PILLARS OF LONGEVITY

NAD+

NAD+ kinase—a review A methanol/dioxygen biofuel cell that uses NAD+-dependent dehydrogenases as catalysts: application of an electro-enzymatic method to regenerate nicotinamide … Glyceraldehyde-3-phosphate Dehydrogenase Selectively Binds AU-rich RNA in the NAD+-binding Region (Rossmann Fold)(∗) Activities of citrate synthase and NAD+-linked and NADP+-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates Structural determination of a cyclic […]

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INHIBITION OF ADVANCED GLYCATION END PRODUCTS

Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity Extract of Cassiae semen attenuates diabetic nephropathy via Inhibition of advanced glycation end products accumulation in streptozotocin-induced diabetic rats The extract of Litsea japonica reduced the development of diabetic nephropathy via the Inhibition of advanced glycation end products accumulation in

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NEUTRALIZING OXIDATIVE STRESS WITH MEDICINAL PLANTS

OXIDATIVE STRESS and antioxidant potential of one hundred MEDICINAL PLANTS A review of OXIDATIVE STRESS in acute kidney injury: protective role of MEDICINAL PLANTS-derived antioxidants Ethnobotanical study of MEDICINAL PLANTS used by traditional healers for the treatment of OXIDATIVE STRESS-related diseases in the Congo Basin Effects of extracts of selected MEDICINAL PLANTS upon hepatic OXIDATIVE

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EXTENDS LIFESPAN

Overexpression of Atg5 in mice activates autophagy and extends lifespan Rapamycin fed late in life extends lifespan in genetically heterogeneous mice Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans Dietary deprivation extends lifespan in Caenorhabditis elegans An antidepressant that extends lifespan in adult Caenorhabditis elegans rAAV6-microdystrophin preserves muscle function and extends lifespan in severely

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NEUROPROTECTIVE AGENTS

Neuroprotection by estradiol Neuroprotection by the inhibition of apoptosis The problem of assessing effective Neuroprotection in experimental cerebral ischemia Perinatal brain injury: from pathogenesis to Neuroprotection Nerve growth factor signaling, Neuroprotection , and neural repair Neuroprotection by the metabolic antioxidant α-lipoic acid Adenosine and Neuroprotection Estrogens and Neuroprotection Erythropoietin–a novel concept for Neuroprotection Antioxidant Neuroprotection

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CALORIE RESTRICTION

Calorie restriction—the SIR2 connection How does calorie restriction work? Calorie restriction and aging: review of the literature and implications for studies in humans Aging, adiposity, and calorie restriction Calorie restriction and SIR2 genes—towards a mechanism Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Sir2-independent life span extension by calorie

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METHIONINE RESTRICTION

A review of METHIONINE dependency and the role of METHIONINE Restriction in cancer growth control and life-span extension Life-span extension in mice by preweaning food Restriction and by METHIONINE Restriction in middle age Exploiting METHIONINE Restriction for cancer treatment The low-METHIONINE content of vegan diets may make METHIONINE Restriction feasible as a life extension strategy

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NEUROGENESIS (GROWING NEW BRAIN CELLS)

Regressive events in Neurogenesis Stress and hippocampal Neurogenesis Vascular niche for adult hippocampal Neurogenesis Neurogenesis in the adult human hippocampus Limits of Neurogenesis in primates Neurogenesis in the adult is involved in the formation of trace memories Autoradiographic and histological evidence of postnatal hippocampal Neurogenesis in rats Adult brain Neurogenesis and psychiatry: a novel theory

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IRISIN

A comparative study on the effects of high-fat diet and endurance training on the PGC-1α-FNDC5/Irisin pathway in obese and nonobese male C57BL/6 mice A COMPARISON OF THE EFFECTS OF RESISTANCE AND ENDURANCE TRAINING PROTOCOLS ON SERUM Irisin LEVEL AND ALKALINE … A comprehensive immunohistochemical examination of the distribution of the fat-burning protein Irisin in biological

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