AUTOPHAGY: 1,000 SCIENTIFIC STUDIES

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Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning “self-devouring”[1] and κύτος kýtos, meaning “hollow”[2]) is the natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components.[3] It allows the orderly degradation and recycling of cellular components.[4][5]

Three forms of autophagy are commonly described: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). In macroautophagy, expendable cytoplasmic constituents are targeted and isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome,[6][7] which, in time, fuses with an available lysosome, bringing its specialty process of waste management and disposal; and eventually the contents of the vesicle (now called an autolysosome) are degraded and recycled.

In disease, autophagy has been seen as an adaptive response to stress, promoting survival of the cell; but in other cases it appears to promote cell death and morbidity. In the extreme case of starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels.

The name “autophagy” was in existence and frequently used from the middle of the 19th century[8]. In its present usage, the term autophagy was coined by Belgian biochemist Christian de Duve in 1963 based on his discovery of the functions of lysosome.[3] The identification of autophagy-related genes in yeast in the 1990s allowed researchers to deduce the mechanisms of autophagy,[9][10][11][12][13] which eventually led to the award of the 2016 Nobel Prize in Physiology or Medicine to Japanese researcher Yoshinori Ohsumi.[14]

1000 Scientific Studies all about Autophagy:

  1. Autophagy in the pathogenesis of disease
  2. Autophagy fights disease through cellular self-digestion
  3. Autophagy: process and function
  4. Methods in Mammalian Autophagy Research
  5. Autophagy regulates lipid metabolism
  6. Autophagy and Metabolism
  7. Autophagy: Renovation of Cells and Tissues
  8. Autophagy as a Regulated Pathway of Cellular Degradation
  9. Autophagy in immunity and inflammation
  10. Autophagy and Aging
  11. Autophagy and the Integrated Stress Response
  12. mTOR regulation of Autophagy
  13. Regulation Mechanisms and Signaling Pathways of Autophagy
  14. Role of Autophagy in cancer
  15. Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
  16. Induction of Autophagy and inhibition of tumorigenesis by beclin 1
  17. Autophagy in Health and Disease: A Double-Edged Sword
  18. Methods for monitoring Autophagy
  19. AMPK and mTOR regulate Autophagy through direct phosphorylation of Ulk1
  20. LC3 and Autophagy
  21. The role of Autophagy during the early neonatal starvation period
  22. Death by design: apoptosis, necrosis and Autophagy
  23. Autophagy in cell death: an innocent convict?
  24. TFEB Links Autophagy to Lysosomal Biogenesis
  25. Development by Self-Digestion: Molecular Mechanisms and Biological Functions of Autophagy
  26. Autophagy: cellular and molecular mechanisms
  27. A protein conjugation system essential for Autophagy
  28. Self-eating and self-killing: crosstalk between Autophagy and apoptosis
  29. Autophagy: molecular machinery for self-eating
  30. Suppression of basal Autophagy in neural cells causes neurodegenerative disease in mice
  31. Autophagy in Human Health and Disease
  32. Loss of Autophagy in the central nervous system causes neurodegeneration in mice
  33. Parkin is recruited selectively to impaired mitochondria and promotes their Autophagy
  34. Potential therapeutic applications of Autophagy
  35. Apoptosis, Autophagy, and more
  36. Autophagy Suppresses Tumorigenesis through Elimination of p62
  37. Mammalian Autophagy: core molecular machinery and signaling regulation
  38. LC3 conjugation system in mammalian Autophagy
  39. Endoplasmic Reticulum Stress Triggers Autophagy
  40. Autophagy and cancer
  41. The Beclin 1 network regulates Autophagy and apoptosis
  42. Escape of Intracellular Shigella from Autophagy
  43. Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
  44. Autophagy in infection, inflammation and immunity
  45. Impairment of starvation-induced and constitutive Autophagy in Atg7-deficient mice
  46. A Role for Ubiquitin in Selective Autophagy
  47. Autophagy: dual roles in life and death?
  48. Isofation and charact~~zation of Autophagy-defective mutants of
    Saccharomyces cerevisiae
  49. Autophagy Defends Cells Against Invading Group A Streptococcus
  50. Autophagy as a cell death and tumor suppressor mechanism
  51. Regulation of Mammalian Autophagy in Physiology and Pathophysiology
  52. Autophagy: from phenomenology to molecular understanding in less than a decade
  53. FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
  54. A Unified Nomenclature forAutophagy-related genes
  55. Autophagy in mammalian development and differentiation
  56. Lysosomes and Autophagy in cell death control
  57. Regulation of Autophagy by cytoplasmic p53
  58. Autophagy: in sickness and in health
  59. Network organization of the human Autophagy system
  60. Fission and selective fusion govern mitochondrial segregation and elimination by Autophagy
  61. Autophagy: assays and artifacts
  62. Autophagy Is Activated for Cell Survival after Endoplasmic Reticulum Stress
  63. Autophagy, Immunity, and Microbial Adaptations
  64. A key role for Autophagy and the Autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
  65. Endogenous HMGB1 regulates Autophagy
  66. Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria
  67. Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
  68. Autophagy mediates the mitotic senescence transition
  69. The molecular machinery of Autophagy: unanswered questions
  70. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
  71. The role of Autophagy in neurodegenerative disease
  72. Autophagy gone awry in neurodegenerative diseases
  73. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 Autophagy gene
  74. Dynamics and diversity in Autophagy mechanisms: lessons from yeast
  75. Autophagy-Dependent Viral Recognition by Plasmacytoid Dendritic Cells
  76. Toll‐like receptors control Autophagy
  77. The AMPK signalling pathway coordinates cell growth, Autophagy and metabolism
  78. Autophagy
  79. The role of Autophagy in cancer development and response to therapy
  80. p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
  81. Pancreatic cancers require Autophagy for tumor growth
  82. Autophagy in the Eukaryotic Cell
  83. Calpain-mediated cleavage of Atg5 switches Autophagy to apoptosis
  84. α-Synuclein Is Degraded by Both Autophagy and the Proteasome
  85. Autophagy Is Required to Maintain Muscle Mass
  86. Self-consumption: the interplay of Autophagy and apoptosis
  87. Autophagy-deficient mice develop multiple liver tumors
  88. Induction of Autophagy by spermidine promotes longevity
  89. Crosstalk between apoptosis, necrosis and Autophagy
  90. ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
  91. Lithium induces Autophagy by inhibiting inositol monophosphatase
  92. The Role of Autophagy in Cancer: Therapeutic Implications
  93. Emerging regulation and functions of Autophagy
  94. Loss of the Autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
  95. Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
  96. Autophagy regulation by p53
  97. ROS, mitochondria and the regulation of Autophagy
  98. Autophagy, amyloidogenesis and Alzheimer disease
  99. Molecular dissection of Autophagy: two ubiquitin-like systems
  100. Deconvoluting the context-dependent role for Autophagy in cancer
  101. The Molecular Mechanism of Autophagy
  102. Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
  103. Oxidative Stress and Autophagy
  104. Beclin 1, an Autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
  105. Autophagy and human diseases
  106. Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice
  107. Autophagy in chronically ischemic myocardium
  108. Autophagy and Cell Death
  109. DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
  110. Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex
  111. JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
  112. p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
  113. Autophagy suppresses tumor progression by limiting chromosomal instability
  114. Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis
  115. Apoptosis and Autophagy in nigral neurons of patients with Parkinson’s disease
  116. The Double-Edged Sword of Autophagy Modulation in Cancer
  117. Autophagy genes in immunity
  118. Reactive oxygen species are essential for Autophagy and specifically regulate the activity of Atg4
  119. Regulation of Autophagy by ROS: physiology and pathology
  120. The regulation of Autophagy – unanswered questions
  121. Can Autophagy promote longevity?
  122. Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
  123. Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
  124. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
  125. Nix is a selective Autophagy receptor for mitochondrial clearance
  126. Protein Turnover Via Autophagy: Implications for Metabolism
  127. Regulation and role of Autophagy in mammalian cells
  128. p62/SQSTM1 forms protein aggregates degraded by Autophagy and has a protective effect on huntingtin-induced cell death
  129. Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
  130. Autophagy modulation as a potential therapeutic target for diverse diseases
  131. Defective Autophagy leads to cancer
  132. Ambra1 regulates Autophagy and development of the nervous system
  133. Metabolic Control of Autophagy
  134. Autophagy: a regulated bulk degradation process inside cells
  135. Toll-like receptor signalling in macrophages links the Autophagy pathway to phagocytosis
  136. The role for Autophagy in cancer
  137. Autophagy and signaling: their role in cell survival and cell death
  138. Activated Ras requires Autophagy to maintain oxidative metabolism and tumorigenesis
  139. Eating Oneself and Uninvited Guests: Autophagy-Related Pathways in Cellular Defense
  140. Ubiquitination and selective Autophagy
  141. Autophagy in the Cellular Energetic Balance
  142. The mitochondrial permeability transition initiates Autophagy in rat hepatocytes
  143. Selective Autophagy: ubiquitin-mediated recognition and beyond
  144. Unveiling the roles of Autophagy in innate and adaptive immunity
  145. Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
  146. The role of the Atg1/ULK1 complex in Autophagy regulation
  147. Role of Autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
  148. HDAC6 rescues neurodegeneration and provides an essential link between Autophagy and the UPS
  149. In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
  150. Autophagy: Many paths to the same end
  151. Mechanisms of chaperone-mediated Autophagy
  152. Autophagy in Cancer: Good, Bad, or Both?
  153. Autophagy-Mediated Tumor Promotion
  154. Autophagy and cytokines
  155. Autophagy as a target for anticancer therapy
  156. Autophagy in metazoans: cell survival in the land of plenty
  157. Cargo recognition and trafficking in selective Autophagy
  158. Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study
  159. Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy
  160. Autophagy in neurons: a review.
  161. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by Autophagy
  162. Age-related Decline in Chaperone-mediated Autophagy
  163. Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
  164. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and Autophagy
  165. Autophagy and Human Disease
  166. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
  167. Autophagy in liver diseases
  168. Autophagy and related mechanisms of lysosome-mediated protein degradation
  169. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates Autophagy in disease pathogenesis
  170. Inhibition of mTOR induces Autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
  171. Historical landmarks of Autophagy research
  172. An Overview of the Molecular Mechanism of Autophagy
  173. Autophagy in skeletal muscle
  174. Life and death partners: apoptosis, Autophagy and the cross-talk between them
  175. During Autophagy mitochondria elongate, are spared from degradation and sustain cell viability
  176. Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
  177. Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
  178. Autophagy in malignant transformation and cancer progression
  179. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.
  180. The dynamic nature of Autophagy in cancer
  181. Autophagy regulates adipose mass and differentiation in mice
  182. Innate and Adaptive Immunity through Autophagy
  183. The ubiquitin kinase PINK1 recruits Autophagy receptors to induce mitophagy
  184. Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
  185. Autophagy regulation by nutrient signaling
  186. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
  187. Autophagy basics
  188. Exercise-induced BCL2-regulated Autophagy is required for muscle glucose homeostasis
  189. A role for the NAD-dependent deacetylase Sirt1 in the regulation of Autophagy
  190. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on Autophagy genes
  191. Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body
  192. Hypoxia-induced Autophagy: cell death or cell survival?
  193. Autophagy and other vacuolar protein degradation mechanisms
  194. NOD2 stimulation induces Autophagy in dendritic cells influencing bacterial handling and antigen presentation
  195. Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
  196. Autophagy: Basic Principles and Relevance to Disease
  197. mTOR: a pharmacologic target for Autophagy regulation
  198. Autophagy and tumorigenesis
  199. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
  200. The role of Autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
  201. Activation of antibacterial Autophagy by NADPH oxidases
  202. Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
  203. Autophagy
  204. Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
  205. Cellular Autophagy: surrender, avoidance and subversion by microorganisms
  206. Autophagy and apoptosis dysfunction in neurodegenerative disorders
  207. Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
  208. Compromised Autophagy and neurodegenerative diseases
  209. Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
  210. Studies on the mechanisms of Autophagy: formation of the autophagic vacuole.
  211. Autophagy in Ischemic Heart Disease
  212. Dopamine-modified α-synuclein blocks chaperone-mediated Autophagy
  213. Cardiac Autophagy is a maladaptive response to hemodynamic stress
  214. Autophagy, organelles and ageing
  215. A Novel Response of Cancer Cells to Radiation Involves Autophagy and Formation of Acidic Vesicles
  216. The selective Autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
  217. Autophagy and aging: keeping that old broom working
  218. Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity
  219. Autophagy and cancer
  220. Autophagy Is Essential for Preimplantation Development of Mouse Embryos
  221. Superoxide is the major reactive oxygen species regulating Autophagy
  222. Mitochondrial DNA that escapes from Autophagy causes inflammation and heart failure
  223. Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
  224. Bif-1 interacts with Beclin 1 through UVRAG and regulates Autophagy and tumorigenesis
  225. ULK1 induces Autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
  226. Autophagy Links Inflammasomes to Atherosclerotic Progression
  227. Sequence variants in the Autophagy gene IRGM and multiple other replicating loci contribute to Crohn’s disease susceptibility
  228. Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
  229. Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
  230. The apoptosis/Autophagy paradox: autophagic vacuolization before apoptotic death
  231. Autophagy maintains stemness by preventing senescence
  232. Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy
  233. Chaperone-mediated Autophagy: roles in disease and aging
  234. Autophagy inhibition in combination cancer treatment.
  235. Novel targets for Huntington’s disease in an mTOR-independent Autophagy pathway
  236. Senescence, Apoptosis or Autophagy?
  237. Programmed cell death pathways in cancer: a review of apoptosis, Autophagy and programmed necrosis
  238. Enhancing Immunity Through Autophagy
  239. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate Autophagy at different stages
  240. Activation of Chaperone-mediated Autophagy during Oxidative Stress
  241. Connecting endoplasmic reticulum stress to Autophagy by unfolded protein response and calcium
  242. Response to myocardial ischemia/reperfusion injury involves Bnip3 and Autophagy
  243. Identification of a candidate therapeutic Autophagy-inducing peptide
  244. Autophagy in infection
  245. A block of Autophagy in lysosomal storage disorders
  246. HDAC6 controls autophagosome maturation essential for ubiquitin‐selective quality‐control Autophagy
  247. Autophagy: for better or for worse
  248. Regulation of starvation- and virus-induced Autophagy by the eIF2α kinase signaling pathway
  249. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
  250. ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, Autophagy and senescence
  251. Targeting Autophagy in cancer
  252. Secretory Autophagy
  253. Cytoprotective roles for Autophagy
  254. Nod1 and Nod2 direct Autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
  255. Small molecules enhance Autophagy and reduce toxicity in Huntington’s disease models
  256. Autophagy at the crossroads of catabolism and anabolism
  257. The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes
  258. The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy
  259. Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer’s Disease
  260. Autophagy and oxidative stress associated with gold nanoparticles
  261. The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
  262. The Association of AMPK with ULK1 Regulates Autophagy
  263. Autophagy: a barrier or an adaptive response to cancer
  264. Phosphorylation of Ribosomal Protein S6 Is Inhibitory for Autophagy in Isolated Rat Hepatocytes
  265. The role of Autophagy in the heart
  266. Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
  267. An Overview of Autophagy: Morphology, Mechanism, and Regulation
  268. The Beclin 1–VPS34 complex – at the crossroads of Autophagy and beyond
  269. Consequences of the selective blockage of chaperone-mediated Autophagy
  270. The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon
  271. Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation
  272. Role and regulation of Autophagy in cancer
  273. Control of Autophagy by oncogenes and tumor suppressor genes
  274. HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein
  275. Dengue Virus-Induced Autophagy Regulates Lipid Metabolism
  276. Anti- and pro-tumor functions of Autophagy
  277. Chaperone‐Mediated Autophagy in Aging and Disease
  278. Chaperone-mediated Autophagy: a unique way to enter the lysosome world
  279. The pleiotropic role of Autophagy: from protein metabolism to bactericide
  280. Autophagy delays apoptotic death in breast cancer cells following DNA damage
  281. Autophagy in neurodegenerative disease: friend, foe or turncoat?
  282. Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy
  283. Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting inSaccharomyces cerevisiae
  284. Autophagosome Formation and Molecular Mechanism of Autophagy
  285. p53: The Janus of Autophagy?
  286. The LIR motif – crucial for selective Autophagy
  287. E2F1 regulates Autophagy and the transcription of Autophagy genes
  288. Cargo recognition failure is responsible for inefficient Autophagy in Huntington’s disease
  289. Viruses and Autophagy
  290. Non-selective Autophagy.
  291. Autophagy in the liver
  292. Autophagy and neurodegeneration: when the cleaning crew goes on strike
  293. Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β
  294. NF-κB Activation Represses Tumor Necrosis Factor-α-induced Autophagy
  295. Oxidative stress and Autophagy: the clash between damage and metabolic needs
  296. Interplay of LRRK2 with chaperone-mediated Autophagy
  297. Physiological Functions of Autophagy
  298. Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
  299. Studies on the mechanisms of Autophagy: maturation of the autophagic vacuole.
  300. Selective Mitochondrial Autophagy, or Mitophagy, as a Targeted Defense Against Oxidative Stress, Mitochondrial Dysfunction, and Aging
  301. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
  302. Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
  303. Autophagy: Principles and significance in health and disease
  304. Autophagy failure in Alzheimer’s disease—locating the primary defect
  305. Lipophagy: Connecting Autophagy and Lipid Metabolism
  306. Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
  307. The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment
  308. Autophagy and apoptosis: what is the connection?
  309. Autophagy as a therapeutic target in cancer
  310. Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
  311. FoxO Transcription Factors Promote Autophagy in Cardiomyocytes
  312. Autophagy: A lysosomal degradation pathway with a central role in health and disease
  313. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
  314. Cerebral Ischemia-Hypoxia Induces Intravascular Coagulation and Autophagy
  315. Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains
  316. Autophagy and the Immune System
  317. FLIP-mediated Autophagy regulation in cell death control
  318. Autophagy and multivesicular bodies: two closely related partners
  319. The TBK1 adaptor and Autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
  320. Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
  321. Activation of Autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
  322. Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
  323. Galectin 8 targets damaged vesicles for Autophagy to defend cells against bacterial invasion
  324. Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
  325. Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival
  326. Autophagy in innate and adaptive immunity
  327. Physiological functions of Atg6/Beclin 1: a unique Autophagy-related protein
  328. Autophagy in Idiopathic Pulmonary Fibrosis
  329. ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for Autophagy formation
  330. Autophagy as an immune defense mechanism
  331. Inflammaging: disturbed interplay between Autophagy and inflammasomes
  332. Apoptosis, Autophagy, necroptosis, and cancer metastasis
  333. Neutrophil extracellular trap cell death requires both Autophagy and superoxide generation
  334. Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
  335. Physiological significance of selective degradation of p62 by Autophagy
  336. Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
  337. Autophagy and Cellular Immune Responses
  338. Role of BNIP3 and NIX in cell death, Autophagy, and mitophagy
  339. The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
  340. Cell death by Autophagy: facts and apparent artefacts
  341. PAMPs and DAMPs: signal 0s that spur Autophagy and immunity
  342. Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy
  343. Lysosomal calcium signalling regulates Autophagy through calcineurin and TFEB
  344. Chaperone-mediated Autophagy in protein quality control
  345. Novel System for Monitoring Autophagy in the Yeast Saccharomyces cerevisiae
  346. Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
  347. Autophagy and apoptosis: where do they meet?
  348. Plant Autophagy—more than a starvation response
  349. Regulation of Autophagy by the inositol trisphosphate receptor
  350. Selective degradation of p62 by Autophagy
  351. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and Autophagy
  352. MicroRNA regulation of Autophagy
  353. Autophagy and Autophagy-related proteins in the immune system
  354. Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
  355. Autophagy and neurodegeneration
  356. Apoptosis and Autophagy: regulatory connections between two supposedly different processes
  357. A critical role for the Autophagy gene Atg5 in T cell survival and proliferation
  358. Control of Autophagy as a therapy for neurodegenerative disease
  359. Atg8: an Autophagy-related ubiquitin-like protein family
  360. Autophagy Controls Salmonella Infection in Response to Damage to the Salmonella-containing Vacuole
  361. Autophagy and metastasis: another double-edged sword
  362. Mitochondrial fusion, fission and Autophagy as a quality control axis: The bioenergetic view
  363. Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission
  364. Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy
  365. Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death
  366. Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy
  367. Bacteria–Autophagy interplay: a battle for survival
  368. Autophagy in human type 2 diabetes pancreatic beta cells
  369. Autophagy, Metabolism, and Cancer
  370. Molecular definitions of Autophagy and related processes
  371. Autophagy genes and ageing
  372. Autophagy–physiology and pathophysiology
  373. Protective role of Autophagy in neonatal hypoxia–ischemia induced brain injury
  374. Neuronal Autophagy and neurodegenerative diseases
  375. Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
  376. Autophagy in Antimicrobial Immunity
  377. Induction of Autophagy in Axonal Dystrophy and Degeneration
  378. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
  379. The role of Autophagy-lysosome pathway in neurodegeneration associated with Parkinson’s disease
  380. Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy
  381. The Autophagy effector Beclin 1: a novel BH3-only protein
  382. The Autophagy machinery is required to initiate hepatitis C virus replication
  383. Autophagy in tumour suppression and promotion
  384. Bcl-2 Inhibition of Autophagy: A New Route to Cancer?
  385. ESCRTs and Fab1 Regulate Distinct Steps of Autophagy
  386. FOXO3A directs a protective Autophagy program in haematopoietic stem cells
  387. Atg8‐family interacting motif crucial for selective Autophagy
  388. p53 status determines the role of Autophagy in pancreatic tumour development
  389. DNA damage and Autophagy
  390. Chaperone-mediated Autophagy: selectivity pays off
  391. Autophagy
  392. Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice
  393. microRNA‐101 is a potent inhibitor of Autophagy
  394. Nutrient-sensing nuclear receptors coordinate Autophagy
  395. A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
  396. Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury
  397. Cytoplasmic bacteria can be targets for Autophagy
  398. The multiple roles of Autophagy in cancer
  399. Autophagy is a therapeutic target in anticancer drug resistance
  400. Regulation of the aging process by Autophagy
  401. Autophagy and cell death in model organisms
  402. The Autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
  403. Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes
  404. Image-based genome-wide siRNA screen identifies selective Autophagy factors
  405. Autophagy and Cancer Therapy
  406. PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy
  407. Absence of Autophagy results in reactive oxygen species-dependent amplification of RLR signaling
  408. Autophagy and human disease: emerging themes
  409. Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment
  410. Chemical modulators of Autophagy as biological probes and potential therapeutics
  411. Pathophysiology of chaperone-mediated Autophagy
  412. Regulation of endoplasmic reticulum turnover by selective Autophagy
  413. Autosis and autophagic cell death: the dark side of Autophagy
  414. The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
  415. Regulation of the Autophagy protein LC3 by phosphorylation
  416. Therapeutic targets in cancer cell metabolism and Autophagy
  417. Autophagy: Pathways for Self-Eating in Plant Cells
  418. An Autophagy–Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis
  419. Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase
  420. Mechanisms of Selective Autophagy
  421. Mechanisms of cross‐talk between the ubiquitin‐proteasome and Autophagy‐lysosome systems
  422. Chaperone-Mediated Autophagy
  423. A novel assay to study Autophagy: regulation of autophagosome vacuole size by amino acid deprivation
  424. Coordination of membrane events during Autophagy by multiple class III PI3-kinase complexes
  425. Molecular mechanism and regulation of Autophagy
  426. Induction of Autophagy by amino-acid deprivation in perfused rat liver
  427. Modulation of intracellular ROS levels by TIGAR controls Autophagy
  428. Mechanisms of Autophagy
  429. Cross talk between apoptosis and Autophagy by caspase-mediated cleavage of Beclin 1
  430. Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
  431. Degradation of Oxidized Proteins by Autophagy during Oxidative Stress in Arabidopsis
  432. The Autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
  433. Autophagy in immunity and cell‐autonomous defense against intracellular microbes
  434. The Reversible Modification Regulates the Membrane-Binding State of Apg8/Aut7 Essential for Autophagy and the Cytoplasm to Vacuole Targeting Pathway
  435. Overexpression of Atg5 in mice activates Autophagy and extends lifespan
  436. TAK1 activates AMPK‐dependent cytoprotective Autophagy in TRAIL‐treated epithelial cells
  437. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
  438. Integration of Clearance Mechanisms: The Proteasome and Autophagy
  439. Role of Autophagy in suppression of inflammation and cancer
  440. Autophagy is an immediate macrophage response to Legionella pneumophila
  441. Stimulation of Autophagy by the p53 target gene Sestrin2
  442. Functional interaction between Autophagy and ciliogenesis
  443. Role of mitochondrial permeability transition pores in mitochondrial Autophagy
  444. Autophagy: An Emerging Immunological Paradigm
  445. MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages
  446. The eIF2α/ATF4 pathway is essential for stress-induced Autophagy gene expression
  447. Ubiquitin-Dependent And Independent Signals In Selective Autophagy
  448. UPR, Autophagy, and mitochondria crosstalk underlies the ER stress response
  449. Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
  450. Autophagy in Huntington disease and huntingtin in Autophagy
  451. Selective Autophagy in Cancer Development and Therapy
  452. Signalling and Autophagy regulation in health, aging and disease
  453. Autophagy in nonalcoholic steatohepatitis
  454. Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing Autophagy
  455. Extracellular matrix regulation of Autophagy
  456. HMGB1 release and redox regulates Autophagy and apoptosis in cancer cells
  457. Autophagy in the cardiovascular system
  458. Crosstalk Between Autophagy and Apoptosis in Heart Disease
  459. The anticancer drug imatinib induces cellular Autophagy
  460. Complex Inhibitory Effects of Nitric Oxide on Autophagy
  461. Initiation of apoptosis and Autophagy by photodynamic therapy
  462. Autophagy mediates degradation of nuclear lamina
  463. Role of LAMP-2 in Lysosome Biogenesis and Autophagy
  464. NBR1 and p62 as cargo receptors for selective Autophagy of ubiquitinated targets
  465. Mature ribosomes are selectively degraded upon starvation by an Autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
  466. Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability
  467. Autophagy and cancer cell metabolism
  468. TFEB-mediated Autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
  469. Crosstalk between apoptosis and Autophagy within the Beclin 1 interactome
  470. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
  471. Activation of Autophagy protects against acetaminophen‐induced hepatotoxicity
  472. Enhanced Autophagy ameliorates cardiac proteinopathy
  473. Following Autophagy step by step
  474. Akt inhibition promotes Autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
  475. Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection
  476. Restoration of chaperone-mediated Autophagy in aging liver improves cellular maintenance and hepatic function
  477. Autophagy in cardiovascular disease
  478. Canonical and non-canonical Autophagy: variations on a common theme of self-eating?
  479. Approaching the Molecular Mechanism of Autophagy
  480. Does Autophagy have a license to kill mammalian cells?
  481. Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
  482. Generation of cell lines with tetracycline‐regulated Autophagy and a role for Autophagy in controlling cell size
  483. Chaperone-mediated Autophagy at a glance
  484. Efficient Cross-presentation Depends on Autophagy in Tumor Cells
  485. Autophagy: Regulation and role in disease
  486. Atg17 Functions in Cooperation with Atg1 and Atg13 in Yeast Autophagy
  487. Autophagy in cardiac myocyte homeostasis, aging, and pathology
  488. Autophagy, Cytoplasm-to-Vacuole Targeting Pathway, and Pexophagy in Yeast and Mammalian Cells
  489. Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution
  490. A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
  491. TBK-1 Promotes Autophagy–Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
  492. Role of Autophagy in G2019S‐LRRK2‐associated neurite shortening in differentiated SH‐SY5Y cells
  493. Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
  494. Ammonia-induced Autophagy is independent of ULK1/ULK2 kinases
  495. Autophagy, a guardian against neurodegeneration
  496. Autophagy Contributes to Caspase-independent Macrophage Cell Death
  497. Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
  498. Autophagy in cardiovascular biology
  499. Autophagy: machinery and regulation
  500. Mammalian Autophagy: How Does It Work?
  501. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
  502. Autophagy in proximal tubules protects against acute kidney injury
  503. Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
  504. Aggresomes and Autophagy Generate Sites for Virus Replication
  505. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
  506. Autophagy and adaptive immunity
  507. Synergistic Augmentation of Rapamycin-Induced Autophagy in Malignant Glioma Cells by Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibitors
  508. Postischemic treatment of neonatal cerebral ischemia should target Autophagy
  509. Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
  510. p65/RelA Modulates BECN1 Transcription and Autophagy
  511. Autophagy in health and disease. 1. Regulation and significance of Autophagy: an overview
  512. Plasma cells require Autophagy for sustainable immunoglobulin production
  513. Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3
  514. Glucocorticoid‐induced Autophagy in osteocytes
  515. An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
  516. Eating the endoplasmic reticulum: quality control by Autophagy
  517. Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
  518. siRNA Screening of the Kinome Identifies ULK1 as a Multidomain Modulator of Autophagy
  519. Autophagy and Tumorigenesis
  520. Chaperone-mediated Autophagy: Molecular mechanisms and physiological relevance
  521. Cytosolic FoxO1 is essential for the induction of Autophagy and tumour suppressor activity
  522. Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
  523. Autophagy activation by rapamycin reduces severity of experimental osteoarthritis
  524. A New Protein Conjugation System in Human
    THE COUNTERPART OF THE YEAST Apg12p CONJUGATION SYSTEM ESSENTIAL FOR Autophagy
  525. Role of Mitochondrial Inner Membrane Permeabilization in Necrotic Cell Death, Apoptosis, and Autophagy
  526. Mutant p53 protein localized in the cytoplasm inhibits Autophagy
  527. SIRT1: Regulation of longevity via Autophagy
  528. Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila
  529. Regulation of Autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of Autophagy enhancers
  530. Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
  531. Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
  532. Control of Autophagy initiation by phosphoinositide 3‐phosphatase jumpy
  533. Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos
  534. How to Live Long and Prosper: Autophagy, Mitochondria, and Aging
  535. Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus
  536. Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic Autophagy deficiency
  537. Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
  538. Rapamycin protects against rotenone-induced apoptosis through Autophagy induction
  539. Proteases in Autophagy
  540. Adipose-specific deletion of Autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
  541. The Four Faces of Autophagy: Implications for Cancer Therapy
  542. Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by Autophagy
  543. Autophagy Signaling Through Reactive Oxygen Species
  544. PARTICIPATION OF LYSOSOMES IN CELLULAR Autophagy INDUCED IN RAT LIVER BY GLUCAGON
  545. Autophagy for tissue homeostasis and neuroprotection
  546. Molecules and their functions in Autophagy
  547. Aβ Secretion and Plaque Formation Depend on Autophagy
  548. Structural basis of target recognition by Atg8/LC3 during selective Autophagy
  549. Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
  550. Metformin inhibits melanoma development through Autophagy and apoptosis mechanisms
  551. Altered Autophagy in Human Adipose Tissues in Obesity
  552. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
  553. Aggregate‐Prone Proteins Are Cleared from the Cytosol by Autophagy: Therapeutic Implications
  554. MicroRNAs in apoptosis, Autophagy and necroptosis
  555. Relationship between the proteasomal system and Autophagy
  556. Rapamycin and mTOR-independent Autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
  557. Autophagy Induction by the Pathogen Receptor CD46
  558. PUMA- and Bax-induced Autophagy contributes to apoptosis
  559. Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption
  560. mTORC1 Phosphorylates the ULK1-mAtg13-FIP200 Autophagy Regulatory Complex
  561. Eating the enemy within: Autophagy in infectious diseases
  562. INFLUENCE OF GLUCAGON, AN INDUCER OF CELLULAR Autophagy, ON SOME PHYSICAL PROPERTIES OF RAT LIVER LYSOSOMES
  563. Downregulated MEG3 activates Autophagy and increases cell proliferation in bladder cancer
  564. Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
  565. Regulation of Autophagy by the p300 Acetyltransferase
  566. GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation
  567. Keap1 degradation by Autophagy for the maintenance of redox homeostasis
  568. Viruses and the Autophagy machinery
  569. Autophagy: molecular mechanisms, physiological functions and relevance in human pathology
  570. Essential role for Autophagy in life span extension
  571. Targeting Autophagy Addiction in Cancer
  572. p62, an Autophagy hero or culprit?
  573. Autophagy in Yeast: ATOR-Mediated Response to Nutrient Starvation
  574. The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation
  575. BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy
  576. The unfolded protein response protects human tumor cells during hypoxia through regulation of the Autophagy genes MAP1LC3B and ATG5
  577. p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
  578. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian Autophagy
  579. Valosin-containing protein (VCP) is required for Autophagy and is disrupted in VCP disease
  580. Autophagy in Load-Induced Heart Disease
  581. To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
  582. Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and MacroAutophagy in Neuronal Cells
  583. Protein breakdown in muscle wasting: Role of Autophagy-lysosome and ubiquitin-proteasome
  584. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
  585. How do ESCRT proteins control Autophagy?
  586. Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson’s Disease
  587. Autophagy: a multifaceted intracellular system for bulk and selective recycling
  588. Autophagy promotes synapse development in Drosophila
  589. Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
  590. Spermidine and resveratrol induce Autophagy by distinct pathways converging on the acetylproteome
  591. Noncanonical Autophagy Promotes the Visual Cycle
  592. Regulation of Autophagy by ATF4 in response to severe hypoxia
  593. C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms
  594. Chapter 10 Monitoring Autophagy by Electron Microscopy in Mammalian Cells
  595. Glycogen Autophagy in glucose homeostasis
  596. mTOR inhibits Autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
  597. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte Autophagy
  598. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing Autophagy
  599. Autophagy in cellular growth control
  600. Suppression of Autophagy by FIP200 deletion inhibits mammary tumorigenesis
  601. AMPK and Autophagy get connected
  602. Processing of ATG8s, Ubiquitin-Like Proteins, and Their Deconjugation by ATG4s Are Essential for Plant Autophagy
  603. Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
  604. Transcriptional control of Autophagy–lysosome function drives pancreatic cancer metabolism
  605. Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn’s Disease Associated ATG16L1 Variant
  606. Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and Autophagy as a host defence mechanism
  607. The return of the nucleus: transcriptional and epigenetic control of Autophagy
  608. Autophagy and disease: always two sides to a problem
  609. Early endosomes and endosomal coatomer are required for Autophagy
  610. A role for Autophagy during hepatic stellate cell activation
  611. Autophagy in Yeast: Mechanistic Insights and Physiological Function
  612. Apg16p is required for the function of the Apg12p–Apg5p conjugate in the yeast Autophagy pathway
  613. Nonselective Autophagy of cytosolic enzymes by isolated rat hepatocytes.
  614. Autophagy Is Required for Maintenance of Amino Acid Levels and Protein Synthesis under Nitrogen Starvation
  615. Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
  616. Identification of Barkor as a mammalian Autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
  617. HDACs link the DNA damage response, processing of double-strand breaks and Autophagy
  618. Autophagy and Cancer
  619. Autophagy—a key player in cellular and body metabolism
  620. Sirtuins’ modulation of Autophagy
  621. Tumor Vessel Normalization by Chloroquine Independent of Autophagy
  622. Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
  623. Autophagy in neurodegeneration and development
  624. The Cvt pathway as a model for selective Autophagy
  625. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
  626. Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
  627. Regulation of Autophagy by Extracellular Signal-Regulated Protein Kinases During 1-Methyl-4-Phenylpyridinium-Induced Cell Death
  628. Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
  629. Autophagy: links with the proteasome
  630. The crosstalk between Autophagy and apoptosis: where does this lead?
  631. Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
  632. The tumor suppressor gene ARHI regulates Autophagy and tumor dormancy in human ovarian cancer cells
  633. Autophagy and Tumor Metabolism
  634. Essential role for Autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
  635. Autophagy in Protein and Organelle Turnover
  636. Sphingolipids: regulators of crosstalk between apoptosis and Autophagy
  637. HMGB1-induced Autophagy promotes chemotherapy resistance in leukemia cells
  638. Regulation of Autophagy by phosphatidylinositol 3-phosphate
  639. Focal cerebral ischemia induces upregulation of Beclin 1 and Autophagy–like cell death
  640. Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
  641. Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma
  642. Autophagy in filamentous fungi
  643. Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy
  644. Regulation of innate immune responses by Autophagy-related proteins
  645. Participation of Autophagy in renal ischemia/reperfusion injury
  646. Ubiquilin functions in Autophagy and is degraded by chaperone-mediated Autophagy
  647. Structural Aspects of Autophagy
  648. Chapter 1 Monitoring Autophagy in Mammalian Cultured Cells through the Dynamics of LC3
  649. Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy
  650. Autophagy proteins regulate ERK phosphorylation
  651. Autophagy in cancer metastasis
  652. GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
  653. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
  654. Targeting Autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells
  655. Function and Molecular Mechanism of Acetylation in Autophagy Regulation
  656. Digesting the Expanding Mechanisms of Autophagy
  657. Autophagy—A double‐edged sword in oncology
  658. The dual role of Autophagy in cancer
  659. Emerging Role for Autophagy in the Removal of Aggresomes in Schwann Cells
  660. A Salmonella protein causes macrophage cell death by inducing Autophagy
  661. Recycle or die: The role of Autophagy in cardioprotection
  662. Autophagy in Atherosclerosis
  663. Autophagy is an adaptive response in desmin-related cardiomyopathy
  664. Autophagy in Diabetic Nephropathy
  665. Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by Autophagy
  666. Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient Deprivation
  667. Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens
  668. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
  669. Autophagy in Vascular Disease
  670. Targeting Autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
  671. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial Autophagy in mouse aged kidney
  672. Autophagy contributes to resistance of tumor cells to ionizing radiation
  673. EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
  674. Development of Autophagy inducers in clinical medicine
  675. Role of Autophagy in Cancer Prevention
  676. Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis
  677. Peroxisome turnover by micropexophagy: an Autophagy-related process
  678. In Situ Detection of Starvation-induced Autophagy
  679. Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
  680. Bcl-2:Beclin 1 complex: multiple, mechanisms regulating Autophagy/apoptosis toggle switch
  681. Receptor-mediated selective Autophagy degrades the endoplasmic reticulum and the nucleus
  682. Diet, Autophagy, and Cancer: A Review
  683. A dual role for Ca2+ in Autophagy regulation
  684. Autophagy and antiviral immunity
  685. p62/SQSTM1 functions as a signaling hub and an Autophagy adaptor
  686. Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
  687. Protein and mRNA expression of Autophagy gene Beclin 1 in human brain tumours
  688. Methods for Assessing Autophagy and Autophagic Cell Death
  689. Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired MacroAutophagy
  690. Regulation of lipid droplets by Autophagy
  691. Autophagy in cardiac myocytes.
  692. Membrane Recruitment of Aut7p in the Autophagy and Cytoplasm to Vacuole Targeting Pathways Requires Aut1p, Aut2p, and the Autophagy Conjugation Complex
  693. Increased Autophagy in transgenic mice with a G93A mutant SOD1 gene
  694. p38 and JNK MAPK pathways control the balance of apoptosis and Autophagy in response to chemotherapeutic agents
  695. Huntington’s disease: degradation of mutant huntingtin by Autophagy
  696. Autophagy modulation for cancer therapy
  697. Atg5: more than an Autophagy factor
  698. Apoptosis and Autophagy: Targeting Autophagy signallingin cancer cells – ‘trick or treats’?
  699. DAP‐kinase‐mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl‐XL and induction of Autophagy
  700. Negative regulation of Autophagy
  701. Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
  702. Journal of the American College of Cardiology
  703. Autophagy regulates TNFα-mediated joint destruction in experimental arthritis
  704. Cholesterol depletion induces Autophagy
  705. Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
  706. Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles
  707. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via Autophagy enhancement
  708. Genetic and Phenotypic Overlap between Autophagy and the Cytoplasm to Vacuole Protein Targeting Pathway
  709. JNK regulates FoxO-dependent Autophagy in neurons
  710. Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
  711. DNA damaging agent-induced Autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
  712. Autophagy, plant senescence, and nutrient recycling
  713. Guidelines for the use and interpretation of assays for monitoring Autophagy
  714. p62 links Autophagy and Nrf2 signaling
  715. Non‐autophagic roles of Autophagy‐related proteins
  716. Autophagy in atherosclerosis
  717. Autophagy and pancreatitis
  718. Radiation-induced Autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
  719. Dual roles of Autophagy in the survival of Caenorhabditis elegans during starvation
  720. Transcriptional regulation of Autophagy by an FXR–CREB axis
  721. Autophagy and neurodegeneration
  722. Autophagy Plays a Role in Chloroplast Degradation during Senescence in Individually Darkened Leaves
  723. Structure of Atg5·Atg16, a Complex Essential for Autophagy
  724. Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
  725. mTOR and Autophagy: A dynamic relationship governed by nutrients and energy
  726. TOR-dependent control of Autophagy: biting the hand that feeds
  727. Starving Neurons Show Sex Difference in Autophagy
  728. Targeting ER stress–induced Autophagy overcomes BRAF inhibitor resistance in melanoma
  729. Starvation‐induced expression of Autophagy‐related genes in Arabidopsis
  730. Involvement of Autophagy in trypsinogen activation within the pancreatic acinar cells
  731. ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
  732. The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
  733. BAG3 mediates chaperone‐based aggresome‐targeting and selective Autophagy of misfolded proteins
  734. The Role of Lipids in the Control of Autophagy
  735. mTOR’s role in ageing: protein synthesis or Autophagy?
  736. Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy
  737. Selective types of Autophagy in yeast
  738. The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes Autophagy
  739. Regulation of Autophagy by the Rab GTPase network
  740. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
  741. Bcl‐2 and Bcl‐xL play important roles in the crosstalk between Autophagy and apoptosis
  742. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
  743. Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues
  744. Inhibition of Autophagy in Mitotic Animal Cells
  745. Crohn’s disease: NOD2, Autophagy and ER stress converge
  746. Autophagy and inflammatory diseases
  747. Autophagy
  748. Regulation of Autophagy by stress-responsive transcription factors
  749. Dengue Virus and Autophagy
  750. Analyses of APG13 gene involved in Autophagy in yeast, Saccharomyces cerevisiae
  751. The Impact of Autophagy on Cell Death Modalities
  752. Regulation of Autophagy in mammals and its interplay with apoptosis
  753. Aging: Central role for Autophagy and the lysosomal degradative system
  754. Autophagy and the degradation of mitochondria
  755. Dependence of hepatocytic Autophagy on intracellularly sequestered calcium.
  756. Autophagy in Innate Immunity against Intracellular Bacteria
  757. Autophagy: Role in surviving environmental stress
  758. Autophagy: Is It Cancer’s Friend or Foe?
  759. Autophagy and Its Role in MHC-Mediated Antigen Presentation
  760. Autophagy and genomic integrity
  761. Autophagy induction favours the generation and maturation of the Coxiella‐replicative vacuoles
  762. Autophagy and p62 in Cardiac Proteinopathy
  763. Ordered Organelle Degradation during Starvation-induced Autophagy
  764. Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
  765. AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy
  766. Autophagy: shaping the tumor microenvironment and therapeutic response
  767. Autophagy in the Lung
  768. Autophagy and antigen presentation
  769. Atg7-dependent Autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophil
  770. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and Autophagy
  771. The induction of Autophagy by γ‐radiation contributes to the radioresistance of glioma stem cells
  772. Apoptosis and Autophagy: Regulation of caspase‐9 by phosphorylation
  773. TRAF6 and A20 Regulate Lysine 63–Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy
  774. Autophagy regulation and its role in cancer
  775. Role of non-canonical Beclin 1-independent Autophagy in cell death induced by resveratrol in human breast cancer cells
  776. Methods for detecting Autophagy and determining Autophagy–induced cell death
  777. Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast
  778. Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
  779. ER stress–mediated Autophagy promotes Myc-dependent transformation and tumor growth
  780. AMPK‐mediated Autophagy inhibits apoptosis in cisplatin‐treated tumour cells
  781. Atg22 Recycles Amino Acids to Link the Degradative and Recycling Functions of Autophagy
  782. Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection
  783. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
  784. Autophagy as a therapeutic target in cardiovascular disease
  785. Proteasome inhibitors activate Autophagy as a cytoprotective response in human prostate cancer cells
  786. Induction of Autophagy Promotes Fusion of Multivesicular Bodies with Autophagic Vacuoles in K562 Cells
  787. Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival
  788. A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1
  789. Alpha-alumina nanoparticles induce efficient Autophagy-dependent cross-presentation and potent antitumour response
  790. Application and interpretation of current Autophagy inhibitors and activators
  791. Modification of Cellular Autophagy Protein LC3 by Poliovirus
  792. Inactivation of the Autophagy Gene bec-1 Triggers Apoptotic Cell Death in C. elegans
  793. Autophagy in cellular metabolism and cancer
  794. Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease
  795. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
  796. Induction of ROS, mitochondrial damage and Autophagy in lung epithelial cancer cells by iron oxide nanoparticles
  797. Chaperone-mediated Autophagy in health and disease
  798. Autophagy in health and disease. 3. Involvement of Autophagy in muscle atrophy
  799. Oxidative stress and Autophagy in cardiac disease, neurological disorders, aging and cancer
  800. Selective types of Autophagy
  801. Selective Autophagy
  802. Autophagy is required for necrotic cell death in Caenorhabditis elegans
  803. Dopamine Oxidation and Autophagy
  804. Autophagy: Paying Charon’s Toll
  805. Self and Nonself: How Autophagy Targets Mitochondria and Bacteria
  806. Autophagy as a cell-repair mechanism: Activation of chaperone-mediated Autophagy during oxidative stress
  807. Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
  808. Connections between SNAREs and Autophagy
  809. Emerging strategies to effectively target Autophagy in cancer
  810. Pharmacological modulation of Autophagy: therapeutic potential and persisting obstacles
  811. Guidelines for the use and interpretation of assays for monitoring Autophagy in higher eukaryotes
  812. The endoplasmic reticulum in apoptosis and Autophagy: role of the BCL-2 protein family
  813. Autophagy, polyphenols and healthy ageing
  814. Autophagy in neuroprotection and neurodegeneration: a question of balance
  815. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote Autophagy
  816. Hypoxia signals Autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
  817. The role of autophagy in tumour development and cancer therapy
  818. Autophagy in cutaneous malignant melanoma
  819. Sulforaphane Causes Autophagy to Inhibit Release of Cytochrome c and Apoptosis in Human Prostate Cancer Cells
  820. Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and Autophagy
  821. Toll-like receptors in control of immunological Autophagy
  822. Protein Kinase A and Sch9 Cooperatively Regulate Induction of Autophagy in Saccharomyces cerevisiae
  823. Selective Autophagy in budding yeast
  824. Class III PI3K Vps34 plays an essential role in Autophagy and in heart and liver function
  825. Small molecule enhancers of Autophagy for neurodegenerative diseases
  826. Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
  827. Autophagy and mitophagy in cellular damage control
  828. Chaperone-Mediated Autophagy
  829. Organelle-Specific Initiation of Autophagy
  830. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced Autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
  831. Autophagy in Drosophila melanogaster
  832. Guidelines for the use and interpretation of assays for monitoring Autophagy (3rd edition)
  833. Membrane Origin for Autophagy
  834. Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
  835. Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma
  836. Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for Autophagy
  837. Toward unraveling membrane biogenesis in mammalian Autophagy
  838. Mechanisms of Autophagy Initiation
  839. All-you-can-eat: Autophagy in neurodegeneration and neuroprotection
  840. A Novel Protein Complex Linking the δ2 Glutamate Receptor and Autophagy: Implications for Neurodegeneration in Lurcher Mice
  841. Apg9p/Cvt7p Is an Integral Membrane Protein Required for Transport Vesicle Formation in the Cvt and Autophagy Pathways
  842. Apg14p and Apg6/Vps30p Form a Protein Complex Essential for Autophagy in the Yeast, Saccharomyces cerevisiae
  843. The class III PI(3)K Vps34 promotes Autophagy and endocytosis but not TOR signaling in Drosophila
  844. Life, death and burial: multifaceted impact of Autophagy
  845. Glycogen Autophagy
  846. Autophagy in human tumors: cell survival or death?
  847. Quantum Dots for Human Mesenchymal Stem Cells Labeling. A Size-Dependent Autophagy Activation
  848. Autophagy and cancer – issues we need to digest
  849. Feedback on Fat: p62-mTORC1-Autophagy Connections
  850. Monitoring and Measuring Autophagy
  851. Nutrient-dependent regulation of Autophagy through the target of rapamycin pathway
  852. Neuronal Autophagy in experimental scrapie
  853. Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress
  854. Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
  855. Human IRGM regulates Autophagy and cell-autonomous immunity functions through mitochondria
  856. Role of the Apg12 conjugation system in mammalian Autophagy
  857. Autophagy in C. elegans
  858. Prorenin Receptor Is Essential for Podocyte Autophagy and Survival
  859. Autophagy after Experimental Intracerebral Hemorrhage
  860. ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy
  861. Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer
  862. Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming
  863. Targeting Autophagy in neurodegenerative diseases
  864. Identification of Regulators of Chaperone-Mediated Autophagy
  865. Runx1 prevents wasting, myofibrillar disorganization, and Autophagy of skeletal muscle
  866. Autophagy and cell death
  867. Autophagy in aging, disease and death: the true identity of a cell death impostor
  868. Autophagy Contributes to Leaf Starch Degradation
  869. Targeting Autophagy during cancer therapy to improve clinical outcomes
  870. Autophagy: More Than a Nonselective Pathway
  871. Immunologic manifestations of Autophagy
  872. Azithromycin blocks Autophagy and may predispose cystic fibrosis patients to mycobacterial infection
  873. Cellular and metabolic functions for Autophagy in cancer cells
  874. Autophagy as a pro‐death pathway
  875. Mitochondria regulate Autophagy by conserved signalling pathways
  876. Autophagy in Vascular Disease
  877. Autophagy: a druggable process that is deregulated in aging and human disease
  878. The regulation of aging: does Autophagy underlie longevity?
  879. Turnover of organelles by Autophagy in yeast
  880. Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis
  881. Cleaning House: Selective Autophagy of Organelles
  882. Therapeutic Targeting of Autophagy
  883. Interactions of Pathogenic Bacteria with Autophagy Systems
  884. PLIC proteins or ubiquilins regulate Autophagy‐dependent cell survival during nutrient starvation
  885. Autophagy proteins in macroendocytic engulfment
  886. Constitutive Autophagy: vital role in clearance of unfavorable proteins in neurons
  887. Endocytosis and Autophagy: Shared machinery for degradation
  888. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
  889. Autophagy in organelle homeostasis: Peroxisome turnover
  890. Regulation of Autophagy in human and murine cartilage: Hypoxia‐inducible factor 2 suppresses chondrocyte Autophagy
  891. Inhibition of Autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells
  892. Autophagy as a target for cancer therapy: new developments
  893. Hypoxia-activated Autophagy accelerates degradation of SQSTM1/p62
  894. The role of PI3K/AKT/mTOR pathway in the modulation of Autophagy and the clearance of protein aggregates in neurodegeneration
  895. Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance
  896. The molecular mechanism of mitochondria Autophagy in yeast
  897. Reversal of Autophagy dysfunction in the TgCRND8 mouse model of Alzheimer’s disease ameliorates amyloid pathologies and memory deficits
  898. Induction of Autophagy is essential for monocyte-macrophage differentiation
  899. Autophagy takes flight inDrosophila
  900. Chapter 2 Methods for Monitoring Autophagy Using GFP‐LC3 Transgenic Mice
  901. Induction of Autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
  902. Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
  903. Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response in Arabidopsis
  904. Autophagy and ethanol-induced liver injury
  905. Autophagy and mitophagy in diabetic cardiomyopathy
  906. Metabolic Stress in Autophagy and Cell Death Pathways
  907. Autophagy in disease: a double-edged sword with therapeutic potential
  908. Autophagy as a mediator of chemotherapy-induced cell death in cancer
  909. AMPK-independent induction of Autophagy by cytosolic Ca2+ increase
  910. Autophagy regulates inflammation in adipocytes
  911. Autophagy: molecular machinery, regulation, and implications for renal pathophysiology
  912. Expression of beclin‐1, an Autophagy‐related protein, in gastric and colorectal cancers
  913. CD40 induces macrophage anti–Toxoplasma gondii activity by triggering Autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes
  914. Autophagy and misfolded proteins in neurodegeneration
  915. The late stages of Autophagy: how does the end begin?
  916. Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes
  917. Cadmium-induced Autophagy and apoptosis are mediated by a calcium signaling pathway
  918. The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
  919. Autophagy and bacterial infectious diseases
  920. Autophagy in Atherosclerosis
  921. Autophagy and Viruses: Adversaries or Allies?
  922. Mitochondrial Autophagy and injury in the liver in α1-antitrypsin deficiency
  923. TOR Is a Negative Regulator of Autophagy in Arabidopsis thaliana
  924. Steroid‐triggered death by Autophagy
  925. Autophagy, the Trojan horse to combat glioblastomas
  926. Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells
  927. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of Autophagy during lumen formation in vitro
  928. Endosome Sorting and Autophagy Are Essential for Differentiation and Virulence of Leishmania major
  929. Mechanism and medical implications of mammalian Autophagy
  930. Cell death and Autophagy: Cytokines, drugs, and nutritional factors
  931. Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress
  932. Quantitative relationship between Autophagy and proteolysis during graded amino acid deprivation in perfused rat liver.
  933. Organellophagy: Eliminating cellular building blocks via selective Autophagy
  934. Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy
  935. Atomistic Autophagy: The Structures of Cellular Self-Digestion
  936. The IP3 receptor–mitochondria connection in apoptosis and Autophagy
  937. Nutrient Sensing, Autophagy, and Diabetic Nephropathy
  938. Aging and Autophagy in the Heart
  939. Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis
  940. Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by Autophagy: pathophysiological implications
  941. Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA
  942. Autophagy, cell death, and cancer
  943. Autophagy and endocrine resistance in breast cancer
  944. Autophagy in MHC class II antigen processing
  945. At the end of the autophagic road: an emerging understanding of lysosomal functions in Autophagy
  946. Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
  947. Targeting cancer cells through Autophagy for anticancer therapy
  948. Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification
  949. Subversion of cellular Autophagy by Anaplasma phagocytophilum
  950. Autophagy as a new therapeutic target in Duchenne muscular dystrophy
  951. Autophagy and viral neurovirulence
  952. The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
  953. Leucine-rich repeat kinase 2 regulates Autophagy through a calcium-dependent pathway involving NAADP
  954. Autophagy – An Emerging Anti-Aging Mechanism
  955. Autophagy in Pulmonary Diseases
  956. Tau degradation: The ubiquitin–proteasome system versus the Autophagy-lysosome system
  957. Degradation of lipid droplet-associated proteins by chaperone-mediated Autophagy facilitates lipolysis
  958. Review: Autophagy in neurodegeneration: firefighter and/or incendiarist?
  959. Chikungunya virus–induced Autophagy delays caspase-dependent cell death
  960. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
  961. Accelerated Cell Death in Podospora Autophagy Mutants
  962. Multiple regulatory and effector roles of Autophagy in immunity
  963. Chaperone-mediated Autophagy: machinery, regulation and biological consequences
  964. ANG II promotes Autophagy in podocytes
  965. Protective Role of Autophagy in Palmitate-Induced INS-1 β-Cell Death
  966. Midbody ring disposal by Autophagy is a post-abscission event of cytokinesis
  967. Autophagy in the immune system
  968. Cardioprotection by Endoplasmic Reticulum Stress–Induced Autophagy
  969. MiR-30-Regulated Autophagy Mediates Angiotensin II-Induced Myocardial Hypertrophy
  970. Chapter 19 Methods to Monitor Chaperone‐Mediated Autophagy
  971. MAPK/JNK signalling: a potential Autophagy regulation pathway
  972. Mitochondrial Ca2+ signals in Autophagy
  973. Regulation and Function of Autophagy during Cell Survival and Cell Death
  974. Autophagy inhibitors
  975. Free Radicals in Cross Talk Between Autophagy and Apoptosis
  976. Autophagy Preceded Apoptosis in Oridonin-Treated Human Breast Cancer MCF-7 Cells
  977. Autophagy in hypoxia-ischemia induced brain injury
  978. Autophagy in intracellular bacterial infection
  979. Autophagy in unicellular eukaryotes
  980. Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways
  981. Autophagy and innate immunity: Triggering, targeting and tuning
  982. Autophagy is essential for effector CD8+ T cell survival and memory formation
  983. Molecular Mechanisms of Autophagy in the Cardiovascular System
  984. Cytotoxic Autophagy in Cancer Therapy
  985. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the Autophagy/multivesicular body pathways
  986. New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and Autophagy
  987. The cell biology of Autophagy in metazoans: a developing story
  988. Understanding Autophagy in Cell Death Control
  989. The receptor for advanced glycation end products (RAGE) sustains Autophagy and limits apoptosis, promoting pancreatic tumor cell survival
  990. Erk1/2-dependent Phosphorylation of Gα-interacting Protein Stimulates Its GTPase Accelerating Activity and Autophagy in Human Colon Cancer Cells
  991. Autophagy in innate and adaptive immunity against intracellular pathogens
  992. Regulation of Liver Metabolism by Autophagy
  993. Author Correction: Autophagy maintains tumour growth through circulating arginine.
  994. Biological Functions of Autophagy Genes: A Disease Perspective
  995. RNA binding to p62 impacts selective Autophagy
  996. Intersections between Regulated Cell Death and Autophagy
  997. Ubiquitination of MAP1LC3B by pVHL is associated with Autophagy and cell death in renal cell carcinoma
  998. Autophagy without conjugation
  999. Chapter 16 – Autophagy and Autoimmunity
  1000. Autophagy in the Heart

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