Gambogic Acid (Garcinia hanburyi)
- Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents
- Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
- The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Receptor-mediated Peroral Transport Utilizing gambogic acid as a Ligand
- Crystallization of Pseudopolymorphs of Some Gamboge Pigments. Pyridine, Dimethylformamide and Dimethylsulfoxide Solvates of Morellic Acid, gambogic acid and Guttiferic Acid
- Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid
- 1213901. Synthesis and anti-tumor activity of NO-donating derivatives of gambogic acid
- 345. Gamboge. Part I. The constitutions of the acids C 11 H 10 O 4 and C 12 H 10 O 6 derived from gambogic acid
- 47 gambogic acid delivery using lipid nanoparticles modified with cell-penetrating peptide
- A novel dual sensitive polymer-gambogic acid conjugate: synthesis, characterization, and in vitro evaluation
- A novel exploration of a combination of gambogic acid with TiO2 nanofibers: The photodynamic effect for HepG2 cell proliferation
- A novel redox/pH dual-responsive and hyaluronic acid-decorated multifunctional magnetic complex micelle for targeted gambogic acid delivery for the treatment of …
- A Probe into mechanism of gambogic acid-induced apoptosis in SPC-A-1 lung adenocarcinoma cells [J]
- A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid
- A solvent-assisted active loading technology to prepare gambogic acid and all-trans retinoic acid co-encapsulated liposomes for synergistic anticancer therapy
- Absolute configuration of (−)-gambogic acid, an antitumor agent
- Abstract# 4392: Role of transferrin receptor 1 and Src in gambogic acid-induced apoptosis
- Advance on Mechanisms in Antitumor Effect of gambogic acid and Its Derivates [J]
- Aminated β-cyclodextrin-grafted Fe 3 O 4-loaded gambogic acid magnetic nanoparticles: preparation, characterization, and biological evaluation
- Aminated β-cyclodextrin-grafted Fe₃O₄-loaded gambogic acid magnetic nanoparticles: preparation, characterization, and biological evaluation
- An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors
- An open-labeled, randomized, multicentered, phase IIa study for advanced cancer treatment by gambogic acid injection (THS).
- An oxidative analogue of gambogic acid-induced apoptosis of human hepatocellular carcinoma cell line HepG2 is involved in its anticancer activity in vitro
- Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823
- Anticancer effect and apoptosis induction of gambogic acid in human leukemia cell line K562 in vitro
- Anticancer effect of gambogic acid in gastric cancer line SGC-7901
- Anti-CD22-conjugated CdTe QDs co-loaded with doxorubicin and gambogic acid: a novel platform for lymphoma treatment
- Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal …
- Anti‑inflammatory effects of gambogic acid in murine collagen‑induced arthritis through PI3K/Akt signaling pathway
- Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells
- Antimetastatic Effects of gambogic acid are Mediated via the Actin Cytoskeleton and NF‐κ B Pathways in SK‐HEP 1 Cells
- Antiproliferative activity of gambogic acid isolated from Garcinia hanburyi in Hep3B and Huh7 cancer cells
- Antitumor activity of gambogic acid on NCI-H1993 xenografts via MET signaling pathway downregulation
- Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid
- Apoptosis-inducing effect of gambogic acid on K562 cells and its mechanism
- Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathway
- Application of Probe Drugs for Detecting Influences of gambogic acid on Cytochrome P450 Isoforms
- Autophagy inhibition promotes gambogic acid-induced suppression of growth and apoptosis in glioblastoma cells
- Bromodomain‑containing protein 4 is critical for the antiproliferative and pro‑apoptotic effects of gambogic acid in anaplastic thyroid cancer
- Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation
- Caspase-8 preferentially senses the apoptosis-inducing action of NG-18, a gambogic acid derivative, in human leukemia HL-60 cells
- CD44 targeted redox-triggered self-assembly with magnetic enhanced EPR effects for effective amplification of gambogic acid to treat triple-negative breast cancer
- Cell penetrating peptides functionalized gambogic acid-nanostructured lipid carrier for cancer treatment
- Cell-penetrating peptide conjugates of gambogic acid enhance the antitumor effect on human bladder cancer EJ cells through ROS-mediated apoptosis
- Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer
- Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP …
- Combined therapy with EGFR TKI and gambogic acid for overcoming resistance in EGFR‑T790M mutant lung cancer
- Comparative studies on biophysical interactions between gambogic acid and serum albumin via multispectroscopic approaches and molecular docking
- Comparison of electron capture—atmospheric pressure chemical ionization and electrospray ionization for the analysis of gambogic acid and its main circulating …
- Computational study on the conformations of gambogic acid
- Crystal structure of the pyridine salt of gambogic acid
- Cytotoxic effect of gambogic acid on SH-SY5Y neuroblastoma cells is mediated by intrinsic caspase-dependent signaling pathway
- Daunorubicin and gambogic acid coloaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo
- Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents
- Determination of Content and Entrapment Efficiency of Neo-gambogic acid Nanoparticles by HPLC
- Determination of gambogic acid in dog plasma by high‐performance liquid chromatography for a pharmacokinetic study
- Determination of gambogic acid in Gamboge by non-aqueous capillary electrophoresis
- Determination of gambogic acid in human plasma by liquid chromatography-atmospheric pressure chemical ionization–mass spectrometry
- Determination of the content of gambogic acid and gambogenic acid in gamboge by HPLC
- Determination of the Content of gambogic acid and Neo-gambogic acid in Gamboge by HPLC
- Determination of Total gambogic acid in Gamboge by ZrOCl_2 Colorimetry
- Development of a more efficient albumin-based delivery system for gambogic acid with low toxicity for lung cancer therapy
- Development of a safety and efficacy nanoemulsion delivery system encapsulated gambogic acid for acute myeloid leukemia in vitro and in vivo
- Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
- Dimeric c (RGD) peptide conjugated nanostructured lipid carriers for efficient delivery of gambogic acid to breast cancer
- Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay
- Down-regulation of chemokine receptor CXCR4 by gambogic acid suppresses metastasis of pancreatic cancer in an orthotopic mouse model
- Effect of gambogic acid on cell apoptosis and expressions of Bax, Bcl-2 and Caspase-3 in colorectal cancer cells with
- Effect of gambogic acid on proliferation and apoptosis in 786-O cells
- Effect of gambogic acid on proliferation and apoptosis of human diffuse large B-cell lymphoma cell line OCI-LY-1
- Effect of gambogic acid on proliferation and invasion in colon cancer LoVo cell line
- Effect of gambogic acid on proliferation of SKM-1 cells and its mechanism
- Effect of gambogic acid on the proliferation of human colon carcinoma cell SW480 and the expression of VEGFR2 [J]
- Effect of gambogic acid on the regulation of hERG channel in K562 cells in vitro
- Effect on proliferation and apoptosis and regulation on nucleoporin Nup88 in acute leukemic cell U937 by gambogic acid
- Effects of gambogic acid on Bladder Cancer Cells
- Effects of gambogic acid on human telomerase reverse transcriptase and Bcl-2 protein in human osteosarcoma cells
- Effects of gambogic acid on regulation of steroid receptor coactivator-3 in lung adenocarcinoma A549 cells
- Effects of gambogic acid on the activation of caspase-3 and downregulation of SIRT1 in RPMI-8226 multiple myeloma cells via the accumulation of ROS
- Effects of gambogic acid on the Production of Reactive Oxygen Species and Neutrophil Extracellular Traps
- EFFECTS OF gambogic acid ON THE PROLIFERATION AND CELL APOPTOSIS OF CELL LINE NCI-H929IN MULTIPLE MYELOMA
- Effects of gambogic acid on the regulation of nucleoporin Nup88 in HL-60 cells
- Effects of gambogic acid on the regulation of nucleoporin Nup88 in U937 cells
- Effects of gambogic acid on the regulation of steroid receptor coactivator-3 in A549 cells
- Effects of magnetic nanoparticle Fe_3O_4 on apoptosis of HepG2 cells induced by gambogic acid
- Effects of magnetic nanoparticle of Fe3O4 on apoptosis induced by gambogic acid in U937 leukemia cells.
- Effects of magnetic nanoparticles of Fe3O4 combinated with gambogic acid on apoptosis of SMMC-7721 cells
- Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic …
- Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells
- Evaluation of in vitro and in vivo antitumor effects of gambogic acid-loaded layer-by-layer self-assembled micelles
- Experimental study on effects of gambogic acid with cisplatin to human osteosarcoma cells
- Experimental study on gambogic acid-induced gastric cancer cell apoptosis and anti-tumor metastasis
- Experimental study on gambogic acid-induced gastric cancer cell apoptosis and anti-tumor metastasis.
- Exploration of acute genotoxic effects and antigenotoxic potential of gambogic acid using Allium cepa assay
- Fine-tuning vitamin E-containing telodendrimers for efficient delivery of gambogic acid in colon cancer treatment
- Folate‐decorated arginine‐based poly (ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells
- Functional inhibition of Hsp70 by Pifithrin-μ switches gambogic acid induced caspase dependent cell death to caspase independent cell death in human …
- GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms
- Gamboge. Part IV. Scission of gambogic acid by alkali
- gambogic acid
- gambogic acid activates AMP-activated protein kinase in mammalian cells
- gambogic acid Affects Ribosomal Occurrence in Glioma Cells by Downregulating the Phosphoinositide Kinase-3/Protein Kinase B/Mammalian Target of Rapamycin …
- gambogic acid ameliorates diabetes-induced proliferative retinopathy through inhibition of the HIF-1α/VEGF expression via targeting PI3K/AKT pathway
- gambogic acid ameliorates diabetes-induced proliferative retinopathy through inhibition of the HIF-1α/VEGF expression via targeting PI3K/AKT pathway
- gambogic acid and celastrol are two powerful anti-inflammatory drugs in arthritis
- gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi
- gambogic acid and inhibition of tumor growth: a close association
- gambogic acid and its analogs inhibit gap junctional intercellular communication
- gambogic acid and its role in chronic diseases
- gambogic acid as a Non‐Competitive Inhibitor of ATP‐Binding Cassette Transporter B1 Reverses the Multidrug Resistance of Human Epithelial Cancers by …
- gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90
- gambogic acid binds to human CB2 receptors and exhibits potential partial agonist activity
- gambogic acid causes fin developmental defect in zebrafish embryo partially via retinoic acid signaling
- gambogic acid combined with CdTe QDs for leukemia cancer cells inhibition and their bio-safety for rat brain
- gambogic acid counteracts mutant p53 stability by inducing autophagy
- gambogic acid covalently interacts with IKK-2 to inhibit the NF-kB signaling pathway
- gambogic acid covalently modifies IκB kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages
- gambogic acid deactivates cytosolic and mitochondrial thioredoxins by covalent binding to the functional domain
- gambogic acid disrupts toll-like receptor4 activation by blocking lipopolysaccharides binding to myeloid differentiation factor 2
- gambogic acid down-regulates MDM2 oncogene and induces p21Waf1/CIP1 expression independent of p53
- gambogic acid efficiently kills stem-like colorectal cancer cells by upregulating zfp36 expression
- gambogic acid enhances proteasome inhibitor-induced anticancer activity
- gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway
- gambogic acid exerts cardioprotective effects in a rat model of acute myocardial infarction through inhibition of inflammation, iNOS and NF‑κB/p38 pathway
- gambogic acid exhibits anti-metastatic activity on malignant melanoma mainly through inhibition of PI3K/Akt and ERK signaling pathways
- gambogic acid exhibits anti-psoriatic efficacy through inhibition of angiogenesis and inflammation
- gambogic acid grafted low molecular weight heparin micelles for targeted treatment in a hepatocellular carcinoma model with an enhanced anti-angiogenesis effect
- gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90β
- gambogic acid impairs tumor angiogenesis by targeting YAP/STAT3 signaling axis
- gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway
- gambogic acid increases the sensitivity to paclitaxel in drug‑resistant triple‑negative breast cancer via the SHH signaling pathway
- gambogic acid Induced Apoptosis through Activation of Caspase-dependent Pathway in Aortic Smooth Muscle Cells
- gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1 …
- gambogic acid induced tumor cell apoptosis by T lymphocyte activation in H22 transplanted mice
- gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways
- gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells
- gambogic acid induces apoptosis and sensitizes TRAIL-mediated apoptosis through downregulation of cFLIPL in renal carcinoma Caki cells
- gambogic acid induces apoptosis by regulating the expression of Bax and Bcl‐2 and enhancing caspase‐3 activity in human malignant melanoma A375 cells
- gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition
- gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase
- gambogic acid Induces Apoptosis in Imatinib-Resistant
- gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl …
- gambogic acid induces apoptosis of human malignant melanoma A375 cells
- gambogic acid induces apoptosis of Jurkat cell through the MAPK signal pathway
- gambogic acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling
- gambogic acid induces apoptosis of SK-MES-1 lung cancer cells
- gambogic acid induces apoptotic cell death in T98G glioma cells
- gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive …
- gambogic acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN−/−/p53−/− Prostate Cancer Cells In Vitro and Ex Vivo
- gambogic acid induces cell apoptosis through endoplasmic reticulum stress triggered inhibition of Akt signaling pathways in extranodal NK/T-cell lymphoma cells
- gambogic acid induces death inducer‐obliterator 1‐mediated apoptosis in Jurkat T cells
- gambogic acid induces death of K562 cells through autophagy and apoptosis mechanisms
- gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells
- gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells
- gambogic acid induces G0/G1 cell cycle arrest and cell migration inhibition via suppressing PDGF receptor β tyrosine phosphorylation and Rac1 activity in rat aortic …
- gambogic acid induces growth inhibition and differentiation via upregulation of p21waf1/cip1 expression in acute myeloid leukemia cells
- gambogic acid induces heme oxygenase-1 through Nrf2 signaling pathway and inhibits NF-κB and MAPK activation to reduce inflammation in LPS-activated …
- gambogic acid induces mitochondria-dependent apoptosis by modulation of Bcl-2 and Bax in mantle cell lymphoma JeKo-1 cells
- gambogic acid induces Raji cell apoptosis in vitro and its mechanism
- gambogic acid induces the apoptosis an d arrests thec ycleo f human bladder cancer cells
- gambogic acid induces the apoptosis and autophagic cell death in human hepatoma cells
- gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
- gambogic acid inhibits angiogenesis through inhibiting PHD2–VHL–HIF-1α pathway
- gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1
- gambogic acid inhibits cell proliferation via suppressing epithelial growth factor receptor tyrosine phosphorylation in rat aortic smooth muscle cell
- gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma
- gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells
- gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells
- gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells.
- gambogic acid inhibits Hsp90 expressions in thiram-induced tibial dyschondroplasia
- gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP-1
- gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway
- gambogic acid inhibits malignant melanoma cell proliferation through mitochondrial p66shc/ROS-p53/Bax-mediated apoptosis
- gambogic acid Inhibits Melanoma through Regulation of miR‐199a‐3p/ZEB1 Signalling
- gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways
- gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways
- gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase …
- gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways
- gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis
- gambogic acid inhibits the catalytic activity of human topoisomerase IIα by binding to its ATPase domain
- gambogic acid inhibits the growth of osteosarcoma cells in vitro by inducing apoptosis and cell cycle arrest
- gambogic acid inhibits the growth of ovarian cancer tumors by regulating p65 activity
- gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
- gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways
- gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway
- gambogic acid is a novel anti-cancer agent that inhibits cell proliferation, angiogenesis and metastasis
- gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo
- gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
- gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system
- gambogic acid lysinate induces apoptosis in breast cancer MCF-7 cells by increasing reactive oxygen species
- gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
- gambogic acid mediates transferrin receptor-1 phosphorylation leading to jnk-dependant apoptosis
- gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway
- gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and-2
- gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting proliferation and inducing apoptosis
- gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF …
- gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells
- gambogic acid protects from endotoxin shock by suppressing pro-inflammatory factors in vivo and in vitro
- gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells
- gambogic acid regulates the migration and invasion of colorectal cancer via microRNA‑21‑mediated activation of phosphatase and tensin homolog
- gambogic acid reverses oxaliplatin resistance in colorectal cancer by increasing intracellular platinum levels
- gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings
- gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)
- gambogic acid sensitizes ovarian cancer cells to doxorubicin through ROS-mediated apoptosis
- gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression
- gambogic acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced …
- gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition
- gambogic acid suppresses colon cancer cell activity in vitro
- gambogic acid suppresses cytochrome P450 3A4 by downregulating pregnane X receptor and up-regulating DEC1 in human hepatoma HepG2 cells
- gambogic acid suppresses hypoxia‐induced hypoxia‐inducible factor‐1α/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3‐kinase …
- gambogic acid suppresses inflammation in rheumatoid arthritis rats via PI3K/Akt/mTOR signaling pathway
- gambogic acid suppresses pressure overload cardiac hypertrophy in rats
- gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
- gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway
- gambogic acid triggers vacuolization-associated cell death in cancer cells via disruption of thiol proteostasis
- gambogic acid, a natural product inhibitor of Hsp90
- gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells
- gambogic acid: A Caged Prenylated Garcinia Xanthone: Potent Anticancer Agent of Pharmaceutical Promise
- gambogic acid-encapsulated polymeric micelles improved therapeutic effects on pancreatic cancer
- gambogic acid-induced autophagy in nonsmall cell lung cancer NCI-H441 cells through a reactive oxygen species pathway
- gambogic acid‐induced degradation of mutant p53 is mediated by proteasome and related to CHIP
- gambogic acid-induced G 2 /M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC …
- gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment
- gambogic acid-loaded electrosprayed particles for site-specific treatment of hepatocellular carcinoma
- gambogic acid-loaded magnetic Fe3O4 nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor …
- gambogic acid-loaded PEG–PCL nanoparticles act as an effective antitumor agent against gastric cancer
- gambogic acid-loaded pH-sensitive mixed micelles for overcoming breast cancer resistance
- gambogic acid-loaded polymeric micelles for improved therapeutic effect in breast cancer
- General pharmacological properties, developmental toxicity, and analgesic activity of gambogic acid, a novel natural anticancer agent
- Global profiling of cellular targets of gambogic acid by quantitative chemical proteomics
- Hyaluronic acid-decorated redox-sensitive chitosan micelles for tumor-specific intracellular delivery of gambogic acid
- Hypoxia-induced resistance to cisplatin-mediated apoptosis in osteosarcoma cells is reversed by gambogic acid independently of HIF-1α
- Identification and quantitative determination of a major circulating metabolite of gambogic acid in human
- Identification of gambogic acid metabolites in rat bile by liquid chromatography-tandem mass spectrometry-ion trap-time-of-flight
- Improved druggability of gambogic acid using core–shell nanoparticles
- Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles
- Inclusion complex from cyclodextrin-grafted hyaluronic acid and pseudo protein as biodegradable nano-delivery vehicle for gambogic acid
- Induction of programmed erythrocyte death by gambogic acid
- Inhibition effect of gambogic acid on MUTZ-1 cell line and its possible mechanism
- Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study
- Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells
- Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference
- Inhibition of Murine Macrophage Inwardly Rectifying Kir2. 1 Channels by gambogic acid
- Inhibition of α4 integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
- Interaction between gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells
- Involvement of E-cadherin/AMPK/mTOR axis in LKB1-induced sensitivity of non-small cell lung cancer to gambogic acid
- Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis
- Involvement of RECK in gambogic acid induced anti‐invasive effect in A549 human lung carcinoma cells
- Involvement of Regulations of Nucleophosmin and Nucleoporins in gambogic acid‐Induced Apoptosis in Jurkat Cells
- Isolation and structure of neo-gambogic acid from Gamboge (Garcinia hanburryi)
- Magnetic and CD44 receptor dual targeting redox-responsive polymeric micelle for precise delivery of gambogic acid to triple-negative breast cancer
- Mechanism of gambogic acid-induced apoptosis in Raji cells
- Mechanisms of gambogic acid-induced apoptosis in non-small cell lung cancer cells in relation to transferrin receptors
- Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes
- Metabolism of gambogic acid in rats: a rare intestinal metabolic pathway responsible for its final disposition
- Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid‐induced apoptosis through down‐regulation of EZH 2 expression by miR‐101
- Michael acceptor in gambogic acid—Its role and application for potent antitumor agents
- Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in …
- Modified chitosan derivative micelle system for natural anti-tumor product gambogic acid delivery
- Molecular formula and identity of β-guttiferin and α-gambogic acid
- Molecular targets of gambogic acid in cancer: recent trends and advancements
- Multifunctional effects of Cys–CdTe QDs conjugated with gambogic acid for cancer cell tracing and inhibition
- Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G 0/G 1 cell cycle arrest in cervical, ovarian, and …
- Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G₀/G₁ cell cycle arrest in cervical, ovarian, and …
- Nanomedicine-based combination of gambogic acid and retinoic acid chlorochalcone for enhanced anticancer efficacy in osteosarcoma
- Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
- Nanoparticles with optimal ratiometric co-delivery of docetaxel with gambogic acid for treatment of multidrug-resistant breast cancer
- New targets for the antitumor activity of gambogic acid in hematologic malignancies
- Next-Generation Noncompetitive Nanosystems Based on gambogic acid: In Silico Identification of Transferrin Receptor Binding Sites, Regulatory Shelf Stability, and …
- N-octyl-N-arginine-chitosan (OACS) micelles for gambogic acid oral delivery: preparation, characterization and its study on in situ intestinal perfusion
- N-octyl-N-arginine-chitosan micelles for gambogic acid intravenous delivery: characterization, cell uptake, pharmacokinetics, and biodistribution
- Novel long-circulating liposomes consisting of PEG modified β-sitosterol for gambogic acid delivery
- Optimization of Extracting Process of Neo-gambogic acid [J]
- Optimization of Extraction Process of gambogic acid [J]
- Optimization of the formulation of gambogic acid nanosuspensions by the central composite design-response surface methodology
- Optimizing extraction process of neo-gambogic acid from gamboge by orthogonal test [J]
- PEG prodrug of gambogic acid: Amino acid and dipeptide spacer effects
- PEG–PLGA–PLL nanoparticles in combination with gambogic acid for reversing multidrug resistance of K562/A02 cells to daunorubicin
- Pharmacokinetics and Tissue Distribution Study of gambogic acid and gambogic acid Nanosuspension in Mice by UHPLC–MS/MS
- Pharmacokinetics of gambogic acid in rats
- Pharmacokinetics, tissue distribution and excretion of gambogic acid in rats
- PhaseⅠhuman tolerability trial of gambogic acid
- Pluronic F68-linoleic acid nano-spheres mediated delivery of gambogic acid for cancer therapy
- Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer
- Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells
- Potent anti-inflammatory and antiproliferative effects of gambogic acid in a rat model of antigen-induced arthritis
- Preparation, physical properties, and stability of gambogic acid-loaded micelles based on chitosan derivatives
- Preparative separation of gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography
- Progress in the Effect of Anti-tumor Molecular Targets of gambogic acid [J]
- Protective role of gambogic acid in experimental pulmonary fibrosis in vitro and in vivo
- Proteomic analysis revealed the important role of vimentin in human cervical carcinoma HeLa cells treated with gambogic acid
- Proteomic and bioinformatic analyses of possible target-related proteins of gambogic acid in human breast carcinoma MDA-MB-231 cells
- Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma
- Quantitative cardiotoxicity assessment of gambogic acid using multiple cellular phenotype analysis
- Radioiodinated of gambogic acid and its biodistribution in mice
- Rational Design of GO-Modified Fe3O4/SiO2 Nanoparticles with Combined Rhenium-188 and gambogic acid for Magnetic Target Therapy
- Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells
- Redox-responsive polymeric micelles formed by conjugating gambogic acid with bioreducible poly (amido amine) s for the co-delivery of docetaxel and MMP-9 …
- Regulation of gambogic acid on hERG potassium channel protein of K562 leukemia cells [J]
- Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells
- Research progress of gambogic acid as active ingredient of traditional Chinese medicine (TCM) gamboge
- Research progress of gambogic acid in tumor.
- Reversal effect of gambogic acid on multidrug resistance of K562/A02 cell line
- Role of chloride channels in gambogic acid-induced apoptosis of poorly differentiated nasopharyngeal carcinoma cells
- Role of gambogic acid and NaI131 in A549/DDP cells
- Role of gambogic acid in Chemosensitization of Cancer
- ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid
- Screening for natural compounds with anticancer activity in colon cancer cells identifies cytotoxic gambogic acid analogues
- Selective anti-proliferative effect of an anti-transferrin receptor IgG3-avidin fusion protein and gambogic acid in a panel of hematopoietic malignant cell lines
- Silencing pyruvate kinase M2 sensitizes human prostate cancer PC3 cells to gambogic acid-induced apoptosis
- Simultaneous determination and pharmacokinetic study of gambogic acid and gambogenic acid in rat plasma after oral administration of Garcinia hanburyi extracts …
- Single‐walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells
- Single-walled carbon nanotube and graphene: Nano-delivery of gambogic acid increases its cytotoxicty in various cancer cells
- Solubility measurement and RESOLV-assisted nanonization of gambogic acid in supercritical carbon dioxide for cancer therapy
- Specific and slow inhibition of the kir2. 1 K+ channel by gambogic acid
- Spectacular modification of gambogic acid on microwave irradiation in methanol: Isolation and structure identification of two products with potent anti-tumor activity
- Stability and cytotoxicity of gambogic acid and its derivative, gambogoic acid
- Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation
- Structure elucidation of metabolites of gambogic acid in vivo in rat bile by high-performance liquid chromatography–mass spectrometry and high-performance liquid …
- Structure-activity relationship of gambogic acid
- Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity
- Studies on Chemical Structure Modification and Structure Activity Relationship of Derivatives of gambogic acid at C (39)
- Studies on Chemical‐Structure Modification and Structure Activity Relationship of gambogic acid Derivatives at Carbon (34)
- Studies on gambogic acid (IV): Exploring structure–activity relationship with IκB kinase-beta (IKKβ)
- Studies on lactoferrin nanoparticles of gambogic acid for oral delivery
- Studies on preparation and stability of human serum albumin nanoparticles containing gambogic acid
- Studies on the toxicity of gambogic acid in rats
- Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles
- Study on gambogic acid-loaded Polylacticacid Nanoparticles
- Study on gambogic acid-loaded Polylacticacid Nanoparticles [J]
- Study on intestinal absorption kinetics of gambogic acid in rats
- Study progress on anti-tumor mechanism of gambogic acid [J]
- Subcellular localization and activity of gambogic acid
- Suppression of APC production during apoptosis of human colorectal cancer cell line SW480 induced by gambogic acid [J]
- Suppression of NF-κB signaling and P-glycoprotein function by gambogic acid synergistically potentiates adriamycin-induced apoptosis in lung cancer
- Synergetic effect of functional cadmium–tellurium quantum dots conjugated with gambogic acid for HepG2 cell-labeling and proliferation inhibition
- Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines
- Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma
- Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells
- Synergistic effect of magnetic nanoparticles of Fe3O4 with gambogic acid on apoptosis of K562 leukemia cells
- Synthesis and antiangiogenic activity of novel gambogic acid derivatives
- Synthesis and antitumor activities of structure-related small molecular compounds of gambogic acid
- Synthesis and anti-tumor activity of NO-donating derivatives of gambogic acid
- Synthesis and Anti‐tumor Evaluation of B‐ring Modified Caged Xanthone Analogues of gambogic acid
- Synthesis and Anti-tumor Evaluation of Nitrile-Containing gambogic acid Derivatives
- Synthesis and Anti‐tumor Evaluation of Novel C‐37 Modified Derivatives of gambogic acid
- Synthesis and biological evaluation of novel derivatives of gambogic acid as anti-hepatocellular carcinoma agents
- Synthesis and evaluation of gambogic acid derivatives as antitumor agents. Part III
- Synthesis of caged 2, 3, 3a, 7a-tetrahydro-3, 6-methanobenzofuran-7 (6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid
- Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery
- Targeting renal cell carcinoma with gambogic acid in combination with sunitinib in vitro and in vivo
- The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo
- The constitution of gambogic acid
- The growth inhibitory effect of gambogic acid on pancreatic cancer cells
- The natural compound gambogic acid radiosensitizes nasopharyngeal carcinoma cells under hypoxic conditions
- The natural interaction between gambogic acid and oxaliplatin and its probably mechanism
- The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
- The Noncompetitive Effect of gambogic acid Displaces Fluorescence-Labeled ATP but Requires ATP for Binding to Hsp90/HtpG
- The nuclear export of TR3 mediated gambogic acid-induced apoptosis in cervical cancer cells through mitochondrial dysfunction
- The regulation of neo-gambogic acid on miRNAs for epithelial-mesenchymal transition and drug-resistance of cervical cancer
- THERAPEUTIC POTENCIAL OF gambogic acid AND SILIBININ IN ACUTE MYELOBLASTIC LEUKEMIA-IN VITRO STUDIES: PB1708
- Therapeutic Potential of gambogic acid and Silibinin in Acute Myeloblastic Leukemia–in vitro studies
- Therapeutic potential of gambogic acid, a caged xanthone, to target cancer
- Titania-coated gold nanorods as an effective carrier for gambogic acid
- Toxicological studies of gambogic acid and its potential targets in experimental animals
- Transcriptional Analysis of the Effects of gambogic acid and Neogambogic acid: Inhibition of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus
- Triphenylphosphonium-modified poly (ethylene glycol)-poly (ε-caprolactone) micelles for mitochondria-targeted gambogic acid delivery
- Tumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer
- UHPLC‐MS method for determination of gambogic acid and application to bioavailability, pharmacokinetics, excretion and tissue distribution in rats
- UNC119 mediates gambogic acid-induced cell-cycle dysregulation through the Gsk3β/β-catenin pathway in hepatocellular carcinoma cells
- Viability inhibition effect of gambogic acid combined with cisplatin on osteosarcoma cells via mitochondria-independent apoptotic pathway
- Water-soluble gambogic acid PEGylated prodrugs: synthesis, characterization, physicochemical properties and in vitro hydrolysis
- α-Mangostin and gambogic acid as potential inhibitors of the p53–MDM2 interaction revealed by a yeast approach
