti-CD8 mAb
- Involvement of Gut Immune System in the pathogenesis of type 1 diabetes: detection of T cell reactivity to Gliadin
- The NF-kB pathway as a potential target for autoimmune disease therapy
- Prevalence of permanent neonatal diabetes in Slovakia and successful replacement of insulin with sulfonylurea therapy in KCNJ11 and ABCC8 mutation carriers
- Characterization and isolation of a β-cell surface receptor for diabetogenic EMC-D virus and studies on the relationship between receptor number and pathogenesis in …
- Characterization of anti-islet cytotoxic human T-cell clones from patients with type 1 diabetes mellitus
- Association of the chromosomal region 2q35 with type 1 diabetes mellitus in the Russian patients from Moscow
- Biochemical studies on the effect of Terminalia chebula on the levels of glycoproteins in streptozotocin-induced experimental diabetes in rats.
- … early diabetes sensitivity to multiple low doses of streptozotocin than nondiabetes-prone CD-1 mice: initial beta-cell damage a key trigger for type 1 diabetes?
- CD4+ CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
- Where CD4+CD25+ T reg cells impinge on autoimmune diabetes
- Diabetic neuropathy models: Are they relevant?
- Absence of Heterozygous K83E and R257X Mutations of the AIRE-1 Gene in 46 Children with Type 1 diabetes and 44 Children with Graves’ Disease
- The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane
- Hypoglycemic and antioxidative effects of fermented chaga mushroom (Inonotus obliquus) on streptozotocin-induced diabetic rats
- PYY in the expanding pancreatic epithelium
- T-cell reactivity to glutamic acid decarboxylase in stiff-man syndrome and cerebellar ataxia associated with polyendocrine autoimmunity
- Web-Based Simulations for Dynamic Variations in Blood-Glucose Concentration of Patients with Type 1 diabetes
- Enhanced β-cell mass without increased proliferation following chronic mild glucose infusion
- Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient
- Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Δψm) in pancreatic RINm5F cells: prevention by Bcl-2
- Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic …
- IL-4 AND INTERFERON GAMMA IN RECENTLY DIAGNOSED TYPE I diabetes, A CASE-CONTROL STUDY
- A novel drug delivery system for type 1 diabetes: Insulin-mimetic vanadyl-poly (γ-glutamic acid) complex
- Macrophage activation phenotypes in type 1 diabetes pathogenesis and therapy: Master thesis
- Norepinephrine and epinephrine-deficient mice are hyperinsulinemic and have lower blood glucose
- Relationships among islet cell antibodies, residual β-cell function, and metabolic control in patients with insulin-dependent diabetes mellitus of long duration: use of a …
- Mapping of the murine type 1 diabetes locus Idd20 by genetic interaction
- Effect of targeted disruption of signal transducer and activator of transcription (Stat) 4 and Stat6 genes on the autoimmune diabetes development induced by multiple …
- Impaired glucagon response to sympathetic nerve stimulation in the BB diabetic rat: effect of early sympathetic islet neuropathy
- Poly (lactide-co-glycolide)-Polymethacrylate Nanoparticles for Intramuscular Delivery of Plasmid Encoding Interleukin-10 to Prevent Autoimmune diabetes in Mice
- Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats
- The new paradigm of T-cell homeostatic proliferation-induced autoimmunity
- Polyunsaturated fatty acids alter the rules of engagement
- No evidence for association of the TATA-box binding protein glutamine repeat sequence or the flanking chromosome 6q27 region with type 1 diabetes
- Coxsackie B virus infection of mice: inoculation by the oral route protects the pancreas from damage, but not from infection
- Distribution of C→ T and T→ C polymorphisms of the urokinase-type plasminogen activator gene in children with type 1 diabetes mellitus and insulin resistance
- Daily nasal inoculation with the insulin gene ameliorates diabetes in mice
- Complete nucleotide sequence of a Coxsackievirus B‐4 strain capable of establishing persistent infection in human pancreatic islet cells: Effects on insulin release …
- Nuclear factor-κB translocation mediates double-stranded ribonucleic acid-induced NIT-1 β-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor …
- Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab
- Essential roles of TGF‐β in anti‐CD3 antibody therapy: reversal of diabetes in nonobese diabetic mice independent of Foxp3+CD4+ regulatory T cells
- Clioquinol effects on tissue chelatable zinc in mice
- Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells
- Localization of insulinoma associated protein 2, IA-2 in mouse neuroendocrine tissues using two novel monoclonal antibodies
- Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion
- The T-cell receptor beta chain CDR3 region of BV8S1/BJ1S5 transcripts in type 1 diabetes
- HYPERINSULINISM IN INFANCY: TOPOGRAPHICAL LOCALISATION OF A pancreatic FOCAL LESION BY TRANSHEPATIC PORTAL CATHETERISM …
- Therapeutic manipulation of iNKT cells in autoimmunity: modes of action and potential risks
- Persistent infection of human thymic epithelial cells by coxsackievirus B4
- Tacrolimus, but not cyclosporine A, significantly increases expression of ICAM‐1 and IFN‐γ in the NOD mouse
- Beta cell antigens
- Inhibition of type 1 diabetic hyperalgesia in streptozotocin-induced Wistar versus spontaneous gene-prone BB/Worchester rats: efficacy of a selective bradykinin B1 …
- Glucose transport in brain and retina: implications in the management and complications of diabetes
- Evidence for a Type 1 diabetes Susceptibility Locus (IDDM10) on Chromosome 10p11‐q11 in a Russian Population
- Colocalization of γ-aminobutyrate and gastrin in the rat antrum: An immunocytochemical and in situ hybridization study
- Cyclosporin depresses pancreatic islet expression of antigens for islet cell autoantibodies in non obese diabetic mice
- Fibronectin and laminin induce expression of islet cell markers in hepatic oval cells in culture
- Cell type specific and glucose responsive expression of interleukin-4 by using insulin promoter and water soluble lipopolymer
- Genetic control of diabetes progression
- … of C [arrow right] T and T [arrow right] C polymorphisms of the urokinase-type plasminogen activator gene in children with type 1 diabetes mellitus and insulin …
- Stimulation of endothelial nitric oxide synthase by proinsulin C-peptide
- Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice
- Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas
- Codelivery of a tea extract prevents morbidity and mortality associated with oral vanadate therapy in streptozotocin-induced diabetic rats
- Association analyses of the vitamin D receptor gene in 1654 families with type I diabetes
- The weight of leptin in immunity
- Development of autoimmune diabetes in glutamic acid decarboxylase 65 (GAD65) knockout NOD mice
- Proapoptosis and antiapoptosis-related molecules during postnatal pancreas development in control and nonobese diabetic mice: relationship with …
- Loss of invariant chain protects nonobese diabetic mice against type 1 diabetes
- Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21
- Dynamic changes in CD4+ CD25+ high T cell apoptosis after the diagnosis of type 1 diabetes
- Bacterial and plant enterotoxin B subunit-autoantigen fusion proteins suppress diabetes insulitis
- Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
- γδ T-cells alterations in the peripheral blood of high risk diabetes type 1 subjects with subclinical pancreatic B-cells impairment
- Coxsackievirus-mediated hyperglycemia is enhanced by reinfection and this occurs independent of T cells
- Glucose Dependence of Imidazoline-Induced Insulin Secretion: Different Characteristics of Two ATP-Sensitive K+ Channel–Blocking Compounds
- Common susceptibility and transmission pattern of human leukocyte antigen DRB1-DQB1 haplotypes to Korean and Caucasian patients with type 1 diabetes
- Proinsulin C-peptide activates vagus efferent output in rats
- Primary Sjögren’s syndrome and deficiency of ICA69
- 12: Is multiple injection therapy the treatment of choice in type 1 diabetes?
- Self-representation in the thymus: an extended view
- Effect of X‐and Y‐Box Deletions on the Development of diabetes in H‐2Eα‐Chain Transgenic Nonobese Diabetic Mice
- Obstacles to identifying viruses that cause autoimmune disease
- Autoimmune diabetes mellitus—much progress, but many challenges
- E-cadherin interactions regulate β-cell proliferation in islet-like structures
- Protein tyrosine phosphatase-like protein IA2-antibodies plus glutamic acid decarboxylase 65 antibodies (GADA) indicates autoimmunity as frequently as islet cell …
- Mechanisms and results of the antibody-dependent enhancement of viral infections and role in the pathogenesis of coxsackievirus B-induced diseases
- Oral administration of branched chain amino acids improves virus-induced glucose intolerance in mice
- Intramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in mice
- Sumoylation of Pdx1 is associated with its nuclear localization and insulin gene activation
- Gene expression of pancreatic glutamic acid decarboxylase in the nonobese diabetic mouse
- B cells are crucial for determinant spreading of T cell autoimmunity among β cell antigens in diabetes-prone nonobese diabetic mice
- Minority participation in health research—facts and fiction
- Cytokine-induced PGE2 formation is reduced from iNOS deficient murine islets
- IL-23 drives pathogenic IL-17-producing CD8+ T cells
- FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells
- Glucagon inhibits ghrelin secretion in humans
- Intraperitoneal co-administration of thymosin α-1 ameliorates streptozotocin-induced pancreatic lesions and diabetes in C57BL/6 mice
- Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro
- Islet abnormalities associated with an early influx of dendritic cells and macrophages in NOD and NODscid mice
- Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of a cholera toxin B subunit–insulin B chain fusion protein vaccine produced in …
- The autoimmune contrivance: genetics in the mouse model
- Glucose regulates the release of orexin-a from the endocrine pancreas
- Transcriptional regulation of type I diabetes by NF-κB
- Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air?
- Overexpression of the Pdx-1 homeodomain transcription factor impairs glucose metabolism in cultured rat hepatocytes
- Extracellular matrix distribution and islet morphology in the early postnatal pancreas: anomalies in the non-obese diabetic mouse
- Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes …
- Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal …
- Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain
- Role of bradykinin B1 receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice
- Low expression of insulin in the thymus of non-obese diabetic mice
- Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes
- Modulation of vasoconstrictor and dilator pancreatic metabolites in streptozotocine diabetic rats:: Effect of bradykinin blockage and NO inhibition
- Human bone marrow-derived mesenchymal stem cells differentiate into insulin, somatostatin and glucagon expressing cells
- Effects of Syzygium cordatum (Hochst.)[Myrtaceae] leaf extract on plasma glucose and hepatic glycogen in streptozotocin-induced diabetic rats
- Detection of autoantibodies to protein tyrosine phosphatase-like protein IA-2 with a novel time-resolved fluorimetric assay
- How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets
- CD8+ T lymphocytes specific for glutamic acid decarboxylase 90–98 epitope mediate diabetes in NODSCID mouse
- The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression
- Imaging of the brain in children with type I diabetes mellitus
- Immunohistochemical evidence for the presence of glucokinase in the gonadotropes and thyrotropes of the anterior pituitary gland of rat and monkey
- Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes
- Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis
- Oral DNA vaccination with a plasmid encoding soluble ICAM-1 modulates cytokine expression profiles in nonobese diabetic mice
- Immunoregulation during disease progression in prediabetic NOD mice: inverse expression of arginase and prostaglandin H synthase 2 vs. interleukin-15
- Evaluation of hypoglycemic activity of Opuntia dillenii haw fruit juice in streptozotocin-induced diabetic rats
- Good riddance: thymocyte clonal deletion prevents autoimmunity
- Is antigen specificity of autoreactive T cells the key to islet entry?
- Sex steroids influence pancreatic islet hypertrophy and subsequent autoimmune infiltration in nonobese diabetic (NOD) and NODscid mice
- Maternal diabetes adversely affects preovulatory oocyte maturation, development, and granulosa cell apoptosis
- Evidence for immunological priming and increased frequency of CD4+ CD25+ cord blood T cells in children born to mothers with type 1 diabetes
- The etiology of autoimmune diabetes and thyroiditis: evidence for common genetic susceptibility
- Imprinted and Genotype-specific Expression of Genes at theIDDM2Locus in Pancreas and Leucocytes
- Effect of X-and Y-Box Deletions on the Development of diabetes in H-2Eα-Chain Transgenic Nonobese Diabetic Mice
- Neurogenin3 triggers beta-cell differentiation of retinoic acid-derived endoderm cells
- Glucose lowering efficacy of the aqueous stem bark extract of Trema orientalis (Linn) Blume in normal and streptozotocin diabetic rats
- Systemic administration of agonist peptide blocks the progression of spontaneous CD8-mediated autoimmune diabetes in transgenic mice without bystander damage
- MCP-1 and MIP-2 expression and production in BB diabetic rat: effect of chronic hypoxia
- Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice
- Aerosol insulin induces regulatory CD8 γδ T cells that prevent murine insulin-dependent diabetes
- Hyperinsulinism and Beckwith-Wiedemann syndrome
- Interleukin-21 as a new therapeutic target for immune-mediated diseases
- Early and quantal (by litter) expression of insulin autoantibodies in the nonobese diabetic mice predict early diabetes onset
- Sustained enhancement of Ca2+ influx by glibenclamide induces apoptosis in RINm5F cells
- The role of ghrelin and ghrelin analogues in wasting disease
- N-3 fatty acids modulate Th1 and Th2 dichotomy in diabetic pregnancy and macrosomia
- Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease
- The role of the activating receptor NKG2D in autoimmunity
- Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate
- Insulin Gene Expression
- Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes
- Immunology section
- Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity
- Demonstration of natural autoantibodies against the neurofilament protein α-internexin in sera of patients with endocrine autoimmunity and healthy individuals
- DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
- The Reactive d-Glucopyranose Moiety of Streptozotocin Is Responsible for Activation of Macrophages and Subsequent Stimulation of CD8+ T Cells
- Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease …
- Streptozotocin-induced diabetes and glucocorticoid receptor regulation: tissue-and age-specific variation
- Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: Implications for the …
- Antidiabetogenic effect of pentoxifylline is associated with systemic and target tissue modulation of cytokines and nitric oxide production
- Plant-based vaccines for protection against infectious and autoimmune diseases
- Serum Thymic Factor Prevents LPS‐Induced pancreatic Cell Damage in Mice via Up‐Regulation of Bcl‐2 Expression in Pancreas
- Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression
- Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice
- Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice
- Global profiling of double stranded RNA-and IFN-γ-induced genes in rat pancreatic beta cells
- Gene expression of islet cell antigen p69 in human, mouse, and rat
- Molecular profile of the T cell receptors of regulatory and effector CD4+ T cells recognizing overlapping determinants on glutamic acid decarboxylase (524–543)
- Impact of plastic adhesion in vitro on analysis of Th1 and Th2 cytokines and immune cell distribution from mice with multiple low-dose streptozotocin-induced diabetes
- β cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct
- Insulin-Dependent diabetes Mellitus (IDDM) Is Associated with CTLA4 Polymorphisms in Multiple Ethnic Groups
- Cytokines affect PDX-1 expression, insulin and proinsulin secretion from iNOS deficient murine islets
- PD-1 and its ligands in T-cell immunity
- Elevated plasma levels of glucagon-like peptide-1 after oral glucose ingestion in patients with pancreatic diabetes
- Reciprocal regulation between natural killer cells and autoreactive T cells
- Self and non-self antigen in diabetic autoimmunity: molecules and mechanisms
- Dual T cell receptor expressing CD8+ T cells with tumor-and self-specificity can inhibit tumor growth without causing severe autoimmunity
- CD18 deficiency protects against multiple low-dose streptozotocin-induced diabetes
- Diabetic Perspectives
- Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells
- Autoimmune thyroid disease: new models of cell death in autoimmunity
- Autocrine and paracrine roles of sphingosine-1-phosphate
- Prevention of Spontaneous Autoimmune diabetes in NOD Mice by Transferring in VitroAntigen-Pulsed Syngeneic Dendritic Cells
- Insulitis and mechanisms of disease resistance: studies in an animal model of insulin dependent diabetes mellitus
- Insulin-dependent diabetes mellitus in non-DR3/non-DR4 subjects
- Cytokines in autoimmunity
- Chronic alcohol intake differently influences glucose metabolism according to nutritional status
- Insights into autoimmunity gained from structural analysis of MHC–peptide complexes
- Neonatal diabetes mellitus and cerebellar hypoplasia/agenesis: report of a new recessive syndrome
- Toll‐like receptors and diabetes
- Identifying tumor antigens in endocrine malignancies
- The initiation of autoimmune diabetes
- No evidence for activation of TH1 or TH17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D
- Th1 and Th2 cytokines exert regulatory effects upon islet microvascular areas in the NOD mouse
- … K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic α-cells: effects on …
- Intra-Peritoneal Administration of Interleukin-1β Induces Impaired Insulin Release from the Perfused Rat Pancreas
- Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin …
- Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen
- CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen
- Novel insulin/GIP co‐producing cell lines provide unexpected insights into Gut K‐cell function in vivo
- Transfer of diabetes from prediabetic NOD mice to NOD-SCID/SCID mice: association with pancreatic insulin content
- Detection of glutamic acid decarboxylase (GAD) autoantibodies by indirect immunofluorescence using CHO cells expressing recombinant human GAD65
- … ′, 5′-oligoadenylate synthetase (2′ 5′ AS) antiviral enzyme activity and apoptosis following IFN-α or poly (I: C) treatment than pancreatic alpha TC3 cells
- Specific Inhibition of Autoimmune T Cell Transmigration Contributes to β Cell Functionality and Insulin Synthesis in Non-obese Diabetic (NOD) Mice
- pancreatic hormone expression in the murine thymus: localization in dendritic cells and macrophages
- Inhibition of Ca2+-Independent Phospholipase A2 Results in Insufficient Insulin Secretion and Impaired Glucose Tolerance
- Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population
- Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2Kd that stimulates CD8 T cells in insulin-dependent diabetes …
- Long‐Term Expression of an HLA‐DQ Molecule in the EBV‐Transformed Bare Lymphocyte Cell Line, BLS‐1, using a Plasmid Vector
- diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene …
- Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells
- Linomide Increases Plasma Corticosterone in Normal Rats, but does not Prevent the Inhibitory Action of IL-1 on β-cells in Vivo or ex Vivo
- Glibenclamide prevents increased extracellular matrix formation induced by high glucose concentration in mesangial cells
- NOD mice are defective in proteasome production and activation of NF-κB
- Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
- T‐cell tolerance and autoimmunity to systemic and tissue‐restricted self‐antigens
- Somatostatin and its receptors in the development of the endocrine pancreas
- Peptide YY is secreted after oral glucose administration in a gender-specific manner
- Influence of a non-NK complex region of chromosome 6 on CD4+ invariant NK T cell homeostasis
- An extension to the compartmental model of type 1 diabetic patients to reproduce exercise periods with glycogen depletion and replenishment
- Relative increase in IgG antibodies to Pseudomonas aeruginosa 60-kDa GroEL in prediabetic patients with cystic fibrosis
- Dendritic cell vaccination with xenogenic polypeptide hormone induces tumor rejection in neuroendocrine cancer
- Selected contribution: Association of gender-related LMP2 inactivation with autoimmune pathogenesis
- Visualizing immune system complexity
- Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene
- Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent
- Glucose-and metabolically regulated hepatic insulin gene therapy for diabetes
- Monoclonal autoantibodies from insulin-dependent diabetic patients: autoantibodies against β-cell surface or cytoplasmic antigens
- βIV spectrin, a new spectrin localized at axon initial segments and nodes of Ranvier in the central and peripheral nervous system
- A Th1-recognized peptide P277, when tandemly repeated, enhances a Th2 immune response toward effective vaccines against autoimmune diabetes in nonobese …
- CD154-dependent priming of diabetogenic CD4+ T cells dissociated from activation of antigen-presenting cells
- IFN-γ-dependent regulatory circuits in immune inflammation highlighted in diabetes
- Islet endocrine-cell behavior from birth onward in mice with the nonobese diabetic genetic background
- Identical β cell-specific CD8+ T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets
- Proteinn-X, pancreatic Stone-, pancreatic Thread-, reg-Protein, P19, Lithostathine, and Now What
- The role of viruses in type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals
- Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans
- … Greater-Oligoadenylate Synthetase (AS) Antiviral Enzyme Activity and Apoptosis Following IFN-or Poly (I: C) Treatment than pancreatic Alpha TC3 Cells
- Suppressive effects of a selective inducible nitric oxide synthase (iNOS) inhibitor on pancreatic beta-cell dysfunction
- HIP/PAP, a member of the reg family, is expressed in glucagon-producing enteropancreatic endocrine cells and tumors
- Antibodies to CD1d enhance thymic expression of invariant NKT TCR and increase the presence of NOD thymic invariant NKT cells
- Effect of Linomide on adhesion molecules, TNF-α, nitrogen oxide, and cell adhesion
- CTSL2 as a candidate gene for autoimmune diseases: genetic and functional studies to explore its role in type 1 diabetes and myasthenia gravis
- Early neonatal events and the disease incidence in nonobese diabetic mice
- Expression of cyclooxygenase‐2 in intestinal goblet cells of pre‐diabetic NOD mice
- Celiac disease-associated autoimmune endocrinopathies
- Ghrelin and insulin gene expression changes in streptozotocin-induced diabetic rats after rosiglitazone pretreatment
- The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form
- Virus-Induced Autoimmune diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex
- Interferon-α-induced endogenous superantigen: a model linking environment and autoimmunity
- S100A1 and S100B expression and target proteins in type I diabetes
- Transgenic Ly-49A inhibits antigen-driven T cell activation and delays diabetes
- The coxsackie-and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis
- Major histocompatibility class II genes polymorphism in insulin dependent diabetes mellitus with or without associated thyroid autoimmunity
- The enlarged population of marginal zone/CD1dhigh B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11
- Dense-core vesicle proteins IA-2 and IA-2β affect renin synthesis and secretion through the β-adrenergic pathway
- Probable mechanism of the antihyperglycemic effect of standardized extract from Momordica charantia in streptozotocin diabetic rats
- Patent application title: CHLOROPLASTS ENGINEERED TO EXPRESS PHARMACEUTICAL PROTEINS IN EDIBLE PLANTS Inventors: Henry Daniell (Winter …
- Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial
- A novel role for CD4+ T cells in the control of cachexia
- Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia
- Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination
- IL-10 impacts autoimmune diabetes via a CD8+ T cell pathway circumventing the requirement for CD4+ T and B lymphocytes
- IL-18 in autoimmunity
- Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses
- Plant-made vaccine antigens and biopharmaceuticals
- Informant consensus selection method: A reliability assessment on medicinal plants used in north western Nigeria for the treatment of diabetes mellitus
- In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter …
- Inducible nitric oxide synthase-derived nitric oxide in gene regulation, cell death and cell survival
- Exogenous activin increases the proportion of insulin cells in the developing chick pancreas in culture
- Viral protein VP4 is a target of human antibodies enhancing coxsackievirus B4-and B3-induced synthesis of alpha interferon
- Paternally TransmittedIDDM2Influences diabetes Susceptibility Despite Biallelic Expression of the Insulin Gene in Human Pancreas
- Biosynthesis of peptide hormones derived from precursor sequences
- The effects of vanadium treatment on bone in diabetic and non-diabetic rats
- Both TH1 and TH2 Cytokine mRNAs are Expressed in the NOD Mouse Pancreas in vivo
- Evidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6
- DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes
- Osteopontin deficiency impacts the pancreatic TH1/TH2 cytokine profile following multiple low dose streptozotocin-induced diabetes
- Early changes with diabetes in renal medullary hemodynamics as evaluated by fiberoptic probes and BOLD magnetic resonance imaging
- diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes
- Distinct regulation of autoreactive CD4 T cell expansion by interleukin‐4 under conditions of lymphopenia
- Characteristics of Rat CD4+CD25+ T Cells and Their Ability to Prevent Not Only diabetes But Also Insulitis in an Adoptive Transfer Model in BB Rats
- Novel genes identified by manual annotation and microarray expression analysis in the pancreas
- Evaluation of [18F]Fluoro-l-DOPA Positron Emission Tomography-Computed Tomography for Surgery in Focal Congenital Hyperinsulinism
- Insulin-like growth factor binding protein-3 is a novel mediator of apoptosis in insulin-secreting cells
- Differential contributions of APC subsets to T cell activation in nonobese diabetic mice
- Effect of 5-α dihydrotestosterone on T-cell proliferation of the female nonobese diabetic mouse
- Antigen-specific therapy for autoimmune disease: prospects for the prevention of insulin-dependent diabetes
- α-glucosidase inhibition and glucose-uptake stimulation by ethanol extracts from edible mushroom Hinmogi (Tremella fuciformis)
- The role of environmental factors in modulating insulin dependent diabetes
- Elevated NF-κB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function
- Preserved pulsatile insulin release from prediabetic mouse islets
- Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice
- Interaction of genetic and environmental factors in the pathogenesis of insulin-dependent diabetes mellitus
- Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin
- Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand
- Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known
- Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro
- Identification of a key protein associated with cerebral ischemia
- TNF-α mediated modulation of T cell development and exacerbation of in vitro T1DM in fetal thymus organ culture
- Glucose-induced release of nitric oxide from mouse pancreatic islets as detected with nitric oxide-selective glass microelectrodes
- Schistosoma mansoni and α-galactosylceramide: prophylactic effect of Th1 immune suppression in a mouse model of Graves’ hyperthyroidism
- Monoclonal (auto) antibodies in insulin-dependent diabetes mellitus
- E2f1 mutation induces early onset of diabetes and Sjogren’s syndrome in nonobese diabetic mice
- Down-regulation of Th1 mediated autoimmune pathology
- Antibodies to new beta cell antigen ICA12 in Latvian diabetes patients
- Inflammatory rather than infectious insults play a role in exocrine tissue damage in a mouse model for coxsackievirus B4‐induced pancreatitis
- Enhanced proinflammatory response to endotoxin after priming of macrophages with lead ions
- Activation of the intrinsic cell death pathway, increased apoptosis and modulation of astrocytes in the cerebellum of diabetic rats
- Role of IP-10/CXCL10 in the progression of pancreatitis-like injury in mice after murine retroviral infection
- The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking
- The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas
- Similar Peptides from Two β Cell Autoantigens, Proinsulin and Glutamic Acid Decarboxylase, Stimulate T Cells of Individuals at Risk for Insulin-Dependent …
- Recruitment and activation of naive T cells in the islets by lymphotoxin β receptor-dependent tertiary lymphoid structure
- Infections and autoimmunity: a panorama
- Autoimmune Epilepsy
- Glutamic acid decarboxylase autoantibodies in stiff-man syndrome
- Mechanisms of hyperinsulinaemia in Child’s disease grade B liver cirrhosis investigated in free living conditions
- A critical role for lymphotoxin-β receptor in the development of diabetes in nonobese diabetic mice
- Peripheral antigen-expressing cells and autoimmunity
- MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity
- Metallothionein suppresses collagen-induced arthritis via induction of TGF-β and down-regulation of proinflammatory mediators
- In vivo treatment with a MHC class I-restricted blocking peptide can prevent virus-induced autoimmune diabetes
- Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator
- Genetics and autoimmunity: HLA and MHC genes
- Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein …
- GM-CSF-induced autoimmune gastritis in interferon α receptor deficient mice
- Hyperglycaemia and the very preterm baby
- Development of genetically engineered human intestinal cells for regulated insulin secretion using rAAV-mediated gene transfer
- Notch3 and pTα/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells
- Adenovirus-mediated transfer of a modified human proinsulin gene reverses hyperglycemia in diabetic mice
- Cytokine-based immunointervention in the treatment of autoimmune diseases
- Effects of hyperglycemia on the modulation of vascular function by perivascular adipose tissue
- PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21)
- NOD. c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis
- Individuals from multiplex insulin-dependent diabetes mellitus (IDDM) families express higher levels of TCRBV2S1 than controls
- Suppression of insulitis and diabetes in B cell-deficient mice treated with streptozocin: B cells are essential for the TCR clonotype spreading of islet-infiltrating T cells
- Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease
- Role of regulatory T cells in the pathogenesis of autoimmune diabetes
- Pivotal roles of CD8+ T cells restricted by MHC class I–like molecules in autoimmune diseases
- Gene expression analysis reveals novel functions of vitamin D and glucocorticoids
- Regulation of inflammation in Th1 CD4 T cell mediated autoimmune responses
- Does O-GlcNAc play a role in neurodegenerative diseases?
- The design and construction of a scanning photo-acoustic calorimeter
- TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation
- αL-Integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium
- Functional Genetic Variations in Cytotoxic T-Lymphocyte Antigen 4 and Susceptibility to Multiple Types of Cancer
- Antigen Presentation, Dendritic Cells, and Autoimmunity
- Glutamic acid decarboxylase 65 and 67 isoforms in fetal, neonatal and adult porcine islets: predominant beta cell co-localization by light and confocal microscopy
- An indirect competitive immunoassay for insulin autoantibodies based on surface plasmon resonance
- A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice
- High T cell responses to the glutamic acid decarboxylase (GAD) isoform 67 reflect a hyperimmune state that precedes the onset of insulin-dependent diabetes
- It’stheecology, stupid!
- Glutamic acid decarboxylase autoantibodies in controlled and uncontrolled epilepsy: a pilot study
- Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in …
- Expression profile of MODY3/HNF-1α protein in the developing mouse pancreas
- Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
- Expression of the human insulin gene in the gastric G cells of transgenic mice
- Decreased basal non-insulin-stimulated glucose uptake by diaphragm in streptozotocin-induced diabetic mice infected with Schistosoma mansoni
- Gene fragment polymerization gives increased yields of recombinant human proinsulin C-peptide
- Autoimmunity during thymectomy-induced lymphopenia: role of thymus ablation and initial effector T cell activation timing in nonobese diabetic mice
- Amino acid-modified calcitonin immunization induces tumor epitope-specific immunity in a transgenic mouse model for medullary thyroid carcinoma
- KRJ-I and BON cell lines: defining an appropriate enterochromaffin cell neuroendocrine tumor model
- Autoimmunity: Thoughts for the millenium
- Apoptosis and remodelling of beta cells by paracrine interferon-γ without insulitis in transgenic mice
- Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat
- Lacritin and other new proteins of the lacrimal functional unit
- Control of cellular GADD34 levels by the 26S proteasome
- Permanent neonatal diabetes mellitus: clinical presentation and epidemiology in Oman
- Bone marrow precursors of nonobese diabetic mice develop into defective macrophage-like dendritic cells in vitro
- Humoral and cellular immune parameters before and during immunosuppressive therapy of a patient with stiff-man syndrome and insulin dependent diabetes mellitus
- Unravelling autoimmune pathogenesis by screening random peptide libraries with human sera
- Peptide dose, MHC affinity, and target self-antigen expression are critical for effective immunotherapy of nonobese diabetic mouse prediabetes
- Determination of glutamic acid decarboxylase 65 peptides presented by the type I diabetes-associated HLA-DQ8 class II molecule identifies an immunogenic peptide …
- Activin signaling: effects on body composition and mitochondrial energy metabolism
- Stimulating effect of bovine lactoferrin (bLF) on the level of lipopolisaccharide-binding protein (LBP) during experimental diabetes in mice
- Cytokine and cytokine receptor genes in the susceptibility and resistance to organ-specific autoimmune diseases
- Altered glucose homeostasis and oxidative impairment in pancreas of rats subjected to dimethoate intoxication
- Sub-clinical enterovirus infections in Norwegian infants: A prospective cohort study on viral circulation and predictors of infection
- MILD FORM OF INSULIN-RESISTANT NON-OBESE NIDDM OR IGT OF CHILDHOOD-ONSET
- Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus
- B cell–deficient NOD.H-2h4 mice have CD4+CD25+ T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis
- Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes
- Effects of prolonged exposure in vitro to interferon-γ and tumour necrosis factor-α on nitric oxide and insulin production of rat pancreatic islets
- Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen
- Gender difference in the glucagon response to glucopenic stress in mice
- Expression of glutamic acid decarboxylase (GAD) and its role as an autoantigen in insulin-dependent diabetes
- Innate Regulatory iNKT Cells
- Characterization of human AIRE promoter and analysis of AIRE expression in monocyte-derived dendritic cells and thymomas
- The role of coxsackie B viruses in the pathogenesis of type I diabetes
- Changing patterns of self-management in youth with type I diabetes
- Effect of maternal triglycerides and free fatty acids on placental LPL in cultured primary trophoblast cells and in a case of maternal LPL deficiency
- Production and purification of recombinant mouse cathepsin S
- The enhancement of the hyperglycemic effect of S-nitrosoglutathione and S-nitroso-N-acetylpenicillamine by vitamin C in an animal model
- Islet inflammation during initiation of type I diabetes: Virus infection and the role of cytokines in gene expression and β-cell death
- Role of Pathogenic Mediators in murine Arthritis and Levels of Serum Soluble CD21 and CD23 in autoimmune patients
- Genetic screening of infertile men
- Peptides presented in vivo by HLA-DR in thyroid autoimmunity
- The interface between innate and acquired immunity
- Effects of intensity of acute-resistance exercise on rates of protein synthesis in moderately diabetic rats
- PROPERTIES, FUNCTIONS AND BIOLOGICAL SIGNIFICANCE OF T LYMPHOCYTE SUBSETS
- Shared gene expression profiles in individuals with autoimmune disease and unaffected first-degree relatives of individuals with autoimmune disease
- Monogenic model for autoimmune diseases: molecular basis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
- Progress in virus research
- The Physiological Function of Endothelin-2 in Mice
- Derivation of a bisphenol A oral reference dose (RfD) and drinking-water equivalent concentration
- SUMO proteases: redox regulation and biological consequences
- The microRNA-21− PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death
- Mulberry fruit extract protects pancreatic β-cells against hydrogen peroxide-induced apoptosis via antioxidative activity
- PTPN2, a Candidate Gene for Type 1 diabetes, Modulates pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
- MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA
- Phagocytosis of enterovirus-infected pancreatic β-cells triggers innate immune responses in human dendritic cells
- Quantification and three-dimensional imaging of the insulitis-induced destruction of β-cells in murine type 1 diabetes
- Butein from Rhus verniciflua protects pancreatic β cells against cytokine-induced toxicity mediated by inhibition of nitric oxide formation
- Constitutive and inflammatory immunopeptidome of pancreatic β-cells
- Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes
- STAT1 is a master regulator of pancreatic β-cell apoptosis and islet inflammation
- Diagnosis of fulminant type 1 diabetes mellitus in an autopsy case with postmortem changes
- Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes
- mt-Nd2a Modifies Resistance Against Autoimmune Type 1 diabetes in NOD Mice at the Level of the pancreatic β-Cell
- The histopathologic effects of Morus alba leaf extract on the pancreas of diabetic rats
- Mechanisms in endocrinology: insulin and type 1 diabetes: immune connections
- Enteroviruses as causative agents in type 1 diabetes: loose ends or lost cause?
- Investigation of antidiabetic action of Antidesma bunius extract in type 1 diabetes
- Advances in our understanding of the pathophysiology of type 1 diabetes: lessons from the NOD mouse
- Primary prevention for type 1 diabetes mellitus?
- In vitro callus and in vivo leaf extract of Gymnema sylvestre stimulate β-cells regeneration and anti-diabetic activity in Wistar rats
- Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope
- Generation of functional insulin-producing cells in the gut by Foxo1 ablation
- Virus infections: lessons from pancreas histology
- Polymorphisms in the TLR3 gene are associated with risk for type 1 diabetes mellitus
- Type 1 diabetes vaccine development: Animal models vs. humans
- Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised …
- ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes
- Biochemical evaluation of oxidative stress in type 1 diabetes
- Persistence of prolonged C-peptide production in type 1 diabetes as measured with an ultrasensitive C-peptide assay
- … in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells
- TCR bias of in vivo expanded T cells in pancreatic islets and spleen at the onset in human type 1 diabetes
- Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling …
- CD4+ type II NKT cells mediate ICOS and programmed death-1–dependent regulation of type 1 diabetes
- Enteroviral pathogenesis of type 1 diabetes: queries and answers
- Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice
- The protective effect of testosterone on streptozotocin-induced apoptosis in β cells is sex specific
- Type 1 diabetes mellitus and hyperadrenocorticism in a ferret
- Dendritic cell-directed CTLA-4 engagement during pancreatic β cell antigen presentation delays type 1 diabetes
- Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice
- Effect of combined leaf extracts of Vernonia amygdalina (bitter leaf) and Gongronema latifolium (utazi) on the pancreatic [beta]-cells of streptozotocin-induced …
- Cutting edge: merocytic dendritic cells break T cell tolerance to β cell antigens in nonobese diabetic mouse diabetes
- Increased vulnerability to β-cell destruction and diabetes in mice lacking NAD (P) H: quinone oxidoreductase 1
- Differential responses of pancreatic β-cells to ROS and RNS
- Modulation of autoimmune diabetes by antibodies specific for N-acetyl-D-glucosamine (P4026)
- Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy
- Small-molecule inducer of β cell proliferation identified by high-throughput screening
- Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation
- Innate cell crosstalk in T1DM
- PTPN2 restrains CD8+ T cell responses after antigen cross-presentation for the maintenance of peripheral tolerance in mice
- Virus infections and type 1 diabetes risk
- Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells
- Alterations in glucose homeostasis in a murine model of Chagas disease
- … the clinic review series; focus on type 1 diabetes and viruses: role of antibodies enhancing the infection with Coxsackievirus-B in the pathogenesis of type 1 diabetes
- Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 diabetes
- Environmental trigger (s) of type 1 diabetes: why so difficult to identify?
- What is the key environmental trigger in type 1 diabetes—is it viruses, or wheat gluten, or both?
- Overexpression of β-catenin in dendritic cells from type 1 diabetes patients and NOD mice may drive induction of T cells involved in β-cells destruction (123.34)
- Promoting pancreatic Cell Proliferation
- Thalidomide attenuates multiple low-dose streptozotocin-induced diabetes in mice by inhibition of proinflammatory cytokines
- Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?
- Differences in the humoral autoreactivity to zinc transporter 8 between childhood-and adult-onset type 1 diabetes in Japanese patients
- Viral infections and diabetes
- Hypoglycemic, hepatoprotective and nephroprotective effects of methanolic leaf extract of Heinsia crinita (Rubiaceae) in alloxan-induced diabetic albino Wistar …
- Lower serum 25 (OH) D concentrations in type 1 diabetes: a meta-analysis
- Treating type-1 diabetes with an epigenetic drug
- Altered expression of nerve growth factor and its receptors in the kidneys of diabetic rats
- Fulminant type 1 diabetes mellitus
- Virus-induced models for type 1 diabetes in mice
- Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a “humanized” transgenic mouse model of type 1 diabetes
- Immune therapy in type 1 diabetes mellitus
- Developing a vaccine for type 1 diabetes through targeting enteroviral infections
- … mutations E6 27X and I923V of IFIH1 are associated with lower poly (I: C)–induced interferon-β production in peripheral blood mononuclear cells of type 1 diabetes …
- Diminished adenosine A1 receptor expression in pancreatic α-cells may contribute to the pathology of type 1 diabetes
- MIF contributes to Type 1 diabetes favors insulitis by mediating macrophages and dendritic cells maturation (P4533)
- Amelioration of streptozotocin-induced diabetes by Agrocybe chaxingu polysaccharide
- Novel SIRT1 mutation linked to autoimmune diabetes in humans
- Ablation of Rnf213 retards progression of diabetes in the Akita mouse
- Early suppression of immune response pathways characterizes children with prediabetes in genome-wide gene expression profiling
- Do viral infections protect from or enhance type 1 diabetes and how can we tell the difference?
- Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response
- Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial
- B cell-directed therapies in type 1 diabetes
- Assessment of the antidiabetic and antilipidemic properties of Bacillus subtilis SPB1 biosurfactant in alloxan‐induced diabetic rats
- Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα
- IL-21 promotes CD8+ CTL activity via the transcription factor T-bet
- IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
- Nickel (II) induced JNK activation-regulated mitochondria-dependent apoptotic pathway leading to cultured rat pancreatic β-cell death
- Mathematical modelling of immune regulation of type 1 diabetes
- Early determinants of type 1 diabetes: experience from the BABYDIAB and BABYDIET studies
- Re-evaluating gut insulin instinct
- Type 1 diabetes is associated with enterovirus infection in gut mucosa
- Characterization of membrane-shed microvesicles from cytokine-stimulated β-cells using proteomics strategies
- An AP-3-dependent mechanism drives synaptic-like microvesicle biogenesis in pancreatic islet β-cells
- High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition
- CASE STUDY 9 The young person with type 1 diabetes mellitus
- Mast cells control insulitis and increase Treg cells to confer protection against STZ‐induced type 1 diabetes in mice
- Nitric oxide is a mediator of antiproliferative effects induced by proinflammatory cytokines on pancreatic beta cells
- Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes
- Effect of Nigella sativa on pancreatic β-cell damage in streptozotocin-induced diabetic rats: histological and immunohistochemical study
- Immunomodulatory and antidiabetic effects of a new herbal preparation (HemoHIM) on streptozotocin-induced diabetic mice
- Autoreactive T cell trafficking into pancreatic islets during type 1 diabetes is more permissive as infiltration increases and requires CD11c+ APCs.(CAM4P. 153)
- Lack of association of IL-6 polymorphism with rheumatoid arthritis/type 1 diabetes: a meta-analysis
- Infant feeding and timing of complementary foods in the development of type 1 diabetes
- Interleukin-35 administration counteracts established murine type 1 diabetes–possible involvement of regulatory T cells
- Persistent C-peptide: what does it mean?
- Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice
- Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells
- Zn (II) ions co-secreted with insulin suppress inherent amyloidogenic properties of monomeric insulin
- Lactobacillus plantarum TN627 significantly reduces complications of alloxan-induced diabetes in rats
- Protection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin …
- Interaction of Nck1 and PERK phosphorylated at Y561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content
- Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice
- Activation of peritoneal macrophages during the evolution of type 1 diabetes (insulitis) in streptozotocin-treated mice
- Low frequency of regulatory T cells in the peripheral blood of children with type 1 diabetes diagnosed under the age of five
- Hyaluronic Acid Target Receptors (CD44 and RHAMM) involved in treatment of type 1 diabetes
- A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes
- Catenarin prevents type 1 diabetes in nonobese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways
- Polymeric delivery of therapeutic RAE-1 plasmid to the pancreatic islets for the prevention of type 1 diabetes
- Aqueous bark extract of cinnamomum zeylanicum: a potential therapeutic agent for streptozotocin-induced type 1 diabetes mellitus (T1DM) rats
- Persian Shallot (Allium hirtifolium Boiss) Extract Elevates Glucokinase (GCK) Activity and Gene Expression in Diabetic Rats
- … Insulitis In aly/aly MaleMice as an Animal Model of Autoimmune Pancreatitis: Activation of CD11c+, CD4+, and Th2 Cells and Predominant Destruction of β-cells
- Increased blood levels of growth factors, proinflammatory cytokines, and Th17 cytokines in patients with newly diagnosed type 1 diabetes
- In vivo imaging of GLP-1R with a targeted bimodal PET/fluorescence imaging agent
- Novel diagnostic and therapeutic approaches for autoimmune diabetes—a prime time to treat insulitis as a disease
- Microbes and Type 1 diabetes
- Selecting probiotics with the abilities of enhancing GLP-1 to mitigate the progression of type 1 diabetes in vitro and in vivo
- Evaluation of antidiabetic antihyperlipidemic and pancreatic regeneration, potential of aerial parts of Clitoria ternatea
- Role of topology in complex functional networks of beta cells
- Increased T cell proliferative responses to islet antigens identify clinical responders to anti-CD20 monoclonal antibody (rituximab) therapy in type 1 diabetes
- E2-2 dependent plasmacytoid dendritic cells control autoimmune diabetes
- Genetics of the HLA region in the prediction of type 1 diabetes
- Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6-and IL-10-independent …
- Infant and childhood diet and type 1 diabetes risk: recent advances and prospects
- The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes
- cDNA cloning and mRNA expression of canine pancreatic and duodenum homeobox 1 (Pdx-1)
- Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection
- Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetes
- Immunohistochemical analysis of IA-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells
- MAKING THE PAPER
- Small-molecule inhibitors of cytokine-mediated STAT1 signal transduction in β-cells with improved aqueous solubility
- Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells
- Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?
- Generation of transgenic fibroblasts expressing pancreas‑specific and doxycycline-inducible ICER Iγ for the establishment of a porcine model of human …
- Evaluation of antidiabetic activity of polysaccharide isolated from Phellinus linteus in non-obese diabetic mouse
- Partial ablation of leptin signaling in mouse pancreatic α-cells does not alter either glucose or lipid homeostasis
- Evaluation of the hypoglycemic effect of aqueous extract of Phyllanthus amarus in alloxan-induced diabetic albino rats
- PD‐L1 gene polymorphisms and low serum level of PD‐L1 protein are associated to type 1 diabetes in Chile
- The Potential of Jamur Dewa (Agaricusblazei Murril) Extract to Decrease Blood Glucose Diabetic Mice (Mus musculus)
- Detecting early-warning signals of type 1 diabetes and its leading biomolecular networks by dynamical network biomarkers
- The Roles of Iddm30 and Iddm24 in the Immunopathogenesis of Type 1 diabetes in BioBreeding Rats
- Insulin-secretagogue, antihyperlipidemic and other protective effects of gallic acid isolated from Terminalia bellerica Roxb. in streptozotocin-induced diabetic rats
- Intra-arterial targeted islet-specific expression of Sirt1 protects β cells from streptozotocin-induced apoptosis in mice
- Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetes
- Association investigation of BACH2 rs3757247 and SOD2 rs4880 polymorphisms with the type 1 diabetes and diabetes long-term complications risk in the …
- Eosinophils from patients with type 1 diabetes mellitus express high level of myeloid alpha-defensins and myeloperoxidase
- Osteoprotegerin and denosumab stimulate human beta cell proliferation through inhibition of the receptor activator of NF-κB ligand pathway
- ERα signalling drives β-cell formation and replication
- Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects
- D-saccharic acid-1, 4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic beta-cells from apoptosis via …
- Non-viral systemic delivery of Fas siRNA suppresses cyclophosphamide-induced diabetes in NOD mice
- Immunomodulatory effect of leaf extract of Murraya koenigii in diabetic mice
- Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes
- Transthyretin binds to glucose-regulated proteins and is subjected to endocytosis by the pancreatic β-cell
- HPTLC/HPLC and gravimetric methodology for the identification and quantification of gymnemic acid from Gymnema sylvestre methanolic extracts
- Meta-analysis of STAT4 and IFIH1 polymorphisms in type 1 diabetes mellitus patients with autoimmune polyglandular syndrome type III
- Genetically engineered Lactobacilli reprogram intestinal cells to secrete insulin and ameliorate hyperglycaemia
- Kin of IRRE-like protein 2 is a phosphorylated glycoprotein that regulates basal insulin secretion
- Deficiency in type I interferon signaling prevents the early inteferon-gene signature in pancreatic islets but not type 1 diabetes in non-obese diabetic mice
- Association of major histocompatibility complex class 1 chain-related gene a dimorphism with type 1 diabetes and latent autoimmune diabetes in adults in the Algerian …
- Helminth mediated modulation of Type 1 diabetes (T1D)
- Asian Journal of Biological and Life Sciences Original Research
- Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats
- pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells
- Tc17 CD8+ T cells potentiate Th1-mediated autoimmune diabetes in a mouse model
- … measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes …
- Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes …
- Research Article Catenarin Prevents Type 1 diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK …
- Anti-Saccharomyces cerevisiae Antibodies are Frequent in Type 1 diabetes
- Enterovirus RNA in blood is linked to the development of type 1 diabetes
- Genetic-induced variations in the GAD65 T-cell repertoire governs efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1 diabetes
- Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of diabetes in NOD Mice
- Inorganic nitrite stimulates pancreatic islet blood flow and insulin secretion
- Animals models for studying diabetes mellitus
- New insulin analogues and perioperative care of patients with type 1 diabetes
- Changes of the expressions of multiple metabolism genes in rat pancreatic islets after ventromedial hypothalamic lesioning
- From Toll-like receptors to the toll house of type 1 diabetes mellitus
- Identifying challenges of living with type 1 diabetes: child and youth perspectives
- The dual role of scavenger receptor class A in development of diabetes in autoimmune NOD mice
- Investigation of secreted protein transcripts as early biomarkers for type 1 diabetes in the mouse model
- Sudden death of a 15-year-old girl due to fulminant type 1 diabetes mellitus—Diabetic ketoacidosis induced cerebral edema?
- Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice
- Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes
- N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes
- Activated macrophages create lineage-specific microenvironments for pancreatic acinar-and β-cell regeneration in mice
- Peptide immunotherapies in Type 1 diabetes: lessons from animal models
- The role of interferon alpha in initiation of type I diabetes in the NOD mouse
- Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6. 2-mediated Th17 bias
- PTGS-2–PTGER2/4 Signaling Pathway Partially Protects From Diabetogenic Toxicity of Streptozotocin in Mice
- Regeneration of pancreatic b‑cells on streptozotocin induced diabetic rats under the effect of Swietenia macrophylla seeds
- Persistent infection of thymic epithelial cells with coxsackievirus B4 results in decreased expression of type 2 insulin-like growth factor
- Can we vaccinate against Type 1 diabetes?
- Type 1 diabetes therapy beyond T cell targeting: monocytes, B cells, and innate lymphocytes
- Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. fruit in streptozotocin induced diabetic rats
- Do β-cells generate peroxynitrite in response to cytokine treatment?
- Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes
- Morphological changes and Antihyperglycemic effect of M. champaca leaves extract on Beta-cell in alloxan induced diabetic rats
- Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves’ disease but not with rheumatoid arthritis in Russian population
- Articles in PresS. Am J Physiol Endocrinol Metab (January 28, 2014). doi: 10.1152/ajpendo. 00681.2013
- Early childhood infections and the risk of islet autoimmunity: the diabetes Autoimmunity Study in the Young (DAISY)
- Antidiabetic efficacy of bradykinin antagonist R-954 on glucose tolerance test in diabetic type 1 mice
- Imaging the pancreas: new aspects on lobular development and adult constitution
- CCR7 directs the recruitment of T cells into inflamed pancreatic islets of nonobese diabetic (NOD) mice
- Effects of Caffeic Acid Phenethyl Ester As anti-diabetic Therapy on Induced Immunoregulated Type 1 diabetes in Mice
- Historical perspective: beginnings of the β-cell: current perspectives in β-cell development
- Investigation of CTLA-4-318C/T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran
- Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development
- Study on genetic variance of miR-541 in type 1 diabetes
- 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: viruses, autoimmunity and immunoregulation
- Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice
- Discovery of Molecular Pathways Mediating 1,25-Dihydroxyvitamin D3 Protection Against Cytokine-Induced Inflammation and Damage of Human and Male Mouse …
- Enteroviruses, hygiene and type 1 diabetes: toward a preventive vaccine
- Fermented ginseng protects streptozotocin‐induced damage in rat pancreas by inhibiting nuclear factor‐κB
- Effect of chronic noise stress on serum glucose and lipids and morphology of Langerhans islets in neonatal rats
- Obestatin enhances in vitro generation of pancreatic islets through regulation of developmental pathways
- Rhinacanthus nasutus ameliorates cytosolic and mitochondrial enzyme levels in streptozotocin-induced diabetic rats
- Toll-like receptors and type 1 diabetes
- Immunotherapy for T1DM—targeting innate immunity
- Associations between two polymorphisms (FokI and BsmI) of vitamin D receptor gene and type 1 diabetes mellitus in Asian population: a meta-analysis
- Type 1 diabetes and gut microbiota: Friend or foe?
- Pathogenic and regulatory T cells in type 1 diabetes: losing self-control, restoring it, and how to take the temperature
- Is autoimmune diabetes caused by aberrant immune activity or defective suppression of physiological self-reactivity?
- Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in Akita diabetic mice and restores male fertility
- Increased GABAA channel subunits expression in CD8+ but not in CD4+ T cells in BB rats developing diabetes compared to their congenic littermates
- Proteomic analysis of plasma proteins in diabetic rats by 2D electrophoresis and MALDI-TOF-MS
- The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity
- Endocrine and metabolic aspects of the Wolfram syndrome
- Targeting CD44 augments the efficacy of Tregs in autoimmune diabetes
- Tolerance induction using Ag-ECDI-PLGA prevents autoimmunity in the BDC2. 5 AT model for T1D (P5208)
- Brugia malayi soluble and excretory‐secretory proteins attenuate development of streptozotocin‐induced type 1 diabetes in mice
- Molecular analysis of innate immunity in type 1 diabetes
- Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice
- IFN-γ induced by IL-12 administration prevents diabetes by inhibiting pathogenic IL-17 production in NOD mice
- Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice
- Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes
- RNase L contributes to experimentally induced type I diabetes onset in mice
- Research resource: dkCOIN, the National Institute of diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to …
- Thymic development of insulin reactive T cells (BA11P. 128)
- Transduced Tat-glyoxalase protein attenuates streptozotocin-induced diabetes in a mouse model
- Enhanced islet expansion by β‐cell proliferation in young diabetes‐prone rats fed a protective diet
- Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC
- Interferon and interferon‐inducible gene activation in patients with Type 1 diabetes
- Lactobacillus johnsonii N6.2 Mitigates the Development of Type 1 diabetes in BB-DP Rats
- TAP1 I333V gene polymorphism and type 1 diabetes mellitus: a meta‐analysis of 2248 cases
- Hypoglycemic effect of polysaccharides produced by submerged mycelial culture of Laetiporus sulphureus on streptozotocininduced diabetic rats
- On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes
- Oral ingestion of Capsaicin, the pungent component of chili pepper, enhances a discreet population of macrophages and confers protection from autoimmune …
- A distinct role of CD4+ Th17-and Th17-stimulated CD8+ CTL in the pathogenesis of type 1 diabetes and experimental autoimmune encephalomyelitis
- First presentation of diabetes as diabetic ketoacidosis in a case of Friedreich’s ataxia
- Milk A1 and A2 peptides and diabetes
- Plasma high sensitivity C-reactive protein and its relationship with cytokine levels in children with newly diagnosed type 1 diabetes and ketoacidosis
- Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+ CD25+ regulatory T cell function
- Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes
- A Distinct Role of CD4+ Th17- and Th17-Stimulated CD8+ CTL in the Pathogenesis of Type 1 diabetes and Experimental Autoimmune Encephalomyelitis
- Viral infection prevents diabetes by inducing regulatory T cells through NKT cell–plasmacytoid dendritic cell interplay
- Islet antigen-specific T cells and regulatory T cells in type 1 diabetes
- The role of IL-22 produced by Th17 cells in Type 1 diabetes
- IL-7 uniquely maintains Treg cells that reverse diabetes in NOD mice via integrin-β7-dependent localization (115.10)
- Autoimmune responses in T1DM: quantitative methods to understand onset, progression, and prevention of disease
- Hypoglycemic and antihyperglycemic effects of different extracts and combinations of Withania coagulans Dunal and Acacia arabica Lamk in Normal and …
- The interplay between the gut microbiota and the immune system in the mechanism of type 1 diabetes
- Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire
- Dynamic changes of the Th17/Tc17 and regulatory T cell populations interfere in the experimental autoimmune diabetes pathogenesis
- Multiple mechanisms involved in diabetes protection by lipopolysaccharide in non-obese diabetic mice
- Skeletal muscle contractile functions in streptozotocin induced type 1 diabetes mellitus
- In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts
- Unconventional recognition of peptides by T cells and the implications for autoimmunity
- Effects of physiological quercetin metabolites on interleukin-1β-induced inducible NOS expression
- Anti-diabetic activity of aqueous extract of Cochlospermum planchonii root in alloxan-induced diabetic rats
- Infant feeding in relation to islet autoimmunity and type 1 diabetes in genetically susceptible children: the MIDIA Study
- A novel concept for tolerization of diabetogenic CD4+ T cells by intranasal treatment with CTA1R7K-peptide-DD (THER6P. 859)
- Interleukin-18 promoter-607 C/A and-137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis
- Expression of Ins1 and Ins2 genes in mouse fetal liver
- Evaluation of antidiabetic and antioxidative effect of seed of Eeugenia jambolana in streptozotocin induced diabetic male rat
- Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells
- An islet-specific pulse of TGF-β abrogates CTL function and promotes β cell survival independent of Foxp3+ T cells
- Out of the F-box: reawakening the pancreas
- In vivo anti-hyperglycemic activity of saliva extract from the tropical leech Hirudinaria manillensis
- Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls
- Collection protocol for human pancreas
- Antibody-dependent enhancement of coxsackievirus-b infection: role in the pathogenesis of Type 1 diabetes
- Galectin-1 synthesis in type 1 diabetes by different immune cell types: Reduced synthesis by monocytes and Th1 cells
- The putative role of proteolytic pathways in the pathogenesis of Type 1 diabetes mellitus: the ‘autophagy’hypothesis
- A critical update on the immunopathogenesis of Stiff Person Syndrome
- ABOUT A PROPHYLAXIS AND TREATMENT OF TYPE 1 diabetes USING DOT METHOD
- IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in Chinese Han population
- Low‐cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C‐peptide
- TNF receptor 1 deficiency increases regulatory T cell function in nonobese diabetic mice
- Association of the interleukin‑18‑137 C/G,‑607 A/C polymorphisms with type 1 diabetes: A meta‑analysis
- Effect of CXCL10 receptor antagonist on islet cell apoptosis in a type I diabetes rat model
- Hygiene hypothesis and autoimmune diseases
- The role of synaptogenic synaptic adhesion molecules in insulin secretion
- The intestinal microbiome: relationship to type 1 diabetes
- Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: implications for diabetic intervertebral disc degeneration
- Functional specialization of islet dendritic cell subsets
- Antibodies recognizing specific Mycobacterium avium subsp. paratuberculosis’s MAP3738c protein in type 1 diabetes mellitus children are associated with serum Th1 …
- Ethanolic leaf extract of Vernonia amygdalina improves islet morphology and upregulates pancreatic G6PDH activity in streptozotocin-induced diabetic Wistar …
- Novel biomarkers in type 1 diabetes
- Antidiabetic potential of salvianolic acid B in multiple low-dose streptozotocin-induced diabetes
- PD‐L1 blockade overrides Salmonella typhimurium‐mediated diabetes prevention in NOD mice: No role for Tregs
- Anti-diabetic actions of carbon monoxide-releasing molecule (CORM)-A1: Immunomodulation and regeneration of islet beta cells
- Differentiation potential of mouse embryonic stem cells into insulin producing cells in pancreatic islet microenvironment
- Enhanced insulin clearance in mice lacking TRPM8 channels
- Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment
- Regulation of type 1 diabetes, tuberculosis, and asthma by parasites
- Bacille Calmette–Guérin/DNAhsp65 prime-boost is protective against diabetes in non-obese diabetic mice but not in the streptozotocin model of type 1 diabetes
- Early milestones in glucagon research
- Recognition of Ii-Key/MHC class II epitope hybrids derived from proinsulin and GAD peptides by T cells in type 1 diabetes
- A single base-pair deletion in the WFS1 gene causes Wolfram syndrome
- Antidiabetic activity of alcoholic stem extract of Gymnema montanum in streptozotocin-induced diabetic rats
- Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic …
- A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice
- The H1-receptor antagonist Cetirizine protects partially against cytokine-and hydrogen peroxide–induced β-TC6 cell death in vitro
- β‐Casomorphin‐7 Cause Decreasing in Oxidative Stress and Inhibiting NF‐κB‐iNOS‐NO Signal Pathway in Pancreas of diabetes Rats
- Distribution of C-peptide and its determinants in North American children at risk for type 1 diabetes
- Interrelationships between the pancreas and the thyroid
- NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes
- Cyclic GMP kinase I modulates glucagon release from pancreatic α-cells
- Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats
- Successful subcutaneous glucagon use for persistent hypoglycaemia in congenital hyperinsulinism
- Autoantibodies and high-risk HLA susceptibility markers in first-degree relatives of Brazilian patients with type 1 diabetes mellitus: a progression to disease based …
- Hypoglycemic activity and potential mechanism of a polysaccharide from the loach in streptozotocin-induced diabetic mice
- … insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas
- An innate triple hit initiates diabetes
- Type 1 diabetes mellitus in a patient with homozygous sickle cell anemia
- Blockade but Not Overexpression of the Junctional Adhesion Molecule C Influences
- Parp1 deficient mice are protected from streptozotocin-induced diabetes but not caerulein-induced pancreatitis, independent of the induction of Reg family genes
- pancreatic duodenal homeobox 1 protein is a novel β-cell-specific autoantigen for type I diabetes
- Case-control analysis of the ERAP1 polymorphism rs30187 in Italian type 1 diabetes mellitus patients
- Relationship between vitamin D during perinatal development and health
- Ptpn22 silencing in the NOD model of type 1 diabetes indicates the human susceptibility allele of PTPN22 is a gain-of-function variant
- B‐1 cells produce insulin and abrogate experimental streptozotocin‐induced diabetes
- NOX2 deficiency protects against streptozotocin-induced β-cell destruction and development of diabetes in mice
- MDA5 and MAVS mediate type I interferon responses to coxsackie B virus
- Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients
- Antibiotics in early life alter the gut microbiome and increase disease incidence in a spontaneous mouse model of autoimmune insulin-dependent diabetes
- Improvement of biochemical parameters in type 1 diabetic rats after the roots aqueous extract of yacon [Smallanthus sonchifolius (Poepp. & Endl.)] treatment
- CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L
- Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope
- Immunomodulatory effects of environmental endocrine disrupting chemicals
- Idd9.1 Locus Controls the Suppressive Activity of FoxP3+CD4+CD25+ Regulatory T-Cells
- Pam3CSK4 enhanced beta cell loss and diabetogenesis: the roles of IFN-gamma and IL-17
- Role of the phospatase LYP in T cell fuction: clinical, molecular and immunological correlates in a cohort of children affected by type 1 diabetes
- The vitamin D system is deregulated in pancreatic diseases
- T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses
- Activating natural cytotoxicity receptors of natural killer cells in cancer and infection
- Open Access Scientific Reports
- Thymoquinone enhances the activities of enzymes related to energy metabolism in peripheral leukocytes of diabetic rats
- Differential effects of HNF-1α mutations associated with familial young-onset diabetes on target gene regulation
- Serum metabolite signature predicts the acute onset of diabetes in spontaneously diabetic congenic BB rats
- α-Galactosylceramide ameliorates autoimmune diabetes in non-obese diabetic mice through a suppressive effect mediated by CD8+ T cells
- Impact of milk derived β-casomorphins on physiological functions and trends in research: a review
- Isolation of antidiabetic principle from fruit rinds of Punica granatum
- Helminth infections: therapeutic potential in autoimmune disorders
- Genome–virome interactions: examining the role of common viral infections in complex disease
- Epac is required for GLP-1R-mediated inhibition of oxidative stress and apoptosis in cardiomyocytes
- Secreted Proteins from the Helminth Fasciola hepatica Inhibit the Initiation of Autoreactive T Cell Responses and Prevent diabetes in the NOD Mouse
- Experimental encephalomyocarditis virus infection in small laboratory rodents
- Cerebrum malformation in offspring of diabetic mothers
- The levels of circulating TRAIL at the onset of type 1 diabetes are markedly decreased in patients with ketoacidosis and with the highest insulin requirement
- Gut-pancreatic axis AMPlified in islets of langerhans
- Peripherin-reactive antibodies in mouse, rabbit, and human blood
- A novel single nucleotide polymorphism in the protein tyrosine phosphatase N22 gene (PTPN22) is associated with Type 1 diabetes in a Chinese population
- Beyond HLA-A* 0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes
- Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets
- EFFECT of Aloe vera EXTRACT TO THE INSULIN-LIKE GROWTH FACTOR-1 (IGF-1) LEVELS FROM VISCERAL FAT TISSUE IN Rattus norvegicus WISTAR …
- Inference of gene networks from time series expression data and application to type 1 diabetes
- Cooperative ‘bots’ don’t need a boss
- Antigen recognition in the islets changes with progression of autoimmune islet infiltration
- Virus-Related diabetes in Cattle
- Anti-diabetic and haematological effects of n-butanol fraction of Alchornea cordifolia leaf extract in streptozotocin-induced diabetic wistar rats
- Epigallocatechin-3-gallate modulates anti-oxidant defense enzyme expression in murine submandibular and pancreatic exocrine gland cells and human HSG cells
- Synthesis of diosgenin-ibuprofen derivatives and their activities against insulin-dependent diabetes mellitus
- Genetic Testing of Newborns for Type 1 diabetes Susceptibility–The MIDIA Study
- Immunotargeting of insulin reactive CD8 T cells to prevent diabetes
- The protective effects of Ziziphus vulgaris L. fruits on biochemical and histological abnormalities induced by diabetes in rats
- Mitochondrial proteome analysis reveals depression of the Ndufs3 subunit and activity of complex I in diabetic rat brain
- Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice
- Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis
- Previous contact with Strongyloides venezuelensis contributed to prevent insulitis in MLD-STZ diabetes
- HLA-DR* 0401 expression in the NOD mice prevents the development of autoimmune diabetes by multiple alterations in the T-cell compartment
- Development of a multipurpose time-resolved fluorescence immunoassay for rat insulin
- Cardiac energy metabolism and oxidative stress biomarkers in diabetic rat treated with resveratrol
- Elevated IFN-alpha/beta levels in a streptozotocin-induced type I diabetic mouse model promote oxidative stress and mediate depletion of spleen-homing CD8+ T …
- Regenerating gene Iα is a biomarker for diagnosis and monitoring of celiac disease: a preliminary study
- Analysis of multifocal electroretinograms from a population with type 1 diabetes using partial least squares reveals spatial and temporal distribution of changes to …
- Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells
- Proinsulin multi-peptide immunotherapy induces antigen-specific regulatory T cells and limits autoimmunity in a humanized model
- The Perfect Storm?
- Anti-diabetic property and phytochemical composition of aqueous and methanol extracts of buchholzia coriacea seeds in alloxan-induced diabetic rats
- Antihyperglycemic and antioxidant activities of alcoholic extract of Commiphora mukul gum resin in streptozotocin induced diabetic rats
- Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice
- Zinc is the modulator of the calcium-dependent activation of post-translationally acting thiol-enzymes in autoimmune diseases
- Interindividual glucose dynamics in different frequency bands for online prediction of subcutaneous glucose concentration in type 1 diabetic subjects
- α4β7 integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice
- γδ T cells recognize the insulin B: 9–23 peptide antigen when it is dimerized through thiol oxidation
- NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis
- Optimal T-cell receptor affinity for inducing autoimmunity
- Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients
- Institutional Repository of Lund University
- The role of Coxsakie virus in the development of type i diabetes mellitus
- Clinical and genetic characteristics of patients with autoimmune thyroid disease with anti-islet autoimmunity
- Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes
- Chapter III. Re-establishing Tolerance
- pancreatic acinar-specific overexpression of Reg2 gene offered no protection against either experimental diabetes or pancreatitis in mice
- Death waits for no man–does it wait for a virus? How enteroviruses induce and control cell death
- T cell-driven initiation and propagation of autoimmune diabetes
- Type 1 diabetes mellitus in mice increases hippocampal D-serine in the acute phase after streptozotocin injection
- Contractile functions of slow and fast skeletal muscles in streptozotocin induced type 1 diabetic sprague dawley rats
- CCL22-producing CD8α− myeloid dendritic cells mediate regulatory T cell recruitment in response to G-CSF treatment
- The role of AIRE in human autoimmune disease
- Administration of a determinant of preproinsulin can induce regulatory T cells and suppress anti-islet autoimmunity in NOD mice
- Dose the C-Peptide Level Predict Remission Phase in Type 1 diabetes Mellitus Pediatric Patients Tawfeeq FR AL-Auqbi* Maan AJ Bahrani** Noor TT Al …
- Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model
- To B or not to B—pathogenic and regulatory B cells in autoimmune diabetes
- Distribution of insulin mRNA transcripts within the human body
- HSP65 serves as an immunogenic carrier for a diabetogenic peptide P277 inducing anti-inflammatory immune response in NOD mice by nasal administration
- Mathematical modeling of autoimmune disease
- 1H NMR-based Metabonomic Analysis of Metabolic Changes in Streptozotocin-induced Diabetic Rats
- Pharmacological evaluation of “Glyoherb”: A polyherbal formulation on streptozotocin-induced diabetic rats
- Biochemical evaluation of antidiabetic and antioxidant potentials of Annona squamosa leaves extracts studied in STZ induced diabetic rats
- Metabolic abnormalities in the pathogenesis of type 1 diabetes
- Glucagon responses of isolated a cells to glucose, insulin, somatostatin, and leptin
- Effect of red Hibiscus aqueous extract on alloxan-induced diabetes in adult male albino rats
- Oral Administration of Recombinant Lactococcus lactis Expressing HSP65 and Tandemly Repeated P277 Reduces the Incidence of Type I diabetes in Non …
- Investigation into mechanism of action of anti-diabetic activity of Emblica officinalis on streptozotocin induced type I diabetic rat
- DC-SIGN polymorphisms are associated to type 1 diabetes mellitus
- Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs
- Regulatory T cell phenotype and function 4 years after GAD–alum treatment in children with type 1 diabetes
- D-Saccharic acid 1, 4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and …
- Linoleic and alpha linolenic acids ameliorate streptozotocin-induced diabetes in mice
- Reduced deaf1 mRNA expression during STZ-induced diabetes mellitus inhibits foxp3+ regulatory T-cells differentiations in rat’ s pancreatic lymph nodes
- Anti-diabetic effects of red rose flowers in streptozotocin-induced diabetic mice
- Structural and functional characterization of a single-chain peptide–MHC molecule that modulates both naive and activated CD8+ T cells
- Role of thirst and visual barriers in the differential behavior displayed by streptozotocin-treated rats in the elevated plus-maze and the open field test
- Antidiabetic effect of Gymnema sylvestre in streptozotocin induced diabetes in rats
- … and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets
- Effect of Kombucha, a fermented black tea in attenuating oxidative stress mediated tissue damage in alloxan induced diabetic rats
- MCS-18, a novel natural plant product prevents autoimmune diabetes
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- Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapy
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- The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach
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- The IL-2 diphtheria toxin fusion protein denileukin diftitox modulates the onset of diabetes in female nonobese diabetic animals in a time-dependent manner and …
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- Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels
- Selective cognitive and psychiatric manifestations in Wolfram Syndrome
- Leptin deficiency causes insulin resistance induced by uncontrolled diabetes
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- Hypoglycaemic and anti-diabetic activity of stem bark extracts Erythrina indica in normal and alloxan-induced diabetic rats
- Antigen-dependent immunotherapy of non-obese diabetic mice with immature dendritic cells
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- Islet-associated T-cell receptor-β CDR sequence repertoire in prediabetic NOD mice reveals antigen-driven T-cell expansion and shared usage of VβJβ TCR chains
- Nkx2. 2 activates the ghrelin promoter in pancreatic islet cells
- Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma
- Identifying a Possible Link between Ectopic Germinal Centers and the Evolution of Type I diabetes
- Hagedorn Research Institute, Department of Beta-cell Regeneration, Gentofte, Denmark; 2 Novo Nordisk A/S, Department of Antibody Technology, Måløv …
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- Patient‐related risk factors for implant therapy. A critique of pertinent literature
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- Antagonistic Salubrious Effects of Macerated Allium Sativum (garlic) on Cytoarchitectural Alterations in the Pancreas of Alloxan Induced Diabetic Rats.
- Research Article Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum
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- Effect of Honey Bee Venom (Apis mellifera) on Hyperglycemia and Hyperlipidemia in Alloxan Induced Diabetic Rabbits. J diabetes Metab 6: 507. doi: 10.4172 …
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- Advances in Biomedicine and Pharmacy
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- The Impact of Microbiome Alterations in the NOD Mouse Model of Type 1 diabetes
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- Targeting of a T cell agonist peptide to lysosomes by DNA vaccination induces tolerance in the nonobese diabetic mouse
- Characterization of the antidiabetic role of Parkinsonia aculeata (Caesalpineaceae)
- Male and female NOD mice differentially express peroxisome proliferator-activated receptors and pathogenic cytokines
- Combined effect of hydrogen sulphide donor and losartan in experimental diabetic nephropathy in rats
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- Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim/Mcl-1 imbalance
- Effect of nicotinamide on amino acids content in bone collagen depending on biological availability of vitamins in diabetic rats
- Amadori-glycated phosphatidylethanolamine, a potential marker for hyperglycemia, in streptozotocin-induced diabetic rats
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- Antihyperglycemic, antihyperlipidemic, and renoprotective effects of Chlorella pyrenoidosa in diabetic rats exposed to cadmium
- Cognitive and developmental outcome of conservatively treated children with congenital hyperinsulinism
- The effect of methanolic extract of Otostegia persica on serum glucose level and renal function indicators in streptozotocin induced diabetic rats
- Results in Immunology
- The gut, immunoregulation and micro‐organisms from man’s evolutionary past
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- The hypoglycemic effect of the aqueous extract of the fruits of Balanites aegypticea in Alloxan-induced diabetic rats
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- Implementation of Novel Group Delay Decomposition Method and Surgical Protocol for Assessing Peripheral Neuropathy
- SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy
- A review on the formulation and analysis of anti-diabetic agent: gliclazide
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- Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection
- Perspectives of the relationship between IL-7 and autoimmune diseases
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- Ebselen reduces hyperglycemia temporarily-induced by diazinon: A compound with insulin-mimetic properties
- Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats
- Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients
- Ultra-structural changes in cells from the CNS in offspring from diabetic rats
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- Effects of insulin on CYP3A activity and nicardipine disposition in streptozotocin-induced diabetic rats
- Can we vaccinate against depression?
- Biomarkers for diagnosis and monitoring of celiac disease
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- Molecular analysis of persistent enterovirus infections.
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- Anti-diabetic effect of Cyclo-His-Pro (CHP)-enriched yeast hydrolysate in streptozotocin-induced diabetic mice
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- ANTIDIABETIC, ANTIATHEROSCLEROTIC AND HEPATOPROTECTIVE PROPERTIES OF DECALEPIS HAMILTONII IN STREPTOZOTOCIN‐INDUCED DIABETIC …
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- ARGENTINE SOCIETY OF BIOLOGY
- Study of T cell pathogenicity in central nervous system autoimmunity
- Novel vitamin D compounds and skin cancer prevention
- SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells
- Signaling Cross-Talk Regulating the Expression of Arginase 1 in Murine Macrophages
- Insights into the control of growth and axon guidance by the Drosophila insulin receptor
- Predictors of vitamin D status in New Zealand adults and the effect of vitamin D2 and vitamin D3 supplementation on 25-hydroxyvitamin D and parathyroid hormone …
- Identification of shared and distinct gene-disease associations among multiple related diseases and multiple subtypes of a disease
- Use of the 5′ untranslated region and VP1 region to examine the molecular diversity in enterovirus B species
- Neostigmine-induced contraction and nitric oxide-induced relaxation of isolated ileum from STZ diabetic guinea pigs
- Localisation of equilibrative nucleoside transporter 3 (ENT3) in mouse brain
- The role of GPR65 in T cell function and demyelinating autoimmune disease
- Characterization of mitochondrial membrane proteins as novel components in mitochondrial dynamics
- The role of the cytokines IL-17A and IL-33 in inflammatory arthritis and psoriasis
- Neonatal Hypoglycaemia
- Doing psychiatry wrong: A critical and prescriptive look at a faltering profession
- Expression of CD47 in the pancreatic β‐cells of people with recent‐onset type 1 diabetes varies according to disease endotype
- Potential Mimicry of Viral and pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 diabetes
- Persistence of coxsackievirus B4 in pancreatic β cells disturbs insulin maturation, pattern of cellular proteins, and DNA methylation
- Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion
- Formation of pancreatic β-cells from precursor cells contributes to the reversal of established type 1 diabetes
- Cyclin D3 promotes pancreatic β cell fitness and viability in a cell cycle
- eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 diabetes
- IFN-γ activated sites in the survivin gene promoter region: the point of no return of cytokine-induced pancreatic β-cells death?
- In vitro Analysis of Exocrine Pancreas Secretome on Islet Cell Phenotype–A Potential Therapy for Type 1 diabetes
- The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA
- Immune Modulation and Vascular Repair Sustain pancreatic Beta Cell Regeneration To Reverse Late Stage Type 1 diabetes
- Type 1 diabetes associated autoimmunity
- The decline in cancer incidence in patients with long-duration type 1 diabetes: what really happens over time?
- Grape seed proanthocyanidin extract and insulin prevents cognitive decline in type 1 diabetic rat by impacting Bcl-2 and Bax in the prefrontal cortex
- An overview of the epidemiology of type 1 diabetes mellitus
- CHOP deficiency ameliorates ERK5 inhibition-mediated exacerbation of streptozotocin-induced hyperglycemia and pancreatic β-Cell apoptosis
- Probiotics and prebiotics for the amelioration of type 1 diabetes: present and future perspectives
- Participation of Hsp70 and Hsp90α heat shock proteins in stress response in the course of type 1 diabetes mellitus
- GATA6 plays an important role in the induction of human definitive endoderm, development of the pancreas, and functionality of pancreatic β cells
- Retracted: Baicalin prevents tumor necrosis factor‐α−induced apoptosis and dysfunction of pancreatic β‐cell line Min6 via upregulation of miR‐205
- … Factor-Alpha (TNF-α) and Sperm Count Increase in Type 1 diabetes Mellitus Rat (Rattus norvegicus) Model with Turmeric Rhizome (Curcuma longa L) Extract
- Potentials of Aqueous Extract of Bambusa vulgaris to Reactivate β-cells of Pancreas in Alloxan-Induced Diabetic Wistar Rats
- A viral link for type 1 diabetes
- Post-translational modifications contribute to neoepitopes in Type-1 diabetes: Challenges for inducing antigen-specific tolerance
- Tetrahedral framework nucleic acids induce immune tolerance and prevent the onset of type 1 diabetes
- From insulin synthesis to secretion: Alternative splicing of type 2 ryanodine receptor gene is essential for insulin secretion in pancreatic β cells
- … the potential impact of post translational modification of auto-antigens by tissue transglutaminase on humoral islet autoimmunity in type 1 diabetes
- Prospective virome analyses in young children at increased genetic risk for type 1 diabetes
- Fulminant type 1 diabetes: 20 years of discovery and development
- Nanoceria suppresses multiple low doses of streptozotocin-induced Type 1 diabetes by inhibition of Nrf2/NF-κB pathway and reduction of apoptosis
- The role of coupling factors on the emergence of synchronization and chimera patterns in network of non-locally coupled pancreatic β-cells
- Control of TRPM3 ion channels by protein kinase Ck2-mediated phosphorylation in pancreatic β-cells of the line INS-1
- Generation of pancreatic β cells from CD177+ anterior definitive endoderm
- New-onset type 1 diabetes mellitus with diabetic ketoacidosis and pancreatitis in a patient with COVID-19
- A new therapeutic approach for type 1 diabetes: rationale for GNbAC1, an anti‐HERV‐W‐Env monoclonal antibody
- Tetrahedral framework nucleic acids reverse new-onset type 1 diabetes
- Do be so immature: dedifferentiated β cells help mice evade Type 1 diabetes
- Immunotherapy strategies for the prevention and treatment of distinct stages of type 1 diabetes: an overview
- Biomimetic carbon monoxide nanogenerator ameliorates streptozotocin induced type 1 diabetes in mice
- Leaf extract of Morinda lucida improves pancreatic beta-cell function in alloxan-induced diabetic rats
- Developing a vaccine for type 1 diabetes by targeting coxsackievirus B
- A zinc finger protein, Zfp444, is expressed in differentiating pancreatic β-cells and activates Glut2 gene expression
- A map of human type 1 diabetes progression by imaging mass cytometry
- Insulin‐producing cells derived from ‘induced pluripotent stem cells’ of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased …
- A Single L/D-Substitution at Q4 of the mInsA2-10 Epitope Prevents Type 1 diabetes in Humanized NOD Mice
- Effects of anti-CD20 monoclonal antibody and IL-10 on pancreatic β cell regeneration in nonobese diabetic mice
- Preventing type 1 diabetes in childhood
- On the role IL-4/IL-13 heteroreceptor plays in regulation of type 1 diabetes
- … and anti-inflammatory effects of Acrocarpus fraxinifolius on hyperglycemia, hyperlipidemia and liver/kidney dysfunctions against alloxan induced Type 1 diabetes in …
- An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes
- CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes
- Macrophage IFN-I signaling promotes autoreactive T cell infiltration into islets in type 1 diabetes model
- The ameliorative effect of bromelain on STZ-induced type 1 diabetes in rats through Oxi-LDL/LPA/LPAR1 pathway
- A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
- Antibodies against H1N1 influenza virus cross‐react with α‐cells of pancreatic islets
- Tetraspanin‐7 regulation of L‐type voltage‐dependent calcium channels controls pancreatic β‐cell insulin secretion
- IL-17F induces inflammation, dysfunction and cell death in mouse islets
- Artesunate prevents type 1 diabetes in NOD mice mainly by inducing protective IL‐4—producing T cells and regulatory T cells
- Role of pro-inflammatory cytokines and biochemical markers in the pathogenesis of type 1 diabetes: correlation with age and glycemic condition in diabetic …
- The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes
- The reconstructed natural history of type 1 diabetes mellitus
- Pathogenesis of Type 1 diabetes: Role of Dietary Factors
- Association Between Enterovirus Infection and Type 1 diabetes Risk: A Meta-Analysis of 38 Case-Control Studies
- Psychological stress and type 1 diabetes mellitus: what is the link?
- Tellurium compounds prevent and reverse type-1 diabetes in NOD mice by modulating α4β7 integrin activity, IL-1β, and T regulatory cells
- An Insulin‐Inspired Supramolecular Hydrogel for Prevention of Type 1 diabetes
- Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes
- BIOACTIVE CONSTITUENTS AND ANTIOXIDANT ACTIVITY OF POLYHERBAL ETHANOLIC EXTRACT IN STREPTOZOTOCIN INDUCED DIABETIC RATS
- Preventive effect of fermented brown rice and rice bran on spontaneous type 1 diabetes in NOD female mice
- Nitric oxide and antiviral defense in pancreatic β-cells: evidence for inhibition of mitochondrial oxidative metabolism as a novel antiviral mechanism
- P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice
- Acute pancreatitis may be a pathogenic factor of fulminant type 1 diabetes mellitus
- Resveratrol inhibits macrophage infiltration of pancreatic islets in streptozotocin-induced type 1 diabetic mice via attenuation of the CXCL16/NF-κΒ p65 signaling …
- Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
- Possible involvement of autoimmunity in fulminant type 1 diabetes
- The protective effects of human milk-derived peptides on the pancreatic islet biology
- Innate inflammation in type 1 diabetes
- Decrement in cellular iron and reactive oxygen species, and improvement of insulin secretion in a pancreatic cell line using green tea extract
- Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling
- A cell-based assay for the detection of pathogenic anti-voltage-gated calcium channel autoantibodies in immunoglobulin G from patients with type 1 diabetes
- Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, protects the pancreas from apoptosis and proliferation via oxidative stress in …
- Abnormalities in proinsulin processing in islets from individuals with longstanding T1D
- Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes
- Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes
- Localization of enteroviral RNA within the pancreas in donors with T1D and T1D-associated autoantibodies
- Examining the Co-localization and Distribution of Insulin Receptor on CD3 Cells in Type 1 Diabetic Human pancreatic Cadaver Samples
- The DNA sensor AIM2 protects against streptozotocin-induced type 1 diabetes by regulating intestinal homeostasis via the IL-18 pathway
- Tracking the antibody immunome in type 1 diabetes using protein arrays
- Effect of different cereal peptides on the development of type 1 diabetes is associated with their anti‐inflammatory ability: In vitro and in vivo studies
- Type 1 diabetes mellitus and enterovirus linkage: search for associated etiopathology
- Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function
- The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes
- 115-OR: Microbiome Antigens as a Vaccination Strategy in Type 1 diabetes
- Structural characters and protecting β-cells of a polysaccharide from flowers of Inula japonica
- Restoration of Insulin Productionin Induced Diabetic Rats, by Wakouba an Extract of Local Plant
- Partial remission in Brazilian children and adolescents with type 1 diabetes. Association with a haplotype of class II human leukocyte antigen and synthesis of …
- Curcumin alleviates liver oxidative stress in type 1 diabetic rats
- Oral Therapy with Colonization Factor Antigen I (CFA/I) Activates Stable Regulatory T Cells (Tregs) in the pancreatic Lymph Nodes (PaLNs) of Non-Obese Diabetic …
- The innate immune receptor MDA 5 limits rotavirus infection but promotes cell death and pancreatic inflammation
- Towards a coxsackievirus B-based vaccine to combat T1DM
- Metabolic abnormalities exacerbate Sjögren’s syndrome by and is associated with increased the population of interleukin–17–producing cells in NOD/ShiLtJ …
- No Compensatory Increase in Non-ß Hormone Expressing Cells in the pancreatic Duct Glands in Type 1 diabetes
- Proteomic and transcriptional profiles of human stem cell-derived β cells following enteroviral challenge
- Image-based machine learning algorithms for disease characterization in the human type 1 diabetes pancreas
- IL-17 in pancreatic disease: pathogenesis and pharmacotherapy
- Sex-dependent effects of bisphenol A on type 1 diabetes development in non-obese diabetic (NOD) mice
- In silico analysis reveals interrelation of enriched pathways and genes in type 1 diabetes
- Human herpesvirus-6 is present at higher levels in the pancreatic tissues of donors with type 1 diabetes
- The Effect of Immunosuppressive Adjuvant Kynurenine on Type 1 diabetes Vaccine
- Association between antioxidant enzyme activities and enterovirus-infected type 1 diabetic children
- Nerve growth factor receptor TrkA signaling in streptozotocin-induced type 1 diabetes rat brain
- Nitric oxide suppresses β-cell apoptosis by inhibiting the DNA damage response
- The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus
- Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
- Peptidome Analysis of pancreatic Tissue Derived from T1DM Mice: Insights into the Pathogenesis and Clinical Treatments of T1DM
- Glycated whey proteins protect NOD mice against type 1 diabetes by increasing anti-inflammatory responses and decreasing autoreactivity to self-antigens
- Celiac crisis in an adult type 1 diabetes mellitus patient presented with diarrhea, weight loss and hypoglycemic attacks
- Type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment
- T cells in type 1 diabetes: instructors, regulators and effectors: a comprehensive review
- CREM variant rs17583959 conferred susceptibility to T1D risk in the Tunisian families
- Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats
- Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies
- Specific inulin‐type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis
- β-cell dedifferentiation prior to insulitis prevents T1DM
- Laser capture microdissection tailored to type 1 diabetes mellitus research
- Cellular localisation of the kinin B1R in the pancreas of streptozotocin-treated rat and the anti-diabetic effect of the antagonist SSR240612
- Protection from vomiting and β-cell death
- The SARS‐CoV‐2 pandemic is associated with increased severity of presentation of childhood onset type 1 diabetes mellitus: A multi‐centre study of the first COVID …
- Systemic TNFα correlates with residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes
- Punica granatum L. Fruit aqueous extract suppresses reactive oxygen species-mediated p53/p65/miR-145 expressions followed by Elevated Levels of irs-1 in …
- Ketogenic diet for refractory epilepsy with MEHMO syndrome: caution for acute necrotizing pancreatitis
- Glucose‐lowering effect of Gryllus bimaculatus powder on streptozotocin‐induced diabetes through the AKT/mTOR pathway
- Reg3g overexpression promotes β cell regeneration and induces immune tolerance in nonobese‐diabetic mouse model
- The role of Sechium edule fruits ethanolic extract in insulin production and malondialdehyde level in stz-induced diabetic rat
- Children with type 1 diabetes of early age at onset–immune and metabolic phenotypes
- Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2
- Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from …
- Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice
- Engineering extracellular vesicles to target pancreatic tissue in vivo
- Assessing effector T cells in type 1 diabetes
- Biochemical and histopathological investigations of antidiabetic potential of polyherbal formulation in alloxan induced diabetic rats.
- Interference with pancreatic sympathetic signaling halts the onset of diabetes in mice
- Gut microbial metabolites alter IgA immunity in type 1 diabetes
- Bacteroidetes and Firmicutes levels in gut microbiota and effects of hosts TLR2/TLR4 gene expression levels in adult type 1 diabetes patients in Istanbul, Turkey
- Retracted: Bilobalide alleviates tumor necrosis factor‐alpha‐induced pancreatic beta‐cell MIN6 apoptosis and dysfunction through upregulation of miR‐153
- A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
- Biogenic integrated ZnO/Ag nanocomposite: Surface analysis and in vivo practices for the management of type 1 diabetes complications
- Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Prevent Transfer of Type 1 diabetes in NOD Mice by Expanding Foxp3+ Tregs
- Antidiabetic effects of aqueous extract of Baillonella toxisperma Pierre (Sapotacae) in streptozotocin-induced diabetic rats
- Population dynamics of MafA-positive cells during ontogeny of human pancreas
- Imaging the emergence and natural progression of spontaneous autoimmune diabetes
- Glis3 Regulates pancreatic ß-Cell Development in Part through Coordination with Other Islet Transcription Factors
- New-onset diabetes mellitus with COVID-19: Coincidence or cause
- Characterization of proinsulin T cell epitopes restricted by type 1 diabetes–associated HLA class II molecules
- Effectiveness of ethanolic extract Ketepeng cina leaves (Senna alata L.) as antidiabetic activity test in male Wistar rats induced by alloxan
- Th1 chemokines in autoimmune endocrine disorders
- Interleukin-33 prevents the development of autoimmune diabetes in NOD mice
- Oral probiotic promotes indoleamine 2, 3-dioxygenase-and TGF-β–Producing plasmacytoid dendritic cells to initiate protection against type 1 diabetes
- Green synthesis of gold nanoparticle using Eclipta alba and its antidiabetic activities through regulation of Bcl-2 expression in pancreatic cell line
- Self-renewing islet TCF1+ CD8 T cells undergo IL-27–controlled differentiation to become TCF1− terminal effectors during the progression of type 1 diabetes
- Down-regulation of microRNA-28 in peripheral blood mononuclear cell plays a role in pathogenesis of type 1 diabetes
- … a Strong Effect of HLA and Identifying Variants in CSAD/lnc-ITGB7-1 on Chromosome 12q13.13 Associated With Susceptibility to Fulminant Type 1 diabetes
- Antihyperglycemic and diabetic wound healing activity of smallanthus sonchifolius leaves extract
- Immune cell trafficking to the islets during type 1 diabetes
- … -α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes
- Evaluation for type 1 diabetes associated autoantibodies in diabetic and non-diabetic Australian terriers and Samoyeds
- Gestational diabetes promotes germ cell cCyst breakdown and primordial follicle formation in newborn mice via the AKT signaling pathway
- PROGRESSION OF AUTOANTIBODIES ANTI-GAD AND ANTI-IA2 IN TYPE 1A DIABETICS AGED OF 5 TO 21 YEARS IN CÔTE D’IVOIRE
- Higher abundance of enterovirus A species in the gut of children with islet autoimmunity
- Antibodies against H1N1 influenza virus hemagglutinin cross-react with prohibitin
- Protective effects of lyophilized ethanolic extract of Achillea arabica Kotschy. On the islet β cells of streptozotocin-induced diabetic rats
- The Aerobic Training and Berberine Chloride Intervention on pancreatic Tissue Antioxidant Enzymes and Lipid Peroxidation in Type 1 Diabetic Rats
- Signaling, stress response and apoptosis in pre-diabetes and diabetes: restoring immune balance in mice with alloxan-induced type 1 diabetes mellitus
- Biomedical Data Commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in Type 1 diabetes
- Chromatin loops and expression QTL colocalization reveal novel gene targets for T1D-associated GWAS variants in immune cells
- Formulation and evaluation of capsules and suppositories containing Gongrenema Latifolium
- Pancreas‐Specific Delivery of β‐Cell Proliferating Small Molecules
- Knowledge, attitudes and practices of school teachers regarding acute complications of type 1 diabetes mellitus in Abha city, southwestern Saudi Arabia.
- Comparative and correlative assessments of cytokine, complement and antibody patterns in paediatric type 1 diabetes
- Association of KIR gene polymorphisms with Type 1 diabetes: a meta-analysis
- MicroRNAs: Markers of β-cell stress and autoimmunity
- Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at …
- Anti-serum with anti-autoantibody activity decreases autoantibody-positive B lymphocytes and type 1 diabetes of female NOD mice
- Spatial variations in gut permeability are linked to type 1 diabetes development in non-obese diabetic mice
- Cytosolic phosphoenolpyruvate carboxykinase is expressed in α‐cells from human and murine pancreas
- Avenanthramides of oats: medicinal importance and future perspectives.
- Epidemiology of enteroviruses and their association with type 1 diabetes in Finland
- Oral tolerance therapy in type 1 diabetes mellitus
- Hypoglycemic and hypolipidemic effects of triterpenoid-enriched Jamun (Eugenia jambolana Lam.) fruit extract in streptozotocin-induced type 1 diabetic mice
- The role of metabolic flexibility in the regulation of the DNA damage response by nitric oxide
- Loss of interleukin‐10 exacerbates early Type‐1 diabetes‐induced bone loss
- Type 1 diabetes: Through the lens of human genome and metagenome interplay
- Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis and β-cell mass decline in mouse models of type 1 diabetes
- Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes
- Adoptive transfer of GRP78‐treated dendritic cells alleviates insulitis in NOD mice
- Impact of acute pancreatic injury on sphingolipid metabolism in the salivary glands
- Interleukin-27 is essential for type 1 diabetes development and sjögren syndrome-like inflammation
- Roselle (Hibiscus sabdiriffa) polyphenol-rich extract prevents testicular damage of diabetic rats
- Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk …
- The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases
- Proteomic landscape of patient-derived CD4+ T cells in recent-onset type 1 diabetes
- Carbenoxolone Could Deteriorate Streptozotocin-induced diabetes through Induction of Heat Shock Protein 70 and IFN-γ in C57BL/6 Mice
- Treatment of type 1 diabetes by regulatory T‐cell infusion via regulating the expression of inflammatory cytokines
- Usefulness of postmortem biochemistry in identification of ketosis: Diagnosis of ketoacidosis at the onset of autoimmune type 1 diabetes in an autopsy case with cold …
- New onset of diabetes in a child infected with COVID-19: a case report
- Perfluoroalkyl substances stimulate insulin secretion by islet β cells via G protein-coupled receptor 40
- Data on investigation of hypoglycemic, anti-cholesteremic, in vivo antioxidant and pancreatic beta cell protective effect of Putranjiva roxburghii Wall bark in …
- Thymic B cell-mediated attack of thymic stroma precedes type 1 diabetes development
- Pharmacological targeting of the unfolded protein response for disease intervention
- Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase
- Cells produced during in vitro β-cell differentiation characterized
- Lipid mediators and biomarkers associated with type 1 diabetes development
- Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice
- Research Article Impact of Acute pancreatic Injury on Sphingolipid Metabolism in the Salivary Glands
- Suppression of diabetes by accumulation of non–islet-specific CD8+ effector T cells in pancreatic islets
- Association of Wolfram syndrome with Fallot tetralogy in a girl
- Cutting edge: Origins, recruitment, and regulation of CD11c+ cells in inflamed islets of autoimmune diabetes mice
- Identification and Characterization of Prophages in Bacteroides Spp. Isolates from Children with Type 1 diabetes
- GPU-accelerated discovery of pathogen-derived molecular mimics of a T-cell insulin epitope
- Evaluation of pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [18F]FP-DTBZ in Healthy Subjects and Patients with Type 1 diabetes
- Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic …
- Grape seed proanthocyanidins protects against cadmium induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation and apoptosis via Nrf-2 …
- A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance
- A multi-epitope DNA vaccine enables a broad engagement of diabetogenic T cells for tolerance in Type 1 diabetes
- Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes
- Superoxide production by NADPH oxidase intensifies macrophage antiviral responses during diabetogenic coxsackievirus infection
- Aryl Hydrocarbon Receptor Activation and the Prevention of Type 1 diabetes
- Diabetogenic agent alloxan is a proteasome inhibitor
- Functional modulation of gut microbiota in diabetic rats following dietary intervention with pistachio nuts (Pistacia vera L.)
- Loss of β-cell mass—an acute event before T1DM presentation?
- Hypoglycemic effects of a Fructus Mori polysaccharide in vitro and in vivo
- Cutting edge: nonobese diabetic mice deficient in chromogranin A are protected from autoimmune diabetes
- Persistence of Coxsackievirus B4 in pancreatic ductal-like cells results in cellular and viral changes
- Study of 2009 H1N1 pandemic influenza virus as a possible causative agent of diabetes
- Autoimmune diabetes mellitus and the leaky gut
- γ-Aminobutyric acid-rich yogurt fermented by Streptococcus salivarius subsp. thermophiles fmb5 apprars to have anti-diabetic effect on streptozotocin-induced diabetic …
- BET proteins are required for transcriptional activation of the senescent islet cell secretome in type 1 diabetes
- Changes in sperm quality and testicular structure in a rat model of type 1 diabetes
- Metabolic pathways and abnormalities
- Protective effects of a polyphenol-rich extract from Syzygium cumini (L.) skeels leaf on oxidative stress-induced diabetic rats
- Children diagnosed with both type 1 diabetes and celiac disease-an Immunological challenge
- Endocrine pancreas development and regeneration: noncanonical ideas from neural stem cell biology
- Rotavirus and type 1 diabetes—is there a connection? A synthesis of the evidence
- Dietary therapy may be sufficient for type 1 diabetes treatment
- Genetics of fulminant type 1 diabetes
- Novel mutant P277 peptide VP to ameliorate atherogenic side-effects and to preserve anti-diabetic effects in NOD mice
- Nadph Oxidase-Derived Superoxide Production During Coxsackie B Virus Infection Fuels Macrophage Activation to Accelerate Type 1 diabetes
- Effects of Root Extract of Ruellia tuberosa L. on Kidneys of Diabetic Rats.
- (−)-Epicatechin-3-O-β-D-allopyranoside from Davallia formosana prevents diabetes and dyslipidemia in streptozotocin-induced diabetic mice
- Phytoremedial effect of fruit extract of Moringa oleifera on alloxan induced diabetic model in Swiss albino mice: Phytoremedial effect of fruit extract of Moringa oleifera …
- MAIT cells in type 1 diabetes mouse models
- Urinary C peptide creatinine ratio in pregnant women with normal glucose tolerance and type 1 diabetes: evidence for insulin secretion
- The emerging role of epigenetics in human autoimmune disorders
- Mouse models of virus-induced type 1 diabetes
- The expression of Tim-1 and Tim-4 molecules in regulatory T cells in type 1 diabetes
- Current and emerging agents for the treatment of hypoglycemia in patients with congenital hyperinsulinism
- P2X7R-Panx1 complex impairs bone mechanosignaling under high glucose levels associated with type-1 diabetes
- Type I IFN–Driven Immune Cell Dysregulation in Rat Autoimmune diabetes
- Type 1 diabetes mellitus with diabetic ketoacidosis after immune checkpoint inhibitor therapy
- Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 diabetes progression
- Anti-diabetic activity of Egyptian celery apigenin
- Understanding type 1 diabetes through proteomics
- Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis
- Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting
- Interleukin-13: A promising therapeutic target for autoimmune disease
- Anti-zinc transporter protein 8 antibody testing is not informative in routine prediabetes screening in young patients with autoimmune thyroiditis and celiac disease
- Genetic determinants of serum 25-hydroxyvitamin D concentration during pregnancy and type 1 diabetes in the child
- The Effect of MyD88 Expression in Dendritic Cells on Immune Function
- An altered CD8+ T cell epitope of insulin prevents type 1 diabetes in humanized NOD mice
- Timing of immunotherapy in type 1 diabetes: the earlier, the better?
- Antidiabetic activity of extracts of Pithecellobium dulce Benth leaves in alloxan induced diabetic rats
- Human fetal β islets express coagulation factor XIII-A and proteases suggesting amphicrine regulation to facilitate islet fusion
- Antidiabetic activity test of Ethanolic Seri Leave’s (Muntingia calabura L.) extract in male rats induced by Alloxan
- The antidiabetic activity of curry leaves “Murraya Koenigii” on the glucose levels, kidneys, and islets of Langerhans of rats with Streptozotocin induced diabetes
- Channeling β-cell Maturity: KATP Surface Localization Imparts Glucose Sensing
- Benzothiazole: As an antidiabetic agent
- Regulation of B cell homeostasis by Ptpn22 contributes to type 1 diabetes in NOD mice
- … Leads to Enrichment of Treg Cells Which Consequently Regulates Effector T Cell Responses in Peri-pancreatic Lymph Nodes and Pancreas of Humanized Model …
- Glycyrrhiza glabra alcoholic root extract ameliorates hyperglycemia, hyperlipidemia, and glycation‐induced free iron‐mediated oxidative reactions
- Insights on β-cell regeneration from the zebrafish shoal: from generation of cells to functional integration
- Comparative study of hypoglycemic activity of Morus alba with oral glibenclamide in streptozotocin induced diabetic rats
- Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling
- Molecular Markers and Drug Treatment for Persistent Enterovirus Infection in pancreatic Cell Lines
- Nanoparticles containing an insulin–ChgA hybrid peptide protect from transfer of autoimmune diabetes by shifting the balance between effector T cells and regulatory …
- 11-Keto-β-Boswellic Acid Inhibits Lymphocyte (CD3) Infiltration Into pancreatic Islets of Young None Obese Diabetic (NOD) Mice
- Understanding autoimmune disease: an update review
- Glutamate decarboxylase 67 contributes to compensatory insulin secretion in aged pancreatic islets
- A case of young diabetes and parasuicide
- Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity
- Immune transcriptome of cells infected with enterovirus strains obtained from cases of type 1 diabetes
- Does infant feeding modulate the manifestation of celiac disease and type 1 diabetes?
- Photobiostimulation reverses allodynia and peripheral nerve damage in streptozotocin-induced type 1 diabetes
- Endocrine effects of immunotherapy for cancer
- Co-occurrence of type 1 diabetes and celiac disease autoimmunity
- “I Live in Constant Fear of Highs,” the Daily Impact of Type 1 diabetes
- Investigation of the utility of the 1.1 B4 cell as a model human beta cell line for study of persistent enteroviral infection
- Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice
- Cytotoxic T-lymphocyte-associated protein 4+ 49A/G polymorphisms contribute to the risk of type 1 diabetes in children: An updated systematic review and …
- RESEARCH HIGHLIGHTSSelections from the
- Antidiabetic and antihyperlipidemic effects of the flower extract of Eriobotrya japonica in streptozotocin-induced diabetic mice and the potential bioactive constituents …
- The glucoregulatory response to high-intensity aerobic exercise following training in rats with insulin-treated type 1 diabetes mellitus
- Effects of Allium tuncelianum on hyperglycemia and oxidative stress in the kidney and liver tissues in rats with diabetes mellitus induced by streptozotocin
- Curcumin attenuates oxidative stress induced NFκB mediated inflammation and endoplasmic reticulum dependent apoptosis of splenocytes in diabetes
- … butyricum CGMCC0313. 1 protects against autoimmune diabetes by modulating intestinal immune homeostasis and inducing pancreatic regulatory T cells
- diabetes in Wolfram Syndrome: Update of Clinical and Genetic Aspects
- Morphometric Study of Changes in GAD 65 Expressing Beta Cell Mass In The Islets Of Langerhans In Pregnant Mice
- Rpl13a small nucleolar RNAs regulate systemic glucose metabolism
- Antidiabetic potency of jeruju (Acanthus ilicifolius L.) ethanol extract and taurine on histopathological response of mice kidney (Mus musculus L.) induced by alloxan
- Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior
- Investigation of type 1 diabetes in NOD mice knockout for the osteopontin gene
- Fluoxetine can inhibit coxsackievirus-B4 E2 in vitro and in vivo
- Hyperglycemia in a type 1 diabetes Mellitus model causes a shift in mitochondria coupled-glucose phosphorylation and redox metabolism in rat brain
- Hyperinsulinaemic hypoglycaemia—an overview of a complex clinical condition
- Evaluation of Protective Effects of Hydroalcoholic Extract of Cassia fistula Linn. Pod on Pancreas in Streptozotocin‑induced Diabetic Rats
- Loss of sympathetic innervation to islets of Langerhans in canine diabetes and pancreatitis is not associated with insulitis
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- diabetes MELLITUS A SHORT REVIEW
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- … and pharmacodynamics study of temelimab, an antipathogenic human endogenous retrovirus type W envelope monoclonal antibody, in patients with type 1 diabetes
- Assessment of anti-diabetic activity of Vinca Rosea extract on induced diabetic mice
- Roles of keratin filaments on β-cell mitochondrial behavior and functionality
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- On the emergent dynamics and synchronization of β-cells networks in response to space-time varying glucose stimuli
- Methylcellulose and polyacrylate binary hydrogels used as rectal suppository to prevent type I diabetes
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- Refractory Hypoglycemia Due to Massive Unintentional Insulin Overdose
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- … Article No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 diabetes: A 9-Year …
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- Possible interaction of sympathetic nerves with macrophages via fractalkine-CX3CR1 ligation in pancreatic islets
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- GLP-1/Exendin-4 induces β-cell proliferation via the epidermal growth factor receptor
- Future glycemic control of children diagnosed with type 1 diabetes mellitus at toddler and preschool/school age
- Al Humayed
- Infectious triggers
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- Mechanisms of Igf2 inhibition in thymic epithelial cells infected by coxsackievirus CV-B4
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- Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis
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- Coxsackievirus-B4 infection can induce the expression of human endogenous retrovirus W in primary cells
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- Genetic and Immunological Features of Insulin-Dependent diabetes Mellitus as a Clinical Manifestation of Type 1 Autoimmune Polyglandular Syndrome
- Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut …
- Congenital hyperinsulinism due to compound heterozygous mutations in ABCC8 responsive to diazoxide therapy
- Antibiotic-associated manipulation of the gut microbiota and phenotypic restoration in NOD mice
- Immunogenetic Prediction of VDR Gene SNPs: Lack of Association with Susceptibility to Type 1 diabetes in Jordanian Patients
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- Effect of flavonoid rich fraction of Tephrosia purpurea (Linn.) Pers. on complications associated with streptozotocin-induced type I diabetes mellitus
- New developments implicating IL-21 in autoimmune disease
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- The Evaluation of Serum IFN-γ and TGF-β in Some Patients with Type1 diabetes mellitus in Al-diwanyah Province
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- Regulatory B cells in an experimental model of type 1 diabetes
- Exopolysaccharide from Leuconostoc pseudomesenteroides XG5 delay the onset of autoimmune diabetes by modulating gut microbiota and its metabolites …
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- Assessment of metals induced histopathological and gene expression changes in different organs of non-diabetic and diabetic rats
- Taming autoimmunity: Translating antigen-specific approaches to induce immune tolerance
- Transdifferentiation of both intra-and extra-islet cells into beta cells in nicotinamide treated neonatal diabetic rats: An in situ hybridization and double …
- Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas
- Assessment of growth among children with type 1 diabetes mellitus: A cross-sectional study of factors contributing to stunting
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- Mitochondrial uncoupling proteins regulate angiotensin‐converting enzyme expression: crosstalk between cellular and endocrine metabolic regulators suggested by …
- Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes
- A century of progress
- LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function
- Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune …
- Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity
- Screening for coeliac disease in adult patients with type 1 diabetes mellitus: myths, facts and controversy
- Emerging role of air pollution in autoimmune diseases
- Dimethyl fumarate ameliorates diabetes-associated vascular complications through ROS-TXNIP-NLRP3 inflammasome pathway
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- Insulin/adenosine axis linked signalling
- Aqueous extract of Digitaria exilis grains ameliorate diabetes in streptozotocin-induced diabetic male Wistar rats
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- Ameliorative role of ferulic acid against diabetes associated oxidative stress induced spleen damage
- In vivo evidences of Curcuma longa on oxidative stress in STZ-induced diabetes on sperm parameters in male wistar rats
- Association of HLA class II alleles and haplotypes with type 1 diabetes in Tunisian Arabs
- miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity
- Aegle marmelos Leaf Extract is an Effective Herbal Remedy in Reducing Hyperglycemic Condition: A Pre-clinical Study
- Associations of CTLA4 +49 A/G Dimorphism and HLA-DRB1*/DQB1* Alleles With Type 1 diabetes from South India
- Low CD25 on autoreactive Tregs impairs tolerance via low dose IL-2 and antigen delivery
- AND TYPE 1 diabetes
- Ghrelin mitigates β‐cell mass loss during insulitis in an animal model of autoimmune diabetes mellitus, the BioBreeding/Worcester rat
- Insulin-loaded hydroxypropyl methyl cellulose-co-polyacrylamide-co-methacrylic acid hydrogels used as rectal suppositories to regulate the blood glucose of diabetic …
- Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model
- Enteric parasitic infection disturbs bacterial structure in Mexican children with autoantibodies for type 1 diabetes and/or celiac disease.
- Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway
- Expression of adenosine receptors in rodent pancreas
- Highlight: IL-2 receptor signaling
- Research Article Protective Effects of a Polyphenol-Rich Extract from Syzygium cumini (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats
- Possible link of genetic variants to autoimmunity in GAD-antibody-associated neurological disorders
- Radioprotective Effects of Allium jesdianum Extract on Reduction of Pancrease Damages Following γ-Radiation through Down-regulation of Apoptotic Genes …
- Intestinal permeability and autoimmune diseases
- Androgen derivatives affect immunopresence but not activity of antioxidant enzymes in pancreatic islets during diabetogen-induced apoptosis
- Asparaginyl ligase-catalyzed one-step cell surface modification of red blood cells
- Closed-Loop Blood Glucose Control for Type I diabetes Patients Using PID Controller
- Evidence of immunosuppressive and Th2 immune polarizing effects of antidiabetic momordica charantia fruit juice
- Hypoglycemic and antioxidant effects of Hibiscus rosa-sinensis L. leaves extract on liver and kidney damage in streptozotocin induced diabetic rats
- Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review
- Case 17: Wolfram Syndrome WFS1
- Inhibition of coxsackievirus B4 by Lactobacillus plantarum
- The antidiabetic activity of Nigella sativa and propolis on streptozotocin-induced diabetes and diabetic nephropathy in male rats
- Study of hypoglycemic effect of corosolic acid & its comparative evaluation with standard drug glibenclamide in alloxan induced diabetes in female albino mice
- Influence of aerobic exercise training on serum markers of oxidative stress in diabetic rats
- Shared and unique immune alterations in pre-clinical autoimmunity
- Antidiabetic and antioxidant activities of extract of entandrophragma cylindricum (sprague) leaves in male wistar rats
- Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L
- Roles of microRNAs in chronic pediatric diseases and their use as potential biomarkers: A review
- De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes
- Development of a neonatal mouse model for coxsackievirus B1 antiviral evaluation
- Association Between Enterovirus Infections and Type 1 diabetes in Different Countries
- Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity
- A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells
- Null mutations of NEUROG3 are associated with delayed-onset diabetes mellitus
- ASIA syndrome and endocrine autoimmune disorders
- Antioxidant and anti-inflammatory effects of curcumin nanoparticles on drug-induced acute myocardial infarction in diabetic rats
- Low-level fluoride exposure reduces glycemia in NOD mice
- Pancreas development and the Polycomb group protein complexes
- Effects of garlic extract on TNF-α expression and oxidative stress status in the kidneys of rats with STZ+ nicotinamide-induced diabetes
- Breakdown in peripheral immune tolerance in experimental diabetes Mellitus
- EVALUATION OF ANTIDIABETIC ACTIVITY OF WHOLE PLANT OF 70% ETHANOLIC EXTRACTS OF INDIGOFERABARBERI GAMBLES
- A Protective Role for NKG2D–H60a Interaction via Homotypic T Cell Contact in Nonobese Diabetic Autoimmune diabetes Pathogenesis
- The murine natural cytotoxic receptor NKp46/NCR1 controls TRAIL protein expression in NK cells and ILC1s
- Anti PD-1 monoclonal antibody induced autoimmune diabetes mellitus: a case report and brief review
- Chaos and coexisting attractors in glucose-insulin regulatory system with incommensurate fractional-order derivatives
- Engineering commensal bacteria to rewire host–microbiome interactions
- Protein A functionalized polyelectrolyte microcapsules as a universal platform for enhanced targeting of cell surface receptors
- Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation
- Probiotic treatment reduces appetite and glucose level in the zebrafish model
- Activation of the aryl hydrocarbon receptor by 10-Cl-BBQ prevents insulitis and effector T cell development independently of Foxp3+ regulatory T cells in nonobese …
- Polyphenolic composition, enzyme inhibitory effects ex-vivo and in-vivo studies on two Brassicaceae of north-central Italy
- Immunohistochemical and biochemical study of the effect of Rheum ribes on the pancreas of diabetic rats
- Antihyperglycemic, antihyperlipidemic and hepatoprotective effects of Ficus ottoniifolia (Miq.) Miq. supplementation in alloxan-induced diabetic rats
- MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites
- Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis
- Preproinsulin autoantigen processing by ER aminopeptidase 1 is upregulated during ER stress via IRE1α-mediated miR-17 degradation
- β‐Catenin stabilization in NOD dendritic cells increases IL‐12 production and subsequent induction of IFN‐γ‐producing T cells
- Infections: a double-edge sword in autoimmunity
- Adoptive transfer of mRNA-transfected T cells redirected against diabetogenic CD8 T cells can prevent diabetes
- Biological Activities of Red Pepper (Capsicum annuum) and Its Pungent Principle Capsaicin: A Review
- Comprehensive analysis of liver and blood miRNA in precancerous conditions
- Wilson Disease With Novel Compound Heterozygote Mutations in the ATP7B Gene Presenting With Severe diabetes
- Stimulator of interferon genes agonists attenuate type I diabetes progression in NOD mice
- Role of NFAT5 in the immune system and pathogenesis of autoimmune diseases
- Antidiabetic effects of fermented milk contained with Gardenia jasminoides water extracts on streptozotocin‐induced mice
- Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune …
- Excess of glucocorticoids during late gestation impairs the recovery of offspring’s β‐cell function after a postnatal injury
- Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats
- Origins of brain insulin and its function
- Effect of ginger on hyperglycemia induced by streptozotocin in pregnant rats and postnatal neurodevelopment of their offspring
- Identification of four novel mutations of the WFS1 gene in Iranian Wolfram syndrome pedigrees
- Changes in the composition and function of the gut microbiome accompany type 1 diabetes in pregnancy
- Continuous glucose monitoring systems for the diagnosis of cystic fibrosis‐related diabetes
- Pharmacological activity and flavonoids constituents of Artemisia judaica L aerial parts
- pancreatic ductal cell antigens are important in the development of invasive insulitis in non-obese diabetic mice
- Anti-hyperglycemic activity of polyherbal formulation (Herbinsulplus) in experimental diabetes and its effects on key metabolic enzymes of carbohydrate metabolism
- 25-Hydroxyvitamin D and peripheral immune mediators: results from two nationwide Danish pediatric cohorts
- Unique features in the presentation of insulin epitopes in autoimmune diabetes: an update
- Heparanase: historical aspects and future perspectives
- Insights on the effects of resveratrol and some of its derivatives in cancer and autoimmunity: a molecule with a dual activity
- Ameliorative effects of aloe vera gel extract on circulatory and tissue lipid profile status in streptozotocin-induced diabetic rats
- Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3β, P-GSK3β pathway
- Synthesis and characterization of [125I] TZ6544, a promising radioligand for investigating sphingosine-1-phosphate receptor 2
- Antidiabetic and anti-hyperlipidemic effects of ethanolic extract of Dryopteris dilatata leaves
- Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-specific T cell responses to multiple antigens and protect from autoimmune …
- pancreatic inflammation redirects acinar to β cell reprogramming
- Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
- Effect of Boswellia serrata supplementation in addition to insulin on glycemic control in a diabetic dog
- Protective effect of quercetin on alteration of antioxidant genes expression and histological changes in the dental pulp of the streptozotocin-diabetic rats
- Antidiabetic Activity of Indian Medicinal Plants
- Anti‐inflammatory effects of melatonin in multiple sclerosis
- Role of exercise on S-Klotho protein regulation: a systematic review
- Implication of Vitamin D Deficiency on Autoimmune Disorders
- An in vitro evaluation of anti-aging effect of guluronic acid (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs
- Oral supplementation with p‐coumaric acid protects mice against diabetes‐associated spontaneous destruction of periodontal tissue
- The multifaceted functional role of DNA methylation in immune-mediated rheumatic diseases
- Effects of Talinum triangulare leaf flavonoid extract on streptozotocin‐induced hyperglycemia and associated complications in rats
- MHC class I expression in intestinal cells is reduced by rotavirus infection and increased in bystander cells lacking rotavirus antigen
- Nanoparticles versus dendritic cells as vehicles to deliver mRNA encoding multiple epitopes for immunotherapy
- Effect of glabridin on collagen deposition in liver and amelioration of hepatocyte destruction in diabetes rats
- Blood leukocytes recapitulate diabetogenic peptide–MHC-II complexes displayed in the pancreatic islets
- Heparan Sulfate of ß Cells Regulates Insulin Secretion and Contributes to Normal Glucose Homeostasis
- Prevalence of exposure of heavy metals and their impact on health consequences
- Antidiabetic activity of phytosaponin in STZ-induced type I diabetes in rats
- De novo germline mutation in the Dual Specificity Phosphatase 10 gene accelerates autoimmune diabetes in Non-Obese Diabetic (NOD) mice
- Decreased 68Ga-NOTA-exendin-4 renal uptake in patients pretreated with Gelofusine infusion: a randomized controlled study
- Expression of Pichia pastoris-derived secreted insulin precursor
- Urinary Tract Involvement in Wolfram Syndrome: A Narrative Review
- Protective role of Excoecaria agallocha L. against streptozotocin-induced diabetes and related complications
- Regulated endocrine-specific protein-18, an emerging endocrine protein in physiology: A literature review
- Flexible Bayesian joint models for longitudinal biomarkers and time-to-event outcomes with applications to type 1 diabetes research
- Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites
- APPRAISAL OF PHYTOCONSTITUENTS AND ANTI-DIABETIC PROPERTIES OF THE STEM BARK EXTRACT OF ANISOPUS MANNIIIN ALLOXAN INDUCED …
- Direct cell reprogramming for tissue engineering and regenerative medicine
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- Ectopic expression of Pax4 in pancreatic δ cells results in β-like cell neogenesis
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- Studying the heterogeneous pathogenesis of canine diabetes: Observational characterization of an island population
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- PLAGL1: an important player in diverse pathological processes
- Research Article Evidence of Immunosuppressive and Th2 Immune Polarizing Effects of Antidiabetic Momordica charantia Fruit Juice
- T Cells from NOD-PerIg Mice Target Both pancreatic and Neuronal Tissue
- Endocrinopathy and aging in ferrets
- Molecular Imaging of Autoimmune Diseases
- The improvement effects of Gordonia bronchialis on male fertility of rats with diabetes mellitus induced by streptozotocin
- 110-OR: Generation of a Novel Mouse Model to Study ß-Cell Proliferation
- EVALUATION OF ANTIDIABETIC ACTION OF ARAUCARIA COLUMNARIS LEAF EXTRACTS
- High glucose-induced ubiquitylation of G6PD leads to the injury of podocyte
- PTY 2 As DPP-IV Inhibitor Prevents Intestinal Cell’s Apoptosis
- Role of gut microbiota in autoimmune diseases: a review
- Effect of alpha-lipoic acid on antioxidant gene expression and kidney injury in alloxan-induced diabetic rats.
- Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner
- Mycobacteria, Immunoregulation, and Autoimmunity
- The clearance of dead cells by efferocytosis
- A new role for NKG2D signaling in CD8+ T cells and autoimmune diabetes
- The burden of congenital hyperinsulinism in the United Kingdom: a cost of illness study
- Anti-diabetic activity of hydro-alcoholic root extract of echinops echinatus and its beneficial effects on nephropathy in experimental rats
- Silymarin ameliorates liver damage by modulating oxidative stress and apoptosis in liver of streptozotocininduced diabetic rats
- Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27 histone modification
- Two-photon imaging of pancreatic beta cells in real time in vivo
- Impaired glucose tolerance after streptozotocin microinjection into the mediodorsal prefrontal cortex of the rat
- Probiotics: Role in the Prevention of Chronic Viral Diseases
- Forkhead transcription factors in health and disease
- Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action
- Nigella sativa L. seed and seed oil: potential sources of high-value components for development of functional foods and nutraceuticals/pharmaceuticals
- CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins
- Antioxidant Enzymes and Lipid Peroxidation in Alloxan-Induced Diabetic Rabbits
- Assessing the anti-hyperglycemic and anti-hyperlipidemic effects of an aqueous extract of lannea edulis in alloxan-induced diabetic rats
- Opuntia stricta cladode Extract reduces blood glucose levels in Alloxan-induced diabetic mice.
- Insulin influences LPS-Induced TNF-α and IL-6 release through distinct pathways in mouse macrophages from different compartments
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- Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: From pathogenic factors to therapeutic targets
- The importance of educational activities promoting health in obstetrics and gynaecology—selected issues taking into account nutritional aspects
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- Synthesis and antidiabetic activity of selenium nanoparticles in the presence of polysaccharides from Catathelasma ventricosum
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- Role of endocannabinoid CB1 receptors in Streptozotocin-induced uninephrectomised Wistar rats in diabetic nephropathy
- Effects of Low-Level Laser Therapy on Tooth Socket Repair in Diabetic Male Rats: An Animal Study
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- Preproinsulin designer antigens excluded from endoplasmic reticulum suppressed diabetes development in NOD mice by DNA vaccination
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- Hypoglycemic, Antihyperlipidemic and Antioxidant Effects of Manniophyton fulvum Aqueous Root Extract on Streptozotocin-induced Hyperglycemic Wistar Rats
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- Basics of inducible lymphoid organs
- Effect of Hydroalcoholic Extract of Cynodon Dactylon on Clinical and Histopathological Aspects and Leukocyte Infiltrations of Pancreas in Experimental Autoimmune …
- ROS-associated immune response and metabolism: a mechanistic approach with implication of various diseases
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- The treatment of hyperinsulinemic hypoglycaemia in adults: an update
- Coxsackievirus B4 transplacental infection severely disturbs central tolerogenic mechanisms in the fetal thymus
- Evaluation of in vitro antioxidant activity of okra mucilage and its antidiabetic and antihyperlipidemic effect in alloxan‐induced diabetic mice
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- Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development
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- The individual and joint effects of maternal 25 (OH) D deficiency and gestational diabetes on infant birth size
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- An overview of tolerogenic immunotherapies based on plant-made antigens
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- Collective genetic interaction effects and the role of antigen-presenting cells in autoimmune diseases
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- Effect of Zanthoxylum alkylamides on glucose metabolism in streptozotocin-induced diabetic Sprague–Dawley rats
- Toll-like receptor-mediated immune responses in intestinal macrophages; implications for mucosal immunity and autoimmune diseases
- MicroRNA expression in antiphospholipid syndrome: a systematic review and microRNA target genes analysis
- Dynamic proteomic analysis of pancreatic mesenchyme reveals novel factors that enhance human embryonic stem cell to pancreatic cell differentiation
- Functional domains of autoimmune regulator (AIRE) modulate INS-VNTR transcription in human thymic epithelial cells
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- Serum metabolic fingerprinting identified putatively annotated sphinganine isomer as a biomarker of Wolfram syndrome
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- PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions
- Genetic characteristics and long-term follow-up of 11 patients with congenital hyperinsulinism followed in a single center
- Non-Lyn src family kinases activate SIRPα–SHP-1 to inhibit PI3K–Akt2 and dampen proinflammatory macrophage polarization
- T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8
- Generalizing RNA velocity to transient cell states through dynamical modeling
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- A review on the effectiveness of oral insulin in type I and type II diabetes mellitus
- Role of extracellular vesicles in cell death and inflammation
- Adaptation of striated muscles to Wolframin deficiency in mice: alterations in cellular bioenergetics
- Botryosphaeran reduces obesity, hepatic steatosis, dyslipidaemia, insulin resistance and glucose intolerance in diet-induced obese rats
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- INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells
- 4.2 Capítulo II-Protective effects of a polyphenol-rich extract from Syzygium cumini (L.) Skeels leaf on oxidative stress-induced diabetic rats
- Anticipating regime shifts in gene expression: The case of an autoactivating positive feedback loop
- Targeting mitochondria with folic acid and vitamin B12 ameliorates nicotine mediated islet cell dysfunction
- Red Wine and Yacon as a Source of Bioactive Compounds with Antidiabetic and Antioxidant Potential
- The chemistry and pharmacology of genistein
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- Case reports of pre-clinical replication studies in metabolism and diabetes
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- MicroRNA expression profiles of human iPSCs differentiation into insulin-producing cells
- Modulation of IGF2 expression in the murine thymus and thymic epithelial cells following coxsackievirus-B4 infection
- Identification and characterization of anti-diabetic principle in Senna alata (Linn.) flower using alloxan-induced diabetic male Wistar rats
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- Immunoengineering approaches for cytokine therapy
- In silico and ex vivo approaches indicate immune pressure on capsid and non-capsid regions of coxsackie B viruses in the human system
- Increased expression of pyloric ERβ is associated with diabetic gastroparesis in streptozotocin-induced male diabetic rats
- An evaluation of the antioxidant and antidiabetic potential of Cynometra cauliflora (nam-nam, Fabaceae)
- Nanoceria, the versatile nanoparticles: Promising biomedical applications
- Effect of levosimendan, an inodilator, on streptozotocin-induced diabetic nephropathy in rats
- Neutrophils in animal models of autoimmune disease
- Preventive effect of phloroglucinol against adverse protein alterations in streptozotocin induced diabetic rats
- PROFILES IN FORENSIC TOXICOLOGY
- Novel Spatiotemporal Analysis for Exploring a-Cell Differentiation
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- First report of insulin receptor in Thysanoptera and its expression variation with development of western flower thrips, Frankliniella occidentalis
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- Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers
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- Streptomyces strains producing mitochondriotoxic antimycin A found in cereal grains
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- Effect of melatonin on hypertension and diabetes induced experimentally in adult male albino rats
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- Physical exercise as a modulator of the anti-ageing Klotho protein: health-related cardiometabolic implications. The FIT-AGEING study
- Involvement of spinal angiotensin II system in streptozotocin-induced diabetic neuropathic pain in mice
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- Redox Enzymes of the Thioredoxin Family as Potential and Novel Markers in Pemphigus
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- Sodium transporters in human health and disease
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- Genetic analysis of endoplasmic reticulum homeostasis during stress and infection of Caenorhabditis elegans
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- Cellular senescence in vivo: From cells to tissues to pathologies
- Roles of Phosphatidylinositol 4-Phosphate in Secretory Granule Biogenesis
- Rossmann MG, Arnold E, Erickson JW, et al. Structure of a human common cold virus and functional relationship to other picornaviruses. Nature 1985; 317: 145–153 …
- Sensitivity and Specificity of Diagnostic Biomarkers in Thyroid Diseases: From circulating chemistry to molecular cytogenetics.
- Effects of carbohydrate supplementation on resistance exercise performance, blood glucose, endocrine and metabolite responses, immediately before exercise and …
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- Development of tools for the analysis of cell-free DNA in human blood: Application in the noninvasive prenatal testing field
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- Oral dysbiosis and autoimmunity: from local periodontal responses to an imbalanced systemic immunity. A review
- Collection of initial and current control tests for 4th course students of medical and pediatric faculties content modules: gastroenterology, endocrinology, pulmonology …
- Phosphometabolite Enrichment With Metal Oxide Microtips and Purification of Albumin From Canine Plasma
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- Management of asymptomatic patients with positive coronary artery calcium scans
- The cytoprotective activity of Nrf2 is regulated by phytochemicals (sulforaphane, curcumin, and silymarin)
- Gastrointestinal disease 358
- Brain inflammation and neuronal activity in diabetes and metabolic syndrome
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- Identification of a novel WFS1 homozygous nonsense mutation in Jordanian children with Wolfram syndrome
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- Evaluating the contribution of immune gene variants to schizophrenia
- The role of invariant natural killer T Cells in autoimmune diseases
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- The role of heat-shock proteins and chaperonins in the pathogenesis and progression of cancer
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- Investigating the effects of host factors (proteins and non-proteins) on mycobacteria
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- Investigating the role of Junctional Adhesion Molecule-C (JAM-C) in endothelial cell biology in vitro and in vivo using human and mouse models
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- Control of mast cell regulated exocytosis by Munc18 proteins
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- Partial clinical remission of type 1 diabetes: the need for an integrated functional definition based on insulin-dose adjusted A1c and insulin sensitivity score
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- Toll-Like Receptor 3 Is Critical to the pancreatic Islet Milieu That Is Required for Coxsackievirus B4–Induced Type 1 diabetes in Female Nonobese Diabetic …
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- Association of Vitamin D deficiency and vitamin D receptor gene polymorphisms with type 1 diabetes risk: A South Indian familial study
- Glycemic variability patterns strongly correlate with partial remission status in children with newly diagnosed type 1 diabetes
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- NLRP6 deficiency expands a novel CD103+ B cell population that confers immune tolerance in NOD mice
- Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes
- Case report: Better late than never, but sooner is better: switch from CSII to sulfonylureas in two patients with neonatal diabetes due to KCNJ11 variants
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- High serum Vitamin D concentrations, induced via diet, trigger immune and intestinal microbiota alterations leading to type 1 diabetes protection in NOD mice
- Viral infection‐related gene upregulation in monocytes in children with signs of β‐cell autoimmunity
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