PILLARS OF LONGEVITY

INTERMITTENT FASTING

Here’s the LIFE CHANGING 22/2 intermittent fasting protocol:  đŸ’„MORNING Cognitive enhancement Trinity 1/4 tsp  Autonomous 1/8 tsp (very strong start small)  Seven Sages (sold separately) 1/4 tsp (if you feel good increase to 1/2 tsp)  Matcha 1/4 tsp (too much at once may make you feel nauseous; very strong matcha)  Jing Force 1/4 tsp  Glucose […]

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MITOCHONDRIAL UNCOUPLING

The biology of Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling-protein homologues Mitochondrial Uncoupling proteins—what is their physiological role? Superoxide activates Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling proteins Transport function and regulation of Mitochondrial Uncoupling proteins 2 and 3 Ageing, oxidative stress, and Mitochondrial Uncoupling Mitochondrial Uncoupling proteins in the CNS: in support of function and survival

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HORMESIS

Hormesis defined Radiation Hormesis Hormesis in aging Hormesis: why it is important to toxicology and toxicologists Hormesis and medicine Hormesis with ionizing radiation Hormesis as a biological hypothesis. Hormesis: the dose-response revolution Hormesis and plant biology Improved empirical models describing Hormesis Is Hormesis an evolutionary expectation? Exercise, oxidative stress and Hormesis A theory for growth

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Nrf2

Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models Abstract Studying long-lived animals provides novel insight into shared characteristics of aging and represents a unique model to elucidate approaches to prevent chronic disease. Oxidant stress underlies many chronic diseases and resistance to stress is a potential mechanism governing slowed aging. The transcription factor

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ADVANCED GLYCATION END PRODUCTS (AGES)

Advanced glycation end products Key players in skin aging? Abstract Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging

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LIFESPAN EXTENSION

“Ashwagandha”–This Ancient Indiant Plant Completely Rebuilds Your Brain & extend Lifespan 10-Hydroxy-2-Decenoic Acid, The Major Lipid Component Of Royal Jelly, extends The Lifespan Of Caenorhabditis Elegans Through Dietary Restriction And Target Of 
 2-Secd Treatment extends Lifespan, Improves Healthspan And Enhances Resistance To Stress In Caenorhabditis Elegans 35. Systemic Administration Of Raav6-Microdystrophin Preserves Muscle Function

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CENTENARIANS

(Cd45Ra+) And Memory (Cd45R0+) Cells Between Cd4+ And Cd8+ Lymphocytes-T In Humans-A Study From Newborns To Centenarians 166: Out-Of-Hospital Cardiac Arrest (Ohca) In Centenarians In Japan 56Demographics Of Centenarians Admitted Through Medical Receiving In Raigmore Hospital A Baseline Investigation Of Independence Among 100 Community-Dwelling Centenarians In Turkey A Census‐Based Comparison Of Centenarians In New Zealand

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HSP90

Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a number of proteins required for tumor growth, which is why Hsp90 inhibitors are investigated as anti-cancer drugs. Heat shock proteins, as a class, are among the most highly expressed cellular proteins across all species.[3] As their name

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Klotho

Klotho is a transmembrane protein that, in addition to other effects, provides some control over the sensitivity of the organism to insulin and appears to be involved in ageing. Its discovery was documented in 1997 by Makoto Kuro-o et al.[9] The name of the gene comes from Klotho or Clotho, one of the Moirai, or

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FGF21

Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses. Fibroblast growth factor 21 (FGF21) is a hormone-like member of FGF family which controls metabolic multiorgan crosstalk enhancing energy expenditure through glucose and lipid metabolism. In addition, FGF21 acts as a stress hormone induced by endoplasmic reticulum stress and dysfunctions of mitochondria and

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