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SUPER TONIC HAIR

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SUPER TONIC HAIR


Goes great with

PINE POLLEN

1 tbs a day!


200:1 Concentration

100 Grams

Inhibit Gray | Promote Growth

Directions: Start 1-2 tsp a day for 2 weeks then maintain with 1/4-1/2 tsp daily.

Pairs perfectly with Interstellar Pine Pollen, Spice and Peel.

Featuring:

Andrographolide (Andrographis paniculata) • Anthocyanins • Apigenin • Arctigenin (from Fructus Arctii) • Asiasari radix • Astragali radix • Baicalin • Brazilian propolis extract powder • Buxus wallichiana Baill (Buxaceae) • Capparis spinosa L extract • Carnosol • Ceratonia siliqua pod extract • Chrysanthemum zawadskii • Cordycepin • Cranberry peel extract • Curcumin • Cyanidin • Cycloastragenol • DHEA • Dragon’s Blood from Croton lechleri • Eclipta prostrata • EGCG • Ellagic acid • Emodin • Equisetum arvense • Fermented barley extract • Ferulic acid • Fucoxanthin • Ginseng radix • Glycyrrhiza glabra root extract • Grape seed proanthocyanidin extract • Hesperidin • Hibiscus rosa-sinensis L. flowers • Houttuynia cordata • Hydroxytyrosol • Icariin • Isorhapontigenin • kaempferol • Kolaviron • Kurarinone (From roots of Sophora • Ligustri fructus • Lonicera japonica flower extract • Luteolin • Metasequoia glyptostroboides leaves &bark extract • Myricetin • N-acetyl- glucosamine • Naringenin • Naringin • Paeoniflorin • Perilla frutescens var. acuta (PFVA) • Pinocembrin • Piper nigrum extract (Piperaceae) • Plectranthus barbatus extract • Polyporus umbellatus • Pomegranate peel extract • Procyanidins from apple peel • Psoralea corylifolia (psoralidin) • Pterostilbene • Quercetin • Radix Angelicae sinensis • Rehmannia glutinosa • Resveratrol • Sanguisorba officinalis • Silibinin • Sophora flavescens root • Tripterygium wilfordii (Celastrol) extract triptolide • Ursolic acid • Urtica dioica



Age‐induced hair greying – the multiple effects of oxidative stress

An obvious sign of ageing is hair greying, or the loss of pigment production and deposition within the hair shafts. Numerous mechanisms, acting at different levels and follicular locations, contribute to hair greying, ranging from melanocyte stem cells defects to follicular melanocyte death. One key issue that is in common to these processes is oxidative damage. At the hair follicle stem cells niche, oxidative stress, accelerated by B‐cell lymphoma 2 gene (BCL‐2) depletion, leads to selective apoptosis and diminution of melanocyte stem cells, reducing the repopulation of newly formed anagen follicles. Melanotic bulbar melanocytes express high levels of BCL‐2 to enable survival from melanogenesis‐ and ultraviolet A (UVA)‐induced reactive oxygen species (ROS) attacks. With ageing, the bulbar melanocyte expression of anti‐oxidant proteins such as BCL‐2, and possibly TRP‐2, is reduced, and the dedicated enzymatic anti‐oxidant defence system throughout the follicle weakens, resulting in enhanced oxidative stress. A marked reduction in catalase expression and activity results in millimolar accumulation of hydrogen peroxide, contributing to bulbar melanocyte malfunction and death. Interestingly, amelanotic melanocytes at the outer root sheath (ORS) are somewhat less affected by these processes and survive for longer time even within the white, ageing hair follicles. Better understanding of the overtime susceptibility of melanocytes to oxidative stress at the different follicular locations might yield clues to possible therapies for the prevention and reversal of hair greying.


Oxidative Stress in Ageing of Hair

Experimental evidence supports the hypothesis that oxidative stress plays a major role in the ageing process. Reactive oxygen species are generated by a multitude of endogenous and environmental challenges. Reactive oxygen species or free radicals are highly reactive molecules that can directly damage cellular structural membranes, lipids, proteins, and DNA. The body possesses endogenous defence mechanisms, such as antioxidative enzymes and non-enzymatic antioxidative molecules, protecting it from free radicals by reducing and neutralizing them. With age, the production of free radicals increases, while the endogenous defence mechanisms decrease. This imbalance leads to the progressive damage of cellular structures, presumably resulting in the ageing phenotype. Ageing of hair manifests as decrease of melanocyte function or graying, and decrease in hair production or alopecia. There is circumstantial evidence that oxidative stress may be a pivotal mechanism contributing to hair graying and hair loss. New insights into the role and prevention of oxidative stress could open new strategies for intervention and reversal of the hair graying process and age-dependent alopecia.

Age-induced hair graying (canities), or the age-induced loss of melanin synthesis and deposition within the hair shafts, is a noticeable and undesired sign of the aging process. Numerous mechanisms contribute to age-induced hair graying, affecting both follicular and stem cell melanocytes and acting at different follicular locations. Many of these processes are induced, directly or indirectly, by oxidative insults and damage. Melanin-producing bulbar melanocytes express high levels of BCL-2 to survive reactive oxygen species (ROS) attacks, which are induced by the melanogenic process itself and by ultraviolet A (UVA) irradiation. With aging, the expression of BCL-2, and possibly of TRP-2, is reduced, and the endogenous, enzymatic antioxidant defense system declines, resulting in greater oxidative stress. In particular, catalase expression and activity are markedly reduced with aging, leading to millimolar accumulation of hydrogen peroxide within the hair follicle and contributing to bulbar melanocyte failure and death. Additionally, exposure of melanocyte stem cells to cumulative oxidative damage, combined with reduced BCL-2 protective levels, results in apoptosis and therefore decreases the number of melanocytes that could repopulate the newly formed anagen follicles. Altogether, oxidative stress may contribute to age-induced hair graying via multiple pathways. Better understanding of the different processes, sources, and types of oxidative stress within the follicular environment, and the different susceptibilities of melanocytes to oxidative stress at the different follicular locations, might yield clues to possible interventions for prevention or reversal of hair graying.


Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage

Here we provide unique evidence for oxidative stress induced loss of melanocytes from the human hair follicle during aging. In detail, we show for the first time that:1)a decreased number of viable melanocytes in the aging hair follicle bulge and bulb and an increased incidence of hair bulb melanocyte apoptosis in aging individuals are associated with oxidative stress in the pigmentary unit;2)the aging hair follicle is characterized by the absence of oxidative stress-protectors, such as Bcl-2, and melanocyte growth factors, such as c-Kit;3)a higher frequency of oxidative stress associated mitochondrial DNA damage occurs in graying hair follicles, while unpigmented hair follicles prove to be not “older” than pigmented hair follicles;4)melanocytes of the pigmentary unit are highly and selectively susceptible to exogenous oxidative stress damage.One major route, by which oxidative stress leads to permanent melanocyte damage, appears to pass by the mitochondria, since their DNA is not so well protected as genomic DNA. The accumulation of mutations, therefore, correlates with age and is indicative of general exposure and generation of oxidative stress, (39, 40)caused for example by psychoemotional stress, inflammation, UV-light, and others. In summary, our findings support the proposed hypothesis of a “free radical theory of graying” and suggest that melanocytes in the hair follicle are highly susceptible to endogenous oxidative stress. Exogenous oxidative stress can trigger and hasten this process and provoke permanent damage selectively and prematurely in hair bulb melanocytes.


Age-related hair pigment loss.

Humans are social animals that communicate disproportionately via potent genetic signals imbued in the skin and hair, including racial, ethnic, health, gender, and age status. For the vast majority of us, age-related hair pigment loss becomes the inescapable signal of our disappearing youth. The hair follicle (HF) pigmentary unit is a wonderful tissue for studying mechanisms generally regulating aging, often before this becomes evident elsewhere in the body. Given that follicular melanocytes (unlike those in the epidermis) are regulated by the hair growth cycle, this cycle is likely to impact the process of aging in the HF pigmentary unit. The formal identification of melanocyte stem cells in the mouse skin has spurred a flurry of reports on the potential involvement of melanocyte stem cell depletion in hair graying (i.e., canities). Caution is recommended, however, against simple extrapolation of murine data to humans. Regardless, hair graying in both species is likely to involve an age-related imbalance in the tissue’s oxidative stress handling that will impact not only melanogenesis but also melanocyte stem cell and melanocyte homeostasis and survival. There is some emerging evidence that the HF pigmentary unit may have regenerative potential, even after it has begun to produce white hair fibers. It may therefore be feasible to develop strategies to modulate some aging-associated changes to maintain melanin production for longer.


Chronic inflammation induces telomere dysfunction and accelerates ageing

Chronic inflammation is associated with normal and pathological ageing. Here we show that chronic, progressive low-grade inflammation induced by knockout of the nfkb1subunit of the transcription factor NF-κB induces premature ageing in mice. We also show that these mice have reduced regeneration in liver and gut. nfkb1−/−fibroblasts exhibit aggravated cell senescence because of an enhanced autocrine and paracrine feedback through NF-κB, COX-2 and ROS, which stabilizes DNA damage. Preferential accumulation of telomere-dysfunctional senescent cells in nfkb1−/−tissues is blocked by anti-inflammatory or antioxidant treatment of mice, and this rescues tissue regenerative potential. Frequencies of senescent cells in liver and intestinal crypts quantitatively predict mean and maximum lifespan in both short- and long-lived mice cohorts. These data indicate that systemic chronic inflammation can accelerate ageing via ROS-mediated exacerbation of telomere dysfunction and cell senescence in the absence of any other genetic or environmental factor.


Aging is associated with circulating cytokine dysregulation

Aging has a significant impact on the production of circulating cytokines in healthy individuals. The circulating cytokine milieu may contribute to the development of age-restricted conditions. ► Aging has a significant impact on the production of circulating cytokines. ► Cytokines dysregulation is demonstrated ex vivo but not after in vitro activation. ► Pro- and anti-inflammatory cytokines correlate with aging. ► Th1 cytokines increase whereas Th17 cytokines decrease with age.


Repigmentation and new growth of hairs after anti–interleukin-17 therapy

Repigmentation of hairs is a rare event that has been reported after inflammatory processes, exposure to X-irradiation and psoralen and ultraviolet A, electron beam therapy, and the intake of some drugs. We report on a patient with psoriasis who experienced darkening and noticeable increase in scalp hair while he was receiving anti–interleukin (IL)-17 therapy.


Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor

Using RNA in situ hybridization analysis, we have characterized the expression domains of the four known members of the FGF receptor-tyrosine kinase gene family in the murine hair follicle at various stages of the hair growth cycle. During anagen, we detected Fgfr1 RNA in the dermal papilla, Fgfr2 RNA in hair matrix cells near the dermal papilla, Fgfr3 RNA in pre-cuticle cells in the periphery of the hair bulb, and Fgfr4 RNA in cells in the periphery of the hair bulb and also in the inner and outer root sheath in the lower half of the follicle neck. No RNA expression of these genes was detected during late catagen or telogen. We have previously shown that Fgf5 is expressed in the outer root sheath in the transient portion of the follicle (Hébert et al. [1994] Cell 78:1017-1025). In the present study we have also assayed for the expression of six other members of the FGF ligand gene family, Fgf3, Fgf4, Fgf6, Fgf7, Fgf8, and Fgf9. Among these FGF genes, only Fgf7 was found to be expressed in the hair follicle. Fgf7 RNA is localized to the dermal papilla during anagen, but expression is down-regulated by the late-anagen VI stage. We have also demonstrated that addition of FGF5 protein to the culture medium changes the behavior of dermal papilla cells in vitro, indicating that they are capable of responding to FGF5. Together with previously published data, these results provide a complete analysis of FGF ligand and FGF receptor-tyrosine kinase gene expression in the hair follicle, and suggest that FGF signalling may have several functions in the hair growth cycle


Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 & FGF-5

Hair shaft producing cells were proliferated only in the anagen. Many mediators were involved in starting, sustaining and terminating anagen. Among them, we focused on the growth factor FGF-7 and FGF-5. Our results reveal the hair growth enhancing effects of EP were related with the anagen regulating growth factors. mTOR activating the potential of EP in HDPs was signifying that it exerts the positive role in the proliferation of follicular cells during anagen.


FGF5 is a crucial regulator of hair length in humans

Hair length varies dramatically on different body sites and also varies between individuals. Thus, hair length is a quantitative trait, suggesting inherited differences. In this study, we obtained DNA from families segregating excessively long eyelashes consistent with an autosomal recessive trait. We identified mutations in a single gene, fibroblast growth factor 5 (FGF5), which was homozygous in affected family members only. FGF5 has previously been implicated as a regulator of hair lengths in mammals, with mutations resulting in the well-described angoraphenotype. However, until now a human counterpart to this phenotype remained elusive. Here, we present, to our knowledge, the first human counterpart of the angoraphenotype, showing that FGF5 underlies trichomegaly and is a crucial regulator of hair growth in humans.


Oxidative stress management in the hair follicle: Targeting NRF2 counter age‐related hair disorders and beyond

Widespread expression of the transcription factor, nuclear factor (erythroid‐derived 2)‐like 2 (NRF2), which maintains redox homeostasis, has recently been identified in the hair follicle (HF). Small molecule activators of NRF2 may therefore be useful in the management of HF pathologies associated with redox imbalance, ranging from HF greying and HF ageing via androgenetic alopecia and alopecia areata to chemotherapy‐induced hair loss. Indeed, NRF2 activation has been shown to prevent peroxide‐induced hair growth inhibition. Multiple parameters can increase the levels of reactive oxygen species in the HF, for example melanogenesis, depilation‐induced trauma, neurogenic and autoimmune inflammation, toxic drugs, environmental stressors such as UV irradiation, genetic defects and aging‐associated mitochondrial dysfunction. In this review, the potential mechanisms whereby NRF2 activation could prove beneficial in treatment of redox‐associated HF disorders are therefore discussed.


The impact of oxidative stress on hair

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system’s ability to detoxify the reactive intermediates or to repair the resulting damage. Reactive oxygen species or free radicals are highly reactive molecules that can directly damage lipids, proteins, and DNA. They are generated by a multitude of endogenous and environmental challenges, while the body possesses endogenous defense mechanisms. With age, production of free radicals increases, while the endogenous defense mechanisms decrease. This imbalance leads to progressive damage of cellular structures, presumably resulting in the aging phenotype. While the role of oxidative stress has been widely discussed in skin aging, little focus has been placed on its impact on hair condition. Moreover, most literature on age‐related hair changes focuses on alopecia, but it is equally important that the hair fibers that emerge from the scalp exhibit significant age‐related changes that have equal impact on the overall cosmetic properties of hair. Sources of oxidative stress with impact on the pre‐emerging fiber include: oxidative metabolism, smoking, UVR, and inflammation from microbial, pollutant, or irritant origins. Sources of oxidative stress with impact on the post‐emerging fiber include: UVR (enhanced by copper), chemical insults, and oxidized scalp lipids. The role of the dermatologist is recognition and treatment of pre‐ and post‐emerging factors for lifetime scalp and hair health.


Repigmentation of hair following adalimumab therapy

Repigmentation of canities, or age-related grey or white hair, is a rare occurrence. Generalized repigmentation of grey-white hair has been reported following inflammatory processes,[1] and heterochromia (localized patches of hair repigmentation) is even more unusual, reported in association with medication use and malignancy.Tumor necrosis factor (TNF) inhibitors are increasingly utilized medications for inflammatory disorders, including psoriasis, rheumatoid arthritis, and inflammatory bowel disease. Hair loss, or alopecia, has been described among the side effects of these medications,[2] but changes in hair pigmentation in association with this class of drugs have not previously been reported. We describe a patient with hair repigmentation associated with adalimumab therapy.


A Comment on the Science of Hair Aging

In contrast to the skin, aging of the hair has seemingly only recently found the attention of dermatological meetings, mainly promoted by the cosmetic industry for marketing purposes. In fact, basic scientists interested in the biology of hair growth and pigmentation have for some time already exposed the hair follicle as a highly accessible model with unique opportunities for the study of age-related effects. As a result, the science of hair aging focuses on two main streams of interest: the esthetic problem of aging hair and its management, in terms of age-related effects on hair color, quantity, and quality; and the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes underlying the aging process. Ultimately, the aim of hair anti-aging is to delay, lessen, or reverse the effects of aging on hair. According to the complex nature of the aging process, the treatment for lifetime scalp and hair health has to be holistic to include the multitude of contributing factors in a polyhedral and patient-specific manner. It comprises both medical treatments and hair cosmetics. Accordingly, the discovery of pharmacological targets and the development of safe and effective drugs for treatment of hair loss indicate strategies of the drug industry for maintenance of hair growth and quantity, while the hair care industry has become capable of delivering active compounds directed toward meeting the consumer demand for maintenance of hair cosmesis and quality. “Where there’s life, there’s hope” (Ecclesiastes 9:3-5).

 


Three Streams for the Mechanism of Hair Graying

Hair graying is an obvious sign of human aging. Although graying has been investigated extensively, the mechanism remains unclear. Here, we reviewed previous studies on the mechanism of graying and seek to offer some new insights. The traditional view is that hair graying is caused by exhaustion of the pigmentary potential of the melanocytes of hair bulbs. Melanocyte dysfunction may be attributable to the effects of toxic reactive oxygen species on melanocyte nuclei and mitochondria. A recent study suggests that bulge melanocyte stem cells (MSCs) are the key cells in play. Graying may be caused by defective MSC self-maintenance, not by any deficiency in bulbar melanocytes. Our previous study suggested that graying may be principally attributable to active hair growth. Active hair growth may produce oxidative or genotoxic stress in hair bulge. These internal stress may cause eventually depletion of MSC in the hair follicles. Taken together, hair graying may be caused by MSC depletion by genotoxic stress in the hair bulge. Hair graying may also be sometimes caused by dysfunction of the melanocytes by oxidative stress in the hair bulb. In addition, hair graying may be attributable to MSC depletion by active hair growth.


Pharmacologic interventions in aging hair

The appearance of hair plays an important role in people’s overall physical appearance and self-perception. With today’s increasing life-expectations, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this and is delivering active products directed towards meeting this consumer demand. The discovery of pharmacological targets and the development of safe and effective drugs also indicate strategies of the drug industry for maintenance of healthy and beautiful hair. Hair aging comprises weathering of the hair shaft, decrease of melanocyte function, and decrease in hair production. The scalp is subject to intrinsic and extrinsic aging. Intrinsic factors are related to individual genetic and epigenetic mechanisms with interindividual variation: prototypes are familial premature graying, and androgenetic alopecia. Currently available pharmacologic treatment modalities with proven efficacy for treatment of androgenetic alopecia are topical minoxidil and oral finasteride. Extrinsic factors include ultraviolet radiation and air pollution. Experimental evidence supports the hypothesis that oxidative stress also plays a role in hair aging. Topical anti-aging compounds include photoprotectors and antioxidants. In the absence of another way to reverse hair graying, hair colorants remain the mainstay of recovering lost hair color. Topical liposome targeting for melanins, genes, and proteins selectively to hair follicles are currently under investigation.


Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control

Stress has long been discussed controversially as a cause of hair loss. However, solid proof of stress‐induced hair growth inhibition had long been missing. If psychoemotional stress can affect hair growth, this must be mediated via definable neurorendocrine and/or neuroimmunological signaling pathways. Revisiting and up‐dating relevant background data on neural mechanisms of hair growth control, we sketch essentials of hair follicle (HF) neurobiology and discuss the modulation of murine hair growth by neuropeptides, neurotransmitters, neurotrophins, and mast cells. Exploiting an established mouse model for stress, we summarize recent evidence that sonic stress triggers a cascade of molecular events including plasticity of the peptidergic peri‐ and interfollicular innervation and neuroimmune crosstalk. Substance P (SP) and NGF (nerve growth factor) are recruited as key mediators of stress‐induced hair growth‐inhibitory effects. These effects include perifollicular neurogenic inflammation, HF keratinocyte apoptosis, inhibition of proliferation within the HF epithelium, and premature HF regression (catagen induction). Intriguingly, most of these effects can be abrogated by treatment of stressed mice with SP‐receptor neurokinin‐1 receptor (NK‐1) antagonists or NGF‐neutralizing antibodies – as well as, surprisingly, by topical minoxidil. Thus there is now solid in vivo‐evidence for the existence of a defined brain‐ HF axis. This axis can be utilized by psychoemotional and other stressors to prematurely terminate hair growth. Stress‐induced hair growth inhibition can therefore serve as a highly instructive model for exploring the brain‐skin connection and provides a unique experimental model for dissecting general principles of skin neuroendocrinology and neuroimmunology well beyond the HF.


Aging of hair

The appearance of hair plays an important role in people’s overall physical appearance and self‐perception. With today’s increasing life expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this and also more capable to deliver active products that are directed toward meeting this consumer demand. The discovery of pharmacological targets and the development of safe and effective drugs also indicate strategies of the drug industry for maintenance of healthy and beautiful hair. Hair aging comprises weathering of the hair shaft and aging of the hair follicle. The latter manifests as decrease of melanocyte function or graying, and decrease in hair production in androgenetic and senescent alopecia. The scalp is also subject to intrinsic or physiologic aging and extrinsic aging caused by external factors. Intrinsic factors are related to individual genetic and epigenetic mechanisms with interindividual variation. Prototypes are familial premature graying and androgenetic alopecia. Extrinsic factors include ultraviolet radiation and smoking. Experimental evidence supports the hypothesis that oxidative stress plays a role in skin and hair aging. Topical anti‐aging compounds for hair include humefactants, hair conditioners, photoprotectors, and antioxidants. Current available treatment modalities with proven efficacy for treatment of androgenetic alopecia are topical minoxidil, oral finasteride, and autologous hair transplantation. In the absence of another way to reverse hair graying, hair colorants are the mainstays of recovering lost hair color. Topical liposome targeting for melanins, genes, and proteins selectively to hair follicles are under current investigation.


Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging

The tight coupling of hair follicle melanogenesis to the hair growth cycle dramatically distinguishes follicular melanogenesis from the continuous melanogenesis of the epidermis. Cyclic re-construction of an intact hair follicle pigmentary unit occurs optimally in all scalp hair follicles during only the first 10 hair cycles, i.e. by approximately 40 years of age. Thereafter there appears to be a genetically regulated exhaustion of the pigmentary potential of each individual hair follicle leading to the formation of true gray and white hair. Pigment dilution results primarily from a reduction in tyrosinase activity within hair bulbar melanocytes. Thereafter, sub-optimal melanocyte–cortical keratinocyte interactions, and defective migration of melanocytes from a reservoir in the upper outer root sheath to the pigment-permitting microenvironment close to the follicular papilla of the hair bulb, will all disrupt normal function of the pigmentary unit. Evidence from studies on epidermal melanocyte aging suggest that reactive oxygen species-mediated damage to nuclear and mitochondrial DNA may lead to mutation accumulation in bulbar melanocytes. Parallel dysregulation of anti-oxidant mechanisms or pro/anti-apoptotic factors is also likely to occur within the cells. Pigment loss in canities may also affect keratinocyte proliferation and differentiation, providing the tantalizing suggestion that melanocytes in the hair follicle contribute far more that packages of pigment alone. Here, we review the current state of knowledge of the development, regulation and control of the aging human hair follicle pigmentary system in relation with hair cycling. The exploitation of recently available methodologies to manipulate hair follicle melanocytes in vitro, and the observations that melanocytes remain in senile white hair follicles that can be induced to pigment in culture, raises the possibility of someday reversing canities. The perspective of rejuvenation of the whole hair follicle apparatus are still part of the dream but optimising its functional properties is clinically relevant and is close to reality. Finally as hair color influences its visibility when optical methods such as scalp photography are used to count hair fibers, the attention is drawn to possible interpretations of statistically significant changes in visible hair. Such changes may not exclusively be related to improved hair growth itself but also to changes in natural hair color that makes the hair more visible with the method used to count hairs.


Human hair pigmentation – biological aspects

Skin and hair colour contribute significantly to our overall visual appearance and to social/sexual communication. Despite their shared origins in the embryologic neural crest, the hair follicle and epidermal pigmentary units occupy distinct, although open, cutaneous compartments. They can be distinguished principally on the basis of the former’s stringent coupling to the hair growth cycle compared with the latter’s continuous melanogenesis. The biosynthesis of melanin and its subsequent transfer from melanocyte to hair bulb keratinocytes depend on the availability of melanin precursors and on a raft of signal transduction pathways that are both highly complex and commonly redundant. These signalling pathways can be both dependent and independent of receptors, act through auto‐, para‐ or intracrine mechanisms and can be modified by hormonal signals. Despite many shared features, follicular melanocytes appear to be more sensitive than epidermal melanocytes to ageing influences. This can be seen most dramatically in hair greying/canities and this is likely to reflect significant differences in the epidermal and follicular microenvironments. The hair follicle pigmentary unit may also serve as an important environmental sensor, whereby hair pigment contributes to the rapid excretion of heavy metals, chemicals and toxins from the body by their selective binding to melanin; rendering the hair fibre a useful barometer of exposures. The recent availability of advanced cell culture methodologies for isolated hair follicle melanocytes and for intact anagen hair follicle organ culture should provide the research tools necessary to elucidate the regulatory mechanisms of hair follicle pigmentation. In the longer term, it may be feasible to develop hair colour modifiers of a biological nature to accompany those based on chemicals.


Histopathology of aging of the hair follicle

Hair follicles experience several changes with aging, the most noticeable of which is graying of the hair shaft due to loss of melanin. Additional changes in the diameter and length of the hair have contributed to the concept of senescent alopecia, which is different from androgenetic alopecia according to most. Graying happens in most individuals, although in different grades and starting at different ages. It is related to a decrease in the number and activity of the melanocytes of the hair bulb, which eventually completely disappear from the bulb of the white hair. Residual non‐active melanocytes remain in the outer root sheath and in the bulge, which allows for repigmentation of the hair under certain stimuli or conditions.


A review of the etiologies, clinical characteristics, and treatment of grey hair

Hair pigmentation is regulated by follicular melanogenesis, in which the process consists of melanin formation and transfer to keratinocytes in the hair shaft. Human hair follicles contain two types of melanin: the brown‐black eumelanin and yellow‐red pheomelanin. Eumelanin is commonly present in black and brown hair while pheomelanin is found in auburn and blonde hair. Hair follicle melanogenesis is under cyclical control and is concurrently coupled to hair growth. Many factors including intrinsic and extrinsic factors affect the follicular melanogenesis. Though many studies have been conducted to identify the pathogenesis and regulation of hair pigmentation, the etiology of canities and hair pigmentation is still unclear. The pathogenesis of canities or gray hair is believed to occur either from insufficient melanin formation due to melanocyte degeneration or a defect in melanosomal transfer. Canities is an aging sign which often interferes with one’s socio‐cultural adjustment. On the other hand, premature canities correlate with diseases such as osteopenia and cardiovascular disease. Risk factors associated with canities are not only genetic but also external causes. For example, smoking, alcohol consumption, and stress are among the most common factors. Camouflage techniques are still used as the primary treatment of canities. Further treatments for canities are being developed to achieve the true reversal of hair pigmentation.


Aging of the Hair Follicle Pigmentation System

Skin and hair phenotypes are powerful cues in human communication. They impart much information, not least about our racial, ethnic, health, gender and age status. In the case of the latter parameter, we experience significant change in pigmentation in our journey from birth to puberty and through to young adulthood, middle age and beyond. The hair follicle pigmentary unit is perhaps one of our most visible, accessible and potent aging sensors, with marked dilution of pigment intensity occurring long before even subtle changes are seen in the epidermis. This dichotomy is of interest as both skin compartments contain melanocyte subpopulations of similar embryologic (i.e., neural crest) origin. Research groups are actively pursuing the study of the differential aging of melanocytes in the hair bulb versus the epidermis and in particular are examining whether this is in part linked to the stringent coupling of follicular melanocytes to the hair growth cycle. Whether some follicular melanocyte subpopulations are affected, like epidermal melanocytes, by UV irradiation is not yet clear. A particular target of research into hair graying or canities is the nature of the melanocyte stem compartment and whether this is depleted due to reactive oxygen species-associated damage, coupled with an impaired antioxidant status, and a failure of melanocyte stem cell renewal. Over the last few years, we and others have developed advanced in vitro models and assay systems for isolated hair follicle melanocytes and for intact anagen hair follicle organ culture which may provide research tools to elucidate the regulatory mechanisms of hair follicle pigmentation. Long term, it may be feasible to develop strategies to modulate some of these aging-associated changes in the hair follicle that impinge particularly on the melanocyte populations.


Dihydrotestosterone-inducible IL-6 inhibits elongation of human hair shafts by suppressing matrix cell proliferation and promotes regression of hair follicles in mice.

Autocrine and paracrine factors are produced by balding dermal papilla (DP) cells following dihydrotestosterone (DHT)-driven alterations and are believed to be key factors involved in male pattern baldness. Herein we report that the IL-6 is upregulated in balding DP cells compared with non-balding DP cells. IL-6 was upregulated 3  hours after 10-100  nM DHT treatment, and ELISA showed that IL-6 was secreted from balding DP cells in response to DHT. IL-6 receptor (IL-6R) and glycoprotein 130 (gp130) were expressed in follicular keratinocytes, including matrix cells. Recombinant human IL-6 (rhIL-6) inhibited hair shaft elongation and suppressed proliferation of matrix cells in cultured human hair follicles. Moreover, rhIL-6 injection into the hypodermis of mice during anagen caused premature onset of catagen. Taken together, our data strongly suggest that DHT-inducible IL-6 inhibits hair growth as a paracrine mediator from the DP.


Cytokines and Other Mediators in Alopecia Areata

Alopecia areata, a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin, has been extensively studied as far as the role of several cytokines is concerned. So far, IFN-, interleukins, TNF-, are cytokines that are well known to play a major role in the pathogenesis of the disease, while several studies have shown that many more pathways exist. Among them, MIG, IP-10, BAFF, HLA antigens, MIG, as well as stress hormones are implicated in disease onset and activity. Within the scope of this paper, the authors attempt to shed light upon the complexity of alopecia areata underlying mechanisms and indicate pathways that may suggest future treatments.

 

INGREDIENTS:

 


 

 

Andrographis Paniculata

  1. Antioxidant and Anti-Inflammatory Activities of the Plant Andrographis Paniculata Nees
  2. Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-κB Transactivation Inhibition
  3. Inhibitory effect of andrographolidefrom Andrographis paniculata on PAF-induced platelet aggregation
  4. Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression
  5. Effect of an extract of Andrographis paniculata leaves on inflammatory and allergic mediators in vitro
  6. AP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata
  7. Antiangiogenic activity of Andrographis paniculata extract and andrographolide
  8. In vitro modulation of LPS/calcimycin induced inflammatory and allergic mediators by pure compounds of Andrographis paniculata(King of bitters) extract
  9. Inhibitory Effects of Ethyl Acetate Extract of Andrographis paniculata on NF-κB Trans-Activation Activity and LPS-Induced Acute Inflammation in Mice
  10. Andrograpanin, a compound isolated from anti‐inflammatorytraditional Chinese medicine Andrographis paniculata, enhances chemokine SDF‐1α‐induced leukocytes chemotaxis
  11. An in vitro study of anti-inflammatory activityof standardised Andrographis paniculata extractsand pure andrographolide
  12. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways
  13. Review on Liver Inflammation and Antiinflammatory Activity of Andrographis paniculata for Hepatoprotection
  14. Effect of noni (Morinda citrifolia ) and fahtalaijons (Andrographis paniculata) on pigmentation and phagocytosis in goldfish (Carasius auratus)
  15. 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment
  16. The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-κB pathway
  17. Antioxidant, antinociceptive and anti-inflammatory properties of the aqueous and ethanolic leaf extracts of Andrographis paniculata in some laboratory animals
  18. Green approach for synthesis of zinc oxide nanoparticles from Andrographis paniculata leaf extract and evaluation of their antioxidant, anti-diabetic, and anti-inflammatory activities
  19. Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
  20. Antioxidant and gastroprotective activities of Andrographis paniculata (Hempedu Bumi) in Sprague Dawley rats
  21. In Vitro Comparative Evaluation of Non-Leaves and Leaves Extracts of Andrographis paniculata on Modulation of Inflammatory Mediators
  22. Protective Effects of Andrographis paniculata Extract and Pure Andrographolide Against Chronic Stress-Triggered Pathologies in Rats
  23. Andrographis paniculata Downregulates Proinflammatory Cytokine Production and Augments Cell Mediated Immune Response in Metastatic Tumor-Bearing Mice
  24. Rapid extraction of andrographolide from Andrographis paniculataNees by three phase partitioning and determination of its antioxidant activity
  25. Andrographis paniculata(Burm. f.) Wall. ex Nees (kalmegh), a traditional hepatoprotective drug from India
  26. ANDROGRAPHIS PANICULATA AND ITS BIOACTIVE PHYTOCHEMICAL CONSTITUENTS FOR OXIDATIVE DAMAGE: A SYSTEMIC REVIEW
  27. Andrographolide, a major component of Andrographis paniculata leaves, has the neuroprotective effectson glutamate-induced HT22 cell death
  28. Study on the pharmacokinetics of Andrographis paniculata Nees’s anti-inflammatory effect
  29. Hepatoprotective Effect of the Aqueous Leaf Extract of Andrographis paniculataNees Against Carbon Tetrachloride – Induced Hepatotoxicity in Rats
  30. Water Fraction Of Sambiloto (Andrographis Paniculata Nees) Ethanol Extract Efficacy In Inducing The Number Of Macrophage, Neutrophil, And The Level Of TNF-α On Wistar Rats
  31. Pengaruh ekstrak air herba sambiloto (andrographis paniculata) dan daun salam (syzygium polyanthum) terhadap jumlah tnf-α, makrofag dan neutrofil pada tikus yang diinduksi aloksan
  32. Effect of Andrographis Paniculata to the Expression of IL-6, IL-17, IL-10, TGFß, and the Ratio of Treg
  33. Effect of Andrographis Paniculata to the Expression of IL-6, IL-17, IL-10, TGFβ, and the Ratio of Treg/ Th17 in Sprague Dawley Rats with Atherosclerosis Diet an dCigarette Smoke

 

Anthocyanins ( From Blackberry Anthocyanin Extract )
  1. Application of Anthocyanins from Blackcurrant (Ribes nigrum L.) Fruit Waste as Renewable Hair Dyes
  2. Investigation on the dyeing power of some organic natural compounds for a green approach to hair dyeing
  3. Tart cherry anthocyanins suppress inflammation-induced pain behavior in rat
  4. Protective Effects of Anthocyanins from Blackberry in a Rat Model of Acute Lung Inflammation
  5. Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells
  6. Intakes of Anthocyanins and Flavones Are Associated with Biomarkers of Insulin Resistance and Inflammation in Women
  7. Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study
  8. Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro
  9. Anthocyanins and proanthocyanidins from blueberry–blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate‐utilizing enzymes in vitro
  10. Purple corn anthocyanins dampened high-glucose-induced mesangial fibrosis and inflammation: possible renoprotective role in diabetic nephropathy
  11. Synergistic inhibition of interleukin-6 production in adipose stem cells by tart cherry anthocyanins and atorvastatin
  12. Flavan‐3‐ols, anthocyanins, and inflammation
  13. Non-anthocyanin phenolics in cherry (Prunus avium L.) modulate IL-6, liver lipids and expression of PPARδ and LXRs in obese diabetic (db/db) mice
  14. Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis
  15. Bilberry-Derived Anthocyanins Prevent IFN-γ-Induced Pro-Inflammatory Signalling and Cytokine Secretion in Human THP-1 Monocytic Cells
  16. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress
  17. The role of anthocyanins as an antioxidant under oxidative stress in rats
  18. Anthocyanins Induce the Activation of Phase II Enzymes through the Antioxidant Response Element Pathway against Oxidative Stress-Induced Apoptosis
  19. Strawberry and Its Anthocyanins Reduce Oxidative Stress-Induced Apoptosis in PC12 Cells
  20. Preventive Effects of Dietary Cabbage Acylated Anthocyanins on Paraquat-induced Oxidative Stress in Rats
  21. Anthocyanins from Chinese Bayberry Extract Protect β Cells from Oxidative Stress-Mediated Injury via HO-1 Upregulation
  22. Effects of Anthocyanins on Psychological Stress-Induced Oxidative Stress and Neurotransmitter Status
  23. Anthocyanins Reversed D-Galactose-Induced Oxidative Stress and Neuroinflammation Mediated Cognitive Impairment in Adult Rats
  24. Cranberry anthocyanin extract prolongs lifespan of fruit flies
  25. Dietary Anthocyanins against Obesity and Inflammation
  26. Effects of blueberry anthocyanins on retinal oxidative stress and inflammation in diabetes through Nrf2/HO-1 signaling
  27. Anthocyanins from black soybean inhibit Helicobacter pylori‐induced inflammation in human gastric epithelial AGS cells
  28. Inhibition of low-grade inflammation by anthocyanins from grape extract in an in vitro epithelial-endothelial co-culture model
  29. Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells
  30. Purple carrot anthocyaninssuppress lipopolysaccharide-induced inflammation in the co-culture of intestinal Caco-2 and macrophage RAW264.7 cells
  31. Blueberry anthocyanins ameliorate cyclophosphamide-induced liver damage in rats by reducing inflammation and apoptosis
  32. Anthocyanins and their physiologically relevant metabolites alter the expression of IL‐6 and VCAM‐1 in CD40L and oxidized LDL challenged vascular endothelial cells
  33. AnthocyaninExtracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-κB
Apigenin ( From
  1. Inhibitory Effect of Apigenin, a Plant Flavonoid, on Epidermal Ornithine Decarboxylase and Skin TumorPromotion in Mice
  2. Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid.
  3. Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes
  4. Skin anti-inflammatory activity of apigenin-7-glucoside in rats.
  5. Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation
  6. Src kinase is a direct target of apigenin against UVB-induced skin inflammation
  7. Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications
  8. In Vivo and In Vitro Percutaneous Absorption of Cancer Preventive Flavonoid Apigenin in Different Vehicles in Mouse Skin
  9. Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skincancer prevention
  10. Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling cascades
  11. Dietary apigenin attenuates the development of atopic dermatitis-like skin lesions in NC/Nga mice
  12. Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro
  13. Influence of Vehicle, Distant Topical Delivery, and Biotransformation on the Chemopreventive Activity of Apigenin, a Plant Flavonoid, in Mouse Skin
  14. Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
  15. Anti-Inflammatory Effects of Apigenin in Lipopolysaccharide-Induced Inflammatory in Acute Lung Injury by Suppressing COX-2 and NF-kB Pathway
  16. Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages
  17. Anti-inflammatory mechanisms of apigenin: inhibition of cyclooxygenase-2 expression, adhesion of monocytes to human umbilical vein endothelial cells, and expression of cellular adhesion molecules
  18. Apigenin inhibits allergen-induced airway inflammation and switches immune response in a murine model of asthma
  19. Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium
  20. Apigenin inhibits release of inflammatory mediators by blocking the NF-κB activation pathways in the HMC-1 cells
  21. Apigenin Blocks Lipopolysaccharide-Induced Lethality In Vivo and ProinflammatoryCytokines Expression by Inactivating NF-κB through the Suppression of p65 Phosphorylation
  22. Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 (ginseng) and parthenolide (feverfew)
  23. Dietary Apigenin Suppresses IgE and Inflammatory Cytokines Production in C57BL/6N Mice
  24. Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells
  25. Apigenin Attenuates Experimental Autoimmune Myocarditis by Modulating Th1/Th2 Cytokine Balance in Mice
  26. Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects
  27. Apigenin protects endothelium-dependent relaxation of rat aorta against oxidative stress
  28. Apigenin inhibits oxidative stress‐induced macromolecular damage in N‐nitrosodiethylamine (NDEA)‐induced hepatocellular carcinogenesis in Wistar albino rats
  29. Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells
  30. Exposure of breast cancer cells to a subcytotoxic dose of apigenin causes growth inhibition, oxidative stress, and hypophosphorylation of Akt
  31. Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells
  32. Apigenin protects ovalbumin-induced asthma through the regulation of Th17 cells
  33. The IL-23/IL-17 axis in inflammation
  34. Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP-1 and NF-κB Signaling in Human Bladder Cancer T24 Cells
  35. Inhibitory effect of apigenin on nitric oxide production in chondrocytes induced by IL-1 and LPS
  36. Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells
  37. Apigenin Inhibits the Expression of IL-6, IL-8, and ICAM-1 in DEHP-Stimulated Human Umbilical Vein Endothelial Cells and In Vivo
  38. Apige nin inh ib its indoxyl sul fate-inducedend opla smic reti culum stress andan ti -pro lif era tive pat hways, CHOP and IL -6/p 21, in hu man renal proxim al t ubu lar c
  39. Antitumor and Anti-Invasive Effect of Apigenin on Human Breast Carcinoma through Suppression of IL-6 Expression
  40. Sa1794 Apigenin Attenuates Cerulein-Induced Parathyroid Hormone-Related Protein (PTHrP) and IL-6 in a Model of Murine Pancreatitis
  41. 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-α-mediated apoptosis
  42. Effect of apigenin, kaempferol and resveratrol on the gene expression and protein secretion of tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) in RAW-264.7 macrophages
  43. Apigenin prevents TNF-α induced apoptosis of primary rat retinal ganglion cells.
  44. Differential response to apigenin in African American triple-negative breast cancer in reducing TNF-α mediated rise in CXCL1
  45. Apigenin Exerts Anti-inflammatory Effects in an Experimental Model of Acute Pancreatitis by Down-regulating TNF-α
Arctigenin (from Fructus Arctii)
  1. Cosmetic composition for skin whitening comprising arctiin, arctigenin or the mixture thereof as active
  2. Anti-aging agent containing arctigenin derivative
  3. Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway
  4. Arctigenin Suppress Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis Through AMPK and PPAR-γ/ROR-γt Signaling
  5. Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17differentiation
  6. Arctigenin attenuates imiquimod-induced psoriasis-like skin lesions via down-regulating keratin17
  7. Arctigenin regulates Th1 and Th17differentiation and ameliorates experimental autoimmune encephalomyelitis (THER7P.958)
  8. Arctigenin improves vascular tone and decreases inflammation in human saphenous vein
  9. Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway
  10. Arctigenin , a phenylpropanoid dibenzylbutyrolactone lignan, inhibits type I–IV allergic inflammation and pro-inflammatory enzymes
  11. Arctigenin Treatment Protects against Brain Damage through an Anti-Inflammatory and Anti-Apoptotic Mechanism after Needle Insertion
  12. Arctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, HO-1, and iNOS Signaling
  13. Anti-inflammatory activity of arctigenin from Forsythiae Fructus
  14. Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
  15. Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonicinflammatory response induced by dextran sulfate sodium in mice
  16. Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes
  17. Arctigenin improves vascular tone and decreases inflammation in human saphenous vein
  18. Anti-inflammatory activity of arctigenin from Forsythiae Fructus
  19. In vitro anti-inflammatory effects of arctigenin , a lignan from Arctium lappa L., through inhibition on iNOS pathway
  20. Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
  21. Arctigenin , a phenylpropanoid dibenzylbutyrolactone lignan, inhibits type I–IV allergic inflammation and pro-inflammatory enzymes
  22. Arctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, HO-1, and iNOS Signaling
  23. Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation
  24. Arctigenin , a Natural Lignan Compound, Induces Apoptotic Death of Hepatocellular Carcinoma Cells via Suppression of PI3‐K/Akt Signaling
  25. β-Catenin Mediates Anti-adipogenic and Anticancer Effects of arctigenin in Preadipocytes and Breast Cancer Cells
  26. Protective Effects of arctigenin and Arctiin in H_2O_2-Treated SHSY_5Y Cells
  27. Arctigenin suppresses inflammation and plays a neuroprotective effect in mice with spinal cord injury
  28. Arctigenin exerts protective effects against myocardial infarction via regulation of iNOS, COX‑2, ERK1/2 and HO‑1in rats
  29. Arctigenin Ameliorates Inflammation by Regulating Accumulation and Functional Activity of MDSCs in Endotoxin Shock
  30. Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

 


Asiasari Radix

  1. The hair growth promoting effect of Asiasari radix extract and its molecular regulation
  2. KESHARAJA: HAIR VITALIZING HERBS
  3. Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors
  4. Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn) Mice
  5. Hair Growth: Focus on Herbal Therapeutic Agent
  6. Plants used for hair growth promotion:A review
  7. Regulatory Effect of Inflammatory Reaction of Asiasari Radix
  8. Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
  9. Hair Loss and the Applied Techniques for Identification of Novel Hair Growth Promoters for Hair Re-Growth
  10. Medical Treatment of Hair Loss
  11. Hair Growth-Promoting Effects in C57BL/6 Mice
  12. Anti-oxidation and Anti-inflammatory Effect of Asiasari Radix in RAW 264.7 Cells
  13. Partially purified Asiasari radix inhibits melanogenesisthrough extracellular signal-regulated kinase signaling in B16F10 cells
  14. Effect of Aqueous Extract from Asiasari Radixon α
    -melanocyte Stimulating Hormone Induced Melanogenesis in B16F10 Melanoma Cells
  15. Study on Advances of Medicine and Its Active Ingredient on the Hair Follicle of Different Animals
  16. Studies on Antitussive Principles of Asiasari Radix
  17. Effects of Asiasari radix on the morphology and viability of mesenchymal stem cells derived from the gingiva
  18. Protection of brain cells against AMPA‐induced damage by Asiasari radix extracts
  19. Study of components in crude drugs by head space gas chromatography. I. Components of Asiasari radix
  20. Composition containing Asiasari Radix extractsfor protecting brain cells and improving memory
  21. Studies of Inhibitory Mechanism on Melanogenesis by Partially Purified Asiasari radixin α-MSH Stimulated B16F10 Melanoma Cells
  22. Asiasari radix was demonstrated to stimulate hair growth in C57BL/6 and C3H mice by increasing the proliferation of HaCaT and human dermal papilla cells (DPCs) and inducing the expression of VEGF in human DPCs
  23. Studies of Inhibitory Mechanism on Melanogenesis by Partially Purified Asiasari radix in α-MSH
  24. Isolation of Five Compounds from Asiasari Radix
  25. Effects of aqueous extracts from Asiasari Radix on α-melnocyte stimulating hormone induced melanogenesis in B16F10 mouse melanoma cell
  26. Alternative Medicine for Hair Loss
  27. Anticancer potential of an ethanol extract of Asiasari radixagainst HCT-116 human colon cancer cells in vitro
  28. Isolation of a cytotoxic agent from Asiasari Radix
  29. Insulin inhibits AMPA-induced neuronal damage via stimulation of protein kinase B (Akt)
  30. Immunopharmacological studies on the anti-allergic actions of traditional Chinese medicinesand related components

 

 

astilbin

  1. t-Flavanone Improves the Male Pattern of Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study
  2. Mechanism and effect of Shijueming (Concha Haliotidis) on serum calcium in spontaneously hypertensive rats

 


Astragali Radix

  1. Radix Astragali injection enhances recovery from acute acoustic trauma
  2. Inhibitory activities against testosterone 5α-reductase and its hair growth promotion activities
  3. Review of Astragali Radix
  4. New Isoflavonoid Glycosides and Related Constituents from Astragali Radix (Astragalus membranaceus) and Their Inhibitory Activity on Nitric Oxide Production
  5. Comparative analysis of multiple representative components in the herb pair Astragali Radix-Curcumae Rhizoma and its single herbs by UPLC-QQQ-MS
  6. Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
  7. Effects of Traditional Chinese Medicine Huangqi Injection (Radix astragali)on Random Skin Flap Survival in Rats
  8. Radix astragali injection enhances recovery from sudden deafness
  9. Herbal composition for the treatment of alopecia
  10. Hair growershaving actions of promoting proliferation of hair papilla cells
  11. The Effects of Shi-Quan-Dai-Bu-Tang and Its Ingredients on the Survival of Jejunal Crypt Cells and Hematopoietic Cells in Irradiated Mice
  12. Hair growth effectof traditional Chinese medicine BeauTop on androgenetic alopecia patients: A randomized double-blind placebo-controlled clinical trial
  13. Effect of Herbal Medicines Pharmacopuncture on Hair Growth,a Review of Animal Study Reports Published in Koreae
  14. Medical herb composition for promoting the growth of hairA mammal and the manufacturing method thereof
  15. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk
  16. Pro-inflammatory cytokine gene expression and nitric oxide regulation of aqueous extracted Astragali radix in RAW 264.7 macrophage cells
  17. Effect of Astragali Radix Extract on Lipopolysaccharide-Induced Inflammation in Human Amnion
  18. Synergistic interaction between Astragali Radix and Rehmanniae Radix in a Chinese herbal formula to promote diabetic wound healing
  19. Chinese medicinal herb Radix Astragalisuppresses cardiac contractile dysfunction and inflammation in a ratmodel of autoimmune myocarditis
  20. Protective effect of Astragali radix extract on interleukin 1β‐induced inflammation in human amnion
  21. Wound-healing activity of Astragali Radix in rats.
  22. Alleviation of osteoarthritis by calycosin-7-O-β-d-glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model
  23. Isolation of Hyaluronidase Inhibitory Component from the Roots of Astraglus membranaceus Bunge (Astragali Radix)
  24. Anti-atherosclerotic function of Astragali Radix extract:downregulation of adhesion molecules in vitro and in vivo
  25. Inhibitory Effect of Astragali Radix on Matrix Degradation in Human Articular Cartilage
  26. Phenolic Derivatives from Radix Astragaliand their Anti-inflammatory Activities
  27. Immune-enhancing effect of Danggwibohyeoltang, an extract from Astragali Radixand Angelicae gigantis Radix, in vitro and in vivo
  28. Immunomodulatory Effect of Astragali Radix Extract on Murine Th1/Th2 Cell Lineage Development
  29. Transcriptional profiling of human skin fibroblast cell lineHs27 induced by herbal formula Astragali Radixand Rehmanniae Radix
  30. Ethanolic Extract of Astragali Radix and Salviae Radix Prohibits Oxidative Brain Injury by Psycho-Emotional Stress in Whisker Removal Rat Model
  31. Effect on TNF-α,IL-1 and IL-6 of Viral Myocarditis Treated by Radix Astragali Injection
  32. Effects of Radix astragali inoculation fluid on serum TNF-α and ET-1 levels in patients with acute cerebral infarction and significance.
  33. The effects of Radix astragali on TNF-α, IL-6 in serum of infants with rotavirus enteritis
  34. Effect of Acupuncture and Radix Astragali aqua-acupuncture at Synsu(BL23) on transcriptional expression of mouse cytokine IL-6
Baicalin ( FROM Scutellaria Baicalensis Root Extract )
  1. Baicalin inhibits IL-17-mediated joint inflammation in murine adjuvant-induced arthritis
  2. Identification of Baicalin as an Immunoregulatory Compound by Controlling TH17 Cell Differentiation
  3. Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting the Th17 Response in C57BL/6 Mice
  4. Baicalin inhibits IgG production by regulating Treg/Th17 axis in a mouse model of red blood cell transfusion
  5. Identification of Baicalin as an Immunoregulatory Compound by Controlling TH17 Cell Differentiation
  6. Baicalin Attenuates IL-17-Mediated Acetaminophen-Induced Liver Injury in a Mouse Model
  7. Baicalin attenuates TNBS-induced colitis in rats by modulating the Th17/Treg paradigm
  8. Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting the Th17Response in C57BL/6 Mice
  9. Regulatory effect of Baicalin on the imbalance of Th17/Treg responses in mice with allergic asthma
  10. Study on the inhibitory activity, in vitro, of baicalein and Baicalin against skin fungi and bacteria
  11. Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis
  12. Baicalin modulates microRNA expression in UVB irradiated mouse skin
  13. Effect of low molecular weight chitosans on drug permeation through mouse skin: 1. Transdermal delivery of Baicalin
  14. Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, Baicalin , and vitamin e for treatment of mild to moderately photodamaged skin.
  15. The Effects of Baicalin Against UVA-Induced Photoaging in Skin Fibroblasts
  16. Protective effect of Baicalin against multiple ultraviolet b exposure-mediated injuries in C57BL/6 mouse skin
  17. Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways
  18. Effects of dietary Baicalin supplementation on iron overload-induced mouse liver oxidative injury
  19. The flavonoid Baicalin counteracts ischemic and oxidative insults to retinal cells and lipid peroxidation to brain membranes
  20. Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Aβ aggregation in SH-SY5Y cells
  21. Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis
  22. Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats
  23. Short-term feeding of Baicalin inhibits age-associated NF-κB activation
  24. Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation, oxidative stress and P38MAPK pathway in rat
  25. Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells
  26. Baicalin protects PC-12 cells from oxidative stress induced by hydrogen peroxide via anti-apoptotic effects
  27. Baicalin prevents cadmium induced hepatic cytotoxicity, oxidative stress and histomorphometric alterations
  28. Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat
  29. Protective Effects of Baicalin on Aβ1–42-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat
  30. The Protective Effect of Baicalin Against Lead-Induced Renal Oxidative Damage in Mice
  31. Study of the Effect of Baicalin and Its Natural Analogs on Neurons with Oxygen and Glucose Deprivation Involving Innate Immune Reaction of TLR2/TNF ?
  32. Baicalin Downregulates Porphyromonas gingivalis Lipopolysaccharide-Upregulated IL-6 and IL-8 Expression in Human Oral Keratinocytes by Negative Regulation of TLR Signaling
  33. Baicalin and Baicalein Inhibit Src Tyrosine Kinase and Production of IL-6
  34. Baicalin Ameliorates Dysimmunoregulation in Pristane-Induced Lupus Mice: Production of IL-6 and PGE2 and Activation of T cells
  35. Effects of baicalin on TNF-α, IL-6 and IL-10 in rats with severe acute pancreatitis.
  36. A Study of Baicalin Inhibiting the Activation of NF-kB and Synthesise of IL-6 in Systemic Inflammatory Response Syndrome
  37. Inhibitory effects of baicalin on IL-1β- induced MMP-1/TIMP-1 and its stimulated effect on Collagen-I production in human periodontal ligament cells
  38. The anti‐inflammatory effect of baicalin on hypoxia/reoxygenation and TNF‐α induced injury in cultural rat cardiomyocytes
  39. Effects of Baicalin and Octreotide on the Serum TNF-α Level and Apoptosis in Multiple Organs of Rats with Severe Acute Pancreatitis
  40. Influence of baicalin on TNF-α mRNA, caspase-3 and P-selectin expression in pancreatic tissue of rats with severe acute pancreatitis
  41. Analysis of Influence of Baicalin Joint Resveratrol Retention Enema on the TNF-α, SIgA, IL-2, IFN-γ of Rats with Respiratory Syncytial Virus Infection
  42. Baicalin protects against TNF-α-induced injury by down-regulating miR-191a that targets the tight junction protein ZO-1 in IEC-6 cells
  43. Effects of Baicalin on Apoptosis of Early Chorionic Trophoblast Cell Cultures Induced by Exosomatic TNF-α
  44. Effects of Baicalin on the expression of TNF-α, IL-1β in cerebraltissue after local cerebral ischemia-reperfusion in rats / 黄芩苷对大鼠缺血再灌注脑组织TNF-α、IL-1β表达的影响
  45. Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection
  46. Baicalin inhibitednuclear factor κB (NF-κB) activation and attenuatedsodium taurocholate of induced experimental pancreatitis in rats
Brazilian propolis extract powder
  1. Suppression of interleukin 17production by Brazilian propolis in mice with collagen-induced arthritis
  2. Brazilian propolis inhibits the differentiation of Th17 cells by inhibition of interleukin-6-induced phosphorylation of signal transducer and activator of transcription 3
  3. Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide andIL-6
  4. Brazilian propolis ameliorates trinitrobenzene sulfonic acid-induced colitis in mice by inhibiting Th1 differentiation
  5. Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity
  6. Antinociceptive and anti-inflammatory effects of Brazilian red propolis extract and formononetin in rodents
  7. Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
  8. Propolis effect on Th1/Th2 cytokines production by acutely stressed mice
  9. Nitric Oxide and Brazilian Propolis Combined Accelerates Tissue Repair by Modulating Cell Migration, Cytokine Production and Collagen Deposition in Experimental Leishmaniasis
  10. Stimulatory Effect of Brazilian Propolis on Hair Growth through Proliferation of Keratinocytes in Mice
  11. Brazilian green propolis improves immune function in aged mice
  12. Brazilian propolis protects Saccharomyces cerevisiae cells against oxidative stress
  13. Evaluation of the Potential of Brazilian Propolis against UV-Induced Oxidative Stress
  14. Green Brazilian propolis effects on sperm count and epididymis morphology and oxidative stress
  15. Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage
  16. Anti-Inflammatory and Antimicrobial Evaluation of Neovestitol and Vestitol Isolated from Brazilian Red Propolis
  17. Propolis: a review of its anti-inflammatory and healing actions
  18. Topical Brazilian propolis improves corneal wound healing and inflammation in rats following alkali burns
  19. Aqueous Extract of Brazilian Green Propolis: Primary Components, Evaluation of Inflammation and Wound Healing by Using Subcutaneous Implanted Sponges
  20. Chemical Composition and Anti-Inflammatory Effect of Ethanolic Extract of Brazilian Green Propolis on Activated J774A.1 Macrophages
  21. Propolis Induces Analgesic and Anti-inflammatory Effects in Mice and Inhibits In Vitro Contraction of Airway Smooth Muscle
  22. Brazilian green propolis modulates inflammation, angiogenesis and fibrogenesis in intraperitoneal implant in mice
  23. Propolis immunomodulatory action in vivo on Toll‐like receptors 2 and 4 expression and on pro‐inflammatory cytokines production in mice
  24. Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatoryresponse by blocking NF-κB and MAPK activation in macrophages
  25. Brazilian Red Propolis AttenuatesInflammatory Signaling Cascade in LPS-Activated Macrophages
  26. Molecular Mechanisms Underlying the In Vitro Anti-Inflammatory Effects of a Flavonoid-Rich Ethanol Extract from Chinese Propolis (Poplar Type)
  27. Chemical Characterization and Antioxidant, Antimicrobial, and Anti-Inflammatory Activities of South Brazilian Organic Propolis
  28. Chemical Constituents of Brazilian Propolis and Their Cytotoxic Activities
  29. Two Novel Cytotoxic Benzofuran Derivatives from Brazilian Propolis
  30. Correlation analysis between phenolic levels of Brazilian propolis extracts and their antimicrobial and antioxidant activities
  31. Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

 


Buxus Wallichiana Baill

  1. Histological and physico-chemical evaluation of Buxus wallichiana Baill.
  2. Evaluation of Hair Growth Activity of Buxus wallichianaBaill Extract in Rats
  3. Buxus wallichiana L., a multipurpose Himalayan tree in peril
  4. Preclinical studies of a novel polyherbal phyto–complex hair growth promoting cream
  5. Histological and physico-chemical evaluation of Buxus wallichiana Baill
  6. System and method for promoting hair growth and improving hair and scalp health
  7. Evaluation of antioxidant and antimicrobial activity of various extracts of Buxus wallichiana Baill wood
  8. PRELIMINARY ANTINFLAMMATORY STUDYOF DIFFERENT EXTRACTS OF BUXUS WALLICHIANA BAILL WOOD
  9. Powder microscopy and phytochemical screening on stem bark and leaves of Buxus wallichiana Baill – Buxaceae
  10. PROSPECT OF HERBS AS HAIR GROWTH POTENTIAL
Capparis spinosa L extract
  1. Capparis Spinosa L. promotes anti-inflammatory response in vitro through the control of cytokine gene expression in human peripheral blood mononuclear cells
  2. Anti-inflammatory potential of Capparis spinosa L. in vivo in mice through inhibition of cell infiltration and cytokine gene expression
  3. Anti-inflammatory Effects of Caper (Capparis spinosa L.) Fruit Aqueous Extract and the Isolation of Main Phytochemicals
  4. Capparis ovata treatment suppresses inflammatorycytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
  5. Evaluation of anti-bacterial activity of Capparis spinosa (Al-Kabara ) and Aloe vera extracts against Isolates Bacterial Skin Wound Infections in -vitro and in-vivo
  6. Isolation and identification of an anti-inflammatoryprinciple from Capparis spinosa.
  7. Biflavonoids from Caper (Capparis spinosa L.) Fruits and Their Effects in Inhibiting NF-kappa B Activation
  8. Effect of flavonoids rich extract of Capparis spinosa oninflammatory involved genes in amyloid-beta peptide injected rat model of Alzheimer’s disease
  9. Investigation for anti-inflammatory and anti-thrombotic activities of methanol extract of Capparis ovata buds and fruits
  10. Capparis spinosa protects against oxidative stress in systemic sclerosis dermal fibroblasts
  11. In vitro antioxidant and in vivo photoprotective effects of a lyophilized extract of Capparis spinosa L. buds
  12. Physiochemical and antioxidant responses of the perennial xerophyte Capparis ovata Desf. to drought
  13. Phenolic Compounds and Vitamin Antioxidants of Caper (Capparis spinosa)
  14. Effect of Tunisian Capparis spinosa L. extract on melanogenesis in B16 murine melanoma cells
  15. ROLES OF DURATION AND CONCENTRATION OF PRIMING AGENTS ON DORMANCY BREAKING AND GERMINATION OF CAPER (CAPPARIS SPINOSA L.) FOR THE PROTECTION OF ARID DEGRADED AREAS
  16. Biflavonoids from Caper (Capparis spinosa L.) Fruits and Their Effects in Inhibiting NF-kappa B Activation
Carnosol ( FROM Rosemary Extract )
  1. Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis
  2. Inhibitory effect of Carnosol on UVB-induced inflammation via inhibition of STAT3
  3. Inhibitory Effect of Carnosolon Phthalic Anhydride-Induced Atopic Dermatitis via Inhibition of STAT3
  4. Carnosol Inhibits Pro-Inflammatory and Catabolic Mediators of Cartilage Breakdown in Human Osteoarthritic Chondrocytes and Mediates Cross-Talk between Subchondral Bone Osteoblasts and Chondrocytes
  5. Anti‐inflammatoryactivity of rosemary extracts obtained by supercritical carbon dioxide enriched in carnosic acid and carnosol
  6. Carnosol protects against renal ischemia-reperfusion injury in rats
  7. Carnosol: A promising anti-cancer and anti-inflammatory agent
  8. Inhibition by rosemary and carnosol of 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation
  9. Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-κB in mouse macrophages
  10. The Mechanisms of Carnosol in Chemoprevention of Ultraviolet B-Light-Induced Non-Melanoma Skin Cancer Formation
  11. Syk/Src Pathway-Targeted Inhibition of Skin InflammatoryResponses by Carnosic Acid
  12. Carnosol and Related Substances Modulate Chemokine and Cytokine Production in Macrophages and Chondrocytes
  13. Carnosol inhibits cell adhesion molecules and chemokine expression by tumor necrosis factor-α in human umbilical vein endothelial cells through the nuclear factor-κB and mitogen-activated protein kinase pathways
  14. Carnosic acid reduces cytokine-induced adhesion molecules expression and monocyte adhesion to endothelial cells
  15. In vitro and in vivo anti-inflammatory effects of rosmanol and carnosol isolated from rosemary
  16. Carnosol promotes endothelial differentiation under H2O2-induced oxidative stress
  17. Anti‐inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions
  18. The Role of Nitric Oxide Synthase and Carnosol in UVB-induced NF-κB Activity and Skin Damage
  19. Protective effects of carnosol against oxidative stress induced brain damage by chronic stress in rats
  20. Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival

 

Ceratonia Siliqua Pod
  1. Phenolic acid content and free radical-scavenging activity of two differently processed carob tree (Ceratonia siliqua L.) pod
  2. Structure and Development of Stomata on the Primary Root of Ceratonia siliqua L.
  3. Reduction of hair growth
  4. Protective effects of polyphenol-rich infusions from carob (Ceratonia siliqua) leaves and cladodes of Opuntia ficus-indica against inflammation associated with diet-induced obesity and DSS-induced colitis in Swiss mice
  5. Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity
  6. Extract from Ceratonia siliqua Exhibits Depigmentation Properties
  7. Anti-inflammatory and antioxidant effect of Ceratonia siliqua L. methanol barks extract
  8. Carob pods (Ceratonia siliqua L.)inhibit human neutrophils myeloperoxidase and in vitro ROS-scavenging activity
  9. Gastroprotective effect of carob (Ceratonia siliqua L.)against ethanol-induced oxidative stress in rat
  10. The Study of Antibacterial Activity of Plantago Major and Ceratonia Siliqua
  11. Anti-Inflammatory Activity of Natural Products
  12. Protective Effect of Ceratonia siliqua L. Against a Dextran Sulfate Sodium-Induced Alterations in Liver and Kidney in Rat
  13. In vitro antioxidant and inhibitory activity of water decoctions of carob tree (Ceratonia siliqua L.) on cholinesterases, α-amylase and α-glucosidase
  14. Effects of extraction conditions on the recovery of phenolic compounds and in vitro antioxidant activity of carob (Ceratonia siliqua L.) pulp
  15. Characterization of bioactive compounds and ameliorative effects of Ceratonia siliqua leaf extract against CCl4 induced hepatic oxidative damageand renal failure in rats
  16. Ceratonia siliqua honeys from Morocco: Physicochemical properties, mineral contents, and antioxidant activities
  17. Ceratonia siliqua L. (immature carob bean) inhibits intestinal glucose absorption, improves glucose tolerance and protects against alloxan‐induced diabetes in rat
  18. Effects of aqueous extracts from Ceratonia siliqua L. pods on small intestinal motility in rats and jejunal permeability in mice
  19. Ceratonia siliqua pod extract ameliorates Schistosomamansoni-induced liver fibrosis and oxidative stress
  20. Bioactive metabolites involved in the antioxidant, anticancer and anticalpain activities of Ficus carica L., Ceratonia siliqua L. and Quercus ilex L. extracts


Chrysanthemum Zawadskii

  1. In vivo hair growth-stimulating effect of medicinal plant extract on BALB/c nude mice
  2. Chrysanthemum zawadskii extract induces hair growthby stimulating the proliferation and differentiation of hair matrix
  3. Phylogenetic analysis of Korean native Chrysanthemum species based on morphological characteristics
  4. Medicinal Plants for the Treatment of Hair Lossand the Suggested Mechanisms
  5. Hair growth promoting effect and action mechanism of Chrysanthemum zawadskii extract
  6. Hair restorer compositionusing oriental herbs
  7. Inhibitory Effects of Chromatographically Fractionated Extracts from Chrysanthemum zawadskii on Tyrosinase Activity and Melanogenesis
  8. The Functional Effects for the Prevention and Treatment on Hair Loss from Astringent Persimmon Fruit Extracts
  9. Growth and Morphological Characteristics of Wild Clones of Chrysanthemumboreale Mak
  10. Biological activities of the herb of Chrysanthemum zawadskii
  11. Inhibitors of Nitric Oxide in Raw 264.7 Macrophages treated with Linarin: The main compound of Chrysanthemum zawadskii
  12. Chrysanthemum zawadskii extract activates peroxisome proliferator-activated receptor-α and has an anti-inflammatory activity : Potential interest for the skin barrier function
  13. Immuno-Modulatory Activities of Polysaccharides separated from Chrysanthemum zawadskii var. latilobum in Macrophage Cells
  14. Effect of Chrysanthemum zawadskii and Menthaarvensis on skin barrier functionvia keratinocytes differentiation
  15. Abstract 5666: Nrf2-mediated induction of phase 2 detoxifying enzymes by an active compound isolated from Chrysanthemum zawadskii
  16. Chrysanthemum zawadskiivar. latilobum extract inhibits the production of nitric oxide and PGE2 through inducible nitric oxide synthase (iNOS) and cyclooxygenase-2(COX-2) in RAW 264. 7 cells
  17. Anti-inflammatory/Anti-oxidative Stress Activitiesand Differential Regulation of Nrf2-Mediated Genes by Non-Polar Fractions of Tea Chrysanthemum zawadskiiand Licorice Glycyrrhiza uralensis
  18. Anti-inflammatory activity of Chrysanthemum zawadskiivar. latilobum leaf extract through haem oxygenase-1 induction
  19. 6-Methoxyluteolin from Chrysanthemum zawadskii var.latilobum SuppressesHistamine Release and Calcium Influx via Down-Regulation of FcεRI αChain Expression
  20. Anti-inflammatory effectsof flavonoids in Korean Chrysanthemum speciesvia suppression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-induced RAW 264.7 macrophages
  21. Suppressive Effects of Chrysanthemum zawadskii var.latilobum Flower Extracts on Nitric Oxide Production and Inducible Nitric Oxide Synthase Expression
  22. Inhibitory Effects of 150 Plant Extracts on Elastase Activity, and Their Anti‐inflammatory Effects
  23. Isolation and identification of flavonoids from Gujeolcho (Chrysanthemum zawadskii var. latilobum) as inhibitor of histamine release
  24. A Study on Anti-oxidative, Anti-inflammatory,and Melanin Inhibitory Effects of Chrysanthemum Sibiricum Extract
  25. Articles : Analysis of Composition and Activity of Essential Oil from Chrysanthemum zawadskii var. Latilobum and C. indicum against Antibiotic-Resistant Pathogenic Bacteria
  26. Linarin down-regulates phagocytosis, pro-inflammatory cytokine production, and activation marker expression in RAW264.7 macrophages
  27. The Extract of Chrysanthemum zawadskiivar. latilobum Ameliorates Collagen-Induced Arthritis in Mice
  28. Chrysanthemum zawadskiiextract protects osteoblastic cells from highly reducing sugar-induced oxidative damage
  29. Identification of secondary metabolites with antioxidant and antimicrobial activities from Artemisia iwayomogi and Chrysanthemum zawadskii
  30. Extracts of Chrysanthemum zawadskii attenuate oxidative damage to vascular endothelial cells caused by a highly reducing sugar
  31. Chrysanthemum zawadskii var. latilobum Extracts Inhibits of TPA-induced Invasion by Reducing MMP-9 Expression Via the Suppression of NF-κB
    Activation in MCF-7 Human Breast Carcinoma Cells

 

cordycepin ( FROM Cordyceps Sinensis )
  1. The Effects of Cordycepin on Ovalbumin-Induced Allergic Inflammation by Strengthening Treg Response and Suppressing Th17 Responses in Ovalbumin-Sensitized Mice
  2. Cordycepin and a preparation from Cordyceps militaris inhibit malignant transformation and proliferation by decreasing EGFR and IL-17RA signaling in a murine oral cancer model
  3. Cordycepin Inhibits Differentiation of Th17 Cells and Promotes Generation of CD4+ CD25+ FoxP3+ Tregs In Vitro : 1100
  4. Cordycepin induces apoptosis in SGC‑7901 cells through mitochondrial extrinsic phosphorylation of PI3K/Akt by generating ROS
  5. Cordyceps sinensis may inhibit Th22 cell chemotaxis to improve kidney function in lgA nephropathy
  6. Effect of Cordycepinon the Expression of the Inflammatory CytokinesTNF-alpha, IL-6, and IL-17A in C57BL/6 Mice
  7. Cordycepin inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts
  8. Cordycepin prevented IL-β-induced expression of inflammatory mediators in human osteoarthritis chondrocytes
  9. Nucleotides. Part IL.† Synthesis and Characterization of Cordycepin‐Trimer‐Vitamin and ‐Lipid Conjugates Potential Inhibitors of HIV‐1 Replication
  10. Effect of CordycepinPurified from Cordyceps militaris on Th1 and Th2Cytokines in Mouse Splenocytes
  11. Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages
  12. A Phytochemically Characterized Extract of Cordyceps militaris and Cordycepin Protect Hippocampal Neurons from Ischemic Injury in Gerbils
  13. Role of Cordycepin and Adenosine on the Phenotypic Switch of Macrophages via Induced Anti-inflammatory Cytokines
  14. Cordycepin modulates inflammatory and catabolic gene expression in interleukin-1beta-induced human chondrocytes from advanced-stage osteoarthritis: an in vitro study
  15. Cordycepin-enriched Cordyceps militaris induces immunomodulation and tumor growth delay in mouse-derived breast cancer
  16. Regulation of human cytokines by Cordyceps militaris
  17. inflammatory disease: Potential implication for the selection of new therapeutic targets
  18. Cordycepin inhibits LPS-induced acute lung injury by inhibiting inflammation and oxidative stress
  19. Effect of Long-term Administration of Cordycepin from Cordyceps militaris on Testicular Function in Middle-aged Rats
  20. Cordycepin alleviates airway hyperreactivity in a murine model of asthma by attenuating the inflammatory process
  21. Anti-hepatocarcinoma effect of cordycepin against NDEA-induced hepatocellular carcinomas via the PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB pathway in mice
  22. Cordycepin diminishes thymic stromal lymphopoietin-induced interleukin-13 production
  23. Cordycepin Suppresses Thymic Stromal Lymphopoietin Expression via Blocking Caspase-1 and Receptor-Interacting Protein 2 Signaling Pathways in Mast Cells
  24. Cordycepin alleviates lipopolysaccharide-induced acute lung injury via Nrf2/HO-1 pathway
  25. Protective effects of cordycepin on the histopathological changes and oxidative stress induced by hepatic ischemia/reperfusion in rats
  26. Cordycepin inhibits LPS-induced inflammatory responses by modulating NOD-Like Receptor Protein 3 inflammasome activation
  27. Cordycepin (3′-deoxyadenosine) attenuates age-related oxidative stress and ameliorates antioxidant capacity in rats
  28. The neuroprotective effects of cordycepin inhibit glutamate-induced oxidative and ER stress-associated apoptosis in hippocampal HT22 cells
  29. Cordycepinprevents oxidative stress-induced inhibition of osteogenesis
  30. Polysaccharides from Cordyceps sinensis mycelium ameliorate exhaustive swimming exercise-induced oxidative stress
  31. Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination
  32. Cordycepin as a sensitizer to tumour necrosis factor (TNF)‐α‐induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)‐ and mammalian target of rapamycin complex 1 (mTORC1)‐mediated inhibition of nuclear factor (NF)‐κB
  33. Cordycepin protected against the TNF-α-induced inhibition of osteogenic differentiation of human adipose-derived mesenchymal stem cells
  34. Cordycepin inhibits vascular adhesion molecule expression in TNF‑α‑stimulated vascular muscle cells
  35. Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)-and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB
Cranberry peel extract
  1. Inhibition of interleukin‐17‐stimulated interleukin‐6 and ‐8 production by cranberry components in human gingival fibroblasts and epithelial cells
  2. Effects of cranberry components on IL-1β-stimulated production of IL-6, IL-8 and VEGF by human TMJ synovial fibroblasts
  3. Anti-Porphyromonas gingivalis and Anti-Inflammatory Activities of A-Type Cranberry Proanthocyanidins
  4. Cranberry Proanthocyanidins Improve Intestinal sIgA During Elemental Enteral Nutrition
  5. Cranberry components inhibit interleukin‐6, interleukin‐8, and prostaglandin E2 production by lipopolysaccharide‐activated gingival fibroblasts
  6. Effect of glycated albumin and cranberry components on interleukin‐6 and matrix metalloproteinase‐3 production by human gingival fibroblasts
  7. Cranberry extract suppresses interleukin-8 secretion from stomach cells stimulated by Helicobacter pylori in every clinically separated strain but inhibits growth in part of the strains
  8. Inhibition of interleukin 1β–stimulated interleukin‐6 production by cranberry components in human gingival epithelial cells: effects on nuclear factor κB and activator protein 1 activation pathways
  9. Comparison of Urinary Cytokines after Ingestion of Cranberry Juice Cocktail in Pregnant Subjects: A Pilot Study
  10. Anti-inflammatory Activity of a High-molecular-weight Cranberry Fraction on Macrophages Stimulated by Lipopolysaccharides from Periodontopathogens
  11. Effects of freeze-dried cranberry powder on serum lipids and inflammatory markers in lipopolysaccharide treated rats fed an atherogenic diet
  12. Effects of cranberry extracts and ursolic acid derivatives on P-fimbriated Escherichia coli, COX-2 activity, pro-inflammatory cytokine release and the NF-κβ transcriptional response in vitro
  13. Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts
  14. Effects of ginger and cranberry extracts on the physiological response to exercise and markers of inflammation in horses
  15. Prevention of oxidative stress, inflammationand mitochondrial dysfunction in the intestine by different cranberry phenolic fractions
  16. Diets enriched with cranberry beans alter the microbiota and mitigate colitis severity and associated inflammation
  17. Anti-inflammatory effects of cranberry juice in lipopolysaccharide (LPS)-stimulated RAW 264.7 murine macrophage cells.
  18. Cranberry extract attenuates hepatic inflammation in high-fat-fed obese mice
  19. Effects of cranberry (Vaccinum macrocarpon) supplementation on iron status and inflammatory markers in rowers
  20. Cytoprotective effect of Proanthocyanidin‐rich cranberry fraction against bacterial cell wall‐mediated toxicity in macrophages and epithelial cells
  21. Cranberry Extract Modulate Inflammation In Irradiated Rats.
  22. Chapter 81 – Cranberry Polyphenols: Effects on Cardiovascular Risk Factors
  23. Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice
  24. Cranberry extract inhibits low density lipoprotein oxidation
  25. Reduced-energy cranberry juice increases folic acid and adiponectin and reduces homocysteine and oxidative stress in patients with the metabolic syndrome
  26. Low-energy cranberry juice decreases lipid oxidation and increases plasma antioxidant capacity in women with metabolic syndrome
  27. A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice
  28. Biological Activity of Cranberry Proanthocyanidins: Effects on Oxidation, Microbial Adhesion, Inflammation, and Health
  29. Effects of cranberry powder on serum lipid profiles and biomarkers of oxidative stress in rats fed an atherogenic diet
  30. Effects of cranberry powder on biomarkers of oxidative stress and glucose control in db/db mice
  31. CRANBERRY POLYPHENOLS DOWN-REGULATE THE TOLL-LIKE RECEPTOR 4 PATHWAY AND NUCLEAR FACTOR-KAPPA B ACTIVATION, WHILE STILL ENHANCING TUMOR NECROSIS FACTOR ΑLPHA SECRETION IN HL-60 CELLS
Curcumin ( From Turmeric root Extract )
  1. Curcumin, an antioxidant and anti-inflammatoryagent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
  2. Curcumin, inflammation, ageing and age-related diseases
  3. Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?
  4. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation.
  5. Effects of curcumin on retinal oxidative stress and inflammation in diabetes
  6. Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions
  7. Dietary Curcumin Significantly Improves Obesity-Associated Inflammation and Diabetes in Mouse Models of Diabesity
  8. Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice
  9. Curcumin Attenuates Acute Graft-versus-Host Disease Severity via In Vivo Regulations on Th1, Th17 and Regulatory T Cells
  10. Treatment of low doses curcumin could modulate Th17/Treg balance specifically on CD4+ T cell cultures of systemic lupus erythematosus patients
  11. Curcumin inhibiting Th17 cell differentiation by regulating the metabotropic glutamate receptor-4 expression on dendritic cells
  12. Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17production
  13. Curcumin protects against acute liver damage in the rat by inhibiting NF-κB, proinflammatory cytokines production and oxidative stress
  14. Curcumin downregulates the inflammatorycytokines CXCL1 and -2 in breast cancer cells via NFκB
  15. Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy
  16. Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokinesCXCL1 and -2
  17. Inhibition of NFκB Activation with Curcumin Attenuates Plasma InflammatoryCytokines Surge and Cardiomyocytic Apoptosis Following Cardiac Ischemia/Reperfusion1
  18. Investigation of the Effects of Curcumin on Serum Cytokines in Obese Individuals: A Randomized Controlled Trial
  19. Curcumin attenuates the release of pro‐inflammatory cytokines in lipopolysaccharide‐stimulated BV2 microglia
  20. Differential Regulation of Cytokines and Transcription Factors in Liver by Curcumin Following Hemorrhage/Resuscitation
  21. Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production
  22. [Effect of curcumin on IL-17-induced nitric oxide production and expression of iNOS in human keratinocytes].
  23. Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin
  24. Inhibition of interleukin 17 production by curcumin in mice with collagen-induced arthritis
  25. Curcumin ameliorates arterial dysfunction and oxidative stress with aging
  26. Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster
  27. Curcumin and aging
  28. Dietary Curcumin Ameliorates Aging-RelatedCerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway
  29. Curcumin induces heme oxygenase‐1 in normal human skin fibroblasts through redox signaling: Relevance for anti‐aging intervention
  30. Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
  31. Curcumin attenuates the expression of IL-1β, IL-6, and TNF-α as well as cyclin E in TNF-α-treated HaCaT cells; NF-κB and MAPKs as potential upstream targets
  32. Curcumin Attenuates Inflammatory Responses of TNF-α-Stimulated Human Endothelial Cells
  33. Curcumin Supplementation Lowers TNF-α, IL-6, IL-8, and MCP-1 Secretion in High Glucose-Treated Cultured Monocytes and Blood Levels of TNF-α, IL-6, MCP-1, Glucose, and Glycosylated Hemoglobin in Diabetic Rats
  34. The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids
  35. Curcumin Attenuates Diabetic Neuropathic Pain by Downregulating TNF-α in a Rat Model
  36. Effects of TNF-α and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells
  37. Curcumin ameliorates rabbits’s steatohepatitis via respiratory chain, oxidative stress, and TNF-α
  38. Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice
  39. Curcumin Attenuates TNF‐α‐induced Expression of Intercellular Adhesion Molecule‐1, Vascular Cell Adhesion Molecule‐1 and Proinflammatory Cytokines in Human Endometriotic Stromal Cells
  40. Anti-inflammatory potential of curcumin and quercetin in rats: Role of oxidative stress, heme oxygenase-1 and TNF-α
  41. Curcumin Blocks Interleukin-1 (IL-1) Signaling by Inhibiting the Recruitment of the IL-1 Receptor–Associated Kinase IRAK in Murine Thymoma EL-4 Cells
  42. Curcumin attenuates carcinogenesis by down regulating proinflammatory cytokine interleukin-1 (IL-1α and IL-1β) via modulation of AP-1 and NF-IL6 in lymphoma bearing mice
  43. Curcumin alleviates IL‐17A‐mediated p53‐PAI‐1 expression in bleomycin‐induced alveolar basal epithelial cells
  44. Curcumin attenuates IL-1β-induced endothelial lipase expression via blocking NF-κB pathway
  45. Curcumin Attenuates Expression of Adhesion Molecules by IL-1 β in HUVECs
  46. Inhibition of curcumin on the expression of IL-1 β-induced nuclear factor-κB-dependent inflammatory gene in rabbit RPE cells
  47. Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells
  48. Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice
  49. Curcumin, a Potential Inhibitor of Up-regulation of TNF-alpha and IL-6 Induced by Palmitate in 3T3-L1 Adipocytes through NF-kappaB and JNK Pathway
  50. Anti-ulcer Activity of Curcumin on Experimental Gastric Ulcer in Rats and Its Effect on Oxidative Stress/Antioxidant, IL-6 and Enzyme Activities
  51. Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-κB
  52. Curcumin Attenuates CFA Induced Thermal Hyperalgesia by Modulation of Antioxidant Enzymes and Down Regulation of TNF-α, IL-1β and IL-6
  53. [Reducing effect of curcumin on expressions of TNF-alpha, IL-6 and IL-8 in rats with chronic nonbacterial prostatitis].
  54. Inhibition of IL-6 Signaling Pathway by Curcumin in Uterine Decidual Cells
  55. TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats
  56. The Effect of Curcumin on TNF-α, IL-6 and CRP Expression in a Model of Polycystic Ovary Syndrome as an Inflammation State
  57. The functional protective effect and the mechanism of curcumin on IL-6 induced neuronal damage in rat hippocampus
  58. The polyphenols curcumin and resveratrol effectively block IL-1β and PMA-induced IL-6, IL-8 and VEGF-A expression in human rheumatoid synovial fibroblasts
  59. Effects of Curcumin on NF-κB、TNF-α and IL-6 in ALI/ARDS Rats Induced by Oleinic Acid
  60. Curcumin Suppression of IL-6 and IL-8 in Head & Neck Cancer: R115
  61. Curcumin, both Histone Deacetylase and p300/CBP‐Specific Inhibitor, Represses the Activity of Nuclear Factor Kappa B and Notch 1 in Raji Cells
  62. Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways
  63. Curcumin inhibits metastatic progression of breast cancer cell through suppression of urokinase-type plasminogen activator by NF-kappa B signaling pathways
  64. Curcumin Inhibits Cell Migration of Human Colon Cancer Colo 205 Cells through the Inhibition of Nuclear Factor kappa B /p65 and Down-regulates Cyclooxygenase-2 and Matrix Metalloproteinase-2 Expressions
  65. Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats
  66. Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition
  67. Hydrogel based oil encapsulation for controlled release of curcumin by using a ternary system of chitosan, kappa-carrageenan, and carboxymethylcellulose sodium salt
  68. Curcumin prevents shock-wave lithotripsy-induced renal injury through inhibition of nuclear factor kappa-B and inducible nitric oxide synthase activity in rats
  69. The effect of the NF-kappa B inhibitors curcumin and lactacystin on myogenic differentiation of rhabdomyosarcoma cells
  70. Curcumin attenuates IL-1β-induced endothelial lipase expression via blocking NF-κB pathway
  71. Response to “Inhibition of p300 and nuclear factor-[kappa]B by curcumin and its role in diabetic nephropathy”
  72. Curcumin inhibits mitogen stimulated lymphocyte proliferation, NF-kappa-B activation and IL-2 signaling
  73. Cerebroprotective role of Tetrahydro Curcumin in hyperhomocysteinemic ischemic mice by regulating NF-kappa B
  74. Combinatorial effect of curcumin and tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) in induction of apoptosis via inhibition of nuclear factor kappa activity and enhancement of caspase-3 activity in chronic myeloid cells: An In-vitro study
  75. Effect of curcumin on keloid fibroblasts cycle and nuclear factor-kappa B signaling pathways
Cyanidin ( FROm CornFlower Extract )
  1. The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo
  2. Cyanidin-3-O-β-glucoside attenuates allergic airway inflammation by modulating the IL-4Rα-STAT6 signaling pathway in a murine asthma model
  3. Anthocyanin-Rich Black Currant Extract and Cyanidin-3-O-Glucoside Have Cytoprotective and Anti-Inflammatory Properties
  4. Anti-inflammatory effects of black rice, cyanidin-3-O-β-d-glycoside, and its metabolites, cyanidin and protocatechuic acid
  5. Cyanidin-3-O-β-D-Glucopyranoside Concentrated Materials from Mulberry Fruit Have a Potency to Protect Erectile Function by Minimizing Oxidative Stress in a Rat Model of Diabetic Erectile Dysfunction
  6. Cyanidin-3-O-β-glucoside inhibits LPS-induced expression ofinflammatory mediators through decreasing IκBα phosphorylation in THP-1 cells
  7. Cyanidin-3-Glucoside Suppresses Cytokine-InducedInflammatoryResponse in Human Intestinal Cells: Comparison with 5-Aminosalicylic Acid
  8. Anti-inflammatory protection afforded by cyanidin-3-glucoside and resveratrol in human intestinal cells via Nrf2 and PPAR-γ: Comparison with 5-aminosalicylic acid
  9. Cyanidin-3-glucoside suppresses Th2 cytokinesand GATA-3 transcription factor in EL-4 T cells
  10. Cyanidin-3-O-β-glucoside inhibits lipopolysaccharide-inducedinflammatory response in mouse mastitis model
  11. Cyanidin-3-O-Glucoside Ameliorates Lipopolysaccharide-Induced Injury Both In Vivo and In Vitro Suppression of NF-κB and MAPK Pathways
  12. Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin
  13. Anti-aging Effectsof Cyanidin under a Stress-Induced Premature Senescence Cellular System
  14. Effects of Cyanidin-3-glycoside on PMA/Ionomycin-induced Th2 Cytokine Productions in RBL-2H3 Cells
  15. Inhibition of Carrageenan-Induced Acute Inflammation in Mice by Oral Administration of Anthocyanin Mixture from Wild Mulberry and Cyanidin-3-Glucoside
  16. [Antioxidant and anti-inflammatory effects of cyanidin from cherries on rat adjuvant-induced arthritis].
  17. Cyanidin-3-glucoside attenuates angiotensin II-induced oxidative stress and inflammation in vascular endothelial cells
  18. Synergistic effect of atorvastatin and Cyanidin-3-glucoside on angiotensin II-induced inflammation in vascular smooth muscle cells
  19. Protective Effects of Cyanidin‐3‐O‐β‐glucopyranoside Against UVA‐induced Oxidative Stress in Human Keratinocytes
  20. Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells
  21. Dietary cyanidin 3‐O‐β‐d‐glucoside increases ex vivo oxidation resistance of serum in rats
  22. Cyanidin-3-glucoside isolated from mulberry fruit protects pancreatic β-cells against oxidative stress-induced apoptosis
  23. Synergistic Effect of Cyanidin and PPAR Agonist against Nonalcoholic Steatohepatitis-Mediated Oxidative Stress-Induced Cytotoxicity through MAPK and Nrf2 Transduction Pathways
  24. Effect of cyanidin 3-O-β-glucopyranoside on hepatic stellate cell proliferation and collagen synthesis induced by oxidative stress
  25. Oxidation products of cyanidin 3‐O‐β‐d‐glucoside with a free radical initiator
  26. Neuroprotective effects of cyanidin against Aβ-induced oxidative and ER stress in SK-N-SH cells
  27. Cyanidin-3-O-Glucoside Modulates the In VitroInflammatory Crosstalk between Intestinal Epithelial and Endothelial Cells
  28. Cyanidin and Cyanidin-3-O-β-D-glucoside Suppress the Inflammatory Responsesof Obese Adipose Tissue by Inhibiting the Release of Chemokines MCP-1 and MRP-2
  29. Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice
  30. Antioxidant and anti-inflammatory activities of cyanidin-3-glucoside and cyanidin-3-rutinoside in hydrogen peroxide and lipopolysaccharide treated RAW264.7 cells (830.23)
  31. Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-α-induced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation
  32. Cyanidin-3-O-glucoside Protection against TNF-α-Induced Endothelial Dysfunction: Involvement of Nuclear Factor-κB Signaling
  33. Cyanidin-3-O-glucoside inhibits NF-kB signalling in intestinal epithelial cells exposed to TNF-α and exerts protective effects via Nrf2 pathway activation
  34. Inhibitory effect of polyphenol cyanidin on TNF-α-induced apoptosis through multiple signaling pathways in endothelial cells
  35. Cyanidin-3-glucoside suppresses TNF-α-induced cell proliferation through the repression of Nox activator 1 in mouse vascular smooth muscle cells: involvement of the STAT3 signaling
  36. Cyanidin-3-glucoside Inhibits TNF-α-Induced Mouse Vascular Smooth Muscle Cells Proliferation through Suppression of STAT3 Activation
Cycloastragenol ( FROM Astragalus Root Extract )
  1. Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome
  2. Evaluation of a novel anti-aging topical formulation containing cycloastragenol, growth factors, peptides, and antioxidants.
  3. Biocatalysis of Cycloastragenol by Syncephalastrum racemosum and Alternaria alternata to Discover Anti‐Aging Derivatives
  4. Microbial transformation of the anti-aging agent cycloastragenol by Mucor racemosus
  5. Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling

DHEA ( FROM Dehydroepiandrosterone Powder )
  1. Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome
  2. Serum Dehydroepiandrosterone (DHEA) and DHEA Sulfate Are Negatively Correlated with Serum Interleukin-6 (IL-6), and DHEA Inhibits IL-6 Secretion from Mononuclear Cells in Man in Vitro: Possible Link between Endocrinosenescence and Immunosenescence
  3. Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty
  4. Plasma concentration of interleukin 6 (IL-6), and its relationship with circulating concentration of dehydroepiandrosterone sulfate (DHEA-S) in patients with chronic idiopathic urticaria
  5. Increased serum levels of dehydroepiandrosterone (DHEA) and interleukin-6 (IL-6) in women with mild to moderate Alzheimer’s disease
  6. Dehydroepiandrosterone suppresses interleukin 10synthesis in women with systemic lupus erythematosus
  7. Regulation of Murine Interleukin-10 Production by Dehydroepiandrosterone
  8. Activation of Immune Function by Dehydroepiandrosterone (DHEA) in Age-Advanced Men
  9. Adrenal Hormone Modulation of Type 1 and Type 2 Cytokine Production by Spleen Cells: Dexamethasone and Dehydroepiandrosterone Suppress Interleukin-2, Interleukin-4, and Interferon-γ Productionin Vitro
  10. Regulation of murine lymphokine production in vivo II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells
  11. Changes in Dehydroepiandrosterone (DHEA) and DHEA-Sulfate Plasma Levels during Experimental Endotoxinemia in Healthy Volunteers
  12. Biochemical changes in the cervical tissue of rabbit induced by interleukin-8, interleukin-1βdehydroepiandrosterone sulphate and prostaglandin E2: a comparative study
  13. Effect of dehydroepiandrosterone on lipopolysaccharide-induced interleukin-6 production in DH82 cultured canine macrophage cells
  14. DHEA-Slevels in hypopituitaric patients with severe GH deficiency are strongly reduced across lifespan.Comparison with IGF-I levels before and during rhGH replacement
  15. Effects of 2-deoxyglucose and dehydroepiandrosterone on intracellular NAD+ level, SIRT1 activity and replicative lifespan of human Hs68 cells
  16. Physiological Concentrations of DHEA in Human Hair
  17. Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles
  18. Metabolic alterations of DHEA and cholesterol sulphates in the hair of patients with acne measured by liquid chromatography–mass spectrometry
  19. Diurnal and Seasonal Cortisol, Testosterone, and DHEA Rhythms in Boys and Girls during Puberty
  20. Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women
  21. Cytokine Dysregulation and Increased Oxidation Is Prevented by Dehydroepiandrosterone in Mice Infected with Murine Leukemia Retrovirus
  22. Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatorycytokines in aging humans
  23. Modulation of Cytokine Production by Dehydroepiandrosterone (DHEA) Plus Melatonin (MLT) Supplementation of Old Mice
  24. The endotoxin-induced increase of cytokines is followed by anincrease of cortisol relative to dehydroepiandrosterone (DHEA) inhealthy male subjects
  25. The Effects of Dehydroepiandrosterone (DHEA) on In Vitro Spleen Cell Proliferation and Cytokine Production
  26. Altered Cortisol/DHEA Ratio in Tuberculosis Patients and its Relationship with Abnormalities in the Mycobacterial‐driven Cytokine Production by Peripheral Blood Mononuclear Cells
  27. Dehydroepiandrosterone may be one of the regulators of cytokine production in atopic dermatitis
  28. The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: Potential steroid-sparing role for DHEA
  29. Preliminary studies on the effect of dehydroepiandrosterone (DHEA) on both constitutive and phytohaemagglutinin (PHA)‐inducible IL‐6 and IL‐2 mRNA expression and cytokine production in human spleen mononuclear cell suspensions in vitro
  30. Role of androgens in dhea-induced rack1 expression and cytokinemodulation in monocytes
  31. Low cortisol, high DHEA, and high levels of stimulated TNF‐α, and IL‐6 in women with PTSD
  32. The influence of age and gender on serum dehydroepiandrosterone sulphate (DHEA-S), IL-6, IL-6 soluble receptor (IL-6 sR) and transforming growth factor beta 1 (TGF-β1) levels in normal healthy blood donors
  33. IL-6, DHEA and the ageing process
  34. Activity of Lymphocyte Subpopulations in Polymicrobial Sepsis and DHEA Treatment in IL-6 Knockout Mice
  35. Low levels of cortisol and sIgA, high levels of DHEA-S, and high stimulated levels of TNF-α and IL-6 in women with PTSD
  36. DHEA Can Inhibit the Proliferation of Myeloma Cells and the IL-6 Production of Bone Marrow Mononuclear Cells from the Myeloma Patients.
  37. DHEA MODULATES CYTOKINE EXPRESSION VIA IL-6 IN A MULTIPLE
  38. 7018 POSTER Evaluation of serum IL-6, DHEA and DHEAS levels in comparison with two conventional metastatic markers in melanoma
  39. Dehydroepiandrosterone (DHEA) inhibits IL-6 secretion from monocytes and peripheral blood mononuclear cells (PBL) in man
  40. DHEA-dependent and organ-specific regulation of TNF-α mRNA expression in a murine polymicrobial sepsis and trauma model
  41. Are alterations of lymphocyte subpopulations in polymicrobial sepsis and DHEA treatment mediated by the tumour necrosis factor (TNF)‐α receptor (TNF‐RI)? A study in TNF‐RI (TNF‐RI–/–) knock‐out rodents
  42. DHEA wirkt protektiv bei einer experimentellen polymikrobiellen Sepsis durch CLP — besteht eine pathogenetische Bedeutung des TNF-α?
  43. IL-6 vermittelt protektive Effekte des DHEA bei einer polymikrobiellen Sepsis
Dragon’s Blood from Croton lechleri
  1. In vitro antifungal activity of dragon’s blood from Croton urucurana against dermatophytes
  2. Observation of the Effect of Dragon’s Blood in Treating Moist Dermatitis Resulted from Radioactive Treatment of Nasopharyngeal Carcinoma
  3. Dragon’s Blood Inhibits ChronicInflammatory and Neuropathic Pain Responses by Blocking the Synthesis and Release of Substance P in Rats
  4. Effect of Resina Draconis on the Repair of SkinDefect Treated with Tissue Engineering Skin
  5. Dragon’s Blood ointment promoting acute skin wound healing in rat
  6. Effect of Sanguis draconis (a dragon’s blood resin) on streptozotocin- and cytokine-induced β-cell damage, in vitro and in vivo
  7. Sanguis draconis, a Dragon’s Blood Resin, Attenuates High Glucose-Induced Oxidative Stress and Endothelial Dysfunction in Human Umbilical Vein Endothelial
  8. Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis Draconis, a dragon’s blood resin, in RAW 264.7 cells
  9. Dragon’s blood and its extracts attenuate radiation-induced oxidative stress in mice
  10. Immunomodulatory Activity and Chemical Characterisation of Sangre de Drago (Dragon’s Blood)from Croton lechleri
  11. Ethylacetate extract from DraconisResinainhibits LPS-inducedinflammatory responses in vascular smooth muscle cells and macrophages via suppression of ROS production
  12. Mutagenic and antioxidant activities of Croton lechleri sap in biological systems
  13. Studies on anti-inflammation and analgesic effects of dragon’s blood
  14. Anti-inflammatory Flavan-3-ol-dihydroretrochalcones from Daemonorops draco
  15. Anti-Inflammatory And Analgesic Effects Of Ethanol Extract Of Dracaena Cinnabari Balf, As Endemic Plant In Yemen
  16. Dragon’s Blood May Have Radioprotective Effects in Radiation-Induced Rat Brain Injury
  17. Dragon’s blood dropping pills have protective effects on focal cerebral ischemia rats model
  18. Review of Sangre de Drago (Croton lechleri) – A South American Tree Sap in the Treatment of Diarrhea, Inflammation, Insect Bites, Viral Infections, and Wounds: Traditional Uses to Clinical Research
  19. Effects of Sangre de Drago from Croton lechleri Muell.-Arg. on the production of active oxygen radicals
  20. Inhibition of Neurogenic Inflammation by the Amazonian Herbal Medicine Sangre de Grado
  21. The Effect of ProstaglandinF_(2a) (PGF_(2a)) in the Blood Plasma and Interleukin-1?(IL-1?) in the Blood Serum of Endometriosis in the Rats Treated with Complex Prescription Dragon’s Blood Plaster


Eclipta Prostrata

  1. Antimicrobial activity and cytotoxicity of Eclipta prostrata
  2. Anti-inflammatory activity of methanolic extract of Eclipta prostrata L. (Astearaceae)
  3. Ethnopharmacological uses, phytochemistry, biological activities, and biotechnological applications of Eclipta prostrata
  4. Antidermatophytic activity of Eclipta prostrata L. against human infective Trichophyton and Microsporum spp.
  5. Three new olean-type triterpenoid saponins from aerial parts of Eclipta prostrata (L.)
  6. Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn
  7. Simultaneous extraction, identification and quantification of phenolic compounds in Eclipta prostrata using microwave-assisted extraction combined with HPLC–DAD–ESI–MS/MS
  8. Potent Antioxidativeand UVB Protective Effect of Water Extract of Eclipta prostrata L.
  9. Eclipta prostrata (L.) L. (Asteraceae)–an eco-friendly natural hair dye
  10. Use of Eclipta prostrataand other PPAR-gamma inhibitors in cosmeticsand compositions thereof
  11. IN VITROEVALUATION OF TOTAL PHENOLICS AND ANTIOXIDANT ACTIVITIES OF WITHANIA SOMNIFERA, ECLIPTA PROSTRATALAND GOSSYPIUM HERBASCEUML
  12. PHYTOCHEMICAL SCREENING AND ANTIOXIDANTPOTENTIAL OF ECLIPTA PROSTRATA (L) L-A VALUABLE HERB
  13. Selected PLants used as hair tonic
  14. Effects of Herbal Extracts on Hair Growthin an Animal Model of C3H/HeJ Mice
  15. In-Vitro Study of Anthelmintic Activity of Eclipta prostrata(L) y various Extracts
  16. Clinical Trials of Eclipta Prostrata (L.)L as Hepatoprotective and Their Market Formulations
  17. Echinocystic Acid Isolated from Eclipta prostrataSuppresses Lipopolysaccharide-Induced iNOS, TNF-α, and IL-6 Expressions via NF-κB Inactivation in RAW 264.7 Macrophages
  18. Osteoprotective Effect of Echinocystic Acid, a Triterpone Component from Eclipta prostrata, in Ovariectomy-Induced Osteoporotic Rats
  19. Ecliptamines A–D, four new guanidine alkaloids from Eclipta prostrata L.
  20. Eclipta prostrata Improves DSS-Induced Colitis through Regulation of Inflammatory Response in Intestinal Epithelial Cells
  21. Enhancement of Skin Anti-Inflammatory Activities of Eclipta prostrata L. from the Ultrasonic Extraction Process
  22. Effect of Eclipta prostrata on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
  23. The effects of Eclipta Prostrata L.(Ecliptae Herba) on periodontitis rats
  24. Wedelolactone from Vietnamese Eclipta prostrata (L) L. Protected Zymosan-induced shock in Mice
  25. A polysaccharide from Eclipta prostrata alleviates experimental autoimmune encephalomyelitis through inhibiting Th17 cells
  26. Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5
  27. Screening of antibacterial and antioxidant activities of leaves of Eclipta prostrata (L)
  28. Composition and method for stimulating the synthesis of the melanotic pigment of the skin
  29. Surfactant-assisted Water Extraction of Flavonoids from Eclipta Prostrata L.
  30. Primary Discussion on the Hemostatic Activity of Aqueous Extracts from the Leaves of Eclipta prostrata L.
Egcg ( From Green Tea Extract )
  1. EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control
  2. Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis
  3. Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFα
  4. Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signaling
  5. Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-inducedtumorigenic factors in U-2 OS human osteosarcoma cells
  6. EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells
  7. Green tea polyphenol (−)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-γ but not by IL-4
  8. (-)-Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 via Stat3 in gastric cancer
  9. ArticleEpigallocatechin-3-gallateamelioratesautoimmune arthritis by reciprocal regulationof T helper-17 regulatory T cells and inhibitionof osteoclastogenesis by inhibitingSTAT3 signaling
  10. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1β-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes
  11. Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic β-cell damage
  12. Novel chemotherapeutic and renal protective effects for the green tea (EGCG): Role of oxidative stressand inflammatory-cytokine signaling
  13. EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte
  14. The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells
  15. Effects of Varied EGCG and (+)-CatechinConcentrations on Proinflammatory Cytokines mRNA Expression in ConA-Stimulated Primary White Blood Cell Cultures
  16. Novel immunoregulatory properties of EGCG on reducing inflammation in EAE
  17. Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway
  18. Targeting of histamine producing cells by EGCG: a green dart against inflammation?
  19. Legionella pneumophila Replication in Macrophages Inhibited by Selective Immunomodulatory Effects on Cytokine Formation by Epigallocatechin Gallate, a Major Form of Tea Catechins
  20. Green Tea Polyphenol Epigallocatechin-3-gallate(EGCG) Differentially Inhibits Interleukin-1β-InducedExpression of Matrix Metalloproteinase-1 and -13 in Human Chondrocytes
  21. Epigallocatechin-3-O-gallate modulates global microRNA expression in interleukin-1β-stimulatedhuman osteoarthritis chondrocytes: potential role of EGCG on negative co-regulation of microRNA-140-3p and ADAMTS5
  22. Epigallocatechin-3-gallate inhibits angiotensin II and interleukin-6-induced C-reactive protein production in macrophages
  23. Stimulation of human monocyte and polymorphonuclear cell iodination and interleukin‐1production by epigallocatechin gallate
  24. Epigallocatechin-3-gallate inhibits interleukin-6-and angiotensin II-induced production of C-reactive protein in vascular smooth muscle cells
  25. (−)-Epigallocatechin-3-Gallate Prevents Photocarcinogenesis in Mice through Interleukin-12–Dependent DNA Repair
  26. Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes
  27. Regulation of interleukin‐1β–induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin‐3‐gallate in rheumatoid arthritis synovial fibroblasts
  28. Prevention of Ultraviolet Radiation–Induced Immunosuppression by (−)-Epigallocatechin-3-Gallatein Mice Is Mediated through Interleukin 12–DependentDNA Repair
  29. Epigallocatechin‐3‐gallate selectively inhibits interleukin‐1 β‐induced activation of mitogen activated protein kinase subgroup c‐Jun N‐terminal kinase in human osteoarthritis chondrocytes
  30. Epigallocatechin Gallate Attenuates Proliferation and Oxidative Stress in Human Vascular Smooth Muscle Cells Induced by Interleukin-1
    via Heme Oxygenase-1
  31. Regulation of Prostaglandin E2 (PGE2)-induced IL-6 production by Epigallocatechin-3-gallate (EGCG) in rheumatoid arthritis synovial fibroblasts
  32. Epigallocatechin-3-gallate (EGCG) inhibits IL-6-induced CRP synthesis and ameliorates adiponectin expression in Hep3B cells
  33. Chronic administration of low dose EGCG inhibits TNF-α-induced IL-6 and IL-8 production in rheumatoid arthritis synovial fibroblasts
  34. Epigallocatechin-3-gallate (EGCG) inhibits IL-1β-induced IL-6 production and cyclooxygenase-2 (COX-2) expression in rheumatoid arthritis synovial fibroblasts in vitro
  35. Effect of the green tea polyphenol epigallocatechin gallate (EGCG) on growth and IL-6 signalling pathways in malignant plasma cells
  36. 48th Annual Meeting of the Orthopaedic Research Society Poster No: 0423 EPIGALLOCATECHIN-3-GALLATE (EGCG) INHIBITS THE INFLAMMATORY EFFECTS OF IL-1BETA IN HUMAN CHONDROCYTES.
  37. Effects of EGCG from green tea on IL-1β -induced expression of MMP-1 and MMP-13, and production of PGE2 and NO on human IVD cells in vitro
  38. New TNF-α releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen
  39. EGCG stimulates the recruitment of brite adipocytes, suppresses adipogenesis and counteracts TNF-α-triggered insulin resistance in adipocytes
  40. EGCG attenuates the inhibitory effect of high TNF-α level on the process of wound healing in dermal fibroblasts
  41. The roles of caveolin-1 and heme oxygenase-1 in EGCG-mediated protection against TNF-α-induced endothelial inflammation
  42. Effects of Green Tea and EGCG on IL-8 Inflammatory Responses in LPS and TNF-α-Induced, Differentiated HT-29 Human Colon Cancer Cells
  43. INHIBITION OF TNF-α-INDUCED CASPASE-3 ACTIVITY BY EPIGALLOCATECHIN-3-GALLATE (EGCG) IN HUMAN ARTICULAR CHONDROCYTES.
ellagic acid ( FRom Pomegranate peel )
  1. Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn’s disease
  2. Ellagic acid alleviates adjuvant induced arthritis by modulation of pro- and anti-inflammatory cytokines
  3. Neuroprotective effects of ellagic acid on cuprizone-induced acute demyelination through limitation of microgliosis, adjustment of CXCL12/IL-17/IL-11 axisand restriction of mature oligodendrocytes apoptosis
  4. Ellagic acid reduces murine schistosomiasis mansoni immunopathology via up-regulation of IL-10 and down-modulation of pro-inflammatory cytokines production
  5. Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism
  6. Anti-inflammatory effects of Lafoensia pacari and ellagic acid in a murine model of asthma
  7. Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice
  8. Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells
  9. Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV‐B irradiation
  10. Anti-Inflammatory Effects of Ellagic Acidon Acute Lung Injury Induced by Acid in Mice
  11. The Modulatory Effect of Ellagic Acid and Rosmarinic Acid on Ultraviolet-B-Induced Cytokine/ChemokineGene Expression in Skin Keratinocyte (HaCaT) Cells
  12. Anti‐glycative and anti‐inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice
  13. Differential Inhibitory Effects of the Polyphenol Ellagic Acid on Inflammatory Mediators NF‐κB, iNOS, COX‐2, TNF‐α, and IL‐6 in 1,2‐Dimethylhydrazine‐Induced Rat Colon Carcinogenesis
  14. A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats
  15. Ellagic acidinhibits IL-1β-induced cell adhesion molecule expression in human umbilical vein endothelial cells
  16. Pharmacodynamics of ellagic acid on cardiac troponin-T, lyosomal enzymes and membrane bound ATPases: Mechanistic clues from biochemical, cytokine and in vitro studies
  17. Ellagic acid and polyphenolics present in walnut kernels inhibit in vitro human peripheral blood mononuclear cell proliferation and alter cytokineproduction
  18. Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum
  19. Molecular and biochemical evidence on the protective role of ellagic acid and silybin against oxidative stress-induced cellular aging
  20. NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts
  21. Inhibitory Effect of an Ellagic Acid-Rich Pomegranate Extract on Tyrosinase Activity and Ultraviolet-Induced Pigmentation
  22. Effects of Oral Administration of Ellagic Acid-Rich Pomegranate Extract on Ultraviolet-Induced Pigmentation in the Human Skin
  23. Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid
  24. Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid
  25. Ellagic Acid Prevents Cisplatin‐Induced Oxidative Stress in Liver and Heart Tissue of Rats
  26. Role of Ellagic Acid against Cisplatin‐Induced Nephrotoxicity and Oxidative Stress in Rats
  27. Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes
  28. Ellagic acid attenuates oxidative stress on brain and sciatic nerve and improves histopathology of brain in streptozotocin-induced diabetic rats
  29. The modulatory effects of ellagic acid and vitamin E succinate on TCDD‐induced oxidative stress in different brain regions of rats after subchronic exposure
  30. Ellagic acid ameliorates isoproterenol induced oxidative stress: Evidence from electrocardiological, biochemical and histological study
  31. Therapeutic effects of ellagic acid on memory, hippocampus electrophysiology deficits, and elevated TNF-α level in brain due to experimental traumatic brain injury
  32. ELLAGIC ACID IMPROVED COGNITIVE DEFICIT, BRAIN ELECTROPHYSIOLOGY DECAY AND BRAIN CONTENT OF TNF-α IN RAT WITH TRAUMATIC BRAIN INJURY
  33. Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism
  34. Ellagic acid protects against LPS-induced acute lung injury through inhibition of nuclear factor kappa B, proinflammatory cytokines and enhancement of interleukin-10
Emodin ( From Aloe VEra )
  1. [Effects of emodin on IL-23/IL-17 inflammatory axis, Th17 cells and viral replication in mice with viral myocarditis].
  2. Emodin inhibits splenocyte proliferation and inflammation by modulating cytokine responses in a mouse model system
  3. Emodin inhibited ozone stress-induced airway hyperresponsiveness by regulating epithelial protection mechanisms against injury
  4. Regulation of cell proliferation, inflammatorycytokineproduction and calcium mobilization in primary human T lymphocytes by emodinfrom Polygonum hypoleucum Ohwi
  5. Aloe-emodin prevents cytokine-induced tumor cell death: the inhibition of auto-toxic nitric oxide release as a potential mechanism
  6. Aloe-emodin Affects the Levels of Cytokines and Functions of Leukocytes from Sprague-Dawley Rats
  7. The influence of emodin and danshensu on monocyte^s secretion of inflammatorycytokines
  8. The Effects of Emodin on the Expression of Cytokines and Functions of Leukocytes from Sprague-Dawley Rats
  9. Aloe-emodin from rhubarb (Rheum rhabarbarum) inhibits lipopolysaccharide-inducedinflammatoryresponses in RAW264.7 macrophages
  10. Emodin Inhibits Proinflammatory Responses and Inactivates Histone Deacetylase 1 in Hypoxic Rheumatoid Synoviocytes
  11. Emodin suppresses inflammatory responses and joint destruction in collagen-induced arthritic mice
  12. Emodin inhibits LPS-inducedinflammatory response by activating PPAR-γ in mouse mammary epithelial cells
  13. Anti-Inflammatory Effect of Emodin via Attenuation of NLRP3 Inflammasome Activation
  14. Protective effect of emodin against airway inflammation in the ovalbumin-induced mouse model
  15. Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187
  16. Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X7 receptor
  17. Emodin ameliorates lipopolysaccharides-induced corneal inflammation in rats
  18. Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis
  19. The Molecular Effects of Aloe-Emodin(AE)/Liposome-AE on Human Nonmelanoma Skin Cancer Cells and Skin Permeation
  20. Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation–induced murine skin tumors
  21. Aloe-emodin inhibits proliferation of adult human keratinocytes in vitro
  22. Emodin suppresses interleukin-1β inducedmesangial cells proliferation and extracellular matrix production via inhibiting P38 MAPK
  23. [Interventional effects of emodin on transforming growth factor-beta1/integrin-linked kinase signal way in interleukin-1beta-induced transdifferentiation of rat tubular epithelial-myofibroblasts].
  24. Emodin mitigates diesel exhaust particles-induced increase in airway resistance, inflammation and oxidative stress in mice
  25. Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells
  26. Protective effects of emodin against cisplatin‐induced oxidative stress in cultured human kidney (HEK 293) cells
  27. Emodin-Provoked Oxidative Stress Induces Apoptosis in Human Colon Cancer HCT116 Cells through a p53-Mitochondrial Apoptotic Pathway
  28. Emodin, an anthraquinone derivative, protects against gamma radiation-induced toxicity by inhibiting DNA damage and oxidative stress
  29. Alteration of subcellular redox equilibrium and the consequent oxidative modification of nuclear factor κB are critical for anticancer cytotoxicity by emodin, a reactive oxygen species-producing agent
  30. Emodin Prevents Intrahepatic Fat Accumulation, Inflammation and Redox Status Imbalance During Diet-Induced Hepatosteatosis in Rats
  31. Effect of Emodin on Serum Albumin and TNF-α、IL-6 of Abdominal infection Rats
  32. Effect of Emodin on TNFα,IL-6 and Apoptosis of Pancreatic Acinar Cells in Severe Acute Pancreatitis in Rats
  33. Effect of emodin on secretion of TNF_?, IL-1, IL-6, and level of intracellular Ca~(2+) by rat peritoneal macrophage
  34. Original Article : Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-kB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187
  35. Emodin inhibits TNF α-induced MMP-1 expression through suppression of activator protein-1 (AP-1)
  36. Emodin inhibits TNF‐α‐induced human aortic smooth‐muscle cell proliferation via caspase‐ and mitochondrial‐dependent apoptosis
  37. Emodin attenuates TNF-α-induced apoptosis and autophagy in mouse C2C12 myoblasts though the phosphorylation of Akt
  38. Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway
  39. Research on changes of interleukin-1β and TNF- α in acute edematous pancreatitis and the intervention of emodin

 


Equisetum arvense

  1. Antinociceptive and anti-inflammatory propertiesof the hydroalcoholic extract of stems from Equisetum arvense L. in mice
  2. Equisetum arvense (common horsetail) modulates the function of inflammatory immunocompetent cells
  3. Phytochemistry and pharmacological propertiesof Equisetum arvenseL.
  4. Antioxidative and Antiproliferative Activities of Different Horsetail (Equisetum arvense L.) Extracts
  5. Chemical fingerprinting of Equisetum arvenseL. using HPTLC densitometry and HPLC
  6. The Effect of Equisetum Arvense (Horse Tail) Ointment on Wound Healing and Pain Intensity After Episiotomy: A Randomized Placebo-Controlled Trial
  7. Antioxidative activities of water extract and ethanol extract from field horsetail (tsukushi) Equisetum arvense L
  8. Urinary metabolites of flavonoidsand hydroxycinnamic acids in humans after application of a crude extract from Equisetum arvense
  9. Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats
  10. Growth in Vitro of Excised Roots of Equisetum arvense as Modified by Indole-3-Acetic, Indole-3-Butyric, and α-Naphthaleneacetic Acids
  11. Some Experiments on the Polarity of Spores in Dryopteris erthrosora and Equisetum arvense
  12. Occurrence of Dermatitis in Rats Fed a Cholesterol Diet Containing Field Horsetail (Equisetum arvense L.)
  13. Complete plastome sequences of Equisetum arvense and Isoetes flaccida: implications for phylogeny and plastid genome evolution of early land plant lineages
  14. Composition for treating hair and scalp and method for preparing same
  15. Cytological and proteomic analyses of horsetail (Equisetum arvense L.) spore germination
  16. Microwave-assisted extraction for the recovery of antioxidants from waste Equisetum arvense
  17. Silica deposition and ultrastructure in the cell wall of Equisetum arvense: the importance of cell wall structures and flow control in biosilicification?
  18. Equisetum arvense L. ExtractInduces Antibacterial Activity and Modulates Oxidative Stress, Inflammation, and Apoptosis in Endothelial Vascular Cells Exposed to Hyperosmotic Stress
  19. The Effects of Fermented Equisetum arvense on Moisturizing Capabilities in HaCaT Keratinocytes
  20. Physiological Activities of Extracts from Vegetative Stems of Equisetum arvense
  21. In Vitro Anti-inflammatory Effects of Equisetum arvenseAre Not Solely Mediated by Silica
  22. Composition and antimicrobial activity of Equisetum arvense L. essential oil
  23. Equisetum arvense hydromethanolic extracts in bone tissue regeneration: in vitro osteoblastic modulation and antibacterial activity
  24. Analysis of Phenolic Compounds Composition by HPLC andAssessment of Antioxidant Capacity in Equisetum arvense L. Extracts
  25. Evaluation of the efficacy of dietary supplements based on Equisetum arvense, Soy Isoflavones, Lactoferrin and vitamin D3 on the control of climacteric symptoms
  26. Radical scavenging and antimicrobial activity of horsetail (Equisetum arvense L.) extracts
  27. Consecutive Production of Hydroalcoholic Extracts, Carbohydrates Derivatives and Silica Nanoparticles from Equisetum arvense
  28. Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin
  29. The Saccharomyces cerevisiae transcriptome as a mirror of phytochemical variation in complex extracts of Equisetum arvense from America, China, Europe and India
  30. Study of acute hepatotoxicity of Equisetum arvense L. in rats
  31. Assessing the role of the transcription factor nuclear factor kappa B (NF-kB) in the anti-inflammatory activity of EQUISETUM ARVENSE (COMMON HORSETAIL) extracts

 

Ferulic acid ( From Rice Bran )
  1. Ferulic Acid Induces Th1 Responses by Modulating the Function of Dendritic Cells and Ameliorates Th2-Mediated Allergic Airway Inflammation in Mice
  2. Ferulic acid supresses Th2 immune response and prevents remodeling in ovalbumin-induced pulmonary allergy associated with inhibition of epithelial-derived cytokines
  3. Ferulic acid inhibits interleukin 17‐dependent expression of nodal pathogenic mediators in fibroblast‐like synoviocytes of rheumatoid arthritis
  4. Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin
  5. FA15, a hydrophobic derivative of ferulic acid, suppressesinflammatory responses and skin tumorpromotion: comparison with ferulic acid
  6. A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damagecaused by ultraviolet irradiation
  7. Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet‐induced photodamage in human skin
  8. Protective effect of ferulic acid on 7,12-dimethylbenz[a]anthracene-induced skin carcinogenesis in Swiss albino mice
  9. Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms
  10. A comparison of skin delivery of ferulic acid and its derivatives: Evaluation of their efficacy and safety
  11. Skin Delivery of Ferulic Acid from Different Vesicular Systems
  12. Inhibitory effect of topical application of polymerized ferulic acid, a synthetic lignin, on tumor promotion in mouse skin two-stage tumorigenesis
  13. Inhibitory Effect of Ferulic Acid and Isoferulic Acid on Murine Interleukin-8 Production in Response to Influenza Virus Infections in vitro and in vivo
  14. INHIBITORY EFFECT OF FERULIC ACID ON MACROPHAGEINFLAMMATORY PROTEIN-2 PRODUCTION IN A MURINE MACROPHAGE CELL LINE, RAW264.7
  15. Ferulic acid inhibits neuro-inflammationin mice exposed to chronic unpredictable mild stress
  16. Attenuation of chronic neuroinflammation by a nitric oxide‐releasing derivative of the antioxidant ferulic acid
  17. Promising role of ferulic acid, atorvastatin and their combination in ameliorating high fat diet-induced stressin mice
  18. Iron-induced oxidative damage and apoptosis in cerebellar granule cells: attenuation by tetramethylpyrazine and ferulic acid
  19. In vivo protective effects of ferulic acid ethyl ester against amyloid‐beta peptide 1–42‐induced oxidative stress
  20. In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe2+/H2O2: Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders
  21. Ferulic acid inhibits oxidative stress and cell death induced by Ab oligomers: Improved delivery by solid lipid nanoparticles
  22. In vitro and in vivo antioxidant properties of ferulic acid: A comparative study with other natural oxidation inhibitors
  23. Ferulic acid inhibits UV-B–induced oxidative stress in human lymphocytes
  24. Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes
  25. Ferulic Acid Protects Human Umbilical Vein Endothelial Cells from Radiation Induced Oxidative Stress by Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Pathways
  26. Treatment with ferulic acid to rats with streptozotocin-induced diabetes: effects on oxidative stress, pro-inflammatory cytokines, and apoptosis in the pancreatic β cell
  27. Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes
  28. Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes
  29. Ferulic acid protects lymphocytes from radiation-predisposed oxidative stressthrough extracellular regulated kinase
  30. Ferulic Acid: a Natural Antioxidant Against Oxidative Stress Induced by Oligomeric A-beta on Sea Urchin Embryo
  31. Aqueous Extract of Tomato (Solanum lycopersicum L.) and Ferulic Acid Reduce the Expression of TNF-α and IL-1β in LPS-Activated Macrophages
  32. The molecular events behind ferulic acid mediated modulation of IL-6 expression in LPS-activated Raw 264.7 cells
  33. Ferulic acid ameliorates radiation induced duodenal inflammation by modulating nuclear factor Kappa beta-nuclear factor-2 erythroid related factor-2 cross talk
fisetin
  1. Fisetin Promotes Hair Growth by Augmenting TERT Expression
Fucoxanthin ( From Seaweed Extract )
  1. A Marine Carotenoid, Fucoxanthin, Induces Regulatory T Cells and Inhibits Th17 Cell Differentiation in Vitro
  2. Comparative effect of fucoxanthin and vitamin C on oxidative and functional parameters of human lymphocytes
  3. The Suppressive Effect of a Marine Carotenoid, Fucoxanthin, on Mouse Ear Swelling through Regulation of Activities and mRNA Expression of Inflammation-associated Enzymes
  4. Protective Effect of Fucoxanthin against UVB-Induced SkinPhotoaging in Hairless Mice
  5. Anti‐pigmentary activity of fucoxanthin and its influence on skin mRNA expression of melanogenic molecules
  6. Protective and therapeutic effects of fucoxanthin against sunburn caused by UV irradiation
  7. Chemical Stability and Skin Permeation of Fucoxanthin-Loaded Microemulsions
  8. FucoxanthinElicits Epigenetic Modifications, Nrf2 Activation and Blocking Transformation in Mouse Skin JB6 P+ Cells
  9. Fucoxanthin Protects Cultured Human Keratinocytes against Oxidative Stress by Blocking Free Radicals and Inhibiting Apoptosis
  10. Comparative effects of β-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats
  11. Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages
  12. First Evidence for the Anti-inflammatory Activity of Fucoxanthin in High-Fat-Diet-Induced Obesity in Mice and the Antioxidant Functions in PC12 Cells
  13. Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells
  14. Fucoxanthin Ameliorates Inflammation and Oxidative Reponses in Microglia
  15. Anti-Neuroinflammatory Effects of Fucoxanthin via Inhibition of Akt/NF-κB and MAPKs/AP-1 Pathways and Activation of PKA/CREB Pathway in Lipopolysaccharide-Activated BV-2 Microglial Cells
  16. Anti-inflammatory effect of fucoxanthinderivatives isolated from Sargassum siliquastrum in lipopolysaccharide-stimulated RAW 264.7 macrophage
  17. Fucoxanthin Inhibits the Inflammation Response in Paw Edema Model through Suppressing MAPKs, Akt, and NFκB
  18. Protective effects of fucoxanthin against ferric nitrilotriacetate-induced oxidative stressin murine hepatic BNL CL.2 cells
  19. Fucoxanthin restrains Oxidative stress induced by Retinol Deficiency through Modulation of Na+Ka+-ATPase and Antioxidant Enzyme activities in Rats
  20. Fucoxanthin restrains oxidative stress induced by retinol deficiency through modulation of Na+Ka+-ATPase and antioxidant enzyme activities in rats
  21. Protective effect of fucoxanthin isolated from Ishige okamurae against high-glucose induced oxidative stressin human umbilical vein endothelial cells and zebrafish model
  22. Fucoxanthin restrains oxidative stress induced by retinol deficiency through modulation of Na+Ka+-ATPase and antioxidant enzyme activities in rats
  23. Fucoxanthin, a marine carotenoid protects cadmium-induced oxidative renal dysfunction in rats
  24. Fucoxanthin content of Cylindrotheca Closterium and its oxidative stress mediated enhancement
  25. Fucoxanthin, the constituent of Laminaria japonica, triggers AMPK-mediated cytoprotection and autophagy in hepatocytes under oxidative stress
  26. Enhancing colour and oxidative stabilities of reduced-nitrite turkey meat sausages during refrigerated storage using fucoxanthin purified from the Tunisian seaweed Cystoseira barbata
  27. Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo
  28. Fucoxanthin inhibits theinflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages
  29. Low-molecular-weight fucoidan and high-stability fucoxanthin from brown seaweed exert prebiotics and anti-inflammatory activities in Caco-2 cells
  30. Undaria pinnatifida and Fucoxanthin Ameliorate Lipogenesis and Markers of Both Inflammation and Cardiovascular Dysfunction in an Animal Model of Diet-Induced Obesity
  31. Inhibition of Ultraviolet B-Induced Expression of the Proinflammatory Cytokines TNF-α and VEGF in the Cornea by Fucoxanthin Treatment in a Rat Model

 


Ginseng radix

  1. Promotion of hair growth by ginseng radix on cultured mouse vibrissal hair follicles
  2. Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice
  3. Simultaneous analysis of ginsenosides of various ginseng radix by HPLC
  4. Carbon dioxide extraction of ginseng root hair oil and ginsenosides
  5. Comparative Hair Restorer Efficacyof Medicinal Herb on Nude (Foxn) Mice
  6. Protective effect of Korean Red Ginseng against chemotherapeutic drug-induced premature catagen development assessed with human hair follicle organ culture model
  7. Compositions and methods of inducing hair growth utilizing Continus coggygria
  8. HairGrowth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
  9. Determinations of Trilinolein and 1,2– Dilinoleoyl-3-Oleoyl-Glycerol in Various Panax Ginseng by HPLC
  10. Panax ginseng extract antagonizes the effect of DKK‑1-induced catagen-like changes of hair follicles
  11. Experimental Study on the Effects of the Extract of Ginseng Radixet Rhizoma on Hair Growth of C57BL/6J Mice
  12. Introduction of hemopoiesis by Saenghyuldan a mixture of Ginseng Radix, Paeoniae Radix Alba, and Hominis Placenta Extracts.
  13. The Effects of Ginseng Radix Rubra on Human Vascular Endothelial Cells
  14. Effect of Radix Ginseng and Radix Trichosanthis on the Melanogenesis
  15. Effects of Red Ginseng extract on ultraviolet B‐irradiated skin change in C57BL mice
  16. Effects of EGb 761 and Korean Red Ginseng on Melanogenesis in B16F10 Melanoma Cells and Protection Against UVB Irradiation in Murine Skin
  17. Protective effects of Panax ginseng on muscle injury and inflammation after eccentric exercise
  18. The chemopreventive potential and anti-inflammatory activities of Korean black ginseng in colon26-M3.1 carcinoma cells and macrophages
  19. Anti-inflammatory mechanism of ginsengsaponins in activated microglia
  20. COMBINATION EFFECTS OF SHOSAIKOTO (CHINESE TRADITIONAL MEDICINE) AND PREDNISOLONE ON THE ANTI-INFLAMMATORY ACTION
  21. Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells
  22. TheEffectsofKoreanRedGinseng(GinsengRadixRubra)onLiverRegenerationafterPartialHepatectomyinDogs
  23. Pectinase-Processed Ginseng Radix (GINST) Ameliorates Hyperglycemia and Hyperlipidemia in High Fat Diet-Fed ICR Mice
  24. Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anti-Oxidative Activities
  25. A Natural Compound (Ginsenoside Re) Isolated from Panax ginseng as a Novel Angiogenic Agentfor Tissue Regeneration
  26. Effects of the Chinese Herbal Medicines Bupleuri radix, Ginseng radix,and Zingiberis rhizoma on Lymphatic Vessel Activity in Rats
  27. Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines
  28. Anti-Inflammatory and Antimicrobial Effects of a Novel Herbal Formulation (WSY-1075) in a Chronic Bacterial Prostatitis Rat Model
  29. Effect of Korean Red Ginseng on Testicular Tissue Injuryafter Torsion and Detorsion
  30. Neuroprotection in Diabetic Encephalopathy
  31. Ginseng radix induces apoptosis in HL-60 cells and its mechanism as little relation with TNF-α production
Glycyrrhiza glabra root extract
  1. Angiogenic and proliferative effects of the cytokineVEGF in Ehrlich ascites tumor cells is inhibited by Glycyrrhiza glabra
  2. Licocalchone-C Extracted from Glycyrrhiza GlabraInhibits Lipopolysaccharide-Interferon-γ Inflammation by Improving Antioxidant Conditions and Regulating Inducible Nitric Oxide Synthase Expression
  3. Glycyrrhiza glabra L. Extract Inhibits LPS-Induced Inflammation in RAW Macrophages
  4. A Licorice Extract Reduces Lipopolysaccharide‐Induced Proinflammatory Cytokine Secretion by Macrophages and Whole Blood
  5. Hair Growth Promotant Activity of Petroleum Ether Root Extract of Glycyrrhiza Glabra L (Fabaceae) in Female Rats
  6. HAIR GROWTH STIMULATING EFFECT AND PHYTOCHEMICAL EVALUATION OF HYDRO-ALCOHOLIC EXTRACT OF GLYCYRRHIZA GLABRA
  7. GLYCYRRHIZA GLABRA EXTRACT CREAM: EFFECTS ON SKIN PIGMENT “MELANIN”
  8. Modulation of lipopolysaccharide-induced pro-inflammatory mediators by an extract of Glycyrrhiza glabra and its phytoconstituents
  9. Protection of Mitochondrial Functions against Oxidative Stresses by Isoflavans from Glycyrrhiza glabra
  10. Protective activity of Glycyrrhiza glabra Linn. on carbon tetrachloride-induced peroxidative damage
  11. Anti-convulsant action and amelioration of oxidative stress by Glycyrrhiza glabra root extract in pentylenetetrazole- induced seizure in albino rats
  12. In vitro studies on protective effect of Glycyrrhiza glabra root extracts against cadmium-induced genetic and oxidative damage in human lymphocytes
  13. Amelioration of oxidative stress induced by oxidative mutagens and COX-2 inhibitory activity of umbelliferone isolated from Glycyrrhiza glabra L
  14. In vivoantioxidant and hepatoprotective potential of Glycyrrhiza glabraextract on carbon tetra chloride(CCl4)induced oxidative-stress mediated hepatotoxicity
  15. Modulation of genotoxicity of oxidative mutagens by glycyrrhizic acid from Glycyrrhiza glabra L.
  16. New insights into the antioxidant and apoptotic potential of Glycyrrhiza glabra L. during hydrogen peroxide mediated oxidative stress: An in vitro and in silico evaluation
  17. The Effects of Glycyrrhiza glabra L. extract use with aerobic training on inflammatory factors and cognitive state in elderly with mild cognitive impairment
  18. Anti-Inflammatory Effects of Glycyrrhiza glabra Linne Extract in a Dextran Sulfate Sodium-Induced Colitis Mouse Model
proanthocyanidin ( From Grape seed extract )
  1. Grape seed proanthocyanidin extract (GSPE)differentially regulates Foxp3+ regulatory and IL-17+ pathogenic T cell in autoimmune arthritis
  2. Proanthocyanidins from the bark of Metasequoia glyptostroboides ameliorate allergic contact dermatitis through directly inhibiting T cells activation and Th1/Th17 responses
  3. Grape seed proanthocyanidin extract has potent anti-arthritic effects on collagen-induced arthritis by modifying the T cell balance
  4. Grape Seed Proanthocyanidin Extract Protects Against Carrageenan-Induced Lung Inflammation in Mice Through Reduction of Pro-inflammatory Markers and Chemokine Expressions
  5. Proanthocyanidins: novel treatment for psoriasis that reduces oxidative stress and modulates Th17 and Treg cells
  6. Grape-Seed Proanthocyanidin Extract as Suppressors of Bone Destruction inInflammatory Autoimmune Arthritis
  7. Anti-Inflammatory Activity of a Polymeric Proanthocyanidin from Serjania schiedeana
  8. Grape seed proanthocyanidin extract inhibits interleukin-17-induced interleukin-6 production via MAPK pathway in human pulmonary epithelial cells
  9. Effects of grape seed proanthocyanidin extract on airway inflammation and Treg/Th17 balance in asthmatic mice
  10. Anti-inflammatory and Anti-melanogenic Proanthocyanidin Oligomers from Peanut Skin
  11. Dietary grape-seed proanthocyanidin inhibition of ultraviolet B-induced immune suppression is associated with induction of IL-12
  12. Grape Seed Proanthocyanidin Extract Attenuates Allergic Inflammation in Murine Models of Asthma
  13. Protective Effects of Proanthocyanidin on Cerulein-induced Acute Pancreatic Inflammation in Rats
  14. Grape Seed Proanthocyanidin Extract Attenuates Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma by Downregulating Inducible Nitric Oxide Synthase
  15. Cranberry proanthocyanidins inhibit the adherence properties of Candida albicans and cytokine secretion by oral epithelial cells
  16. Proanthocyanidin protects against cisplatin‐induced oxidative liver damage through inhibition of inflammation and NF‐κβ/TLR‐4 pathway
  17. Proanthocyanidin from grape seed extract inhibits airway inflammation and remodeling in a murine model of chronic asthma.
  18. Grape Seed Proanthocyanidin Extract–Mediated Regulation of STAT3 Proteins Contributes to Treg Differentiation and Attenuates Inflammation in a Murine Model of Obesity-Associated Arthritis
  19. Grape seed proanthocyanidin extract ameliorates inflammation and adiposity by modulating gut microbiota in high‐fat diet mice
  20. Anti-inflammatory effects of proanthocyanidin-rich red rice extract via suppression of MAPK, AP-1 and NF-κB pathways in Raw 264.7 macrophages
  21. Gastroprotective Effects of Grape Seed Proanthocyanidin Extracts against Nonsteroid Anti-Inflammatory Drug-Induced Gastric Injury in Rats
  22. Comparison of the Anti-inflammatory Effects of Proanthocyanidin, Quercetin, and Damnacanthal on Benzo(a)pyrene Exposed A549 Alveolar Cell Line
  23. Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats
  24. Effects of Grape Seed Proanthocyanidin Extract on Oxidative Stress Induced by Diabetes in Rat Kidney
  25. Back‐regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy
  26. Protection of Primary Glial Cells by Grape Seed Proanthocyanidin Extract against Nitrosative/ Oxidative Stress
  27. Low molecular proanthocyanidin dietary biofactor Oligonol: Its modulation of oxidative stress, bioefficacy, neuroprotection, food application and chemoprevention potentials
  28. Proanthocyanidin prevents methotrexate-induced intestinal damage and oxidative stress
  29. Activin, a Grape Seed-derived ProanthocyanidinExtract, Reduces Plasma Levels of Oxidative Stress and Adhesion Molecules (ICAM-1, VCAM-1 and E-selectin) in Systemic Sclerosis
  30. Acute and chronic stress-induced oxidativegastrointestinal injury in rats, and the protective ability of a novel grape seed proanthocyanidin extract
  31. Oral Administration of Grape Seed Proanthocyanidin Extracts Downregulate RAGE Dependant Nuclear Factor- Kappa BP65 Expression in the Hippocampus of Streptozotocin Induced Diabetic Rats
  32. Effect of Proanthocyanidin on Expression of Nuclear Factor kappa B and Interleukin-6 in Rats after Spinal Cord Injury
Hesperidin ( From Citrus Aurantium Extract )
  1. Hesperidin inhibits development of atopic dermatitis-like skin lesions in NC/Nga mice by suppressing Th17 activity
  2. Antiasthmatic Effects of Hesperidin, a Potential Th2 Cytokine Antagonist, in a Mouse Model of Allergic Asthma
  3. Hesperidin ameliorates immunological outcome and reduces neuroinflammation in the mouse model of multiple sclerosis
  4. Hesperidin methyl chalcone inhibits oxidative stress and inflammation in a mouse model of ultraviolet B irradiation-induced skin damage
  5. Experimental immunology
    Differential effect of hesperidin on Th1, Th2, Th17, and proinflammatory cytokines production from splenocyte of Schistosoma mansoni-infected mice
  6. Hesperidin protects gentamicin-induced nephrotoxicity via Nrf2/HO-1 signaling and inhibits inflammation mediated by NF-κB in rats
  7. Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats
  8. Hesperidin inhibits expression of hypoxia inducible factor-1 alpha and inflammatory cytokine productionfrom mast cells
  9. Oral administration of hesperidin, a citrus flavonone, in ratscounteracts the oxidative stress, the inflammatory cytokineproduction, and the hepatotoxicity induced by the ingestion of2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
  10. Hesperidin reverses cognitive and depressive disturbances induced by olfactory bulbectomy in mice by modulating hippocampal neurotrophins and cytokine levels and acetylcholinesterase activity
  11. Hesperidin Suppresses Ovalbumin-Induced Airway Inflammation in a Mouse Allergic Asthma Model
  12. Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation of PPARγ and abrogation of oxidative stress and inflammation
  13. Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio
  14. Antiinflammatory Effects of Traditional Korean Medicine, JinPi‐tang and Its Active Ingredient, Hesperidin in HaCaT cells
  15. Antioxidant and anti-inflammatory potential of hesperidin against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced experimental Parkinson’s disease in mice
  16. Exposure to Zinc Oxide Nanoparticles Induces Neurotoxicity and Proinflammatory Response: Amelioration by Hesperidin
  17. HesperidinAlleviates Lipopolysaccharide-Induced Neuroinflammation in Mice by Promoting the miRNA-132 Pathway
  18. Hesperidin ameliorates UV radiation-induced skin damage by abrogation of oxidative stress andinflammatory in HaCaT cells
  19. Hesperidin alleviates rat postoperative ileus through anti-inflammation and stimulation of Ca2+-dependent myosin phosphorylation
  20. Evaluation of antioxidative and anti-inflammatorypotential of hesperidin and naringin on the rat air pouch model of inflammation
  21. Inhibitory effect of Hesperidin on tumour initiation and promotion in mouse skin
  22. Preventive effect of hesperidin against inflammation in CD-1 mouse skin caused by tumor promoter.
  23. Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice
  24. Topical hesperidin improves epidermal permeability barrier function and epidermal differentiation in normal murine skin
  25. Capillary resistance in the skin of rats fed flavone-free and atherogenic diets, and their response to hesperidin-methyl-chalcone.
  26. Topical formulation containing hesperidin methyl chalcone inhibits skin oxidative stress and inflammation induced by ultraviolet B irradiation
  27. Topical hesperidin prevents glucocorticoid‐induced abnormalities in epidermal barrier function in murine skin
  28. Detection of Hesperidin in Orange Skin by the UV-VIS Spectrophotometry
  29. Hesperidin Suppresses Melanosome Transport by Blocking the Interaction of Rab27A-Melanophilin
  30. Effect of topical application of hesperidin, aescin and tanshinone on finger nailfold skin microcirculation
  31. Articels : Hesperidin Improves the IL-6-Mediated Hepatic Insulin Resistance in Hepa-1c1c7 Cells
  32. Articels : Hesperidin Ameliorates TNF-α-Mediated Insulin Resistance in Differentiated 3T3-L1 Cells
  33. Effect of hesperidin on lipid peroxidation and TNF-α of alcoholic fatty liver disease in rats
  34. Effect Of Hesperidin In Bleomycin-Induced Pulmonary Fibrosis In Rats: Critical Role Of NRF-2, TNF-Α, AND IL-1Β
  35. Influence of Hesperidin Pretreatment on the Expression of TNF-α and IFN-γ in Concanavalin A-induced Acute Liver Injury in Mice
  36. Influence of Hesperidin on the Expression of TNF-α and IFN-γ in Concanavalin Ainduced Acute Liver Injury in Mice
  37. Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test

 


Hibiscus rosa-sinensis L. flowers

  1. Characterization of the mucilages extracted from hibiscus rosa-sinensis linnand hibiscus mutabilis linn and their skin moisturizing effect
  2. Antidepressant-like activityof anthocyanidins from Hibiscus rosa-sinensis flowers in tail suspension test and forced swim test
  3. ANTI-INFLAMMATORY EFFECTS OFHIBISCUS ROSA-SINENSIS L. AND Hibiscus ROSA-SINENSIS VAR.ALBAETHANOL EXTRACTS
  4. Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn. leaves in experimental colitis in rats
  5. A survey on Hibiscus rosa—sinensis, Alcea rosea L. and Malva neglecta Wallr as antibacterial agents
  6. Antihyperlipidemic Effect ofEthanolic Extract of Hibiscus rosa sinensisFlowers in Hyperlipidemic Rats
  7. Study on prevention of two-stage skin carcinogenesis by Hibiscus rosa sinensis extract and the role of its chemical constituent, gentisic acid, in the inhibition of tumour promotion response and oxidative stress in mice
  8. Antioxidant and antibacterial activities of Hibiscus Rosa-sinensis Linn flower extracts
  9. Mechanisms Involved in Toxicity of Liver Caused by Piroxicam in Mice and Protective Effects of Leaf Extract of Hibiscus Rosa-Sinensis L.
  10. ANTI-PYRETIC ACTION OF CAULERPA LENTILLIFERA, HIBISCUS ROSA-SINENSIS, AND PIPER SARMENTOSUM AQUEOUS EXTRACT IN MICE
  11. Evaluation of Antioxidant,Toxicological and wound healing Properties of Hibiscus rosa-sinensisL.(Malvaceae) ethanolic leaves extract on different Experimental animal models
  12. Polyphenols rich Hibiscus rosa sinensis Linn. petals modulate diabetic stress signalling pathways in streptozotocin-induced experimental diabetic rats
  13. Gastroprotective effect of flower extracts of Hibiscus rosa sinensis against acute gastric lesion modelsin rodents
  14. Antibacterial, antioxidant and phytochemical screening of Hibiscus rosa sinensis, Acorus calamus, Cucurbita maxima and Moringa oliefera
  15. EVALUATION OF ANTI INFLAMMATORY ACTIVITY OF HIBISCUS ROSA SINENSIS Linn. FLOWER EXTRACT IN RATS.
  16. In-vitro antioxidant activityand phytochemical analysis in extracts of Hibiscus rosa-sinensis stem and leaves
  17. Hypoglycemic and hypolipidemic activity of Hibiscus rosa sinensis Linn on streptozotocin–induced diabetic rats
  18. In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn.
  19. The Floral Nectaries of Hibiscus rosa-sinensis: 1. Development of the Secretory Hairs
  20. Traditional medicinal uses of Hibiscus rosa-sinensis
  21. Effect of ethanolic extract of Hibiscus rosa sinensis L.,flowers on hair growth in female wistar rats
  22. Preparation, evaluation and hair growth stimulating activity of herbal hair oil
  23. Hibiscus rosa sinensis Linn – ‘‘Rudrapuspa’’ : A Review
  24. Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
  25. Comparative Screening of Immunomodulatory Activity of Hydro-alcoholic Extract ofHibiscus rosa sinensis Linn. and Ethanolic Extract of Cleome gynandra Linn
  26. Cytotoxicity of Hibiscus rosa-sinensis flower extract
  27. Evaluation of the wound-healing activity of Hibiscus rosa sinensis L (Malvaceae) in Wistar albino rats
  28. Evaluation of comparative antioxidant potential of four cultivars of Hibiscus rosa-sinensis L. by HPLC-DPPH method
  29. Effect of Hibiscus rosa sinensis Extract on Hyperproliferation and Oxidative Damage Caused by Benzoyl Peroxide and Ultraviolet Radiations in Mouse Skin
  30. Preliminary phytochemical and antiulcer studies of Hibiscus rosa sinensis Linn. root extracts
  31. Functional Jelly Drink as Source of Dietary Fiber and Vitamin C Consisting of Kappa Carrageenan, Konjac Glucomannan and Hibiscus sabdariffa, Linn Extract


Houttuynia cordata

  1. Effect of Herbal Complex Extract Including Houttuynia cordata Thunb on Hair Growth Promotion in C57BL/6 Mice
  2. Structures, Components and Functions of Secretory Tissues in Houttuynia cordata
  3. Antioxidative Effects of Polyphenols in Leaves of Houttuynia cordata on Protein Fragmentation by Copper–Hydrogen Peroxide In Vitro
  4. Houttuynia cordataThunb: A Review of Phytochemistry and Pharmacology and Quality Control
  5. Screening of Some Crude Plant Extracts for Their Acaricidal and Insecticidal Efficacies
  6. Hair growth inhibitors and compositions containing the same
  7. Determination of As,Hg and 666,DDT of different Houttuynia cordata Accessions
  8. Antiproliferative Activityand Induction of Apoptosis in Human Melanoma Cellsby Houttuynia cordataThunb Extract
  9. Antioxidants for Healthy Skin: The Emerging Role of Aryl Hydrocarbon Receptors and Nuclear Factor-Erythroid 2-Related Factor-2
  10. Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growthin Conjunction with Wnts Signaling
  11. An Asian traditional herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta and green tea stimulates hair growth in mice
  12. Anti-inflammatory effects of a Houttuynia cordatasupercritical extract
  13. Flavonoids from the aerial parts of Houttuynia cordataattenuate lung inflammation in mice
  14. Protective effects from Houttuynia cordata aqueous extract against acetaminophen-induced liver injury
  15. Houttuynia cordata Thunb inhibits the production of pro‑inflammatory cytokines through inhibition of the NFκB signaling pathway in HMC‑1 human mast cells
  16. Anti-inflammatory effects of Houttuynia cordatasupercritical extract in carrageenan-air pouch inflammation model
  17. Anti-Neuroinflammatory Effects of Houttuynia cordata Extract on LPS-Stimulated BV-2 Microglia
  18. In vitro and Ex vivo Supplementation of Houttuynia cordata Extract and Immunomodulating Effect in Mice
  19. Protective effects of Houttuynia cordataaqueous extract in mice consuming a high saturated fat diet
  20. An ethyl acetate fraction derived from Houttuynia cordata extract inhibits the production of inflammatory markers by suppressing NF-кBand MAPK activation in lipopolysaccharide-stimulated RAW 264.7 macrophages
  21. Houttuynia cordata Thunb reverses oxaliplatin-induced neuropathic pain in rat by regulating Th17/Treg balance
  22. Paeonia japonica, Houttuynia cordata, and Aster scaber Water Extracts Induce Nitric Oxide and Cytokine Production by Lipopolysaccharide-Activated Macrophages
  23. Houttuynia cordata aqueous extract attenuated glycative and oxidative stress in heart and kidney of diabetic mice
  24. Effect of Natural Extracts Mixture from Houttuynia cordataand Ulmus davidiana var. japonica in Mast Cell-Induced Allergic Inflammatory Response
  25. Vaginal innate immune mediators are modulated by a water extract of Houttuynia cordata Thunb
  26. Houttuynia cordata suppresses the Aggregatibacter actinomycetemcomitans-induced increase of inflammatory-related genes in cultured human gingival epithelial cells
  27. Houttuynia cordata water extract suppresses anaphylactic reaction and IgE-mediated allergic response by inhibiting multiple steps of FcεRI signaling in mast cells
  28. Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A review
  29. Anti-Inflammatory Activity of Houttuynia cordata against Lipoteichoic Acid-Induced Inflammation in Human Dermal Fibroblasts
  30. Pharmaceutical Impact of Houttuynia Cordata and Metformin Combination on High-Fat-Diet-Induced Metabolic Disorders: Link to Intestinal Microbiota and Metabolic Endotoxemia
  31. Effects of Volatile Oil and 2-Undecanone from Houttuynia Cordata Thunb. on LPS-TLR4/MD-2-TNF-α Inflammation Signaling Pathway
hydroxytyrosol ( From Olive Leaf Extract )
  1. Use of hydroxytyrosol as anti-aging agent
  2. Peracetylated hydroxytyrosol, a new hydroxytyrosol derivate, attenuates LPS-inducedinflammatoryresponse in murine peritoneal macrophages via regulation of non-canonical inflammasome, Nrf2/HO1 and JAK/STAT signaling pathways
  3. Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis
  4. Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol
  5. Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol
  6. Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells
  7. Hydroxytyrosol Is the Major Anti-Inflammatory Compound in Aqueous Olive Extracts and Impairs Cytokine and Chemokine Production in Macrophages
  8. Effects of hydroxytyrosol‐20 on carrageenan‐induced acute inflammation and hyperalgesia in rats
  9. Suppressive Effects of Hydroxytyrosol on Oxidative Stress and Nuclear Factor-κB Activation in THP-1 Cells
  10. Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD
  11. Oleic acid, hydroxytyrosol and n-3 fatty acids collectively modulate colitis through reduction of oxidative stress and IL-8 synthesis; in vitro and in vivo studies
  12. Anti-inflammatory activity of hydroxytyrosol – Inhibition of cytokine production in a parkinson’s model system of neuroinflammation
  13. Role of the inhibition of oxidative stress and inflammatory mediators in the neuroprotective effects of hydroxytyrosol in rat brain slices subjected to hypoxia reoxygenation
  14. Nutritionally relevant concentrations of resveratrol and hydroxytyrosol mitigate oxidative burst of human granulocytes and monocytes and the production of pro-inflammatory mediators in LPS-stimulated RAW 264.7 macrophages
  15. Quercetin and hydroxytyrosolattenuates xanthine/xanthine oxidase-induced toxicity in H9c2 cardiomyocytes by regulation of oxidative stress and stress-sensitive signaling pathways
  16. Anti-Inflammatory and Antitumor Effects of Hydroxytyrosol but Not Oleuropein on Experimental Glioma In Vivo. A Putative Role for the Renin-Angiotensin System
  17. Hydroxytyrosol exerts an anti-inflammatory effect by suppressing Toll-like receptor 2 and TLR 2 downstream pathways in Staphylococcus aureus-induced mastitis in mice
  18. Hydroxytyrosol inhibits the inflammatory response of osteoarthritis chondrocytes via SIRT6-mediated autophagy
  19. Antiproliferative, Antioxidant and Anti-inflammatoryEffects of Hydroxytyrosol on Human Hepatoma HepG2 and Hep3B Cell Lines
  20. Influence of olive-derived hydroxytyrosol on the toll-like receptor 4-dependentinflammatory response of mouse peritoneal macrophages
  21. Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death
  22. Hydroxytyrosol and oleuropein from olive leaves: Potent anti-inflammatory andanalgesic activities
  23. Olive Phenol Hydroxytyrosol Prevents Passive Smoking–Induced Oxidative Stress
  24. Hydroxytyrosol protects retinal pigment epithelial cells from acrolein‐induced oxidative stress and mitochondrial dysfunction
  25. Olive oil hydroxytyrosolprotects human erythrocytes against oxidative damages
  26. Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways
  27. The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NO• response of isolated rat aorta
  28. Protective effect of hydroxytyrosoland tyrosol against oxidative stress in kidney cells
  29. Olive oil hydroxytyrosol reduces toxicity evoked by acrylamide in human Caco-2 cells by preventing oxidative stress
  30. Protective Effects of Synthetic Hydroxytyrosol Acetyl Derivatives against Oxidative Stress in Human Cells
  31. The hydroxytyrosol-dependent increase of TNF-α in LPS-activated human monocytes is mediated by PGE2 and adenylate cyclase activation
  32. Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways

Hydroxygenkwanin

Icariin ( From Horny Goat Weed Extract )
  1. Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin
  2. Regulation of Th17/Treg function contributes to the attenuation of chronic airway inflammation by icariinin ovalbumin-induced murine asthma model
  3. A natural flavonoid glucoside icariin inhibits Th1 and Th17 cell differentiation and ameliorates experimental autoimmune encephalomyelitis
  4. A Natural Flavonoid Glucoside, Icariin, Regulates Th17and Alleviates Rheumatoid Arthritis in a Murine Model
  5. Icariin inhibits LPS-induced cell inflammatory response by promoting GRα nuclear translocation and upregulating GRα expression
  6. Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model
  7. Icariin prevents cytokine‑induced β‑cell death by inhibiting NF‑κB signaling
  8. Icariin inhibits TNF-α/IFN-γ inducedinflammatoryresponse via inhibition of the substance P and p38-MAPK signaling pathway in human keratinocytes
  9. Icariin promotes mouse hair follicle growth by increasing insulin‐like growth factor 1 expression in dermal papillary cells
  10. Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway
  11. Effects of Icariin on Hypothalamic-Pituitary-Adrenal Axis Action and Cytokine Levels in Stressed Sprague-Dawley Rats
  12. Icariin Regulates Expression of Cytokines in Osteoblasts
  13. Icariin protects against titanium particle-induced osteolysis and inflammatory responsein a mouse calvarial model
  14. Effects of icariin on cytokine-induced ankylosing spondylitis with fibroblastic osteogenesis and its molecular mechanism
  15. Attenuation of LPS-induced inflammation by ICT, a derivate of icariin, via inhibition of the CD14/TLR4 signaling pathway in human monocytes
  16. Icariin Attenuates High-cholesterol Diet Induced Atherosclerosis in Rats by Inhibition of InflammatoryResponse and p38 MAPK Signaling Pathway
  17. Inhibitory effects of icariin on melanogenesisof human epidermal melanocytes
  18. Icariin inhibits inflammation via immunomodulation of the cutaneous hypothalamus–pituitary–adrenal axis in vitro
  19. Icariin Attenuates Interleukin-1β-InducedInflammatory Response in Human Nucleus Pulposus Cells
  20. [Effects of icariin on inflammation model stimulated by lipopolysaccharide in vitro and in vivo].
  21. Icariin attenuates LPS-induced acuteinflammatoryresponses: Involvement of PI3K/Akt and NF-κB signaling pathway
  22. Inhibitory effect of icariin on Ti-inducedinflammatoryosteoclastogenesis
  23. Icariinprotects murine chondrocytes from lipopolysaccharide-inducedinflammatory responses and extracellular matrix degradation
  24. Effects of icariin combined with Panax notoginseng saponins on ischemia reperfusion‐induced cognitive impairments related with oxidative stress and CA1 of hippocampal neurons in rat
  25. Icariin Promotes Angiogenic Differentiation andPrevents Oxidative Stress-Induced Autophagy inEndothelial Progenitor Cells
  26. Icariin attenuates hypoxia‐induced oxidative stress and apoptosis in osteoblasts and preserves their osteogenic differentiation potential in vitro
  27. [Icariin reduces mitochondrial oxidative stress injury in diabetic rat hearts].
  28. Icariinexerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation
  29. Protective effect of icariin on DNA against radical‐induced oxidative damage
  30. Icariin attenuated oxidative stressinduced-cardiac apoptosis by mitochondria protection and ERK activation
  31. STUDY OF SYNERGISTIC EFFECTS OF ICARIIN ON INDUCING IL-2、3、 6
  32. Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells
  33. Icariin Intervenes in Cardiac Inflammaging through Upregulation of SIRT6 Enzyme Activity and Inhibition of the NF-Kappa B Pathway
  34. Icariin ameliorates IgA nephropathy by inhibition of nuclear factor kappa b/Nlrp3 pathway
  35. Icariin improves Fanconi anemia hematopoietic stem cell function through SIRT6-mediated NF-kappa B inhibition


Isorhapontigenin ( From Gnetum montanum extract )

  1. Agent for hair deforming treatment
  2. Phytochemistry and Biological Activity Perspectives of Rheum Species
  3. Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid‐independent mechanism
  4. Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats
  5. Effect of isorhapontigenin on respiratory burst of rat neutrophils
  6. Piceatannol and Its Metabolite, Isorhapontigenin, Induce SIRT1 Expression in THP-1 Human Monocytic Cell Line
  7. An Isorhapontigenin Tetramer and a Novel Stilbene Dimer from Gnetum hainanense
  8. The Chinese Herb Isolate Isorhapontigenin Induces Apoptosis in Human Cancer Cells by Down-regulating Overexpression of Antiapoptotic Protein XIAP
  9. Studies on formic acid-catalyzed dimerization of isorhapontigenin and of resveratrol to tetralins
  10. Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways
  11. Administration of the Resveratrol Analogues Isorhapontigenin and Heyneanol-A Protects Mice Hematopoietic Cellsagainst Irradiation Injuries
  12. Quantum Chemical Study on the Antioxidation Mechanism of Piceatannol and Isorhapontigenin toward Hydroxyl and Hydroperoxyl Radicals
  13. A Theoretical Study on the Antioxidant Activity of Piceatannol and Isorhapontigenin Scavenging Nitric Oxide and Nitrogen Dioxide Radicals
  14. Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative
  15. [Transport mechanism of isorhapontigenin based on human intestinal Caco-2 cells].
  16. Induction of miR-137 by Isorhapontigenin (ISO) Directly Targets Sp1 Protein Translation and Mediates Its Anticancer Activity Both In Vitro and In Vivo


Kaempferol ( From Galanga Extract )

  1. Dietary Flavonoids as Therapeutics for Preterm Birth: Luteolin and Kaempferol Suppress Inflammation in Human Gestational Tissues In Vitro
  2. Protective Effects of Kaempferol on Lipopolysaccharide-Induced Mastitis in Mice
  3. [Inhibitory effect of kaempferol on inflammatory responseof lipopolysaccharide-stimulated human mast cells].
  4. Dietary Kaempferol Suppresses Inflammation of Dextran Sulfate Sodium-Induced Colitis in Mice
  5. Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Responsein Cardiac Fibroblasts
  6. Kaempferol pretreatment modulates systemic inflammation and oxidative stress following hemorrhagic shock in mice
  7. Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury
  8. Kaempferol Promotes Transplant Tolerance by Sustaining CD4+FoxP3+ Regulatory T Cells in the Presence of Calcineurin Inhibitor
  9. Kaempferol Inhibits P. intermedia Lipopolysaccharide‐Induced Production of Nitric Oxide Through Translational Regulation in Murine Macrophages: Critical Role of Heme Oxygenase‐1‐Mediated ROS Reduction
  10. STAT3 and NF-κB are common targets for kaempferol-mediated attenuation of COX-2 expression in IL-6-induced macrophages and carrageenan-induced mouse paw edema
  11. Inhibition of LPS induced iNOS, COX-2 and cytokines expression by kaempferol-3-O-β-D-sophoroside through the NF-κB inactivation in RAW 264.7 cells [2008]
  12. Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells
  13. Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway
  14. Kaempferol inhibits the production of ROS to modulate OPN–αvβ3 integrin pathway in HUVECs
  15. Kaempferol impedes IL-32-induced monocyte-macrophage differentiation
  16. Kaempferol slows intervertebral disc degeneration by modifying LPS-induced osteogenesis/adipogenesis imbalance and inflammation responsein BMSCs
  17. Expression of the xenobiotic metabolizing enzyme cytochrome P450 1B1 alters anti-inflammatory activity of quercetin, kaempferol and taxifolin in macrophage and monocyte (830.25)
  18. Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells
  19. Kaempferol7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages
  20. Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
  21. Hair Growth Promotingand Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet
  22. Inhibitory effectsof quercetin and Kaempferol as two propolis derived flavonoids on Tyrosinase enzyme
  23. Methods and compounds for reducing allergic reactions to hair dyes
  24. Mechanism of action of herbs and their active constituents used in hair loss treatment
  25. Protection of burn-induced skin injuries by the flavonoid kaempferol
  26. Stimulating effect of kaempferoland six traditional Chinese medicines on activation of tyrosinase
  27. Method For Preparing Kaempferol-3-0-Rutinoside and Composition of Skin External Application Comprising Thereof
  28. Kaempferol Regulates Collagen Induced Oxidation of SHP-2 in Platelet Activation
  29. Antioxidant and Neuroprotective Effects of Kaempferol and Tannic Acid against 6-Hydroxydopamine-induced Oxidative Stress
  30. Composition for preventing hair loss and stimulating hair growth
  31. Kaempferol attenuates COX-2 expression in IL-6-induced macrophages and carrageenan-induced mouse paw edema by targeting STAT3 and NF-kB
  32. Down-regulation of iNOS and TNF-α expression by kaempferol via NF-κB inactivation in aged rat gingival tissues
  33. Downregulation in the mRNA expression of nuclearhormone receptor liver-X-receptor alpha (LXR-ααααα) byTNF-ααααα is abolished by the antioxidant kaempferol, butnot ascorbic acid, in human hepatocarcinoma HepG2cells
  34. Nicotinic acid, lauric acid and kaempferol abolish ATP-binding cassette transporter subfamily A member 1 (ABCA1) down-regulation by TNF-αin hepatocarcinoma HepG2 cell line.
  35. Inhibition of LPS induced iNOS, COX-2 and cytokines expression by kaempferol-3-O-β
    -D-sophoroside through the NF−κB
    inactivation in RAW 264.7 cells


Kolaviron ( From Garcinia kola seeds )

  1. Effects of Kolaviron, the Major Constituent of Garciniakola, on the Histology of the Hypothalamus, Pituitary, and Testes Using Adult Male WistarRats as a Model Organism
  2. Hair growth compositionsand methods of use
  3. Oral phenytoin protects against experimental cyclophosphamide-chemotherapy induced hair loss
  4. Kolaviron-Induced Inhibition of Lung Adencarcinoma (H1299) Cell Growth and Survival via PKA/PI3K Pathway
  5. Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophagesby combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK
  6. Kolaviron, a Garcinia biflavonoid complex ameliorates hyperglycemia-mediated hepatic injury in rats via suppression of inflammatory responses
  7. Inhibition of neuroinflammation in BV2 microglia by the biflavonoid kolavironis dependent on the Nrf2/ARE antioxidant protective mechanism
  8. Kolaviron protects against benzo[a]pyrene-induced functional alterationsalong the brain-pituitary-gonadal axis in male rats
  9. Anti-inflammatory effects of kolaviron modulate the expressions of inflammatory marker genes, inhibit transcription factors ERK1/2, p-JNK, NF-κB, and activate Akt expressions in the 93RS2 Sertoli cell lines
  10. Kolaviron and selenium reduce hydrogen peroxide-induced alterations of the inflammatory response
  11. The effects of Kolaviron, a Natural Flavonoid from the Seeds of Garcinia Kola on LPS-induced Inflammation in Macrophages
  12. Kolaviron Reduces Cadmium-induced Cytotoxicity and Production of Reactive Oxygen Species by Suppressing Inflammatory Response
  13. Neuroprotective role of kolaviron in striatal redo-inflammation associated with rotenone model of Parkinson’s disease
  14. Effects of kolaviron–a Garcinia kola biflavonoid on biochemical and histological parameters in streptozotocin – induced diabetes and diabetic complications (nephrotoxicity and hepatotoxicity) in male Wistar rats
  15. Renoprotection of Kolaviron against benzo (A) pyrene-induced renal toxicity in rats
  16. Kolaviron, a Natural Antioxidant and Anti‐InflammatoryPhytochemical Prevents Dextran Sulphate Sodium‐Induced Colitis in Rats
  17. Analgesic and anti-inflammatory effects of kaviiron (a Garcinia kola seed extract)
  18. Kolaviron, a biflavonoid complex of Garcinia kola seeds modulates apoptosis by suppressing oxidative stress and inflammationin diabetes-induced nephrotoxic rats
  19. Kolaviron Improved Resistance to Oxidative Stress and Inflammationin the Blood (Erythrocyte, Serum, and Plasma) of Streptozotocin-Induced Diabetic Rats
  20. Anti-inflammatory activities of a kolaviron-inhibition of nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production in activated macrophage-like cell line.
  21. Kolaviron Improves Morbidity and Suppresses Mortality by Mitigating Oxido-Inflammation in BALB/c Mice Infected with Influenza Virus
  22. ANTI‐OXIDANT MECHANISMS OF KOLAVIRON: STUDIES ON SERUM LIPOPROTEIN OXIDATION, METAL CHELATION AND OXIDATIVE MEMBRANE DAMAGE IN RATS
  23. The Garcinia kola biflavonoid kolaviron attenuates experimental hepatotoxicity induced by diclofenac
  24. Kolaviron was protective against sodium azide (NaN3) induced oxidative stress in the prefrontal cortex
  25. Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action
  26. Garcinia kola seed biflavonoid fraction (Kolaviron), increases longevityand attenuates rotenone-induced toxicity in Drosophila melanogaster
  27. Chemoprevention of aflatoxin B1-induced genotoxicity and hepatic oxidative damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seeds
  28. Possible Protective Effect of Kolaviron on CCl4-Induced Erythrocyte Damage in Rats
  29. Kolaviron Modulates cellular redox status and impairment of membrane proteinactivities induced by potassium bromate (KBrO3) in rats
  30. Antioxidantand Scavenging Activities of Flavonoid Extract (Kolaviron) of Garcinia kola Seeds

 

 

Lactoferrin

  1. Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways

 

Lactobacillus reuteri

  1. Characterization of the anti-inflammatory Lactobacillus reuteri BM36301 and its probiotic benefits on aged mice
  2. Probiotic Bacteria Induce a ‘Glow of Health’
  3. Is Gut Health the New Path to Healthy Hair Growth?
  4. Probiotic ‘glow of health’: it’s more than skin deep

 

 


Ligustri fructus

  1. Antioxidant phenolic profile from ethyl acetate fraction of Fructus Ligustri Lucidi with protection against hydrogen peroxide-induced oxidative damage in SH-SY5Y cells
  2. Ligustri Lucidi Fructus as a traditional Chinese medicine: a review of its phytochemistry and pharmacology
  3. Improvement of calcium balance by Fructus Ligustri Lucidi extract in mature female rats was associated with the induction of serum parathyroid hormone levels
  4. Fructus ligustri lucidi extracts induce human glioma cell death through regulation of Akt/mTOR pathway In Vitro and reduce glioma tumor growth in U87MG xenograft mouse model
  5. Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway
  6. The Advances in Research on the Pharmacological Effects of Fructus Ligustri Lucidi
  7. [Effects of mixture of Astragalus membranaceus, Fructus Ligustri lucidi and Eclipta prostrata on immune function in mice].
  8. Hypoglycemic effect of fructus Ligustri Lucidi
  9. Analgesic and Anti-Inflammatory Activities of Aqueous Extracts of Fructus Ligustri Lucidi
  10. Hair growth is promoted by BeauTop via expression of EGF and FGF‑7
  11. Hair growth effect of traditional Chinese medicine BeauTop on androgenetic alopecia patients: A randomized double-blind placebo-controlled clinical trial
  12. Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growth in Conjunction with Wnts Signaling

 

Lonicera japonica flower extract
  1. Prophylactic effects of Lonicera japonica extracton dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response
  2. P01.12. Prophylactic effects of Lonicera japonica extracton dextran sulfate sodium-induced colitis in a mouse model by inhibition of the Th1/Th17 response
  3. Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells
  4. Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats
  5. Anti-inflammatory effect of the aqueous extract from Lonicera japonica flower is related to inhibition of NF-kappaB activation through reducing I-kappaBalpha degradation in rat liver.
  6. Inhibition of Experimental Systemic Inflammation(Septic Inflammation) and Chronic Bronchitis by New Phytoformula BL Containing Broussonetia papyrifera and Lonicera japonica
  7. Anti-inflammatory effect of Lonicera japonica in proteinase-activated receptor 2-mediated paw edema
  8. Inhibitory Effect of Aqueous Extract from Lonicera japonica Flower on LPS-inducedInflammatoryMediators in RAW 264.7 Macrophages.
  9. Flavonoids Isolated from Flowers of Lonicera japonicaThunb. Inhibit Inflammatory Responses in BV2 Microglial Cells by Suppressing TNF‐α and IL‐β Through PI3K/Akt/NF‐kb Signaling Pathways
  10. Loniceroside C, an Antiinflammatory Saponin from Lonicera japonica
  11. Antiinflammatory activity of Lonicera japonica
  12. Lonicera Japonica Inhibits Atopy Dermatitis in NC/Nga Mouse through Regulation of iNOS by NF-κB
    Suppression
Luteolin ( From Peanut Shells )
  1. Anti-inflammatory effects of luteolin on experimental autoimmune thyroiditis in mice
  2. Luteolin reduces inflammation in Staphylococcus aureus-induced mastitis by inhibiting NF-κB activation and MMPs expression
  3. Brain “fog,” inflammationand obesity: key aspects of neuropsychiatric disorders improved by luteolin
  4. Luteolin alleviates melanogenesis through regulation of oxidative insults
  5. Luteolin protects mice from severe acute pancreatitis by exerting HO-1-mediated anti-inflammatory and antioxidant effects
  6. Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model
  7. Luteolin attenuates airway inflammation by inducing the transition of CD4+CD25– to CD4+CD25+ regulatory T cells
  8. Luteolin Prevents Solar Radiation-Induced Matrix Metalloproteinase-1 Activation in Human Fibroblasts: A Role for p38 Mitogen-Activated Protein Kinase and Interleukin-20 Released from Keratinocytes
  9. Luteolin Suppresses Cisplatin-Induced Apoptosis in Auditory Cells: Possible Mediation Through Induction of Heme Oxygenase-1 Expression
  10. Luteolin Inhibits an Endotoxin-Stimulated Phosphorylation Cascade and Proinflammatory Cytokine Production in Macrophages
  11. Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia
  12. Luteolin suppresses IL-1β-induced cytokinesand MMPs production via p38 MAPK, JNK, NF-kappaB and AP-1 activation in human synovial sarcoma cell line, SW982
  13. Luteolin Reduces Lipopolysaccharide-induced Lethal Toxicity and Expression of Proinflammatory Moleculesin Mice
  14. Luteolin Inhibits Hyperglycemia‐Induced Proinflammatory Cytokine Production and Its Epigenetic Mechanism in Human Monocytes
  15. Antiasthmatic Activity of Luteolin-7-O-glucoside from Ailanthus altissima through the Downregulation of T Helper 2 Cytokine Expression and Inhibition of Prostaglandin E2 Production in an Ovalbumin-Induced Asthma Model
  16. Luteolin suppresses inflammation-associated gene expression by blocking NF-κB and AP-1 activation pathway in mouse alveolar macrophages
  17. Anti-Inflammatory and Antipruritic Effects of Luteolin from Perilla (P. frutescens L.) Leaves
  18. Inhibitory Effect of Perilla Leaf Extract and Luteolin on Mouse Skin Tumor Promotion
  19. Luteolin inhibits myelin basic protein‐induced human mast cell activation and mast cell‐dependent stimulation of Jurkat T cells
  20. Flavonoids such as Luteolin, Fisetin and Apigenin Are Inhibitors of Interleukin-4 and Interleukin-13Production by ActivatedHuman Basophils
  21. Modulatory effects of luteolin on osteoblastic function andinflammatory mediators in osteoblastic MC3T3‐E1 cells
  22. Luteolin inhibits mast cell-mediated allergic inflammation.
  23. Chemical characterization and anti-inflammatoryactivity of luteolin glycosides isolated from lemongrass
  24. Children with autism spectrum disorders, who improved with a luteolin-containing dietary formulation, show reduced serum levels of TNF and IL-6
  25. Inhibitory Effect of Luteolin 4′-O-Glucoside from Kummerowia striata and Other Flavonoids on Interleukin-5 Bioactivity
  26. Biphasic effects of luteolin on interleukin-1β-inducedcyclooxygenase-2 expression in glioblastoma cells
  27. Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial–mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells
  28. Stimulated human melanocytes express and release interleukin‐8, which is inhibited by luteolin: relevance to early vitiligo
  29. Effects of Luteolin on the Release of Nitric Oxide and Interleukin‐6 by Macrophages Stimulated With Lipopolysaccharide From Prevotella Intermedia
  30. Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1β-induced fibroblast-like synoviocytes through regulating the activation of NF-κB and JAK/STAT-signaling pathways
  31. Luteolin suppresses IL-1β-induced cytokines and MMPs production via p38 MAPK, JNK, NF-kappaB and AP-1 activation in human synovial sarcoma cell line, SW982
  32. Luteolin inhibited the gene expression, production and secretion of MUC5AC mucin via regulation of nuclear factor kappa B signaling pathway in human airway epithelial cells
  33. Luteolinattenuates adipocyte-derived inflammatory responses viasuppression ofNF-κB/MAPK pathway
  34. Luteolin attenuates TGF-beta 1-induced epithelial-mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt-NF-kappa B-Snail pathway
Metasequoia glyptostroboides leaves and bark extract
  1. Proanthocyanidins from the bark of Metasequoia glyptostroboides ameliorate allergic contact dermatitis through directly inhibiting T cells activation and Th1/Th17 responses
  2. Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides
  3. Proanthocyanidins: novel treatment for psoriasis that reduces oxidative stress and modulates Th17 and Treg cells
  4. The Role of Flavonoids in Inhibiting Th17 Responses in Inflammatory Arthritis
  5. Flavonoids from metasequoia Glyptostroboides
  6. Antioxidant and antidermatophytic activities of essential oil and extracts of Metasequoia glyptostroboides Miki ex Hu
  7. Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides
  8. Extraction and isolation progress of total flavonoids from Metasequoia glyptostroboides hu et cheng with adsorption method
  9. Antioxidant, lipid peroxidation inhibition and free radical scavenging efficacy of a diterpenoid compound sugiol isolated from Metasequoia glyptostroboides
  10. Optimization of Extract Processing of Total Flavones of Metasequoia glyptostroboides Hu et Cheng with Uniform Design
  11. Articles : Phytochemical Constituents from Metasequoia glyptostroboids Leaves
  12. Terpenoids and Norlignans from Metasequoia glyptostroboides

Myricetin ( From Myrica rubra Extract )
  1. Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine
  2. The anthocyanin reduced Tomato Mutant Demonstrates the Role of Flavonols in Tomato Lateral Root and Root Hair Development
  3. Hair wavingnatural product: Dillenia indica seed sap
  4. Myricetin suppresses UVB-induced wrinkle formationand MMP-9 expression by inhibiting Raf
  5. Antioxidant activity of myricetin p resence of taurine
  6. Active combinations, compositions and methods for enhancing hair growth
  7. Effects of Myricetin on the Bioavaiiability and Pharmacokinetics of Tamoxifen and its Main Metabolite, 4-Hydroxytamoxifen in Rats
  8. Chemopreventive effect of Myricetin, a natural occurring compound, on colonic chronic inflammation and inflammation-driven tumorigenesis in mice
  9. Effects of Myricetin, an Antioxidant, CYP2C9, 2D6 and P-gp Inhibitor in vitro, on the Pharmacokinetics of Carvedilol in Rats
  10. Anti-inflammatory activity of myricetin-3-O-β-D-glucuronide and related compounds
  11. Myricetin inhibits IL-1β-induced inflammatory mediators in SW982 human synovial sarcoma cells
  12. Protective effect of myricetin in dextran sulphate sodium-induced murine ulcerative colitis
  13. Anti-inflammatory activity of myricetin from Diospyros lotus through suppression of NF-κB and STAT1 activation and Nrf2-mediated HO-1 induction in lipopolysaccharide-stimulated RAW264.7 macrophages
  14. Ameliorative effect of myricetinon insulin resistance in mice fed a high-fat, high-sucrose diet
  15. Myricetin: A Dietary Molecule with Diverse Biological Activities
  16. Dual Action of Myricetin on Porphyromonas gingivalis and the Inflammatory Response of Host Cells: A Promising Therapeutic Molecule for Periodontal Diseases
  17. Antinociceptive and anti-inflammatory effects of myricetin3-O-β-galactoside isolated from Davilla elliptica: involvement of the nitrergic system
  18. Effect of Trimeric Myricetin Rhamnoside (TMR) in Carrageenan‐induced Inflammation and Caecal Ligation and Puncture‐induced Lung Oxidative Stress in Mice
  19. Myricetin suppresses LPS-induced MMP expression in human gingival fibroblasts and inhibits osteoclastogenesis by downregulating NFATc1 in RANKL-induced RAW 264.7 cells
  20. MKK4 is a novel target for the inhibition of tumor necrosis factor-α-induced vascular endothelial growth factor expression by myricetin
  21. Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice
  22. Quercetin and its principalmetabolites, but notmyricetin, opposelipopolysaccharide-inducedhyporesponsivenessofthe porcine isolatedcoronary artery
  23. Myricetin prevents titanium particle-induced osteolysis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro
  24. Myricetin Protects Against Cytokine-Induced Cell Death in RIN-m5f β Cells
  25. Myricetin: biological activity related to human health
  26. Myricetin suppresses lipoteichoic acid‐induced interleukin‐1β and cyclooxygenase‐2 expression in human gingival fibroblasts
  27. Myricetin blocks lipoteichoic acid-induced COX-2 expression in human gingival fibroblasts
  28. Myricetin and quercetin are naturally occurring co-substrates of cyclooxygenases in vivo
  29. The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression
  30. Systems Pharmacology Dissection of the Protective Effect of Myricetin Against Acute Ischemia/Reperfusion-Induced Myocardial Injury in Isolated Rat Heart
  31. Research Article Myricetin Exerts Anti-osteoarthritic Effects in IL-1β Stimulated SW1353 Cells via Regulating Matrix Metalloproteinases and Modulating JNK
  32. Myricetin Down-Regulates Phorbol Ester-Induced Cyclooxygenase-2 Expression in Mouse Epidermal Cells by Blocking Activation of Nuclear Factor Kappa B
N-acetyl- glucosamine ( From Crustaceans )
  1. O-linked β-N-acetylglucosamine During Hyperglycemia Exerts Both Anti-Inflammatory and Pro-Oxidative Properties in the Endothelial System
  2. Reduction in the appearance of facial hyperpigmentation by topical N‐acetyl glucosamine
  3. The effect of N-acetyl-glucosamine on stratum corneum desquamation and water content in human skin.
  4. Topical N-Acetyl Glucosamine Affects Pigmentation-Relevant Genes in In Vitro Genomics Testing: PP-05
  5. Topical N-acetyl glucosamine and niacinamide affect pigmentation-relevantgene expression in in vitro genomics experimentation: P2600
  6. Disruption of tyrosinase glycosylation by N-acetylglucosamine and its depigmenting effects in guinea pig skin and in human skin
  7. N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis
  8. N-Acetylglucosamine Prevents IL-1β-MediatedActivation of Human Chondrocytes
  9. Modulation of N-acetylglucosaminyltransferase III, IV and V activities and alteration of the surface oligosaccharide structure of a myeloma cell line by interleukin 6
  10. Increased O-linked β-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats
  11. Phagocytosis of N-acetyl-d-glucosamine particles, a Th1 adjuvant, by RAW 264.7 cells results in MAPK activation and TNF-α, but not IL-10, production
  12. The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes – Implications for osteoarthritis
Naringenin ( From Grapefruit Seed Extract )
  1. Supplemental Naringenin Prevents Intestinal Barrier Defects and Inflammation in Colitic Mice
  2. Dietary naringenin supplementation attenuates experimental autoimmune encephalomyelitis by modulating autoimmuneinflammatory responses in mice
  3. Naringenin Inhibits UVB Irradiation-Induced Inflammation and Oxidative Stress in the Skin of Hairless Mice
  4. Naringenin is an inhibitor of T cell effector functions
  5. Naringenin inhibits osteoclastogenesis through modulation of helper T cells‐secreted IL‐4
  6. Regulation of Inflammatory Cytokinesin Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage by 7-O-Methyl-naringenin
  7. Naringenin Suppresses NeuroinflammatoryResponses Through Inducing Suppressor of CytokineSignaling 3 Expression
  8. Naringenin has anti‐inflammatory properties in macrophage and ex vivo human whole‐blood models
  9. Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines,Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling Pathway
  10. Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-κB activity in a murine model of asthma
  11. Flavonoid Naringenin: A Potential Immunomodulator for Chlamydia trachomatis Inflammation
  12. Naringenin reducesinflammatory pain in mice
  13. Anti-inflammatoryrole of naringenin in rats with ethanol induced liver injury
  14. An Eco‐Friendly Enantioselective Access to (R)‐Naringenin as Inhibitor of Proinflammatory Cytokine Release
  15. The citrus flavanone naringenin inhibitsinflammatorysignalling in glial cells and protects against neuroinflammatory injury
  16. The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation
  17. Naringenin Ameliorates Acute Inflammation by Regulating Intracellular Cytokine Degradation
  18. Naringenin improves the healing process of thermally-induced skin damage in rats
  19. In vitroHair Growth Promoting Effects of Naringenin and Hesperetin on Human Dermal Papilla Cells and Keratinocytes
  20. Citrus flavanone naringenin enhances melanogenesisthrough the activation of Wnt/β-catenin signalling in mouse melanoma cells
  21. Anti-allergic Activity of Naringenin Chalcone from a Tomato Skin Extract
  22. Skin care compositions containing naringenin and/or quercetin and a retinoid
  23. Topical Formulation Containing Naringenin: Efficacy against Ultraviolet B Irradiation-Induced SkinInflammation and Oxidative Stress in Mice
  24. The inhibitory effect of naringenin on atopic dermatitis induced by DNFB in NC/Nga mice
  25. Naringenin ameliorates skin inflammation and accelerates phenotypic reprogramming from M1 to M2 macrophage polarization in atopic dermatitis NC/Nga mouse model.
  26. Effects of Naringenin on Inflammation in Complete Freund’s Adjuvant-Induced Arthritis by Regulating Bax/Bcl-2 Balance
  27. Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice
  28. Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway
  29. Naringeninneutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy
  30. Protective Effect of Naringenin Against Lead-Induced Oxidative Stressin Rats
  31. The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-α in mouse adipocytes
  32. Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1
  33. TNF-α Blocker Effect of Naringenin-Loaded Sericin Microparticles that Are Potentially Useful in the Treatment of Psoriasis
  34. Anti-inflammatory effect of naringin and naringenin on TNF-α secretion in cultured cortical astrocytes after stimulation with LPS
  35. Naringenin promotes recovery from colonic damage through suppression of epithelial TNF-α production and induction of M2-type macrophages in colitic mice [2019]
  36. Naringenin ameliorates streptozotocin-induced diabetic rat renal impairment by downregulation of TGF-β1 and IL-1 via modulation of oxidative stress correlates with decreased apoptotic events
  37. Naringenin: an immunomodulator of Interleukin (IL)-6, IL-8, and Tumor Necrosis Factor secretion from Chlamydia trachomatis-infected macrophages and epithelial cells (110.28)
  38. INHIBITORY EFFECT OF NARINGENIN AND NARINGIN ON IL-6 AND IL-8 RELEASE: 60
naringin ( From Citrus grandis Extract )
  1. Protective Effect of Naringenin Against Lead-Induced Oxidative Stress in Rats
  2. Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells
  3. Mice pancreatic islets protection from oxidative stress induced by single-walled carbon nanotubes through naringin
  4. Amelioration of autoimmune arthritis by naringinthrough modulation of T regulatory cells and Th1/Th2 cytokines
  5. Naringin Attenuates the Development of Carrageenan-Induced Acute Lung Inflammation Through Inhibition of NF-κb, STAT3 and Pro-Inflammatory Mediators and Enhancement of IκBα and Anti-Inflammatory Cytokines
  6. Naringin protects ultraviolet B-induced skin damageby regulating p38 MAPK signal pathway
  7. Naringin, a flavanone glycoside, promotes angiogenesis and inhibits endothelial apoptosis through modulation ofinflammatory and growth factor expression in diabetic foot ulcer in rats
  8. Naringin improves random skin flap survival in rats
  9. Naringin Protects against Kainic Acid-Induced Status Epilepticus in Rats: Evidence for an Antioxidant, Anti-inflammatory and Neuroprotective Intervention
  10. A novel ultradeformable liposomes of Naringin for anti-inflammatory therapy
  11. Study on the antiinflammation and analgesia of naringin
  12. Analysis of ionizing radiation‐induced DNA damage and repair in three‐dimensional human skin model system
  13. Naringin ameliorates pentylenetetrazol-induced seizures and associated oxidative stress, inflammation, and cognitive impairment in rats: Possible mechanisms of neuroprotection
  14. Naringin prevents ultraviolet‐B radiation‐induced oxidative damage and inflammation through activation of peroxisome proliferator‐activated receptor γ in mouse embryonic fibroblast (NIH‐3T3) cells
  15. NARINGIN REVEALS AMELIORATIVE PROPERTY OVER ELEVATED OXIDATIVE STRESS LEVELS IN ANIMAL MODELS
  16. Wound healing potential of naringin ointment formulation via regulating the expression of inflammatory, apoptotic and growth mediators in experimental rats
  17. Naringin Inhibits Tumor Growth and Reduces Interleukin-6 and Tumor Necrosis Factor α Levels in Rats with Walker 256 Carcinosarcoma
  18. Anti-Inflammatory Effects of Naringin in Chronic Pulmonary Neutrophilic Inflammation in Cigarette Smoke-Exposed Rats
  19. Therapeutic effects of silymarin and naringin on methotrexate‐induced nephrotoxicity in rats: Biochemical evaluation of anti‐inflammatory,antiapoptotic, and antiautophagic properties
  20. Naringin Protects Ovalbumin-Induced Airway Inflammation in a Mouse Model of Asthma
  21. Naringin attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress and NF-κB activation in vivo and in vitro
  22. Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy, and DNA damage
  23. NARINGIN AND RUTIN PREVENT D-GALACTOSAMINE-INDUCED HEPATIC INJURY IN RATS VIA ATTENUATION OF THE INFLAMMATORY CASCADE AND OXIDATIVE STRESS
  24. Effect of naringin enzymatic hydrolysis towards naringenin on the anti-inflammatory activity of both compounds
  25. Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway
  26. Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: Possible mechanism of nephroprotection
  27. Anti-inflammatory activity of naringin and the biosynthesised naringenin by naringinase immobilized in microstructured materials in a model of DSS-induced colitis in mice
  28. Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke
  29. Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways
  30. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction
  31. Naringin ameliorates sodium arsenite-induced renal and hepatic toxicity in rats: decisive role of KIM-1, Caspase-3, TGF-β, and TNF-α
  32. Naringin rescued the TNF-α-induced inhibition of osteogenesis of bone marrow-derived mesenchymal stem cells by depressing the activation of NF-кB signaling pathway
  33. Naringin Decreases TNF-α and HMGB1 Release from LPS-Stimulated Macrophages and Improves Survival in a CLP-Induced Sepsis Mice
  34. Naringin Inhibits TNF-α Induced Oxidative Stress and Inflammatory Response in HUVECs via Nox4/NF-Κ B and PI3K/Akt Pathways
  35. Inhibition of TNF-α/IFN-γ induced RANTES expression in HaCaT cell by naringin
Oleuropein ( From Olive Leaf Extract )
  1. Oleuropein an Olive Oil Compound in Acute and Chronic Inflammation Models: Facts and Perspectives
  2. Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin
  3. Pre-Initiation Effect of Oleuropein towards Apoptotic and Oxidative Stress Levels on the Early Development of Two-Stage Skin Carcinogenesis
  4. Olive Leaf Extract and Its Main Component OleuropeinPrevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice
  5. Evaluation of Effect of Oleuropein on Skin Wound Healing in Aged Male Balb/c Mice
  6. Therapeutic Effects of Oleuropein on Wounded Skinin Young Male Balb/c Mice
  7. Oleuropein Decreases Cyclooxygenase-2 and Interleukin-17 Expression and AttenuatesInflammatory Damage in Colonic Samples from Ulcerative Colitis Patients
  8. Oleuropein inhibited Th17 response and reduced intestinal IL-17 and IFN-γ release in dextran sulfate sodium (DSS)-induced acute colitis in C57BL/6 mice
  9. Oleuropein alleviates malathion-induced oxidative stress and DNA damage in rats
  10. OC.14.4: Oleuropein Decreases Interleukin (IL)-17 and Attenuates Inflammatory Damage in Colonic Mucosa from Ulcerative Colitis Patients
  11. Oleuropein Suppresses LPS-Induced Inflammatory Responses in RAW 264.7 Cell and Zebrafish
  12. Anti-Inflammatory Effect of Oleuropein in Experimental Rat Spinal Cord Trauma
  13. Olive oil and its main phenolic micronutrient (oleuropein) prevent inflammation-induced bone loss in the ovariectomised rat
  14. Effects of oleuropein on serum inflammatory cytokines and histopathological changes in rats with pancreatitis.
  15. Oleuropein down-regulated IL-1β-inducedinflammation and oxidative stress in human synovial fibroblast cell line SW982
  16. Effect of oleuropein on cognitive deficits and changes in hippocampal brain-derived neurotrophic factor and cytokine expression in a rat model of post-traumatic stress disorder
  17. Dose–response study of effect of oleuropein, an olive oil polyphenol, in an ovariectomy/inflammationexperimental model of bone loss in the rat
  18. Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission
  19. Oleuropein inhibits the IL-1β-induced expression ofinflammatory mediators by suppressing the activation of NF-κB and MAPKs in human osteoarthritis chondrocytes
  20. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion
  21. Antioxidant Status and Anti-inflammatory Effects ofOleuropein in Streptozotocin-induced Diabetic Nephropathy in Rats
  22. Oleuropein Curtails Pulmonary Inflammation and Tissue Destruction in Models of Experimental Asthma and Emphysema
  23. The leishmanicidal activity of oleuropein is selectively regulated through inflammation– and oxidative stress-related genes
  24. Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress
  25. interleukin‐1β or interleukin‐1 receptor antagonist with osteoarthritis
  26. Oleuropein protects against ethanol-induced oxidative stress and modulates sperm quality in the rat testis
  27. Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats
  28. Antioxidant effects of oleuropein versus oxidative stress induced by ethanol in the rat intestine
  29. Oleuropein ameliorates arsenic induced oxidative stress in mice
  30. Effect of oleuropein against chemotherapy drug-induced histological changes, oxidative stress, and DNA damages in rat kidney injury
Paeoniflorin ( From White Peony Extract )
  1. Paeoniflorin inhibitsinflammatoryresponses in mice with allergic contact dermatitis by regulating the balance between inflammatory and anti-inflammatorycytokines
  2. Paeoniflorin protects against lipopolysaccharide-induced acute lung injury in mice by alleviatinginflammatory cell infiltration and microvascular permeability
  3. Paeoniflorin Inhibits Systemic Inflammation and Improves Survival in Experimental Sepsis
  4. Paeoniflorinattenuates allergic inflammation in asthmatic mice
  5. Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation
  6. Immunoregulatory Effects of PaeoniflorinExerts Anti-asthmatic Effects via Modulation of the Th1/Th2Equilibrium
  7. Oral administration of paeoniflorin attenuates allergic contact dermatitis by inhibiting dendritic cell migration and Th1 and Th17 differentiation in a mouse model
  8. Paeoniflorin suppressesinflammatory response in imiquimod-induced psoriasis-like mice and peripheral blood mononuclear cells (PBMCs) from psoriasis patients
  9. Comparative studies of paeoniflorin and albiflorin from Paeonia lactiflora on anti-inflammatory activities
  10. Paeoniflorin inhibits function and down-regulates HLA-DR and CD80 expression of human peripheral blood monocytes stimulated by RhIL-1β
  11. Paeoniflorin down-regulates ATP-induced inflammatory cytokine production and P2X7R expression on peripheral blood mononuclear cells from patients with primary Sjögren’s syndrome
  12. Paeoniflorin Protects against Ischemia-Induced Brain Damages in Rats via Inhibiting MAPKs/NF-κB-Mediated Inflammatory Responses
  13. PaeoniflorinAtttenuates Amyloidogenesis and the Inflammatory Responses in a Transgenic Mouse Model of Alzheimer’s Disease
  14. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation
  15. Paeoniflorin suppresses IL-6/Stat3 pathway via upregulation of Socs3 in dendritic cells in response to 1-chloro-2,4-dinitrobenze
  16. Paeoniflorin diminishes ConA-induced IL-8 production in primary human hepatic sinusoidal endothelial cells in the involvement of ERK1/2 and Akt phosphorylation
  17. Paeoniflorin augments systemic Candida albicans infection through inhibiting Th1 and Th17 cellexpression in a mouse model
  18. Paeoniflorin reduces neomycin-induced ototoxicity in hair cellsby suppression of reactive oxygen species generation and extracellularly regulated kinase signalization
  19. The Anti-Inflammatory Effect of Paeoniflorin on Cerebral Infarction Induced by Ischemia-Reperfusion Injury in Sprague-Dawley Rats
  20. Paeoniflorinprevents TLR2/4-mediated inflammation in type 2 diabetic nephropathy
  21. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin.
  22. The skin‐depigmenting potential of Paeonia lactiflora root extract and paeoniflorin: in vitro evaluation using reconstructed pigmented human epidermis
  23. BIOLOGICALLY ACTIVE PRINCIPLES OF CRUDE DRUGS. II. ANTI-ALLERGIC PRINCIPLES IN “SHOSEIRYU-TO” ANTI-INFLAMMATORYPROPERTIES OF PAEONIFLORIN AND ITS DERIVATIVES
  24. Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-α and IL-1βrelease and augmentation of IL-10 production
  25. Effects of recombinant human interleukin-1β on functions of peripheral blood mononuclear cells from healthy adults and the role of paeoniflorin
  26. Paeoniflorin attenuates amyloid-beta peptide-induced neurotoxicity by ameliorating oxidative stress and regulating the NGF-mediated signaling in rats
  27. Protective effect of paeoniflorinagainst oxidative stress in human retinal pigment epithelium in vitro
  28. Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats
  29. Paeoniflorin ameliorates rheumatoid arthritis in rat models through oxidative stress, inflammation and cyclooxygenase 2
  30. Inhibitory effect of paeoniflorin on methylglyoxal-mediated oxidative stress in osteoblastic MC3T3-E1 cells
  31. Effects of Paeoniflorin on Serum Levels of TNF-α、IL-6、IL-10 in Rat Hepatic Fibrosis Model
  32. Study of Blood Nourishing Effects of Albiflorin and Paeoniflorin on Blood Deficiency Mouse Model Induced by Irradiation of and Effect on Levels of IL-3,GM-CSF,IL-6 and TNF-α
  33. Pharmacological effects of Paeoniflorin and Albiflorin on IL-3, GM-CSF, IL-6 and TNF-α in the rats of syndrome of stagnation of liver qi and blood deficiency
  34. Paeoniflorin protects cells from GalN/TNF-α-induced apoptosis via ER stress and mitochondria-dependent pathways in human L02 hepatocytes
  35. [Comparative study on effects of blood enriching on mouse model of blood deficiency syndrome induced by cyclophosphamide of albiflorin, paeoniflorin on levels of GM-CSF, IL-3 and TNF-α].
  36. Paeoniflorin Antagonizes TNF-α-Induced L929 Fibroblastoma Cells Apoptosis by Inhibiting NF-κBp65 Activation
  37. Paeoniflorin alleviates TNF-α induced intestinal barrier dysfunction by inhibition of MLCK
  38. [Inhibition of Paeoniflorin on TNF-α-induced TNF-α Receptor Type I /Nuclear Factor-κB Signal Transduction in Endothelial Cells].
  39. Influence of Paeoniflorin on Contents of Interleukin – 1β,Interleukin – 4 and TNF – α in Rats with Ulcerative Colitis
  40. Paeoniflorin induces the apoptosis of human gastric carcinoma cells by inhibiting activation of NF-κB
  41. Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury

 


Perilla frutescens var. acuta (PFVA)

  1. A WD-repeat-containing putative regulatory proteinin anthocyanin biosynthesis in Perilla frutescens
  2. Plant regeneration in vitro directly from cotyledon and hypocotyl explants of Perilla frutescens and their morphological aspects
  3. STUDIES ON THE MORPHOLOGY,STRUCTURE AND DEVELOPMENT OF THE GLANDULAR HAIRS IN PERILLA FRUTESCENS (L. )BRITTON
  4. MORPHOGENESIS OF GLANDULAR HAIRS ON THE LEAVES OF PERILLA FRUTESCENS (L. ) BRITTON
  5. The promotion of hair regrowth by topical application of a Perilla frutescens extractthrough increased cell viability and antagonism of testosterone and dihydrotestosterone
  6. Active Volatile Constituents in Perilla frutescensEssential Oils and Improvement of Antimicrobial and Anti-Inflammatory Bioactivity by Fractionation
  7. Identification and quantification of essential oil content and composition, total polyphenols and antioxidant capacityof Perilla frutescens (L.) Britt
  8. Purification and identification of two novel antioxidantpeptides from perilla (Perilla frutescens L. Britton) seed protein hydrolysates
  9. In Vitro and in Vivo Effects of Macrophage-Stimulatory Polysaccharide from Leaves of Perilla frutescensvar. crispa
  10. Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions
  11. Biological evaluation of isoegomaketone isolated from Perilla frutescens and its synthetic derivatives as anti-inflammatory agents
  12. Anti-inflammatory Effect of Perilla frutescens (L.) Britton var. frutescens Extract in LPS-stimulated RAW 264.7 Macrophages
  13. Anti‑inflammatory effects of Perilla frutescensleaf extract on lipopolysaccharide‑stimulated RAW264.7 cells
  14. Inhibition of Proinflammatory Cytokine Generation in Lung Inflammation by the Leaves of Perilla frutescensand Its Constituents
  15. Perilla frutescens extractameliorates DSS-induced colitis by suppressing proinflammatory cytokines and inducing anti-inflammatory cytokines
  16. Phytochemical profiles and in vitro anti-inflammatory properties of Perilla frutescens cv. Chookyoupjaso mutants induced by mutagenesis with γ-ray
  17. Perilla frutescens Leaf ExtractInhibits Mite Major Allergen Der p 2-induced Gene Expression of Pro-Allergic and Pro-Inflammatory Cytokines in Human Bronchial Epithelial Cell BEAS-2B
  18. Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells
  19. Perilla frutescens Extracts Protects against Dextran Sulfate Sodium-Induced Murine Colitis: NF-κB, STAT3, and Nrf2 as Putative Targets
  20. Comparison of anti-inflammatory activityof extracts with supercritical carbon dioxide from radiation mutant perilla frutescens(L.) Britton and wild-type
  21. Comparison of the Anti-Inflammatory Activities of Supercritical Carbon Dioxide versus Ethanol Extracts from Leaves of Perilla frutescens Britt. Radiation Mutant
  22. Anti-inflammatory Activity of Perilla frutescens Britton Seed in RAW 264.7 Macrophages and an Ulcerative Colitis Mouse Model
  23. Triterpene Acids from the Leaves of Perilla frutescens and Their Anti-inflammatory and Antitumor-promoting Effects
  24. Rosmarinic acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model
  25. β-secretase (BACE1) inhibitors from Perilla frutescensvar. acuta
  26. Protective effect of aqueous extract of Perilla frutescenson tert-butyl hydroperoxide-induced oxidative hepatotoxicity in rats
  27. The hepatoprotection of caffeic acid and rosmarinic acid, major compounds of Perilla frutescens, against t-BHP-induced oxidative liver damage
  28. Ethanol Extract of Perilla frutescens Suppresses Allergen-Specific Th2 Responsesand Alleviates Airway Inflammation and Hyperreactivity in Ovalbumin-Sensitized Murine Model of Asthma
  29. Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium
  30. Hypolipidemic and antioxidant effects of total flavonoids of Perilla Frutescens leaves in hyperlipidemia rats induced by high-fat diet
  31. Perilla Frutescens targets intestinal permeability
    In vitro study on TNF-α stress-induced barrier dysfunction in intestinal epithelial cells


Pinocembrin ( From Alpinia katsumadai Hayata )

  1. Pinocembrin attenuates gentamicin-induced nephrotoxicityin rats
  2. Pinocembrin attenuates blood–brain barrier injury induced by global cerebral ischemia–reperfusion in rats
  3. The characteristics of therapeutic effect of pinocembrin in transient global brain ischemia/reperfusion rats
  4. Use of racemates of pinocembrin in preparing medicaments for treating stroke
  5. In vitro and in vivo protection provided by pinocembrinagainst lipopolysaccharide-induced inflammatory responses
  6. Pinocembrin attenuates hippocampal inflammation, oxidative perturbations and apoptosis in a rat model of global cerebral ischemia reperfusion
  7. Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia
  8. Protection of mice against lipopolysaccharide-induced endotoxic shock by pinocembrin is correlated with regulation of cytokine secretion
  9. Pinocembrin Protects Human Brain Microvascular Endothelial Cells against Fibrillar Amyloid- β1−40 Injury by Suppressing the MAPK/NF- κ B Inflammatory Pathways
  10. Pinocembrin Inhibits Matrix MetalloproteinaseExpression in Chondrocytes
  11. Pinocembrin attenuates lipopolysaccharideinduced inflammatory responses in Labeo rohita macrophages via the suppression of the NF-κB signalling pathway
  12. Pinocembrin, a novel histidine decarboxylase inhibitor with anti-allergic potential in in vitro
  13. Pinocembrin inhibits lipopolysaccharide-induced inflammatory mediators production in BV2 microglial cells through suppression of PI3K/Akt/NF-κB pathway
  14. Pinocembrin– flavonoid component of domestic propolis with delaying effect of the development of Alzheimer’s disease
  15. Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits
  16. THERAPEUTIC EFFECTS OF PINOCEMBRIN ON INDOMETHACIN-INDUCED GASTRIC ULCER MODEL IN RATS
  17. Pinocembrin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress induced apoptosis
  18. Protections of pinocembrin on brain mitochondriacontribute to cognitive improvement in chronic cerebral hypoperfused rats
  19. Pinocembrin Attenuates 6-OHDA-induced Neuronal CellDeath Through Nrf2/ARE Pathway in SH-SY5Y Cells
  20. Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells
  21. Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia–reperfusion both in vivo and in vitro
  22. Pinocembrin Protects SH-SY5Y Cells Against MPP+-Induced Neurotoxicity Through the Mitochondrial Apoptotic Pathway
  23. Pinocembrin reduces cardiac arrhythmiaand infarct size in rats subjected to acute myocardial ischemia/reperfusion
  24. Pinocembrin protects against β-amyloid-induced toxicityin neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis
  25. Pinocembrin attenuates MPP+-induced neurotoxicity by the induction of heme oxygenase-1 through ERK1/2 pathway
  26. Galangin and Pinocembrin from Propolis Ameliorate Insulin Resistancein HepG2 Cells via Regulating Akt/mTOR Signaling
  27. Neuroprotective effects of pinocembrin on ischemia/reperfusion-induced brain injury by inhibiting autophagy
  28. Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells
  29. Pinocembrin Protects the Brain against Ischemia-Reperfusion Injury and Reverses the Autophagy Dysfunction in the Penumbra Area
  30. Antiproliferative and apoptotic effects of pinocembrin in human prostate cancer cells
Piper nigrum extract
  1. Leishmanicidal Activity of Piper nigrum Bioactive Fractions is Interceded via Apoptosis In Vitro and Substantiated by Th1 Immunostimulatory Potential In Vivo
  2. Piper nigrum extractameliorated allergic inflammation through inhibiting Th2/Th17 responsesand mast cells activation
  3. Anti-inflammatory activityand chemical composition of dichloromethane extract from Piper nigrum and P. longum on permanent focal cerebral ischemia injury in rats
  4. Piperine inhibits cytokine production by human peripheral blood mononuclear cells
  5. Piperine is a potent inhibitor of nuclear factor-κB (NF-κB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells
  6. Alkaloids from Piper nigrum Exhibit Antiinflammatory Activity via Activating the Nrf2/HO­1 Pathway
  7. Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte
  8. Piper nigrum Fruit Extract Prevents TMA-Induced Allergic Contact Dermatitis by Regulating Th2 CytokineProduction
  9. Melanogenesis Stimulation in Murine B16 Melanoma Cells by Piper nigrum Leaf Extract and Its Lignan Constituents
  10. Alkamides from Piper longum and Piper nigrum as Inhibitors of IL-6 action
  11. Antioxidant efficacy of black pepper (Piper nigrum L.)and piperine in rats with high fat diet induced oxidative stress
  12. Methanolic Extract of Piper nigrum Fruits Improves Memory Impairment by Decreasing Brain Oxidative Stress in Amyloid Beta(1–42) Rat Model of Alzheimer’s Disease
  13. Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damagein DNA leading to cell cycle arrest and apoptosis in cancer cells
  14. γ-Aminobutyric acid (GABA) priming enhances the osmotic stress tolerance in Piper nigrum Linn. plants subjected to PEG-induced stress
  15. Antioxidant, Anti-inflammatory and Antinociceptive Properties of Black Pepper Essential Oil (Piper nigrum Linn)
  16. Polyphenolic extract of Piper nigrum inhibitssodium oxalate induced oxidative stress in rat kidney
  17. Analgesic and anti-inflammatoryactivities of Piper nigrum L.
  18. Piperine and quercetin enhances antioxidant and hepatoprotective effect of curcumin in paracetamol induced oxidative stress
  19. Piperine modulation of carcinogen induced oxidative stress in intestinal mucosa
  20. Modulation of cadmium induced alterations in murine thymocytes by piperine: Oxidative stress,apoptosis, phenotyping and blastogenesis
  21. Piperine ameliorates oxidative stress, inflammationand histological outcome in collagen induced arthritis
  22. Piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice
  23. Attenuation of beryllium induced hepatorenal dysfunction and oxidative stress in rodents by combined effect of gallic acid and piperine
  24. Quercetin along with piperine prevents cognitive dysfunction, oxidative stress and neuro-inflammation associated with mouse model of chronic unpredictable stress
  25. The use of nitroxide radical-containing nanoparticles coupled with piperine to protect neuroblastoma SH-SY5Y cells from Aβ-induced oxidative stress
  26. Piperineinhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin‐induced asthma model
  27. Caloric restriction favorably impacts metabolic and immune/inflammatory profiles in obese mice but curcumin/piperine consumption adds no further benefit
  28. Piperinesuppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model
  29. Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson’s Rat model
  30. Anti‐Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori‐Induced Chronic Gastritis in Mongolian Gerbils
  31. Inhibitory Effects of Black Pepper (Piper Nigrum) Extracts and Compounds on Human Tumor Cell Proliferation, Cyclooxygenase Enzymes, Lipid Peroxidation and Nuclear Transcription Factor-kappa-B
Plectranthus barbatus extract
  1. Inhibition of HIV-1 enzymes, antioxidant and anti-inflammatory activities of Plectranthus barbatus
  2. Protection against hepatic oxidative damage induced by iron by the aqueous extract of Plectranthus barbatus
  3. In Vitro Skin Diffusion Study of Pure Forskolin versus a Forskolin-Containing Plectranthus barbatus Root Extract


Polyporus umbellatus

  1. Studies of the Active Substances in Herbs Used for Hair Treatment. II.Isolation of Hair Regrowth Substances,Acetosyringone and Polyporusterone A and B, from Polyporus umbellatus Fries
  2. Studies on Active Substances in Herbs Used for Hair Treatment.I. Effects of Herb Extracts on Hair Growth and Isolation of an Active Substance from Polyporus umbellatus F.
  3. Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review
  4. Studies of Active Substances in Herbs Used for Hair Treatment. IV. The Structure of the Hair RegrowthSubstance, Polyporusterone A, from Polyporus umbellatus F.
  5. Diuretic activity and kidney medulla AQP1, AQP2, AQP3, V2R expression of the aqueous extract of sclerotia of Polyporus umbellatusFRIES in normal rats
  6. Inhibitory Effects of Triterpenes Isolated from Chuling (Polyporus umbellatus FRIES) on Free Radical-Induced Lysis of Red Blood Cells
  7. Polyporus umbellatus, an Edible-Medicinal Cultivated Mushroom with Multiple Developed Health-Care Products as Food, Medicine and Cosmetics: A Review
  8. Fungal species residing in the sclerotia of Polyporus umbellatus
  9. Renoprotective effect and mechanism of polysaccharide from Polyporus umbellatussclerotia on renal fibrosis
  10. TLR4-mediated activation of macrophages by the polysaccharide fraction from Polyporus umbellatus(pers.) Fries
  11. Polysaccharide purified from Polyporus umbellatus (Per) Fr induces the activation and maturation of murine bone-derived dendritic cells via toll-like receptor 4
  12. Polyporus umbellatus, an Edible-Medicinal Cultivated Mushroom with Multiple Developed Health-Care Products as Food,Medicine and Cosmetics: A Review
  13. Nutritional factors determining sclerotial formation of Polyporus umbellatus
  14. Determination of optimal carbon source and pH value for sclerotial formation of Polyporus umbellatus under artificial conditions
  15. Growth Promoting Effects of Water Extract of Armillaria mellea Rhizomorph on Myceliaof Polyporus umbellatus
  16. Nox Gene Expression and Cytochemical Localization of Hydrogen Peroxide in Polyporus umbellatusSclerotial Formation
  17. Induction of apoptosis in MCF‑7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium)
  18. New anti-inflammatory ergostane-type ecdysteroids from the sclerotium of Polyporus umbellatus
  19. Cytotoxic Steroids from Polyporus umbellatus
  20. Polyporus umbellatuspolysaccharides ameliorates carbon tetrachloride-induced hepatic injury in mice
  21. Structure and chain conformation of a neutral polysaccharide from sclerotia of Polyporus umbellatus
  22. Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus
  23. Ergosta‐4,6,8(14),22‐tetraen‐3‐one isolated from Polyporus umbellatusprevents early renal injury in aristolochic acid‐induced nephropathy rats
  24. Polyporus umbellatus inhibited tumor cell proliferation and promoted tumor cell apoptosis by down-regulating AKT in breast cancer
  25. Genetic Diversity and Evolution of Chinese Traditional Medicinal Fungus Polyporus umbellatus (Polyporales, Basidiomycota)
  26. Khz (Fusion Product of Ganoderma lucidum and Polyporus umbellatus Mycelia)Induces Apoptosis in Human Colon Carcinoma HCT116 Cells, Accompanied by an Increase in Reactive Oxygen Species, Activation of Caspase 3, and Increased Intracellular Ca2+
  27. Simultaneous determination of eight major steroids from Polyporus umbellatus by high‐performance liquidchromatography coupled with mass spectrometry detections
  28. DETERMINATION OF MUSHROOM MONOSACCHARIDES BY LIQUID CHROMATOGRAPHY MASS-SPECTROMETRY (LCMS) AND MACROPHAGE ACTIVATION BY POLYSACCHARIDES FROM Polyporus umbellatus, Fuscoporia obliqua, Cordyceps militaris AND Pleurotus ostreatus
  29. GPP (Composition of Ganoderma Lucidum Poly-saccharides and Polyporus Umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice
  30. Transcriptome analysis of genes involved in defence response in Polyporus umbellatus with Armillaria mellea infection
  31. The Study of Polyporus Umbellatus Polysaccharide Effecting on Expressions of Mouse HepA Tumor Cell P16? Rb Gene and TNF-α [J]
  32. Study of Effect of Polyporus Umbellatus and Alisma Orientalis on TGF-β_1 and TNF-α in Serum of Pulmonary Fibrosis Rat Model
Pomegranate peel extract
  1. Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota
  2. Polyphenol-rich pomegranate fruitextract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells
  3. Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athletes: A randomized controlled trial
  4. Potential Anti-Inflammatory Effects of the Hydrophilic Fraction of Pomegranate (Punica granatum L.) Seed Oil on Breast Cancer Cell Lines
  5. Effects of pomegranate juice consumption oninflammatory markers in patients with type 2 diabetes: A randomized, placebo-controlled trial
  6. Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats
  7. The Effects of Pomegranate Juice on ProinflammatoryCytokines and Physical Function in Patients With Knee Osteoarthritis
  8. Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheumatoid Arthritis patients
  9. Potential Effects of Pomegranate on Lipid Peroxidation and Pro-inflammatory Changes in Daunorubicin-induced Cardiotoxicity in Rats
  10. Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways
  11. Polyphenolics from Mango (Mangifera indica L.) and Pomegranate (Punica granatum L.) Suppress Inflammation in in vivo and in vitro Models for Colitis
  12. Does Short Term Usage of Fresh Pomegranate Juice (FPJ) Protect Cochlear Hair Cells after Cisplatin-Based Chemo-Irradiation?
  13. Hair-dyeing by using Pomegranate Hull Extract
  14. Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug
  15. Anthocyanin‐ and hydrolyzable tannin‐rich pomegranate fruit extract modulates MAPK and NF‐κB pathways and inhibits skin tumorigenesis in CD‐1 mice
  16. Protective effect of pomegranate‐derived products on UVB‐mediated damage in human reconstituted skin
  17. Protective Effects of Standardized Pomegranate (Punica granatum L.) Polyphenolic Extract in Ultraviolet-Irradiated Human Skin Fibroblasts
  18. Phenolic Compounds of Pomegranate Byproducts (Outer Skin, Mesocarp, Divider Membrane) and Their Antioxidant Activities
  19. Pomegranate Fruit Extract Inhibits UVB‐induced Inflammation and Proliferation by Modulating NF‐κB and MAPK Signaling Pathways in Mouse Skin
  20. Thermal characteristics of a water soluble extract obtained from pomegranate skin: Developing a state diagram for determining stability
  21. Synergistic growth inhibition of mouse skin tumors by pomegranatefruit extract and diallyl sulfide: Evidence for inhibition of activated MAPKs/NF-κB and reduced cell proliferation
  22. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice
  23. Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress
  24. Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages
  25. Pomegranate reverses methotrexate-induced oxidative stress and apoptosis in hepatocytes by modulating Nrf2-NF-κB pathways
  26. PomegranateByproduct Administration to Apolipoprotein E-Deficient Mice Attenuates Atherosclerosis Development as a Result of Decreased Macrophage Oxidative Stress and Reduced Cellular Uptake of Oxidized Low-Density Lipoprotein
  27. One year of pomegranate juice intake decreases oxidative stress, inflammation,and incidence of infections in hemodialysis patients: A randomized placebo-controlled trial
  28. Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson’s disease
  29. Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts
  30. Effects of a Pomegranate Fruit Extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis
  31. Effect of pomegranate seed oil on serum TNF-α level in dyslipidemic patients
  32. Pomegranate extract prevents skeletal muscle of mice against wasting induced by acute TNF‐α injection
  33. The effects of pomegranate seed oil supplementation on the PPAR gamma and GLUT4 genes expression and the serum levels of IL-6, TNF-α and hs-CRP inflammatory factors and Glycemic indexes in obese type 2 diabetic patients: randomized controlled clinical trial
  34. A Polyphenol‐rich Pomegranate Fruit Extract Suppresses NF‐κB and IL‐6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes
  35. THE EFFECT OF SIX WEEKS AEROBIC EXERCISE AND POMEGRANATE JUICE CONSUMPTION ON IL-6 IN WOMEN WHIT TYPE 2 DIABETIC
  36. Pomegranate Fruit Extract Modulates UV‐B–mediated Phosphorylation of Mitogen‐activated Protein Kinases and Activation of Nuclear Factor Kappa B in Normal Human Epidermal Keratinocytes
  37. Pomegranate fruit extract modulates UVB-induced activation of nuclear factor kappa B and phosphorylation of mitogen activated protein kinases in normal human epidermal keratinocytes
  38. 137: Evaluation of Pomegranate Polyphenol-Mediated Suppression of Nuclear Factor Kappa b (NF-KB) Activity in Prostate Cancer Cell Lines
Procyanidins B1 B2 and c1 ( from apple peel )
  1. Oral administration of apple condensed tannins delays rheumatoid arthritis development in mice via downregulation of T helper 17 (Th17) cell responses
  2. Oligomeric Procyanidins Interfere with Glycolysis of Activated T Cells. A Novel Mechanism for Inhibition of T Cell Function
  3. Grape-seed procyanidinsprevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet
  4. Cocoa Procyanidins and Human CytokineTranscription and Secretion
  5. Effect of Cocoa Procyanidins on the Secretion of Interleukin-4 in Peripheral Blood Mononuclear Cells
  6. The in vitro evaluation of isolated procyanidinsas modulators of cytokine-induced eotaxin production in human alveolar epithelial cells
  7. Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice
  8. Anti-Inflammatory Procyanidins and Triterpenes in 109 Apple Varieties
  9. Dietary Grape-Seed Procyanidins Decreased Postweaning Diarrhea by Modulating Intestinal Permeability and Suppressing Oxidative Stress in Rats
  10. Grape-Seed Procyanidins Act as AntiinflammatoryAgents in Endotoxin-Stimulated RAW 264.7 Macrophages by Inhibiting NFkB Signaling Pathway
  11. Effects of Grape Seed Procyanidins on Cytokines,Nitric Oxide Synthase and Blood-Brain Barrier After Cerebral Ischemia-Reperfusion in Mice
  12. Procyanidin B2 gallates inhibit IFN-γ and IL-17 production in T cells by suppressing T-bet and RORγt expression
  13. Multiple Cytokine Inhibition through Specific Procyanidin–EnrichedPlant Extracts: Implicationsfor the Treatment of Psoriasis, Eczema and Dermatitis
  14. Contribution of transcript stability to a conserved procyanidin-inducedcytokine response in γδ T cells
  15. Chemical Characterization of a Procyanidin-Rich Extract from Sorghum Bran and Its Effect on Oxidative Stress and Tumor Inhibition in Vivo
  16. Procyanidin B2 Protects Neurons from Oxidative, Nitrosative, and Excitotoxic Stress
  17. Antigenotoxic Effect of Grape Seed Procyanidin Extract in Fao Cells Submitted to Oxidative Stress
  18. Protective effects of grape seed procyanidin extractagainst nickel sulfate-induced apoptosis and oxidative stress in rat testes
  19. Protective effects of oligomeric and polymeric procyanidin fractions from defatted grape seeds on tert-butyl hydroperoxide-induced oxidative damage in HepG2 cells
  20. Cocoa procyanidin chain length does not determine ability to protect LDL from oxidation when monomer units are controlled
  21. Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2
  22. The protective effect of grape seed procyanidin extract against cadmium-induced renal oxidative damage in mice
  23. Grape seed procyanidin extract attenuates hypoxic pulmonary hypertension by inhibiting oxidative stress and pulmonary arterial smooth muscle cells proliferation
  24. The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice
  25. Procyanidin B2 3,3″‐di‐O‐gallate induces oxidative stress‐mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK
  26. Procyanidins from Vitis vinifera Seeds:  In Vivo Effects on Oxidative Stress
  27. Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes
  28. Anti-inflammatory effects of grape seed procyanidinB2 on a diabetic pancreas
  29. Synthesis of Procyanidin B3 and Its Anti-inflammatoryActivity. The Effect of 4-Alkoxy Group of Catechin Electrophile in the Yb(OTf)3-Catalyzed Condensation with Catechin Nucleophile
  30. Anti-inflammatory effectof procyanidin B1 on LPS-treated THP1 cells via interaction with the TLR4–MD-2 heterodimer and p38 MAPK and NF-κB signaling
  31. Effect of Procyanidins on DOMS and Blood Plasma IL-6 in College Athletes
  32. Modulation of TNF-α Secretion in Peripheral Blood Mononuclear Cells by Cocoa Flavanols and Procyanidins
  33. Effects of Hawthorn Leaf Procyanidins on Over Expressions of ICAM-1 and E-selectin in Human Umbilical Vein Endothelial Cells Induced by TNF-α

 


Psoralea corylifolia (psoralidin)

  1. Diverse role of fast growing rhizobia in growth promotionand enhancement of psoralen content in Psoralea corylifolia L
  2. Phytopharmacological assessment of medicinal properties of Psoralea corylifolia
  3. ANTIMICROBIAL ACTIVITY OF LEAF EXTRACT OF PSORALEA CORYLIFOLIA L.
  4. Polyphenols Displaying Tyrosinase Inhibition from the Seed of Psoralea corylifolia
  5. Mechanism of Cytotoxicity by Psoralea corylifolia Extract in Human Breast Carcinoma Cells
  6. In vitro enhancement of psoralen as an important anticancer compound in Psoralea corylifolia through precursor feeding
  7. Psoralea corylifolia l. an endangered medicinal plant with broad spectrum properties
  8. Preliminary Phytochemical Studies and Evaluation of Antibacterial Activity of Psoralea corylifoliaSeed Extract
  9. Phytochemical Screening and Antibacterial Potentiality of Essential Oil from Psoralea corylifoliaLinn.
  10. ANTIMICROBIAL AND ANTIOXIDANT SYNERGY OF PSORALEA CORYLIFOLIALINN.ANDPLUMBAGOZEYLANICALINN.
  11. Dietary Total Prenylflavonoids from the Fruits of Psoralea corylifolia L. Prevents Age-Related Cognitive Deficits and Down-Regulates Alzheimer’s Markers in SAMP8 Mice
  12. Antimicrobial activity in fruit extract of Psoralea corylifoliaL. on pathogenic organisms
  13. Phenolic Compounds Isolated from Psoralea corylifolia Inhibit IL-6-induced STAT3 Activation
  14. Bavachin from Psoralea corylifolia Improves Insulin-Dependent Glucose Uptake through Insulin Signaling and AMPK Activation in 3T3-L1 Adipocytes
  15. The ethanol extraction of prepared Psoralea corylifolia induces apoptosisand autophagy and alteres genes expression assayed by cDNA microarray in human prostate cancer PC‐3 cells
  16. Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells
  17. Characterization of Compounds in Psoralea corylifoliaUsing High-Performance Liquid Chromatography Diode Array Detection, Time-of-Flight Mass Spectrometry and Quadrupole Ion Trap Mass Spectrometry
  18. Psoralea corylifolia L. Attenuates Nonalcoholic Steatohepatitis in Juvenile Mouse
  19. Prenylated flavonoid‐standardized extract from seeds of Psoralea corylifolia L. activated fat browning in high‐fatdiet–induced obese mice
  20. Psoralea corylifolia extracts stimulate cholinergic-like psoralen receptors of tadpole-tail melanophores, leading to skin darkening
  21. Fabrication of anti-vitiligo ointment containing Psoralea corylifolia: in vitro and in vivo characterization
  22. Protective effects of the compounds isolated from the seed of Psoralea corylifolia on oxidative stress-induced retinal damage
  23. Psoralea corylifolia L. Seed Extract Ameliorates Streptozotocin-Induced Diabetes in Miceby Inhibition of Oxidative Stress
  24. Anti-oxidant modulation in response to gamma radiation induced oxidative stress in developing seedlings of Psoralea corylifolia L.
  25. Protective Role of Psoralea corylifolia L.Seed Extract against Hepatic Mitochondrial Dysfunction Induced by Oxidative Stress or Aging
  26. In Vivo Anti-diabetic and Anti-oxidant Potential of Psoralea corylifolia Seeds in Streptozotocin Induced Type-2 Diabetic Rats
  27. Neuroprotective effects of Psoralea corylifolia Linn seed extracts on mitochondrial dysfunction induced by 3-nitropropionic acid
  28. Prenylflavones from Psoralea corylifolia Inhibit Nitric Oxide Synthase Expression through the Inhibition of I-κB-α Degradation in Activated Microglial Cells
  29. Protective Effect of Psoralea corylifolia L. Seed Extract against Palmitate-Induced Neuronal Apoptosis in PC12 Cells
  30. Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effectsin HT22 Hippocampal Cells and BV-2 Microglia
Pterostilbene ( From Blueberry Extract )
  1. Pterostilbene surpassed resveratrol for anti-inflammatoryapplication: Potency consideration and pharmacokinetics perspective
  2. Anti-inflammatory Action of Pterostilbene Is Mediated through the p38 Mitogen-Activated Protein Kinase Pathway in Colon Cancer Cells
  3. Effects of polyphenols including curcuminoids, resveratrol, quercetin, pterostilbene, and hydroxypterostilbene on lymphocyte pro-inflammatory cytokine production of senior horses in vitro
  4. Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells
  5. Effect of resveratrol and pterostilbene on aging and longevity
  6. Pterostilbeneattenuates theinflammatory reaction induced by ischemia/reperfusion in rat heart
  7. The Inhibitory Effect of Pterostilbene on Inflammatory Responsesduring the Interaction of 3T3-L1 Adipocytes and RAW 264.7 Macrophages
  8. Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway
  9. Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity
  10. Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377
  11. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury
  12. Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway
  13. Protective effect of Pterostilbene against free radical mediated oxidative damage
  14. Pterostilbene protects against myocardial ischemia/reperfusion injury via suppressing oxidative/nitrative stress and inflammatory response
  15. Pterostilbene reduces oxidative stress, prevents hypertrophy and preserves systolic function of right ventricle in cor pulmonale model
  16. Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis
  17. Pterostilbene ameliorates insulin sensitivity, glycemic control and oxidative stress in fructose-fed diabetic rats
  18. Pterostilbene attenuates high glucose-induced oxidative injuryin hippocampal neuronal cells by activating nuclear factor erythroid 2-related factor 2
  19. Evidence for oxidative detoxication of pterostilbene and resveratrol by a laccase-like stilbene oxidase produced by Botrytis cinerea
  20. Pterostilbene, a natural dimethylated analog of resveratrol, inhibits rat aortic vascular smooth muscle cell proliferation by blocking Akt-dependent pathway
  21. Pterostilbene suppresses vascular adhesion molecule expression in TNF-α-stimulated vascular muscle cells
  22. Resveratrol and pterostilbene inhibit TNF-α stimulated activation of NF-kB and its upstream TAK1 in macrophages via modulation of sphingolipids
Quercetin ( From Sophora Japonica Extract )
  1. Quercetin suppresses proinflammatory cytokines production through MAP kinases and NF-κB pathway in lipopolysaccharide-stimulated macrophage
  2. Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages
  3. The Flavonoid Quercetin Inhibits Proinflammatory Cytokine (Tumor Necrosis Factor Alpha) Gene Expression in Normal Peripheral Blood Mononuclear Cells via Modulation of the NF-κβ System
  4. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-κB and p38 MAPK in HMC-1 human mast cell line
  5. Quercetin Reduces Inflammatory Pain: Inhibition of Oxidative Stress and Cytokine Production
  6. Quercetin Ingestion Does Not Alter Cytokine Changesin Athletes Competing in the Western States Endurance Run
  7. A comparison of the effects of kaempferol and quercetinon cytokine-induced pro-inflammatory status of cultured human endothelial cells
  8. The flavonoid, quercetin, differentially regulates Th-1 (IFNγ) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells
  9. Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway
  10. Quercetin Is More Effective than Cromolyn in Blocking Human Mast Cell Cytokine Release and Inhibits Contact Dermatitis and Photosensitivity in Humans
  11. Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect
  12. Quercetin protects mouse liver against triptolide-induced hepatic injury by restoring Th17/Treg balance through Tim-3 and TLR4-MyD88-NF-κB pathway
  13. Quercetin Inhibits Inflammatory Bone Resorption in a Mouse Periodontitis Model
  14. Tannic acid and quercetin display a therapeutic effect on atopic dermatitisvia suppression of angiogenesis and Th2 polarization. (97.7)
  15. Protective role of quercetin against cisplatin-induced hair cell damage in zebrafish embryos
  16. INHIBITION BY QUERCETIN OF THE PROMOTING EFFECT OF TELEOCIDIN ON SKIN PAPILLOMA FORMATION IN MICE INITIATED WITH 7, 12-DIMETHYLBENZ[a]ANTHRACENE
  17. Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea
  18. Quercetin, Inflammation and Immunity
  19. The Inhibitory Effect of Quercetin on IL-6 Production by LPS- Stimulated Neutrophils