IKK

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  1. … -activated protein kinase kinase kinase 3 (MEKK3) is required for lysophosphatidic acid (LPA)-mediated optimal i [kappa] B kinase [beta](IKK [beta])/nuclear factor …
  2. … -induced expression of iNOS and COX-2 in BV2 murine microglial cells: possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling …
  3. … -insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK …
  4. … ) stimulates matrix mentalloproteinase-9 (MMP-9) production in cultured human chorion trophoblast cells through TNF alpha receptor 1 signalling to IKK beta, ERK1/2 …
  5. … 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1–dependent capillary-like structure formation: role of the IKK/NF-κB pathway
  6. … acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB
  7. … and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway”[Biochem. Pharmacol …
  8. … and the beautiful: A small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway
  9. … antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IκB/NF-κB …
  10. … as a target to increase apoptosis in primary mediastinal B-cell lymphoma (PMBL): Results of studies with rituximab (RTX), bortezomib (BTZ) and small molecule IKK …
  11. … attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways
  12. … between apoptosis in primary mediastinal B-cell lymphoma (PMBL) and NF-# 954; B Pathway Blockade: Bortezomib (BTZ), small molecule IKK inhibitor ML120B and …
  13. … cascade leading to apoptosis.) The anti-inflammatory phenolic curcumin from Curcuma species (turmeric)(Zingiberaceae) inhibits the IB kinase (IKK) and thus inhibits …
  14. … Conditioning and Ventilation held in Hanover for the first time: Air conditioning systems made in the Far East challenge traditional systems; IKK 2001-22. Internationale …
  15. … deacetylase inhibitors SAHA and NVP-LAQ824 is enhanced by interrupting NF-kappaB activation through a mechanism involving inhibition of IKK-mediated RelA/p65 …
  16. … disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced …
  17. … from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and …
  18. … growth factor-2 15-LOX, 15-lipoxygenase receptor tyrosine kinase LPS, lipopolysaccharide iGlu-R, inhibitory glutamate receptor LT, leukotriene IKK, inhibitor B kinase …
  19. … Impaired migration and proliferation of bone marrow-derived mesenchymal stem cells from patients with systemic lupus erythematosus were mediated by IKK-β
  20. … in this paper: ApoE, apolipoprotein E; BAE, bovine aortic endothelial; Coll, collagen; FG, fibrinogen; FN, fibronectin; IHC, immunohistochemistry; IKK, IκB kinase; LN …
  21. … Increases in Apoptosis in Primary Mediastinal B-Cell Lymphoma (PMBL) and NF-κB Pathway Blockade: Bortezomib (BTZ), Small Molecule IKK Inhibitor ML120B and …
  22. … inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK …
  23. … low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF‑κB pathway
  24. … mortality and district characteristics (IKK) of the TUeV Rheinland; Das Informationssystem ueber Krebsmortalitaet und Kreischarakteristika (IKK) des TUeV Rheinland
  25. … of Ethanolic Extract of Pericarps of Mangosteen (Garcinia mangostana Linn.) on WiDr Cells and Interaction Study of Alpha-mangosteen to IKK and VEGF Based on …
  26. … of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways
  27. … of the NF-κ B pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKK α
  28. … oxide level in tomato regulated by a mammalian IKK/NF-κB like signaling pathway? Is nitric oxide level in tomato regulated by a mammalian IKK/NFκB-like signaling …
  29. … Pathways Regulating Hepatic Apolipoprotein B100 Production: Roles of Mitogen-activated Protein Kinases (MAPKs) and Inhibitor of NFkappaB Kinase (IKK) …
  30. … pylori Induction in Gastric Mucosal Prostaglandin and Nitric Oxide Generation Is Dependent on MAPK/ERK-Mediated Activation of IKK-β and cPLA2 …
  31. … the DKV planner’s forum at the IKK 2000; Integration lufttechnischer Systemloesungen in die Gebaeudeautomation. Beitrag vom DKV-Planerforum waehrend der IKK …
  32. … the solution structure of IκB kinase (IKK) subunit γ and its interaction with kaposi sarcoma-associated herpes virus flice-interacting protein and IKK subunit β by EPR …
  33. 129. OVARIAN PHENOTYPE OF THE IKK CONDITIONAL KNOCKOUT MOUSE
  34. 147: Inhibitory kappa B kinase (IKK) inhibition attenuates infarct size in a murine model of myocardial ischemia-reperfusion
  35. 15‐Deoxy‐Δ12,14‐prostaglandin J2 inhibits IL‐1β‐induced IKK enzymatic activity and IκBα degradation in rat chondrocytes through a PPARγ‐independent pathway
  36. 20-HETE Activates Endothelial ACE via an IKK/NF-kB Dependent Pathway
  37. 20-SOLA, a Novel Water Soluble 20-HETE Antagonist, Reduces Blood Pressure Through Regulation of Vascular ACE Expression via an IKK Dependent Pathway
  38. 241 Tnf-α Induction of Infant Murine Brain Inflammation Via IKK/Nf Kappa B Signalling: A Potential Model for Paediatric Neuroinflammation
  39. 3, 5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β
  40. 3D‐QSAR Studies on a Class of IKK‐2 Inhibitors with GALAHAD Used to Develop Molecular Alignment Models
  41. 3D‐QSAR Study of Pyridine Derivates as IKK‐2 Inhibitors
  42. 4-Hydroxyestradiol induces neoplastic transformation of human breast epithelial cells by activating IKK-NF-κB signaling: possible involvement of reactive oxygen …
  43. 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase
  44. 57: Pivotal role of the IKK-related kinase IKK epsilon to modulate IL29 or type I IFN induction during hepatitis C virus infection
  45. A dominant function of IKK/NF-κB signaling in global lipopolysaccharide-induced gene expression
  46. A feedforward loop of NLRC5 (de) ubiquitination keeps IKK–NF-κB in check
  47. A key mediator, PTX3, of IKK/IκB/NF-κB exacerbates human umbilical vein endothelial cell injury and dysfunction
  48. A Kinase Upstream of IKK
  49. A negative feedback loop between miR‐200b and the nuclear factor‐κB pathway via IKBKB/IKK‐β in breast cancer cells
  50. A new role for IKK-α in hepatitis C virus-induced lipogenesis.
  51. A Novel IKK Inhibitor IMD-0560: Suppresses Chronic Remodeling after Myocardial Ischemia
  52. A Novel IKK Inhibitor Prevents Progression of Neointimal Formation After Arterial Injury in Mice
  53. A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice
  54. A novel IKK inhibitor suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration
  55. A novel role for IκB kinase (IKK) α and IKKβ in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae
  56. A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma …
  57. A novel, highly selective, tight binding IκB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-κB …
  58. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation
  59. A recurrent deletion in the ubiquitously expressed NEMO (IKK-γ) gene accounts for the vast majority of incontinentia pigmenti mutations
  60. A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1β-stimulated synovial fibroblasts
  61. A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
  62. A Specific IKK Inhibitor Suppresses Experimental Autoimmune Myocarditis in Rats
  63. A TNF &alphaA-responsive kinase activity may play a key role in IKK activation.
  64. A Truncated Form of IKKa Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer
  65. A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
  66. A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
  67. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFα and IL-1β
  68. A20-binding inhibitor of nuclear factor-B (NF-B)-2 (ABIN-2) is an activator of inhibitor of NF-B (IB) kinase (IKK)-mediated NF-B transcriptional activity
  69. AB0601 Anti-arthritis effects of (E)-2, 4-bis (P-hydroxyphenyl)-2-butenal through inhibition of IKK-beta activity
  70. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
  71. Abstract A41: The ASK1/IKK signaling axis mediates crosstalk between inflammation and apoptosis
  72. Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction
  73. Abstract B71: Chemosensitization to bleomycin conferred by a constitutive activation of IKK pathway in viral FLIP expressing cells
  74. Abstract LB-144: I-kappa-B kinase (IKK) ε expression in pancreatic ductal adenocarcinoma
  75. Abstract LB-206: A novel scaffold that targets the IKK complex
  76. Abstract P1-01-11: Nuclear immunohistochemical IKK-εexpression in flat epithelial atypia (FEA) of the breast: A predictor of ipsilateral ADH, in-situ or invasive …
  77. Abstract P5-05-10: EIA-Induced PP2A Expression Prevents β-Trcp Mediated FOXO3a Degradation and Enhances Chemosensitization by Inhibiting TAK1/IKK …
  78. Abstract# 1196: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK# 945; pathway
  79. Abstract# 1486: E1A-induced PP2A expression prevents# 946; TrCP-mediated FOXO3a degradation and enhances chemosensitization by inhibiting TAK1/IKK …
  80. Abstract# 1790: Different roles of IKK alpha and IKK beta on NF-kB pathway in mantle cell lymphoma and diffuse large B-cell ympoma
  81. Abstract# 441: TRAF2 phosphorylation at Ser-55 inhibits stress-induced cell death by promoting prolonged IKK activation
  82. Abstract# 4700: p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IKK inhibitor BMS-345541
  83. Abstract# 4958: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK# 945; pathway
  84. Abstract# 5050: 4-Hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells through ROS-mediated activation of IKK
  85. Abstract# 5269: TRAF2 suppresses IKK activity and inhibits TNFa-induced cell death independent of NF-kB activation
  86. Abstract# 5271: PKC-iota associates and phosphorylates IKK-# 945;/# 946; in breast cancer cell
  87. Abstract# 5488: IKK inhibitor Bay 11-7082 induces necrotic cell death in pre-B ALL cells
  88. Abstract# 5672: The role of IKK# 946;/TSC1 regulation in tumorigenesis and insulin resistance
  89. Accumulation of phosphorylated IκBα and activated IKK in nodes of Ranvier
  90. Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling
  91. Activation mechanisms of endothelial NF-κB, IKK, and MAP kinase by tert-butyl hydroperoxide
  92. Activation of a Subset of Genes by IFN-γ Requires IKKβ but Not Interferon-Dependent Activation of NF-κB
  93. Activation of G-protein-coupled estrogen receptor inhibits the migration of human nonsmall cell lung cancer cells via IKK-β/NF-κB signals
  94. Activation of IKK by thymosin α1 requires the TRAF6 signalling pathway
  95. Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
  96. Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice
  97. Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells
  98. Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin
  99. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
  100. Activation of the IκBα kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase …
  101. Activation of the virus-induced IKK/NF-kB signaling axis is critical for the replication of HCMV in quiescent cells
  102. Activation of the virus‐induced IKK/NF‐κB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells
  103. Active nuclear IKK correlates with metastatic risk in cutaneous squamous cell carcinoma
  104. Activity of bortezomib, a proteasome inhibitor, in breast cancer cells: Association with negative estrogen receptor and IKK/NF-κB expression
  105. Adenovirus mediated gene transfer of mutated IKK and IκBα reveal NF-κB dependent as well as independent pathway of HAS1 activation
  106. Adenovirus-mediated IKK β KA expression sensitizes prostate carcinoma cells to TRAIL-induced apoptosis
  107. Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB/PTEN …
  108. Advances in targeting IKK and IKK-related kinases for cancer therapy
  109. Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK
  110. Akt/IKK [alpha]/Vav1 Signaling in Endothelial Cell Survival and Angiogenesis
  111. Alpha-lipoic acid inhibits TNF-α induced NF-κB activation through blocking of MEKK1–MKK4–IKK signaling cascades
  112. Altered TAB1: IKK Interaction Promotes TGF-β-Mediated NF-κB Activation During Breast Cancer Progression
  113. Amelioration of Arthritis by Intraarticular Dominant Negative IKKβ Gene Therapy Using Adeno-Associated Virus Type 5
  114. Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure–activity relationship
  115. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
  116. Angiogenin mediates immune modulation and antiinflammatory reaction attenuating protein kinase IKK-ε in human corneal fibroblast cells
  117. Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis
  118. Anthrax lethal toxin enhances I kappa B kinase (IKK) activation and differentially regulates pro-inflammatory genes in human endothelium (135.3)
  119. Anti-inflammatory effects of IKK inhibitor XII, thymulin, and fat-soluble antioxidants in LPS-treated mice
  120. Anticancer agent CHS 828 suppresses nuclear factor‐κB activity in cancer cells through downregulation of IKK activity
  121. Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells
  122. Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition.
  123. Apoptotic role of IKK in T-ALL therapeutic response
  124. Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
  125. Aspirin inhibits IKK-β-mediated prostate cancer cell invasion by targeting matrix metalloproteinase-9 and urokinase-type plasminogen activator
  126. Association of a Network of Interferon-Stimulated Genes with a Locus Encoding a Negative Regulator of Non-conventional IKK Kinases and IFNB1
  127. Association of the adaptor TANK with the IκB kinase (IKK) regulator NEMO connects IKK complexes with IKKε and TBK1 kinases
  128. Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK …
  129. ATM is required for IκB kinase (IKK) activation in response to DNA double strand breaks
  130. ATM-and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
  131. ATM-dependent nuclear accumulation of IKK-α plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin
  132. ATP alters IKK-2 inhibitor affinity for IKK2 enzyme and reveals non-equivalent inhibitor binding sites
  133. ATS Abstract: IKK-ß Is Required For Rhinovirus Induced IFN-ß, IFN-» And Pro-inflammatory Cytokine Production In Vitro And In Vivo
  134. Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-γ)
  135. Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL
  136. Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway
  137. BAG3 is required for IKK α nuclear translocation and emergence of castration resistant prostate cancer
  138. Bcl3 phosphorylation by Akt, Erk2, and IKK is required for its transcriptional activity
  139. Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK
  140. Benzoxathiolone LYR-64 inhibits NF-kB activation via IKK complexin LPS-stimuated macrophages RAW 264. 7
  141. Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-κB, u-PA and MMP-2 and …
  142. Betafectin immunomodulator increases the activities of JNK and IKK kinases and increases the nuclear translocation of AP-1 in macrophage cells.
  143. BIOCHEMICAL CHARACTERIZATION OF SUPPRESSOR OF IKK-ε AND NAK-ASSOCIATED PROTEIN 1
  144. Biochemical Properties of IKK and Bcl3
  145. Bioinformatics Predictions of IKK Related Proteins Binding Long Non-Coding RNAs
  146. Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications
  147. Biomechanical signals inhibit IKK activity to attenuate NF‐κB transcription activity in inflamed chondrocytes
  148. Bortezomib Increases IL-8 Expression in Ovarian Cancer Cells Through IKK and EGR-1 Pathways
  149. Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components
  150. Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1
  151. C-Terminal Serine Rich Region of IKK– Interacts with Bfl-1, a Homologue of Bcl-2
  152. C70 THE NEXT NEW THERAPEUTIC TARGET? TRANSLATIONAL STUDIES OF COPD THERAPIES: The Effect Of An Ikgr; b-Kinase-[Beta](IKK [Beta]) Inhibitor On …
  153. Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-κB activity in LPS-stimulated mouse peritoneal …
  154. Caffeic acid regulates LPS-induced NF-κB activation through NIK/IKK and c-Src/ERK signaling pathways in endothelial cells
  155. Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure
  156. Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells
  157. CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts
  158. CFC replacement in the focus of attention at the IKK’91 in Essen. IKK 91 in Essen im Zeichen der FCKW-Substitution
  159. Characterization of the bovine IκB kinases (IKK) α and IKKβ, the regulatory subunit NEMO and their substrate IκBα
  160. Characterization of the IKK Signaling Complex
  161. Characterization of the inhibitor of kappaB kinase (IKK) complex in granulosa cell tumors of the ovary and granulosa cell tumor-derived cell lines
  162. Chemosensitization in non‐small cell lung cancer cells by IKK inhibitor occurs via NF‐κB and mitochondrial cytochrome c cascade
  163. Chlamydia pneumoniae activates IKK/IκB-mediated signaling, which is inhibited by 4-HNE and following primary exposure
  164. Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK
  165. cIAP2 negatively regulates proliferation and tumourigenesis by repressing IKK activity and maintaining p53 function
  166. Ciglitazone ameliorates lung inflammation by modulating the IKK/NF-κB pathway following hemorrhagic shock
  167. CIGLITAZONE REDUCES NF-κB ACTIVITY BY INHIBITING IKK IN HEMORRHAGIC SHOCK.: 58
  168. Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates …
  169. CITED2 modulates metastatic ability through effects on IKK-alpha in breast cancer cells
  170. Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression
  171. Clinical study on the relationship between the activation of the IKK-IκB-NFκB pathway and insulin resistance
  172. Cloning and characterization of an IKK homologue from pearl oyster, Pinctada fucata
  173. Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-κB signaling pathway
  174. Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-κB signal …
  175. Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons
  176. Collagen and prostaglandin E2 regulate aromatase expression through the PI3K/AKT/IKK and the MAP kinase pathways in adipose stromal cells
  177. Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IκB kinase-2 (IKK-2) target safety and efficacy
  178. Complete Reconstitution of Human IκB Kinase (IKK) Complex in Yeast ASSESSMENT OF ITS STOICHIOMETRY AND THE ROLE OF IKKγ ON THE COMPLEX …
  179. Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/p38MAPK pathways in RAW264. 7 …
  180. Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling
  181. Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells
  182. Conjugated linoleic acids produced by Lactobacillus dissociates IKK-γ and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells
  183. Connecting inflammation and cancer through the IKK-NF-κB nexus
  184. Constitutive Activation of NF-kappaB in Prostate Carcinoma Cells Through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
  185. Constitutive Activation of NF-Kb in Prostate Carcinoma Cells through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
  186. Constitutive activation of TAK1 by HTLV-1 tax-dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-κB
  187. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ …
  188. Context-dependent regulation of autophagy by IKK-NF-κB signaling: Impact on the aging process
  189. Control of canonical NF-κB activation through the NIK–IKK complex pathway
  190. Control of osteoclast activity and bone loss by IKK subunits: new targets for therapy
  191. Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I tax-mediated tumorigenesis
  192. Correlation between the signal pathway IKK/NF-? B and the anti-oxidant activity in asthma rats and the modulation of Ginkgo biloba extract
  193. Counter-regulation in the IKK family
  194. Crosstalk between the NF‐κB activating IKK‐complex and the CSN signalosome
  195. Crystal structure of a vFlip-IKKγ complex: insights into viral activation of the IKK signalosome
  196. Curcumin dually inhibits both mTOR and NF-κB pathways through a crossed PI3K/Akt/IKK signaling axis in adenoid cystic carcinoma
  197. Curcumin Treatment Suppresses IKK Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study
  198. Cutting edge: the IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
  199. Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death
  200. Cytosolic Hsp60 is involved in the NF-κB-dependent survival of cancer cells via IKK regulation
  201. Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the AKT/IKK pathway: Role of NF-κB and Bcl-2
  202. Daphnetin inhibits TNF‐α and VEGF‐induced angiogenesis through inhibition of the IKK s/IκBα/NF‐κB, Src/FAK/ERK 1/2 and Akt signalling pathways
  203. Davallia bilabiata Inhibits TNF-α-Induced Adhesion Molecules and Chemokines by Suppressing IKK/NF-kappa B Pathway in Vascular Endothelial Cells
  204. Dbl and the Rho GTPases activate NFκB by IκB kinase (IKK)-dependent and IKK-independent pathways
  205. De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-jB/IKK basal activity
  206. De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-κB/IKK basal activity
  207. Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
  208. Decreased IKK Signaling in Skeletal Muscle of Patients with Hyperglycemic Crisis.
  209. Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations
  210. Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK
  211. determine distinct IKK α Pleiotropic functions of TNF
  212. Dextran-g-lauric acid as IKK complex inhibitor carrier
  213. Differential IKK/NF-kB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells
  214. Differential IKK/NF-κB activity is mediated by TSC2 through mTORC1 in PTEN-null prostate cancer and tuberous sclerosis complex tumor cells
  215. Differential Requirement for the IKK
  216. Direct Phosphorylation of I kappa B by IKK [small alpha, Greek] and IKK [small beta, Greek]: Discrimination Between Free and NF-kappa B-Bound Substrate
  217. Direct, noncatalytic mechanism of IKK inhibition by A20
  218. Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)
  219. Discovery of 6-aryl-azabenzimidaoles that inhibit the TBK1/IKK-ε kinases
  220. Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques
  221. Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
  222. DISCOVERY OF NOVEL IKK-Β INHIBITOR BY STRUCTURAL MODIFICATIONS OF CHLORPROPAMIDE AND NATEGLINIDE
  223. Discovery of novel potent nuclear factor kappa‐B inhibitors (IKK‐β) via extensive ligand‐based modeling and virtual screening
  224. Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors
  225. Disrupting the inhibitory Kappa B kinase (IKK)-Aurora A axis in cancer
  226. Disruption of IκB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors
  227. Distinct activation mechanisms of NF-κB regulator inhibitor of NF-κB kinase (IKK) by isoforms of the cell death regulator cellular FLICE-like inhibitory protein (cFLIP)
  228. Distinct B subunits of PP 2A regulate the NF‐κB signalling pathway through dephosphorylation of IKK β, IκBα and RelA
  229. Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
  230. Diversity oriented synthesis and IKK inhibition of aminobenzimidazole tethered quinazoline-2, 4-diones, thioxoquinazolin-4-ones, benzodiazepine-2, 3, 5-triones …
  231. DMA, a Bisbenzimidazole, Offers Radioprotection by Promoting NFκB Transactivation through NIK/IKK in Human Glioma Cells
  232. Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways
  233. Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in Tax-mediated activation of IKK
  234. Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis
  235. Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
  236. Dynamic Characterization of the IKK: κBα: NFκB Negative Feedback Loop Using Real-Time Bioluminescence Imaging
  237. Dynamic interaction of stress granules, DDX3X, and IKK-α mediates multiple functions in hepatitis C virus infection
  238. E1A inhibition of radiation-induced NF-κB activity through suppression of IKK activity and IκB degradation, independent of Akt activation
  239. Effect and mechanism of IKK-2 receptor blocker on corneal stromal fibroblasts
  240. Effect and significance of anisodamine on I-kappaB kinase (IKK) in traumatic lung injury
  241. Effect of Collaterals-smoothing Drugs on Expressions of IκB-a and IKK-a in Sciatic Nerve of Diabetic Rats
  242. Effect of FK506 and Cyclosporin A on IκBα Degradation and IKK Pathway in Bronchial Epithelial Cells, Monocytes, Lymphocytes and Alveolar Macrophages
  243. Effect of IKK-2 Inhibitor on Local Th1 and Th2 Type Inflammation
  244. Effect of IKK-beta specific inhibitor PS1145 on NF-kappaB activity and apoptosis in prostate carcinoma cell lines
  245. Effect of Kuijieling decoction on proteins expression of IKK-alpha in colonic mucosa of ulcerative colitis model rats
  246. Effect of Rosiglitazone on Insulin Resistance and ROS. IKK Signaling Pathway in Vascular Endothelial Cells
  247. Effect of rosiglitazone on phosphorylation IKK and IκBα in the Heart of STZ Diabetic Rats [J]
  248. Effective suppression of pro‐inflammatory molecules by DHCA via IKK‐NF‐κB pathway, in vitro and in vivo
  249. Effects of a brief high-fat diet and acute exercise on the mTORC1 and IKK/NF-κB pathways in rat skeletal muscle
  250. Effects of IKK inhibitor PS1145 on NF-κ B function, proliferation, apoptosis and invasion activity in prostate carcinoma cells
  251. Effects of P-MAPA immunomodulator on Toll-like receptor 2, ROS, nitric oxide, MAPKp38 and IKK in PBMC and macrophages from dogs with visceral leishmaniasis
  252. Effects of Soothing Liver and Invigorating Spleen Recipes on the IKK-NF-B Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats
  253. Effects of TCDD upon IκB and IKK subunits localized in microsomes by proteomics
  254. El BUSINESS If IKK
  255. Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice
  256. EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-κB andMKK7/JNK …
  257. Endothelial cell injury and dysfunction induced by silver nanoparticles through oxidative stress via IKK/NF-κB pathways
  258. Endothelial IKK β Signaling is Required for Monocyte Adhesion under Laminar Flow Conditions
  259. Endothelial-specific Deletion of Inhibitor of Kappa-B Kinase-β (IKK-β)
  260. Energy calibration of the IKK fast chopper with 238U standards
  261. Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
  262. Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation
  263. Epstein–Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-κ B2 to p52 via an IKK γ/NEMO-independent signalling …
  264. ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK
  265. ERK is an anti-inflammatory signal that suppresses expression of NF-κB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells
  266. Erratum to” Discovery of novel and selective IKK-b serine-threonine protein kinase inhibitors. Part 1″-(Bioorg. Med. Chem. Lett. 13 (2003) 913)
  267. Etanercept Reverses Downregulation of Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha (IKK [alpha]) in Psoriasis
  268. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-κ B activation and proliferation in human head and neck …
  269. Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-B activation
  270. Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-κB activation
  271. Exploring Suppressor of IKK Epsilon’s Interaction with Cytoskeletal Proteins
  272. Expression and function of NIK‐and IKK 2‐binding protein (NIBP) in mouse enteric nervous system
  273. Expression and regulation of inducible IκB kinase (IKK-i) in human fibroblast-like synoviocytes
  274. Expression, purification and functional characterization of IκB kinase-2 (IKK-2) mutants
  275. Faculty, IKK
  276. FAF1 suppresses IκB kinase (IKK) activation by disrupting the IKK complex assembly
  277. Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes
  278. Fanconi anemia protein complex is a novel target of the IKK signalsome
  279. Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
  280. Fentanyl Suppresses the Survival of CD4+ T Cells Isolated from Human Umbilical Cord Blood through Inhibition of IKKs‐mediated NF‐κB Activation
  281. fibrosis) at 28-days post reperfusion, which was markedly reduced by the late administration of IKK16. Conclusion: The late inhibition of IKK may, therefore, have …
  282. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways
  283. Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-β kinase pathway
  284. FOXO 3 as a new IKK‐ε‐controlled check‐point of regulation of IFN‐β expression
  285. FoxO transcription factor is delocalized in CML patients by Bcr-Abl induced PI3K/AKT activation and IKK pathway and can be reactivated by Imatinib treatment
  286. FoxO Transcription Factor Is Delocalized in CML Patients by Bcr-Abl Induced PI3K/AKT Activation and IKK Pathway and Can Be Reactivated by Imatinib Treatment.
  287. Functional analysis of astroglial IKK/NF-KappaB signaling in brain development and homeostasis
  288. Functional Role of c-Src in IL-1–Induced NF-κB Activation: c-Src Is a Component of the IKK Complex
  289. GD2+ breast cancer stem cell growth is dependent on NFκB signaling and suppressed by the IKK inhibitor BMS345541 in vitro and in vivo
  290. Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis
  291. Ghrelin Suppression of Helicobacter pylori-Induced Gastric Mucosal Expression of iNOS is Mediated through the Inhibition of IKK-β Activation by cNOS …
  292. Gold compound auranofin inhibits IκB kinase (IKK) by modifying Cys-179 of IKKβ subunit
  293. GPx-1 Gene Delivery Modulates NFκB Activation Following Diverse Environmental Injuries Through a Specific Subunit of the IKK Complex
  294. GW26-e1432 Effect of Rosiglitazone on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
  295. GW26-e2212 Effect of Atorvastatin on IKK/NF-кB Pathway of Insulin Resistance in Vascular Endothelial Cells
  296. GW27-e0848 Effect of Celastrol on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
  297. H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-κB signal pathway
  298. hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex
  299. HDAC/IKK inhibition therapies in solid tumors.
  300. Heat shock treatment suppresses angiotensin II-induced activation of NF-κB pathway and heart inflammation: a role for IKK depletion by heat shock?
  301. Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated …
  302. Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage‐mediated chronic inflammation
  303. Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly
  304. Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE* 3-Leiden mice
  305. Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways
  306. High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction
  307. Hijacking of host cell IKK signalosomes by the transforming parasite Theileria
  308. Histone deacetylase (HDAC) inhibition induces IκB kinase (IKK)-dependent interleukin-8/CXCL8 expression in ovarian cancer cells
  309. Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
  310. Hit Identification of IKK-beta Natural Product Inhibitor
  311. Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors
  312. Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model
  313. Honokiol inhibits TNF-α-stimulated NF-κB activation and NF-κB-regulated gene expression through suppression of IKK activation
  314. Host and parasite-derived IKK activities direct distinct temporal phases of NF-κB activation and target gene expression following Toxoplasma gondii infection
  315. How NF-κB is activated: the role of the IκB kinase (IKK) complex
  316. HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination
  317. Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)
  318. HTLV-1 tax functions as a ubiquitin E3 ligase for direct IKK activation via synthesis of mixed-linkage polyubiquitin chains
  319. HTLV-1 tax induces formation of the active macromolecular IKK complex by generating Lys63-and Met1-linked hybrid polyubiquitin chains
  320. HTLV-1 Tax protein induces autophagy via IKK in human astroglioma cells: a protective mechanism against death receptor-mediated apoptosis (610.1)
  321. HTLV-1 Tax stimulates ubiquitin E3 ligase, ring finger protein 8, to assemble lysine 63-linked polyubiquitin chains for TAK1 and IKK activation
  322. Hyaluronan induces MMP-9 secretion through FAK-IKK/IκBα pathways and 17-AAG down-regulates these pathways in human glioma cells
  323. Hydrogen peroxide has opposing effects on IKK activity and I κ B α breakdown in airway epithelial cells
  324. Hyper activation of β‐catenin signalling induced by IKK ε inhibition thwarts colorectal cancer cell proliferation
  325. Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
  326. Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster
  327. I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin’s lymphoma
  328. Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-κB and JNK/p38 MAPK pathways
  329. Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the
  330. Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays
  331. Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity
  332. Identification of mutations in TRAPPC9, which encodes the NIK-and IKK-β-binding protein, in nonsyndromic autosomal-recessive mental retardation
  333. IDENTIFICATION OF NOVEL SUBSTRATE I-TRAF OF IKK-i KINASE
  334. Identification of plumericin from Himatanthus Sucuuba as a novel potent inhibitor of the NF-κB pathway directly targeting IKK-β
  335. IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)
  336. IKK Alfred, Crosby-house, 95, Bishopsgate-street
  337. IKK alpha coordinates with RAS to switch well-differentiated papillomas to poorly differentiated malignant carcinomas in skin
  338. IKK alpha induces angiogenesis
  339. IKK alpha play an inhibitory role in malignant skin tumor progression
  340. IKK and (Beta)-Catenin in Breast Cancer
  341. IKK and Caspases in Regulating Cell Shape
  342. IKK and Diabetic Nephropathy [J]
  343. IKK and NF‐κB‐mediated regulation of Claspin impacts on ATR checkpoint function
  344. IKK antagonizes activation-induced cell death of CD4+ T cells in aged mice via inhibition of JNK activation
  345. IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-κB activity
  346. IKK at the 580 revolutions the “down” run was made
  347. IKK biology
  348. IKK Capt. Gabriel J., 6, Belsize-park, Hampstead
  349. IKK Charles Henry, 51, King’s-road, Camden-town
  350. IKK connects autophagy to major stress pathways
  351. IKK cuts both ways in Huntington’s disease
  352. IKK Electric F40LW-RS-WMII at approximately 1000
  353. IKK epsilon Deficiency Exacerbates Inflammation in the Absence of an Interferon Response in Murine Arthritis by Delaying Neutrophil Apoptosis
  354. IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis
  355. IKK epsilon, STAT1, and IFIT2 define a novel innate immune effector pathway against West Nile virus infection
  356. IKK exceptional, viz. the temperature high and the air
  357. IKK expression as an immunohistochemical marker for diagnosis of high risk flat epithelial atypia (FEA) of the breast
  358. IKK Goes BAD
  359. IKK have not saved, and to bury them when
  360. IKK Henry Charles, 86, South-hill-park, Hampstead
  361. IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells
  362. IKK inhibition increases bortezomib effectiveness in ovarian cancer
  363. IKK inhibition prevents PM2. 5-exacerbated cardiac injury in mice with type 2 diabetes
  364. IKK inhibitor PS1145 increases sensitivity of pancreatic cancer cells to TRAIL-induced apoptosis.
  365. IKK inhibitor suppresses epithelial-mesenchymal transition and induces cell death in prostate cancer
  366. IKK inhibitory activities of imidazo [1, 2-a] pyrazine, imidazo [1, 2-a] quinoxaline, imidazo [1, 5-a] quinoxaline and pyrazolo [1, 5-a] quinoxaline derivatives.
  367. IKK interacts with rictor and regulates mTORC2
  368. IKK is a therapeutic target in KRAS-induced lung cancer with disrupted p53 activity
  369. IKK jar of the previous dayforgiven, if not for
  370. IKK kinase assay for assessment of canonical NF-κB activation in neurons
  371. IKK Links the Steroid Receptor Coactivator to Immune Responses
  372. IKK low much or how little it surprised
  373. IKK M.-What is memory aging the aging of? Developmental Psychology. 1978, 14
  374. IKK mediates ischemia-induced neuronal death
  375. IKK my passage-money is more than I can
  376. IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model
  377. IKK of ease, and little alle
  378. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
  379. IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors
  380. IKK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer
  381. IKK Phosphorylation, ICAM–1, and CD11a/LFA–1 Increases Are Correlated With VEGF–Induced Blood–Retinal Barrier Breakdown and Are Blocked by Triamcinolone …
  382. IKK Proverb,” that he who i
  383. IKK regulates the deubiquitinase CYLD at the postsynaptic density
  384. IKK regulation and human genetics
  385. IKK results are included AAAAA
  386. IKK SCienCe
  387. IKK Targets PI3K
  388. IKK that the fact was not suspected in his life
  389. IKK the night and the morrow in that disa
  390. IKK The North Central High School, Spökano
  391. IKK to British subjects, residing at Zan
  392. IKK to us, nor could it have influenced our
  393. IKK were entitled to protection against this system of
  394. IKK with ebonite is shown in the following
  395. IKK with Mr. E, Jones, Hibernian Schools, Liver.
  396. IKK yearly by government auditor, and pub
  397. IKK α represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the …
  398. IKK β in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5
  399. IKK β inhibitor identification: a multi-filter driven novel scaffold
  400. IKK β programs to turn on the GADD45α/MKK4/JNKs apoptotic cascade specifically via p50 NF-κB in arsenite response
  401. IKK β regulates endothelial thrombomodulin in a Klf2‐dependent manner
  402. IKK β-targeted anti-inflammatory activities of a butanol fraction of artificially cultivated Cordyceps pruinosa fruit bodies
  403. IKK-±: An Alternative Player In Inflammation-Induced Loss Of Muscle Oxidative Phenotype In COPD?
  404. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation
  405. IKK-2
  406. IKK-2 inhibitor TPCA-1 represses nasal epithelial inflammation in vitro.
  407. IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells
  408. IKK-2/NF-κB-DEPENDENT TRANSCRIPTION
  409. IKK-alpha PROTEIN, NUCLEIC ACID ENCODING THE SAME AND METHOD
  410. IKK-and NF-κB-mediated functions in carcinogenesis
  411. IKK-Beta Deletion Alleviates the Atherogenetic Effect of Intermittent Hypoxia Induced Macrophage Foam Cell Formation
  412. IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1
  413. IKK-dependent, NF-κB-independent control of autophagic gene expression
  414. IKK-epsilon contributes to the malignant progression of ovarian cancer
  415. IKK-Epsilon, a novel factor identified by proteomics, contributes to prostate cancer cell-induced osteoclast activity in vitro.
  416. IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2 COMPARATIVE ANALYSIS OF RECOMBINANT HUMAN IKK-i, TBK-1, AND IKK-2
  417. IKK-i signals through IRF3 and NFκB to mediate the production of inflammatory cytokines
  418. IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
  419. IKK-i/IKKϵ controls constitutive, cancer cell-associated NF-κB activity via regulation of Ser-536 p65/RelA phosphorylation
  420. IKK-IKB-NF-kB gene manipulations and polymorphisms in relation to susceptibility to different diseases
  421. IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen
  422. IKK-mediated signaling controls prostate tumor initiating cells
  423. IKK-NBD peptides exert anti-inflammation effect in rats after focal cerebral cortex ischemia/reperfusion via regulating c-rel [J]
  424. IKK-related genetic diseases: probing NF-κB functions in humans and other matters
  425. IKK-β inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches
  426. IKK-β links inflammation to obesity-induced insulin resistance
  427. IKK-β mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death
  428. IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1
  429. IKK-β Recombinant Adenovirus
  430. IKK-β/NF-κB p65 mediates p27Kip1 protein degradation in arsenite response
  431. IKK-γ is an essential regulatory subunit of the IκB kinase complex
  432. IKK-γ, GST-tagged, human recombinant, expressed in Sf9 cells
  433. IKK-ε coordinates invasion and metastasis of ovarian cancer
  434. IKK‐β‐mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury
  435. IKK? and synovial inflammation
  436. IKK? is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity
  437. IKK/NF-kappaB serving as essential components of the MAP kinase signal transduction pathway.
  438. IKK/NF-κB activation is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils
  439. IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
  440. IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
  441. IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance
  442. IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut
  443. IKK/NF-κB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors
  444. IKK/NF-κB signaling: balancing life and death–a new approach to cancer therapy
  445. IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
  446. IKK/NF-κB/Rel in Acute Pancreatitis and Pancreatic Cancer: Torments of Tantalus
  447. IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis
  448. IKK/nuclear factor-kappaB and oncogenesis: roles in tumor-initiating cells and in the tumor microenvironment
  449. IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells
  450. IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
  451. Improved Intraportal Islet Transplantation Outcome by Systemic IKK‐beta Inhibition: NF‐κB Activity in Pancreatic Islets Depends on Oxygen Availability
  452. in vivo Cardiac Gene Transfer of Dominant Negative IKK-beta Reduces Myocardial Inflammation, Apoptosis, and Infarction after Ischemia-Reperfusion Injury
  453. In Vivo Cardioprotection by Pitavastatin From Ischemic-reperfusion Injury Through Suppression of IKK/NF-κB and Upregulation of pAkt–e-NOS
  454. In Vivoandin VitroRecruitment of an IκBα-Ubiquitin Ligase to IκBα Phosphorylated by IKK, Leading to Ubiquitination
  455. Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation
  456. Inactivation of Bcl‐2 through IκB kinase (IKK)‐dependent phosphorylation mediates apoptosis upon exposure to 4‐hydroxynonenal (HNE)
  457. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation
  458. Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK-mediated activation of IKK-β and cPLA2: modulatory …
  459. Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF‐κB signal transduction pathway in astrocytes infected with Escherichia coli
  460. Inflammation and the IKK β/I κ B/NF-κ B axis in obesity-and diet-induced insulin resistance
  461. Influence of low level and long-term arsenic exposure to the phosphorylated protein kinase B as well as its downstream signal factor IKK, I-ΚB and NF-κB in HaCat …
  462. Influence of oleanolic acid pretreatment to the IKK/I-κB/NF-κB signaling pathway during rat’s HIRI [J]
  463. Influence of rosuvastatin calcium and telmisartan on the expressions of IKK, ROS of insulin resistance rat liver
  464. Influenza A virus‐encoded NS 1 virulence factor protein inhibits innate immune response by targeting IKK
  465. Information and communication platform for crisis management (IKK)
  466. Inhibition of canonical IKK/NF-kB signaling in Hepatitis B Virus surface antigen transgenic mice drastically increases HCC development due to dysregulated Unfolded …
  467. Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I‐κB kinase (IKK) inhibitors
  468. Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK …
  469. Inhibition of herpesvirus-induced HIV-1 replication by cyclopentenone prostaglandins: role of IκB kinase (IKK)
  470. Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel α-methylene-γ …
  471. Inhibition of IKK [Beta] ReversesInsulin Resistance’in Cultured Cells
  472. Inhibition of IKK activation, through sequestering NEMO, blocks PMMA‐induced osteoclastogenesis and calvarial inflammatory osteolysis
  473. Inhibition of IKK activity enhances cell cycle arrest through p53-dependent p21Cip/WAF1 activation.
  474. Inhibition of IKK down‐regulates antigen+ IgE‐induced TNF production by mast cells: a role for the IKK‐IκB‐NF‐κB pathway in IgE‐dependent mast cell activation
  475. Inhibition of IKK-2 by 2-[(aminocarbonyl) amino]-5-acetylenyl-3-thiophenecarboxamides
  476. Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation
  477. Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua)
  478. Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32
  479. Inhibition of IKK/NF-κB impairs glioma stem cell function
  480. Inhibition of IKK/NF-κB signaling enhances differentiation of mesenchymal stromal cells from human embryonic stem cells
  481. Inhibition of IL-6 Release in Vitro by in Vivo Administration of an IKK Inhibitor in Mice with Lung Fibrosis Induced by Poly I: C
  482. Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes
  483. Inhibition of IκB phosphorylation by a novel IKK inhibitor IMD-1041 attenuates myocardial dysfunction after infarction
  484. Inhibition of IκB Phosphorylation by a Novel IKK Inhibitor IMD-1041 Attenuates Myocardial Dysfunction After Infarction
  485. Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia
  486. Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation
  487. Inhibition of osteoblast functions by IKK/NF-κB in osteoporosis
  488. Inhibition of rosiglitazone on the expression of IKK-# beta# in the livers of rats with nonalcoholic steatohepatitis
  489. Inhibition of the canonical IKK/NFκB pathway sensitizes human cancer cells to doxorubicin
  490. Inhibition of the IKK pathway restores PI3-K activity in high-fat fed rodent skeletal muscles
  491. Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice
  492. Inhibition of the IKK/NF-κB pathway impairs glioma stem cell function
  493. Inhibition of the NF-κ B survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κ B essential modulator NEMO
  494. Inhibition of type I interferon production via suppressing IKK-gamma expression: a new strategy for counteracting host antiviral defense by influenza A viruses?
  495. Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1
  496. Inhibitor-κB Kinase (IKK) β Regulates LPS-induced TNF-α Production in Cardiac Myocytes Through Modulation of NF-κB p65 Subunit Phosphorylation
  497. Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90
  498. Insulin exerts anti-inflammatory effects through reduction of IKK/IκB/NF-κB pathway activation in septic rats
  499. Insulin Receptor and IRS-1 Co-immunoprecipitation with SOCS-3, and IKK?/? Phosphorylation are Increased in Obese Zucker Rat Skeletal Muscle
  500. Insulin resistance, inflammation, and the IKK/IκB/NF-κB pathway
  501. Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-κB signaling
  502. Integrating cell-signalling pathways with NF-κB and IKK function
  503. Integration of TNF-a Signaling: Crosstalk between IKK, JNK, and Caspases
  504. Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase 2 (IKK2, IKK-beta, IKBKB) and TRAF2 indicating a dose dependent regulatory …
  505. Interaction of vehicle and terrain results from 10 years research at IKK
  506. Interferon Regulatory Factors and the Atypical IKK-Related Kinases TBK1 and IKK-ε: Essential Players in the Innate Immune Response to RNA Virus Infection
  507. Interleukin-18 is a Potent Inducer of EMMPRIN Expression Both in vitro and in vivo, and Their Crosstalk Induces MMP9 Expression via PI3K-Akt-IKK-NF-κB …
  508. Intermittent hypoxia induces murine macrophage foam cell formation by IKK-β-dependent NF-κB pathway activation
  509. Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
  510. Intestinal carcinogenesis: IKK can go all the way
  511. Intestinal epithelial cells release CXCL-2 in response to lipopolysaccharide via NF-KB and IKK activation
  512. Investigating IKK dynamics in the NF-κB signalling pathway using X-machines
  513. Investigation on constitutive IKK activity in the axon initial segment
  514. Involvement of cAMP-and IKK-2-Dependent Signal Pathways in the Growth Capacity of Mesenchymal Progenitor Cells under the Influence of Basic Fibroblast Growth …
  515. Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
  516. Involvement of the ubiquitin‐like domain of TBK1/IKK‐i kinases in regulation of IFN‐inducible genes
  517. Iron causes interactions of TAK1, p21ras and PI3K in caveolae to activate IKK in hepatic macrophages
  518. IκB kinase (IKK) β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
  519. IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
  520. IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway
  521. IκB kinase-2-independent and-dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic
  522. IκB Kinases (IKK) and Diabetic Retinopathy
  523. JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action?
  524. Juncture of the cytoskeleton and innate immune signaling pathways: the role of Suppressor of IKK epsilon (SIKE)
  525. Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats
  526. Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
  527. Kinetic mechanisms of IκB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer
  528. kk IKK the Flatheads. TC Elliott (Oregon Historical Quarterly
  529. kkkk kkk tO 豎 in the IKK and protection of public health
  530. KSHV vFLIP binds to IKK-γ to activate IKK
  531. KSK5104, IKK-β Inhibitor for Treating Reumatoid Arthrotis
  532. LEVELS OF IL-10 ALTER NF-KAPPA B ACTIVATION THROUGH REGULATION OF I KAPPA KINASE (IKK) IN BOTH HUMAN AND MOUSE CELL TYPES: 273
  533. LF15‐0195 generates tolerogenic dendritic cells by suppression of NF‐κB signaling through inhibition of IKK activity
  534. Lin28B mediated IKK-β sustains the stemness of breast cancer stem cell via regulating Wnt/TCF4 and miR-34a/LEF1 signaling pathway
  535. Linoleic Acid Induces Expression of Monocyte Chemoattractant Protein 1 via PI3K, PKC, IKK, and NF-b Pathway in Retinal Pigment Epihelial Cells
  536. Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB
  537. Lipopolysaccharide-mediated Interferon Regulatory Factor Activation Involves TBK1-IKK-dependent Lys 63-linked Polyubiquitination and Phosphorylation of …
  538. Local administration of IKK small molecule inhibitor may enhance fracture healing in osteoporosis patient
  539. Local and Systemic IKK and NF-B Signaling Associated with Sjögren’s Syndrome Immunopathogenesis
  540. Local and systemic insulin resistance resulting from hepatic activation of IKK-ßand NF-? B.
  541. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
  542. Long-term incubation with proteasome inhibitors (PIs) induces IκBα degradation via the lysosomal pathway in an IκB kinase (IKK)-dependent and IKK-independent …
  543. Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-κB in endothelial cells
  544. LPS induces Rac1-dependent reactive oxygen species (ROS) formation and coordinates TNF-α secretion through IKK regulation of NF-kappa B
  545. LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
  546. LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex
  547. Lyn kinase controls TLR4-dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells
  548. Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor α-and interleukin-1β-induced IKK/NF-κB and JNK/AP-1 activation
  549. Maintenance of constitutive NF-κB activity by glycogen synthase kinase-3 and IKK in pancreatic cancer
  550. Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophages
  551. MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-κB-dependent proliferative advantage and resistance against FAS-induced cell death in …
  552. MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activation
  553. Marasmius oreades substances block NF-κB activity through interference with IKK activation pathway
  554. Mature T cells depend on signaling through the IKK complex
  555. Measurement of IKK activity in primary rat T cells: rapid activation and inactivation
  556. MECHANIMS OF GENE ACTIVATION BY PATHOGENIC AND INFLAMMATORY STIMULI THROUGH IKK AND NF-KB PATHWAYS: 177
  557. Mechanism of IKK activation by the Kaposi’s sarcoma-associated herpesvirus protein vFLIP and its cellular homologues
  558. Mechanism underlying IKK activation mediated by the linear ubiquitin chain assembly complex (LUBAC)
  559. Mechanisms by which the IKK-related Kinases Affect Energy Expenditure.
  560. Mechanisms of IKK/NF-κB dependent diabetes development
  561. Mechanisms of liver injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways
  562. MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection
  563. Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation
  564. Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK 𝛽 Action in a Fiber-Type Specific Manner
  565. Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation
  566. Methods for identifying and using IKK inhibitors
  567. Micrococci and peptidoglycan activate TLR2→ MyD88→ IRAK→ TRAF→ NIK→ IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8
  568. Migration and proliferation of human mesenchymai stem cells from patients with systemic lupus erythematosus mediated by IKK-β
  569. miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β
  570. miR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-β
  571. miR‐429 is involved in regulation of NF‐κBactivity by targeting IKK β and suppresses oncogenic activity in cervical cancer cells
  572. MiR‐503 targets PI3K p85 and IKK‐β and suppresses progression of non‐small cell lung cancer
  573. Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death
  574. Miyabenol A inhibits LPS-induced NO production via IKK/IκB inactivation in RAW 264.7 macrophages: possible involvement of the p38 and PI3K pathways
  575. MMP9 reinforces radiation-induced delayed invasion and metastasis of neuroblastoma through second-signaling positive feedback with NFκB via both ERK and IKK …
  576. Modulation of cellular IKK complexes by human Adenovirus Type 5
  577. Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 …
  578. Modulation of IKK/NF-B signaling iin pancreatic ß-cells induces diabetes
  579. Modulation of NF‐κB activation in Theileria annulata‐infected cloned cell lines is associated with detection of parasite‐dependent IKK signalosomes and disruption of …
  580. Modulation of nuclear factor-kb (NF-kb), IkB kinase (IKK) and inducible nitric oxide synthase (iNOS) via proinflammatory cytokines with adjuvant selenomethionine (Se …
  581. Modulation of the SMRT co-repressor by IKK: Requirement for NF-κB transcription and cell survival
  582. Molecular cloning and characterization of an IKK homologue from amphioxus (Branchiostoma belcheri)
  583. MOLECULAR CLONING, EXPRESSION ANALYSIS AND CHARACTERIZATION OF GRASS CARP IKK-BETA
  584. Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney
  585. Molecular mechanism of inhibitor of κ B kinase (IKK) complex activation by inducible phosphorylation and ubiquitination upon T cell receptor (TCR) …
  586. Multiple functions of the IKK-related kinase IKKε in interferon-mediated antiviral immunity
  587. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL’s in vitro transforming …
  588. Mutation of cysteine 46 in IKK-beta increases inflammatory responses
  589. Myosin motor Myo1c and its receptor NEMO/IKK-γ promote TNF-α–induced serine307 phosphorylation of IRS-1
  590. Myricetin attenuates lipopolysaccharide‐stimulated activation of mouse bone marrow‐derived dendritic cells through suppression of IKK/NF‐κB and MAPK signalling …
  591. Myricetin attenuates lipopolysaccharideâ stimulated activation of mouse bone marrowâ derived dendritic cells through suppression of IKK/NFâ κB and MAPK …
  592. Natural Molecules as IKK α/β Inhibitors useful in the Treatment of Inflammation
  593. Negative feedback loops: nutrient starvation employs a new tr (IKK) to inhibit PI3K
  594. NEMO (IKK [gamma]) Mutation Can Be Associated With Opportunistic Infection Without Impairing TLR Function
  595. NEMO binding domain of IKK‐2 encompasses amino acids 735–745
  596. NEMO/IKK γ regulates an early NF-κ B-independent cell-death checkpoint during TNF signaling
  597. Neuroprotective potential of the NF-κB inhibitor peptide IKK-NBD in cerebral ischemia-reperfusion injury
  598. New functions of NEMO, the regulatory subunit of IKK
  599. New IKK inhibitors: Synthesis of new imidazo [1, 2-a] quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors
  600. NF-kappaB targeting by way of IKK inhibition sensitizes lung cancer cells
  601. NF-kappaB/IKK-2 Signalling Is Not Required For Cigarette Smoke-Induced Airway Inflammation
  602. NF-κB and IKK as Key Mediators of Inflammation and Oncogenic Progression
  603. NF-κB and IKK as therapeutic targets in cancer
  604. NF-κB Induction by Bisperoxovanadium Compounds Requires CD45, p36LAT, PKC, and IKK Activity and Exhibits Kinetics of Activation Comparable to Those of TCR …
  605. NF-κB Signal Transduction by IKK Complexes
  606. NF-κB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL
  607. NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
  608. NF‐κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK‐related kinase
  609. NF‐κB activation mechanism of 4‐hydroxyhexenal via NIK/IKK and p38 MAPK pathway
  610. NF‐κB activation through IKK‐i‐dependent I‐TRAF/TANK phosphorylation
  611. NFκB inhibition and more: A side-by-side comparison of the inhibitors of IKK and proteasome
  612. Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90
  613. NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
  614. NOffl~-IKK/AND
  615. Noise-induced oscillatory shuttling of NF-{kappa} B in a two compartment IKK-NF-{kappa} BI {kappa} B-A20 signaling model
  616. Notch-1 activates estrogen receptor alpha-dependent transcription via IKK alpha
  617. Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells
  618. Novel components of the IKK complex
  619. Novel cross-talk within the IKK family controls innate immunity
  620. Novel IKK inhibitors: β-carbolines
  621. Novel splicing mutation in the NEMO (IKK‐gamma) gene with severe immunodeficiency and heterogeneity of X‐chromosome inactivation
  622. Novel tight-binding inhibitory factor-κB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local …
  623. Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer
  624. O019 TLR4-mediated IKK and MAPK activation is regulated by differential post-translational modification of TAK1
  625. Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-κB pathway
  626. Osteopontin induces nuclear factor κB-mediated promatrix metalloproteinase-2 activation through IκBα/IKK signaling pathways, and curcumin (diferulolylmethane) …
  627. Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis
  628. Overexpression of the tumor suppressor IKK alpha prevents development of malignant carcinomas and metastases in skin
  629. OXIDANT-INDUCED PRIMING OF THE MACROPHAGE INVOLVES TYROSINE PHOSPHORYLATION OF IKK VIA A SRC KINASE PATHWAY: 164
  630. Oxidative stress transiently decreases the IKK complex (IKKα, β, and γ), an upstream component of NF-κB signaling, after transient focal cerebral ischemia in mice
  631. Oyster IKK‐like protein shares structural and functional properties with its mammalian homologues
  632. P132 The human dead-box helicase 3 couples IKK-epsilon to IRF3 activation
  633. p27 Kip1 Attenuates Endotoxin-Induced Cardiac Dysfunction Through Inhibition of the IKK-NF-kB Pathway
  634. p38 MAPK, IKK-2 and Oxidative Stress Regulate Histone 3 Serine 10 Phosphorylation in Blood Monocytes and Alveolar Macrophages.
  635. p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO
  636. P52. The IKK inhibitors celastrol and parthenolide inhibit breast cancer cell proliferation and migration in vitro and osteolytic bone metastasis in vivo
  637. p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
  638. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche
  639. p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation
  640. PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer
  641. Peptides Corresponding to the N and C Termini of IκB-α,-β, and-ε as Probes of the Two Catalytic Subunits of IκB Kinase, IKK-1 and IKK-2
  642. Periodontitis modulates insulin signaling, c-Jun N-terminal kinase activity, IKK activity, and insulin receptor substrate-1 ser 307 phosphorylation in muscle and …
  643. Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death
  644. Pharmacological inhibition and silencing of classical IKK-NF-κB pathway by siRNA sensitizes cancer cells to doxorubicin
  645. Phosphorylation of H3 serine 10 by IKK α governs cyclical production of ROS in estrogen-induced transcription and ensures DNA wholeness
  646. Phosphorylation of serine 68 in the IκB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-α-induced NF …
  647. Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation
  648. PHYSIOLOGICAL AND PATHOLOGICAL ACTIVATION OF IKK AND IKK-RELATED KINASES
  649. Piceatannol prevents lipopolysaccharide (LPS)‐induced nitric oxide (NO) production and nuclear factor (NF)‐κB activation by inhibiting IκB kinase (IKK)
  650. PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl …
  651. PKC-zeta associates and phosphorylates IKK-α/β in breast cancer cells
  652. PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1
  653. POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κ B pathway
  654. Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer
  655. Pregnancy weight gain limitation by a supervised nutritional program influences placental NF-κB/IKK complex expression and oxidative stress
  656. Preliminary study of inhibition of human Tenon’s capsule fibroblasts in vitro by RNA interference targeting IKK-beta
  657. Probing the effect of IKK on FOXO3: a regulatory mechanism of apoptosis and autophagy in chemoresistance
  658. Profilin–PTEN interaction suppresses NF-κB activation via inhibition of IKK phosphorylation
  659. Profiling expression of NF-κB signaling target genes in IKK-2 inhibitor treated pterygium and conjunctiva fibroblast cells
  660. Programming cellular gene expression by IKK mediated NF-κB activation
  661. Protection from experimental colitis by theaflavin‐3,3′‐digallate correlates with inhibition of IKK and NF‐κB activation
  662. Protective effect of Aplysin on IKK/NF-kB signaling pathway and related cytokines in rats exposed to ethanol
  663. Protective effect of Ginkgolids (A+ B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia
  664. Protective effects of organic acid component from Taraxacum mongolicum Hand.-Mazz. against LPS-induced inflammation: regulating the TLR4/IKK/NF-κB signal …
  665. Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation
  666. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt …
  667. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways
  668. PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IκB kinase β (IKK-β)
  669. QSAR studies on imidazothienopyrazines as IKK‐β inhibitors: from 2D to 3D
  670. R‐roscovitine sensitizes anaplastic thyroid carcinoma cells to TRAIL‐induced apoptosis via regulation of IKK/NF‐κB pathway
  671. Rac1 and PAK1 are upstream of IKK‐ε and TBK‐1 in the viral activation of interferon regulatory factor‐3
  672. RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex
  673. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
  674. Real-time imaging of differential ligand-induced IKK activation and impact on the IκBα: NF-κB negative feedback loop within living cells and mice
  675. Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
  676. Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
  677. Recursion formulae for IKK system with two hierarchies
  678. Refrigerants-in the focus of attention at the IKK. Kaeltemittel-Messethema Nummer eins
  679. Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling
  680. Regulation and function of IKK and IKK-related kinases
  681. Regulation of BH3-only proteins by IKK, downstream of beta-common receptor signalling
  682. Regulation of bone metastasis by the IKK [beta]/FoxO3a axis
  683. Regulation of cell death and autophagy by IKK and NF‐κB: critical mechanisms in immune function and cancer
  684. Regulation of expression of Bcl-3 proto-oncogene by IKK ϵ
  685. Regulation of I-kappa-B kinase (IKK) Pathway by CARMA 1• Bcl-10• MALT-1 (CBM) Complex Promotes SNARE Complex Formation and Secretion in Platelets
  686. Regulation of IKK
  687. Regulation of IL-8 expression by IKK and histone deacetylases in ovarian cancer
  688. Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ
  689. Regulation of IκB kinase (IKK) γ/NEMO function by IKKβ-mediated phosphorylation
  690. Regulation of Survival by IKK (epsilon) in Inflammatory Breast Cancer Involves EpCAM
  691. Regulation of tumor necrosis factor receptor-1 and the IKK-NF-κB pathway by LDL receptor–related protein explains the antiinflammatory activity of this receptor
  692. Relationship of Inhibitory Effects of Dichroa febrifuga and on the Activation of
  693. Requirement of Hsp90 activity for I κ B kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κ B activation
  694. Resistin up-regulates COX-2 expression via TAK1-IKK-NF-κB signaling pathway
  695. Retroviral oncoprotein Tax deregulates NF‐κB by activating Tak1 and mediating the physical association of Tak1–IKK
  696. RhoA regulation of NF-κB activation is mediated by Cox-2-dependent feedback inhibition of IKK in kidney epithelial cells
  697. Rituximab-Mediated Inhibition of the Constitutive NIK/IKK/IκB/NF-κB Signaling Pathway in Non-Hodgkin’s Lymphoma (NHL) B-Cell Lines: Role in Chemo-Sensitization …
  698. Role of cAMP and IKK-2-dependent signaling in the realization of growth potential of mesenchymal progenitor cells
  699. Role of cAMP-and IKK-2-Dependent Signaling Pathways in Functional Stimulation of Mesenchymal Progenitor Cells with Alkaloid Songorine.
  700. Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways
  701. Role of IKK and oscillatory NFκB kinetics in MMP‐9 gene expression and chemoresistance to 5‐fluorouracil in RKO colorectal cancer cells
  702. Role of IKK-alpha in the EGFR Signaling Regulation
  703. Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats
  704. Role of PI3K/AKT/IKK pathway in NFκB-and β-catenin-dependent transcription in colorectal cancer
  705. Role of the adaptor protein CIKS in the activation of the IKK complex
  706. Role of the COP9 Signalosome and IKK Complexes in Atherosclerosis
  707. Role of the IKK complex during liver regeneration
  708. Roles of Akt/PKB and IKK complex in constitutive induction of NF-κB in hepatocellular carcinomas of transforming growth factor α/c-myc transgenic mice
  709. Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-κB in breast cancer
  710. Roles of IKK-β, IRF1, and p65 in the activation of chemokine genes by interferon-γ
  711. Rosiglitazone inhibits hepatic insulin resistance induced by chronic pancreatitis and IKK-β/NF-κB expression in liver
  712. Rosmarinic acid as a downstream inhibitor of IKK‐β in TNF‐α‐induced upregulation of CCL11 and CCR3
  713. S 2-38: Activation and homeostatic control of IKK and NF-kB in oncogenesis and innate immunity
  714. Salicylate Inhibition of IKK [Beta](I [Kappa] B Kinase) Reverses Insulin Resistance in Zucker (fa/fa) Rats
  715. Saturated FFA Induced NF-κB Activation Is Independent of IKK/IκBα in Aortic Endothelial Cells
  716. Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide …
  717. Screening of specific SiRNA targeting IKKβ in human keloid fibroblasts and construction of IKK β-siRNA expression vector☆
  718. Segregation of NF-κ B activation through NEMO/IKK γ by Tax and TNF α: implications for stimulus-specific interruption of oncogenic signaling
  719. Selective degradation of the IκB kinase (IKK) by autophagy
  720. Selective Retinoids That Inhibit IKK as Chemotherapeutic Agents Against Estrogen-Independent Breast Cancer Cells
  721. Selenium Compounds Inhibit IB Kinase (IKK) and Nuclear Factor-B (NF-B) in Prostate Cancer Cells1
  722. Selenium Compounds Inhibit IκB Kinase (IKK) and Nuclear Factor-κB (NF-κB) in Prostate Cancer Cells 1 Supported by Department of Defense Prostate Cancer …
  723. Sensitivity analysis of a computational model of the IKK-NF-{kappa} BI {kappa} B {alpha}-A20 signal transduction network
  724. Sensitivity analysis of parameters controlling oscillatory signalling in the NF-κB pathway: the roles of IKK and IκBα
  725. Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation
  726. Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism
  727. Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway
  728. Signal Processing by the Control Cycle of the IKK Kinase in the NFκB Signaling Axis
  729. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal …
  730. Signaling by the Mpl receptor involves IKK and NF‐κB
  731. Signaling pathways leading to the activation of IKK and MAPK by thymosin α1
  732. Silencing of the cell cycle checkpoint gene 14‐3‐3σ in basal cell carcinomas correlates with reduced expression of IKK‐α
  733. Simultaneous inhibition of Rac1 and IKK pathways sensitizes lung cancer cells to TNFα-mediated apoptosis
  734. Small molecule inhibitors of IKK kinase activity
  735. Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases
  736. Stable reconstitution of IKK-deficient mouse embryonic fibroblasts
  737. Statins prevent NF-κB transactivation independently of the IKK-pathway in human endothelial cells
  738. StIKKing together: do multiple IKK pathways cooperate in the DNA-damage response?
  739. Stimulation of IKK-γ oligomerization by the human T-cell leukemia virus oncoprotein Tax
  740. Stimulus specificity of gene expression programs determined by temporal control of IKK activity
  741. Structure and dynamics of the kinase IKK-β–A key regulator of the NF-kappa B transcription factor
  742. Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site
  743. SUBSTITUTED THIOPHENECARBOXAMIDES AS IKK-BETA SERINE-, THREONINE-PROTEIN KINASE INHIBITORS.
  744. Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
  745. Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase …
  746. SUMOyla ted CPAP is required for IKK-med iated NF-jB activa tion and enhances HBx-induce d NF-jB signal ing in HCC
  747. SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC
  748. Suppression by IKK-2 Inhibitor of IL-1-Induced Collagen Degradation by Corneal Fibroblasts
  749. Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated …
  750. Suppression of NF-κ B and NF-κ B-regulated gene expression by sulforaphane and PEITC through I κ B α, IKK pathway in human prostate cancer PC-3 cells
  751. Suppression of NF-κB and NF-κB-regulated gene expression by apigenin through IκBα and IKK pathway in TRAMP mice
  752. Suppression of TNFα‐mediated NFκb activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells
  753. Suppressor of IKK epsilon (SIKE) acts as a bridge between innate immune signalling pathway and cytoskeletal rearrangements
  754. Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells
  755. Sustained activation of protein kinase C downregulates nuclear factor-κB signaling by dissociation of IKK-γ and Hsp90 complex in human colonic epithelial cells
  756. Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
  757. Synergistic benefit in inflammatory arthritis by targeting IKK∊ and IFNβ
  758. Synergy between rhBMP-2 and IKK-inhibitor PS-1145 delivered via a porous biodegradable polymer implant
  759. Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors
  760. Synthesis and structure–activity relationship of imidazo (1, 2-a) thieno (3, 2-e) pyrazines as IKK-β inhibitors
  761. Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: improvement of in vitro activity
  762. Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents
  763. Synthesis of C‐14 and C‐13, H‐2‐labeled IKK inhibitor: [14C] and [13C4,D3]‐N‐(6‐chloro‐7‐methoxy‐9H‐pyrido[3,4‐b]indol‐8‐yl)‐2‐methyl‐3 …
  764. Synthesis of C‐14‐labeled novel IKK inhibitor: 2‐[14C]‐N‐(6‐chloro‐9H‐pyrido [3,4‐b]indol‐8‐yl)‐3‐pyridinecarboxamide
  765. Synthesis of inhibitors of the IKK-complex for the treatment of prostate cancer
  766. Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i
  767. T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome
  768. TAK 1 adaptor proteins, TAB 2 and TAB 3, link the signalosome to B‐cell receptor‐induced IKK activation
  769. TAK-ling IKK activation:“Ub” the judge
  770. TAK1 is a ubiquitin-dependent kinase of MKK and IKK
  771. TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation
  772. TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation
  773. TAK1‐binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL‐1 signaling pathway
  774. Tamoxifen reduces infiltration of inflammatory cells, apoptosis and inhibits IKK/NF-kB pathway after spinal cord injury in rats
  775. Tanshinone IIA inhibits LPS-induced NF-κB activation in RAW 264.7 cells: Possible involvement of the NIK–IKK, ERK1/2, p38 and JNK pathways
  776. Targeting IKK and NF-κB for therapy
  777. Targeting IKK in Basal-Like Breast Tumors as a Therapeutic Approach
  778. Targeting IKK Inhibits Multiple Myeloma (MM) Cell Growth in the Bone Marrow Microenvironment.
  779. Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats
  780. Targeting transcription factor NFκB: comparative analysis of proteasome and IKK inhibitors
  781. Tautomycetin suppresses the TNFα/NF-κB pathway via inhibition of IKK activation
  782. Tectorigenin regulates adipogenic differentiation and adipocytokines secretion via PPAR γ and IKK/NF-κ B signaling
  783. Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
  784. Temporal encoding and homeostatic control in the IKK-kappaNF-kappaB signaling system
  785. Tendon Healing In Vitro: Activation of NIK, IKK α, IKK β, and NF-κB Genes in Signal Pathway and Proliferation of Tenocytes
  786. Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling
  787. Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
  788. TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
  789. TGF-β promotes cancer progression through the xIAP: TAB1: TAK1: IKK axis in mammary epithelial cells
  790. The adipocyte IKK/NFkappaB pathway: a therapeutic target for insulin resistance.
  791. The anti-death machinery in IKK/NF-κB signaling
  792. The anti-inflammatory role for IkappaB kinase (IKK) beta through inhibition of ‘classical’macrophage activation
  793. The beginning of the end: IκB kinase (IKK) and NF-κB activation
  794. The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation
  795. The catalytic subunits of IκB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers
  796. The discovery of 2-amino-3, 5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases
  797. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
  798. The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis
  799. The effect of smoking and smoking cessation on the phosphorylation of IKK-ß in type 2 diabetic rats
  800. The HSP 90 inhibitor NVP‐AUY 922‐AG inhibits the PI 3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells
  801. The IkB kinase complex (IKK) contains two kinase subunits, IKKa and IKKb, necessary for IkB phosphorylation and NF-kB activation
  802. The IKK complex & TNFR1 signaling to NF-κB
  803. The IKK complex contributes to the induction of autophagy
  804. The IKK complex contributes to the induction of autophagy
  805. The IKK Complex, a Central Regulator of NF-kB Activation
  806. The IKK complex, a central regulator of NF-κB activation
  807. The IKK complex: an integrator of all signals that activate NF-κB?
  808. The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors
  809. The IKK inhibitor BMS-345541 affects multiple mitotic cell cycle transitions
  810. The IKK inhibitor BMS345541 affects aurora kinase expression in human melanoma
  811. The IKK Inhibitor PS1145 Allows to Overcome Imatinib Resistance.
  812. The IKK kinases: operators of antiviral signaling
  813. The IKK NF-κB system: a treasure trove for drug development
  814. The IKK subunit of I B kinase (IKK) is essential for nuclear factor B activation and prevention of apoptosis
  815. The IKK-2/IκBα/NF-κB Pathway Plays a Key Role in the Regulation of CCR3 and eotaxin-1 in Fibroblasts A CRITICAL LINK TO DERMATITIS IN IκBα-DEFICIENT MICE
  816. The IKK-NF-κB pathway: a source for novel molecular drug targets in pain therapy?
  817. The IKK-related kinases: from innate immunity to oncogenesis
  818. The IKK‐neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase‐dependent activation‐induced cell death
  819. The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer
  820. The IKK/nf-κb pathway
  821. The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
  822. The IKK/NFkB & B-catenin pathway is critical for migration, invasion and metastasis in colorectal cancer
  823. The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
  824. The influence of the signal dynamics of activated form of IKK on NF‐κB and anti‐apoptotic gene expressions: A systems biology approach
  825. The information system on cancer mortality and district characteristics (IKK) of the TUeV Rheinland
  826. The interplay of IKK, NF‐κB and RIPK 1 signaling in the regulation of cell death, tissue homeostasis and inflammation
  827. The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
  828. The IκB Kinase (IKK) and the Control of Immunity, Inflammation and Cancer
  829. The IκB kinase (IKK) complex as a critical regulator of immune responses
  830. The IκB kinase (IKK) complex is tripartite and contains IKKγ but not IKAP as a regular component
  831. The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
  832. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
  833. The IкB Kinase (IKK) Complex
  834. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
  835. The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex
  836. The NF-κ B pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance
  837. The NF-κB-independent functions of IKK subunits in immunity and cancer
  838. The physical association of protein kinase Cθ with a lipid raft-associated inhibitor of κB factor kinase (IKK) complex plays a role in the activation of the NF-κB cascade …
  839. The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity
  840. The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
  841. The role of IKK in constitutive activation of NF-κB transcription factor in prostate carcinoma cells
  842. The Role of IKK in Interferon–Dependent Signaling
  843. The role of IKK-induced NF-kB1 p105 proteolysis in T lymphocytes
  844. The role of the IKK complex in viral infections
  845. The role of the IKK-2/NF-kB signaling in cigarette smoke-induced airway inflammation
  846. The role of the IKK/NF-kappa B signaling pathways in the extinction of auditory fear condition
  847. The role of the non-canonical IKK complex in glioblastoma multiforme
  848. THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS
  849. The roles of APC2 and IKK in the regulation of beta-catenin signaling.
  850. The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral …
  851. The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway
  852. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
  853. The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
  854. The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt–IKK–NF-κB–MMP-9 axis
  855. The use of IKK inhibitor as a lymphocyte depleting agent (47.4)
  856. The zinc transporter SLC39A8 is a negative feedback regulator of NF-κB through zinc-mediated inhibition of IKK
  857. The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
  858. Theileria-induced constitutive IKK activation is independent of functional Hsp90
  859. Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study
  860. Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study Animal
  861. THIENOPYRIDAZINES AS IKK INHIBITORS
  862. Thiophene carboxamides as inhibitors of the enzyme IKK-2
  863. THU0024 Anti-Inflammatory Inhibitors Targeting Jak and IKK Have An Anabolic Effect on Type II Collagen Turnover ex Vivo
  864. TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6
  865. Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-B Pathways
  866. TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
  867. TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
  868. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
  869. TNF-α modulation of intestinal tight junction permeability is mediated by NIK/IKK-α axis activation of the canonical NF-κB pathway
  870. TNF-α-induced loss of IKK-α in skeletal muscle: implications for skeletal muscle oxidative phenotype
  871. TNFR1 determines progression of chronic liver injury in the IKK γ/Nemo genetic model
  872. TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification
  873. TNFα induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways
  874. Tracking the road from inflammation to cancer: the critical role of IkappaB kinase (IKK)
  875. TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice
  876. TRAF2 plays a critical role in maintaining lymphocyte homeostasis by regulating the basal activities of IKK and caspase-8
  877. TRAF2 suppresses basal IKK activity in resting cells and TNFα can activate IKK in TRAF2 and TRAF5 double knockout cells
  878. TRAF5-mediated Tax ubiquitination modulates IKK phosphorylation but not binding to NEMO
  879. Transient activation of NF-κ B through a TAK1/IKK kinase pathway by TGF-β 1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor …
  880. Triggering the interferon antiviral response through an IKK-related pathway
  881. Triggering the Interferon Antiviral Response Through an IKK-Related Pathway
  882. TRIM22 can activate the noncanonical NF-κ B pathway by affecting IKK α
  883. Tumor necrosis factor α stimulates endothelin-1 synthesis in rat hepatic stellate cells in hepatic wound healing through a novel IKK/JNK pathway
  884. Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
  885. Tumor necrosis factor α-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK
  886. Tumor necrosis factor-α-induced IKK phosphorylation of NF-κB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
  887. Tunable signal processing through a kinase control cycle: the IKK signaling node
  888. Two coordinated mechanisms underlie TNFα-induced immediate and delayed IKK activation
  889. Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes
  890. Ubiquitin-mediated activation of TAK1 and IKK
  891. Ubiquitin, TAK1 and IKK: is there a connection?
  892. Ubiquitination in signaling to and activation of IKK
  893. Ubiquitination-Dependent Activation of IKK
  894. Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome
  895. Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB
  896. Upregulation of IKK α/IKK β by integrin-linked kinase is required for HER2/neu-induced NF-κ B antiapoptotic pathway
  897. Use of molecular imaging to quantify response to IKK‐2 inhibitor treatment in murine arthritis
  898. Using RNA interference in lung cancer cells to target the IKK-NF-κB pathway
  899. Using structural analysis to investigate the function of Suppressor of IKK-epsilon (SIKE)
  900. Vaccinia virus E3L protein inhibits type I IFN induction throughthe RLH pathway and associates with MDA-5 and IKK-ϵ
  901. Validation of the anti-inflammatory properties of small-molecule IκB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative …
  902. Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
  903. Water extract of Cynanchi atrati Radix regulates inflammation and apoptotic cell death through suppression of IKK-mediated NF-κB signaling
  904. Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex
  905. WNT5A regulates chondrocyte differentiation through differential use of the CaN/NFAT and IKK/NF-κB pathways
  906. α-Catulin, a Rho signalling component, can regulate NF-κB through binding to IKK-β, and confers resistance to apoptosis
  907. β-Adrenergic stimulation induces interleukin-18 expression via β2-AR, PI3K, Akt, IKK, and NF-κB
  908. β-Carboline alkaloid suppresses NF-κB transcriptional activity through inhibition of IKK signaling pathway
  909. 驚” ºndangered documents ana, the accrued Zkk kk 9 consultation, following air Use IKK kk effort is taken to respect copyright of the

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